Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription coactivator activity

NCOA2 BCL9L NCOA3 KMT2C NCOA6 MAML2 SS18 EP300 SS18L1

4.20e-09303389GO:0003713
GeneOntologyMolecularFunctionnuclear receptor binding

NCOA2 NCOA3 FOXP1 NCOA6 LATS1 FOXP2 EP300

5.57e-08187387GO:0016922
GeneOntologyMolecularFunctiontranscription coregulator activity

NCOA2 BCL9L NCOA3 KMT2C NCOA6 MAML2 SS18 CNOT2 EP300 SS18L1

6.69e-085623810GO:0003712
GeneOntologyMolecularFunctionnuclear androgen receptor binding

NCOA3 FOXP1 FOXP2 EP300

4.38e-0733384GO:0050681
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NCOA2 BCL9L NCOA3 KMT2C NCOA6 MAML2 UBQLN2 SS18 RBM33 CNOT2 EP300 SS18L1

9.23e-0711603812GO:0030674
GeneOntologyMolecularFunctionnuclear estrogen receptor binding

NCOA2 NCOA3 NCOA6 LATS1

3.05e-0653384GO:0030331
GeneOntologyMolecularFunctionmolecular adaptor activity

NCOA2 BCL9L NCOA3 KMT2C NCOA6 MAML2 UBQLN2 SS18 RBM33 CNOT2 EP300 SS18L1

4.73e-0613563812GO:0060090
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

NCOA2 NCOA3 NCOA6 SS18

5.38e-0661384GO:0030374
GeneOntologyMolecularFunctionnuclear glucocorticoid receptor binding

NCOA2 NCOA6 EP300

7.09e-0620383GO:0035259
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

NCOA3 NCOA6 EP300

8.26e-0621383GO:0042975
GeneOntologyMolecularFunctiontranscription factor binding

NCOA2 NCOA3 FOXP1 NCOA6 NOP58 LATS1 FOXP2 CNOT2 EP300

8.96e-06753389GO:0008134
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

NCOA2 NCOA3 FOXP1 NCOA6 LATS1 FOXP2 EP300

1.19e-05417387GO:0061629
GeneOntologyMolecularFunctionnuclear thyroid hormone receptor binding

NCOA2 NCOA3 NCOA6

3.65e-0534383GO:0046966
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

NCOA2 NCOA3 FOXP1 NCOA6 LATS1 FOXP2 EP300

9.91e-05582387GO:0140297
GeneOntologyMolecularFunctiontranscription coregulator binding

FOXP1 FOXP2 CNOT2 EP300

1.42e-04140384GO:0001221
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

FOXP1 FOXP4 KLF17 FOXP2 SMAD5

3.33e-04320385GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

FOXP1 FOXP4 KLF17 FOXP2 SMAD5

3.63e-04326385GO:0001217
GeneOntologyMolecularFunctionnuclear retinoid X receptor binding

NCOA2 NCOA6

8.70e-0423382GO:0046965
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

NCOA2 NCOA3 FOXP1 FOXP4 KLF17 FOXP2 DACH2 EP300 SMAD5

1.36e-031459389GO:0000977
GeneOntologyMolecularFunctionnucleocytoplasmic carrier activity

IPO11 XPO7

1.69e-0332382GO:0140142
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

NCOA2 FOXP1 FOXP4 KLF17 FOXP2 DACH2 EP300 SMAD5

2.03e-031244388GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

NCOA2 FOXP1 FOXP4 KLF17 FOXP2 DACH2 EP300 SMAD5

2.32e-031271388GO:0000987
GeneOntologyMolecularFunctionhistone acetyltransferase activity

NCOA3 EP300

4.24e-0351382GO:0004402
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

NCOA3 EP300

4.91e-0355382GO:0061733
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

NCOA2 NCOA6

4.91e-0355382GO:0042974
GeneOntologyMolecularFunctionpolyubiquitin modification-dependent protein binding

UBQLN2 UBQLN4

5.64e-0359382GO:0031593
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

NCOA3 EP300

5.82e-0360382GO:0034212
GeneOntologyMolecularFunctionmodification-dependent protein binding

UBQLN2 EP300 UBQLN4

7.00e-03206383GO:0140030
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

NCOA3 NOP58

7.01e-0366382GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

NCOA3 NOP58

7.01e-0366382GO:0001098
GeneOntologyMolecularFunctionhistone modifying activity

NCOA3 KMT2C EP300

9.35e-03229383GO:0140993
GeneOntologyMolecularFunctionN-acetyltransferase activity

NCOA3 EP300

9.67e-0378382GO:0008080
GeneOntologyMolecularFunctionSMAD binding

EP300 SMAD5

1.17e-0286382GO:0046332
GeneOntologyBiologicalProcessregulation of intracellular steroid hormone receptor signaling pathway

NCOA2 NCOA3 FOXP1 LATS1 CNOT2 EP300

9.90e-0987376GO:0033143
GeneOntologyBiologicalProcessnuclear receptor-mediated steroid hormone signaling pathway

NCOA2 NCOA3 FOXP1 LATS1 CNOT2 EP300

1.45e-07136376GO:0030518
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

NCOA2 NCOA3 FOXP1 LATS1 CNOT2 EP300

3.13e-07155376GO:0043401
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

NCOA2 NCOA3 FOXP1 LATS1 CNOT2 EP300

1.48e-06202376GO:0141193
GeneOntologyBiologicalProcessnegative regulation of lung goblet cell differentiation

FOXP1 FOXP4

3.13e-062372GO:1901250
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

NCOA2 BCL9L NCOA3 KMT2C FOXP1 NCOA6 BMPR2 MAML2 SS18 EP300 SS18L1 SMAD5

3.19e-0613903712GO:0045944
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

NCOA2 NCOA3 FOXP1 LATS1 CNOT2 EP300

3.91e-06239376GO:0071383
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

NCOA2 NCOA3 FOXP1 LATS1 CNOT2 EP300

4.41e-06244376GO:0009755
GeneOntologyBiologicalProcessregulation of lung goblet cell differentiation

FOXP1 FOXP4

9.38e-063372GO:1901249
GeneOntologyBiologicalProcessinnate vocalization behavior

FOXP1 FOXP2

9.38e-063372GO:0098582
GeneOntologyBiologicalProcessvocalization behavior

FOXP1 FOXP2 NLGN4Y

1.05e-0524373GO:0071625
GeneOntologyBiologicalProcessembryo development

NCOA3 FOXP1 NCOA6 FOXP4 BMPR2 LATS1 FOXP2 DYNC2H1 CNOT2 EP300 SMAD5

2.85e-0514373711GO:0009790
GeneOntologyBiologicalProcessregulation of intracellular estrogen receptor signaling pathway

NCOA3 LATS1 CNOT2

3.64e-0536373GO:0033146
GeneOntologyBiologicalProcesslung goblet cell differentiation

FOXP1 FOXP4

4.68e-056372GO:0060480
GeneOntologyBiologicalProcessresponse to steroid hormone

NCOA2 NCOA3 FOXP1 LATS1 CNOT2 EP300

5.47e-05381376GO:0048545
GeneOntologyBiologicalProcesslobar bronchus epithelium development

FOXP1 FOXP4

6.54e-057372GO:0060481
GeneOntologyBiologicalProcesspositive regulation of hydrogen peroxide-mediated programmed cell death

FOXP1 EP300

6.54e-057372GO:1901300
GeneOntologyBiologicalProcesscellular response to organic cyclic compound

NCOA2 NCOA3 FOXP1 LATS1 CNOT2 EP300 SMAD5

8.64e-05605377GO:0071407
GeneOntologyBiologicalProcesslobar bronchus development

FOXP1 FOXP4

8.71e-058372GO:0060482
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

NCOA2 NCOA3 FOXP1 LATS1 CNOT2 EP300

8.89e-05416376GO:0030522
GeneOntologyBiologicalProcesslung development

FOXP1 FOXP4 BMPR2 FOXP2 EP300

1.13e-04269375GO:0030324
GeneOntologyBiologicalProcessrespiratory tube development

FOXP1 FOXP4 BMPR2 FOXP2 EP300

1.21e-04273375GO:0030323
GeneOntologyBiologicalProcessestrogen receptor signaling pathway

NCOA3 LATS1 CNOT2

1.45e-0457373GO:0030520
GeneOntologyBiologicalProcesslung epithelium development

FOXP1 FOXP4 FOXP2

1.78e-0461373GO:0060428
GeneOntologyBiologicalProcesshead development

FOXP1 NCOA6 CFAP43 FOXP2 FCGR2A DYNC2H1 NLGN4Y EP300

1.84e-04919378GO:0060322
GeneOntologyBiologicalProcessrespiratory system development

FOXP1 FOXP4 BMPR2 FOXP2 EP300

2.02e-04305375GO:0060541
GeneOntologyBiologicalProcessbronchus development

FOXP1 FOXP4

2.41e-0413372GO:0060433
GeneOntologyBiologicalProcesslung secretory cell differentiation

FOXP1 FOXP4

3.24e-0415372GO:0061140
GeneOntologyBiologicalProcessheart development

FOXP1 NCOA6 FOXP4 BMPR2 DYNC2H1 EP300 SMAD5

3.43e-04757377GO:0007507
GeneOntologyBiologicalProcessregulation of stem cell population maintenance

NCOA3 SS18 CNOT2

3.68e-0478373GO:2000036
GeneOntologyBiologicalProcessmuscle tissue development

BCL9L FOXP1 BMPR2 FOXP2 EP300 SMAD5

4.35e-04558376GO:0060537
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

NCOA2 FOXP1 FOXP4 KLF17 FOXP2 CNOT2 EP300 SMAD5

4.61e-041053378GO:0000122
GeneOntologyBiologicalProcesspositive regulation of intracellular steroid hormone receptor signaling pathway

NCOA2 NCOA3

4.70e-0418372GO:0033145
GeneOntologyBiologicalProcessregulation of hydrogen peroxide-mediated programmed cell death

FOXP1 EP300

5.25e-0419372GO:1901298
GeneOntologyBiologicalProcessendocytosis

SYNRG CLINT1 UBQLN2 ARHGAP27 FCGR2A LYST NLGN4Y

5.84e-04827377GO:0006897
GeneOntologyBiologicalProcessskeletal muscle tissue development

BCL9L FOXP1 FOXP2 EP300

6.64e-04223374GO:0007519
GeneOntologyBiologicalProcesshydrogen peroxide-mediated programmed cell death

FOXP1 EP300

7.07e-0422372GO:0010421
GeneOntologyBiologicalProcessstriatum development

FOXP1 FOXP2

7.07e-0422372GO:0021756
GeneOntologyBiologicalProcessbrain development

FOXP1 NCOA6 CFAP43 FOXP2 FCGR2A DYNC2H1 NLGN4Y

7.31e-04859377GO:0007420
GeneOntologyBiologicalProcessstem cell population maintenance

BCL9L NCOA3 SS18 CNOT2

8.33e-04237374GO:0019827
GeneOntologyBiologicalProcessprogrammed cell death in response to reactive oxygen species

FOXP1 EP300

8.43e-0424372GO:0097468
GeneOntologyBiologicalProcessskeletal muscle organ development

BCL9L FOXP1 FOXP2 EP300

8.73e-04240374GO:0060538
GeneOntologyBiologicalProcessmaintenance of cell number

BCL9L NCOA3 SS18 CNOT2

9.01e-04242374GO:0098727
GeneOntologyBiologicalProcessdevelopmental growth

NCOA3 KMT2C FOXP1 BMPR2 LATS1 NLGN4Y EP300

1.03e-03911377GO:0048589
GeneOntologyBiologicalProcesscell morphogenesis

BCL9L FOXP1 BMPR2 CFAP43 LATS1 SS18 EP300 SS18L1

1.06e-031194378GO:0000902
GeneOntologyBiologicalProcessorgan growth

FOXP1 LATS1 NLGN4Y EP300

1.11e-03256374GO:0035265
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

BCL9L BMPR2 LATS1 EP300 SMAD5

1.13e-03445375GO:0141091
GeneOntologyBiologicalProcesssubpallium development

FOXP1 FOXP2

1.15e-0328372GO:0021544
GeneOntologyBiologicalProcesssmooth muscle tissue development

FOXP1 FOXP2

1.23e-0329372GO:0048745
GeneOntologyBiologicalProcessgrowth

NCOA3 KMT2C FOXP1 BMPR2 LATS1 FOXP2 NLGN4Y EP300

1.31e-031235378GO:0040007
GeneOntologyBiologicalProcessregulation of androgen receptor signaling pathway

FOXP1 EP300

1.41e-0331372GO:0060765
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

BCL9L LATS1 EP300 SMAD5

1.46e-03276374GO:0007179
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

BCL9L BMPR2 LATS1 EP300 SMAD5

1.61e-03482375GO:0007178
GeneOntologyBiologicalProcesscellular response to hormone stimulus

NCOA2 NCOA3 FOXP1 LATS1 CNOT2 EP300

1.72e-03727376GO:0032870
GeneOntologyCellularComponenttranscription regulator complex

NCOA2 BCL9L NCOA3 NCOA6 DACH2 EP300 SMAD5

8.65e-05596387GO:0005667
GeneOntologyCellularComponentnuclear protein-containing complex

NCOA2 BCL9L NCOA3 KMT2C NCOA6 SS18 SS18L1 SMAD5 UBQLN4 XPO7

1.28e-0413773810GO:0140513
GeneOntologyCellularComponentMLL3/4 complex

KMT2C NCOA6

2.10e-0412382GO:0044666
GeneOntologyCellularComponentchromatin

NCOA2 NCOA3 FOXP1 FOXP4 KLF17 FOXP2 SS18 EP300 SS18L1 SMAD5

2.32e-0414803810GO:0000785
GeneOntologyCellularComponentinhibitory synapse

NLGN4Y DTNB

1.45e-0331382GO:0060077
GeneOntologyCellularComponentRNA polymerase II transcription regulator complex

NCOA2 BCL9L NCOA3 SMAD5

1.46e-03272384GO:0090575
GeneOntologyCellularComponentclathrin vesicle coat

SYNRG CLINT1

2.17e-0338382GO:0030125
MousePhenoabnormal myocardium compact layer morphology

FOXP1 NCOA6 BMPR2 EP300

1.20e-0567304MP:0004056
MousePhenoprenatal lethality, incomplete penetrance

KMT2C NCOA6 FOXP4 BMPR2 CFAP43 LATS1 FOXP2 EP300 XPO7

1.75e-05747309MP:0011101
MousePhenoprenatal lethality prior to heart atrial septation, incomplete penetrance

KMT2C NCOA6 FOXP4 BMPR2 FOXP2 EP300 XPO7

2.01e-05410307MP:0031660
MousePhenoembryonic lethality, incomplete penetrance

KMT2C NCOA6 FOXP4 BMPR2 FOXP2 EP300 XPO7

2.01e-05410307MP:0011102
MousePhenoabnormal heart development

FOXP1 NCOA6 FOXP4 DYNC2H1 EP300 SMAD5

1.18e-04372306MP:0000267
MousePhenothin myocardium compact layer

FOXP1 NCOA6 EP300

1.27e-0446303MP:0004057
DomainFOXP-CC

FOXP1 FOXP4 FOXP2

3.10e-084383PF16159
DomainFOXP-CC

FOXP1 FOXP4 FOXP2

3.10e-084383IPR032354
DomainNuc_rcpt_coact

NCOA2 NCOA3 EP300

1.55e-076383IPR009110
DomainDUF4927

NCOA2 NCOA3

4.03e-062382PF16279
DomainDUF4927

NCOA2 NCOA3

4.03e-062382IPR032565
DomainDUF1518

NCOA2 NCOA3

1.21e-053382PF07469
DomainDUF1518

NCOA2 NCOA3

1.21e-053382IPR010011
DomainSrc1_rcpt_coact

NCOA2 NCOA3

1.21e-053382IPR008955
DomainNuclear_rcpt_coactivator

NCOA2 NCOA3

1.21e-053382IPR017426
DomainSSXT

SS18 SS18L1

1.21e-053382PF05030
DomainDUF1518

NCOA2 NCOA3

1.21e-053382SM01151
DomainNuc_rcpt_coact_Ncoa-typ

NCOA2 NCOA3

1.21e-053382IPR014920
DomainSS18_fam

SS18 SS18L1

1.21e-053382IPR007726
DomainSRC-1

NCOA2 NCOA3

1.21e-053382IPR014935
DomainSRC-1

NCOA2 NCOA3

1.21e-053382PF08832
Domain-

NCOA2 NCOA3

1.21e-0533824.10.630.10
DomainNuc_rec_co-act

NCOA2 NCOA3

1.21e-053382PF08815
DomainUBA

LATS1 UBQLN2 UBQLN4

5.30e-0536383PF00627
DomainUbiquilin

UBQLN2 UBQLN4

6.02e-056382IPR015496
DomainUBA

LATS1 UBQLN2 UBQLN4

9.71e-0544383IPR015940
DomainTF_fork_head_CS_2

FOXP1 FOXP4 FOXP2

1.11e-0446383IPR030456
DomainUBA

LATS1 UBQLN2 UBQLN4

1.18e-0447383PS50030
DomainTF_fork_head_CS_1

FOXP1 FOXP4 FOXP2

1.18e-0447383IPR018122
DomainFORK_HEAD_3

FOXP1 FOXP4 FOXP2

1.34e-0449383PS50039
DomainFH

FOXP1 FOXP4 FOXP2

1.34e-0449383SM00339
DomainFORK_HEAD_1

FOXP1 FOXP4 FOXP2

1.34e-0449383PS00657
DomainFORK_HEAD_2

FOXP1 FOXP4 FOXP2

1.34e-0449383PS00658
DomainForkhead

FOXP1 FOXP4 FOXP2

1.34e-0449383PF00250
DomainFork_head_dom

FOXP1 FOXP4 FOXP2

1.34e-0449383IPR001766
DomainSTI1_HS-bd

UBQLN2 UBQLN4

1.80e-0410382IPR006636
DomainSTI1

UBQLN2 UBQLN4

1.80e-0410382SM00727
DomainUBA-like

LATS1 UBQLN2 UBQLN4

2.97e-0464383IPR009060
DomainIMPORTIN_B_NT

IPO11 XPO7

3.61e-0414382PS50166
DomainIBN_N

IPO11 XPO7

4.16e-0415382PF03810
DomainIBN_N

IPO11 XPO7

4.75e-0416382SM00913
DomainImportin-beta_N

IPO11 XPO7

5.38e-0417382IPR001494
DomainZF_ZZ_2

DTNB EP300

6.04e-0418382PS50135
DomainZF_ZZ_1

DTNB EP300

6.04e-0418382PS01357
DomainZZ

DTNB EP300

6.04e-0418382PF00569
DomainZnf_ZZ

DTNB EP300

6.74e-0419382IPR000433
Domain6-PGluconate_DH_C-like

UBQLN2 UBQLN4

6.74e-0419382IPR008927
DomainZnF_ZZ

DTNB EP300

6.74e-0419382SM00291
DomainPAS

NCOA2 NCOA3

1.17e-0325382PF00989
DomainPAS_fold

NCOA2 NCOA3

1.17e-0325382IPR013767
DomainUBA

UBQLN2 UBQLN4

1.69e-0330382SM00165
DomainPAS

NCOA2 NCOA3

1.92e-0332382SM00091
DomainPAS

NCOA2 NCOA3

2.17e-0334382IPR000014
DomainPAS

NCOA2 NCOA3

2.17e-0334382PS50112
DomainUBIQUITIN_1

UBQLN2 UBQLN4

2.57e-0337382PS00299
DomainUBQ

UBQLN2 UBQLN4

3.45e-0343382SM00213
Domainubiquitin

UBQLN2 UBQLN4

4.11e-0347382PF00240
DomainARM-type_fold

UBQLN2 LYST IPO11 XPO7

4.84e-03339384IPR016024
DomainUBIQUITIN_2

UBQLN2 UBQLN4

5.40e-0354382PS50053
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

NCOA2 NCOA6 EP300

5.61e-0618283M26942
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

NCOA2 NCOA3 NCOA6 EP300

2.15e-0584284M1008
PathwayPID_RETINOIC_ACID_PATHWAY

NCOA2 NCOA3 EP300

2.75e-0530283M207
PathwayREACTOME_ADIPOGENESIS

NCOA2 NCOA3 NCOA6 EP300

6.22e-05110284M48259
PathwayKEGG_MEDICUS_REFERENCE_BMP15_SIGNALING_PATHWAY

BMPR2 SMAD5

7.94e-057282M47845
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

NCOA2 NCOA3 NCOA6 EP300

8.18e-05118284M27316
PathwayREACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

NCOA3 KMT2C NCOA6 EP300

9.31e-05122284M29689
PathwayREACTOME_HEME_SIGNALING

NCOA2 NCOA6 EP300

1.22e-0449283M41832
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

KMT2C NCOA6 SS18 EP300 SS18L1

1.28e-04254285M27131
PathwayKEGG_MEDICUS_REFERENCE_BMP9_10_SIGNALING_PATHWAY

BMPR2 SMAD5

1.36e-049282M47822
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

MAML2 EP300

1.70e-0410282MM15535
PathwayPID_ALK2_PATHWAY

BMPR2 SMAD5

2.07e-0411282M203
PathwayKEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY

BMPR2 SMAD5

2.07e-0411282M47848
PathwayKEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY

NCOA2 NCOA3

2.07e-0411282M47503
PathwayREACTOME_NOTCH2_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML2 EP300

2.48e-0412282M27159
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

NCOA2 NCOA3 KMT2C FOXP1 NCOA6 MAML2 SS18 CNOT2 EP300 SS18L1

2.67e-0414322810M509
PathwayPID_ERA_GENOMIC_PATHWAY

NCOA2 NCOA3 EP300

2.70e-0464283M200
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

KMT2C FOXP2 EP300

2.82e-0465283M39682
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

MAML2 EP300

3.41e-0414282M27808
PathwayREACTOME_CIRCADIAN_CLOCK

NCOA2 NCOA6 EP300

3.51e-0470283M938
PathwayPID_ERB_GENOMIC_PATHWAY

NCOA2 NCOA3

3.93e-0415282M119
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

MAML2 EP300

4.49e-0416282M27121
PathwayREACTOME_SIGNALING_BY_NOTCH1

MAML2 EP300

5.71e-0418282MM14775
PathwayKEGG_TGF_BETA_SIGNALING_PATHWAY

BMPR2 EP300 SMAD5

6.43e-0486283M2642
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML2 EP300

7.07e-0420282M27881
PathwayKEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY

BMPR2 SMAD5

7.07e-0420282M47843
PathwayWP_ANDROGEN_RECEPTOR_SIGNALING

NCOA2 NCOA3 EP300

7.58e-0491283M39700
PathwayBIOCARTA_VDR_PATHWAY

NCOA3 EP300

8.57e-0422282MM1370
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML2 EP300

1.11e-0325282M27880
PathwayPID_ALK1_PATHWAY

BMPR2 SMAD5

1.20e-0326282M185
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9L EP300

1.20e-0326282MM14793
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

NCOA2 NCOA6

1.29e-0327282M26943
PathwayWP_KLEEFSTRA_SYNDROME

KMT2C NCOA6

1.49e-0329282M48076
PathwayWP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY

NCOA2 NCOA6

1.71e-0331282M39476
PathwayREACTOME_SIGNALING_BY_BMP

BMPR2 SMAD5

1.71e-0331282M1662
PathwayREACTOME_SIGNALING_BY_BMP

BMPR2 SMAD5

1.71e-0331282MM14789
PathwayWP_PREGNANE_X_RECEPTOR_PATHWAY

NCOA2 NCOA3

1.82e-0332282M39567
PathwayREACTOME_SIGNALING_BY_NOTCH2

MAML2 EP300

1.93e-0333282M604
PathwayBIOCARTA_ALK_PATHWAY

BMPR2 SMAD5

2.43e-0337282M17400
PathwayREACTOME_SIGNALING_BY_NOTCH

MAML2 EP300

2.69e-0339282MM14604
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_PIGMENTATION

SS18 SS18L1

3.12e-0342282M48237
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

MAML2 EP300

3.12e-0342282M17541
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

KMT2C NCOA6

3.12e-0342282M48018
PathwayPID_BMP_PATHWAY

BMPR2 SMAD5

3.12e-0342282M181
PathwayREACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP

NCOA2 NCOA6

3.12e-0342282M27172
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

NCOA2 NCOA3 EP300

3.12e-03149283M27888
PathwayWP_NUCLEAR_RECEPTORS_METAPATHWAY

NCOA2 NCOA3 NCOA6 EP300

3.24e-03314284M39428
PathwayPID_HNF3A_PATHWAY

NCOA3 EP300

3.42e-0344282M285
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

NCOA2 EP300

3.42e-0344282M27295
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

BMPR2 EP300 SMAD5

3.88e-03161283M27871
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

MAML2 EP300

3.89e-0347282M7946
PathwayPID_HES_HEY_PATHWAY

MAML2 EP300

4.06e-0348282M288
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML2 EP300

4.06e-0348282M611
PathwayREACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_CYCLE_GENES

CNOT2 EP300

4.22e-0349282M27614
PathwayREACTOME_SIGNALING_BY_NOTCH3

MAML2 EP300

4.22e-0349282M618
PathwayWP_ID_SIGNALING_PATHWAY

BMPR2 SMAD5

4.39e-0350282MM15817
PathwayPID_AR_TF_PATHWAY

NCOA2 EP300

4.92e-0353282M151
PathwayWP_TGFBETA_SIGNALING_PATHWAY

EP300 SMAD5

4.92e-0353282MM15880
PathwayWP_TGFBETA_RECEPTOR_SIGNALING

EP300 SMAD5

5.29e-0355282M39351
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS

NCOA2 NCOA6

5.29e-0355282M27145
PathwayREACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF

NCOA2 NCOA6

5.29e-0355282M27001
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

MAML2 EP300

5.87e-0358282M29616
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

EP300 SMAD5

6.07e-0359282M39886
PathwayPID_NOTCH_PATHWAY

MAML2 EP300

6.07e-0359282M17
PathwayREACTOME_SUMOYLATION

NCOA2 NOP58 EP300

6.07e-03189283M27214
PathwayREACTOME_CYTOPROTECTION_BY_HMOX1

NCOA2 NCOA6

6.27e-0360282M41830
PathwayWP_NOTCH_SIGNALING_WP61

MAML2 EP300

6.48e-0361282M39540
PathwayPID_AR_PATHWAY

NCOA2 NCOA6

6.48e-0361282M58
Pubmed

Human transcription factor protein interaction networks.

NCOA2 BCL9L NCOA3 KMT2C FOXP1 NCOA6 FOXP4 SCAF11 FOXP2 SS18 SMAP2 RBM33 CNOT2 EP300 SS18L1 SMAD5

5.74e-131429381635140242
Pubmed

Interaction network of human early embryonic transcription factors.

NCOA2 BCL9L NCOA3 KMT2C FOXP1 NCOA6 FOXP4 FOXP2 EP300 SS18L1

3.55e-12351381038297188
Pubmed

Foxp4: a novel member of the Foxp subfamily of winged-helix genes co-expressed with Foxp1 and Foxp2 in pulmonary and gut tissues.

FOXP1 FOXP4 FOXP2

1.20e-09338314516685
Pubmed

Human-specific transcriptional regulation of CNS development genes by FOXP2.

FOXP1 FOXP4 FOXP2

1.20e-09338319907493
Pubmed

Protein-Protein Interaction Among the FoxP Family Members and their Regulation of Two Target Genes, VLDLR and CNTNAP2 in the Zebra Finch Song System.

FOXP1 FOXP4 FOXP2

1.20e-09338328507505
Pubmed

Transcriptional regulation by FOXP1, FOXP2, and FOXP4 dimerization.

FOXP1 FOXP4 FOXP2

1.20e-09338325027557
Pubmed

Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions.

FOXP1 FOXP4 FOXP2

4.81e-09438314701752
Pubmed

Identification and characterization of T reg-like cells in zebrafish.

FOXP1 FOXP4 FOXP2

4.81e-09438329066577
Pubmed

T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.

NCOA2 NCOA3 NCOA6 EP300

5.79e-092038411877444
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

NCOA2 NCOA3 NCOA6 EP300

7.15e-092138419596656
Pubmed

Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains.

NCOA2 NCOA3 EP300

1.20e-08538312714702
Pubmed

SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.

NCOA2 NCOA3 EP300

1.20e-0853839812974
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NCOA2 BCL9L NCOA3 FOXP1 NCOA6 FOXP4 RBM33

1.54e-0826838733640491
Pubmed

Generation of mice with a conditional Foxp2 null allele.

FOXP1 FOXP4 FOXP2

2.40e-08638317619227
Pubmed

Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.

FOXP1 FOXP4 FOXP2

2.40e-08638328591638
Pubmed

Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly.

NCOA2 NCOA3 EP300

2.40e-08638316923966
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

NCOA2 BCL9L NCOA3 KMT2C NCOA6 RBM33 CNOT2 EP300

2.89e-0845738832344865
Pubmed

Foxp1/2/4-NuRD interactions regulate gene expression and epithelial injury response in the lung via regulation of interleukin-6.

FOXP1 FOXP4 FOXP2

4.20e-08738320185820
Pubmed

The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine.

NCOA2 NCOA3 EP300

4.20e-08738312709428
Pubmed

Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1.

FOXP1 FOXP4 FOXP2 SMAD5

4.84e-083338418662545
Pubmed

The activation function-1 domain of Nur77/NR4A1 mediates trans-activation, cell specificity, and coactivator recruitment.

NCOA2 NCOA3 EP300

6.71e-08838312082103
Pubmed

Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu.

NCOA2 NCOA3 EP300

6.71e-08838314747462
Pubmed

Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation.

NCOA3 BMPR2 SMAD5

6.71e-08838310504300
Pubmed

Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase.

NCOA2 NCOA3 EP300

6.71e-08838310490106
Pubmed

Regulation of somatic growth by the p160 coactivator p/CIP.

NCOA2 NCOA3 EP300

1.01e-07938311087842
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NCOA2 SYNRG KMT2C NCOA6 NOP58 CLINT1 LATS1 EP300

1.18e-0754938838280479
Pubmed

Forkhead Box Protein P1 Is Dispensable for Retina but Essential for Lens Development.

FOXP1 FOXP4 FOXP2

1.44e-071038328384713
Pubmed

Foxp1/2/4 regulate endochondral ossification as a suppresser complex.

FOXP1 FOXP4 FOXP2

1.97e-071138325527076
Pubmed

The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.

NCOA2 NCOA3 NCOA6

1.97e-071138336613751
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NCOA2 NCOA3 KMT2C FOXP1 NCOA6 NOP58 CLINT1 RBM33 EP300 IPO11

2.08e-071103381034189442
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NCOA2 NCOA3 KMT2C FOXP1 FOXP4 DYNC2H1 EP300

2.27e-0739838735016035
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NCOA2 KMT2C FOXP1 PTPN4 FOXP4 SCAF11 BMPR2 NLGN4Y DTNB EP300 XPO7

3.53e-071489381128611215
Pubmed

Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.

NCOA2 KMT2C NCOA6

4.34e-071438312482968
Pubmed

Multiplexed molecular interactions of nuclear receptors using fluorescent microspheres.

NCOA2 NCOA3 EP300

4.34e-071438311500849
Pubmed

New nomenclature for chromatin-modifying enzymes.

NCOA2 NCOA3 KMT2C EP300

4.59e-075738418022353
Pubmed

SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.

KMT2C NCOA6 EP300

6.67e-071638323870121
Pubmed

The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice.

FOXP1 FOXP4 FOXP2

6.67e-071638326021489
Pubmed

Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS.

FOXP1 FOXP4 FOXP2

6.67e-071638322542185
Pubmed

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.

FOXP1 FOXP2 SS18 SS18L1

7.82e-076538426655900
Pubmed

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

NCOA2 NCOA3 EP300

8.10e-071738319183483
Pubmed

Differential and Overlapping Pattern of Foxp1 and Foxp2 Expression in the Striatum of Adult Mouse Brain.

FOXP1 FOXP2

1.16e-06238230031127
Pubmed

Foxp2 regulates anatomical features that may be relevant for vocal behaviors and bipedal locomotion.

FOXP1 FOXP2

1.16e-06238230104377
Pubmed

Foxp1 and Foxp4 Deletion Causes the Loss of Follicle Stem Cell Niche and Cyclic Hair Shedding by Inducing Inner Bulge Cell Apoptosis.

FOXP1 FOXP4

1.16e-06238235759955
Pubmed

Homeostatic levels of SRC-2 and SRC-3 promote early human adipogenesis.

NCOA2 NCOA3

1.16e-06238221220509
Pubmed

Uterine Tumor Resembling Ovarian Sex Cord Tumor: A Distinct Entity Characterized by Recurrent NCOA2/3 Gene Fusions.

NCOA2 NCOA3

1.16e-06238230273195
Pubmed

p300 interacts with the nuclear proto-oncoprotein SYT as part of the active control of cell adhesion.

SS18 EP300

1.16e-06238211030627
Pubmed

A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells.

NCOA2 NCOA3

1.16e-06238230048685
Pubmed

Investigating protein-protein interactions in live cells using bioluminescence resonance energy transfer.

FOXP1 FOXP2

1.16e-06238224893771
Pubmed

Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction.

FOXP1 FOXP2

1.16e-06238215056695
Pubmed

Hybrid selection of transcribed sequences from microdissected DNA: isolation of genes within amplified region at 20q11-q13.2 in breast cancer.

NCOA3 NCOA6

1.16e-0623828758910
Pubmed

A de novo FOXP1 variant in a patient with autism, intellectual disability and severe speech and language impairment.

FOXP1 FOXP2

1.16e-06238225853299
Pubmed

FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.

FOXP1 FOXP2

1.16e-06238227224915
Pubmed

Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors.

FOXP1 FOXP2

1.16e-06238211358962
Pubmed

Equivalent missense variant in the FOXP2 and FOXP1 transcription factors causes distinct neurodevelopmental disorders.

FOXP1 FOXP2

1.16e-06238228741757
Pubmed

Compensation between FOXP transcription factors maintains proper striatal function.

FOXP1 FOXP2

1.16e-06238238761373
Pubmed

Common origin of the human synovial sarcoma associated SS18 and SS18L1 gene loci.

SS18 SS18L1

1.16e-06238216484776
Pubmed

Effects of a Levonorgestrel-Releasing Intrauterine System on the Expression of Steroid Receptor Coregulators in Adenomyosis.

NCOA2 NCOA3

1.16e-06238226040939
Pubmed

Identification and functional characterization of de novo FOXP1 variants provides novel insights into the etiology of neurodevelopmental disorder.

FOXP1 FOXP2

1.16e-06238226647308
Pubmed

Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension.

FOXP1 BMPR2 SMAD5

1.58e-062138323610558
Pubmed

Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates.

FOXP1 FOXP4 FOXP2

1.83e-062238332049024
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NCOA2 NCOA3 NCOA6 EP300

2.09e-068338428794006
Pubmed

Foxp2 and Foxp1 cooperatively regulate lung and esophagus development.

FOXP1 FOXP4 FOXP2

2.72e-062538317428829
Pubmed

Foxp transcription factors suppress a non-pulmonary gene expression program to permit proper lung development.

FOXP1 FOXP4 FOXP2

3.07e-062638327341756
Pubmed

Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.

EP300 SS18L1

3.48e-06338214716005
Pubmed

The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles.

NCOA2 NCOA3

3.48e-06338221035760
Pubmed

Distinctive functions of p160 steroid receptor coactivators in proliferation of an estrogen-independent, tamoxifen-resistant breast cancer cell line.

NCOA2 NCOA3

3.48e-06338221059860
Pubmed

The transcriptional co-activator p/CIP (NCoA-3) is up-regulated by STAT6 and serves as a positive regulator of transcriptional activation by STAT6.

NCOA3 EP300

3.48e-06338215145939
Pubmed

Prognostic value of novel biomarkers in astrocytic brain tumors: nuclear receptor co-regulators AIB1, TIF2, and PELP1 are associated with high tumor grade and worse patient prognosis.

NCOA2 NCOA3

3.48e-06338221735116
Pubmed

Absence of the steroid receptor coactivator-3 induces B-cell lymphoma.

NCOA2 NCOA3

3.48e-06338216675958
Pubmed

FLASH interacts with p160 coactivator subtypes and differentially suppresses transcriptional activity of steroid hormone receptors.

NCOA2 NCOA3

3.48e-06338215698540
Pubmed

Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene.

NCOA2 NCOA3

3.48e-0633829506940
Pubmed

Steroid receptor coactivators present a unique opportunity for drug development in hormone-dependent cancers.

NCOA2 NCOA3

3.48e-06338228390937
Pubmed

Estrogen signaling in colorectal carcinoma microenvironment: expression of ERbeta1, AIB-1, and TIF-2 is upregulated in cancer-associated myofibroblasts and correlates with disease progression.

NCOA2 NCOA3

3.48e-06338219277704
Pubmed

Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences.

NCOA2 NCOA3

3.48e-06338223927929
Pubmed

Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation.

NCOA2 NCOA3

3.48e-06338219052561
Pubmed

The MN1 oncoprotein synergizes with coactivators RAC3 and p300 in RAR-RXR-mediated transcription.

NCOA3 EP300

3.48e-06338212569362
Pubmed

Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors.

KMT2C NCOA6

3.48e-06338218372346
Pubmed

Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis.

KMT2C NCOA6

3.48e-06338221330447
Pubmed

Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators.

NCOA3 EP300

3.48e-06338211823864
Pubmed

Expression and significance of androgen receptor coactivators in urothelial carcinoma of the bladder.

NCOA2 NCOA3

3.48e-06338218845648
Pubmed

The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.

NCOA2 NCOA3

3.48e-06338212138202
Pubmed

AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor.

NCOA3 EP300

3.48e-06338210866661
Pubmed

Characterization of Foxp2 and Foxp1 mRNA and protein in the developing and mature brain.

FOXP1 FOXP2

3.48e-06338212687690
Pubmed

The nuclear receptor coactivators p300/CBP/cointegrator-associated protein (p/CIP) and transcription intermediary factor 2 (TIF2) differentially regulate PKA-stimulated transcriptional activity of steroidogenic factor 1.

NCOA2 NCOA3

3.48e-06338211923473
Pubmed

Structure and chromosomal locations of mouse steroid receptor coactivator gene family.

NCOA2 NCOA3

3.48e-06338210501088
Pubmed

Targeted disruption of the synovial sarcoma-associated SS18 gene causes early embryonic lethality and affects PPARBP expression.

SS18 SS18L1

3.48e-06338216926188
Pubmed

Mapping and characterization of the mouse and human SS18 genes, two human SS18-like genes and a mouse Ss18 pseudogene.

SS18 SS18L1

3.48e-06338211435705
Pubmed

Foxp1 expression is essential for sex-specific murine neonatal ultrasonic vocalization.

FOXP1 FOXP2

3.48e-06338228204507
Pubmed

The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism.

NCOA2 NCOA3

3.48e-06338216423883
Pubmed

Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.

FOXP1 FOXP4 FOXP2

3.87e-062838329365100
Pubmed

Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action.

NCOA2 NCOA3 EP300

3.87e-062838324880616
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

NCOA2 NCOA3 FOXP1 DACH2 CNOT2 EP300 SS18L1 SMAD5

3.96e-0687738820211142
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOA2 NCOA3 NCOA6 SS18 DYNC2H1 EP300 SS18L1

5.21e-0663838731182584
Pubmed

miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation.

NCOA2 NCOA3

6.96e-06438226066330
Pubmed

Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1).

NCOA3 EP300

6.96e-06438216227615
Pubmed

Targeting NSD2-mediated SRC-3 liquid-liquid phase separation sensitizes bortezomib treatment in multiple myeloma.

NCOA3 EP300

6.96e-06438233589584
Pubmed

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.

KMT2C EP300

6.96e-06438228398509
Pubmed

P160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain.

NCOA2 NCOA3

6.96e-06438218267973
Pubmed

Selective recruitment of p160 coactivators on glucocorticoid-regulated promoters in Schwann cells.

NCOA2 NCOA3

6.96e-06438215331759
Pubmed

Constitutive activation of transcription and binding of coactivator by estrogen-related receptors 1 and 2.

NCOA2 NCOA3

6.96e-06438210598588
InteractionEGR2 interactions

NCOA2 BCL9L NCOA3 KMT2C FOXP1 NCOA6 FOXP4 FOXP2 EP300 SS18L1

5.72e-131713810int:EGR2
InteractionSP7 interactions

NCOA2 BCL9L NCOA3 KMT2C FOXP1 NCOA6 FOXP4 SS18 RBM33 EP300 SS18L1

6.44e-123043811int:SP7
InteractionCRX interactions

NCOA2 BCL9L NCOA3 KMT2C FOXP1 FOXP4 FOXP2 SMAP2 EP300 SS18L1

2.94e-112543810int:CRX
InteractionTBR1 interactions

NCOA2 BCL9L NCOA3 KMT2C FOXP4 LATS1 FOXP2 EP300

3.23e-11113388int:TBR1
InteractionTBXT interactions

NCOA2 NCOA3 KMT2C FOXP1 NCOA6 SS18 EP300 SS18L1

3.99e-11116388int:TBXT
InteractionPAX9 interactions

NCOA2 BCL9L NCOA3 KMT2C FOXP1 NCOA6 FOXP4 EP300

1.00e-10130388int:PAX9
InteractionFEV interactions

NCOA2 NCOA3 KMT2C FOXP1 NCOA6 FOXP4 FOXP2 EP300 SS18L1

1.13e-10203389int:FEV
InteractionSOX7 interactions

NCOA2 NCOA3 KMT2C FOXP1 FOXP4 EP300 SMAD5

1.62e-1082387int:SOX7
InteractionGSC interactions

BCL9L NCOA3 KMT2C FOXP1 FOXP4 FOXP2 EP300

2.47e-1087387int:GSC
InteractionERG interactions

NCOA2 NCOA3 KMT2C FOXP1 NCOA6 FOXP4 SS18 EP300 SS18L1

2.61e-10223389int:ERG
InteractionPAX8 interactions

NCOA2 NCOA3 KMT2C FOXP1 FOXP4 EP300 SS18L1

1.39e-09111387int:PAX8
InteractionKLF5 interactions

NCOA2 NCOA3 KMT2C FOXP1 NCOA6 FOXP4 SS18 EP300

2.54e-09195388int:KLF5
InteractionPAX7 interactions

NCOA3 KMT2C FOXP1 FOXP4 SS18 EP300 SS18L1

3.03e-09124387int:PAX7
InteractionIRF4 interactions

NCOA3 KMT2C FOXP1 FOXP4 SS18 EP300

1.17e-0885386int:IRF4
InteractionSOX17 interactions

NCOA2 NCOA3 KMT2C NCOA6 FOXP4 SS18

2.29e-0895386int:SOX17
InteractionHNF4A interactions

NCOA2 NCOA3 KMT2C FOXP1 NCOA6 SS18 EP300 SS18L1

3.72e-08275388int:HNF4A
InteractionTLX3 interactions

NCOA2 BCL9L NCOA3 KMT2C FOXP1 NCOA6 FOXP4 EP300

5.76e-08291388int:TLX3
InteractionNR2F1 interactions

NCOA2 NCOA3 FOXP1 FOXP4 FOXP2

7.73e-0858385int:NR2F1
InteractionGCM1 interactions

NCOA3 KMT2C FOXP1 SS18 EP300

1.73e-0768385int:GCM1
InteractionFOXI1 interactions

NCOA3 KMT2C FOXP1 FOXP4 EP300

7.92e-0792385int:FOXI1
InteractionTLX1 interactions

NCOA2 NCOA3 KMT2C FOXP1 FOXP4 EP300

8.63e-07175386int:TLX1
InteractionNUP35 interactions

NCOA2 BCL9L NCOA3 KMT2C NCOA6 RBM33 CNOT2 EP300

1.01e-06424388int:NUP35
InteractionALG13 interactions

NCOA2 NCOA3 LATS1 SMAP2 RBM33 EP300

1.12e-06183386int:ALG13
InteractionC1orf94 interactions

UBQLN2 SMAP2 SS18L1 IPO11 UBQLN4

1.39e-06103385int:C1orf94
InteractionMYOD1 interactions

NCOA2 NCOA3 KMT2C SS18 EP300 SS18L1

1.57e-06194386int:MYOD1
InteractionFOS interactions

NCOA2 NCOA3 KMT2C NCOA6 SS18 EP300 SS18L1

1.67e-06312387int:FOS
InteractionASCL2 interactions

KMT2C NCOA6 EP300

1.75e-0613383int:ASCL2
InteractionBNC2 interactions

FOXP1 FOXP4 FOXP2

1.75e-0613383int:BNC2
InteractionGATA2 interactions

NCOA3 KMT2C FOXP1 NCOA6 SS18 EP300

1.82e-06199386int:GATA2
InteractionSMG7 interactions

NCOA2 NCOA3 NCOA6 LATS1 SMAP2 RBM33 CNOT2

1.93e-06319387int:SMG7
InteractionNR1I2 interactions

NCOA2 NCOA3 NCOA6 EP300

1.97e-0648384int:NR1I2
InteractionTOX interactions

FOXP1 FOXP4 FOXP2

2.22e-0614383int:TOX
InteractionNR1H3 interactions

NCOA3 NCOA6 EP300 SS18L1

4.24e-0658384int:NR1H3
InteractionPAX6 interactions

NCOA3 KMT2C FOXP1 NCOA6 EP300 SS18L1 SMAD5

4.78e-06366387int:PAX6
InteractionHIC2 interactions

FOXP1 FOXP4 FOXP2 EP300

5.19e-0661384int:HIC2
InteractionSOX15 interactions

NCOA2 NCOA3 FOXP1 FOXP4 EP300

6.51e-06141385int:SOX15
InteractionELF5 interactions

KMT2C SS18 EP300 SS18L1 UBQLN4

7.97e-06147385int:ELF5
InteractionBMP6 interactions

NCOA3 BMPR2 SMAD5

8.04e-0621383int:BMP6
InteractionETV4 interactions

NCOA2 NCOA3 SS18 EP300

8.51e-0669384int:ETV4
InteractionSOX6 interactions

NCOA2 NCOA3 FOXP1 FOXP4 RBM33

1.10e-05157385int:SOX6
InteractionWWTR1 interactions

NCOA2 SYNRG NCOA6 NOP58 CLINT1 LATS1 EP300

1.21e-05422387int:WWTR1
InteractionSOX5 interactions

FOXP1 FOXP4 FOXP2 RBM33 SMAD5

1.28e-05162385int:SOX5
InteractionTLE6 interactions

NCOA3 FOXP1 EP300

1.38e-0525383int:TLE6
InteractionRXRA interactions

NCOA2 NCOA3 NCOA6 EP300 UBQLN4

1.57e-05169385int:RXRA
InteractionRFX1 interactions

NCOA3 FOXP1 FOXP4 FOXP2

1.61e-0581384int:RFX1
InteractionGGA2 interactions

SYNRG CLINT1 UBQLN2 SMAP2

1.86e-0584384int:GGA2
InteractionPAX2 interactions

NCOA3 KMT2C FOXP1 FOXP4

1.95e-0585384int:PAX2
InteractionPPARG interactions

NCOA2 NCOA3 KMT2C NCOA6 NOP58 EP300

2.18e-05307386int:PPARG
InteractionETV1 interactions

NCOA2 NCOA3 EP300

2.18e-0529383int:ETV1
InteractionSS18 interactions

UBQLN2 SS18 EP300 SS18L1

2.24e-0588384int:SS18
InteractionLHX2 interactions

BCL9L KMT2C FOXP1 FOXP4 SS18

2.30e-05183385int:LHX2
InteractionJUN interactions

NCOA2 NCOA3 KMT2C NCOA6 CLINT1 EP300 XPO7

2.42e-05470387int:JUN
InteractionNFIA interactions

NCOA2 NCOA3 FOXP1 FOXP4 EP300

2.62e-05188385int:NFIA
InteractionPPARA interactions

NCOA2 NCOA3 NCOA6 EP300

2.67e-0592384int:PPARA
InteractionHNF1B interactions

NCOA2 NCOA3 KMT2C FOXP1 EP300

2.76e-05190385int:HNF1B
InteractionZBTB39 interactions

FOXP1 FOXP4 FOXP2

3.25e-0533383int:ZBTB39
InteractionSOX9 interactions

NCOA3 KMT2C NCOA6 EP300

3.28e-0597384int:SOX9
InteractionSOX13 interactions

FOXP1 FOXP4 FOXP2

3.88e-0535383int:SOX13
InteractionSOX2 interactions

NCOA2 BCL9L NCOA3 KMT2C FOXP1 NCOA6 FOXP4 NOP58 CLINT1 SS18 EP300

4.22e-0514223811int:SOX2
InteractionNFAT5 interactions

FOXP1 FOXP4 FOXP2

4.99e-0538383int:NFAT5
InteractionAGFG1 interactions

UBQLN2 FCGR2A SMAP2 IPO11

5.38e-05110384int:AGFG1
InteractionTHRA interactions

NCOA2 NCOA3 NCOA6 EP300

5.57e-05111384int:THRA
InteractionTFF1 interactions

NCOA3 EP300 UBQLN4

6.27e-0541383int:TFF1
InteractionSATB1 interactions

FOXP1 FOXP4 FOXP2 EP300

6.61e-05116384int:SATB1
InteractionTSACC interactions

FOXP2 DTNB

7.23e-057382int:TSACC
InteractionGDF6 interactions

BMPR2 SMAD5

7.23e-057382int:GDF6
InteractionAR interactions

NCOA2 BCL9L NCOA3 KMT2C FOXP1 NCOA6 FOXP4 RBM33 EP300

7.32e-05992389int:AR
InteractionCEBPA interactions

NCOA2 NCOA3 KMT2C FOXP1 NCOA6 NOP58 CLINT1 RBM33 EP300 IPO11

7.51e-0512453810int:CEBPA
InteractionSMAD2 interactions

NCOA3 KMT2C FOXP1 NCOA6 EP300 SMAD5

7.70e-05385386int:SMAD2
InteractionGGA1 interactions

SYNRG CLINT1 SMAP2 DTNB

7.79e-05121384int:GGA1
InteractionRORC interactions

NCOA3 NCOA6 EP300

8.31e-0545383int:RORC
InteractionEYA4 interactions

NCOA2 NCOA3 UBQLN2 RBM33 EP300

8.87e-05243385int:EYA4
InteractionMOAP1 interactions

LATS1 UBQLN2 UBQLN4

8.88e-0546383int:MOAP1
InteractionVDR interactions

NCOA2 NCOA3 NCOA6 EP300

9.40e-05127384int:VDR
InteractionCREBBP interactions

NCOA2 NCOA3 NCOA6 MAML2 LATS1 EP300 SS18L1

1.12e-04599387int:CREBBP
InteractionMTNR1B interactions

KMT2C UBQLN2 DYNC2H1 UBQLN4

1.19e-04135384int:MTNR1B
InteractionPMEPA1 interactions

LATS1 UBQLN2 UBQLN4

1.21e-0451383int:PMEPA1
InteractionEID1 interactions

NCOA2 SCAF11 EP300

1.21e-0451383int:EID1
InteractionDYNLL2 interactions

KMT2C NCOA6 CLINT1 DYNC2H1 UBQLN4

1.29e-04263385int:DYNLL2
InteractionNCOR2 interactions

NCOA3 FOXP1 NCOA6 CNOT2 EP300

1.31e-04264385int:NCOR2
InteractionNR2F2 interactions

FOXP1 FOXP4 FOXP2 EP300

1.33e-04139384int:NR2F2
InteractionTGFB1I1 interactions

UBQLN2 EP300 UBQLN4

1.36e-0453383int:TGFB1I1
InteractionNCOA2 interactions

NCOA2 NCOA3 NCOA6 EP300

1.41e-04141384int:NCOA2
InteractionMEF2C interactions

NCOA2 NCOA3 EP300

1.44e-0454383int:MEF2C
InteractionNFIB interactions

NCOA3 KMT2C FOXP1 FOXP4

1.45e-04142384int:NFIB
InteractionFAM168A interactions

LATS1 UBQLN2 SMAP2 SS18L1

1.45e-04142384int:FAM168A
InteractionZNF148 interactions

FOXP1 FOXP4 FOXP2 EP300

1.53e-04144384int:ZNF148
InteractionAMY2B interactions

LATS1 UBQLN2

1.54e-0410382int:AMY2B
InteractionNCOA6 interactions

NCOA2 KMT2C NCOA6 EP300

1.57e-04145384int:NCOA6
InteractionAP1S2 interactions

SYNRG NOP58 CLINT1

1.60e-0456383int:AP1S2
InteractionNCOA1 interactions

NCOA2 NCOA3 NCOA6 EP300

1.61e-04146384int:NCOA1
InteractionYWHAH interactions

NCOA2 NCOA3 SYNRG NCOA6 PTPN4 CLINT1 LATS1 SMAP2 LYST

1.63e-041102389int:YWHAH
InteractionSMAD3 interactions

NCOA3 NCOA6 EP300 SS18L1 SMAD5 UBQLN4

1.74e-04447386int:SMAD3
InteractionAP1G1 interactions

SYNRG CLINT1 SMAP2 EP300

1.79e-04150384int:AP1G1
InteractionPLAAT3 interactions

UBQLN2 UBQLN4

1.88e-0411382int:PLAAT3
InteractionSMARCE1 interactions

NCOA2 NCOA3 SS18 EP300 SS18L1

1.93e-04287385int:SMARCE1
InteractionEP300 interactions

NCOA2 NCOA3 NCOA6 NOP58 CLINT1 MAML2 SS18 EP300 SS18L1 SMAD5

2.00e-0414013810int:EP300
InteractionKLF15 interactions

NCOA2 NCOA3 KMT2C FOXP4 EP300

2.03e-04290385int:KLF15
InteractionCEBPD interactions

NCOA3 FOXP1 EP300

2.17e-0462383int:CEBPD
InteractionFDCSP interactions

SCAF11 UBQLN2

2.26e-0412382int:FDCSP
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA2 NCOA3 EP300

1.77e-0617263486
GeneFamilyUbiquilin family

UBQLN2 UBQLN4

1.98e-055262783
GeneFamilyForkhead boxes

FOXP1 FOXP4 FOXP2

3.14e-0543263508
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DTNB EP300

3.00e-041826291
GeneFamilyAtaxins|Trinucleotide repeat containing

NCOA3 FOXP2

5.85e-0425262775
GeneFamilyBasic helix-loop-helix proteins

NCOA2 NCOA3

1.08e-02110262420
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

NCOA3 SYNRG KMT2C PTPN4 SCAF11 LATS1 SMAP2 RBM33 LYST CNOT2 EP300

5.66e-0614923811M40023
CoexpressionLAKE_ADULT_KIDNEY_C13_THICK_ASCENDING_LIMB

NCOA2 PTPN4 MAML2 FOXP2

3.86e-05131384M39232
CoexpressionAIZARANI_LIVER_C34_MHC_II_POS_B_CELLS

NCOA3 FOXP1 SMAP2 LYST

4.21e-05134384M39133
CoexpressionQI_PBMC_ZOSTAVAX_AGE_50_75YO_CORRELATED_WITH_CONTRACTION_OF_VZV_SPECIFIC_T_CELLS_PEAK_TO_28DY_AT_1DYPOSITIVE

NCOA6 SCAF11 CLINT1 SMAP2 RBM33

6.36e-05294385M40873
CoexpressionGRESHOCK_CANCER_COPY_NUMBER_UP

NCOA2 MAML2 SS18 EP300 SS18L1

9.91e-05323385M9150
CoexpressionXIE_TRASTUZUMAB_CARDIOTOXICITY_MMU_MIR_483_5P_GENES

BCL9L FOXP4

1.12e-0411382MM17503
CoexpressionGSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_DN

SYNRG KMT2C BMPR2 DTNB

1.32e-04180384M8906
CoexpressionGSE9960_HEALTHY_VS_SEPSIS_PBMC_DN

FOXP4 LATS1 UBQLN2 NLGN4Y

1.50e-04186384M7127
CoexpressionKASLER_HDAC7_TARGETS_1_UP

NCOA2 NCOA3 ARHGAP27 SMAP2

1.70e-04192384M2317
CoexpressionKASLER_HDAC7_TARGETS_1_UP

NCOA2 NCOA3 ARHGAP27 SMAP2

1.76e-04194384MM910
CoexpressionGSE41867_DAY6_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_DN

SYNRG NCOA6 SS18 CNOT2

1.98e-04200384M9490
CoexpressionGSE41867_NAIVE_VS_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN

NCOA3 SYNRG FOXP1 RBM33

1.98e-04200384M9469
CoexpressionGSE14000_4H_VS_16H_LPS_DC_DN

NCOA6 SS18 SMAP2 LYST

1.98e-04200384M3355
CoexpressionGSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP

SCAF11 CNOT2 IPO11 XPO7

1.98e-04200384M8497
CoexpressionGSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_30H_UP

NOP58 LYST DTNB CNOT2

1.98e-04200384M9649
CoexpressionOSMAN_BLADDER_CANCER_UP

KMT2C SCAF11 UBQLN2 LYST SMAD5

2.74e-04402385M5275
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP1 SCAF11 CLINT1 LYST EP300

4.62e-07182385f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP1 SCAF11 CLINT1 LYST EP300

4.87e-071843851154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP1 SCAF11 CLINT1 LYST EP300

5.01e-071853857adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

NCOA2 KMT2C MAML2 FOXP2 DTNB

7.18e-0719938594b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

NCOA2 SCAF11 BMPR2 EP300

1.87e-0518638403db813598b67b1e08f759758a1c2023396921fa
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

NCOA2 PTPN4 MAML2 FOXP2

1.99e-05189384830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

MAML2 FOXP2 RBMS3 DYNC2H1

2.03e-0519038412992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

MAML2 FOXP2 RBMS3 NLGN4Y

2.08e-05191384d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

MAML2 FOXP2 RBMS3 DYNC2H1

2.08e-0519138470c067c54084bfb02c29bab085f4defd477194fb
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

MAML2 FOXP2 RBMS3 DYNC2H1

2.12e-05192384356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

CFAP43 TMEM232 FOXP2 DYNC2H1

2.12e-05192384354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NCOA2 KMT2C FOXP1 MAML2

2.16e-05193384779276e775cb2492e8dd36436295a536084a6415
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

MAML2 FOXP2 RBMS3 DYNC2H1

2.16e-05193384dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP43 TMEM232 FOXP2 DYNC2H1

2.21e-05194384958e648138676d46698090b4046cb484083ae449
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP43 TMEM232 FOXP2 DYNC2H1

2.25e-05195384fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

MAML2 FOXP2 RBMS3 DYNC2H1

2.25e-05195384ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP43 TMEM232 FOXP2 DYNC2H1

2.25e-05195384eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

CFAP43 TMEM232 FOXP2 DYNC2H1

2.25e-0519538421dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

MAML2 FOXP2 RBMS3 DYNC2H1

2.25e-05195384f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

CFAP43 TMEM232 FOXP2 DYNC2H1

2.30e-0519638487d9881cfec461a5d89b688a83749b618c519485
ToppCellcritical|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAML2 FCGR2A LYST IPO11

2.44e-0519938416c55cb8a0e740342009965f0eddfb0ed2858fab
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KMT2C FOXP1 BMPR2 SMAD5

2.48e-05200384dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP43 MAML2 FOXP2

2.16e-041373830aa4e14b32da0cda677cc0ed6ae470f6ecd77bea
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FOXP1 MAML2 RBMS3

2.98e-041533837518187a5fbf6c0881182dc79bd37c2d49f92b2e
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FOXP1 MAML2 RBMS3

2.98e-0415338393d36723f01c2df39feebf20f3eba5b4fb4cdf59
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

KMT2C FOXP1 MAML2

3.16e-041563831545169694f686d28648a68b552c2ae606599d66
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CFAP43 TMEM232 DYNC2H1

3.65e-04164383fd30c55d0d75ef8b9396435d836187168095152b
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

CFAP43 TMEM232 DYNC2H1

3.85e-0416738326cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

MAML2 FOXP2 RBMS3

3.99e-041693836373562ab3b1765060212a6a53d6543e7e942e80
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAML2 RBMS3 DYNC2H1

3.99e-04169383c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP43 TMEM232 DYNC2H1

3.99e-04169383fba841664939c771881ba97f14ef1df6635c04ff
ToppCellSevere-B_naive-11|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FOXP1 SMAP2 LYST

4.13e-041713837c2699f19ca38414447a286f7658f507882d57c2
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

BCL9L NCOA3 CLINT1

4.13e-04171383adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCellCiliated_cells-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

CFAP43 TMEM232 DYNC2H1

4.20e-04172383187ae91148d293537afc77e10da2b64302322224
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP43 TMEM232 DYNC2H1

4.27e-04173383c3762655caa79ac4879876f470d32578a3c93b01
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP43 TMEM232 DACH2

4.34e-04174383f1510b0f7771936adf29ae3572feab55db31832b
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP43 TMEM232 DACH2

4.34e-041743835d5d2fc60afff47f997751e8e9ca1367a22d19ec
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAML2 DACH2 RBMS3

4.41e-041753831799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

NCOA3 LYST NLGN4Y

4.49e-041763833de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCAF11 BMPR2 LYST

4.49e-04176383749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP43 TMEM232 DYNC2H1

4.56e-04177383aef050784abbba45c4ab4e8328339c8739c5c453
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

NCOA3 LYST NLGN4Y

4.56e-0417738382fdd6185b368f54f03de389427cbe3071d21a99
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCAF11 BMPR2 LYST

4.64e-0417838301dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-B_cell-B_cell|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCOA3 SMAP2 EP300

4.72e-04179383fad1fbee002fcd424c03460d695559060ce41a3f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-B_cell|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCOA3 SMAP2 EP300

4.72e-041793836d4e4b64e633b2ae8514ffa1e45829d6508dac54
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-B_cell-B_cell-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCOA3 SMAP2 EP300

4.72e-0417938361a7cc01fae4115325fce0efaa5bacf8f9af5ba2
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP43 TMEM232 DYNC2H1

4.72e-041793835e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

MAML2 FOXP2 RBMS3

4.72e-04179383dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellLPS-IL1RA+antiTNF-Myeloid-Neutrophils|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FCGR2A SMAP2 LYST

4.95e-04182383243c783675df495ea4112dbf710712c44ea6b4f1
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP1 SCAF11 LYST

4.95e-04182383eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCellLPS-IL1RA+antiTNF-Myeloid-Neutrophils-Neutrophils|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FCGR2A SMAP2 LYST

4.95e-0418238318790a394dc32b3cef99cdbf826392c520e38b4a
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CFAP43 TMEM232 DYNC2H1

4.95e-04182383e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP1 SCAF11 LYST

5.03e-0418338328cbf909424f3be4491d49832f0aca0386560814
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP1 SCAF11 LYST

5.03e-041833833fa608aa6b119869ec3280dc388dfee57160e63a
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP43 TMEM232 DYNC2H1

5.11e-041843832df903924df9cb71039159416bcbe6a6614e21fe
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP43 TMEM232 DYNC2H1

5.19e-041853835e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP43 TMEM232 DYNC2H1

5.19e-04185383f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMPR2 LYST IPO11

5.27e-041863830ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP43 TMEM232 DYNC2H1

5.27e-0418638376033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP43 MAML2 FOXP2

5.27e-041863835c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP43 TMEM232 DYNC2H1

5.36e-041873832b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

MAML2 FOXP2 RBMS3

5.36e-041873834ea486991f66c29728d127171a07b81404ec0b78
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP43 TMEM232 DYNC2H1

5.36e-04187383e61992de4f98eeea08b43213850769d923f8db48
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FCGR2A SMAP2 LYST

5.44e-041883834e27ada1bda88811b73376c8a6136cbfc83bfdb9
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFAP43 TMEM232 DYNC2H1

5.44e-04188383da59b5c0a4b11690a39a964c1a0a83e66aa0972b
ToppCellcontrol-Myeloid-Neutrophils_4|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KLF17 FCGR2A SMAP2

5.44e-0418838322d76c222fb0e3da08e10191af0090f14e03f2ad
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

CFAP43 TMEM232 DYNC2H1

5.44e-041883836833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCell(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CFAP43 TMEM232 DYNC2H1

5.44e-041883835ba5cbb403518026e9040379fb5d99339ea977d8
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

CFAP43 TMEM232 DYNC2H1

5.44e-04188383803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFAP43 TMEM232 DYNC2H1

5.44e-0418838382c006f43c93f4a867953a446864f02b44536a23
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BCL9L PTPN4 MAML2

5.52e-04189383e9df7ecd36bee1fedce23bb188c68a94fa60462c
ToppCellControl-Myeloid-Monocytes|Control / group, cell type (main and fine annotations)

FCGR2A SMAP2 LYST

5.52e-041893833335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMPR2 LYST IPO11

5.52e-041893838e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

FOXP1 BMPR2 RBMS3

5.52e-0418938375c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFAP43 TMEM232 DYNC2H1

5.52e-0418938357ab947b81dbd9d3e896be89e28c4a62cf720837
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFAP43 TMEM232 DYNC2H1

5.52e-04189383ebc16b8eab84167d74446783d7e802acedc6b9c6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP43 MAML2 FOXP2

5.52e-04189383904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellIPF-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

NCOA2 SMAP2 LYST

5.52e-041893835c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP43 TMEM232 DYNC2H1

5.52e-041893833e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMPR2 LYST IPO11

5.52e-04189383fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCAF11 NOP58 CLINT1

5.61e-0419038336e83995021ba16690f84e2077a9e8baec547d05
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|343B / Donor, Lineage, Cell class and subclass (all cells)

CFAP43 TMEM232 DYNC2H1

5.61e-04190383169e600e95878000acf5d11f813f9028c7249646
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|343B / Donor, Lineage, Cell class and subclass (all cells)

CFAP43 TMEM232 DYNC2H1

5.61e-041903830cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCAF11 NOP58 CLINT1

5.61e-04190383d26be9e1b676f750e716b91ebc3598fac3735612
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SYNRG SMAD5 UBQLN4

5.61e-04190383651a1d3ae286e40f9d9f60e438211c6148d24143
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR2A SMAP2 LYST

5.69e-0419138347156e5f1d790707f42f6283104a44b33af613e5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLINT1 FOXP2 NLGN4Y

5.69e-041913835a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP43 MAML2 FOXP2

5.69e-04191383d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLINT1 FOXP2 NLGN4Y

5.69e-0419138355ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOP58 BMPR2 RBMS3

5.69e-041913837d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell10x5'-Lung-Myeloid_Monocytic-Nonclassical_monocytes|Lung / Manually curated celltypes from each tissue

ARHGAP27 SMAP2 LYST

5.69e-04191383a862a571625ab7238589ff201e5954f602c3bd7e
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP43 TMEM232 DYNC2H1

5.69e-041913831c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

MAML2 RBMS3 DYNC2H1

5.78e-0419238360b1312e84f6d6448365a952469c506c00b5fe93
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

CFAP43 TMEM232 FOXP2

5.78e-041923830644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP43 TMEM232 DYNC2H1

5.78e-041923836c269d2426f76559d2ed3bf2169eb4be5fc7ad6d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FOXP1 MAML2 SMAP2

5.78e-04192383348d39da3016dc6dbfa65d108e5def35aa7f19dd
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP43 TMEM232 DYNC2H1

5.78e-04192383d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

KMT2C FOXP1 MAML2

5.78e-0419238347646d7e4990be85072987f92bf18d52f8da752e
ToppCellBronchial_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP43 TMEM232 DYNC2H1

5.87e-041933833e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP43 TMEM232 DYNC2H1

5.87e-04193383e1b76102f812c433195d1e8811fdd3293a7bc22e
Drugstanolone benzoate

FOXP1 FOXP2

8.13e-063382ctd:C040109
Drugglutamin

NCOA3 FOXP1 NOP58 UBQLN2 FOXP2 EP300 UBQLN4

9.77e-06461387CID000000738
DrugPicrotoxinin [17617-45-7]; Down 200; 13.6uM; HL60; HT_HG-U133A

NCOA3 CLINT1 SS18 LYST XPO7

1.46e-051883852161_DN
Drugperfluoroundecanoic acid

NCOA2 LYST

1.62e-054382CID000077221
DrugCefixime [79350-37-1]; Down 200; 8.8uM; HL60; HT_HG-U133A

NCOA2 NCOA3 PTPN4 DYNC2H1 XPO7

1.70e-051943851310_DN
DrugTCPOBOP

NCOA2 NCOA6 FOXP2 EP300

1.88e-0595384CID000005382
Drugbutamben

NCOA2 NCOA3

4.05e-056382ctd:C004605
Drug1-(2-chloroethyl)-1-nitrosourea

PTPN4 LYST DTNB

4.71e-0542383CID000075394
Diseasespecific developmental disorder (implicated_via_orthology)

FOXP1 FOXP4 FOXP2

7.87e-094383DOID:0060038 (implicated_via_orthology)
Diseaseamyotrophic lateral sclerosis type 15 (implicated_via_orthology)

UBQLN2 UBQLN4

4.84e-063382DOID:0060206 (implicated_via_orthology)
Diseasesevere acute respiratory syndrome, COVID-19

NCOA2 PTPN4 MAML2 DACH2 LYST DTNB

2.14e-05447386EFO_0000694, MONDO_0100096
Diseaseprostate cancer (is_marker_for)

NCOA2 NCOA3 KMT2C EP300

4.82e-05156384DOID:10283 (is_marker_for)
Diseasefrontotemporal dementia (implicated_via_orthology)

UBQLN2 UBQLN4

1.06e-0412382DOID:9255 (implicated_via_orthology)
DiseaseCrohn's disease

FOXP1 FOXP2 FCGR2A RBMS3 DTNB

2.44e-04441385EFO_0000384
Diseaseacute lymphoblastic leukemia, response to antineoplastic agent

NCOA3 MAML2

2.72e-0419382EFO_0000220, GO_0097327
Diseasecumulative dose response to bevacizumab

PTPN4 MAML2

2.72e-0419382EFO_0005944
DiseaseAdenoid Cystic Carcinoma

KMT2C FOXP2 EP300

2.92e-04100383C0010606
DiseaseMalignant neoplasm of breast

NCOA2 NCOA3 NCOA6 FOXP4 BMPR2 DYNC2H1 EP300

3.90e-041074387C0006142
Diseasechildhood trauma measurement

FOXP1 FOXP2

4.38e-0424382EFO_0007979
DiseaseCerebral Astrocytoma

NCOA3 LATS1

4.75e-0425382C0750935
DiseaseIntracranial Astrocytoma

NCOA3 LATS1

4.75e-0425382C0750936
DiseasePilocytic Astrocytoma

NCOA3 LATS1

4.75e-0425382C0334583
DiseaseAstrocytoma

NCOA3 LATS1

4.75e-0425382C0004114
DiseaseJuvenile Pilocytic Astrocytoma

NCOA3 LATS1

4.75e-0425382C0280783
DiseaseDiffuse Astrocytoma

NCOA3 LATS1

4.75e-0425382C0280785
DiseaseGrade I Astrocytoma

NCOA3 LATS1

4.75e-0425382C1704230
DiseaseSubependymal Giant Cell Astrocytoma

NCOA3 LATS1

4.75e-0425382C0205768
DiseaseMixed oligoastrocytoma

NCOA3 LATS1

4.75e-0425382C0547065
DiseaseChildhood Cerebral Astrocytoma

NCOA3 LATS1

4.75e-0425382C0338070
DiseaseGemistocytic astrocytoma

NCOA3 LATS1

5.15e-0426382C0334581
DiseaseProtoplasmic astrocytoma

NCOA3 LATS1

5.15e-0426382C0334580
DiseaseFibrillary Astrocytoma

NCOA3 LATS1

5.15e-0426382C0334582
DiseaseMammary Carcinoma, Human

NCOA2 NCOA3 BMPR2 DYNC2H1 EP300

5.41e-04525385C4704874
DiseaseMammary Neoplasms, Human

NCOA2 NCOA3 BMPR2 DYNC2H1 EP300

5.41e-04525385C1257931
DiseaseMammary Neoplasms

NCOA2 NCOA3 BMPR2 DYNC2H1 EP300

5.50e-04527385C1458155
DiseaseAnaplastic astrocytoma

NCOA3 LATS1

5.55e-0427382C0334579
DiseaseBreast Carcinoma

NCOA2 NCOA3 BMPR2 DYNC2H1 EP300

6.04e-04538385C0678222
Diseaseselenium measurement

DYNC2H1 IPO11

6.41e-0429382EFO_0006331
Diseaseamyotrophic lateral sclerosis (implicated_via_orthology)

UBQLN2 UBQLN4

6.87e-0430382DOID:332 (implicated_via_orthology)
DiseaseC-reactive protein measurement

FOXP1 NCOA6 SCAF11 NOP58 BMPR2 LATS1 DTNB

7.77e-041206387EFO_0004458
Diseaseneurodegenerative disease (implicated_via_orthology)

LATS1 UBQLN2 UBQLN4

8.64e-04145383DOID:1289 (implicated_via_orthology)
Diseasealcohol consumption measurement

NCOA2 FOXP1 SCAF11 ARHGAP27 RBMS3 EP300 XPO7

9.24e-041242387EFO_0007878
Diseaseneuroticism measurement

UBQLN2 ARHGAP27 FOXP2 RBMS3 SS18 IPO11

9.99e-04909386EFO_0007660
DiseaseCarcinoma, Transitional Cell

KMT2C EP300

1.28e-0341382C0007138
Diseasesystemic lupus erythematosus (implicated_via_orthology)

FCGR2A EP300

1.41e-0343382DOID:9074 (implicated_via_orthology)
DiseaseAMYOTROPHIC LATERAL SCLEROSIS 1

SS18L1 UBQLN4

1.90e-0350382C1862939
DiseaseAdenocarcinoma of lung (disorder)

NOP58 LATS1 EP300

2.36e-03206383C0152013
Diseaseinsomnia measurement

FOXP1 FOXP2 EP300 SMAD5

2.47e-03443384EFO_0007876

Protein segments in the cluster

PeptideGeneStartEntry
NMLPNAAGMVPVSMN

EP300

656

Q09472
SQPGMDVNQMSFNPM

CFAP43

151

Q8NDM7
MTMETQMSQNVCPRN

FCGR2A

1

P12318
VSLPPASVAMAMNQM

DACH2

326

Q96NX9
TSQNVSKRPMQQMQP

RBM33

686

Q96EV2
SMQPANMMGPLTQQM

RBMS3

326

Q6XE24
TMRDQRAMMIQTPSQ

PTPN4

886

P29074
QNRMMAIAPNVTVMV

NOP58

276

Q9Y2X3
QQCAMAPPTMMPSVQ

KMT2C

3271

Q8NEZ4
NMQQPMNVMTQSFGA

CLINT1

511

Q14677
PQSMMVPNRNSHNME

LATS1

406

O95835
MMQTLQGPTNVEDMN

IPO11

431

Q9UI26
VAMMTPQVITPQQMQ

FOXP2

91

O15409
MMTPQVITPQQMQQI

FOXP1

101

Q9H334
AMMSPQMLTPQQMQQ

FOXP4

106

Q8IVH2
TPAVQMRPMNQMSQT

MAML2

1021

Q8IZL2
MRPMNQMSQTLNGQT

MAML2

1026

Q8IZL2
SRAQLMPQGQMMVNP

NCOA6

651

Q14686
QMMPDVSIQQTNMVP

NCOA6

816

Q14686
QRMPMQQSGSVPVMV

NCOA6

1066

Q14686
PNTITMIPNTLMGMQ

NLGN4Y

776

Q8NFZ3
SIDQQMIQSQRPMML

DYNC2H1

626

Q8NCM8
MSPPQGLMTQQNFML

BCL9L

1421

Q86UU0
PTVNPMSTAMQNERN

BMPR2

516

Q13873
PRPLTNMNDTMVSHM

DTNB

336

O60941
MMQRRMSQENPSQAT

LYST

2621

Q99698
MIYCQRMSPPQQEMT

KLF17

111

Q5JT82
SQLPINMMQPQMNVM

SCAF11

1201

Q99590
QQQGFPMVSVMQPNM

SYNRG

46

Q9UMZ2
MSMSPNQGLQMPSSR

NCOA3

401

Q9Y6Q9
MRPMMQPQVSSQQGF

NCOA3

1206

Q9Y6Q9
ETSMPMTMVFQNQVV

ARHGAP27

861

Q6ZUM4
MDTSNNMIPQIMPSI

SMAD5

241

Q99717
ILPMNPRNMMNHSQV

CNOT2

131

Q9NZN8
RTNINMQSNPVSMMQ

SS18L1

176

O75177
MQSNPVSMMQQQAAT

SS18L1

181

O75177
MSPRMAHTQSPMMQQ

NCOA2

1326

Q15596
TPQMPTQAMFMAPAQ

SMAP2

276

Q8WU79
MNMPVNKSPMINTCG

TMEM232

1

C9JQI7
QSMPVQNQMTMSQGQ

SS18

171

Q15532
IMQQHPEMIQQMLST

XPO7

971

Q9UIA9
MSNPRAMQALMQIQQ

UBQLN2

446

Q9UHD9
QRQLMSNPEMLSQIM

UBQLN4

186

Q9NRR5