Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	LRRC37AB_C	LRRC37A LRRC37A3 LRRC37A2	2.10e-07	4	71	3	PF14914
Domain	LRRC37_N	LRRC37A LRRC37A3 LRRC37A2	2.10e-07	4	71	3	IPR032754
Domain	LRRC37AB_C	LRRC37A LRRC37A3 LRRC37A2	2.10e-07	4	71	3	IPR029423
Domain	LRRC37	LRRC37A LRRC37A3 LRRC37A2	2.10e-07	4	71	3	PF15779
Domain	LRRC37A/B-like	LRRC37A LRRC37A3 LRRC37A2	2.10e-07	4	71	3	IPR015753
Domain	DEP_dom	RAPGEF3 DVL2 FMN2	8.83e-05	23	71	3	IPR000591
Domain	RasGAP_dom	PLXNB1 SYNGAP1	2.10e-03	18	71	2	IPR001936
Domain	DEP	RAPGEF3 DVL2	3.13e-03	22	71	2	PF00610
Domain	DEP	RAPGEF3 DVL2	3.13e-03	22	71	2	PS50186
Domain	-	HERC1 TECPR1	3.13e-03	22	71	2	2.130.10.30
Domain	DEP	RAPGEF3 DVL2	3.13e-03	22	71	2	SM00049
Domain	RCC1/BLIP-II	HERC1 TECPR1	3.42e-03	23	71	2	IPR009091
Domain	EGF_CA	NELL1 CRELD1 LTBP4	4.30e-03	86	71	3	PF07645
Domain	RASGEF	RAPGEF3 RAPGEFL1	4.37e-03	26	71	2	PS00720
Domain	RASGEF_CAT	RAPGEF3 RAPGEFL1	5.41e-03	29	71	2	PS50009
Domain	RasGEF	RAPGEF3 RAPGEFL1	5.79e-03	30	71	2	PF00617
Domain	-	RAPGEF3 RAPGEFL1	5.79e-03	30	71	2	1.10.840.10
Domain	Ras_GEF_dom	RAPGEF3 RAPGEFL1	5.79e-03	30	71	2	IPR023578
Domain	RASGEF_cat_dom	RAPGEF3 RAPGEFL1	5.79e-03	30	71	2	IPR001895
Domain	RasGEF	RAPGEF3 RAPGEFL1	5.79e-03	30	71	2	SM00147
Domain	EGF_Ca-bd_CS	NELL1 CRELD1 LTBP4	6.01e-03	97	71	3	IPR018097
Domain	Sema	SEMA4B PLXNB1	6.17e-03	31	71	2	SM00630
Domain	Semap_dom	SEMA4B PLXNB1	6.17e-03	31	71	2	IPR001627
Domain	Sema	SEMA4B PLXNB1	6.17e-03	31	71	2	PF01403
Domain	SEMA	SEMA4B PLXNB1	6.17e-03	31	71	2	PS51004
Domain	EGF_CA	NELL1 CRELD1 LTBP4	6.36e-03	99	71	3	PS01187
Domain	ASX_HYDROXYL	NELL1 CRELD1 LTBP4	6.54e-03	100	71	3	PS00010
Domain	PSI	SEMA4B PLXNB1	6.57e-03	32	71	2	PF01437
Domain	Plexin_repeat	SEMA4B PLXNB1	6.57e-03	32	71	2	IPR002165
Domain	MAGE	MAGEL2 MAGED1	7.39e-03	34	71	2	SM01373
Domain	EGF-type_Asp/Asn_hydroxyl_site	NELL1 CRELD1 LTBP4	7.68e-03	106	71	3	IPR000152
Domain	MAGE	MAGEL2 MAGED1	8.26e-03	36	71	2	PS50838
Domain	MAGE	MAGEL2 MAGED1	8.26e-03	36	71	2	PF01454
Domain	MHD_dom	MAGEL2 MAGED1	8.26e-03	36	71	2	IPR002190
Domain	EGF_CA	NELL1 CRELD1 LTBP4	1.13e-02	122	71	3	SM00179
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CNPPD1 SEMA4B NCOA6 SPHK2 URB1 KMT2B SZT2 KIF26A IRAK1 C15orf39 IRS2 HERC1 BRAT1 TESK1 LTBP4 HR	3.19e-09	1105	79	16	35748872
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A LRRC37A3 LRRC37A2	4.50e-08	4	79	3	22419166
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A LRRC37A3 LRRC37A2	1.34e-06	10	79	3	23064749
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	NCOA6 ZNF469 MAGEL2 MAGED1 TSPOAP1 MRPL43 TECPR1 SYNGAP1	6.20e-06	430	79	8	35044719
Pubmed	A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.	IRS2 EPAS1	1.53e-05	3	79	2	24037094
Pubmed	Insulin receptor substrate 1/2 (IRS1/2) regulates Wnt/β-catenin signaling through blocking autophagic degradation of dishevelled2.	DVL2 IRS2	3.05e-05	4	79	2	24616100
Pubmed	Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development.	MAGEL2 MAGED1	3.05e-05	4	79	2	18930956
Pubmed	MIIP inhibits clear cell renal cell carcinoma proliferation and angiogenesis via negative modulation of the HIF-2α-CYR61 axis.	HDAC6 EPAS1	5.07e-05	5	79	2	34931765
Pubmed	Glycosphingolipids are not pivotal receptors for Subtilase cytotoxin in vivo: sensitivity analysis with glycosylation-defective mutant mice.	B4GALNT1 CMAHP	5.07e-05	5	79	2	18996356
Pubmed	Discoidin domain receptor 1 tyrosine kinase has an essential role in mammary gland development.	DDR1 CSN2	5.07e-05	5	79	2	11283268
Pubmed	Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.	NCOA6 KMT2B	7.60e-05	6	79	2	17021013
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	URB1 LRRC37A LRRC37A3 GPRIN2	9.90e-05	105	79	4	9628581
Pubmed	A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4.	NCOA6 KMT2B	1.06e-04	7	79	2	19433796
Pubmed	ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.	NCOA6 KMT2B	1.06e-04	7	79	2	19556342
Pubmed	Semaphorin-Plexin Signaling Controls Mitotic Spindle Orientation during Epithelial Morphogenesis and Repair.	SEMA4B PLXNB1	1.82e-04	9	79	2	25892012
Pubmed	Formin 2 Regulates Lysosomal Degradation of Wnt-Associated β-Catenin in Neural Progenitors.	DVL2 FMN2	1.82e-04	9	79	2	29659741
Pubmed	Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase.	MAGEL2 MAGED1	2.76e-04	11	79	2	24911587
Pubmed	Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus.	DVL2 ATP1A1	2.76e-04	11	79	2	28746879
Pubmed	Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.	SEMA4B PLXNB1	3.31e-04	12	79	2	12123608
Pubmed	An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration.	SEMA4B PLXNB1	3.91e-04	13	79	2	24572910
Pubmed	Functional proteomics mapping of a human signaling pathway.	PIGQ NCOA6 KMT2B PLAGL1 HERC1 PDCD7 EPAS1	3.98e-04	591	79	7	15231748
Pubmed	A Pellino-2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium-digital keloid dysplasia.	DVL2 IRAK1	4.55e-04	14	79	2	36776133
Pubmed	A whole genome association study of mother-to-child transmission of HIV in Malawi.	DDR1 PLAGL1	4.55e-04	14	79	2	20487506
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	NCOA6 HDAC6 KMT2B CDH4	4.62e-04	157	79	4	30186101
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	GFI1B NELL1 MAGED1 KMT2B DVL2 LTBP4 C1orf94	4.71e-04	608	79	7	16713569
Pubmed	Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development.	SEMA4B PLXNB1	5.25e-04	15	79	2	21122816
Pubmed	Sox9 in mouse urogenital sinus epithelium mediates elongation of prostatic buds and expression of genes involved in epithelial cell migration.	EPAS1 HR	5.99e-04	16	79	2	31669249
Pubmed	SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.	NCOA6 KMT2B	5.99e-04	16	79	2	23870121
Pubmed	H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.	NCOA6 KMT2B	5.99e-04	16	79	2	24368734
Pubmed	MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.	NCOA6 KMT2B	6.78e-04	17	79	2	26180087
Pubmed	FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region.	TEDC2 PDCD7	7.61e-04	18	79	2	16484223
Pubmed	PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.	NCOA6 KMT2B	7.61e-04	18	79	2	17500065
Pubmed	An overview of the MAGE gene family with the identification of all human members of the family.	MAGEL2 MAGED1	7.61e-04	18	79	2	11454705
Pubmed	Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.	NCOA6 KMT2B	9.43e-04	20	79	2	19047629
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	NCOA6 KMT2B	1.14e-03	22	79	2	26886794
Pubmed	Renal developmental defects resulting from in utero hypoxia are associated with suppression of ureteric β-catenin signaling.	CDH4 EPAS1	1.14e-03	22	79	2	25587709
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NCOA6 AFAP1 SZT2 KIF26A SRCIN1 PLXNB1	1.31e-03	529	79	6	14621295
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	CRELD1 URB1 MAGED1 GHDC DVL2 IRAK1 ATP1A1 BRAT1	1.35e-03	942	79	8	31073040
Pubmed	Delineating WWOX Protein Interactome by Tandem Affinity Purification-Mass Spectrometry: Identification of Top Interactors and Key Metabolic Pathways Involved.	MAGED1 DVL2 IRAK1 ATP1A1	1.54e-03	217	79	4	30619736
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	AFAP1 DVL2 SRCIN1 SYNGAP1	1.56e-03	218	79	4	33378226
Pubmed	Stage-specific changes in gene expression in acutely isolated mouse CNS progenitor cells.	PLAGL1 FUT4	1.60e-03	26	79	2	15890332
Pubmed	Rebalancing gene haploinsufficiency in vivo by targeting chromatin.	KMT2B SALL4	1.85e-03	28	79	2	27256596
Pubmed	CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.	MAGED1 DVL2 IRAK1	1.94e-03	108	79	3	30166453
Pubmed	Disruption of parental-specific expression of imprinted genes in uniparental fetuses.	MAGEL2 PLAGL1	1.99e-03	29	79	2	16987518
Pubmed	Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction.	KIF26A UPK3B	2.27e-03	31	79	2	22282597
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	SPHK2 KMT2B KASH5 CD177 SIGLEC9 PRR19 MED25 LTBP4 ZNF541	2.10e-04	1192	79	9	chr19q13
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#3	DDR1 IRAK1 FMN2 PLAGL1 LTBP4 CDH4	2.69e-05	166	75	6	Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000_K3
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	AFAP1 SHF LRRC37A3 PRR19 HR GGT5	5.13e-07	166	79	6	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	AFAP1 SHF LRRC37A3 PRR19 HR GGT5	5.13e-07	166	79	6	7c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED1 CD177 KIF26A RAPGEF3 FUT4 CMAHP	9.06e-07	183	79	6	ee9c88be88221b7ad4ea9f890b17d6156fb3432e
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-Goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED1 CD177 KIF26A RAPGEF3 FUT4 CMAHP	9.06e-07	183	79	6	c52b84034503d931f7b87312d2ff86daff14152d
ToppCell	10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-HSC/MPP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	AMER1 FCRLB SALL4 CDH4 ETV3L	1.00e-05	161	79	5	46b5d80d2d521fb69752aba4c10383e715a32002
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD177 RAPGEF3 FCRLB MYL10 LTBP4	1.38e-05	172	79	5	a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDR1 SEMA4B GPR150 SCIMP CMAHP	1.42e-05	173	79	5	4f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDR1 SEMA4B GPR150 SCIMP CMAHP	1.42e-05	173	79	5	9bbea566964281f47bf75d665b7d69ba8326e207
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD177 RAPGEF3 FCRLB MYL10 LTBP4	1.54e-05	176	79	5	3494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCell	droplet-Liver-Npc-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD177 RAPGEF3 FCRLB MYL10 LTBP4	1.54e-05	176	79	5	d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGEL2 ZCCHC12 CDH4 GPRIN2 GGT5	1.67e-05	179	79	5	479116ac65488c60104a053530830763ec1f95b2
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGEL2 ZCCHC12 CDH4 GPRIN2 GGT5	1.67e-05	179	79	5	1dfc0cb8b369aef35c59f3d4c52603dc9f3728c1
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGEL2 ZCCHC12 CDH4 GPRIN2 GGT5	1.67e-05	179	79	5	69a1b3b05c921de6343ffe6ad998aa2b804312a7
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DDR1 SEMA4B ATP1A1 EPAS1 RAPGEFL1	1.96e-05	185	79	5	e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCell	proximal-Hematologic-Platelet/Megakaryocyte\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZNF469 AMER1 WDR97 TEDC2 FMN2	2.34e-05	192	79	5	522d1bb15edf1d6006b80289bd3baadb99584ae8
ToppCell	proximal-3-Hematologic-Platelet/Megakaryocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZNF469 AMER1 WDR97 TEDC2 FMN2	2.34e-05	192	79	5	f5f83dec37dff32a0c471cb05d23d13b0b0ad0c9
ToppCell	proximal-Hematologic-Platelet/Megakaryocyte-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZNF469 AMER1 WDR97 TEDC2 FMN2	2.34e-05	192	79	5	57899a905ca3e336bb7f31edc6418a2546b9891a
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED1 CD177 KIF26A RAPGEF3 FUT4	2.46e-05	194	79	5	0797245ebfa389a6f66874cb0f11297f1456e600
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-secretory_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED1 CD177 KIF26A RAPGEF3 FUT4	2.46e-05	194	79	5	0241b4b88d6210b4c1b8aa99db17115b18142f01
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	DDR1 CD177 LTBP4 PLXNB1 HR	2.65e-05	197	79	5	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	PIGQ PRR19 LRRC37A2 IRAK1 EPAS1	2.85e-05	200	79	5	0f4b8b0868bda406fe6bf01d1b722510fdfd0168
Drug	Ergocryptine-alpha [511-09-1]; Up 200; 7uM; MCF7; HT_HG-U133A	SPHK2 URB1 HDAC6 IRS2 LTBP4 EPAS1 HR	3.25e-06	194	74	7	3900_UP
Drug	Naringenine [480-41-1]; Up 200; 14.6uM; MCF7; HT_HG-U133A	PIGQ CNPPD1 SPHK2 KMT2B SZT2 PLAGL1 FUT4	3.36e-06	195	74	7	3278_UP
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; PC3; HT_HG-U133A	SPHK2 DVL2 MED25 IRS2 LTBP4 PLXNB1 FCMR	3.85e-06	199	74	7	4297_DN
Drug	Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; PC3; HT_HG-U133A	KMT2B SZT2 MED25 LTBP4 HR FCMR	3.94e-05	193	74	6	4322_UP
Drug	Atropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; MCF7; HT_HG-U133A	CRELD1 TSPOAP1 IRS2 LTBP4 GPRIN2 FCMR	4.17e-05	195	74	6	7219_UP
Drug	Cyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A	CNPPD1 SPHK2 AFAP1 HDAC6 SZT2 HR	4.17e-05	195	74	6	3268_UP
Drug	Papaverine hydrochloride [61-25-6]; Up 200; 10.6uM; MCF7; HT_HG-U133A	CRELD1 SPHK2 IRS2 TESK1 RAPGEFL1 HR	4.17e-05	195	74	6	6245_UP
Drug	Isosorbide dinitrate [87-33-2]; Down 200; 17uM; MCF7; HT_HG-U133A	AFAP1 SZT2 IRS2 LTBP4 RAPGEFL1 HR	4.17e-05	195	74	6	4742_DN
Drug	Cisapride [81098-60-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A	SPHK2 SZT2 MED25 IRS2 MYL10 GPRIN2	4.29e-05	196	74	6	3305_UP
Drug	Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A	CRELD1 TEDC2 PLAGL1 IRS2 FUT4 RAPGEFL1	4.29e-05	196	74	6	5307_UP
Drug	Isometheptene mucate; Down 200; 8.2uM; PC3; HT_HG-U133A	CNPPD1 SPHK2 URB1 MED25 EPAS1 FCMR	4.29e-05	196	74	6	5082_DN
Drug	Diprophylline [479-18-5]; Down 200; 15.8uM; PC3; HT_HG-U133A	SPHK2 URB1 AFAP1 TSPOAP1 DVL2 MED25	4.29e-05	196	74	6	5063_DN
Drug	Isosorbide dinitrate [87-33-2]; Up 200; 17uM; PC3; HT_HG-U133A	PIGQ CRELD1 SPHK2 URB1 MYL10 LTBP4	4.29e-05	196	74	6	3720_UP
Drug	Biperiden hydrochloride [1235-82-1]; Down 200; 11.4uM; PC3; HT_HG-U133A	URB1 KMT2B MED25 PLXNB1 HR FCMR	4.42e-05	197	74	6	4684_DN
Drug	15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A	CRELD1 SPHK2 SZT2 DVL2 MED25 PLAGL1	4.42e-05	197	74	6	7521_UP
Drug	Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Down 200; 11.8uM; MCF7; HT_HG-U133A	DVL2 FUT4 LTBP4 PLXNB1 RAPGEFL1 HR	4.54e-05	198	74	6	4133_DN
Drug	Nomifensine maleate [32795-47-4]; Down 200; 11.2uM; MCF7; HT_HG-U133A	PIGQ SPHK2 DVL2 PLAGL1 FUT4 HR	4.67e-05	199	74	6	2224_DN
Drug	Bemegride [64-65-3]; Up 200; 25.8uM; MCF7; HT_HG-U133A	PIGQ CNPPD1 MED25 PLAGL1 MYL10 TESK1	4.67e-05	199	74	6	3389_UP
Drug	Thalidomide [50-35-1]; Up 200; 15.4uM; PC3; HT_HG-U133A	SPHK2 URB1 B4GALNT1 CSN2 TEDC2 RAPGEFL1	4.67e-05	199	74	6	2095_UP
Disease	dystonia (is_implicated_in)	KMT2B TSPOAP1	5.39e-04	14	73	2	DOID:543 (is_implicated_in)
Disease	mean reticulocyte volume	PIGQ GFI1B SPHK2 ZNF469 IRAK1 C15orf39 IRS2 EPAS1	7.95e-04	799	73	8	EFO_0010701
Disease	lymphocyte percentage of leukocytes	GFI1B SPHK2 TSPOAP1 IRAK1 FCRLB PLAGL1 ZNF831	1.29e-03	665	73	7	EFO_0007993
Disease	erosive tooth wear measurement	KIF26A FMN2 CDH4	1.46e-03	90	73	3	EFO_0009331
Disease	monocyte count	GFI1B SZT2 TSPOAP1 FCRLB PLAGL1 IRS2 ATP1A1 CMAHP RAPGEFL1 GGT5	1.48e-03	1320	73	10	EFO_0005091
Disease	eye measurement	ZNF469 HERC1	2.04e-03	27	73	2	EFO_0004731

Protein segments in the cluster

Peptide	Gene	Start	Entry
NTQWPPDPPLHFGPT	EPAS1	636	Q99814
QPLPQRPSPWPQASL	BRAT1	376	Q6PJG6
PGLRLPLAPWAPPQS	B4GALNT1	31	Q00973
PLPEIPQPWLPPDSG	AFAP1	66	Q8N556
WPPGPPPTNFSSLEL	DDR1	386	Q08345
LPVGPGPAWISPNQL	AMER1	966	Q5JTC6
SLPLWAPQPPADPGS	CD177	116	Q8N6Q3
LNQPLWLNLNYPPPP	C1orf94	456	Q6P1W5
PPPELSLSLPFPIQW	CBLL2	211	Q8N7E2
LAPLPGATPWPLLPT	DVL2	536	O14641
ETLPLPPSWPPGPAL	TSPOAP1	286	O95153
LSVLLLGPSPPPTWP	KASH5	536	Q8N6L0
LNLPGPIWLQPSPPP	CRELD1	21	Q96HD1
PLQLTSNPLGPPEPW	LRRC37A3	46	O60309
NPPGAPPNVLWQTPL	MAGED1	286	Q9Y5V3
VLATQPPLWQALPPP	MAGEL2	506	Q9UJ55
EVPTLPLQPSWQAPP	MAGEL2	676	Q9UJ55
PLQLTSNPLGPPDSW	LRRC37A2	46	A6NM11
PLQLTSNPLGPPESW	LRRC37A	46	A6NMS7
CWGQLPPLPWASPTP	FUT4	171	P22083
LWPPALTPVPRDQAP	GFI1B	26	Q5VTD9
GPNALTPPPTTPEWI	ATP1A1	76	P05023
IDPAGLPLPQPAQSW	HERC1	1121	Q15751
PPGALLWLQEPQPCP	HR	841	O43593
NFVPQGWVLPPLPSN	PDCD7	461	Q8N8D1
IPPITTRALWPPDPQ	PLXNB1	181	O43157
LTSPWPRPLPWPGNT	GHDC	156	Q8N2G8
SGVLQLWPPPAPPCL	KIF26A	341	Q9ULI4
AQSWPAQLPPRAPLP	MED25	701	Q71SY5
SWTLPPGPLLGVLPV	KMT2B	2231	Q9UMN6
VSNSWPQVILPPRPP	MYL10	6	Q9BUA6
PELGLVPSPASLWPP	IRAK1	156	P51617
DPPDTNLPPGINLWL	NELL1	176	Q92832
PGWNQLPSGALQPPP	NCOA6	316	Q14686
QLQPAPPLAPQGRPW	IRS2	1206	Q9Y4H2
PWPGTTQPPSPQLLR	FAM157B	266	P0CG42
PWPWSPVLLSLPQPQ	CNPPD1	376	Q9BV87
SQPPLGPFLPLTWPS	C18orf15	71	Q96N68
WPPTGITPLNPLEVP	MT-CO3	116	P00414
PIPQTLALPPQPLWS	CSN2	156	P05814
PPPKDTLLPWPQHQN	CDH4	146	P55283
TEPLRPQDPLPWPAL	GGT5	206	P36269
RPGPELPLPSIPAWT	LTBP4	521	Q8N2S1
LPLPSIPAWTGPEIP	LTBP4	526	Q8N2S1
SLWAPLSPGQPLVPE	FAM186A	1851	A6NE01
PWLQLPGPGSPLDPA	FCRLB	281	Q6BAA4
EGPWEPPVLPILTWP	HDAC6	461	Q9UBN7
LPPPLPSNWTCLSGP	ETV3L	236	Q6ZN32
PEPGPWAPLSPRLQP	GPRIN2	6	O60269
PPPPSLLWSAGQGQP	FMN2	811	Q9NZ56
LPAPVPGANSIPWVL	SALL4	201	Q9UJQ4
LALWPPSSPGPPDPL	SZT2	2311	Q5T011
PQILLPGWPDPPDLP	MRPL43	166	Q8N983
SPLLGFWQLPPPATQ	PLAGL1	381	Q9UM63
SPVQLPPLPPRNWPS	SCIMP	76	Q6UWF3
LLPLVSAAQPQGPPW	TEDC2	391	Q7L2K0
PPAPNISVPILLGWG	GPR150	11	Q8NGU9
AHLPPPQLWLPPQAL	PIGQ	521	Q9BRB3
QPPPPTWALSPRISL	SEMA4B	36	Q9NPR2
PSQPSNPGVLELPWV	SIGLEC9	296	Q9Y336
FPPPSTPPWELLQAQ	TEX45	86	Q8NA69
WLLQAQGSPSPPALP	URB1	871	O60287
PQTTQGPWEPLALAP	ANHX	251	E9PGG2
ELNPPNPWDLQPRSP	CMAHP	11	Q9Y471
PSSPWTQLAQPLGPP	C15orf39	246	Q6ZRI6
ALWTSPPPGSFLQPP	NDUFV1-DT	226	Q8NBR9
GLSLPGSAWQPPPLP	ZNF503-AS2	101	A6NEH8
LPVWLPNQDEPLPGS	RAPGEF3	536	O95398
LPWPPPVGQLDSSPS	SHF	226	Q7M4L6
PPLGTPLPPDWVTLE	SPHK2	521	Q9NRA0
EGVWPPPNNLLSQSP	SRCIN1	831	Q9C0H9
PLGPTNPRVTLAPPW	SYNGAP1	1301	Q96PV0
WGVGLPQPLPQPSSP	PRR19	301	A6NJB7
LGLVVPAAQPPPSWQ	WDR97	846	A6NE52
PGPAPTPAELPWTNI	TECPR1	476	Q7Z6L1
PLPPAPLQVSESPWL	FCMR	341	O60667
LPPSPESPPNWGDNL	TESK1	361	Q15569
GPPPARLPQLWDPTA	ZNF469	431	Q96JG9
LPQSAPLPWPQVLPT	ZNF469	476	Q96JG9
PLPWPQVLPTARPSP	ZNF469	481	Q96JG9
PQAETPLPLPIPWGP	ZNF831	946	Q5JPB2
LSPGEPLTSPPWAPL	RAPGEFL1	131	Q9UHV5
GLQAWPGPPPQPQPL	UPK3B	291	Q9BT76
ESQDPPLPSWGAPPL	ZCCHC12	281	Q6PEW1
RPLQGPWPQQPPPLA	ZNF541	591	Q9H0D2