Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH1 MYH8 MYH11 MYO1A DNAH17 KIF5A	2.79e-06	118	67	6	GO:0003774
GeneOntologyMolecularFunction	ATP-dependent activity	HSPD1 MYH1 MYH8 MYH11 DDX46 MYO1A DNAH17 RNF213 CHD9 KIF5A TOP2A	5.72e-06	614	67	11	GO:0140657
GeneOntologyMolecularFunction	microfilament motor activity	MYH1 MYH8 MYH11 MYO1A	7.84e-06	38	67	4	GO:0000146
GeneOntologyMolecularFunction	calmodulin binding	MYH1 MYH8 MYH11 MYO1A SYT1 CAMSAP2 RYR3	1.19e-05	230	67	7	GO:0005516
GeneOntologyMolecularFunction	promoter-enhancer loop anchoring activity	PCBP2 AHDC1	2.30e-04	7	67	2	GO:0140585
GeneOntologyMolecularFunction	cytoskeletal protein binding	MYH1 MYH8 MYH11 MAP7D3 MYO1A XIRP2 ARHGEF10 MAPT FSD1 KIF5A SNCG CAMSAP2	2.63e-04	1099	67	12	GO:0008092
GeneOntologyMolecularFunction	chromatin loop anchoring activity	PCBP2 AHDC1	3.07e-04	8	67	2	GO:0140587
GeneOntologyMolecularFunction	DNA-DNA tethering activity	PCBP2 AHDC1	3.93e-04	9	67	2	GO:0106260
GeneOntologyMolecularFunction	chromatin binding	KDM5A GLYR1 SUPT16H CBX3 PCBP2 TASOR HMGN4 AHDC1 TOP2A	7.77e-04	739	67	9	GO:0003682
GeneOntologyMolecularFunction	actin filament binding	MYH1 MYH8 MYH11 MYO1A XIRP2	9.89e-04	227	67	5	GO:0051015
GeneOntologyCellularComponent	muscle myosin complex	MYH1 MYH8 MYH11	1.63e-05	16	66	3	GO:0005859
GeneOntologyCellularComponent	myosin complex	MYH1 MYH8 MYH11 MYO1A	3.62e-05	59	66	4	GO:0016459
GeneOntologyCellularComponent	myosin filament	MYH1 MYH8 MYH11	6.58e-05	25	66	3	GO:0032982
GeneOntologyCellularComponent	supramolecular fiber	MYH1 MYH8 MYH11 MYO1A XIRP2 DSP MAPT AHNAK DNAH17 FSD1 KIF5A CAMSAP2 RYR3	6.82e-05	1179	66	13	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	MYH1 MYH8 MYH11 MYO1A XIRP2 DSP MAPT AHNAK DNAH17 FSD1 KIF5A CAMSAP2 RYR3	7.31e-05	1187	66	13	GO:0099081
GeneOntologyCellularComponent	myosin II complex	MYH1 MYH8 MYH11	9.31e-05	28	66	3	GO:0016460
GeneOntologyCellularComponent	contractile muscle fiber	MYH1 MYH8 MYH11 XIRP2 AHNAK RYR3	3.06e-04	290	66	6	GO:0043292
GeneOntologyCellularComponent	clathrin-sculpted glutamate transport vesicle membrane	OTOF SYT1	3.48e-04	9	66	2	GO:0060203
GeneOntologyCellularComponent	clathrin-sculpted glutamate transport vesicle	OTOF SYT1	3.48e-04	9	66	2	GO:0060199
GeneOntologyCellularComponent	clathrin-sculpted vesicle	OTOF SYT1	1.14e-03	16	66	2	GO:0060198
GeneOntologyCellularComponent	myofibril	MYH1 MYH8 XIRP2 AHNAK RYR3	1.71e-03	273	66	5	GO:0030016
HumanPheno	Snoring	PLCB4 GPR101 AHDC1	2.78e-06	7	23	3	HP:0025267
Domain	IQ	MYH1 MYH8 MYH11 MYO1A SCN4A	3.47e-06	71	61	5	PF00612
Domain	IQ	MYH1 MYH8 MYH11 MYO1A SCN4A	6.66e-06	81	61	5	SM00015
Domain	Myosin_head_motor_dom	MYH1 MYH8 MYH11 MYO1A	6.99e-06	38	61	4	IPR001609
Domain	MYOSIN_MOTOR	MYH1 MYH8 MYH11 MYO1A	6.99e-06	38	61	4	PS51456
Domain	Myosin_head	MYH1 MYH8 MYH11 MYO1A	6.99e-06	38	61	4	PF00063
Domain	MYSc	MYH1 MYH8 MYH11 MYO1A	6.99e-06	38	61	4	SM00242
Domain	IQ_motif_EF-hand-BS	MYH1 MYH8 MYH11 MYO1A SCN4A	1.12e-05	90	61	5	IPR000048
Domain	IQ	MYH1 MYH8 MYH11 MYO1A SCN4A	1.31e-05	93	61	5	PS50096
Domain	Myosin_N	MYH1 MYH8 MYH11	1.47e-05	15	61	3	PF02736
Domain	Myosin_N	MYH1 MYH8 MYH11	1.47e-05	15	61	3	IPR004009
Domain	Myosin_tail_1	MYH1 MYH8 MYH11	2.61e-05	18	61	3	PF01576
Domain	Myosin_tail	MYH1 MYH8 MYH11	2.61e-05	18	61	3	IPR002928
Domain	Myosin-like_IQ_dom	MYH1 MYH8 MYH11	3.09e-05	19	61	3	IPR027401
Domain	-	MYH1 MYH8 MYH11	3.09e-05	19	61	3	4.10.270.10
Domain	DH_1	ARHGEF10 ARHGEF26 ARHGEF17	1.15e-03	63	61	3	PS00741
Domain	RhoGEF	ARHGEF10 ARHGEF26 ARHGEF17	1.43e-03	68	61	3	SM00325
Domain	RhoGEF	ARHGEF10 ARHGEF26 ARHGEF17	1.55e-03	70	61	3	PF00621
Domain	DH_2	ARHGEF10 ARHGEF26 ARHGEF17	1.55e-03	70	61	3	PS50010
Domain	DH-domain	ARHGEF10 ARHGEF26 ARHGEF17	1.62e-03	71	61	3	IPR000219
Domain	-	ARHGEF10 ARHGEF26 ARHGEF17	1.62e-03	71	61	3	1.20.900.10
Domain	Chromo_domain	CBX3 CHD9	2.77e-03	24	61	2	IPR023780
Domain	Chromo	CBX3 CHD9	3.24e-03	26	61	2	PF00385
Domain	AT_hook	GLYR1 AHDC1	3.49e-03	27	61	2	SM00384
Domain	AT_hook_DNA-bd_motif	GLYR1 AHDC1	3.49e-03	27	61	2	IPR017956
Domain	CHROMO_1	CBX3 CHD9	3.76e-03	28	61	2	PS00598
Domain	CHROMO_2	CBX3 CHD9	3.76e-03	28	61	2	PS50013
Domain	Chromodomain-like	CBX3 CHD9	4.89e-03	32	61	2	IPR016197
Domain	Chromo/shadow_dom	CBX3 CHD9	5.19e-03	33	61	2	IPR000953
Domain	CHROMO	CBX3 CHD9	5.19e-03	33	61	2	SM00298
Domain	P-loop_NTPase	MYH1 MYH8 MYH11 DDX46 MYO1A RNF213 CHD9 KIF5A	6.11e-03	848	61	8	IPR027417
Domain	Ion_trans_dom	SLC9C1 SCN4A RYR3	6.16e-03	114	61	3	IPR005821
Domain	Ion_trans	SLC9C1 SCN4A RYR3	6.16e-03	114	61	3	PF00520
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	HSPD1 MYH1 MYH8 MYH11 MYO1A ZNF608 KDM5A DSP DNAJA4 AHNAK SCN4A SUPT16H CBX3 KIF5A GPR101 CAMSAP2 PGAM2 TASOR HMGN4 PGK1 TOP2A PCID2	1.50e-14	1442	67	22	35575683
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	HSPD1 DDX46 MAP7D3 DSP CCDC174 AHNAK SUPT16H CBX3 SYT1 THOC2 PCBP2 TASOR HMGN4 TOP2A	3.15e-09	954	67	14	36373674
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	HSPD1 MYH1 MYH8 MYH11 TBC1D9B MYO1A DSP AHNAK PCBP2 PGAM2 PGK1 TOP2A	3.66e-09	647	67	12	26618866
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	OTOF DSP AHNAK SUPT16H THOC2 ARHGEF17 SLC4A5 TOP2A	1.73e-08	234	67	8	36243803
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	HSPD1 DDX46 MAP7D3 KDM5A DSP GLYR1 AHNAK SUPT16H CBX3 THOC2 PCBP2 TASOR HMGN4 AHDC1 TOP2A	1.88e-08	1294	67	15	30804502
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	HSPD1 DDX46 MAP7D3 DSP AHNAK CBX3 THOC2 PCBP2 CAMSAP2 TASOR PGK1 TOP2A	2.03e-07	934	67	12	33916271
Pubmed	LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.	HSPD1 MYH11 AHNAK SUPT16H PCBP2 PGAM2 PGK1 TOP2A	2.26e-07	327	67	8	31409639
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	HSPD1 MYH11 DDX46 MAP7D3 DSP GLYR1 AHNAK SUPT16H THOC2 KLHDC4 PCBP2 TOP2A	2.40e-07	949	67	12	36574265
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	ARHGEF10 GLYR1 AHNAK SUPT16H ZC3H11B SLC4A5 AHDC1 TOP2A	2.53e-07	332	67	8	37433992
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	HSPD1 DSP AHNAK SUPT16H CBX3 THOC2 PCBP2 HMGN4 PGK1 TOP2A	4.75e-07	652	67	10	31180492
Pubmed	Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting.	HSPD1 MYH1 MYH8 DSP AHNAK PGAM2	5.67e-07	155	67	6	22673621
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	HSPD1 DDX46 RNF213 ARMCX2 THOC2 PGK1 TOP2A	7.52e-07	262	67	7	36880596
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	HSPD1 DDX46 KDM5A DSP GLYR1 DHRS7 SUPT16H CBX3 CHD9 THOC2 PCBP2 AHDC1	9.59e-07	1082	67	12	38697112
Pubmed	The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.	HSPD1 DDX46 DSP AHNAK PCBP2 PGK1 TOP2A	3.47e-06	330	67	7	32529326
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	DDX46 TCEAL4 AHNAK SUPT16H CBX3 RNF213 CHD9 THOC2 HMGN4 PGK1 TOP2A	3.54e-06	1014	67	11	32416067
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	GLYR1 SUPT16H CBX3 RNF213 TASOR TOP2A PCID2	3.61e-06	332	67	7	25693804
Pubmed	Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis.	OTOF SYT1	3.66e-06	2	67	2	21451027
Pubmed	Topoisomerase II alpha and microtubule-associated protein-tau as a predictive marker in axillary lymph node positive breast cancer.	MAPT TOP2A	3.66e-06	2	67	2	24675496
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	HSPD1 DDX46 DSP AHNAK SUPT16H CBX3 THOC2 PCBP2 PGK1 TOP2A SNX2	3.89e-06	1024	67	11	24711643
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	HSPD1 MYH1 MYH8 DSP AHNAK CBX3 RNF213 PCBP2 PGK1 TOP2A	4.77e-06	844	67	10	25963833
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAP7D3 ARHGEF10 KDM5A DSP MAPT AHNAK FSD1 ARHGEF17 CAMSAP2 SNX2	5.69e-06	861	67	10	36931259
Pubmed	Synapsin and synaptic vesicle protein expression during embryonic and post-natal lens fiber cell differentiation.	MAPT SYT1 KIF5A	6.48e-06	19	67	3	15529118
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	MYH8 XIRP2 DNAH17	7.61e-06	20	67	3	21689717
Pubmed	Study of FOXO1-interacting proteins using TurboID-based proximity labeling technology.	DDX46 XIRP2 DSP MAPT AHNAK PCBP2	7.64e-06	243	67	6	36964488
Pubmed	CCAT1/FABP5 promotes tumour progression through mediating fatty acid metabolism and stabilizing PI3K/AKT/mTOR signalling in lung adenocarcinoma.	HSPD1 MYH11 DSP PGK1	7.79e-06	65	67	4	34431227
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	SUPT16H SNX18 CBX3 CHD9 THOC2 HMGN4 TOP2A PCID2	8.52e-06	533	67	8	30554943
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	DDX46 MAP7D3 DSP AHNAK THOC2 PCBP2 TOP2A SNX2	1.06e-05	549	67	8	38280479
Pubmed	Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor.	CARS1 RNF213	1.10e-05	3	67	2	12112524
Pubmed	Otoferlin is a multivalent calcium-sensitive scaffold linking SNAREs and calcium channels.	OTOF SYT1	1.10e-05	3	67	2	28696301
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	GLYR1 AHNAK SUPT16H SNX18 CBX3 CHD9 TOP2A	1.10e-05	394	67	7	27248496
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	HSPD1 MYH11 DDX46 KDM5A DSP GLYR1 SUPT16H CHD9 KIF5A PCBP2 PGK1	1.19e-05	1153	67	11	29845934
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	HSPD1 ZNF608 KDM5A DSP CBX3 PCBP2	1.45e-05	272	67	6	31010829
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	HSPD1 DDX46 DSP DNAJA4 AHNAK SUPT16H CARS1 CBX3 PCBP2 PGAM2 PGK1 TOP2A	1.48e-05	1415	67	12	28515276
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	HSPD1 DSP GLYR1 AHNAK SUPT16H CBX3 CLSPN THOC2 PCBP2 TOP2A	1.89e-05	989	67	10	36424410
Pubmed	CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.	HSPD1 MYH11 MYO1A DSP PCBP2 PGK1	2.00e-05	288	67	6	31501420
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	HSPD1 DDX46 DSP GLYR1 SUPT16H CBX3 PCBP2 TOP2A	2.12e-05	605	67	8	28977666
Pubmed	Evaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.	MYH1 MYH8	2.19e-05	4	67	2	20357587
Pubmed	An SRp75/hnRNPG complex interacting with hnRNPE2 regulates the 5' splice site of tau exon 10, whose misregulation causes frontotemporal dementia.	MAPT PCBP2	2.19e-05	4	67	2	21723381
Pubmed	Three linked myosin heavy chain genes clustered within 370 kb of each other show independent transcriptional and post-transcriptional regulation during differentiation of a mouse muscle cell line.	MYH1 MYH8	2.19e-05	4	67	2	1985022
Pubmed	Control of exocytosis by synaptotagmins and otoferlin in auditory hair cells.	OTOF SYT1	2.19e-05	4	67	2	20926654
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	HSPD1 ZNF608 CBX3 CHD9 THOC2 PCBP2 CAMSAP2 AHDC1 PGK1 TOP2A PCID2	2.45e-05	1247	67	11	27684187
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	HSPD1 MAP7D3 DSP GLYR1 AHNAK MKRN2 SUPT16H CBX3 THOC2 PGK1 TOP2A	2.64e-05	1257	67	11	36526897
Pubmed	Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event.	HSPD1 DSP GLYR1 SUPT16H CBX3	2.76e-05	182	67	5	26527279
Pubmed	Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.	MYH11 DSP AHNAK PGK1	3.09e-05	92	67	4	37343697
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	HSPD1 MAP7D3 DSP TCEAL4 CLSPN ARHGEF17 PCBP2 PCID2	3.12e-05	639	67	8	23443559
Pubmed	Large-scale analysis of the human ubiquitin-related proteome.	HSPD1 MYH1 DNAJA4 RNF213 PCBP2 PCID2	3.19e-05	313	67	6	16196087
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	MAP7D3 ZNF608 GLYR1 AHNAK SUPT16H KIF5A THOC2 HMGN4	3.34e-05	645	67	8	25281560
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	HSPD1 MYH11 DSP CARS1 KIF5A THOC2 PGAM2 HMGN4 PGK1	3.49e-05	847	67	9	35235311
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	HSPD1 MAP7D3 DSP DNAJA4 AHNAK CARS1 CBX3 PLCB4 ARHGEF17 PCBP2 PCID2	3.51e-05	1297	67	11	33545068
Pubmed	Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.	MYH1 MYH8	3.64e-05	5	67	2	6196357
Pubmed	Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport.	MAPT KIF5A	3.64e-05	5	67	2	27629715
Pubmed	Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.	MYH1 MYH8	3.64e-05	5	67	2	3829126
Pubmed	Myosin heavy chain isoforms of the murine masseter muscle during pre- and post-natal development.	MYH1 MYH8	3.64e-05	5	67	2	12919077
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	HSPD1 MAP7D3 DSP SNX18 PCBP2 CAMSAP2 TOP2A SNX2 PCID2	3.69e-05	853	67	9	28718761
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	DDX46 AHNAK SUPT16H CBX3 THOC2 PCBP2 TOP2A PCID2	3.93e-05	660	67	8	32780723
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	HSPD1 DDX46 KDM5A AHNAK SUPT16H CBX3 THOC2 PCBP2 TOP2A SNX2 PCID2	4.06e-05	1318	67	11	30463901
Pubmed	Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.	HSPD1 MYH1 MYH8 MYH11 DDX46 DSP	4.35e-05	331	67	6	29199018
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	DSP DNAJA4 AHNAK MKRN2 SUPT16H CHD9 PGK1	4.66e-05	494	67	7	26831064
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	MYH11 DDX46 DSP AHNAK THOC2 TOP2A	5.05e-05	340	67	6	24332808
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF608 KDM5A MAPT SUPT16H CBX3 RNF213 CHD9 CLSPN TOP2A PCID2	5.24e-05	1116	67	10	31753913
Pubmed	Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.	AHNAK SUPT16H CARS1 TOP2A	5.39e-05	106	67	4	19394292
Pubmed	Glycolytic enzymes can modulate cellular life span.	PGAM2 PGK1	5.46e-05	6	67	2	15665293
Pubmed	Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.	MYH1 MYH8	5.46e-05	6	67	2	1728586
Pubmed	Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.	MYH1 MYH8	5.46e-05	6	67	2	10077619
Pubmed	Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.	MYH1 MYH8	5.46e-05	6	67	2	10588881
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	DDX46 DSP TCEAL4 AHNAK DHRS7 SUPT16H CBX3 RNF213 PCBP2 PGK1 TOP2A	5.65e-05	1367	67	11	32687490
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	MYH11 DDX46 KDM5A DSP GLYR1 AHNAK SUPT16H CBX3 THOC2 PCBP2 PGK1	5.80e-05	1371	67	11	36244648
Pubmed	The tumour suppressor PTEN mediates a negative regulation of the E3 ubiquitin-protein ligase Nedd4.	HSPD1 AHNAK PCBP2 PGK1	6.23e-05	110	67	4	18307411
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	HSPD1 DDX46 DSP CBX3 CLSPN PCBP2	6.61e-05	357	67	6	37059091
Pubmed	TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.	SYT1 TOP2A	7.63e-05	7	67	2	24658003
Pubmed	A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.	MYH1 MYH8	7.63e-05	7	67	2	35210422
Pubmed	Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.	MYH1 MYH8	7.63e-05	7	67	2	16819597
Pubmed	Topoisomerase II regulates the maintenance of DNA methylation.	SUPT16H TOP2A	7.63e-05	7	67	2	25451918
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	HSPD1 DDX46 DSP SUPT16H THOC2 PCBP2 TOP2A PCID2	8.02e-05	731	67	8	29298432
Pubmed	The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.	HSPD1 MYH11 PDE6C MAPT SYT1 PCBP2 PGK1	9.33e-05	552	67	7	36293380
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	KDM5A DNAJA4 SUPT16H CBX3 SYT1 KIF5A ARHGEF26 CAMSAP2 PGK1	9.35e-05	963	67	9	28671696
Pubmed	Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.	KDM5A GLYR1 CBX3 AHDC1	9.92e-05	124	67	4	20850016
Pubmed	Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.	HSPD1 MAPT AHNAK CBX3 SYT1 FSD1 SNCG	9.97e-05	558	67	7	35063084
Pubmed	Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.	MYH1 MYH8	1.02e-04	8	67	2	3864153
Pubmed	A yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIH.	HSPD1 KDM5A	1.02e-04	8	67	2	11445587
Pubmed	Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II.	CBX3 TOP2A	1.02e-04	8	67	2	22308494
Pubmed	Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner.	OTOF PGK1	1.02e-04	8	67	2	28209736
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	DDX46 MAP7D3 GLYR1 SUPT16H THOC2 TASOR TOP2A PCID2	1.04e-04	759	67	8	35915203
Pubmed	An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.	HSPD1 DSP AHNAK SUPT16H PCBP2 PGK1	1.18e-04	397	67	6	21319273
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	DDX46 KDM5A DSP MAPT THOC2 KLHDC4 TOP2A SNX2	1.19e-04	774	67	8	15302935
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	MKRN2 SUPT16H HMGN4 PGK1 TOP2A SNX2	1.23e-04	400	67	6	35013556
Pubmed	Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.	MYH1 MYH8 RYR3	1.26e-04	50	67	3	27597886
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	AHNAK SUPT16H CBX3 TOP2A PCID2	1.26e-04	251	67	5	31076518
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	HSPD1 DDX46 DSP AHNAK PCBP2 TOP2A SNX2	1.29e-04	582	67	7	20467437
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	HSPD1 MAP7D3 GLYR1 PCBP2 HMGN4 TOP2A	1.43e-04	411	67	6	35182466
Pubmed	Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers.	HSPD1 DDX46 GLYR1 AHNAK CBX3	1.46e-04	259	67	5	31162944
Pubmed	Accelerating functional gene discovery in osteoarthritis.	DNAH17 MKRN2 ARHGAP30	1.49e-04	53	67	3	33473114
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	HSPD1 DSP AHNAK PCBP2 PGAM2 HMGN4 PGK1 TOP2A	1.53e-04	803	67	8	36517590
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF608 KDM5A DSP AHNAK CBX3 TASOR	1.56e-04	418	67	6	34709266
Pubmed	The role of hereditary spastic paraplegia related genes in multiple sclerosis. A study of disease susceptibility and clinical outcome.	HSPD1 KIF5A	1.63e-04	10	67	2	17420921
Pubmed	During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation.	MYH1 MYH8	1.63e-04	10	67	2	19506036
Pubmed	Acceleration of somitic myogenesis in embryos of myogenin promoter-MRF4 transgenic mice.	MYH1 MYH8	1.63e-04	10	67	2	8950513
Pubmed	LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.	HSPD1 DDX46 PCBP2 PGK1	1.67e-04	142	67	4	30809309
Pubmed	Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation.	HSPD1 AHNAK CBX3 PCBP2 TOP2A	1.80e-04	271	67	5	26816005
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	DDX46 GLYR1 AHNAK THOC2 TOP2A	1.80e-04	271	67	5	32433965
Interaction	SMC5 interactions	HSPD1 MYH1 DDX46 MAP7D3 DSP CCDC174 AHNAK SUPT16H CBX3 SYT1 THOC2 PCBP2 TASOR HMGN4 TOP2A	6.09e-07	1000	66	15	int:SMC5
Interaction	NAA40 interactions	HSPD1 DDX46 MAP7D3 DSP AHNAK SUPT16H CBX3 THOC2 PCBP2 CAMSAP2 TASOR PGK1 TOP2A	1.43e-05	978	66	13	int:NAA40
Interaction	AURKB interactions	HSPD1 MYH11 DDX46 MYO1A DSP TCEAL4 AHNAK CBX3 RNF213 TOP2A SNX2	3.34e-05	761	66	11	int:AURKB
Interaction	NUP43 interactions	HSPD1 ZNF608 KDM5A DSP GLYR1 SUPT16H CHD9 CCDC168 AHDC1 TOP2A	3.38e-05	625	66	10	int:NUP43
Interaction	MEX3A interactions	ARHGEF10 GLYR1 AHNAK SUPT16H ZC3H11B SLC4A5 AHDC1 TOP2A	3.54e-05	384	66	8	int:MEX3A
Interaction	BRCA1 interactions	HSPD1 DSP MAPT DNAJA4 AHNAK MKRN2 SUPT16H CARS1 CBX3 CHD9 CLSPN PCBP2 PGK1 TOP2A	4.25e-05	1249	66	14	int:BRCA1
Interaction	CBX3 interactions	HSPD1 MAPT GLYR1 SUPT16H CBX3 CHD9 CLSPN AHDC1 PGK1 TOP2A	4.46e-05	646	66	10	int:CBX3
Interaction	YAP1 interactions	HSPD1 MYH11 DDX46 MAP7D3 MYO1A DSP AHNAK SUPT16H KIF5A THOC2 PCBP2 PGK1 SNX2	4.65e-05	1095	66	13	int:YAP1
Interaction	KDM1A interactions	ZNF608 KDM5A DSP MAPT GLYR1 AHNAK MKRN2 SUPT16H CBX3 THOC2 KLHDC4 TASOR	4.79e-05	941	66	12	int:KDM1A
Interaction	EED interactions	HSPD1 MYH11 TBC1D9B XIRP2 KDM5A DSP GLYR1 SUPT16H SNX18 CBX3 THOC2 PCBP2 PGK1 TOP2A SNX2	5.21e-05	1445	66	15	int:EED
Interaction	LOXL2 interactions	HSPD1 MYH11 AHNAK SUPT16H PCBP2 PGAM2 PGK1 TOP2A	5.61e-05	410	66	8	int:LOXL2
Interaction	FMR1 interactions	KDM5A MAPT AHNAK MKRN2 SUPT16H CBX3 KIF5A CAMSAP2 TOP2A	5.98e-05	536	66	9	int:FMR1
Interaction	CCAT1 interactions	HSPD1 MYH11 DSP PGK1	6.11e-05	65	66	4	int:CCAT1
Interaction	RYR3 interactions	HSPD1 DSP RYR3	6.46e-05	24	66	3	int:RYR3
Interaction	USP7 interactions	OTOF DSP MAPT TCEAL4 AHNAK SUPT16H ARHGAP30 SNCG ARMCX2 CLSPN THOC2 ARHGEF17 SLC4A5 TOP2A	7.30e-05	1313	66	14	int:USP7
Interaction	CHMP4C interactions	MYH11 DSP MAPT AHNAK SUPT16H CBX3 RNF213 PCBP2 PGK1 TOP2A	7.47e-05	687	66	10	int:CHMP4C
Interaction	OXCT1 interactions	HSPD1 MAPT AHNAK CBX3 PGK1	7.51e-05	133	66	5	int:OXCT1
Interaction	METTL14 interactions	HSPD1 DDX46 DSP AHNAK CBX3 KIF5A PCBP2 TOP2A RYR3	8.14e-05	558	66	9	int:METTL14
Interaction	H3C6 interactions	HSPD1 DSP GLYR1 SUPT16H CBX3 TOP2A	9.65e-05	226	66	6	int:H3C6
Interaction	H2BC9 interactions	OTOF XIRP2 DSP AHNAK SUPT16H KIF5A HMGN4 TOP2A	1.01e-04	446	66	8	int:H2BC9
Interaction	DDB2 interactions	HSPD1 DSP SUPT16H CLSPN TOP2A	1.06e-04	143	66	5	int:DDB2
Interaction	NDN interactions	HSPD1 DDX46 DSP AHNAK MKRN2 PCBP2 PGK1 TOP2A	1.12e-04	453	66	8	int:NDN
Interaction	MEN1 interactions	DDX46 ZNF608 GLYR1 SUPT16H CBX3 RNF213 THOC2 ARHGEF17 TASOR AHDC1 TOP2A PCID2	1.13e-04	1029	66	12	int:MEN1
Interaction	KIF23 interactions	HSPD1 MYH11 MYO1A DSP AHNAK SUPT16H CBX3 CHD9 THOC2 HHLA1 PCBP2 TOP2A	1.15e-04	1031	66	12	int:KIF23
Interaction	RAPGEFL1 interactions	ARHGEF10 ARHGAP30 ARHGEF17	1.15e-04	29	66	3	int:RAPGEFL1
Interaction	CHMP4B interactions	HSPD1 MYH11 DDX46 DSP MAPT AHNAK SUPT16H ARHGEF17 PCBP2 TOP2A	1.19e-04	727	66	10	int:CHMP4B
Interaction	RTN4 interactions	HSPD1 DDX46 MAPT DHRS7 MKRN2 SNX2 RYR3	1.23e-04	341	66	7	int:RTN4
Interaction	TRIM63 interactions	HSPD1 MYH1 MYH8 TCEAL4 CARS1 KIF5A KLHDC4	1.30e-04	344	66	7	int:TRIM63
Interaction	OBSL1 interactions	HSPD1 SLC9C1 DDX46 DSP GLYR1 AHNAK SUPT16H CBX3 THOC2 PCBP2 TOP2A	1.53e-04	902	66	11	int:OBSL1
Interaction	ARL16 interactions	HSPD1 GLYR1 CLSPN TASOR	1.59e-04	83	66	4	int:ARL16
Interaction	VPS26B interactions	MYH1 CHD9 KIF5A SNX2	1.82e-04	86	66	4	int:VPS26B
Interaction	PML interactions	HSPD1 DDX46 ZNF608 AHNAK RNF213 ARMCX2 THOC2 AHDC1 PGK1 TOP2A PCID2	2.05e-04	933	66	11	int:PML
Interaction	CIT interactions	HSPD1 MYH11 DDX46 DSP GLYR1 AHNAK SUPT16H CBX3 RNF213 THOC2 PCBP2 TOP2A SNX2 PCID2	2.09e-04	1450	66	14	int:CIT
Interaction	OVCA2 interactions	MYH11 DSP	2.19e-04	7	66	2	int:OVCA2
Interaction	SUZ12 interactions	HSPD1 KDM5A GLYR1 SUPT16H CBX3 THOC2 TASOR AHDC1 PGK1	2.39e-04	644	66	9	int:SUZ12
Interaction	MAPT interactions	HSPD1 MAPT AHNAK CARS1 CBX3 SYT1 FSD1 KIF5A SNCG PCBP2 PGK1 TIGD6	2.46e-04	1119	66	12	int:MAPT
Interaction	CFTR interactions	HSPD1 MYH1 MYH8 MYH11 TBC1D9B MYO1A DSP AHNAK SUPT16H PCBP2 PGAM2 PGK1 TOP2A RYR3	2.58e-04	1480	66	14	int:CFTR
Interaction	FBXO32 interactions	HSPD1 MYH1 MYH8 DSP AHNAK PGAM2 TOP2A	2.64e-04	386	66	7	int:FBXO32
Interaction	AAR2 interactions	HSPD1 DDX46 DSP AHNAK CARS1 CBX3 PCBP2 PGAM2 PGK1	2.77e-04	657	66	9	int:AAR2
Interaction	PRC1 interactions	HSPD1 DDX46 DSP GLYR1 AHNAK SUPT16H CBX3 ARHGEF17 PCBP2 HMGN4 TOP2A	2.94e-04	973	66	11	int:PRC1
Interaction	RIMS1 interactions	MYH1 MAPT SYT1	3.04e-04	40	66	3	int:RIMS1
Interaction	HECTD1 interactions	HSPD1 DDX46 MAP7D3 ARHGEF10 TCEAL4 GLYR1 SUPT16H THOC2 TASOR TOP2A PCID2	3.24e-04	984	66	11	int:HECTD1
Interaction	ATG16L1 interactions	HSPD1 MAPT SUPT16H SNX18 CARS1 CBX3 SYT1 ARHGAP30 CCDC168 ARHGEF17 TOP2A PCID2	3.45e-04	1161	66	12	int:ATG16L1
Interaction	H2BC11 interactions	MAPT SUPT16H CBX3 HMGN4 TOP2A	3.60e-04	186	66	5	int:H2BC11
Interaction	AURKC interactions	MYH1 MYH8 MYH11	3.77e-04	43	66	3	int:AURKC
Interaction	RYR1 interactions	MYH1 XIRP2 DSP	3.77e-04	43	66	3	int:RYR1
Interaction	VDAC1 interactions	HSPD1 MYH11 MAPT AHNAK SUPT16H CBX3 PGAM2 TOP2A	3.79e-04	542	66	8	int:VDAC1
Interaction	STIP1 interactions	HSPD1 DDX46 ARHGEF10 MAPT AHNAK MKRN2 SUPT16H THOC2 PCBP2 PGK1 SNX2	3.91e-04	1006	66	11	int:STIP1
Interaction	CUL7 interactions	HSPD1 DDX46 DSP AHNAK SUPT16H CBX3 THOC2 PCBP2 PGK1 TOP2A	3.99e-04	845	66	10	int:CUL7
Interaction	NET1 interactions	ARHGEF10 ARHGAP30 ARHGEF17	4.04e-04	44	66	3	int:NET1
Interaction	SPICE1 interactions	MAP7D3 MAPT SUPT16H CAMSAP2 TOP2A	4.06e-04	191	66	5	int:SPICE1
Interaction	H2BC21 interactions	HSPD1 OTOF GLYR1 AHNAK SUPT16H CBX3 ARHGAP30 HMGN4 TOP2A	4.23e-04	696	66	9	int:H2BC21
Interaction	TERF2IP interactions	ZNF608 CBX3 SNCG CLSPN THOC2 TASOR HMGN4 TOP2A	4.28e-04	552	66	8	int:TERF2IP
Interaction	TRIB2 interactions	HSPD1 PCBP2 TOP2A	4.91e-04	47	66	3	int:TRIB2
Interaction	IFI16 interactions	HSPD1 GLYR1 SUPT16H CBX3 RNF213 PCBP2 TASOR TOP2A PCID2	5.08e-04	714	66	9	int:IFI16
Interaction	TNIP1 interactions	HSPD1 MYH11 DDX46 MAP7D3 DSP GLYR1 AHNAK SUPT16H THOC2 KLHDC4 PCBP2 TOP2A	5.27e-04	1217	66	12	int:TNIP1
Interaction	SLX4 interactions	HSPD1 DDX46 DSP SUPT16H CBX3 CHD9 CLSPN PCBP2	5.42e-04	572	66	8	int:SLX4
Interaction	ECT2 interactions	HSPD1 MYH11 DDX46 MYO1A DSP AHNAK SUPT16H ARHGEF17 PCBP2 TOP2A	5.84e-04	887	66	10	int:ECT2
Interaction	H3C15 interactions	XIRP2 KDM5A DSP SUPT16H CBX3	5.86e-04	207	66	5	int:H3C15
GeneFamily	Myosin heavy chains	MYH1 MYH8 MYH11	9.96e-06	15	52	3	1098
GeneFamily	Sorting nexins\|PX-BAR domain containing	SNX18 SNX2	5.26e-04	12	52	2	1290
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF10 ARHGEF26 ARHGEF17	9.04e-04	66	52	3	722
GeneFamily	Sorting nexins\|PX-BAR domain containing	SNX18 SNX2	3.13e-03	29	52	2	754
Coexpression	PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN	MYH11 KDM5A SNX18 SNCG THOC2	7.56e-06	107	66	5	MM947
Coexpression	PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN	MYH11 KDM5A SNX18 SNCG THOC2	8.28e-06	109	66	5	M2451
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	DDX46 KDM5A TCEAL4 AHNAK CLSPN THOC2 TOP2A	1.93e-08	197	67	7	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OTOF MAPT SYT1 KIF5A SNCG PGAM2	2.98e-07	179	67	6	228d12ed1c8dc92aefbcea4aaf7d108783c22be0
ToppCell	droplet-Limb_Muscle-Pre-Sort\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 AHNAK CBX3 SNCG PCBP2 PGAM2	3.07e-07	180	67	6	af2bafcd1b2082629de3ea336711add01565c4c4
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 AHNAK CBX3 SNCG PCBP2 PGAM2	3.07e-07	180	67	6	f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANO2 MAPT SYT1 KIF5A SNCG PGAM2	3.50e-07	184	67	6	abb61e744a9031e0c91eb560a8f486a0ca5a01cc
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 FSD1 KIF5A SNCG PGAM2	5.37e-07	198	67	6	7b9c7ce5d6b7df8db85943b65da1a2c202a8bb53
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 FSD1 KIF5A SNCG PGAM2	5.54e-07	199	67	6	646d6e84a2e70042ee5d68a045abb3fc6741fcc7
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP2 AHNAK SUPT16H CHD9 TASOR	6.87e-06	176	67	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 KIF5A SNCG PGAM2	7.45e-06	179	67	5	d96741c5c551e36421b2ad938072ab7d506c3835
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OTOF MAPT SYT1 KIF5A SNCG	7.45e-06	179	67	5	b8ca29aebd25ebac441bebd769bbf98c536d3166
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 KIF5A SNCG PGAM2	7.66e-06	180	67	5	7d3d5608647b6e684e8e185993d106a38c53e76a
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 FSD1 KIF5A SNCG	7.66e-06	180	67	5	368ff7fcfd21ad248f96a83a8b191040ba7d8670
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 ANO2 XIRP2 KIF5A RYR3	8.52e-06	184	67	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 ANO2 XIRP2 KIF5A RYR3	8.52e-06	184	67	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 ANO2 XIRP2 KIF5A RYR3	8.52e-06	184	67	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM132C MYH11 SYT1 PLCB4 ARHGEF17	8.75e-06	185	67	5	51dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM132C MYH11 SYT1 PLCB4 ARHGEF17	8.75e-06	185	67	5	a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 KIF5A SNCG PGAM2	8.75e-06	185	67	5	94d0f283d63d932f310cc5a17ea893d71ba60f5e
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 FSD1 KIF5A PGAM2	9.21e-06	187	67	5	a748b3a59e398e0da019db3f16d38adb1960c29f
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ANO2 ZNF608 CHD9 PCBP2 SNX2	9.95e-06	190	67	5	f623f0bdece6002b68ac2207e99408b24a2b1194
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ITGA11 MYH11 PLCB4 SNCG ARHGEF17	1.05e-05	192	67	5	fee99ca7e658963acf968aa724ef8c96cfc00a5d
ToppCell	Fibroblast-D_(Pericyte)\|World / shred on cell class and cell subclass (v4)	ITGA11 MYH11 MAPT ARMCX2 ARHGEF17	1.05e-05	192	67	5	8c13c351fcc3d88e8c2ffa017e71ff6272cc6fac
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGEF10 AHNAK CHD9 THOC2 SNX2	1.07e-05	193	67	5	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 FSD1 KIF5A PGAM2	1.10e-05	194	67	5	15224fb3e7ca5bd1fb8c41f8275842f737014095
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma\|TCGA-Adrenal / Sample_Type by Project: Shred V9	MAPT SYT1 PLCB4 KIF5A ARHGEF17	1.10e-05	194	67	5	b6488bc3a8905e926ad298332963e1bbaf010046
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma\|TCGA-Adrenal / Sample_Type by Project: Shred V9	MAPT SYT1 PLCB4 KIF5A ARHGEF17	1.10e-05	194	67	5	1e1f4139ad584f493d75a9b7f1568eca4653c5a2
ToppCell	18-Airway-Epithelial-Epithelial\|Airway / Age, Tissue, Lineage and Cell class	MAPT SYT1 FSD1 KIF5A SNCG	1.10e-05	194	67	5	d3c90e1f1228f8ba0ba56105c6cf4f302c388f28
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 KIF5A SNCG PGAM2	1.19e-05	197	67	5	b9478212f14b7888e3abac02995177974ac3bd17
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 KIF5A SNCG PGAM2	1.19e-05	197	67	5	27c044833e471a312a572e0b1c83e4bc8a36e896
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 KIF5A SNCG PGAM2	1.19e-05	197	67	5	fd43fc1cbf0c17b370397d73dddc572565a759c7
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 KIF5A SNCG PGAM2	1.19e-05	197	67	5	a07e1a9b95c9f8a09452cbfe5a9f06648f66e29e
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 FSD1 KIF5A PGAM2	1.19e-05	197	67	5	c220102fadbb7ba385a61704a144e0b814cb5c46
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 KIF5A SNCG PGAM2	1.21e-05	198	67	5	85881637641d8996be2edc65c4bceff0433135e7
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 FSD1 SNCG PGAM2	1.21e-05	198	67	5	328f1d5d8168e05edd301d3a0f2eb5c6cd1c67c8
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 KIF5A SNCG PGAM2	1.21e-05	198	67	5	800ade4261695f2efd869d2b1243571de963c431
ToppCell	COVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil\|COVID-19_Mild / Disease, condition lineage and cell class	ITGA11 CCDC168 CLSPN CAMSAP2 TOP2A	1.24e-05	199	67	5	e222b90caf45904d8f763574e7b6aac13333df92
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 KIF5A SNCG PGAM2	1.24e-05	199	67	5	ce8dbfd969b3b9c08e1c57c2bfd899818e878731
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 FSD1 SNCG PGAM2	1.27e-05	200	67	5	51d20543a9c9330c34c085d9290a1fc8b5bff0d4
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TMEM132C MYH1 MYH8 HHLA1	1.40e-05	97	67	4	f3c3fb260954f594a9ab8e1ac9a01115767cbc7a
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TMEM132C MYH1 MYH8 CACNA2D3	7.14e-05	147	67	4	50e86860a94be103092c40e39a172eac92372f0d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TMEM132C MYH1 MYH8 GPR101	9.22e-05	157	67	4	741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	XIRP2 AHNAK ARHGAP30 CCDC168	9.68e-05	159	67	4	bf8ff9251bcb64b2b9d6dd93461aec97659686ec
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH8 MYH11 RYR3 CACNA2D3	9.92e-05	160	67	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 SCN4A SYT1 GPR101	9.92e-05	160	67	4	f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D231\|Adult / Lineage, Cell type, age group and donor	MYH11 PLCB4 KIF5A RYR3	9.92e-05	160	67	4	d783d29150033e9181c0e30870070268fed3fd85
ToppCell	facs-Marrow-T-cells-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP7D3 SCN4A PGAM2 AHDC1	9.92e-05	160	67	4	b3f7ef7e682b48a83ca425f5c439336e96168300
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH8 MYH11 RYR3 CACNA2D3	9.92e-05	160	67	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM132C SLC9C1 KIF5A CACNA2D3	1.02e-04	161	67	4	4bb7bae54ba3bdf46b525c01f5ad3db8e49819cb
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	XIRP2 ZC3H11B PLCB4 RYR3	1.09e-04	164	67	4	d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MYH1 MYH8 GPR101	1.12e-04	62	67	3	a20620a8869721ea62984c2022ee1b484b455824
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MYH1 MYH8 GPR101	1.12e-04	62	67	3	ee694c06bcd924b4ddf744178ba3a99e04eed51b
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN4A CLSPN PGAM2 TOP2A	1.14e-04	166	67	4	bb8135119dc37fdbba476599a56d368f422688dc
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH8 MYH11 OTOF PGAM2	1.14e-04	166	67	4	390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH8 MYH11 OTOF PGAM2	1.14e-04	166	67	4	9a341dc7b756252caeaac1e934384911c880a634
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	KIF5A CLSPN TOP2A RYR3	1.17e-04	167	67	4	315cde87eed2b42a1b9b068fae94caa10ec64c70
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYH1 MYH8 XIRP2 PGAM2	1.17e-04	167	67	4	d78356bf0c473816dbabaee51984940bd822f84e
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH8 MYH11 OTOF PGAM2	1.17e-04	167	67	4	91b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	ANO2 PLCB4 SNCG RYR3	1.20e-04	168	67	4	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 SNCG PGAM2 CACNA2D3	1.22e-04	169	67	4	88aa2246ede582c2e11de63228d76f520889ecb3
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 SNCG PGAM2 CACNA2D3	1.22e-04	169	67	4	a6a5b00912b653fad2ca7f096deaf35c9ef85e5b
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 SNCG PGAM2 CACNA2D3	1.22e-04	169	67	4	42a9b8c77d2a4d68b01e4db38f8a1af53c9c814f
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 OTOF PLCB4 PGAM2	1.25e-04	170	67	4	cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DSP SYT1 CCDC168 KIF5A	1.25e-04	170	67	4	98d13dbd76a826e47d55553f9d11f71c043b573e
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 OTOF PLCB4 PGAM2	1.25e-04	170	67	4	da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM132C ITGA11 MYH11 ARHGEF17	1.25e-04	170	67	4	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM132C ITGA11 MYH11 ARHGEF17	1.25e-04	170	67	4	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM132C ITGA11 MYH11 ARHGEF17	1.25e-04	170	67	4	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	facs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF10 AHNAK SNX18 KIF5A	1.28e-04	171	67	4	6a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP7D3 ARHGAP30 KLHDC4 TOP2A	1.28e-04	171	67	4	845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KIF5A CLSPN TOP2A RYR3	1.28e-04	171	67	4	4ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 OTOF SYT1 RYR3	1.28e-04	171	67	4	82de2885c8ce4fb7776da6a0207b3355c0910121
ToppCell	facs-Marrow-T-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF10 AHNAK SNX18 KIF5A	1.28e-04	171	67	4	e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 OTOF SYT1 RYR3	1.28e-04	171	67	4	09e653973962fb884878089d281f0947f7a285f6
ToppCell	T_cells-CD56_bright_CD16-_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	TMEM132C FSD1 PLCB4 RYR3	1.31e-04	172	67	4	980e8b9e1ceeb0dec9eb9ef95c139e5ffe99b6e4
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYH11 SNCG ARHGEF17 PGAM2	1.43e-04	176	67	4	90f36f10c6ed440a0ca549f23219398853f1fbc3
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OTOF MAPT SYT1 FSD1	1.43e-04	176	67	4	bfea433544c6d6b8ad55e50ca94c5574460c2e0b
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 KIF5A SNCG	1.43e-04	176	67	4	04dad262929581872e5bbc66cd8182c963e7e52f
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OTOF MAPT SYT1 FSD1	1.43e-04	176	67	4	3c78dee7e1111a579fde6d401b9ecb4d5b8e782f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 MYH11 PLCB4 ARHGEF17	1.46e-04	177	67	4	4943d040eee0f9dceaddc7498171281d170e271f
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH8 MYH11 OTOF PGAM2	1.46e-04	177	67	4	c9b02a2e1ff2aa18c37e88a53b06a5b696a442ae
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 MYH11 PLCB4 ARHGEF17	1.46e-04	177	67	4	3f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 MYH11 PLCB4 ARHGEF17	1.46e-04	177	67	4	a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 MYH11 PLCB4 ARHGEF17	1.46e-04	177	67	4	3645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Myofibroblast\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO2 ITGA11 AHNAK SCN4A	1.49e-04	178	67	4	1802ff1c6cb18ee62cfef7270c0971048fae5315
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Myofibroblast-VLMC_L1-3_CYP1B1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO2 ITGA11 AHNAK SCN4A	1.49e-04	178	67	4	4368d20130e5a08716564c19470b6014f16902ac
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 MKRN2 ARMCX2 PCID2	1.53e-04	179	67	4	b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMEM132C SLC9C1 MYH11 SYT1	1.53e-04	179	67	4	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	MYH11 XIRP2 PLCB4 CACNA2D3	1.53e-04	179	67	4	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 MAPT ARMCX2 ARHGEF17	1.53e-04	179	67	4	56db12467b445f2b8ef92af50779eeab10413eb2
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF10 AHNAK KIF5A PGAM2	1.56e-04	180	67	4	df60970520fba2ac0639faa54096766d07418ca4
ToppCell	facs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF10 AHNAK SNX18 PGAM2	1.59e-04	181	67	4	782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCell	facs-Marrow-B-cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF10 AHNAK SNX18 PGAM2	1.59e-04	181	67	4	e2481291c236105774c53883e6f20da11941df9b
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYT1 FSD1 KIF5A PGAM2	1.59e-04	181	67	4	7f99002a6411117cc2361334c7c9228e20c574b4
ToppCell	Pericytes-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	ITGA11 MYH11 CCDC168 PLCB4	1.66e-04	183	67	4	d04deef7cd4e1738227a6593b84874ce0168c773
ToppCell	facs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 MYH11 SNCG ARHGEF17	1.66e-04	183	67	4	8d45dff06a199b1369576657f7f9dc0249c5f841
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 XIRP2 SNCG PGAM2	1.66e-04	183	67	4	6f5dbac2748f50105f0f548d189c42ef14287019
ToppCell	facs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 MYH11 SNCG ARHGEF17	1.66e-04	183	67	4	421265fa15d5a028cb567bb0904e670473ef102b
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF608 AHNAK CHD9 TASOR	1.70e-04	184	67	4	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT SYT1 FSD1 SNCG	1.73e-04	185	67	4	3d6711030ca4328357b06d5497cf98cdefcd7f4f
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPT KIF5A SNCG PGAM2	1.73e-04	185	67	4	110d5f02759c8235b14aea524ea47199696094ea
Computational	Intermediate filaments and MT.	MYH11 DSP MAPT KIF5A	1.37e-04	68	42	4	MODULE_438
Disease	Cleft palate, cleft lip, alcohol exposure measurement, parental genotype effect measurement	ANO2 ARHGEF10	4.91e-05	5	66	2	EFO_0003959, EFO_0005939, EFO_0009113, HP_0000175
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH1 MYH8	2.19e-04	10	66	2	DOID:0110454 (implicated_via_orthology)
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH1 MYH8	2.19e-04	10	66	2	DOID:0111269 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH1 MYH8	2.19e-04	10	66	2	DOID:0080719 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH1 MYH8	2.19e-04	10	66	2	DOID:0111602 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH1 MYH8	2.19e-04	10	66	2	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH1 MYH8	2.19e-04	10	66	2	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH1 MYH8	2.19e-04	10	66	2	DOID:0080326 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH1 MYH8	2.19e-04	10	66	2	DOID:0111596 (implicated_via_orthology)
Disease	Alzheimer's disease (implicated_via_orthology)	HSPD1 MAPT DNAJA4	2.87e-04	57	66	3	DOID:10652 (implicated_via_orthology)
Disease	distal myopathy (implicated_via_orthology)	MYH1 MYH8	3.21e-04	12	66	2	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH1 MYH8	3.21e-04	12	66	2	DOID:2106 (implicated_via_orthology)
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH1 MYH8	3.78e-04	13	66	2	DOID:397 (implicated_via_orthology)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH1 MYH8	5.08e-04	15	66	2	DOID:0050646 (implicated_via_orthology)
Disease	migraine disorder, Headache	MYO1A MAPT RNF213	9.58e-04	86	66	3	HP_0002315, MONDO_0005277
Disease	Glycogen Storage Disease	PGAM2 PGK1	1.67e-03	27	66	2	C0017919
Disease	susceptibility to rheumatic fever measurement	RYR3 CACNA2D3	1.79e-03	28	66	2	EFO_0008416

Protein segments in the cluster

Peptide	Gene	Start	Entry
MQKLVKAAKDGTKDG	ARHGEF10	346	O15013
ASKAGMVKKKGIAAK	CXorf66	76	Q5JRM2
MGKKQNGKSKKVEEA	CBX3	11	Q13185
DVEVQGKVKGSKFKM	AHNAK	3391	Q09666
KKKMLKGQGTFDGEE	ARHGEF26	361	Q96DR7
KKIIEVHVEKGMKDG	DNAJA4	206	Q8WW22
TKDDAMLLKGKGDKA	HSPD1	351	P10809
EGIGKKKKVVAVAAA	AHDC1	696	Q5TGY3
KEMYEIKAGGSIAKK	ANO2	211	Q9NQ90
KMGKKRIENFKSGVD	DHRS7	311	Q9Y394
KGKKSKVEVDELGMG	ARMCX2	296	Q7L311
KNELIEAFKQGMGKK	MKRN2	311	Q9H000
QEMVIEVKAIGGKKD	ARHGEF17	1291	Q96PE2
KVGIGEKKKVMGVLD	MYO1A	366	Q9UBC5
DAMGGKVQDIKAREK	FSD1	291	Q9BTV5
IAVTGEKKKDESGKM	MYH8	201	P13535
EKKKDESGKMQGTLE	MYH8	206	P13535
KDVKEAMKKVLGKGS	OR2W6P	301	Q8NHA6
AKMKVIEEEAKKQEG	PDE6C	821	P51160
MPKRKAKGDAKGDKA	HMGN4	1	O00479
LSEGKVKKNMGEGKK	GLYR1	131	Q49A26
VTGEKKKEEVTSGKM	MYH1	201	P12882
KGGRKGAKKVMIVIT	ITGA11	256	Q9UKX5
EGAKIVKDLMSKAEK	PGK1	261	P00558
KAKEGRMEAKDGSLK	GPR101	271	Q96P66
LFGEGKQKSKELKKM	KDM5A	1516	P29375
GSIIGKKGESVKKMR	PCBP2	26	Q15366
KKGESVKKMREESGA	PCBP2	31	Q15366
LVKKGKSKVGDMLEK	PCID2	126	Q5JVF3
GKQSEEEVKGSMKIK	CHD9	651	Q3L8U1
VDKAVKESGMEKVLK	DNAH17	1401	Q9UFH2
GKFSMEVKKTVDKGK	CACNA2D3	581	Q8IZS8
VKGKKKMSAAEAVKE	DSP	2701	P15924
IKKSKDMAKEAVGGQ	MAP7D3	631	Q8IWC1
EGALKEAKEGAMKDK	KIF5A	876	Q12840
GRGAEKTAAKMEKKV	KLHDC4	11	Q8TBB5
QKKMKKSKEGGTEEE	CCDC174	301	Q6PII3
TKMKELHQGKKGVDE	CCDC168	1741	Q8NDH2
KEEVKKFNMRSVKGG	DDX46	236	Q7L014
GKVNEGQKKKILEEM	CAMSAP2	1376	Q08AD1
KGSMKGKEKARAAKE	OTOF	1366	Q9HC10
KGQKKADSMEAKGVE	ARHGAP30	721	Q7Z6I6
KGGKNAINMKDVKDL	SYT1	96	P21579
EKTKEGVMYVGAKTK	SNCG	31	O76070
TVSGIKGEAKKEKGM	HHLA1	26	C9JL84
KSIVGMTKVKVGKED	SNX2	211	O60749
EKMKVVGAVDSGKRK	TIGD6	16	Q17RP2
MEGKELSKGQAKKLK	CARS1	711	P49589
EKILEKAMKKKGGSN	PLCB4	976	Q15147
QKKKLGGKDIFMTEE	SCN4A	1301	P35499
GAGINKLIMAKKKEV	SLC9C1	836	Q4G0N8
IFVNGKEIKGKMDAV	TMEM132C	491	Q8N3T6
EEAKRGAKAIKDAKM	PGAM2	36	P15259
MIEAIKESKNGKKIG	SUPT16H	121	Q9Y5B9
GDVVIFKIMKGKIKS	TASOR	236	Q9UK61
EDLGAKGAKEKMKEE	TBC1D9B	466	Q66K14
IVKDMGTDGKEELKA	CLSPN	556	Q9HAW4
GKKVTVGKDDIQKMN	MYH11	66	P35749
KEGVIKKDAKAVMAG	XIRP2	1766	A4UGR9
AVKGAGKEMKEKTQR	RNF213	281	Q63HN8
KTKDEMAAAEEKVGK	RNF213	316	Q63HN8
KTENKGKTGDEEMLK	TCEAL4	46	Q96EI5
KEMKSKENVKGGEKT	THOC2	1371	Q8NI27
KGIISKKEFQKAMEG	RYR3	3936	Q15413
KQGKRKAEKDEMVGA	SNX18	391	Q96RF0
MKVKEEKAGVGKLDH	SLC4A5	1	Q9BY07
EMKLKGADGKTKIAT	MAPT	456	P10636
KSKKMKEKSEEQGEG	ZC3H11B	221	A0A1B0GTU1
KGGKAKGKKTQMAEV	TOP2A	1196	P11388
KMDAKLGKLEDSKGA	ZNF608	831	Q9ULD9