Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

THBS1 THBS2 CILP SSPOP PAPLN

5.27e-08188125GO:0005201
GeneOntologyMolecularFunctionstructural molecule activity

THBS1 THBS2 CILP SSPOP PAPLN

1.07e-04891125GO:0005198
GeneOntologyMolecularFunctionpeptidase inhibitor activity

THBS1 SSPOP PAPLN

1.67e-04187123GO:0030414
GeneOntologyMolecularFunctionmolecular function inhibitor activity

THBS1 KCNV1 SSPOP PAPLN

3.21e-04596124GO:0140678
GeneOntologyMolecularFunctionpeptidase regulator activity

THBS1 SSPOP PAPLN

4.25e-04257123GO:0061134
GeneOntologyMolecularFunctionphosphatidylserine binding

THBS1 ADGRB1

8.50e-0473122GO:0001786
GeneOntologyMolecularFunctionenzyme inhibitor activity

THBS1 SSPOP PAPLN

1.95e-03435123GO:0004857
GeneOntologyMolecularFunctionmodified amino acid binding

THBS1 ADGRB1

2.35e-03122122GO:0072341
GeneOntologyMolecularFunctionendopeptidase inhibitor activity

THBS1 PAPLN

5.03e-03180122GO:0004866
GeneOntologyMolecularFunctionheparin binding

THBS1 THBS2

5.70e-03192122GO:0008201
GeneOntologyMolecularFunctionendopeptidase regulator activity

THBS1 PAPLN

6.23e-03201122GO:0061135
GeneOntologyBiologicalProcessengulfment of apoptotic cell

THBS1 ADGRB1

3.24e-0515122GO:0043652
GeneOntologyBiologicalProcessnegative regulation of angiogenesis

THBS1 THBS2 ADGRB1

1.25e-04175123GO:0016525
GeneOntologyBiologicalProcessnegative regulation of blood vessel morphogenesis

THBS1 THBS2 ADGRB1

1.31e-04178123GO:2000181
GeneOntologyBiologicalProcessnegative regulation of vasculature development

THBS1 THBS2 ADGRB1

1.36e-04180123GO:1901343
GeneOntologyBiologicalProcessphagocytosis, recognition

ADGRB1 CFP

2.64e-0442122GO:0006910
GeneOntologyBiologicalProcessapoptotic cell clearance

THBS1 ADGRB1

3.45e-0448122GO:0043277
GeneOntologyBiologicalProcessnegative chemotaxis

SEMA5B UNC5C

3.89e-0451122GO:0050919
GeneOntologyBiologicalProcessphagocytosis

THBS1 ADGRB1 CFP

4.67e-04274123GO:0006909
GeneOntologyBiologicalProcessregulation of cell junction assembly

THBS1 THBS2 ADGRB1

6.63e-04309123GO:1901888
GeneOntologyBiologicalProcessphagocytosis, engulfment

THBS1 ADGRB1

7.12e-0469122GO:0006911
GeneOntologyBiologicalProcesscirculatory system development

THBS1 THBS2 IFT122 PKD1L1 ADGRB1

8.67e-041442125GO:0072359
GeneOntologyBiologicalProcessplasma membrane invagination

THBS1 ADGRB1

9.09e-0478122GO:0099024
GeneOntologyBiologicalProcesspositive regulation of synapse assembly

THBS2 ADGRB1

1.10e-0386122GO:0051965
GeneOntologyBiologicalProcessmembrane invagination

THBS1 ADGRB1

1.13e-0387122GO:0010324
GeneOntologyBiologicalProcesspositive regulation of reactive oxygen species metabolic process

THBS1 ADGRB1

1.18e-0389122GO:2000379
GeneOntologyCellularComponentcollagen-containing extracellular matrix

THBS1 THBS2 CILP SSPOP PAPLN CFP

2.10e-07530126GO:0062023
GeneOntologyCellularComponentextracellular matrix

THBS1 THBS2 CILP SSPOP PAPLN CFP

7.34e-07656126GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

THBS1 THBS2 CILP SSPOP PAPLN CFP

7.47e-07658126GO:0030312
GeneOntologyCellularComponentplatelet alpha granule

THBS1 THBS2

1.26e-0393122GO:0031091
GeneOntologyCellularComponentbasement membrane

THBS2 PAPLN

2.15e-03122122GO:0005604
GeneOntologyCellularComponentnon-motile cilium

IFT122 PKD1L1

5.43e-03196122GO:0097730
DomainTSP_1

THBS1 THBS2 CILP SEMA5B UNC5C SSPOP PAPLN ADGRB1 CFP

6.79e-2163129PF00090
DomainTSP1_rpt

THBS1 THBS2 CILP SEMA5B UNC5C SSPOP PAPLN ADGRB1 CFP

9.17e-2165129IPR000884
DomainTSP1

THBS1 THBS2 CILP SEMA5B UNC5C SSPOP PAPLN ADGRB1 CFP

9.17e-2165129PS50092
DomainTSP1

THBS1 THBS2 CILP SEMA5B UNC5C SSPOP PAPLN ADGRB1 CFP

9.17e-2165129SM00209
DomainVWFC_1

THBS1 THBS2 SSPOP

1.43e-0636123PS01208
DomainVWC

THBS1 THBS2 SSPOP

1.69e-0638123SM00214
DomainVWFC_2

THBS1 THBS2 SSPOP

1.69e-0638123PS50184
DomainVWF_dom

THBS1 THBS2 SSPOP

2.29e-0642123IPR001007
DomainTSP_3

THBS1 THBS2

3.78e-065122PF02412
DomainThrombospondin_3-like_rpt

THBS1 THBS2

3.78e-065122IPR003367
DomainTSP3

THBS1 THBS2

3.78e-065122PS51234
DomainTSP_CTER

THBS1 THBS2

3.78e-065122PS51236
Domain-

THBS1 THBS2

3.78e-0651224.10.1080.10
DomainTSP_type-3_rpt

THBS1 THBS2

3.78e-065122IPR028974
DomainThrombospondin_C

THBS1 THBS2

3.78e-065122IPR008859
DomainTSP_C

THBS1 THBS2

3.78e-065122PF05735
DomainThrombospondin_3_rpt

THBS1 THBS2

3.78e-065122IPR017897
DomainTSPN

THBS1 THBS2

9.50e-0523122SM00210
DomainVWC

THBS1 THBS2

1.42e-0428122PF00093
DomainI-set

CILP UNC5C PAPLN

2.13e-04190123PF07679
DomainIg_I-set

CILP UNC5C PAPLN

2.13e-04190123IPR013098
DomainGPS

PKD1L1 ADGRB1

2.36e-0436122PS50221
DomainGPS

PKD1L1 ADGRB1

2.49e-0437122IPR000203
DomainIg_sub2

CILP UNC5C PAPLN

3.98e-04235123IPR003598
DomainEGF_3

THBS1 THBS2 SSPOP

3.98e-04235123PS50026
DomainIGc2

CILP UNC5C PAPLN

3.98e-04235123SM00408
DomainEGF_1

THBS1 THBS2 SSPOP

5.05e-04255123PS00022
DomainEGF_2

THBS1 THBS2 SSPOP

5.65e-04265123PS01186
DomainLaminin_G

THBS1 THBS2

6.13e-0458122IPR001791
DomainEGF_CA

THBS1 THBS2

1.34e-0386122PF07645
Domain-

THBS1 THBS2

1.63e-03951222.60.120.200
DomainIg_sub

CILP UNC5C PAPLN

2.15e-03421123IPR003599
DomainIG

CILP UNC5C PAPLN

2.15e-03421123SM00409
DomainEGF_CA

THBS1 THBS2

2.68e-03122122SM00179
DomainEGF-like_Ca-bd_dom

THBS1 THBS2

2.76e-03124122IPR001881
DomainIG_LIKE

CILP UNC5C PAPLN

3.33e-03491123PS50835
DomainIg-like_dom

CILP UNC5C PAPLN

3.56e-03503123IPR007110
Domain-

CILP UNC5C PAPLN

7.71e-036631232.60.40.10
DomainConA-like_dom

THBS1 THBS2

8.36e-03219122IPR013320
DomainIg-like_fold

CILP UNC5C PAPLN

9.16e-03706123IPR013783
DomainEGF

THBS1 THBS2

9.57e-03235122SM00181
DomainEGF-like_dom

THBS1 THBS2

1.07e-02249122IPR000742
DomainEGF-like_CS

THBS1 THBS2

1.17e-02261122IPR013032
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

THBS1 THBS2 SEMA5B SSPOP CFP

5.67e-1139115MM15165
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

THBS1 THBS2 SEMA5B SSPOP CFP

5.67e-1139115M27417
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

THBS1 THBS2 SEMA5B SSPOP CFP

1.02e-0968115M27303
PathwayREACTOME_O_LINKED_GLYCOSYLATION

THBS1 THBS2 SEMA5B SSPOP CFP

1.12e-08109115MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

THBS1 THBS2 SEMA5B SSPOP CFP

1.23e-08111115M27416
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

THBS1 THBS2 SEMA5B SSPOP CFP

4.41e-08143115M27275
PathwayREACTOME_DISEASES_OF_METABOLISM

THBS1 THBS2 SEMA5B SSPOP CFP

7.14e-07250115M27554
PathwayPID_INTEGRIN_A4B1_PATHWAY

THBS1 THBS2

2.88e-0433112M277
PathwayWP_MIRNA_TARGETS_IN_ECM_AND_MEMBRANE_RECEPTORS

THBS1 THBS2

4.91e-0443112M39565
PathwayREACTOME_SIGNALING_BY_PDGF

THBS1 THBS2

8.63e-0457112MM14713
PathwayREACTOME_SIGNALING_BY_PDGF

THBS1 THBS2

8.93e-0458112M2049
PathwayWP_P53_SIGNALING

THBS1 ADGRB1

1.12e-0365112MM15852
PathwayPID_INTEGRIN1_PATHWAY

THBS1 THBS2

1.16e-0366112M18
PathwayKEGG_P53_SIGNALING_PATHWAY

THBS1 ADGRB1

1.23e-0368112M6370
PathwayKEGG_ECM_RECEPTOR_INTERACTION

THBS1 THBS2

1.86e-0384112M7098
PathwayKEGG_TGF_BETA_SIGNALING_PATHWAY

THBS1 THBS2

1.95e-0386112M2642
PathwayWP_BARDETBIEDL_SYNDROME

IFT122 PKD1L1

2.04e-0388112M45557
PathwayWP_P53_TRANSCRIPTIONAL_GENE_NETWORK

THBS1 ADGRB1

2.43e-0396112M40062
PathwayWP_COMPLEMENT_SYSTEM

THBS1 CFP

2.43e-0396112M39581
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

THBS1 THBS2 SEMA5B SSPOP CFP

2.56e-031389115MM15307
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

THBS1 THBS2 SEMA5B SSPOP CFP

3.35e-031475115M19806
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

THBS1 THBS2 CILP

3.58e-03418113MM15587
PathwayKEGG_AXON_GUIDANCE

SEMA5B UNC5C

4.33e-03129112M5539
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

THBS1 THBS2 CILP

7.03e-03532113M27870
PathwayWP_CILIOPATHIES

IFT122 PKD1L1

8.62e-03184112M39880
PathwayWP_FOCAL_ADHESION

THBS1 THBS2

8.90e-03187112MM15913
PathwayWP_FOCAL_ADHESION

THBS1 THBS2

1.00e-02199112M39402
PathwayKEGG_FOCAL_ADHESION

THBS1 THBS2

1.00e-02199112M7253
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

THBS1 THBS2 SEMA5B SSPOP PAPLN ADGRB1 CFP

1.28e-167512720637190
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

THBS1 THBS2 SEMA5B UNC5C PAPLN

5.86e-0921012516537572
Pubmed

Induced thrombospondin expression in the mouse pancreas during pancreatic injury.

THBS1 THBS2

1.09e-07212216181801
Pubmed

Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis.

THBS1 THBS2

1.09e-07212215037577
Pubmed

THBS1 and THBS2 Enhance the In Vitro Proliferation, Adhesion, Migration and Invasion of Intrahepatic Cholangiocarcinoma Cells.

THBS1 THBS2

1.09e-07212238339060
Pubmed

Expression of thrombospondin-1 in ischemia-induced retinal neovascularization.

THBS1 THBS2

1.09e-07212210027393
Pubmed

Immunochemical analysis of the structure of the signature domains of thrombospondin-1 and thrombospondin-2 in low calcium concentrations.

THBS1 THBS2

1.09e-07212217620335
Pubmed

Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Temporal Lobe Epilepsy Before and After Surgery.

THBS1 THBS2

1.09e-07212233372257
Pubmed

An association study of thrombospondin 1 and 2 SNPs with coronary artery disease and myocardial infarction among South Indians.

THBS1 THBS2

1.09e-07212221762961
Pubmed

TSP1 and TSP2 Have Unique and Overlapping Roles in Protecting against Noise-Induced Auditory Synaptopathy.

THBS1 THBS2

1.09e-07212230928339
Pubmed

Human cytomegalovirus infection modulates thrombospondins 1 and 2 in primary fetal astrocytes.

THBS1 THBS2

1.09e-07212223660684
Pubmed

Restricted localization of thrombospondin-2 protein during mouse embryogenesis: a comparison to thrombospondin-1.

THBS1 THBS2

1.09e-0721229694593
Pubmed

Increased excitatory connectivity and epileptiform activity in thrombospondin1/2 knockout mice following cortical trauma.

THBS1 THBS2

1.09e-07212239122122
Pubmed

Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts.

THBS1 THBS2

1.09e-07212234425286
Pubmed

The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice.

THBS1 THBS2

1.09e-07212212213711
Pubmed

Thrombospondin-1 (TSP1)-null and TSP2-null mice exhibit lower intraocular pressures.

THBS1 THBS2

1.09e-07212222930728
Pubmed

Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization.

THBS1 THBS2

1.09e-07212217143334
Pubmed

Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Common Brain Tumors.

THBS1 THBS2

1.09e-07212233759165
Pubmed

Modulation of thrombospondin expression during differentiation of embryonal carcinoma cells.

THBS1 THBS2

1.09e-0721228126073
Pubmed

Contribution of Thrombospondin-1 and -2 to Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.

THBS1 THBS2

1.09e-07212233981184
Pubmed

Thrombospondin expression in aldosterone-producing adenomas.

THBS1 THBS2

1.09e-07212212358136
Pubmed

Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke.

THBS1 THBS2

1.09e-07212218594557
Pubmed

A second, expressed thrombospondin gene (Thbs2) exists in the mouse genome.

THBS1 THBS2

1.09e-0721221712771
Pubmed

Reduced expression of thrombospondins and craniofacial dysmorphism in mice overexpressing Fra1.

THBS1 THBS2

3.27e-07312216598380
Pubmed

Increased sensitivity to kindling in mice lacking TSP1.

THBS1 THBS2

3.27e-07312226241338
Pubmed

Expression and function of thrombospondin-1 in myelinating glial cells of the central nervous system.

THBS1 THBS2

3.27e-0731229373030
Pubmed

Differential Expression Pattern of THBS1 and THBS2 in Lung Cancer: Clinical Outcome and a Systematic-Analysis of Microarray Databases.

THBS1 THBS2

3.27e-07312227513329
Pubmed

Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury.

THBS1 THBS2

3.27e-07312218787106
Pubmed

Regulation of VEGF-A, VEGFR-I, thrombospondin-1, -2, and -3 expression in a human pituitary cell line (HP75) by TGFbeta1, bFGF, and EGF.

THBS1 THBS2

3.27e-07312215347840
Pubmed

TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro.

THBS1 THBS2

3.27e-07312230939949
Pubmed

Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells.

THBS1 THBS2

3.27e-07312218032585
Pubmed

Polymorphisms in thrombospondin genes and myocardial infarction: a case-control study and a meta-analysis of available evidence.

THBS1 THBS2

3.27e-07312218178577
Pubmed

Association between single nucleotide polymorphisms in thrombospondins genes and coronary artery disease: A meta-analysis.

THBS1 THBS2

3.27e-07312225976449
Pubmed

Interactions between CD47 and thrombospondin reduce inflammation.

THBS1 THBS2

3.27e-07312217442977
Pubmed

Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.

THBS1 THBS2

3.27e-07312219004835
Pubmed

Differential expression of thrombospondin 1, 2, and 3 during murine development.

THBS1 THBS2

3.27e-0731228400410
Pubmed

Thrombospondin is a tight-binding competitive inhibitor of neutrophil elastase.

THBS1 THBS2

3.27e-0731228463250
Pubmed

The Pathological Significance and Prognostic Roles of Thrombospondin-1, and -2, and 4N1K-peptide in Bladder Cancer.

THBS1 THBS2

3.27e-07312231092423
Pubmed

Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis.

THBS1 THBS2

3.27e-07312219818485
Pubmed

Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction.

THBS1 THBS2

3.27e-07312212482844
Pubmed

A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease.

THBS1 CILP

3.27e-07312215864306
Pubmed

mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.

THBS1 THBS2

3.27e-07312234669362
Pubmed

Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers.

THBS1 THBS2

3.27e-0731221459996
Pubmed

Cocaine Triggers Astrocyte-Mediated Synaptogenesis.

THBS1 THBS2

3.27e-07312233069367
Pubmed

Thrombospondin-1, -2 and -5 have differential effects on vascular smooth muscle cell physiology.

THBS1 THBS2

3.27e-07312226168731
Pubmed

EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins.

THBS1 THBS2

3.27e-07312217638877
Pubmed

Recognition of the N-terminal modules of thrombospondin-1 and thrombospondin-2 by alpha6beta1 integrin.

THBS1 THBS2

6.55e-07412212909644
Pubmed

Thrombospondin 2 potentiates notch3/jagged1 signaling.

THBS1 THBS2

6.55e-07412219147503
Pubmed

Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior.

THBS1 THBS2

6.55e-07412211980922
Pubmed

Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity.

THBS1 THBS2

6.55e-07412210900205
Pubmed

Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.

THBS1 THBS2

6.55e-0741226338048
Pubmed

Spontaneous bacterial keratitis in CD36 knockout mice.

THBS1 THBS2

6.55e-07412220847111
Pubmed

Thrombospondin-1 and thrombospondin-2 mRNA and TSP-1 and TSP-2 protein expression in uterine fibroids and correlation to the genes COL1A1 and COL3A1 and to the collagen cross-link hydroxyproline.

THBS1 THBS2

6.55e-07412218089612
Pubmed

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.

THBS1 THBS2

1.09e-06512230622267
Pubmed

Central corneal thickness does not correlate with TonoLab-measured IOP in several mouse strains with single transgenic mutations of matricellular proteins.

THBS1 THBS2

1.09e-06512223806329
Pubmed

Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.

THBS1 THBS2

3.05e-06812224460873
Pubmed

Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development.

THBS1 THBS2

3.92e-0691221371115
Pubmed

Sema3F (Semaphorin 3F) Selectively Drives an Extraembryonic Proangiogenic Program.

THBS1 THBS2

9.91e-061412228729362
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

THBS1 THBS2 CILP

1.55e-0514612327068509
Pubmed

Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth.

THBS1 THBS2

4.72e-053012222171010
Pubmed

Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex.

THBS1 THBS2

6.45e-053512235858542
Pubmed

Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

THBS1 THBS2

1.43e-045212230389913
Pubmed

An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.

SEMA5B UNC5C

1.43e-045212226633812
Pubmed

GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.

THBS1 THBS2

1.85e-045912221421844
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

THBS1 SSPOP

2.17e-046412222261194
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

CILP SEMA5B PKD1L1 PAPLN

2.64e-0498512412975309
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

THBS1 SSPOP

2.68e-047112233541421
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

THBS1 PAPLN

3.31e-047912218757743
InteractionDPY19L3 interactions

THBS2 PAPLN CFP

3.24e-0724123int:DPY19L3
InteractionB3GLCT interactions

THBS2 PAPLN CFP

1.14e-0636123int:B3GLCT
InteractionMMP2 interactions

THBS1 THBS2 CILP

1.66e-0587123int:MMP2
InteractionTHBS2 interactions

THBS1 THBS2

5.53e-0519122int:THBS2
InteractionMMP9 interactions

THBS1 THBS2

7.03e-0467122int:MMP9
InteractionTHBS3 interactions

THBS1 THBS2

8.57e-0474122int:THBS3
CytobandEnsembl 112 genes in cytogenetic band chr3q21

IFT122 SEMA5B

7.79e-04160122chr3q21
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

UNC5C PAPLN

2.13e-0316182593
CoexpressionNABA_ECM_GLYCOPROTEINS

THBS1 THBS2 CILP SSPOP PAPLN

1.48e-08191125MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

THBS1 THBS2 CILP SSPOP PAPLN

1.69e-08196125M3008
CoexpressionNABA_CORE_MATRISOME

THBS1 THBS2 CILP SSPOP PAPLN

8.34e-08270125MM17057
CoexpressionNABA_CORE_MATRISOME

THBS1 THBS2 CILP SSPOP PAPLN

9.14e-08275125M5884
CoexpressionNABA_MATRISOME_HGSOC_OMENTAL_METASTASIS

THBS1 THBS2 CILP

2.35e-0659123M47993
CoexpressionNABA_MATRISOME

THBS1 THBS2 CILP SEMA5B SSPOP PAPLN

2.41e-061008126MM17056
CoexpressionNABA_MATRISOME

THBS1 THBS2 CILP SEMA5B SSPOP PAPLN

2.67e-061026126M5889
CoexpressionVERRECCHIA_RESPONSE_TO_TGFB1_C4

THBS1 THBS2

1.05e-0511122M566
CoexpressionGSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_UP

THBS2 KCNV1 ADGRB1

2.90e-05136123M8939
CoexpressionLIEN_BREAST_CARCINOMA_METAPLASTIC

THBS1 THBS2

1.01e-0433122M11654
CoexpressionVERRECCHIA_DELAYED_RESPONSE_TO_TGFB1

THBS1 THBS2

1.27e-0437122M16643
CoexpressionBERNARD_PPAPDC1B_TARGETS_DN

THBS1 IFT122

3.24e-0459122M8123
CoexpressionNABA_MATRISOME_PRIMARY_METASTATIC_COLORECTAL_TUMOR

THBS2 PAPLN

3.24e-0459122M47989
CoexpressionGERHOLD_ADIPOGENESIS_DN

THBS1 THBS2

3.58e-0462122M1576
CoexpressionGERHOLD_ADIPOGENESIS_DN

THBS1 THBS2

3.81e-0464122MM671
CoexpressionTURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP

THBS2 CILP

4.43e-0469122M10165
CoexpressionLI_ESTROGENE_LATE_E2_RESPONSE_DN

UNC5C SSPOP

5.95e-0480122M48218
CoexpressionNAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP

THBS1 THBS2

6.41e-0483122M17951
CoexpressionZHU_CMV_24_HR_DN

THBS1 THBS2

6.56e-0484122M4065
CoexpressionDESCARTES_FETAL_PLACENTA_SMOOTH_MUSCLE_CELLS

SEMA5B ADGRB1

7.36e-0489122M40280
CoexpressionDESCARTES_FETAL_EYE_STROMAL_CELLS

THBS1 THBS2

7.69e-0491122M40180
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_500

THBS1 THBS2 CILP UNC5C

6.11e-05412124gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#4_top-relative-expression-ranked_500

THBS2 CILP UNC5C

1.58e-04195123gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500_k4
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_1000

THBS2 CILP UNC5C

1.58e-04195123gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k4
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#3_top-relative-expression-ranked_1000

THBS2 CILP UNC5C

3.28e-04250123gudmap_developingKidney_e13.5_podocyte cells_1000_k3
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2

THBS1 THBS2 SEMA5B UNC5C CFP

3.34e-041208125facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#2_top-relative-expression-ranked_1000

THBS2 CILP UNC5C

5.86e-04305123gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k2
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#4_top-relative-expression-ranked_200

CILP UNC5C

6.53e-0468122gudmap_developingKidney_e13.5_podocyte cells_200_k4
CoexpressionAtlasBM Top 100 - lymph nodes

THBS1 PAPLN

6.53e-0468122BM Top 100 - lymph nodes
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#3_top-relative-expression-ranked_500

THBS1 THBS2

7.52e-0473122DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k3_500
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_1000

THBS1 THBS2 CILP UNC5C

8.10e-04809124gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000
CoexpressionAtlasMyeloid Cells, DC.II+480lo.PC, F4/80lo MHC II+ CD11c+ CD115+, Peritoneal Cavity, avg-3

THBS1 CFP

8.37e-0477122GSM854294_100
CoexpressionAtlasMyeloid Cells, MF.Thio5.II-480int.PC, CD115+ MHCII- F480int SiglecF- CD11c+, Peritoneal Cavity, avg-3

THBS1 CFP

9.25e-0481122GSM605865_100
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#5

THBS1 UNC5C

9.48e-0482122Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000_K5
CoexpressionAtlasMyeloid Cells, MF.Thio5.II-480hi.PC, CD115+ MHC II- F480hi Siglec F-, Peritoneal Cavity, avg-3

THBS1 CFP

9.95e-0484122GSM605862_100
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500_k-means-cluster#3

THBS1 UNC5C

9.95e-0484122Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_500_K3
CoexpressionAtlasStromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4

THBS1 THBS2

1.04e-0386122GSM777055_100
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_100

THBS1 THBS2

1.04e-0386122gudmap_developingKidney_e15.5_Pelvic Mesenchyme_100
CoexpressionAtlasratio_StemCell_vs_induced-DefinitiveEndoderm_top-relative-expression-ranked_500_k-means-cluster#4

THBS2 PAPLN

1.04e-0386122ratio_SC_vs_DE_500_K4
CoexpressionAtlasMyeloid Cells, MF.II-480hi.PC, F4/80hi CD115hi CD11b+ MHC II- CD11c-, Peritoneal Cavity, avg-3

THBS1 CFP

1.04e-0386122GSM605850_100
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

THBS1 THBS2

1.07e-0387122GSM777050_100
CoexpressionAtlasMyeloid Cells, DC.LC.Sk, MHCII+ CD11b+ CD45+, Skin, avg-2

THBS1 CFP

1.17e-0391122GSM538280_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#4_top-relative-expression-ranked_1000

THBS1 THBS2

1.27e-0395122DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k4_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#2

THBS2 SEMA5B

1.41e-03100122Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500_K2
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500_k-means-cluster#2

THBS1 SEMA5B

1.49e-03103122Facebase_RNAseq_e8.5_Paraxial Mesoderm_500_K2
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#2_top-relative-expression-ranked_500

THBS1 THBS2

1.55e-03105122gudmap_developingLowerUrinaryTract_P1_bladder_J_500_k2
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000

THBS1 THBS2 SEMA5B UNC5C

1.58e-03967124Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000

THBS1 THBS2 SEMA5B UNC5C

1.64e-03978124Facebase_RNAseq_e10.5_Mandibular Arch_1000
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

THBS1 THBS2 CILP

1.66e-03437123GSM777046_500
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

THBS1 THBS2 CILP UNC5C

9.07e-08168124aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS1 THBS2 UNC5C PAPLN

1.49e-0719012445df8fee00f8949937863159d7aa042e72748d9b
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

THBS1 THBS2 CILP UNC5C

1.61e-07194124d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 CILP UNC5C

1.18e-05172123e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 THBS2 UNC5C

1.35e-05180123fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 THBS2 UNC5C

1.35e-05180123280ff5c8f292be1b88120db5ff1788b750644856
ToppCellfacs-Marrow-B-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 SEMA5B ADGRB1

1.35e-05180123c54af6fb11484dacd3efa1f10a487376ff820a5e
ToppCellfacs-Marrow-B-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 SEMA5B ADGRB1

1.35e-0518012307ac979b21be2425294d9818c48b5a1e6f014c19
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.44e-05184123c9d7ec17cc5b7ba1b1e721ca392746e8f4a3d41f
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS2 CILP UNC5C

1.46e-051851238f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

THBS2 CILP UNC5C

1.46e-05185123fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 CILP PAPLN

1.46e-0518512387c416d14ca6255bee39b16e7571553e36ee3069
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

THBS2 SEMA5B UNC5C

1.49e-05186123cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 THBS2 PAPLN

1.49e-051861235473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

THBS1 THBS2 UNC5C

1.51e-05187123464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS1 THBS2 UNC5C

1.56e-05189123e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCell(2)_Fibroblasts-(22)_Fibro-3|World / Cell class and subclass of bone marrow stroma cells in homeostatis

THBS2 CILP KCNV1

1.59e-051901233aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

THBS1 THBS2 UNC5C

1.59e-051901233a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCelldroplet-Limb_Muscle|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.59e-0519012306c2b13fa88abbcb8086f13b8d98a156e41e4198
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.59e-05190123ad0f5605db6b694445ec9bd5dc8d2d834358c0f9
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS1 THBS2 UNC5C

1.59e-05190123d60395739458d7f47a3350ade751fe3819500320
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS2 CILP SEMA5B

1.59e-0519012373d94fbae92029745989a8712eed8b99fd84c193
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.61e-05191123b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS1 THBS2 UNC5C

1.61e-05191123b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.61e-051911231b26056df078674f37a6c06f6256b30cfcec21a7
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

THBS2 SEMA5B UNC5C

1.61e-0519112378c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THBS1 THBS2 PAPLN

1.61e-0519112308720998aa55131d7377c4c67c4c935865bd7d79
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 THBS2 UNC5C

1.64e-051921234022f208eb5db760abd0aac782a25e8ab63efc64
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.64e-05192123840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS1 THBS2 UNC5C

1.64e-05192123162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 THBS2 UNC5C

1.64e-051921239333aba0d04203ccccad78d82bf6359922f810a7
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.64e-05192123b35f0e422070ba9c7c1d9ff3eace4edc10286cde
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.64e-0519212311088878043a6ff95ba1970361256a82e434b80a
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.64e-05192123671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS1 UNC5C PAPLN

1.64e-05192123df1545670370fb1010c567cd059c2783eab315f7
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS1 THBS2 UNC5C

1.64e-051921234e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

THBS2 CILP UNC5C

1.64e-05192123e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS1 THBS2 UNC5C

1.64e-05192123ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.66e-0519312349600db68ed65cafc67bd45a285b364e4f5f88af
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 CILP PAPLN

1.66e-05193123b05361ffe111a38cfa26eb86e4ae62c15ac99b7b
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.66e-0519312345b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

THBS1 THBS2 UNC5C

1.69e-0519412303a269f75a481ea54aea8e6444605db8d6df493d
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-3|TCGA-Stomach / Sample_Type by Project: Shred V9

THBS1 THBS2 CILP

1.69e-051941232260cd817a6661e5eb6645b0c6786e18fd58371e
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBS1 SEMA5B PAPLN

1.69e-05194123c45e9d09b5cd6973de6c3f1713b3bf36fa4bfe57
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.71e-05195123d2c9c58b46bf96f9a536e177b995e340b55c6750
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CILP PAPLN ADGRB1

1.71e-051951231be9502577267ca2a04656a99d57e3e2f124d92e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.71e-051951235c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBS1 THBS2 CILP

1.71e-05195123fc43cd295f2cc3f6e9442232e028944f011c82cc
ToppCellCOVID-19-Heart-Low_count_Fib|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS1 THBS2 CILP

1.71e-05195123e09590d1f51d5fa57fceb84c9f48f84b23d4d224
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.74e-05196123fcb275746bf51269ed8ba4cf93edb054a45f1ccd
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.74e-0519612361bee32ca299219f31a30b57124e44e85b798e9f
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

THBS1 THBS2 UNC5C

1.77e-05197123fb847f2277609c31fffcdf49517243ce0684facf
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

THBS1 THBS2 UNC5C

1.77e-05197123f1c8936986123a3151140c374fcd62d6705c530b
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.77e-05197123cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBS1 THBS2 CILP

1.77e-05197123ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

THBS1 THBS2 UNC5C

1.79e-05198123df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 THBS2 PAPLN

1.79e-05198123be305d89d48c67ce922fa71aaf15e24d00c89ff6
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS1 THBS2 UNC5C

1.79e-051981233ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THBS1 THBS2 UNC5C

1.79e-0519812321cf4d81386761d09d0f6829c01c198e5524176d
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-3|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

THBS2 CILP PAPLN

1.82e-0519912307b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CILP

1.82e-05199123edd5300da1a3b758210ff8f949e9d1988b8bc7e2
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

THBS2 CILP PAPLN

1.85e-05200123e663995fc44c340d878d66b278b7b5c2ff784301
ToppCellBiopsy_Control_(H.)-Mesenchymal-Fibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

THBS2 CILP UNC5C

1.85e-052001238d75ce89393df452defacf2ec9a5bd4b7708afbb
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THBS1 THBS2 UNC5C

1.85e-05200123311fab076f2ceb258e3970eb21e39344b894042a
ToppCellBiopsy_IPF-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

THBS1 THBS2 CILP

1.85e-052001232c5626ea8fb4b702d4560117e53edf6cfcf1971e
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBS1 THBS2 CILP

1.85e-05200123a2bb67a06757f19be3f56f8cb5bb7e2affa5f4ed
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

THBS2 CILP PAPLN

1.85e-052001232cb8a39a12522a9643c6244d5e94cb4559868bb9
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THBS1 THBS2 UNC5C

1.85e-05200123cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellBiopsy_Control_(H.)-Mesenchymal|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

THBS2 CILP UNC5C

1.85e-0520012301522ed0b68614b1ebdf190957d44a9d48a6c6e3
ToppCellSkin-Fibroblasts|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

THBS1 THBS2 CILP

1.85e-05200123f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THBS1 THBS2 UNC5C

1.85e-05200123cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell5'-Adult-Distal_Rectal-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBS1 THBS2 CILP

1.85e-05200123db6281b5d4032116310db379d9175d790994c99c
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

THBS2 CILP UNC5C

1.85e-0520012354806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-3|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

THBS2 CILP PAPLN

1.85e-052001238cc5057b0e5ae9b72ea40d2ffbc52b79bf87ccef
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBS1 THBS2 CILP

1.85e-0520012310f0c20ba7c71d9e2e177597f85b41cb40f0d878
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Striatum / BrainAtlas - Mouse McCarroll V32

PKD1L1 SSPOP

1.99e-0479122a60fcbb278ba629af922c53faf58e4d96c537b15
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Trf.Ctps_(Ctps)|Striatum / BrainAtlas - Mouse McCarroll V32

PKD1L1 SSPOP

1.99e-0479122239d34f40c3a96186231f3aabd41c4988af3f372
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CILP PAPLN

3.37e-0410312239d8cfb899ca88c72ebe021d66cc21ae2eb6a1cc
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CILP PAPLN

3.37e-0410312201a7baaa0c3903bd00e37717856d2c1ac21bf2c8
ToppCell-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

THBS2 CILP

5.20e-04128122dab10774bc0532a1664fd8ac2b54cffab01be55a
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

THBS2 CILP

5.53e-04132122893b7ec2a2d8a140cc98575d1beca1189f053e9a
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

THBS2 PAPLN

5.53e-04132122560e836764ed7806fb18282dfebe434d30112a9a
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-|Striatum / BrainAtlas - Mouse McCarroll V32

THBS1 THBS2

5.70e-04134122a3547a68012d879d4dfe80394eace70808722e43
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)|Striatum / BrainAtlas - Mouse McCarroll V32

THBS1 THBS2

5.70e-041341229458e2d0dbc18d9025b66b59f3ecc2fbc5384940
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNV1 SSPOP

5.95e-041371224dcb15de821439011df1bb0bbd7682d674bd725d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNV1 SSPOP

5.95e-04137122c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THBS2 SEMA5B

6.22e-0414012217005ca714ba03d7528fe7979ffb4654a46b666c
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CILP CFP

6.67e-0414512288e463d5396a8fea2b7b1ecf3c9b144e16b35234
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CILP CFP

6.67e-04145122911fee7f27694393e348d94470a1a4e890038902
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-cDC2-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

THBS1 CFP

6.85e-04147122c5913cc351577e54536dd239a33e5f7a5cb79672
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNV1 SEMA5B

6.94e-041481225983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related|GW10 / Sample Type, Dataset, Time_group, and Cell type.

CILP PAPLN

7.22e-04151122edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC|GW10 / Sample Type, Dataset, Time_group, and Cell type.

CILP PAPLN

7.22e-041511224533bccc996395f74b16af939ce79b6fe253c073
ToppCellfacs-Lung-Endomucin-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 CFP

7.32e-04152122962f5bf632da79bd933193d3edd7d89941a85831
ToppCellMyeloid-C_(Monocyte)|World / shred on cell class and cell subclass (v4)

THBS1 CFP

7.32e-041521229145dc014ed7f154c158d454dc2b9754396afcca
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THBS1 THBS2

7.42e-0415312265641cc82883716dba0fefb749a30174a63f4da5
ToppCellfacs-Marrow-KLS-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5C SSPOP

7.51e-0415412237765512dfae557b9f6eb30a29463b93682a4404
ToppCellfacs-Lung-Endomucin-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 CFP

7.51e-041541228746663a822d93a8510081c81a8c971b51653067
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 CFP

7.51e-0415412227f76e4b3c055aa382708f1610c685f02d6d6114
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SEMA5B ADGRB1

7.61e-0415512277fdae85d36efb776db977eb424b32487ef222e4
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

THBS1 THBS2

5.83e-045082GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_9
Drugchondroitin sulfate

THBS1 THBS2 CILP SEMA5B

4.71e-05413124CID000024766
DrugDB04780

THBS1 IFT122 CFP

8.56e-05170123CID005459389
Drug2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide

THBS1 THBS2

1.17e-0431122ctd:C577942
DrugTinidazole [19387-91-8]; Up 200; 16.2uM; PC3; HT_HG-U133A

CILP ADGRB1 CFP

1.31e-041961234548_UP
DrugSulfachloropyridazine [80-32-0]; Up 200; 14uM; HL60; HT_HG-U133A

THBS1 KCNV1 ADGRB1

1.33e-041971232191_UP
DrugFosfosal [6064-83-1]; Up 200; 18.4uM; PC3; HT_HG-U133A

CILP KCNV1 ADGRB1

1.33e-041971234239_UP
DrugBetahistine mesylate [54856-23-4]; Up 200; 17.2uM; HL60; HT_HG-U133A

THBS1 THBS2 ADGRB1

1.35e-041981232472_UP
Druggenistein; Up 200; 10uM; PC3; HT_HG-U133A

KCNV1 ADGRB1 CFP

1.37e-041991234459_UP
DrugHalofantrine hydrochloride [36167-63-2]; Up 200; 7.4uM; HL60; HT_HG-U133A

THBS1 THBS2 CILP

1.39e-042001233130_UP
DrugPivmecillinam hydrochloride [32887-03-9]; Up 200; 8.4uM; HL60; HT_HG-U133A

THBS1 ADGRB1 CFP

1.39e-042001232973_UP
DrugOrlistat; Down 200; 10uM; MCF7; HT_HG-U133A

THBS1 CILP KCNV1

1.39e-042001236415_DN
Drugbiphenylene

THBS1 THBS2

1.42e-0434122CID000009214
DrugVal-Val

THBS1 THBS2

1.87e-0439122CID000107475
DrugRgd Peptide

THBS1 THBS2 ADGRB1

2.34e-04239123CID000104802
Drug1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea

THBS1 THBS2

2.83e-0448122ctd:C581572
DrugNor 3

THBS1 THBS2

3.08e-0450122CID009578441
DrugGSK1210151A

THBS1 THBS2

3.33e-0452122ctd:C568713
DiseaseLumbar disc disease

THBS2 CILP

1.52e-065122C0221775
DiseaseINTERVERTEBRAL DISC DISEASE

THBS2 CILP

1.52e-065122603932
DiseaseIntervertebral disc disorder

THBS2 CILP

1.52e-065122cv:C0158252
DiseaseIntervertebral disc disorder

THBS2 CILP

2.27e-066122C0158252
DiseaseMicroangiopathy, Diabetic

THBS1 THBS2

1.81e-0516122C0025945
DiseaseDiabetic Angiopathies

THBS1 THBS2

1.81e-0516122C0011875
Diseasecolorectal cancer (is_marker_for)

THBS1 ADGRB1

1.79e-03157122DOID:9256 (is_marker_for)
DiseaseMalignant neoplasm of breast

THBS1 SEMA5B CFP

8.27e-031074123C0006142
Diseaseamyloid-beta measurement

KCNV1 UNC5C

8.80e-03355122EFO_0005194

Protein segments in the cluster

PeptideGeneStartEntry
AWDEWSPWSLCSSTC

ADGRB1

411

O14514
LSPIWSICWNPSSRW

IFT122

176

Q9HBG6
IPDTTFTSVPCAWWW

KCNV1

371

Q6PIU1
RSPRWSLWSTWAPCS

CFP

76

P27918
WATWGPWTPCSASCH

CFP

196

P27918
SWSEWSTWGLCMPPC

CFP

381

P27918
PWWSSAVWAICGTAS

PKD1L1

2131

Q8TDX9
WTPWTSWSSCSQSCL

SSPOP

2776

A2VEC9
PSIWGLWAPWSTCSA

SSPOP

2831

A2VEC9
TWSPWTPWSQCSASC

SSPOP

3186

A2VEC9
GPWSSWSPCSRSCTD

SSPOP

3886

A2VEC9
WTSWAPWEPCSRSCG

SSPOP

3951

A2VEC9
IWSPWSPWSKCSAAC

CILP

151

O75339
GWSPWSEWTSCSTSC

THBS1

381

P07996
SDTWGPWSQWSPCSR

PAPLN

26

O95428
AWTPWSSWALCSTSC

SEMA5B

666

Q9P283
ACPVRGAWSCWTSWS

SEMA5B

906

Q9P283
GAWSCWTSWSPCSAS

SEMA5B

911

Q9P283
RWSPWSPWSACTVTC

THBS2

496

P35442
PWSKWSTCGTECTHW

UNC5C

321

O95185