Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	5.57e-06	5	166	3	GO:0030156
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-7 ERVK-21 ERVK-9 ERVK-18 ERVK-24	1.31e-05	37	166	5	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-7 ERVK-21 ERVK-9 ERVK-18 ERVK-24	1.50e-05	38	166	5	GO:0070001
GeneOntologyMolecularFunction	axon guidance receptor activity	HMCN2 ROBO1 EPHB1	1.52e-04	13	166	3	GO:0008046
GeneOntologyBiologicalProcess	cell recognition	NRCAM PRSS37 NCAM1 EXT1 ZP2 OPCML NTM VCAN ROBO1 EPHB1	5.35e-06	198	168	10	GO:0008037
GeneOntologyBiologicalProcess	neuron recognition	NRCAM NCAM1 EXT1 OPCML NTM ROBO1	8.42e-06	59	168	6	GO:0008038
GeneOntologyBiologicalProcess	synapse assembly	SLC25A46 GABRG3 CUX2 NRCAM NEGR1 LRFN5 ROBO1 CTNNB1 MDGA1 SDK1 EPHB1	4.66e-05	308	168	11	GO:0007416
GeneOntologyCellularComponent	manchette	RIMBP3 RIMBP3C RIMBP3B DYNC1H1	7.25e-05	28	169	4	GO:0002177
Domain	FN3_dom	PAPPA2 FLNC MYOM1 NRCAM COL20A1 OBSCN NCAM1 RIMBP3 IGSF22 LRFN5 FNDC11 ROBO1 RIMBP3C RIMBP3B MDGA1 USH2A SDK1 HCFC1 EPHA1 EPHB1	1.38e-15	209	160	20	IPR003961
Domain	Ig-like_fold	PAPPA2 FLNC MYOM1 NRCAM TAPBPL COL20A1 OBSCN NCAM1 OPCML RIMBP3 IGSF22 HMCN2 CD19 NEGR1 SIGIRR NTM LRFN5 FNDC11 VCAN VSIG10L FCRLB ROBO1 LSAMP RIMBP3C BCAM RIMBP3B MDGA1 USH2A SDK1 HCFC1 EPHA1 EPHB1	7.30e-15	706	160	32	IPR013783
Domain	-	PAPPA2 FLNC MYOM1 NRCAM TAPBPL COL20A1 OBSCN NCAM1 OPCML RIMBP3 IGSF22 CD19 NEGR1 SIGIRR NTM LRFN5 FNDC11 VCAN VSIG10L FCRLB ROBO1 LSAMP RIMBP3C BCAM RIMBP3B MDGA1 USH2A SDK1 HCFC1 EPHA1 EPHB1	8.85e-15	663	160	31	2.60.40.10
Domain	FN3	MYOM1 NRCAM COL20A1 OBSCN NCAM1 RIMBP3 IGSF22 LRFN5 FNDC11 ROBO1 RIMBP3C RIMBP3B MDGA1 USH2A SDK1 HCFC1 EPHA1 EPHB1	1.05e-13	199	160	18	PS50853
Domain	FN3	PAPPA2 FLNC MYOM1 NRCAM COL20A1 OBSCN NCAM1 IGSF22 ROBO1 RIMBP3C RIMBP3B MDGA1 USH2A SDK1 HCFC1 EPHA1 EPHB1	4.06e-13	185	160	17	SM00060
Domain	IGc2	MYOM1 NRCAM OBSCN NCAM1 OPCML IGSF22 HMCN2 NEGR1 NTM LRFN5 VSIG10L ROBO1 LSAMP BCAM MDGA1 SDK1	1.93e-10	235	160	16	SM00408
Domain	Ig_sub2	MYOM1 NRCAM OBSCN NCAM1 OPCML IGSF22 HMCN2 NEGR1 NTM LRFN5 VSIG10L ROBO1 LSAMP BCAM MDGA1 SDK1	1.93e-10	235	160	16	IPR003598
Domain	IG	MYOM1 NRCAM TAPBPL OBSCN NCAM1 OPCML IGSF22 HMCN2 CD19 NEGR1 NTM LRFN5 VCAN VSIG10L FCRLB ROBO1 LSAMP BCAM MDGA1 SDK1	5.83e-10	421	160	20	SM00409
Domain	Ig_sub	MYOM1 NRCAM TAPBPL OBSCN NCAM1 OPCML IGSF22 HMCN2 CD19 NEGR1 NTM LRFN5 VCAN VSIG10L FCRLB ROBO1 LSAMP BCAM MDGA1 SDK1	5.83e-10	421	160	20	IPR003599
Domain	Ig_I-set	MYOM1 NRCAM OBSCN NCAM1 OPCML IGSF22 HMCN2 NEGR1 NTM LRFN5 ROBO1 LSAMP MDGA1 SDK1	9.89e-10	190	160	14	IPR013098
Domain	I-set	MYOM1 NRCAM OBSCN NCAM1 OPCML IGSF22 HMCN2 NEGR1 NTM LRFN5 ROBO1 LSAMP MDGA1 SDK1	9.89e-10	190	160	14	PF07679
Domain	IG_LIKE	MYOM1 NRCAM TAPBPL OBSCN NCAM1 OPCML IGSF22 HMCN2 CD19 NEGR1 SIGIRR NTM LRFN5 VCAN VSIG10L FCRLB ROBO1 LSAMP BCAM MDGA1 SDK1	1.40e-09	491	160	21	PS50835
Domain	Ig-like_dom	MYOM1 NRCAM TAPBPL OBSCN NCAM1 OPCML IGSF22 HMCN2 CD19 NEGR1 SIGIRR NTM LRFN5 VCAN VSIG10L FCRLB ROBO1 LSAMP BCAM MDGA1 SDK1	2.15e-09	503	160	21	IPR007110
Domain	fn3	MYOM1 NRCAM COL20A1 OBSCN NCAM1 IGSF22 ROBO1 USH2A SDK1 EPHA1 EPHB1	1.52e-07	162	160	11	PF00041
Domain	Quinoprotein_ADH-like_supfam	FAM234A NWD1 WDR7 PCDHGB1 EML5 EIF2AK3 WDR72	3.29e-07	53	160	7	IPR011047
Domain	ig	MYOM1 NRCAM OBSCN NCAM1 OPCML NEGR1 NTM BCAM MDGA1	3.89e-05	190	160	9	PF00047
Domain	Immunoglobulin	MYOM1 NRCAM OBSCN NCAM1 OPCML NEGR1 NTM BCAM MDGA1	3.89e-05	190	160	9	IPR013151
Domain	SAM_DOMAIN	STARD13 ANKS6 L3MBTL3 EPHA1 GAREM1 EPHB1	1.67e-04	95	160	6	PS50105
Domain	SAM	STARD13 ANKS6 L3MBTL3 EPHA1 GAREM1 EPHB1	1.87e-04	97	160	6	IPR001660
Domain	Myotubularin-like_Pase_dom	MTMR12 MTMR7 MTM1	2.10e-04	14	160	3	IPR010569
Domain	PPASE_MYOTUBULARIN	MTMR12 MTMR7 MTM1	2.10e-04	14	160	3	PS51339
Domain	Myotubularin_fam	MTMR12 MTMR7 MTM1	2.10e-04	14	160	3	IPR030564
Domain	Myotub-related	MTMR12 MTMR7 MTM1	2.10e-04	14	160	3	PF06602
Domain	SAM_1	ANKS6 L3MBTL3 EPHA1 GAREM1 EPHB1	2.92e-04	68	160	5	PF00536
Domain	LamGL	PAPPA2 USH2A	4.33e-04	4	160	2	SM00560
Domain	LamG-like	PAPPA2 USH2A	4.33e-04	4	160	2	IPR006558
Domain	SAM/pointed	STARD13 ANKS6 L3MBTL3 EPHA1 GAREM1 EPHB1	5.14e-04	117	160	6	IPR013761
Domain	Glyco_transf_64	EXT1 EXTL3	7.17e-04	5	160	2	PF09258
Domain	Exostosin	EXT1 EXTL3	7.17e-04	5	160	2	PF03016
Domain	Exostosin	EXT1 EXTL3	7.17e-04	5	160	2	IPR004263
Domain	EXT_C	EXT1 EXTL3	7.17e-04	5	160	2	IPR015338
Domain	HECT	NEDD4L WWP2 NEDD4	1.55e-03	27	160	3	PF00632
Domain	HECTc	NEDD4L WWP2 NEDD4	1.55e-03	27	160	3	SM00119
Domain	HECT_dom	NEDD4L WWP2 NEDD4	1.55e-03	27	160	3	IPR000569
Domain	HECT	NEDD4L WWP2 NEDD4	1.55e-03	27	160	3	PS50237
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MTMR12 NEDD4L NRCAM WDR7 KIAA0232 GON4L FAM91A1 NEDD4 CAMKK2 TENM4 MROH1 NEGR1 MICAL3 KIF17 DYNC1H1 VPS13B PDZD2	2.73e-11	407	173	17	12693553
Pubmed	Spatiotemporal expression of IgLON family members in the developing mouse nervous system.	OPCML NEGR1 NTM LSAMP	2.95e-09	5	173	4	34599206
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	NRCAM OBSCN OPCML NEGR1 NTM LRFN5 LSAMP BCAM MDGA1	1.33e-07	162	173	9	25826454
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	UBL7 EPRS1 FLNC UTP14A ADAR SF3B1 EML5 USP54 CTNNB1 DYNC1H1	2.83e-07	232	173	10	25515538
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	4.82e-07	4	173	3	19091768
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-7 ERVK-21 ERVK-18	1.20e-06	5	173	3	12629516
Pubmed	Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins.	NEDD4L WWP2 NEDD4	1.20e-06	5	173	3	15548568
Pubmed	The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family.	NEDD4L WWP2 NEDD4	1.20e-06	5	173	3	17289006
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	1.20e-06	5	173	3	17855024
Pubmed	A Nedd4 E3 Ubiquitin Ligase Pathway Inhibits Robo1 Repulsion and Promotes Commissural Axon Guidance across the Midline.	NEDD4L NEDD4 ROBO1	1.20e-06	5	173	3	36002265
Pubmed	RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling.	NEDD4L WWP2 NEDD4 UBE2G1	1.34e-06	17	173	4	28292929
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	FLNC JADE3 OBSCN IFT46 TEP1 FASN STXBP1 SDK1 EPHB1	1.38e-06	214	173	9	22199357
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-21 ERVK-9 ERVK-18 ERVK-24	1.71e-06	18	173	4	18664271
Pubmed	Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues.	NCAM1 OPCML STXBP1 NTM LSAMP	2.11e-06	42	173	5	15146195
Pubmed	Lysosomal-associated protein transmembrane 5 ameliorates non-alcoholic steatohepatitis by promoting the degradation of CDC42 in mice.	NEDD4L WWP2 NEDD4	2.39e-06	6	173	3	37156795
Pubmed	N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel Golgi-associated protein.	NEDD4L WWP2 NEDD4	2.39e-06	6	173	3	11748237
Pubmed	N4WBP5A (Ndfip2), a Nedd4-interacting protein, localizes to multivesicular bodies and the Golgi, and has a potential role in protein trafficking.	NEDD4L WWP2 NEDD4	2.39e-06	6	173	3	15252135
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	EPRS1 FLNC NEDD4L NRCAM WDR7 NCAM1 IDH2 OPCML PHGDH FASN SF3B1 TENM4 STXBP1 NEGR1 NTM VCAN LSAMP MICAL3 USP54 CTNNB1 DYNC1H1 GOT1	2.80e-06	1431	173	22	37142655
Pubmed	Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming.	NEDD4L WWP2 NEDD4	4.17e-06	7	173	3	23644597
Pubmed	Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases.	NEDD4L WWP2 NEDD4	4.17e-06	7	173	3	11046148
Pubmed	A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.	BMP3 TENM4 MDGA1 SDK1 EPHA1 EPHB1	6.52e-06	91	173	6	28558017
Pubmed	The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel.	NEDD4L WWP2 NEDD4	6.65e-06	8	173	3	11244092
Pubmed	Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain.	NEDD4L WWP2 NEDD4	6.65e-06	8	173	3	17719543
Pubmed	DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.	NRCAM NCAM1 CTNNB1 MDGA1	8.12e-06	26	173	4	34848499
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	ADAMTS19 TICRR ZNF135 FAM234A PCNX3 OBSCN GON4L FAM91A1 ARFIP1 DALRD3 COL18A1 MROH1 VCAN NCAPD2 MICAL3 NUP188 USP54 EIF2AK3 EPHA1	1.11e-05	1215	173	19	15146197
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOCK3 FLNC ANKS6 MAN2B1 PCNX3 OBSCN EXTL3 TEP1 FASN MROH1 NCAPD2 MICAL3 NUP188 BCAM CABIN1 HCFC1 DYNC1H1 GAREM1	1.11e-05	1105	173	18	35748872
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	EPRS1 NEDD4L NRCAM DYNC2H1 EXT1 SF3B1 ROBO1 CTNNB1 SDK1 DYNC1H1	1.36e-05	358	173	10	32460013
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	EPRS1 TMEM214 ARFIP1 JMJD1C PHGDH FASN CDK5RAP3 PPP2R5D NCAPD2 ROBO1 MICAL3 EIF2AK3 HCFC1 DYNC1H1	1.36e-05	708	173	14	39231216
Pubmed	Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog.	NEDD4L WWP2 NEDD4	1.41e-05	10	173	3	25092867
Pubmed	Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway.	CUX2 DYNC2H1 ARFGEF1 UBE2G1	1.46e-05	30	173	4	27568566
Pubmed	Versican facilitates chondrocyte differentiation and regulates joint morphogenesis.	TGFBR2 VCAN CTNNB1	1.94e-05	11	173	3	20404343
Pubmed	USP11 augments TGFβ signalling by deubiquitylating ALK5.	NEDD4L WWP2 NEDD4	1.94e-05	11	173	3	22773947
Pubmed	The IgLON family of cell adhesion molecules expressed in developing neural circuits ensure the proper functioning of the sensory system in mice.	OPCML NEGR1 LSAMP	1.94e-05	11	173	3	39349721
Pubmed	ENTREP/FAM189A2 encodes a new ITCH ubiquitin ligase activator that is downregulated in breast cancer.	NEDD4L PCNX3 WWP2	1.94e-05	11	173	3	34927784
Pubmed	Dysregulated Inflammatory Signaling upon Charcot-Marie-Tooth Type 1C Mutation of SIMPLE Protein.	NEDD4L WWP2 NEDD4	1.94e-05	11	173	3	25963657
Pubmed	Gene-targeted deletion of OPCML and Neurotrimin in mice does not yield congenital heart defects.	OPCML NTM	2.46e-05	2	173	2	24616287
Pubmed	Promoter-Specific Expression and Genomic Structure of IgLON Family Genes in Mouse.	NTM LSAMP	2.46e-05	2	173	2	28210208
Pubmed	Differential AMP-activated Protein Kinase (AMPK) Recognition Mechanism of Ca2+/Calmodulin-dependent Protein Kinase Kinase Isoforms.	CAMKK1 CAMKK2	2.46e-05	2	173	2	27151216
Pubmed	Engagement of the mannose receptor by tumoral mucins activates an immune suppressive phenotype in human tumor-associated macrophages.	MRC1 MUC16	2.46e-05	2	173	2	21331365
Pubmed	Versican gene: regulation by the β-catenin signaling pathway plays a significant role in dermal papilla cell aggregative growth.	VCAN CTNNB1	2.46e-05	2	173	2	23099107
Pubmed	Mutations in the RNA Splicing Factor SF3B1 Promote Tumorigenesis through MYC Stabilization.	SF3B1 CD19	2.46e-05	2	173	2	32188705
Pubmed	Genetic analysis of the cytoplasmic dynein subunit families.	DYNC2H1 DYNC1H1	2.46e-05	2	173	2	16440056
Pubmed	Physiological Functions of the Ubiquitin Ligases Nedd4-1 and Nedd4-2.	NEDD4L NEDD4	2.46e-05	2	173	2	37962894
Pubmed	Role of Ca(2+)/calmodulin-dependent protein kinase kinase in adrenal aldosterone production.	CAMKK1 CAMKK2	2.46e-05	2	173	2	25679868
Pubmed	Biosynthesis of heparan sulfate in EXT1-deficient cells.	EXT1 EXTL3	2.46e-05	2	173	2	20377530
Pubmed	TGF-beta receptor controls B cell responsiveness and induction of IgA in vivo.	TGFBR2 CD19	2.46e-05	2	173	2	11070163
Pubmed	Nedd4 and Nedd4-2: ubiquitin ligases at work in the neuron.	NEDD4L NEDD4	2.46e-05	2	173	2	23262292
Pubmed	Down-regulating destruction: phosphorylation regulates the E3 ubiquitin ligase Nedd4-2.	NEDD4L NEDD4	2.46e-05	2	173	2	19602703
Pubmed	Inhibition of microtubules and dynein rescues human immunodeficiency virus type 1 from owl monkey TRIMCyp-mediated restriction in a cellular context-specific fashion.	DYNC2H1 DYNC1H1	2.46e-05	2	173	2	25502651
Pubmed	CDK5RAP3 acts as a tumor suppressor in gastric cancer through inhibition of β-catenin signaling.	CDK5RAP3 CTNNB1	2.46e-05	2	173	2	27793695
Pubmed	NCAPD2 inhibits autophagy by regulating Ca2+/CAMKK2/AMPK/mTORC1 pathway and PARP-1/SIRT1 axis to promote colorectal cancer.	CAMKK2 NCAPD2	2.46e-05	2	173	2	34229059
Pubmed	Calcium/calmodulin kinase kinase beta has a male-specific role in memory formation.	CAMKK1 CAMKK2	2.46e-05	2	173	2	17207577
Pubmed	Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes.	NEGR1 NTM	2.46e-05	2	173	2	32710982
Pubmed	Redirection of B cell responsiveness by transforming growth factor beta receptor.	TGFBR2 CD19	2.46e-05	2	173	2	12773615
Pubmed	Calcium/calmodulin-dependent protein kinase kinase 2 regulates macrophage-mediated inflammatory responses.	CAMKK1 CAMKK2	2.46e-05	2	173	2	22334678
Pubmed	OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer.	OPCML NTM	2.46e-05	2	173	2	12819783
Pubmed	Aberrant co-expression of CD19 and CD56 as surrogate markers of acute myeloid leukemias with t(8;21) in Taiwan.	NCAM1 CD19	2.46e-05	2	173	2	18333845
Pubmed	Neuronal cell adhesion molecule deletion induces a cognitive and behavioral phenotype reflective of impulsivity.	NRCAM NCAM1	2.46e-05	2	173	2	18081712
Pubmed	Cloning of mouse Ca2+/calmodulin-dependent protein kinase kinase beta (CaMKKbeta) and characterization of CaMKKbeta and CaMKKalpha distribution in the adult mouse brain.	CAMKK1 CAMKK2	2.46e-05	2	173	2	12654522
Pubmed	A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel.	NEDD4L NEDD4	2.46e-05	2	173	2	11149908
Pubmed	Dietary sodium modulates nephropathy in Nedd4-2-deficient mice.	NEDD4L NEDD4	2.46e-05	2	173	2	31802037
Pubmed	ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L.	NEDD4L CTNNB1	2.46e-05	2	173	2	34330894
Pubmed	Possible CaMKK-dependent regulation of AMPK phosphorylation and glucose uptake at the onset of mild tetanic skeletal muscle contraction.	CAMKK1 CAMKK2	2.46e-05	2	173	2	17213473
Pubmed	Role of beta-catenin in B cell development and function.	CD19 CTNNB1	2.46e-05	2	173	2	18768830
Pubmed	Molecular cloning and characterization of a novel human classic cadherin homologous with mouse muscle cadherin.	CTNNB1 CDH15	2.46e-05	2	173	2	9545347
Pubmed	The combined impact of IgLON family proteins Lsamp and Neurotrimin on developing neurons and behavioral profiles in mouse.	NTM LSAMP	2.46e-05	2	173	2	29605488
Pubmed	Cloning of neurotrimin defines a new subfamily of differentially expressed neural cell adhesion molecules.	OPCML NTM	2.46e-05	2	173	2	7891157
Pubmed	Aberrant expression of NEDD4L disrupts mitochondrial homeostasis by downregulating CaMKKβ in diabetic kidney disease.	NEDD4L CAMKK2	2.46e-05	2	173	2	38755664
Pubmed	A novel FLNC frameshift and an OBSCN variant in a family with distal muscular dystrophy.	FLNC OBSCN	2.46e-05	2	173	2	29073160
Pubmed	Distinct characteristics of two human Nedd4 proteins with respect to epithelial Na(+) channel regulation.	NEDD4L NEDD4	2.46e-05	2	173	2	11502596
Pubmed	Loss of catalytically inactive lipid phosphatase myotubularin-related protein 12 impairs myotubularin stability and promotes centronuclear myopathy in zebrafish.	MTMR12 MTM1	2.46e-05	2	173	2	23818870
Pubmed	Ca2+/calmodulin kinase kinase alpha is dispensable for brain development but is required for distinct memories in male, though not in female, mice.	CAMKK1 CAMKK2	2.46e-05	2	173	2	17015468
Pubmed	Vitamin D3 inhibits fatty acid synthase expression by stimulating the expression of long-chain fatty-acid-CoA ligase 3 in prostate cancer cells.	ACSL3 FASN	2.46e-05	2	173	2	15556626
Pubmed	M-cadherin-inhibited phosphorylation of ß-catenin augments differentiation of mouse myoblasts.	CTNNB1 CDH15	2.46e-05	2	173	2	23138569
Pubmed	Regulation of polyunsaturated fat induced postprandial hypercholesterolemia by a novel gene Phc-2.	H6PD ALDH4A1	2.46e-05	2	173	2	8190122
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FLNC UTP14A ADAR JMJD1C RXRB TEX36 FASN SF3B1 NCAPD2 CTNNB1 CABIN1 L3MBTL3 EIF2AK3 HCFC1 DYNC1H1	2.75e-05	857	173	15	25609649
Pubmed	A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.	EPRS1 FLNC PHGDH ACSL3 CTNNB1 DYNC1H1	2.89e-05	118	173	6	27377895
Pubmed	Multiple loci influencing hippocampal degeneration identified by genome scan.	F5 COL18A1 VPS13B	3.33e-05	13	173	3	22745009
Pubmed	Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate.	EXT1 EXTL3 COL18A1 VCAN	3.44e-05	37	173	4	32201365
Pubmed	Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.	WDR7 NCAM1 OPCML PHGDH FASN STXBP1 NTM CTNNB1 DYNC1H1 GOT1	3.72e-05	403	173	10	30562941
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	4.23e-05	14	173	3	17662146
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	EPRS1 FAM91A1 JMJD1C FASN SF3B1 ROBO1 HCFC1 DYNC1H1	4.59e-05	256	173	8	33397691
Pubmed	Mammalian α arrestins link activated seven transmembrane receptors to Nedd4 family e3 ubiquitin ligases and interact with β arrestins.	NEDD4L WWP2 NEDD4	5.27e-05	15	173	3	23236378
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	FLNC ADAP1 MAN2B1 PHGDH FASN SF3B1 MTM1 HCFC1 DYNC1H1	6.11e-05	344	173	9	30333137
Pubmed	Huntingtin interacting proteins are genetic modifiers of neurodegeneration.	OPCML STXBP1 NEGR1 NTM LSAMP CTNNB1 DYNC1H1	6.20e-05	197	173	7	17500595
Pubmed	Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases.	NEDD4L NEDD4 CTNNB1	6.46e-05	16	173	3	21920314
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	NEDD4L CAMKK1 NRCAM WDR7 NCAM1 CAMKK2 STXBP1 MICAL3 CTNNB1	6.53e-05	347	173	9	17114649
Pubmed	Regulation of Nedd4-2 self-ubiquitination and stability by a PY motif located within its HECT-domain.	NEDD4L NEDD4	7.36e-05	3	173	2	18498246
Pubmed	Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.	NEDD4L NEDD4	7.36e-05	3	173	2	21852580
Pubmed	Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l.	NEDD4L NODAL	7.36e-05	3	173	2	34475212
Pubmed	Neural Cell Adhesion Molecule Regulates Osteoblastic Differentiation Through Wnt/β-Catenin and PI3K-Akt Signaling Pathways in MC3T3-E1 Cells.	NCAM1 CTNNB1	7.36e-05	3	173	2	34054729
Pubmed	Increased intracellular calcium activates serum and glucocorticoid-inducible kinase 1 (SGK1) through a calmodulin-calcium calmodulin dependent kinase kinase pathway in Chinese hamster ovary cells.	CAMKK1 CAMKK2	7.36e-05	3	173	2	12628440
Pubmed	The mouse juvenile spermatogonial depletion (jsd) phenotype is due to a mutation in the X-derived retrogene, mUtp14b.	UTP14A ACSL3	7.36e-05	3	173	2	15289605
Pubmed	Interaction of serum- and glucocorticoid regulated kinase 1 (SGK1) with the WW-domains of Nedd4-2 is required for epithelial sodium channel regulation.	NEDD4L NEDD4	7.36e-05	3	173	2	20730100
Pubmed	Nr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesis.	NRCAM CTNNB1	7.36e-05	3	173	2	12183361
Pubmed	Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.	DYNC2H1 DYNC1H1	7.36e-05	3	173	2	8666668
Pubmed	Nodal signaling modulates the expression of Oct-4 via nuclear translocation of β-catenin in lung and prostate cancer cells.	CTNNB1 NODAL	7.36e-05	3	173	2	27592306
Pubmed	The high-affinity choline transporter CHT1 is regulated by the ubiquitin ligase Nedd4-2.	NEDD4L NEDD4	7.36e-05	3	173	2	22361880
Pubmed	Nedd4-2-mediated ubiquitination facilitates processing of surfactant protein-C.	NEDD4L NEDD4	7.36e-05	3	173	2	19423771
Pubmed	Alternative splicing determines the domain structure of WWP1, a Nedd4 family protein.	NEDD4L NEDD4	7.36e-05	3	173	2	11779188
Cytoband	22q11.21	RIMBP3 RIMBP3C MICAL3 ERVK-24 RIMBP3B	6.66e-05	111	173	5	22q11.21
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	MYOM1 NRCAM OBSCN NCAM1 OPCML IGSF22 HMCN2 NEGR1 NTM LRFN5 ROBO1 LSAMP MDGA1 SDK1	1.26e-12	161	112	14	593
GeneFamily	Fibronectin type III domain containing	MYOM1 NRCAM COL20A1 OBSCN NCAM1 IGSF22 LRFN5 ROBO1 USH2A SDK1 EPHA1 EPHB1	3.14e-10	160	112	12	555
GeneFamily	I-set domain containing\|IgLON cell adhesion molecules	OPCML NEGR1 NTM LSAMP	6.94e-09	5	112	4	1052
GeneFamily	Immunoglobulin like domain containing	NRCAM HMCN2 CD19 SIGIRR VSIG10L FCRLB BCAM MDGA1 SDK1	3.18e-06	193	112	9	594
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	MTMR12 MTMR7 MTM1	9.97e-05	15	112	3	903
GeneFamily	Exostosin glycosyltransferase family	EXT1 EXTL3	3.76e-04	5	112	2	431
GeneFamily	WD repeat domain containing	NWD1 WDR64 WDR7 TEP1 EML5 BRWD1 WDR72	1.23e-03	262	112	7	362
GeneFamily	Sterile alpha motif domain containing	ANKS6 L3MBTL3 EPHA1 EPHB1	2.18e-03	88	112	4	760
GeneFamily	Dyneins, cytoplasmic	DYNC2H1 DYNC1H1	2.84e-03	13	112	2	538
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHA1 EPHB1	3.30e-03	14	112	2	1095
GeneFamily	StAR related lipid transfer domain containing	STARD13 CERT1	3.79e-03	15	112	2	759
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	PAPPA2 CR1 VCAN	5.31e-03	57	112	3	1179
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 GABRG3 NCAM1 FLVCR2 EML5 VCAN ROBO1 LSAMP	6.78e-07	191	168	8	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 GABRG3 NCAM1 FLVCR2 EML5 VCAN ROBO1 LSAMP	6.78e-07	191	168	8	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	LA\|World / Chamber and Cluster_Paper	EXT1 SLC41A2 FASN HMCN2 NEGR1 VCAN ROBO1 SDK1	7.34e-07	193	168	8	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NRCAM COL20A1 NCAM1 OPCML NTM VCAN CHRDL1 PDZD2	8.24e-07	196	168	8	f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NRCAM COL20A1 NCAM1 OPCML NTM VCAN CHRDL1 PDZD2	8.24e-07	196	168	8	671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area\|World / Primary Cells by Cluster	PAPPA2 GABRG3 NRCAM NCAM1 NEGR1 NTM VCAN PDZD2	8.56e-07	197	168	8	79b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33\|World / Primary Cells by Cluster	PAPPA2 GABRG3 NRCAM NCAM1 NEGR1 NTM VCAN PDZD2	8.56e-07	197	168	8	d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	GABRG3 CUX2 OPCML NTM LSAMP KIAA2012 USH2A	1.40e-06	146	168	7	c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	GABRG3 CUX2 NWD1 OPCML NTM LSAMP USH2A	2.47e-06	159	168	7	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAPPA2 DYNC2H1 OBSCN MMP3 SDK1 DYRK3 PDZD2	5.40e-06	179	168	7	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK3 NRCAM ACSL3 TENM4 NTM VCAN ROBO1	6.03e-06	182	168	7	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ADAMTS19 PCDHGB1 BMP3 HMCN2 FCRLB	6.80e-06	70	168	5	e1ac00f4a519b6ada89f591e549874bd3eed0ca1
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ADAMTS19 PCDHGB1 BMP3 HMCN2 FCRLB	6.80e-06	70	168	5	27e12c0f43a996bcbed285c5ee668bef5a786d80
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ADAMTS19 PCDHGB1 BMP3 HMCN2 FCRLB	6.80e-06	70	168	5	b6815131e87e81c10e65bc398a84dab5a74b32ac
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	GABRG3 NRCAM TENM4 NEGR1 LRFN5 ROBO1 LSAMP	7.20e-06	187	168	7	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	FLNC MYOM1 OBSCN MICAL3 USP54 EIF2AK3 GAREM1	7.71e-06	189	168	7	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	FLNC MYOM1 OBSCN MICAL3 USP54 EIF2AK3 GAREM1	7.98e-06	190	168	7	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NRCAM COL20A1 NCAM1 OPCML VCAN CHRDL1 PDZD2	7.98e-06	190	168	7	6c7e1086c0a274cd5527c3104106e372811c9905
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NRCAM EXT1 COL18A1 LRFN5 VCAN LSAMP SDK1	8.26e-06	191	168	7	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	DYNC2H1 EXT1 COL18A1 TENM4 NEGR1 VCAN ROBO1	8.55e-06	192	168	7	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	NEDD4L MYOM1 OBSCN NCAM1 NTM MICAL3 PDZD2	9.14e-06	194	168	7	c3535f7cc0076653c72db582047cff053c322397
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GABRG3 TENM4 NTM LRFN5 LSAMP MICAL3 SDK1	9.14e-06	194	168	7	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRG3 CH25H OPCML BMP3 VCAN MMP3 SDK1	9.78e-06	196	168	7	1bcae4e0a244af822e2b12b2026a2771316f107d
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 NEDD4L EXT1 SDK1 VPS13B GAREM1 PDZD2	9.78e-06	196	168	7	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	myeloid-pro-pDC\|World / Lineage and Cell class	CUX2 IDH2 PHGDH FAM111B NEGR1 KIF17 EPHB1	1.01e-05	197	168	7	8918ee006b16f6b86ed33ce1dd5c0f01f51f88f5
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	NRCAM NEGR1 LRFN5 VCAN ROBO1 LSAMP SDK1	1.04e-05	198	168	7	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRCAM LRFN5 VCAN CHRDL1 ROBO1 LSAMP SDK1	1.04e-05	198	168	7	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAP1 NCAM1 PHGDH ACSL3 FASN CHRDL1 EPHB1	1.04e-05	198	168	7	43a2ce64fa309bac89a44ea320e87ae2cc39f782
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG3 NRCAM OPCML TENM4 STXBP1 NEGR1 LRFN5	1.04e-05	198	168	7	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NRCAM COL20A1 OPCML NTM VCAN CHRDL1 PDZD2	1.04e-05	198	168	7	02d0d8a212e09c0962ab1dae6a885d26d357f66a
ToppCell	Control-Fibroblasts-Mesothelial_FB\|Control / group, cell type (main and fine annotations)	GABRG3 NRCAM CR1 TENM4 LRFN5 ROBO1	1.48e-05	139	168	6	e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRG3 CUX2 WDR64 OPCML COX7B2 USH2A	2.11e-05	148	168	6	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRG3 CUX2 WDR64 OPCML COX7B2 USH2A	2.27e-05	150	168	6	0205318a870e091add66ee4305747dda9f51510d
ToppCell	BAL-Severe-cDC_4\|Severe / Compartment, Disease Groups and Clusters	MRC1 ANKS6 F5 TGFBR2 TENM4 VCAN	3.04e-05	158	168	6	73f66689ef59f71b14cb7141ca5951cc47fe57c1
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	GABRG3 CUX2 WDR64 OPCML LSAMP USH2A	3.63e-05	163	168	6	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	Frontal_cortex\|World / BrainAtlas - Mouse McCarroll V32	PAPPA2 PRSS22 BMP3 CAMKK2 CHRDL1 SDK1	3.75e-05	164	168	6	e09291711abf8680e78170328313719092b0142f
ToppCell	droplet-Fat-SCAT-30m-Lymphocytic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHGDH NXPE3 RIMBP3 LIPC CD19 DYRK3	4.01e-05	166	168	6	67370c49d7aedcb4eca802095f06b30f6bbf8919
ToppCell	droplet-Fat-SCAT-30m-Lymphocytic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHGDH NXPE3 RIMBP3 LIPC CD19 DYRK3	4.01e-05	166	168	6	7f4e5976ede6478636aa567d6fc2b56ff7295fb8
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LIPC LRFN5 MICAL3 BCAM SDK1 WDR72	4.29e-05	168	168	6	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK3 MRC1 FLNC MYOM1 OBSCN NCAM1	4.58e-05	170	168	6	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	IDH2 PHGDH FAM111B CHTF18 NCAPD2 EPHA1	4.89e-05	172	168	6	6fcc16f1067672967ecbcdfdc727649ae9891dd9
ToppCell	MS-CD8-proli_CD4\|MS / Condition, Cell_class and T cell subcluster	IFT46 FBXL6 HELB MICAL3 USP54 CABIN1	4.89e-05	172	168	6	0b6dd257110b3f17fa71ab18a165b091a9d5ae9a
ToppCell	severe_influenza-pDC\|severe_influenza / disease group, cell group and cell class (v2)	ZNF135 CUX2 SLC41A2 NTM KIF17 EPHB1	5.22e-05	174	168	6	d8d2ded5812ed3b3db4109585714a6513c13326a
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STARD13 FAM234A WDR7 EXTL3 TENM4 NTM	5.39e-05	175	168	6	1d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	DOCK3 NCAM1 F5 IGSF22 NEGR1 EPHB1	5.39e-05	175	168	6	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	DOCK3 NCAM1 F5 IGSF22 NEGR1 EPHB1	5.39e-05	175	168	6	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STARD13 FAM234A WDR7 EXTL3 TENM4 NTM	5.39e-05	175	168	6	427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DYNC2H1 CH25H NXPE3 NEDD4 STXBP1 EPHA1	5.56e-05	176	168	6	437cfc5e06416bb0fc76d1f9dc106f74e279e880
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-CD45____plasma_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAPBPL TMEM214 PHGDH LIPC NODAL DYRK3	5.74e-05	177	168	6	41cbb2c109eaa7be366fc0510cce64abc06837b4
ToppCell	Healthy/Control-pDC\|Healthy/Control / Disease group and Cell class	CUX2 SLC41A2 NEGR1 KIF17 DYRK3 EPHB1	5.92e-05	178	168	6	072b346c6bbd63f00efaceda486400a669b3ec48
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LIPC TENM4 LRFN5 MICAL3 SDK1 WDR72	5.92e-05	178	168	6	544379f5a6145429762258d426b876bb36c112f5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	F5 NTM LRFN5 VCAN ROBO1 BCAM	6.49e-05	181	168	6	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	Pericytes-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	NRCAM NCAM1 COL18A1 HMCN2 LRFN5 EPHB1	6.49e-05	181	168	6	35c470988a93381eefa300831aabb813fa1b90bd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	F5 NTM LRFN5 VCAN ROBO1 BCAM	6.49e-05	181	168	6	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CUX2 SLC41A2 NTM CHRDL1 KIF17 EPHB1	6.69e-05	182	168	6	9bbe8062aa562dc3b9c299581faf6ebbcb72a9f7
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CUX2 SLC41A2 NTM CHRDL1 KIF17 EPHB1	6.69e-05	182	168	6	4602a98df7045e2c70b7560abfba9b444fbd5d30
ToppCell	Healthy/Control-pDC\|World / Disease group and Cell class	CUX2 WDR64 SLC41A2 NEGR1 KIF17 EPHB1	6.69e-05	182	168	6	97e0eee10905f2cf2bebb09e474629fc224f4397
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK3 FLNC MYOM1 OBSCN NCAM1 MICAL3	6.69e-05	182	168	6	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	Control-Epithelial-Basal\|Control / Disease state, Lineage and Cell class	NEDD4L PRSS22 SERPINB13 MMP3 BCAM SDK1	6.69e-05	182	168	6	caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 FLVCR2 PHGDH TGFBR2 MTMR7 CTNNB1	6.69e-05	182	168	6	be48ce85991bceeff938ba080e6bf9cc62176b05
ToppCell	LPS_only-Epithelial_alveolar-AT_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRSS22 SLC41A2 BMP3 TENM4 USP54 GAREM1	6.90e-05	183	168	6	e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRCAM OBSCN TENM4 ROBO1 USH2A SDK1	7.11e-05	184	168	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRCAM OBSCN TENM4 ROBO1 USH2A SDK1	7.11e-05	184	168	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRCAM OBSCN TENM4 ROBO1 USH2A SDK1	7.11e-05	184	168	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRSS22 SLC41A2 TENM4 EML5 USP54 GAREM1	7.11e-05	184	168	6	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRSS22 SLC41A2 BMP3 TENM4 USP54 GAREM1	7.33e-05	185	168	6	fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TENM4 VCAN CHRDL1 ROBO1 CABIN1 EPHB1	7.33e-05	185	168	6	1ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS19 JADE3 OPCML VCAN KIF17 SDK1	7.33e-05	185	168	6	d5f5866924648a3c14e2596218fd548a31777aa3
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CH25H OPCML BMP3 VCAN MMP3 SDK1	7.55e-05	186	168	6	360c3e9e5c3a943e68e6939b4a47821bfc75b553
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR FAM111B NEGR1 NTM LRFN5 NCAPD2	7.77e-05	187	168	6	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	ADAMTS19 EXT1 HMCN2 NEGR1 VCAN ROBO1	7.77e-05	187	168	6	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MRC1 FLNC TGFBR2 CHRDL1 KIF17 EPHB1	7.77e-05	187	168	6	65d406122dffe18279f14a1ed35ba091730b97be
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MRC1 FLNC TGFBR2 CHRDL1 KIF17 EPHB1	7.77e-05	187	168	6	4c15c0ed41a55271fc793cb76fee97fa64190369
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MRC1 FLNC TGFBR2 CHRDL1 KIF17 EPHB1	7.77e-05	187	168	6	5274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR FAM111B NEGR1 NTM LRFN5 NCAPD2	7.77e-05	187	168	6	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ADAMTS19 NRCAM VCAN CABIN1 SDK1 EPHB1	7.77e-05	187	168	6	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPY6R NCAM1 PHGDH BMP3 COL18A1 BCAM	7.77e-05	187	168	6	806075c2531a7f5c1da38b85ea494a3b4b5e92ec
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAPPA2 OBSCN VCAN ROBO1 MMP3 SDK1	8.00e-05	188	168	6	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC1 FLVCR2 PHGDH TGFBR2 MTMR7 CTNNB1	8.24e-05	189	168	6	98f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC1 CH25H FLVCR2 PHGDH TGFBR2 CTNNB1	8.24e-05	189	168	6	b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCell	Adult\|World / Lineage, Cell type, age group and donor	MRC1 SLC41A2 FASN CDK5RAP3 MROH1 NTM	8.24e-05	189	168	6	5cd285bfad973125d46d704fec18b21266a63379
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 CH25H FLVCR2 PHGDH MTMR7 CTNNB1	8.24e-05	189	168	6	287e59104687fe1665232c52993889f0f2c97f17
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAN2B1 JMJD1C TMEM62 CD19 CCDC191 EIF2AK3	8.24e-05	189	168	6	b13f315f617840eb5143a4e8a33a657c20365c21
ToppCell	droplet-Lung-LUNG-1m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 CH25H FLVCR2 PHGDH MTMR7 CTNNB1	8.24e-05	189	168	6	6d24414ac6bd4f03f7a5ad3a6eba51d549a7b112
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC1 FLVCR2 PHGDH TGFBR2 MTMR7 CTNNB1	8.24e-05	189	168	6	f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GABRG3 NCAM1 FLVCR2 VCAN ROBO1 LSAMP	8.24e-05	189	168	6	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 GABRG3 NCAM1 FLVCR2 VCAN LSAMP	8.48e-05	190	168	6	2e592323085ba9c019d678ac2a784462ab470ed9
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GABRG3 NRCAM NTM VCAN ROBO1 SDK1	8.48e-05	190	168	6	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC1 CH25H FLVCR2 PHGDH TGFBR2 CTNNB1	8.48e-05	190	168	6	da58227565ad6a690828dd8554dd3670222f8582
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	NEGR1 LRFN5 VCAN ROBO1 LSAMP SDK1	8.48e-05	190	168	6	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FLNC MYOM1 OBSCN NCAM1 NEGR1 PDZD2	8.48e-05	190	168	6	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	OBSCN GRIK1 BMP3 COL18A1 VCAN CHRDL1	8.48e-05	190	168	6	be2b184a3559da41ba387ae0fdbeb9ae532868a5
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 GABRG3 NCAM1 FLVCR2 VCAN LSAMP	8.48e-05	190	168	6	445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	MYOM1 OBSCN NCAM1 MICAL3 GOT1 PDZD2	8.48e-05	190	168	6	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NRCAM NTM VCAN ROBO1 LSAMP SDK1	8.73e-05	191	168	6	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NWD1 NRCAM ACSL3 NTM CHRDL1 LSAMP	8.73e-05	191	168	6	fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	NRCAM NCAM1 H6PD BMP3 VCAN MICAL3	8.73e-05	191	168	6	3379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ADAMTS19 FLVCR2 ACSL3 VCAN ROBO1 SDK1	8.99e-05	192	168	6	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK3 NRCAM FAM111B MTMR7 TMEM62 EML5	8.99e-05	192	168	6	d3634574b2e8d2ded6446969361b70761b331aea
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	EXT1 JMJD1C SDK1 VPS13B PDZD2 WDR72	8.99e-05	192	168	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
Disease	Liddle syndrome (implicated_via_orthology)	NEDD4L WWP2 NEDD4	6.23e-07	4	160	3	DOID:0050477 (implicated_via_orthology)
Disease	smoking status measurement, Cannabis use, schizophrenia	WWP2 NCAM1 NTM SDK1	1.78e-05	29	160	4	EFO_0006527, EFO_0007585, MONDO_0005090
Disease	Malignant neoplasm of breast	ADAMTS19 NRCAM DYNC2H1 OBSCN H6PD ADAR RXRB PHGDH NEDD4 FASN NLRP9 ROBO1 USP54 MMP3 CTNNB1 L3MBTL3 VPS13B	7.90e-05	1074	160	17	C0006142
Disease	alcoholic liver disease	CUX2 LRFN5 ROBO1 LSAMP L3MBTL3	8.58e-05	82	160	5	EFO_0008573
Disease	left ventricular systolic function measurement	FLNC NEDD4L OBSCN GAREM1	9.55e-05	44	160	4	EFO_0008206
Disease	Mammary Neoplasms	NRCAM DYNC2H1 H6PD ADAR RXRB PHGDH TGFBR2 FASN MMP3 CTNNB1 L3MBTL3	1.51e-04	527	160	11	C1458155
Disease	hereditary multiple exostoses (implicated_via_orthology)	EXT1 EXTL3	1.74e-04	4	160	2	DOID:206 (implicated_via_orthology)
Disease	Hepatitis	GABRG3 NTM WDR72	2.23e-04	22	160	3	HP_0012115
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	CERT1 JMJD1C LIPC BCAM EPHB1	2.51e-04	103	160	5	EFO_0008595, EFO_0020944
Disease	Hypertrophic Cardiomyopathy	MYOM1 OBSCN IDH2 FASN	2.63e-04	57	160	4	C0007194
Disease	non-arteritic anterior ischemic optic neuropathy (is_implicated_in)	F5 GP1BA	2.89e-04	5	160	2	DOID:0050864 (is_implicated_in)
Disease	triglycerides to total lipids in IDL percentage	CERT1 JMJD1C LIPC BCAM	3.87e-04	63	160	4	EFO_0022329
Disease	serum gamma-glutamyl transferase measurement	CUX2 NEDD4L PCNX3 GON4L ZC3H11B JMJD1C CAMKK2 TENM4 ROBO1 MICAL3 CABIN1 L3MBTL3 EPHA1 EPHB1	4.78e-04	914	160	14	EFO_0004532
Disease	body weight	PAPPA2 GABRG3 CUX2 NRCAM GON4L OPCML ACSL3 FASN LIPC NEGR1 LRFN5 CHRDL1 LSAMP L3MBTL3 EIF2AK3 PDZD2 EPHB1	5.16e-04	1261	160	17	EFO_0004338
Disease	triglycerides to total lipids in very small VLDL percentage	CERT1 JMJD1C LIPC BCAM	5.47e-04	69	160	4	EFO_0022341
Disease	Ovarian neoplasm	OPCML CTNNB1	6.03e-04	7	160	2	cv:C0919267
Disease	centronuclear myopathy (implicated_via_orthology)	MTMR7 MTM1	6.03e-04	7	160	2	DOID:14717 (implicated_via_orthology)
Disease	Mammary Carcinoma, Human	NRCAM DYNC2H1 H6PD ADAR RXRB PHGDH FASN MMP3 CTNNB1 L3MBTL3	6.16e-04	525	160	10	C4704874
Disease	Mammary Neoplasms, Human	NRCAM DYNC2H1 H6PD ADAR RXRB PHGDH FASN MMP3 CTNNB1 L3MBTL3	6.16e-04	525	160	10	C1257931
Disease	refractive error, age at onset, Myopia	ZC3H11B GRIK1 BMP3 NTM LRFN5 L3MBTL3	6.67e-04	193	160	6	EFO_0004847, HP_0000545, MONDO_0004892
Disease	mood instability measurement	PRSS37 NCAM1 NEGR1 LSAMP EPHB1	6.81e-04	128	160	5	EFO_0008475
Disease	Breast Carcinoma	NRCAM DYNC2H1 H6PD ADAR RXRB PHGDH FASN MMP3 CTNNB1 L3MBTL3	7.43e-04	538	160	10	C0678222
Disease	age at initiation of corrective lens use	NEGR1 BRWD1	8.01e-04	8	160	2	EFO_0021781
Disease	ovarian neoplasm	MUC16 OPCML FASN CAMKK2 CTNNB1	8.38e-04	134	160	5	C0919267
Disease	Malignant neoplasm of ovary	MUC16 OPCML FASN CAMKK2 CTNNB1	9.25e-04	137	160	5	C1140680
Disease	centronuclear myopathy X-linked (implicated_via_orthology)	MTMR7 MTM1	1.03e-03	9	160	2	DOID:0111225 (implicated_via_orthology)
Disease	waist-hip ratio	PAPPA2 CUX2 DYNC2H1 WWP2 ARFGEF1 ZC3H11B NCAM1 H6PD JMJD1C OPCML COL18A1 CAMKK2 CDK5RAP3 UBE2G1 ROBO1 L3MBTL3	1.06e-03	1226	160	16	EFO_0004343
Disease	Schizophrenia	NCAM1 GRIK1 OPCML CAMKK2 TENM4 STXBP1 EML5 LSAMP MMP3 CTNNB1 C9orf72 MDGA1 KIF17	1.09e-03	883	160	13	C0036341
Disease	lung cancer (is_marker_for)	ACSL3 MMP3 CTNNB1	1.24e-03	39	160	3	DOID:1324 (is_marker_for)
Disease	membranoproliferative glomerulonephritis (implicated_via_orthology)	F5 TGFBR2	1.28e-03	10	160	2	DOID:2920 (implicated_via_orthology)
Disease	intermediate density lipoprotein measurement	CERT1 JMJD1C LIPC BCAM	1.31e-03	87	160	4	EFO_0008595
Disease	Alzheimer disease	GABRG3 MRC1 CR1 LIPC MROH1 NTM MMP3 BCAM SDK1	1.38e-03	485	160	9	MONDO_0004975
Disease	cocaine use	GRIK1 CHRNB3	1.56e-03	11	160	2	C3496069
Disease	early infantile epileptic encephalopathy (implicated_via_orthology)	CDK5RAP3 STXBP1	1.56e-03	11	160	2	DOID:0050709 (implicated_via_orthology)
Disease	Situs Inversus	ANKS6 NODAL	1.56e-03	11	160	2	C0037221
Disease	smoking status measurement	WWP2 NCAM1 GRIK1 ADAR OPCML TENM4 NEGR1 NTM LSAMP MDGA1 USH2A SDK1 BRWD1 WDR72 EPHB1	1.67e-03	1160	160	15	EFO_0006527
Disease	Neurodevelopmental Disorders	CERT1 PPP2R5D STXBP1 CTNNB1	1.67e-03	93	160	4	C1535926
Disease	concentration of large LDL particles measurement	CERT1 LIPC BCAM	1.76e-03	44	160	3	EFO_0022160
Disease	cholesterol in medium VLDL measurement	CERT1 LIPC BCAM	1.76e-03	44	160	3	EFO_0022225
Disease	Gastric Adenocarcinoma	TGFBR2 CTNNB1 EPHB1	1.88e-03	45	160	3	C0278701
Disease	unipolar depression, information processing speed, cognitive function measurement	SLC25A46 NLRP9 ROBO1	2.13e-03	47	160	3	EFO_0003761, EFO_0004363, EFO_0008354
Disease	matrix metalloproteinase measurement	DYNC2H1 MMP3	2.19e-03	13	160	2	EFO_0004744
Disease	myopathy (implicated_via_orthology)	FLNC COL18A1 MTM1	2.26e-03	48	160	3	DOID:423 (implicated_via_orthology)
Disease	Alzheimer disease, educational attainment	DOCK3 CR1 JMJD1C NEGR1 BCAM EPHA1	2.35e-03	247	160	6	EFO_0011015, MONDO_0004975
Disease	sodium measurement	CUX2 JMJD1C NEGR1 WDR72	2.43e-03	103	160	4	EFO_0009282
Disease	triglycerides to total lipids in medium LDL percentage	JMJD1C LIPC BCAM	2.54e-03	50	160	3	EFO_0022334
Disease	smoking behavior	CAMKK1 NCAM1 OPCML CHRNB3 NTM SDK1 BRWD1	2.68e-03	341	160	7	EFO_0004318
Disease	triglycerides to total lipids in large LDL percentage	JMJD1C LIPC BCAM	2.69e-03	51	160	3	EFO_0022331
Disease	susceptibility to rubella infection measurement	OPCML NEGR1 PDZD2	2.85e-03	52	160	3	EFO_0008418
Disease	thrombosis (is_implicated_in)	F5 MMP3	2.93e-03	15	160	2	DOID:0060903 (is_implicated_in)
Disease	triglycerides to total lipids in very large VLDL percentage	JMJD1C LIPC BCAM	3.00e-03	53	160	3	EFO_0022340
Disease	Familial thoracic aortic aneurysm and aortic dissection	TGFBR2 COL18A1 VCAN	3.00e-03	53	160	3	C4707243
Disease	free cholesterol in small LDL measurement	CERT1 LIPC BCAM	3.00e-03	53	160	3	EFO_0022271
Disease	free cholesterol to total lipids in small LDL percentage	JMJD1C LIPC BCAM	3.00e-03	53	160	3	EFO_0022286
Disease	cholesteryl esters to total lipids in very large VLDL percentage	JMJD1C LIPC BCAM	3.00e-03	53	160	3	EFO_0022258
Disease	Ciliopathies	DYNC2H1 CPLANE1 NODAL USH2A	3.08e-03	110	160	4	C4277690
Disease	Intellectual Disability	CUX2 GON4L CERT1 COL18A1 FASN PPP2R5D ALDH4A1 DYNC1H1	3.15e-03	447	160	8	C3714756
Disease	cholesterol to total lipids in very large VLDL percentage	JMJD1C LIPC BCAM	3.17e-03	54	160	3	EFO_0022244
Disease	interferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement	F5 JMJD1C	3.34e-03	16	160	2	EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Disease	p-cresol sulfate measurement	STARD13 GABRG3	3.34e-03	16	160	2	EFO_0010998
Disease	Cannabis use	NCAM1 SDK1	3.34e-03	16	160	2	EFO_0007585
Disease	response to acetylsalicylate	SH2D2A EPHB1	3.34e-03	16	160	2	GO_1903492
Disease	cathepsin L1 measurement	MAN2B1 C9orf72	3.34e-03	16	160	2	EFO_0010619
Disease	low density lipoprotein cholesterol measurement, lipid measurement	CERT1 LIPC BCAM BRWD1	3.50e-03	114	160	4	EFO_0004529, EFO_0004611
Disease	ovarian cancer (is_implicated_in)	MUC16 OPCML CTNNB1	3.51e-03	56	160	3	DOID:2394 (is_implicated_in)
Disease	hippocampal atrophy	F5 COL18A1 VPS13B	3.51e-03	56	160	3	EFO_0005039
Disease	Abnormality of refraction	DOCK3 GABRG3 ZC3H11B GRIK1 NEDD4 BMP3 NTM LRFN5 ROBO1 CTNNB1	3.82e-03	673	160	10	HP_0000539
Disease	urate measurement, spine bone mineral density	PAPPA2 ROBO1 LSAMP	3.88e-03	58	160	3	EFO_0004531, EFO_0007701
Disease	cholesterol in IDL measurement	JMJD1C LIPC BCAM	3.88e-03	58	160	3	EFO_0021899
Disease	aspartate aminotransferase measurement	MRC1 CUX2 NEDD4L OBSCN ERVK13-1 OPCML LIPC HMCN2 ROBO1 KIAA2012 L3MBTL3 GOT1	3.92e-03	904	160	12	EFO_0004736
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	NRCAM JMJD1C LIPC BCAM L3MBTL3 CDH15	4.05e-03	276	160	6	EFO_0004612, EFO_0020943
Disease	triglycerides to total lipids in small LDL percentage	JMJD1C LIPC BCAM	4.07e-03	59	160	3	EFO_0022337
Disease	free cholesterol to total lipids in very large VLDL percentage	JMJD1C LIPC BCAM	4.07e-03	59	160	3	EFO_0022289
Disease	sphingomyelin measurement	CERT1 JMJD1C LIPC USH2A SDK1 DYNC1H1	4.20e-03	278	160	6	EFO_0010118
Disease	blood nickel measurement	MYOM1 MUC16 F5 USH2A	4.20e-03	120	160	4	EFO_0007583
Disease	matrix metalloproteinase 12 measurement	DYNC2H1 MMP3	4.22e-03	18	160	2	EFO_0010590
Disease	glucuronate measurement	MTMR7 WDR72	4.22e-03	18	160	2	EFO_0010486
Disease	Hemangiosarcoma	COL18A1 CTNNB1	4.22e-03	18	160	2	C0018923
Disease	total lipids in IDL	JMJD1C LIPC BCAM	4.27e-03	60	160	3	EFO_0022161
Disease	cholesterol to total lipids in IDL percentage	JMJD1C LIPC BCAM	4.27e-03	60	160	3	EFO_0022233
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	CERT1 JMJD1C LIPC BCAM	4.33e-03	121	160	4	EFO_0008595, EFO_0020943
Disease	free cholesterol in IDL measurement	JMJD1C LIPC BCAM	4.47e-03	61	160	3	EFO_0022181
Disease	free cholesterol in VLDL measurement	CERT1 LIPC BCAM	4.47e-03	61	160	3	EFO_0022276
Disease	metabolic syndrome	CUX2 CERT1 JMJD1C LIPC BCAM	4.79e-03	200	160	5	EFO_0000195
Disease	puberty onset measurement	DOCK3 JMJD1C NEGR1 BRWD1	4.85e-03	125	160	4	EFO_0005677
Disease	triglycerides to total lipids in medium VLDL percentage	JMJD1C LIPC BCAM	4.90e-03	63	160	3	EFO_0022335
Disease	melanoma	DOCK3 HMCN2 ACSF3 CDH15	4.99e-03	126	160	4	EFO_0000756
Disease	Colorectal Carcinoma	FLNC NRCAM OBSCN ARFGEF1 F5 TGFBR2 UGT3A2 CTNNB1 NODAL EPHA1	5.11e-03	702	160	10	C0009402

Protein segments in the cluster

Peptide	Gene	Start	Entry
VHVSGPIFVLKWNPR	TMEM62	366	Q0P6H9
ILPGSPVKRTWHRHL	C2orf16	1516	Q68DN1
QELTPRWTPKAAHVL	FAM234A	356	Q9H0X4
WDLVVFGHERPSRKP	CHTF18	311	Q8WVB6
GKIPIRWTAPEAIAH	EPHA1	786	P21709
HSIKVPSESLWLPDI	CHRNB3	101	Q05901
PTGTVPKWDSHIRAA	BMP3	266	P12645
LTVKRTPHEAWRVPL	ERVK13-1	26	Q9NX77
SGPEHPELWRLTVAS	ERVK-18	221	O42043
SGPEHPELWRLTVAS	ERVK-9	331	Q9UKH3
HTIPLSVIPKTDWGV	VCAN	971	P13611
WKPLIHSPSRTPVLV	EIF2AK3	431	Q9NZJ5
FKTTIPHALLTWRPN	ARFGEF1	1531	Q9Y6D6
LEVPHIQTRWKHPSV	GRIK1	126	P39086
HIKLKTPGVDAPSWL	ARFIP1	356	P53367
VIVGLLKFWPKTHSP	PPP2R5D	361	Q14738
WTSPQVIKETHKPLG	ALDH4A1	541	P30038
WPHGITIVTPDRKFL	ADAP1	321	O75689
PLPVLEKWKNITGHT	ACSF3	336	Q4G176
LWHTVTLSSPLVGRP	FBXL6	156	Q8N531
SVSDLLSRPKPWHKL	CUX2	1081	O14529
PGVLKTHRLPWSRDL	NWD1	236	Q149M9
RHASPGVLVVSWLPV	RIMBP3B	1096	A6NNM3
RHASPGVLVVSWLPV	RIMBP3C	1096	A6NJZ7
WEKISAKGPTTAPLH	ADAMTS19	866	Q8TE59
EHSVLDLWRTKPPKG	IQCC	391	Q4KMZ1
VGWCKEHRRTLITPP	L3MBTL3	426	Q96JM7
PAIHWISPEGKLISN	LRFN5	316	Q96NI6
HIPTWGFNSVRLPTK	ARL10	106	Q8N8L6
QSEKVRLHWPTSLPS	CERT1	341	Q9Y5P4
LVTGHPRPQVRWTKT	MDGA1	61	Q8NFP4
TSIILEWHPPRETGG	EPHB1	336	P54762
AHLTWEPPSVTSGKI	HCFC1	1906	P51610
THELTSRVTPIPGDW	MUC16	2281	Q8WXI7
PSHWPLIKATVGLIR	CTNNB1	501	P35222
ERIGWRALVHPKTHP	MICAL3	196	Q7RTP6
VEQWGTPEKLPRAHT	NEDD4	1271	P46934
LATGKPEPSISWRHI	NEGR1	161	Q7Z3B1
GRPEPTVTWRHISPK	NTM	161	Q9P121
LAEVHWDPVPLKSIR	NRCAM	861	Q92823
SPDPRKETWILHSQI	MTMR7	41	Q9Y216
LQRHSSKPVLPTSGW	MTMR12	711	Q9C0I1
KGVPIQTPREHSWIS	HHLA3	91	Q9XRX5
RGSPPIHVSWLKDGL	HMCN2	3346	Q8NDA2
EPAPKITWHRDGIVL	HMCN2	3621	Q8NDA2
TRIGVPDIKLHPWVT	CAMKK1	396	Q8N5S9
LGLPSSKWVHPENAV	JMJD1C	876	Q15652
HIGPAIPEVSSVWFK	FAM91A1	521	Q658Y4
KLEPELHLISSFWPS	MMP3	321	P08254
SRSQKVGVAWVEPHP	PRSS22	116	Q9GZN4
VSRSPKLEVWLSHEG	PCNX3	1496	Q9H6A9
WAVVPPSHTKGSLLQ	KIAA0232	946	Q92628
DPPLSGTTHIWIRVT	PCDHGB1	216	Q9Y5G3
GWSPPRSRVSLHKED	PDZD2	1576	O15018
EIKVIPTPSADHWAL	PDE6B	326	P35913
GKDVLRHPTWPQKSV	COL18A1	1676	P39060
LWLEEGKPSHQPLTR	GAREM1	456	Q9H706
VPTKPIKHTIIISWG	FLNC	731	Q14315
NLSPVGRVTPKEWKH	COX7B2	66	Q8TF08
STPVWRPPLKHASLE	KIAA2012	456	Q0VF49
IIPWSTGPRHSGLVL	LIPC	436	P11150
SGIPNLGVWPKRIHT	METTL15P1	21	P0C7V9
VGVLIKPSWVLAPAH	PRSS37	41	A4D1T9
HLGEPPWVATIKLSG	GGN	621	Q86UU5
RSWKDSSLPPHILEV	DDX23	391	Q9BUQ8
IEHLSPWIKSPRGHE	MROH1	921	Q8NDA8
SVKVEGRPVPTVHWL	OBSCN	5391	Q5VST9
HPLRWLVRTKPTKSS	OBSCN	5636	Q5VST9
GRPEPTVTWRHLSVK	OPCML	161	Q14982
QLIVNPRGWKPSVTH	NPY6R	136	Q99463
TNKSLTIHWLPPISG	PAPPA2	856	Q9BXP8
PKDTFRLWLTAEVHP	DYNC2H1	3801	Q8NCM8
DSGKLAAPWHIPTIA	CEFIP	991	Q711Q0
PHISWKRESGIPIKE	IGSF22	96	Q8N9C0
TWIESISELHRSKPP	IFT46	181	Q9NQC8
VPGWTKPITIGRHAH	IDH2	161	P48735
EAKEPHVSSVLPWII	CABIN1	836	Q9Y6J0
HSNSPRWGEIIKLPI	DOCK3	481	Q8IZD9
QGTTPPIWHLTDKKR	ADAR	346	P55265
KHRWPATAVPVVVIE	EXT1	526	Q16394
ILSGNTAHWSTKPPI	CR1	1046	P17927
VVSPWTIPSEIHKIL	CPLANE1	3116	Q9H799
PPQVEVHVWTIRKGI	CHRDL1	371	Q9BU40
KTTSLLHPDSSRWIP	GABRG3	351	Q99928
SGPEHPELWRLTVAS	ERVK-24	221	P61566
SGPEHPELWRLTVAS	ERVK-7	221	P61567
SVSRGPLSWTHVHPK	CD19	206	P15391
SLQVSWTPPLGRVLH	COL20A1	756	Q9P218
SRSHSLLPPWVDLKE	LINC02908	101	Q6ZV77
LPRGRIPTSWVHEET	GAS2L2	411	Q8NHY3
WRDSLTLHTKPEPLE	FNDC11	296	Q9BVV2
SHITRKPPIKVTSRW	EXTL3	841	O43909
WRTGTEPSVVERPHL	CDK5RAP3	241	Q96JB5
PTFGPDSVEHWIKRV	CCDC191	31	Q8NCU4
KVWPHLALRVPAFET	FOXRED1	386	Q96CU9
HVSGKPDTQERWLPS	GON4L	2066	Q3T8J9
RLEALKTPGTWNHIT	GOT1	341	P17174
HSKVRQPWSIPVLPD	ANKS6	436	Q68DC2
FHPPVWITDTTLRKS	BRWD1	941	Q9NSI6
WVKLGSLKPHLFPVT	FLVCR2	166	Q9UPI3
SGPEHPELWRLTVAS	ERVK-21	331	P61565
VVKFPTKAHTTPWGL	GP1BA	311	P07359
PVSRWAQIHLVKTPL	MAN2B1	671	O00754
VVPEIKLHPWVTRHG	CAMKK2	436	Q96RR4
SHVRDLPPVSGSIIW	DYNC1H1	636	Q14204
PGGPVWIKETRTRHL	DALRD3	21	Q5D0E6
PSIHIWDTETIKPLS	EML5	751	Q05BV3
AAEPVTFHVPWKRLL	C9orf40	6	Q8IXQ3
SLHPPWTTIFKGERV	FCRLB	26	Q6BAA4
VGKNTHPSLWPDIIS	FAM111B	496	Q6SJ93
GTPLISPLIKWDHSL	FASN	826	P49327
TLVSRVGHEPKKWPI	H6PD	756	O95479
LLPIISWPHTTKVQG	LHFPL7	166	Q6ICI0
VHGLPTPALRWTKDS	BCAM	386	P50895
PQVTWFREGHKIIPS	SDK1	221	Q7Z5N4
AWVIPPISVSENHKR	CDH15	46	P55291
HWDKILGTLRTASVP	CH25H	256	O95992
LTPAQALRHPWISKS	DYRK3	511	O43781
LPVLLPRHFKWIIGS	HELB	221	Q8NG08
PITKISHIPPSRWAL	JADE3	296	Q92613
ILGPRVRHIWAPKTE	C9orf72	36	Q96LT7
GFWKIPHPVITKTSL	KIF17	891	Q9P2E2
TPVTFTKWLRGEPSH	MRC1	441	P22897
KGINSTTIHLRWFPP	USH2A	1476	O75445
PHPSRDFVVLRTWKT	STARD13	1006	Q9Y3M8
KVTWLAETTHALPIP	EPRS1	606	P07814
TPRVTKNEALWHPTL	TAPBPL	161	Q9BX59
TLGHPVLRKSWSRPV	SH2D2A	316	Q9NP31
GPEGKWIISSLTPKH	F5	301	P12259
PVITWRHLTPTGREF	LSAMP	161	Q13449
TRPLSKWLKHPGALE	NODAL	156	Q96S42
LWPGKVKVSVSLVHP	NXPE3	176	Q969Y0
RHASPGVLVVSWLPV	RIMBP3	1096	Q9UFD9
PGIFTDISKVLPWIH	OVCH2	281	Q7RTZ1
HLVTLLLWRPGSVTP	SIGIRR	281	Q6IA17
PLHIVLWTRIASTIP	TGFBR2	11	P37173
LWTRIASTIPPHVQK	TGFBR2	16	P37173
PIWIIIAAKHPATRT	SLC41A2	361	Q96JW4
PATRTVLHSGWEPVI	SLC41A2	371	Q96JW4
GKWEVLIGSTHILTP	STXBP1	561	P61764
VEWAKRIPHFSSLPL	RXRB	351	P28702
IDSIEHIPPARWKLT	BRPF1	371	P55201
LRHIITVDGKPPTWS	ACSL3	231	O95573
ETVTKGFVHPDPLWI	NCAPD2	851	Q15021
EEKIPHLTISHGPWI	NLRP9	966	Q7RTR0
VVSSLPPTIIWKHKG	NCAM1	141	P13591
PQWTVPLGDSRSHIK	TEX13D	441	A0A0J9YY54
HNTKTTTWERPLPPG	WWP2	321	O00308
RSGIKLSSEPHLSPW	TICRR	261	Q7Z2Z1
TFRLLVSVGHWLPKP	ZNF135	46	P52742
VSVGHWLPKPNVISL	ZNF135	51	P52742
LTPWLEFSKSGTHLP	XKRY	86	O14609
LHGVLSVWRTLPKGT	TEP1	1431	Q99973
LCWDVRTPKTPVLIH	TEP1	2086	Q99973
PVLSWIHPENKTVIV	MTM1	226	Q13496
SEFTPLPREVLHKWS	SLC25A46	181	Q96AG3
KISPEKLVEWTSPGH	SERPINB13	261	Q9UIV8
HTPSLRWDETPGRAK	SF3B1	226	O75533
TLPLWGSHLLTVVRP	TMEM214	546	Q6NUQ4
SGRITLWHIPDVPVS	WDR72	346	Q3MJ13
IQPGSTVHVLRKSWP	UBL7	81	Q96S82
PAKVWTDLRHTGFLP	NUP188	626	Q5SRE5
TQLSTHEAPGRWKPV	PRAC2	61	D3DTV9
TVLSPEHPVRLWGRS	TENM4	121	Q6N022
PAIAPIEHVLSGWKA	UTP14A	166	Q9BVJ6
SPVPTILWRKDGVLV	ROBO1	481	Q9Y6N7
LVSSHVTWGPTRKEP	PIGZ	191	Q86VD9
PVLTAVPGITWHLTK	ZC3H11B	596	A0A1B0GTU1
VPGITWHLTKQLPTK	ZC3H11B	601	A0A1B0GTU1
LTPWLEFSKSGTHLP	XKRY2	86	A2RUG3
HRGLWTLPSGKSVPV	TNK1	131	Q13470
RIHVPWTKLGSEPVV	VPS13B	66	Q7Z7G8
LVALPGHIPWRKSRS	ZNF212	411	Q9UDV6
LTSAFSPHTKPWIGL	PHGDH	321	O43175
HSVTPVEISWPLDLK	VSIG10L	831	Q86VR7
SHPLSPTQRLVGWID	UGT3A2	446	Q3SY77
KPEERWLPIHTVETI	UBE2G1	106	P62253
LVLPIVLWGRKAPTH	WDR7	6	Q9Y4E6
IHALWTDFPPSKISR	ZP2	441	Q05996
RWFPHIGLTQKTPES	TEX36	16	Q5VZQ5
VIRLWHPNISTKPVG	WDR64	346	B1ANS9
AKRSAGLVPSWRHIP	USP54	691	Q70EL1
APEFIIKPRSHTVWE	MYOM1	276	P52179
VHTTPGLPSGWEERK	NEDD4L	381	Q96PU5
TIEQWGSPEKLPRAH	NEDD4L	926	Q96PU5