Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	NFYC NFXL1 ZNF202 ZNF384 INSM2 SALL4 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 ZNF649 VEZF1 ZNF774 CASZ1 ZNF358 SNAI2	1.46e-08	1459	47	17	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	NFYC NFXL1 ZNF202 ZNF384 INSM2 SALL4 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 VEZF1 ZNF774 CASZ1 ZNF358 SNAI2	6.62e-08	1412	47	16	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NFYC ZNF202 ZNF384 INSM2 SALL4 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 ZNF649 ZNF774 ZNF358 SNAI2	6.04e-07	1244	47	14	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	NFYC ZNF202 ZNF384 INSM2 SALL4 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 ZNF649 ZNF774 ZNF358 SNAI2	7.81e-07	1271	47	14	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	NFYC ZNF384 ZNF836 ZNF467 VEZF1 CASZ1 ZNF358	3.12e-04	560	47	7	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	NFYC ZNF384 ZNF836 ZNF467 VEZF1 CASZ1 ZNF358	3.33e-04	566	47	7	GO:0001216
GeneOntologyBiologicalProcess	vitamin D metabolic process	LRP2 SNAI1 SNAI2	1.90e-05	23	47	3	GO:0042359
GeneOntologyBiologicalProcess	negative regulation of vitamin D biosynthetic process	SNAI1 SNAI2	5.06e-05	5	47	2	GO:0010957
GeneOntologyCellularComponent	microfibril	ADAMTS10 FBN1	3.80e-04	13	47	2	GO:0001527
HumanPheno	Spinal canal stenosis	ADAMTS10 PHF6 FBN1 CASZ1	5.62e-06	43	15	4	HP:0003416
HumanPheno	Broad skull	ADAMTS10 FBN1	2.42e-05	3	15	2	HP:0002682
HumanPheno	Microspherophakia	ADAMTS10 FBN1	4.84e-05	4	15	2	HP:0030961
HumanPheno	Spherophakia	ADAMTS10 FBN1	8.05e-05	5	15	2	HP:0034375
HumanPheno	Hypoplasia of the iris	LRP2 SALL4 FBN1	1.28e-04	35	15	3	HP:0007676
MousePheno	abnormal neural tube closure	LRP2 SALL4 CELSR1 BRD1 GAS2L2 GEN1 SNAI2	3.50e-05	378	35	7	MP:0003720
MousePheno	delayed neural tube closure	LRP2 CELSR1 GEN1	6.16e-05	31	35	3	MP:0002621
Domain	Znf_C2H2-like	ZNF202 ZNF384 INSM2 SALL4 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 ZNF649 VEZF1 ZNF774 CASZ1 ZNF358 RNF138 SNAI2	4.45e-11	796	47	16	IPR015880
Domain	Znf_C2H2	ZNF202 ZNF384 INSM2 SALL4 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 ZNF649 VEZF1 ZNF774 CASZ1 ZNF358 RNF138 SNAI2	5.26e-11	805	47	16	IPR007087
Domain	ZnF_C2H2	ZNF202 ZNF384 INSM2 SALL4 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 ZNF649 VEZF1 ZNF774 CASZ1 ZNF358 RNF138 SNAI2	5.55e-11	808	47	16	SM00355
Domain	zf-C2H2	ZNF202 ZNF384 INSM2 SALL4 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 ZNF649 VEZF1 ZNF774 CASZ1 ZNF358 SNAI2	7.46e-11	693	47	15	PF00096
Domain	ZINC_FINGER_C2H2_2	ZNF202 ZNF384 INSM2 SALL4 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 ZNF649 VEZF1 ZNF774 CASZ1 ZNF358 SNAI2	3.54e-10	775	47	15	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF202 ZNF384 INSM2 SALL4 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 ZNF649 VEZF1 ZNF774 CASZ1 ZNF358 SNAI2	3.67e-10	777	47	15	PS00028
Domain	-	ZNF202 ZNF384 INSM2 SALL4 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 ZNF649 VEZF1 ZNF774 ZNF358 SNAI2	6.94e-10	679	47	14	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF202 ZNF384 INSM2 SALL4 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 ZNF649 VEZF1 ZNF774 ZNF358 SNAI2	9.21e-10	694	47	14	IPR013087
Domain	zf-C2H2_6	ZNF384 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 ZNF649 ZNF358 SNAI2	7.44e-08	314	47	9	PF13912
Domain	EGF_CA	LRP2 CELSR1 FBN1 AGRN	2.49e-04	122	47	4	SM00179
Domain	KRAB	ZNF202 ZNF836 ZNF84 ZNF26 ZNF649 ZNF774	2.63e-04	358	47	6	PS50805
Domain	EGF-like_Ca-bd_dom	LRP2 CELSR1 FBN1 AGRN	2.65e-04	124	47	4	IPR001881
Domain	EGF	LRP2 CELSR1 NRG3 AGRN	2.81e-04	126	47	4	PF00008
Domain	EGF_3	LRP2 CELSR1 FBN1 NRG3 AGRN	3.01e-04	235	47	5	PS50026
Domain	EGF	LRP2 CELSR1 FBN1 NRG3 AGRN	3.01e-04	235	47	5	SM00181
Domain	EGF-like_dom	LRP2 CELSR1 FBN1 NRG3 AGRN	3.93e-04	249	47	5	IPR000742
Domain	EGF_1	LRP2 CELSR1 FBN1 NRG3 AGRN	4.38e-04	255	47	5	PS00022
Domain	EGF-like_CS	LRP2 CELSR1 FBN1 NRG3 AGRN	4.87e-04	261	47	5	IPR013032
Domain	EGF_2	LRP2 CELSR1 FBN1 NRG3 AGRN	5.22e-04	265	47	5	PS01186
Domain	Zinc_finger_PHD-type_CS	NFXL1 TRIM66 BRD1	5.85e-04	65	47	3	IPR019786
Domain	EPHD	PHF6 BRD1	1.39e-03	22	47	2	PS51805
Domain	PHD	PHF6 TRIM66 BRD1	1.46e-03	89	47	3	SM00249
Domain	Znf_PHD	PHF6 TRIM66 BRD1	1.55e-03	91	47	3	IPR001965
Domain	ZF_PHD_2	PHF6 TRIM66 BRD1	1.76e-03	95	47	3	PS50016
Domain	ZF_PHD_1	PHF6 TRIM66 BRD1	1.81e-03	96	47	3	PS01359
Domain	cEGF	LRP2 FBN1	1.94e-03	26	47	2	IPR026823
Domain	cEGF	LRP2 FBN1	1.94e-03	26	47	2	PF12662
Domain	KRAB	ZNF202 ZNF836 ZNF84 ZNF26 ZNF649	1.99e-03	358	47	5	PF01352
Domain	ASX_HYDROXYL	LRP2 CELSR1 FBN1	2.04e-03	100	47	3	PS00010
Domain	KRAB	ZNF202 ZNF836 ZNF84 ZNF26 ZNF649	2.27e-03	369	47	5	SM00349
Domain	KRAB	ZNF202 ZNF836 ZNF84 ZNF26 ZNF649	2.30e-03	370	47	5	IPR001909
Domain	EGF-type_Asp/Asn_hydroxyl_site	LRP2 CELSR1 FBN1	2.40e-03	106	47	3	IPR000152
Domain	EGF_LAM_2	CELSR1 AGRN	2.58e-03	30	47	2	PS50027
Domain	EGF_LAM_1	CELSR1 AGRN	2.58e-03	30	47	2	PS01248
Domain	Laminin_EGF	CELSR1 AGRN	3.50e-03	35	47	2	PF00053
Domain	EGF_Lam	CELSR1 AGRN	3.50e-03	35	47	2	SM00180
Domain	GPS	CELSR1 PKD1L1	3.70e-03	36	47	2	PS50221
Domain	Kazal_2	AGRN SLCO2A1	3.70e-03	36	47	2	PF07648
Domain	GPS	CELSR1 PKD1L1	3.90e-03	37	47	2	IPR000203
Domain	BROMODOMAIN_1	TRIM66 BRD1	3.90e-03	37	47	2	PS00633
Domain	LAM_G_DOMAIN	CELSR1 AGRN	4.11e-03	38	47	2	PS50025
Domain	Laminin_EGF	CELSR1 AGRN	4.11e-03	38	47	2	IPR002049
Domain	Bromodomain	TRIM66 BRD1	4.11e-03	38	47	2	PF00439
Domain	-	ZC3H3 MBNL1	4.55e-03	40	47	2	4.10.1000.10
Domain	BROMODOMAIN_2	TRIM66 BRD1	4.77e-03	41	47	2	PS50014
Domain	BROMO	TRIM66 BRD1	5.01e-03	42	47	2	SM00297
Domain	Bromodomain	TRIM66 BRD1	5.01e-03	42	47	2	IPR001487
Domain	-	TRIM66 BRD1	5.01e-03	42	47	2	1.20.920.10
Domain	LamG	CELSR1 AGRN	5.48e-03	44	47	2	SM00282
Domain	KAZAL	AGRN SLCO2A1	5.98e-03	46	47	2	SM00280
Domain	ZnF_C3H1	ZC3H3 MBNL1	6.49e-03	48	47	2	SM00356
Domain	zf-CCCH	ZC3H3 MBNL1	6.76e-03	49	47	2	PF00642
Domain	KAZAL_2	AGRN SLCO2A1	7.03e-03	50	47	2	PS51465
Domain	Growth_fac_rcpt_	LRP2 CELSR1 FBN1	7.08e-03	156	47	3	IPR009030
Domain	Kazal_dom	AGRN SLCO2A1	7.31e-03	51	47	2	IPR002350
Domain	Laminin_G	CELSR1 AGRN	9.37e-03	58	47	2	IPR001791
Domain	Znf_CCCH	ZC3H3 MBNL1	9.37e-03	58	47	2	IPR000571
Domain	ZF_C3H1	ZC3H3 MBNL1	9.37e-03	58	47	2	PS50103
Domain	Retrov_capsid_C	ADAMTS10 ZNF202	9.68e-03	59	47	2	IPR008916
Pubmed	Identification of a novel member of the snail/Gfi-1 repressor family, mlt 1, which is methylated and silenced in liver tumors of SV40 T antigen transgenic mice.	INSM2 SNAI1 SNAI2	1.93e-07	9	47	3	11221845
Pubmed	SNAIL Transctiption factor in prostate cancer cells promotes neurite outgrowth.	SNAI1 SNAI2	1.79e-06	2	47	2	33132158
Pubmed	Identification and analysis of two snail genes in the pufferfish (Fugu rubripes) and mapping of human SNA to 20q.	SNAI1 SNAI2	1.79e-06	2	47	2	10773451
Pubmed	Tumor-induced upregulation of Twist, Snail, and Slug represses the activity of the human VE-cadherin promoter.	SNAI1 SNAI2	1.79e-06	2	47	2	19046938
Pubmed	ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts.	ADAMTS10 FBN1	1.79e-06	2	47	2	21402694
Pubmed	Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress.	SNAI1 SNAI2	1.79e-06	2	47	2	15314165
Pubmed	Muscleblind‑like 1 destabilizes Snail mRNA and suppresses the metastasis of colorectal cancer cells via the Snail/E‑cadherin axis.	SNAI1 MBNL1	1.79e-06	2	47	2	30664186
Pubmed	Impact of Selected Signaling Proteins on SNAIL 1 and SNAIL 2 Expression in Ovarian Cancer Cell Lines in Relation to Cells' Cisplatin Resistance and EMT Markers Level.	SNAI1 SNAI2	1.79e-06	2	47	2	33478150
Pubmed	Conserved and divergent roles for members of the Snail family of transcription factors in the chick and mouse embryo.	SNAI1 SNAI2	1.79e-06	2	47	2	9671584
Pubmed	SNAI1 and SNAI2 are asymmetrically expressed at the 2-cell stage and become segregated to the TE in the mouse blastocyst.	SNAI1 SNAI2	1.79e-06	2	47	2	20046880
Pubmed	Snail and Slug, key regulators of TGF-β-induced EMT, are sufficient for the induction of single-cell invasion.	SNAI1 SNAI2	1.79e-06	2	47	2	23618854
Pubmed	Slug and Snail have differential effects in directing colonic epithelial wound healing and partially mediate the restitutive effects of butyrate.	SNAI1 SNAI2	1.79e-06	2	47	2	31393789
Pubmed	Snail is an independent prognostic predictor for progression and patient survival of gastric cancer.	SNAI1 SNAI2	1.79e-06	2	47	2	22471696
Pubmed	Distinct EMT programs control normal mammary stem cells and tumour-initiating cells.	SNAI1 SNAI2	1.79e-06	2	47	2	26331542
Pubmed	Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice.	SNAI1 SNAI2	1.79e-06	2	47	2	38451818
Pubmed	Expression and localization of transcription factors SNAIL and SLUG in mouse ovaries and pre-implantation embryos.	SNAI1 SNAI2	1.79e-06	2	47	2	25092544
Pubmed	'Snail factors in testicular germ cell tumours and their regulation by the BMP4 signalling pathway'.	SNAI1 SNAI2	1.79e-06	2	47	2	32441446
Pubmed	The SNAI1 and SNAI2 proteins occupy their own and each other's promoter during chondrogenesis.	SNAI1 SNAI2	1.79e-06	2	47	2	23665016
Pubmed	Modularity and reshuffling of Snail and Slug expression during vertebrate evolution.	SNAI1 SNAI2	1.79e-06	2	47	2	12482931
Pubmed	Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer.	SNAI1 SNAI2	1.79e-06	2	47	2	19502595
Pubmed	[SNAI1 and SNAI2 - transcriptional master-regulators of epithelial-mesenchimal transition].	SNAI1 SNAI2	1.79e-06	2	47	2	26571812
Pubmed	Snail family transcription factors are implicated in thyroid carcinogenesis.	SNAI1 SNAI2	1.79e-06	2	47	2	17724139
Pubmed	The transcriptional repressor Snail promotes mammary tumor recurrence.	SNAI1 SNAI2	1.79e-06	2	47	2	16169465
Pubmed	Resistomycin attenuates triple-negative breast cancer progression by inhibiting E3 ligase Pellino-1 and inducing SNAIL/SLUG degradation.	PELI1 SNAI2	1.79e-06	2	47	2	32728028
Pubmed	Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines.	SNAI1 SNAI2	1.79e-06	2	47	2	18408755
Pubmed	Expression of Snail and Slug in renal cell carcinoma: E-cadherin repressor Snail is associated with cancer invasion and prognosis.	SNAI1 SNAI2	1.79e-06	2	47	2	21808237
Pubmed	Downregulation of miR-95 in gastric cancer promotes EMT via regulation of Slug, thereby promoting migration and invasion.	SNAI1 SNAI2	5.36e-06	3	47	2	30535480
Pubmed	The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer.	SNAI1 SNAI2	5.36e-06	3	47	2	22028892
Pubmed	The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression.	SNAI1 SNAI2	5.36e-06	3	47	2	10655586
Pubmed	Snail promotes lymph node metastasis and Twist enhances tumor deposit formation through epithelial-mesenchymal transition in colorectal cancer.	SNAI1 SNAI2	5.36e-06	3	47	2	22974478
Pubmed	SNAI1 recruits HDAC1 to suppress SNAI2 transcription during epithelial to mesenchymal transition.	SNAI1 SNAI2	5.36e-06	3	47	2	31165775
Pubmed	The transcription factors Slug (SNAI2) and Snail (SNAI1) regulate phospholipase D (PLD) promoter in opposite ways towards cancer cell invasion.	SNAI1 SNAI2	5.36e-06	3	47	2	26781944
Pubmed	Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinoma.	SNAI1 SNAI2	5.36e-06	3	47	2	20150431
Pubmed	The SLUG zinc-finger protein represses E-cadherin in breast cancer.	SNAI1 SNAI2	5.36e-06	3	47	2	11912130
Pubmed	CCL2 expression correlates with Snail expression and affects the prognosis of patients with gastric cancer.	SNAI1 SNAI2	5.36e-06	3	47	2	28215642
Pubmed	Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition.	SNAI1 SNAI2	5.36e-06	3	47	2	17018611
Pubmed	Immunohistochemical study of correlation between histologic subtype and expression of epithelial-mesenchymal transition-related proteins in synovial sarcomas.	SNAI1 SNAI2	5.36e-06	3	47	2	21809991
Pubmed	Helicobacter pylori-induced epithelial-mesenchymal transition, a potential role of gastric cancer initiation and an emergence of stem cells.	SNAI1 SNAI2	5.36e-06	3	47	2	25784376
Pubmed	Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.	ADAMTS10 FBN1	5.36e-06	3	47	2	30201140
Pubmed	The transcription factors Snail1 and Snail2 repress vitamin D receptor during colon cancer progression.	SNAI1 SNAI2	5.36e-06	3	47	2	20138990
Pubmed	The snail superfamily of zinc-finger transcription factors.	SNAI1 SNAI2	5.36e-06	3	47	2	11994736
Pubmed	Snail family members unequally trigger EMT and thereby differ in their ability to promote the neoplastic transformation of mammary epithelial cells.	SNAI1 SNAI2	5.36e-06	3	47	2	24638100
Pubmed	Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma.	SNAI1 SNAI2	5.36e-06	3	47	2	19821482
Pubmed	TOX3 inhibits cancer cell migration and invasion via transcriptional regulation of SNAI1 and SNAI2 in clear cell renal cell carcinoma.	SNAI1 SNAI2	5.36e-06	3	47	2	30772441
Pubmed	Differential role of Snail1 and Snail2 zinc fingers in E-cadherin repression and epithelial to mesenchymal transition.	SNAI1 SNAI2	5.36e-06	3	47	2	24297167
Pubmed	Quercetin modulates Wnt signaling components in prostate cancer cell line by inhibiting cell viability, migration, and metastases.	SNAI1 SNAI2	5.36e-06	3	47	2	27495232
Pubmed	HOPX hypermethylation promotes metastasis via activating SNAIL transcription in nasopharyngeal carcinoma.	SNAI1 SNAI2	5.36e-06	3	47	2	28146149
Pubmed	Proteomic Analysis of Epithelial to Mesenchymal Transition (EMT) Reveals Cross-talk between SNAIL and HDAC1 Proteins in Breast Cancer Cells.	SNAI1 SNAI2	5.36e-06	3	47	2	26764010
Pubmed	ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.	SNAI1 FBN1 SNAI2	9.15e-06	30	47	3	32882513
Pubmed	VAV1 represses E-cadherin expression through the transactivation of Snail and Slug: a potential mechanism for aberrant epithelial to mesenchymal transition in human epithelial ovarian cancer.	SNAI1 SNAI2	1.07e-05	4	47	2	23856093
Pubmed	MiR-22 suppresses epithelial-mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loop.	SNAI1 SNAI2	1.07e-05	4	47	2	29434190
Pubmed	Modulation of beta-catenin and E-cadherin interaction by Vpu increases human immunodeficiency virus type 1 particle release.	SNAI1 SNAI2	1.07e-05	4	47	2	18256147
Pubmed	Transcription factors Snail, Slug, Twist, and SIP1 in spindle cell carcinoma of the head and neck.	SNAI1 SNAI2	1.07e-05	4	47	2	19381684
Pubmed	Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis.	SNAI1 SNAI2	1.07e-05	4	47	2	21610693
Pubmed	Expression of the E-cadherin repressors Snail, Slug and Zeb1 in urothelial carcinoma of the urinary bladder: relation to stromal fibroblast activation and invasive behaviour of carcinoma cells.	SNAI1 SNAI2	1.07e-05	4	47	2	22820858
Pubmed	Differential expression of the epithelial mesenchymal transition factors Snail, Slug, Twist, TGF-β, and E-cadherin in ameloblastoma.	SNAI1 SNAI2	1.07e-05	4	47	2	27995335
Pubmed	Weill-Marchesani Syndrome	ADAMTS10 FBN1	1.07e-05	4	47	2	20301293
Pubmed	Differences in the expression of epithelial-mesenchymal transition related molecules between primary tumors and pulmonary metastatic tumors in colorectal cancer.	SNAI1 SNAI2	1.07e-05	4	47	2	23052737
Pubmed	Snail/Slug-YAP/TAZ complexes cooperatively regulate mesenchymal stem cell function and bone formation.	SNAI1 SNAI2	1.07e-05	4	47	2	28112996
Pubmed	Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney.	SNAI1 SNAI2	1.07e-05	4	47	2	17093497
Pubmed	HR+HER2- breast cancers with growth factor receptor-mediated EMT have a poor prognosis and lapatinib downregulates EMT in MCF-7 cells.	SNAI1 SNAI2	1.07e-05	4	47	2	28349782
Pubmed	p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma.	SNAI1 SNAI2	1.78e-05	5	47	2	20385133
Pubmed	Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis.	SNAI1 SNAI2	1.78e-05	5	47	2	22771117
Pubmed	Enhanced epithelial to mesenchymal transition (EMT) and upregulated MYC in ectopic lesions contribute independently to endometriosis.	SNAI1 SNAI2	1.78e-05	5	47	2	26198055
Pubmed	A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming.	SNAI1 SNAI2	1.78e-05	5	47	2	25240402
Pubmed	Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition.	SNAI1 SNAI2	1.78e-05	5	47	2	29074488
Pubmed	Snail/Slug binding interactions with YAP/TAZ control skeletal stem cell self-renewal and differentiation.	SNAI1 SNAI2	1.78e-05	5	47	2	27479603
Pubmed	In vitro treatment of carcinoma cell lines with pancreatic (pro)enzymes suppresses the EMT programme and promotes cell differentiation.	SNAI1 SNAI2	1.78e-05	5	47	2	23677639
Pubmed	Down-regulation of microRNAs of the miR-200 family and up-regulation of Snail and Slug in inflammatory bowel diseases - hallmark of epithelial-mesenchymal transition.	SNAI1 SNAI2	1.78e-05	5	47	2	27113480
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	ZNF202 ZNF384 INSM2 SALL4 SNAI1 BRD1 ZNF467 ECD	2.08e-05	877	47	8	20211142
Pubmed	A census of human transcription factors: function, expression and evolution.	NFYC NFXL1 ZNF202 ZNF384 ZNF26 SNAI1 ZC3H3 SNAI2	2.67e-05	908	47	8	19274049
Pubmed	NOTCH1 missense alleles associated with left ventricular outflow tract defects exhibit impaired receptor processing and defective EMT.	SNAI1 SNAI2	2.67e-05	6	47	2	20951801
Pubmed	Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex.	SNAI1 SNAI2	2.67e-05	6	47	2	14673164
Pubmed	Downregulation of E-cadherin is an essential event in activating beta-catenin/Tcf-dependent transcription and expression of its target genes in Pdcd4 knockdown cells.	SNAI1 SNAI2	2.67e-05	6	47	2	19784072
Pubmed	Hypoxia induced the differentiation of Tbx18-positive epicardial cells to CoSMCs.	SNAI1 SNAI2	2.67e-05	6	47	2	27456656
Pubmed	E-cadherin inhibits cell surface localization of the pro-migratory 5T4 oncofetal antigen in mouse embryonic stem cells.	SNAI1 SNAI2	2.67e-05	6	47	2	17507657
Pubmed	Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3.	SNAI1 SNAI2	2.67e-05	6	47	2	18799618
Pubmed	SLUG: a new target of lymphoid enhancer factor-1 in human osteoblasts.	SNAI1 SNAI2	2.67e-05	6	47	2	20128911
Pubmed	Ajuba LIM proteins are snail/slug corepressors required for neural crest development in Xenopus.	SNAI1 SNAI2	2.67e-05	6	47	2	18331720
Pubmed	Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium.	SNAI1 SNAI2	3.74e-05	7	47	2	25759216
Pubmed	Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression.	SNAI1 SNAI2	3.74e-05	7	47	2	23011797
Pubmed	Loss of function of BRCA1 promotes EMT in mammary tumors through activation of TGFβR2 signaling pathway.	SNAI1 SNAI2	4.98e-05	8	47	2	35236825
Pubmed	Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors.	SNAI1 SNAI2	4.98e-05	8	47	2	25460509
Pubmed	Expression and distribution of the zinc finger protein, SNAI3, in mouse ovaries and pre-implantation embryos.	SNAI1 SNAI2	4.98e-05	8	47	2	29445069
Pubmed	Keratinocyte Growth Factor Stimulates Growth of p75+ Neural Crest Lineage Cells During Middle Ear Cholesteatoma Formation in Mice.	SNAI1 SNAI2	4.98e-05	8	47	2	36210210
Pubmed	Molecular mechanisms of cleft lip formation in CL/Fr mice.	SNAI1 SNAI2	4.98e-05	8	47	2	18830900
Pubmed	Slug is a direct Notch target required for initiation of cardiac cushion cellularization.	SNAI1 SNAI2	4.98e-05	8	47	2	18663143
Pubmed	FBXO11 promotes ubiquitination of the Snail family of transcription factors in cancer progression and epidermal development.	SNAI1 SNAI2	6.40e-05	9	47	2	25827072
Pubmed	The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs.	SNAI1 SNAI2	6.40e-05	9	47	2	21849546
Pubmed	WT1 regulates epicardial epithelial to mesenchymal transition through β-catenin and retinoic acid signaling pathways.	SNAI1 SNAI2	7.99e-05	10	47	2	21663736
Pubmed	Retinoic acid signaling promotes the cytoskeletal rearrangement of embryonic epicardial cells.	SNAI1 SNAI2	7.99e-05	10	47	2	29447006
Pubmed	Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization.	SNAI1 SNAI2	7.99e-05	10	47	2	25893292
Pubmed	Oscillations of the snail genes in the presomitic mesoderm coordinate segmental patterning and morphogenesis in vertebrate somitogenesis.	SNAI1 SNAI2	7.99e-05	10	47	2	16516838
Pubmed	Multiple functions of Snail family genes during palate development in mice.	SNAI1 SNAI2	7.99e-05	10	47	2	17376812
Pubmed	Face morphogenesis is promoted by Pbx-dependent EMT via regulation of Snail1 during frontonasal prominence fusion.	SNAI1 SNAI2	9.75e-05	11	47	2	29437830
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	NFYC ZNF202 SALL4 ZNF836 SNAI1 VEZF1 MBNL1	9.97e-05	808	47	7	20412781
Pubmed	Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production.	NFYC PELI1	1.17e-04	12	47	2	19734906
Pubmed	Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development.	SNAI1 SNAI2	1.17e-04	12	47	2	21287656
Pubmed	miRNAs control tracheal chondrocyte differentiation.	SNAI1 SNAI2	1.17e-04	12	47	2	21945074
Pubmed	Epithelial-to-mesenchymal transition in epicardium is independent of Snail1.	SNAI1 SNAI2	1.17e-04	12	47	2	23097346
Cytoband	20q13.2	SALL4 SNAI1	3.54e-04	27	47	2	20q13.2
Cytoband	12q24.33	ZNF84 ZNF26	1.12e-03	48	47	2	12q24.33
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF202 ZNF384 INSM2 SALL4 ZNF836 ZNF84 ZNF26 SNAI1 ZNF467 ZNF649 VEZF1 ZNF774 CASZ1 ZNF358 SNAI2	2.52e-13	718	32	15	28
GeneFamily	Zinc fingers C2H2-type\|SNAG transcriptional repressors	INSM2 SNAI1 SNAI2	5.99e-07	10	32	3	1259
GeneFamily	PHD finger proteins	PHF6 TRIM66 BRD1	5.33e-04	90	32	3	88
GeneFamily	Zinc fingers CCCH-type	ZC3H3 MBNL1	1.74e-03	35	32	2	73
ToppCell	mild-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ADAMTS10 ZNF202 PELI1 CERK SNAI1 L3MBTL1	5.68e-08	195	47	6	1e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNAI1 VEGFD SLCO2A1 PKD1L1 SNAI2	1.13e-06	175	47	5	90302e8a44858ef3b2a165b88284d4788d591a99
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-Venous_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PLK2 FBN1 NRG3 AGRN SLCO2A1	2.12e-06	199	47	5	70e05d7c0c68c28754ce0e72434b205aed6287ae
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-\|Striatum / BrainAtlas - Mouse McCarroll V32	SNAI1 FBN1 VEGFD SNAI2	1.21e-05	134	47	4	a3547a68012d879d4dfe80394eace70808722e43
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)\|Striatum / BrainAtlas - Mouse McCarroll V32	SNAI1 FBN1 VEGFD SNAI2	1.21e-05	134	47	4	9458e2d0dbc18d9025b66b59f3ecc2fbc5384940
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF2BP2 CELSR1 INAVA AGRN	2.95e-05	168	47	4	ca65321259711321c175ede67bd67a47aad81d7a
ToppCell	Mild/Remission-B_naive-4\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	IRF2BP2 PELI1 INSM2 MBNL1	3.02e-05	169	47	4	c3a6179a64589a370108fea809b157839347759c
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D175\|Adult / Lineage, Cell type, age group and donor	ADAMTS10 PLK2 NRG3 SLCO2A1	3.02e-05	169	47	4	e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PRR14L FBN1 VEGFD SNAI2	3.09e-05	170	47	4	7fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	INAVA SNAI1 AGRN SLCO2A1	3.39e-05	174	47	4	e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	INAVA SNAI1 AGRN SLCO2A1	3.54e-05	176	47	4	bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-8\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLK2 ZNF84 GUCD1 ZNF649	3.62e-05	177	47	4	066e7500e7bdde88a7914f50a4661d8adf6db925
ToppCell	mild-B_cell\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZNF202 CERK SNAI1 L3MBTL1	4.12e-05	183	47	4	175aaf8fbbff52eab87d78a49d5ab02cd489c438
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	SNAI1 FBN1 VEGFD SNAI2	4.58e-05	188	47	4	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	E18.5-samps-Mesenchymal\|E18.5-samps / Age Group, Lineage, Cell class and subclass	SNAI1 FBN1 VEGFD SNAI2	4.67e-05	189	47	4	0c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SNAI1 FBN1 VEGFD SNAI2	4.87e-05	191	47	4	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	facs-Skin-Anagen-3m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 CELSR1 VEGFD SLCO2A1	4.97e-05	192	47	4	ec1fd2fb6e71f87189d66261909a84e2be63cacb
ToppCell	PND07\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLK2 FBN1 VEGFD SNAI2	4.97e-05	192	47	4	8171a60df481195c39a7f740effcae8e4deb6ca7
ToppCell	E15.5-Mesenchymal\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SNAI1 FBN1 VEGFD SNAI2	5.07e-05	193	47	4	22a9f5b61f197757f72840b9cb849cdb20430e72
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNAI1 FBN1 VEGFD SNAI2	5.07e-05	193	47	4	4c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNAI1 FBN1 VEGFD SNAI2	5.07e-05	193	47	4	ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SNAI1 FBN1 VEGFD SNAI2	5.07e-05	193	47	4	b637e1c47a98009e7d19a6daac78f888fd12748f
ToppCell	facs-Trachea-nan-3m-Epithelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 CELSR1 INAVA CASZ1	5.17e-05	194	47	4	3701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCell	facs-Trachea-nan-3m-Epithelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 CELSR1 INAVA CASZ1	5.17e-05	194	47	4	65f9bf126be26114c2c3f4c46d48318986212a92
ToppCell	PND01-03-samps-Mesenchymal\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SNAI1 FBN1 VEGFD SNAI2	5.17e-05	194	47	4	4f9bd0ded0dde1df885850714f29e73e992539a5
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLK2 AGRN CASZ1 SLCO2A1	5.17e-05	194	47	4	92a8e6e3e3f6fd9dacb723b58e7a8b63473e403e
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNAI1 FBN1 VEGFD SNAI2	5.38e-05	196	47	4	db64ab27374f82553ee577aec056141170f3656f
ToppCell	E17.5-Mesenchymal\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SNAI1 FBN1 VEGFD SNAI2	5.38e-05	196	47	4	b4ee991445b612506372b9361ebfe72cb59b811e
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SNAI1 FBN1 VEGFD SNAI2	5.38e-05	196	47	4	028a06ed92f1c058dcbeacd335625bf529e87a7b
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNAI1 FBN1 VEGFD SNAI2	5.38e-05	196	47	4	97e26622d9582b092c18ff5b7e957818f99d9631
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNAI1 FBN1 VEGFD SNAI2	5.38e-05	196	47	4	617103f4a09e009fe96c28eb5e40505a4fd6dcf4
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNAI1 FBN1 VEGFD SNAI2	5.38e-05	196	47	4	f429f045ba45e24717963315832150b12a115bfa
ToppCell	E18.5-Mesenchymal\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNAI1 FBN1 VEGFD SNAI2	5.60e-05	198	47	4	a16aa41eab2e297e56de43c22c355df0f79315da
ToppCell	E16.5-Mesenchymal\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNAI1 FBN1 VEGFD SNAI2	5.71e-05	199	47	4	ebd9ca151434f5ca27a82d4f1815a1ea500c1989
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNAI1 FBN1 VEGFD SNAI2	5.71e-05	199	47	4	9e87b64e16d595701c3beb07aa835afe3330bd10
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNAI1 FBN1 VEGFD SNAI2	5.71e-05	199	47	4	2cec0e370ee9bb3c88a7acb5519e9ea8ddb399bc
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PLK2 FBN1 SLCO2A1 MBNL1	5.82e-05	200	47	4	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocye.Tnr.Pdgfa_(Pdgfa)\|Striatum / BrainAtlas - Mouse McCarroll V32	PELI1 INAVA PKD1L1	1.52e-04	98	47	3	26250ea4171a0557a67505839cf79d3fe4d9d41a
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr\|Striatum / BrainAtlas - Mouse McCarroll V32	PELI1 INAVA PKD1L1	1.52e-04	98	47	3	42875d16ae9fcbaf988cd71be82568f2f862f2dd
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_2\|Striatum / BrainAtlas - Mouse McCarroll V32	PELI1 INAVA PKD1L1	1.52e-04	98	47	3	7a62a77ca83153dacff4d02d6e32104227d0980d
ToppCell	mLN-Dendritic_cell-cDC1\|Dendritic_cell / Region, Cell class and subclass	ZNF467 ZNF358 SLCO2A1	1.61e-04	100	47	3	c560326f6ae5338aecdf11ef8adf04bc8769745c
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SALL4 ZC3H3 UNC5CL	3.25e-04	127	47	3	353484362448f27e8377447d0c26391b1da7acc5
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular\|TCGA-Stomach / Sample_Type by Project: Shred V9	ZC3H3 GEN1 ZNF774	4.15e-04	138	47	3	93497c0a5d5e54006653b2dedc7a7041e1a613e6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLK2 NRG3 SLCO2A1	4.89e-04	146	47	3	281144e293e8c93a425c2606d2188cb2838e667f
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3\|E16.5-samps / Age Group, Lineage, Cell class and subclass	WDR90 VEGFD SNAI2	5.19e-04	149	47	3	651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SNAI1 EFNA3 ZNF467	5.39e-04	151	47	3	7b50425d2bbd7b6ff2a6e67d3e2470a4455740e0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CERK PLK2 ZNF358	5.60e-04	153	47	3	ee6f4770c6e35d59bdeec5b0ecb10119fa8c3ca5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CERK PLK2 ZNF358	5.60e-04	153	47	3	90cd6efda83c0b4b80eae2c90e7ff45dfd936dc2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CERK PLK2 ZNF358	5.60e-04	153	47	3	a35149a0c8b4ec9ad27cc4b3d34fba3b8714a6a2
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	ZNF774 CASZ1 MBNL1	5.60e-04	153	47	3	ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NRG3 SLCO2A1 SNAI2	5.82e-04	155	47	3	5d157478669b609e1f0f0a75afd0112571fc2c46
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|lymph-node_spleen / Manually curated celltypes from each tissue	GUCD1 ZNF649 GEN1	5.82e-04	155	47	3	b0e456c4915076e1d38282e116a6eb3230ae80dc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 EFNA3 NRG3	6.15e-04	158	47	3	e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 EFNA3 NRG3	6.15e-04	158	47	3	d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	SNAI1 VEGFD SNAI2	6.27e-04	159	47	3	b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCell	Control-Endothelial_cells-Inflamed_endothelial_cells\|Control / group, cell type (main and fine annotations)	PLK2 SLCO2A1 PKD1L1	6.38e-04	160	47	3	958256e3d3836160763b82bb48f794087918d935
ToppCell	BAL-Mild-cDC_5\|Mild / Compartment, Disease Groups and Clusters	ADAMTS10 FBN1 UNC5CL	6.50e-04	161	47	3	7a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP2 INSM2 GAS2L2	6.85e-04	164	47	3	cdb8cd2d6b369189ea77e4946738e2816d502e03
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP2 INSM2 GAS2L2	6.85e-04	164	47	3	5dbfcdd450f652b16d97da53b528d4584b0eabcf
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP2 INSM2 GAS2L2	6.85e-04	164	47	3	f1423f4434af4af9c60c8a5b0b0abec4a7df9401
ToppCell	facs-GAT-Fat-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PELI1 CELSR1 TTC24	7.10e-04	166	47	3	d22a08b415ef9e48398d69f3e45b04c33a085411
ToppCell	facs-GAT-Fat-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PELI1 CELSR1 RNF138	7.10e-04	166	47	3	3695407e4638f3c18fbff63daba52baa9256c429
ToppCell	Adult-Epithelial-lung_goblet_cell-D122\|Adult / Lineage, Cell type, age group and donor	ADAMTS10 CELSR1 INAVA	7.22e-04	167	47	3	6efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 UNC5CL RNF138	7.35e-04	168	47	3	273168eefe0dae5494ac6ff5306bb307f06dc9c5
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	NFXL1 CELSR1 EFNA3	7.35e-04	168	47	3	2fb2d916eb5000a637240d38e47a9b4f61f9f83f
ToppCell	control-Myeloid-pDC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TRIM66 TTC24 CASZ1	7.35e-04	168	47	3	affc39c7568b7df4b36af6f5b0e3702a18b6268c
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SALL4 CELSR1 INAVA	7.48e-04	169	47	3	40b557549fe08c5dc9dba359af35993d68d1640a
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L3MBTL1 SLCO2A1 SNAI2	7.48e-04	169	47	3	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 NRG3 ZNF467	7.61e-04	170	47	3	dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCell	15-Airway-Epithelial-Club-like_secretory\|Airway / Age, Tissue, Lineage and Cell class	TRIM66 CELSR1 INAVA	7.61e-04	170	47	3	1418031cc4b4a87a48621eb53a3c819cd713ddd0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 NRG3 ZNF467	7.61e-04	170	47	3	6035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 UNC5CL RNF138	7.61e-04	170	47	3	d74fbd995a8a37fc237f7147d398357b811d6452
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNAI1 VEGFD SNAI2	7.61e-04	170	47	3	e20568c8f3f17d94de78229617eb2f7e4c5af2bc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 NRG3 ZNF467	7.61e-04	170	47	3	c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 UNC5CL RNF138	7.61e-04	170	47	3	8e9b5f7bfb61f8d84d0b17fb0c191da4dabad63d
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PELI1 ZNF774 MBNL1	7.74e-04	171	47	3	2b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PELI1 ZNF774 MBNL1	7.74e-04	171	47	3	dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NFXL1 TRIM66 SNAI2	7.87e-04	172	47	3	80b565f6e37f38629f4cf89d5b053b3b8517244e
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 SNAI1 GEN1	7.87e-04	172	47	3	e359c59631f6a262429b6896a409f2ffbd4f6a76
ToppCell	facs-GAT-Fat-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 UNC5CL RNF138	7.87e-04	172	47	3	a9f0ccaca0d83bfec79e3251e346a165c34c242b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS10 NRG3 SLCO2A1	8.00e-04	173	47	3	afa6bb19df52541d8d17cbfac9cbdd18a5f3632d
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF384 PLK2 CASZ1	8.27e-04	175	47	3	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	(03)_Secretory-(4)_1wkpi\|(03)_Secretory / shred by cell type and Timepoint	PELI1 FBN1 VEGFD	8.27e-04	175	47	3	06b52f85baa31b55bb31477244892b6da79fe2c9
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNAI1 VEGFD SNAI2	8.41e-04	176	47	3	cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCell	facs-GAT-Fat-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZC3H3 UNC5CL RNF138	8.41e-04	176	47	3	acd05ca8952710feedbfe377b1330f3c2406d044
ToppCell	COPD-Epithelial-Aberrant_Basaloid\|COPD / Disease state, Lineage and Cell class	CELSR1 INAVA SLCO2A1	8.41e-04	176	47	3	11d867bcb4f2471b4e13a5f7dc1c24286197f26d
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	INSM2 CELSR1 CASZ1	8.41e-04	176	47	3	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 GAS2L2 UNC5CL	8.55e-04	177	47	3	ae01c19403a09f7ba5e4beafdfcd1b8eebdadcb7
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 SNAI1 SLCO2A1	8.55e-04	177	47	3	16197068260fc062bf8b730a51a199887ea580b9
ToppCell	facs-Lung-EPCAM-18m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 CASZ1 SLCO2A1	8.55e-04	177	47	3	2433924dcb085ebbe2545d476ebd7ee68e6092fb
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 GAS2L2 UNC5CL	8.55e-04	177	47	3	bd3d07bdef6e903995d4bbfb6ff3a5e1d9fb70cc
ToppCell	facs-BAT-Fat-3m-Lymphocytic-T_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PELI1 CELSR1 MBNL1	8.69e-04	178	47	3	7c101e3957ea9b0d4ebf619d1d02e7e64ae28915
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	ADAMTS10 FBN1 SNAI2	8.69e-04	178	47	3	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 INAVA NRG3	8.83e-04	179	47	3	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PELI1 FBN1 SLCO2A1	8.83e-04	179	47	3	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNAI1 VEGFD SNAI2	8.83e-04	179	47	3	948c2a01ec7a626c68281e6e796a9f0527a88591
ToppCell	COVID-19-kidney-Stressed_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PELI1 ZNF467 SLCO2A1	8.83e-04	179	47	3	754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SNAI1 VEGFD SNAI2	8.83e-04	179	47	3	b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCell	facs-Lung-EPCAM-18m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 CASZ1 SLCO2A1	8.97e-04	180	47	3	082c6116e0bbba8d9a3a82d14af55bdc8990c8c0
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 CASZ1 SLCO2A1	8.97e-04	180	47	3	53043d764fad9ac33ee40e356e562e759931adef
Disease	Weill-Marchesani syndrome	ADAMTS10 FBN1	6.51e-06	3	44	2	C0265313
Disease	Weill-Marchesani Syndrome, Autosomal Dominant	ADAMTS10 FBN1	6.51e-06	3	44	2	C1869115
Disease	Weill-Marchesani Syndrome, Autosomal Recessive	ADAMTS10 FBN1	6.51e-06	3	44	2	C1869114
Disease	Weill-Marchesani syndrome (implicated_via_orthology)	ADAMTS10 FBN1	6.51e-06	3	44	2	DOID:0050475 (implicated_via_orthology)
Disease	Weill-Marchesani syndrome	ADAMTS10 FBN1	1.30e-05	4	44	2	cv:C0265313
Disease	Weill-Marchesani syndrome (is_implicated_in)	ADAMTS10 FBN1	1.30e-05	4	44	2	DOID:0050475 (is_implicated_in)
Disease	carcinoma (implicated_via_orthology)	SALL4 SNAI1 SNAI2	1.21e-04	64	44	3	DOID:305 (implicated_via_orthology)
Disease	brain cancer (implicated_via_orthology)	INSM2 L3MBTL1	6.90e-04	26	44	2	DOID:1319 (implicated_via_orthology)
Disease	cataract	EFNA3 CASZ1 PKD1L1	1.23e-03	141	44	3	MONDO_0005129
Disease	Familial thoracic aortic aneurysm and aortic dissection	ADAMTS10 FBN1	2.85e-03	53	44	2	C4707243

Protein segments in the cluster

Peptide	Gene	Start	Entry
RSHCSPSERSHCSPS	C2orf16	1756	Q68DN1
SAARHPSSPCSVKHS	BRD1	11	O95696
KTTHFHCRRPGCTFT	CASZ1	606	Q86V15
SFAGHPCTRASGHPC	AGRN	1816	O00468
LPCDCFPHGSHSRTC	CELSR1	2001	Q9NYQ6
HGFEILCSKCSPHFS	ECD	306	O95905
CKSADHRATLPPAHC	ADAMTS10	971	Q9H324
SVKHHRSLSSCCSPG	NRG3	466	P56975
KEQCSRPPTCHHTSQ	NFXL1	551	Q6ZNB6
SFHHRKCPTPGCDGS	L3MBTL1	616	Q9Y468
CESGPHDVHKCSPRE	LRP2	256	P98164
SCKHCPSTFFSSPGL	INSM2	526	Q96T92
TTHPPSHRAGASCVC	NFYC	351	Q13952
SSPVKYCCFTPSGHH	GUCD1	161	Q96NT3
CCASTSHSGEKPVPT	EFNA3	166	P52797
GFTCKCPPGFTQHHT	FBN1	2506	P35555
GKKRFGHICSSHPSC	CERK	476	Q8TCT0
PCRCTSLSHKPGSFL	GAS2L2	271	Q8NHY3
TCSRPDTECKFAHPS	MBNL1	26	Q9NR56
CSVCSHPGSPKDHER	GEN1	261	Q17RS7
SHTCPCGVPACSHKA	CRIPAK	386	Q8N1N5
SHQPTSPGSKDCHRE	SALL4	121	Q9UJQ4
THFVQCPSVPSHKFC	IRF2BP2	516	Q7Z5L9
TKPPLPHAACHSCSE	INAVA	441	Q3KP66
SRTSLMGKSHCCPPH	PKD1L1	2096	Q8TDX9
CSFEISSLHSPHCKR	PRR14L	1896	Q5THK1
THAFSPCGHVCSEKT	PELI1	361	Q96FA3
THTGEKPFSCPHCNR	SNAI2	206	O43623
SSGHPTFKCPLCQES	RNF138	151	Q8WVD3
SAKTGSCPVPCAHFL	SLCO2A1	501	Q92959
THTGEKPFSCPHCSR	SNAI1	201	O95863
HRSSPSDTRPKCGFC	PHF6	201	Q8IWS0
PHKCPHCSKTFANTS	ZNF384	316	Q8TF68
ARVSCSPHSAKGTCP	WDR90	1086	Q96KV7
GTCKKTDGTCPFSHH	ZC3H3	706	Q8IXZ2
SSCPTFTKHTPCRGT	TTC24	501	A2A3L6
VCGKGFSRPDHLSCH	VEZF1	236	Q14119
HSGERPFSCPDCHKS	ZNF774	341	Q6NX45
PCTLTFKHCAEQPSH	UNC5CL	176	Q8IV45
HRTHTGTKPFGCSDC	ZNF84	366	P51523
RTHTGVKPHKCSECG	ZNF26	306	P17031
SCCHTVPDFHLSSPA	PLK2	346	Q9NYY3
DRCPFHTRPCASGKT	VEGFD	316	O43915
CSSCTEEHRHSPVPG	TRIM66	26	O15016
HQRTHTGEKPFTCPT	ZNF202	611	O95125
SHQKTHTGERPFPCT	ZNF467	261	Q7Z7K2
PHKCSHCGRTFSHIT	ZNF836	721	Q6ZNA1
RSSHSGEKPHHCPVC	ZNF358	226	Q9NW07
THTGEKPHTCSECGK	ZNF649	311	Q9BS31