Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

DES LRPPRC KIF3B CENPE MYO7A CEP135 GOLGA8B DAAM2 IQCJ-SCHIP1 KIFC3 TRAK2 DAAM1 TUBGCP2 EPB41L4A UTRN DCP1A

4.33e-0610997816GO:0008092
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF3B CENPE MYO7A KIFC3 DNAH5

9.90e-05118785GO:0003774
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF3B CENPE KIFC3 DNAH5

1.62e-0470784GO:0003777
GeneOntologyMolecularFunctionmicrotubule binding

LRPPRC KIF3B CENPE CEP135 GOLGA8B KIFC3 TUBGCP2

2.01e-04308787GO:0008017
GeneOntologyBiologicalProcessmicrotubule-based movement

LRPPRC CCNYL1 KIF3B CENPE CCDC146 KIFC3 TRAK2 BSN DNAH5 ODAD3

1.63e-054937810GO:0007018
GeneOntologyBiologicalProcessmicrotubule-based process

LRPPRC CCNYL1 KIF3B CENPE CCDC146 CEP135 NINL GOLGA8B KIFC3 TRAK2 TUBGCP2 BSN DNAH5 ODAD3

3.79e-0510587814GO:0007017
GeneOntologyBiologicalProcessDNA replication-dependent chromatin disassembly

ING5 ING4

4.23e-053782GO:0140889
GeneOntologyBiologicalProcessorganelle assembly

KIF3B FEZ2 CENPE MYO7A CCDC146 CBY1 CEP135 ATG2B GOLGA8B PRKDC TUBGCP2 DNAH5 ODAD3 DDX6

8.32e-0511387814GO:0070925
GeneOntologyCellularComponentmicrotubule organizing center

FAM184A KIF3B LRRC45 CCDC146 GLG1 CBY1 CEP135 NINL PRKAR2A KIFC3 DAAM1 TUBGCP2 ODAD3

3.28e-059197813GO:0005815
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

KIF3B CFAP36 PRKAR2A TRAK2 BSN DNAH5 ODAD3

1.81e-04317787GO:0032838
GeneOntologyCellularComponenttype III intermediate filament

DES PRPH

2.04e-046782GO:0045098
GeneOntologyCellularComponentcytoplasmic region

KIF3B CFAP36 PRKAR2A TRAK2 BSN DNAH5 ODAD3

3.92e-04360787GO:0099568
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

DES LRPPRC KIF3B CENPE NINL GOLGA8B KIFC3 TUBGCP2 DNAH5 DDX6 PRPH

4.88e-048997811GO:0099513
GeneOntologyCellularComponentprotein acetyltransferase complex

ING5 ING4 MCRS1 NAA16

6.22e-04104784GO:0031248
GeneOntologyCellularComponentacetyltransferase complex

ING5 ING4 MCRS1 NAA16

7.42e-04109784GO:1902493
GeneOntologyCellularComponentmicrotubule

LRPPRC KIF3B CENPE NINL GOLGA8B KIFC3 TUBGCP2 DNAH5

8.31e-04533788GO:0005874
GeneOntologyCellularComponentnpBAF complex

SMARCC1 SMARCC2

1.21e-0314782GO:0071564
GeneOntologyCellularComponentbrahma complex

SMARCC1 SMARCC2

1.21e-0314782GO:0035060
GeneOntologyCellularComponentRSC-type complex

SMARCC1 SMARCC2

1.40e-0315782GO:0016586
GeneOntologyCellularComponentnBAF complex

SMARCC1 SMARCC2

1.59e-0316782GO:0071565
GeneOntologyCellularComponentcilium

KIF3B MYO7A CFAP36 CBY1 PRKAR2A DAAM1 DNAH5 ODAD3 DDX6 PRPH

1.82e-038987810GO:0005929
DomainSMARCC_C

SMARCC1 SMARCC2

1.77e-052792IPR032451
DomainSMARCC_N

SMARCC1 SMARCC2

1.77e-052792IPR032450
DomainSWIRM-assoc

SMARCC1 SMARCC2

1.77e-052792IPR032448
DomainSWIRM-assoc_2

SMARCC1 SMARCC2

1.77e-052792PF16496
DomainSWIRM-assoc_1

SMARCC1 SMARCC2

1.77e-052792PF16495
DomainSWIRM-assoc_3

SMARCC1 SMARCC2

1.77e-052792PF16498
DomainING

ING5 ING4

1.75e-045792SM01408
DomainING_N_histone_binding

ING5 ING4

1.75e-045792IPR024610
DomainING

ING5 ING4

1.75e-045792PF12998
DomainING_fam

ING5 ING4

1.75e-045792IPR028651
DomainSWIRM

SMARCC1 SMARCC2

2.62e-046792PS50934
DomainSWIRM

SMARCC1 SMARCC2

2.62e-046792PF04433
DomainSWIRM

SMARCC1 SMARCC2

2.62e-046792IPR007526
Domain-

DAAM2 FRYL PRKDC DAAM1 HEATR3 XPOT

3.56e-042227961.25.10.10
DomainFilament_head

DES PRPH

3.66e-047792PF04732
DomainIntermed_filament_DNA-bd

DES PRPH

3.66e-047792IPR006821
DomainDAD_dom

DAAM2 DAAM1

4.87e-048792IPR014767
DomainDAD

DAAM2 DAAM1

4.87e-048792PS51231
DomainDrf_GBD

DAAM2 DAAM1

6.24e-049792PF06371
DomainFH3_dom

DAAM2 DAAM1

6.24e-049792IPR010472
DomainGTPase-bd

DAAM2 DAAM1

6.24e-049792IPR010473
DomainDrf_FH3

DAAM2 DAAM1

6.24e-049792PF06367
DomainDrf_FH3

DAAM2 DAAM1

6.24e-049792SM01139
DomainDrf_GBD

DAAM2 DAAM1

6.24e-049792SM01140
DomainKinesin_motor_CS

KIF3B CENPE KIFC3

6.92e-0441793IPR019821
DomainKinesin-like_fam

KIF3B CENPE KIFC3

7.96e-0443793IPR027640
DomainKINESIN_MOTOR_1

KIF3B CENPE KIFC3

8.51e-0444793PS00411
Domain-

KIF3B CENPE KIFC3

8.51e-04447933.40.850.10
DomainKinesin_motor_dom

KIF3B CENPE KIFC3

8.51e-0444793IPR001752
DomainKinesin

KIF3B CENPE KIFC3

8.51e-0444793PF00225
DomainKINESIN_MOTOR_2

KIF3B CENPE KIFC3

8.51e-0444793PS50067
DomainKISc

KIF3B CENPE KIFC3

8.51e-0444793SM00129
DomainGBD/FH3_dom

DAAM2 DAAM1

9.48e-0411792IPR014768
DomainGBD_FH3

DAAM2 DAAM1

9.48e-0411792PS51232
DomainARM-like

DAAM2 FRYL PRKDC DAAM1 HEATR3 XPOT

9.93e-04270796IPR011989
DomainFH2

DAAM2 DAAM1

1.79e-0315792PS51444
DomainFH2_Formin

DAAM2 DAAM1

1.79e-0315792IPR015425
DomainFH2

DAAM2 DAAM1

1.79e-0315792PF02181
DomainFH2

DAAM2 DAAM1

1.79e-0315792SM00498
DomainARM-type_fold

DAAM2 FRYL PRKDC DAAM1 HEATR3 XPOT

3.13e-03339796IPR016024
DomainPrefoldin

UACA CEP135 TRAK2

3.52e-0372793IPR009053
DomainPentatricopeptide_repeat

LRPPRC PRKDC

4.22e-0323792IPR002885
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

LRPPRC KIF3B UACA CENPE N4BP2 NGEF SMARCC1 PRKAR2A GOLGA8B SMARCC2 BSN HOMER3 RASAL2 EPM2AIP1

4.62e-08963811428671696
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

UACA CENPE CEP135 SMARCC1 PRKAR2A SMARCC2 MCRS1 TFIP11 PRKDC KIFC3 TUBGCP2 TRIM29 HOMER3 DDX6 NAA16

6.30e-081155811520360068
Pubmed

Defining the membrane proteome of NK cells.

EPRS1 LRPPRC KIF3B GALNT1 CENPE GLG1 POLD1 PRKAR2A PRKDC DAAM1 TUBGCP2 DDX6 DCP1A GNPAT PRPH

7.29e-081168811519946888
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

PPFIBP1 NINL SRPRA FRYL PRKDC TUBGCP2 UTRN SH3RF3 RASAL2 DDX6

9.07e-08446811024255178
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

DMGDH SETDB1 LRPPRC KIF3B MYO7A GLG1 CFAP36 NINL GMDS DAAM2 FRYL RIPK4 TRIM29 SNAP47 RASAL2

1.61e-071242811530973865
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

SETDB1 LRPPRC CCNYL1 KIF3B MYO7A PPFIBP1 POLD1 CBY1 ATG2B NINL SNAP47 SH3RF3 EXOSC4 RASAL2 DCP1A

3.53e-071321811527173435
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

LRPPRC UACA PPFIBP1 CBY1 DAAM1 SNAP47 UTRN RASAL2 PTK7

6.19e-0742181936976175
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

EPRS1 GTF2E1 LRPPRC GLG1 PPFIBP1 POLD1 SMARCC1 SMARCC2 GMDS SRPRA TFIP11 PRKDC EXOSC4 DDX6 XPOT

8.38e-071415811528515276
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

LRPPRC UACA COQ8A PPFIBP1 POLD1 ING5 ING4 SRPRA PRKDC TUBGCP2 SNAP47 HEATR3 DDX6 DCP1A XPOT

1.04e-061440811530833792
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

EPRS1 SETDB1 PPFIBP1 NGEF DAAM2 MCRS1 TFIP11 RIPK4 PRKDC KIFC3 UTRN DKK3 RASAL2 XPOT

1.49e-061285811435914814
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

LRPPRC FAM184A UACA GLG1 PPFIBP1 N4BP2 POLD1 PRKAR2A GMDS SRPRA TFIP11 DAAM1 SNAP47 RASAL2 PTK7

1.55e-061487811533957083
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

EPRS1 LRPPRC COQ8A POLD1 SMARCC1 PRKAR2A PRKDC TUBGCP2 DDX6 XPOT

2.35e-06638811033239621
Pubmed

Canonical Notch signaling plays an instructive role in auditory supporting cell development.

MYO7A DAAM2 DKK3

2.64e-061281326786414
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

EPRS1 COQ8A PPFIBP1 SMARCC1 SRPRA TFIP11 HEATR3 RASAL2 PTK7 GNPAT

2.77e-06650811038777146
Pubmed

ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

ING5 SMARCC1 SMARCC2 ING4

2.86e-064281416387653
Pubmed

Intestinal Paneth cell differentiation relies on asymmetric regulation of Wnt signaling by Daam1/2.

DAAM2 DAAM1

5.36e-06281238000028
Pubmed

The Swi3 protein plays a unique role in regulating respiration in eukaryotes.

SMARCC1 SMARCC2

5.36e-06281227190130
Pubmed

Lafora disease E3 ubiquitin ligase malin is recruited to the processing bodies and regulates the microRNA-mediated gene silencing process via the decapping enzyme Dcp1a.

NHLRC1 DCP1A

5.36e-06281223131811
Pubmed

Identification of chick and mouse Daam1 and Daam2 genes and their expression patterns in the central nervous system.

DAAM2 DAAM1

5.36e-06281215464228
Pubmed

Mutations in NHLRC1 cause progressive myoclonus epilepsy.

NHLRC1 EPM2AIP1

5.36e-06281212958597
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

LRPPRC COQ8A GLG1 SMARCC1 SRPRA TUBGCP2 HEATR3 GNPAT XPOT

6.36e-0656081935241646
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

EPRS1 COQ8A PRKAR2A GMDS PRKDC DDX6 DCP1A GNPAT XPOT

7.43e-0657181937167062
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

FAM184A UACA GLG1 PPFIBP1 POLD1 PRKAR2A MCRS1 SRPRA TFIP11 DAAM1 UTRN HOMER3 EXOSC4 DDX6

8.61e-061497811431527615
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

PPFIBP1 ATG2B TRAK2 UTRN RASAL2 DCP1A

9.77e-0620981636779422
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

LRPPRC POLD1 SMARCC1 PRKDC TUBGCP2 XPOT

1.03e-0521181617314511
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

LRPPRC COQ8A POLD1 ATG2B TUBGCP2 SNAP47 EXOSC4 DCP1A XPOT

1.19e-0560681936538041
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

EPRS1 LRPPRC GLG1 ATG2B PRKAR2A SMARCC2 SRPRA DAAM1 BSN TRIM29 SNAP47 PTK7

1.27e-051139811236417873
Pubmed

Abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in Lafora disease.

NHLRC1 EPM2AIP1

1.60e-05381228536304
Pubmed

Molecular characterization of mouse lens epithelial cell lines and their suitability to study RNA granules and cataract associated genes.

DDX6 DCP1A

1.60e-05381225530357
Pubmed

CCDC151 mutations cause primary ciliary dyskinesia by disruption of the outer dynein arm docking complex formation.

DNAH5 ODAD3

1.60e-05381225192045
Pubmed

EBNA3C attenuates the function of p53 through interaction with inhibitor of growth family proteins 4 and 5.

ING5 ING4

1.60e-05381221177815
Pubmed

BAF chromatin remodeling complex: cortical size regulation and beyond.

SMARCC1 SMARCC2

1.60e-05381223974113
Pubmed

Myosin VIIa participates in opsin transport through the photoreceptor cilium.

MYO7A PRPH

1.60e-05381210414956
Pubmed

Identification and comparative expression analyses of Daam genes in mouse and Xenopus.

DAAM2 DAAM1

1.60e-05381215533824
Pubmed

A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.

ING5 SMARCC1 ING4 DAAM1

1.66e-056581427453043
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

DES EPRS1 LRPPRC SMARCC2 PRKDC DAAM1 TRIM29 ITIH2 XPOT

2.00e-0564781926618866
Pubmed

Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.

KIF3B CENPE KIFC3

2.70e-05258139275178
Pubmed

DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly.

DES DAAM2 DAAM1

3.04e-052681326526197
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

EPRS1 LRPPRC UACA POLD1 WDR87 SMARCC1 PRKAR2A SMARCC2 TFIP11 PRKDC DDX6 DCP1A

3.09e-051247811227684187
Pubmed

P-body loss is concomitant with formation of a messenger RNA storage domain in mouse oocytes.

DDX6 DCP1A

3.20e-05481220075394
Pubmed

Hbo1 Links p53-dependent stress signaling to DNA replication licensing.

ING5 ING4

3.20e-05481217954561
Pubmed

p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity.

ING5 ING4

3.20e-05481212750254
Pubmed

mRNA decapping factor Dcp1a is essential for embryonic growth in mice.

DDX6 DCP1A

3.20e-05481233813271
Pubmed

Disheveled-associated activator of morphogenesis 2 promotes invasion of colorectal cancer by activating PAK1 and promoting MMP7 expression.

DAAM2 DAAM1

3.20e-05481233974241
Pubmed

Mammalian microtubule P-body dynamics are mediated by nesprin-1.

DDX6 DCP1A

3.20e-05481224862572
Pubmed

Type III Intermediate Filaments Desmin, Glial Fibrillary Acidic Protein (GFAP), Vimentin, and Peripherin.

DES PRPH

3.20e-05481229196434
Pubmed

The tumor suppressor hSNF5/INI1 modulates cell growth and actin cytoskeleton organization.

SMARCC1 SMARCC2

3.20e-05481215150092
Pubmed

Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.

LRPPRC GLG1 PPFIBP1 FRYL PRKDC

3.31e-0515681522952844
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

EPRS1 LRPPRC UACA PPFIBP1 SRPRA PRKDC TUBGCP2 TRIM29 EXOSC4 ITIH2 RASAL2 DDX6

3.34e-051257811236526897
Pubmed

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment.

DES GOLGA8B PTK7

3.42e-052781330516471
Pubmed

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

C22orf23 LRRC45 COQ8A CCDC146 GMDS MCRS1 TFIP11 KIFC3 TRIM29 HOMER3 DDX6 DCP1A EPM2AIP1

3.53e-051477811331515488
Pubmed

p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.

EPRS1 GLG1 SRPRA FRYL UTRN

3.63e-0515981530581152
Pubmed

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

LRPPRC GLG1 SMARCC1 SMARCC2 RASAL2

3.97e-0516281514743216
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

EPRS1 GALNT1 COQ8A FEZ2 GLG1 SMARCC1 TFIP11 FRYL UTRN DCP1A XPOT

4.23e-051084811111544199
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

EPRS1 LRPPRC N4BP2 FRYL PRKDC EXOSC4 DDX6 PRPH

4.40e-0555181834728620
Pubmed

The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.

KIF3B MCRS1 UTRN

4.72e-053081330480076
Pubmed

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.

EPRS1 LRPPRC SMARCC1 SMARCC2 UTRN EXOSC4 RASAL2

5.01e-0541181736652389
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

SETDB1 CENPE N4BP2 CEP135 SRPRA TFIP11 TUBGCP2 SNAP47 DCP1A

5.27e-0573381934672954
Pubmed

Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome.

SMARCC1 SMARCC2

5.33e-0558129693044
Pubmed

Regulating SWI/SNF subunit levels via protein-protein interactions and proteasomal degradation: BAF155 and BAF170 limit expression of BAF57.

SMARCC1 SMARCC2

5.33e-05581216199878
Pubmed

Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes.

SMARCC1 SMARCC2

5.33e-05581212244326
Pubmed

Members of the hSWI/SNF chromatin remodeling complex associate with and are phosphorylated by protein kinase B/Akt.

SMARCC1 SMARCC2

5.33e-05581216568092
Pubmed

The HSA domain of BRG1 mediates critical interactions required for glucocorticoid receptor-dependent transcriptional activation in vivo.

SMARCC1 SMARCC2

5.33e-05581218086889
Pubmed

p300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexes.

SMARCC1 SMARCC2

5.33e-0558129584200
Pubmed

Conserved molecular interactions within the HBO1 acetyltransferase complexes regulate cell proliferation.

ING5 ING4

5.33e-05581222144582
Pubmed

Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1.

DAAM2 DAAM1

5.33e-05581211779461
Pubmed

ROR1 is essential for proper innervation of auditory hair cells and hearing in humans and mice.

MYO7A PRPH

5.33e-05581227162350
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SETDB1 UACA COQ8A CFAP36 POLD1 ING5 SMARCC1 SMARCC2 ING4 MCRS1 TUBGCP2

5.50e-051116811131753913
Pubmed

The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking.

LRPPRC NINL PRKDC HOMER3 GNPAT

6.05e-0517781526485645
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

EPRS1 LRPPRC GALNT1 PRKAR2A SRPRA PRKDC TUBGCP2 HEATR3 PTK7 XPOT

6.69e-05942811031073040
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

EPRS1 LRPPRC POLD1 SMARCC1 SMARCC2 TFIP11 PRKDC UTRN RASAL2 DDX6 DCP1A XPOT

6.77e-051353811229467282
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

EPRS1 PRKDC ITIH2 HEATR3 XPOT

7.08e-0518381523956138
Pubmed

Variations in the composition of mammalian SWI/SNF chromatin remodelling complexes.

SMARCC1 SMARCC2

7.99e-05681219650111
Pubmed

Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex.

SMARCC1 SMARCC2

7.99e-05681216940996
Pubmed

Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression.

SMARCC1 SMARCC2

7.99e-05681221095589
Pubmed

Wnt antagonist gene polymorphisms and renal cancer.

DAAM2 DKK3

7.99e-05681219562778
Pubmed

The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.

SMARCC1 SMARCC2

7.99e-05681216230384
Pubmed

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer.

SMARCC1 SMARCC2

7.99e-05681210943845
Pubmed

DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa.

DDX6 DCP1A

7.99e-05681219966221
Pubmed

Varying modulation of HIV-1 LTR activity by Baf complexes.

SMARCC1 SMARCC2

7.99e-05681221699904
Pubmed

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase.

FEZ2 MYO7A NGEF GOLGA8B SNAP47 DDX6 GNPAT

9.21e-0545381727113764
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

UACA COQ8A TUBGCP2 XPOT

1.05e-0410481431240132
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

EPRS1 LRPPRC GLG1 SMARCC2 DAAM2 PRKDC UTRN DDX6 XPOT

1.10e-0480781930575818
Pubmed

Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter.

SMARCC1 SMARCC2

1.12e-04781216601680
Pubmed

Mice deficient in the chemokine receptor CXCR4 exhibit impaired limb innervation and myogenesis.

DES PRPH

1.12e-04781216198599
Pubmed

BRIT1/MCPH1 links chromatin remodelling to DNA damage response.

SMARCC1 SMARCC2

1.12e-04781219525936
Pubmed

Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths.

POTEB3 POTED

1.12e-04781215276201
Pubmed

ING4 and ING5 are essential for histone H3 lysine 14 acetylation and epicardial cell lineage development.

ING5 ING4

1.12e-04781238446206
Pubmed

ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.

ING5 ING4

1.12e-04781216728974
Pubmed

Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes.

SMARCC1 SMARCC2

1.12e-04781228369036
Pubmed

Target genes of the largest human SWI/SNF complex subunit control cell growth.

SMARCC1 SMARCC2

1.12e-04781221118156
Pubmed

Mov10 and APOBEC3G localization to processing bodies is not required for virion incorporation and antiviral activity.

DDX6 DCP1A

1.12e-04781223926332
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

EPRS1 LRPPRC MYO7A NGEF PRKAR2A SMARCC2 BSN SNAP47 UTRN HOMER3 RASAL2 DDX6

1.15e-041431811237142655
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

COQ8A MYO7A SMARCC1 SMARCC2 MCRS1 BSN HOMER3 RASAL2

1.22e-0463881831182584
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

EPRS1 LRPPRC PPFIBP1 N4BP2 NINL SMARCC1 PRKDC TUBGCP2

1.23e-0463981823443559
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

LRPPRC SMARCC1 SMARCC2 SRPRA PRKDC DDX6 PRPH

1.42e-0448681730940648
Pubmed

Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.

EPRS1 LRPPRC PRKDC XPOT

1.45e-0411381430352685
Pubmed

CHD7 cooperates with PBAF to control multipotent neural crest formation.

SMARCC1 SMARCC2

1.49e-04881220130577
Pubmed

The assembly of mammalian SWI/SNF chromatin remodeling complexes is regulated by lysine-methylation dependent proteolysis.

SMARCC1 SMARCC2

1.49e-04881236335117
Pubmed

Epigenetic regulation by BAF (mSWI/SNF) chromatin remodeling complexes is indispensable for embryonic development.

SMARCC1 SMARCC2

1.49e-04881226986003
InteractionKANK2 interactions

FAM184A PPFIBP1 NINL MCRS1 TFIP11 RIPK4 KIFC3 EPB41L4A HOMER3 DCP1A

2.12e-072858110int:KANK2
InteractionGIGYF1 interactions

CBY1 CEP135 NINL MCRS1 KIFC3 SH3RF3 RASAL2 DDX6

5.63e-07177818int:GIGYF1
InteractionDRAP1 interactions

GTF2E1 FEZ2 SMARCC1 SMARCC2 MCRS1 EPB41L4A

8.92e-0781816int:DRAP1
InteractionMCC interactions

EPRS1 UACA LRRC45 CCDC146 CBY1 MCRS1 KIFC3 RASAL2

2.43e-06215818int:MCC
InteractionPCNT interactions

FAM184A POLD1 CEP135 ING5 NINL PRKAR2A TUBGCP2 UTRN

5.65e-06241818int:PCNT
InteractionPPP1R13B interactions

FAM184A CEP135 NINL MCRS1 KIFC3 EPB41L4A PRPH

6.94e-06176817int:PPP1R13B
InteractionTPTE interactions

LRPPRC SRPRA PRKDC HEATR3 PTK7 XPOT

1.34e-05129816int:TPTE
InteractionKIF20A interactions

DES LRPPRC UACA CENPE PPFIBP1 CEP135 SMARCC2 TFIP11 PRKDC KIFC3 TUBGCP2 TRIM29 UTRN AGBL3 PRPH

1.68e-0510528115int:KIF20A
InteractionLNX1 interactions

PPFIBP1 CBY1 TFIP11 MSANTD4 PRKDC KIFC3 SNAP47 HOMER3 EXOSC4 EPM2AIP1 PRPH

4.50e-056348111int:LNX1
InteractionMOV10 interactions

DES SETDB1 LRPPRC CCNYL1 KIF3B GALNT1 COQ8A PPFIBP1 N4BP2 ING5 SMARCC1 SMARCC2 TFIP11 TRIM29 DDX6 DCP1A

4.96e-0512978116int:MOV10
InteractionCNTROB interactions

CEP135 MCRS1 BSN SNAP47 DCP1A EPM2AIP1

5.56e-05166816int:CNTROB
InteractionPROSER3 interactions

CCDC146 CEP135 NINL

5.79e-0519813int:PROSER3
InteractionINSYN1 interactions

UACA CCDC146 CEP135 MCRS1 SNAP47 UTRN

6.14e-05169816int:INSYN1
InteractionSIPA1L1 interactions

POLD1 CBY1 CEP135 NINL SH3RF3 RASAL2

7.22e-05174816int:SIPA1L1
InteractionSYNM interactions

DES CEP135 PRKAR2A PRPH

8.71e-0558814int:SYNM
InteractionGIGYF2 interactions

CBY1 NINL PRKAR2A SH3RF3 EXOSC4 RASAL2 DDX6

9.09e-05263817int:GIGYF2
InteractionNINL interactions

LRPPRC FAM184A CENPE CCDC146 NINL PRKDC TUBGCP2 HOMER3 GNPAT

9.16e-05458819int:NINL
InteractionDCTN2 interactions

COQ8A N4BP2 POLD1 NINL SMARCC1 SMARCC2 KIFC3 EXOSC4

9.18e-05356818int:DCTN2
InteractionDUSP26 interactions

LRPPRC ATG2B PTK7 XPOT

9.32e-0559814int:DUSP26
InteractionPOTED interactions

POTEB3 POTED

9.52e-054812int:POTED
InteractionPRPF18 interactions

NINL DAAM2 TFIP11 KIFC3 DAAM1

1.23e-04120815int:PRPF18
InteractionCEP192 interactions

FAM184A POLD1 CEP135 NINL HOMER3 DCP1A

1.24e-04192816int:CEP192
InteractionVPS52 interactions

FAM184A CCDC146 NINL KIFC3 DDX6 EPM2AIP1

1.35e-04195816int:VPS52
InteractionMAP7D3 interactions

CBY1 CEP135 NINL RIPK4 TRAK2

1.38e-04123815int:MAP7D3
InteractionGPR17 interactions

SETDB1 PPFIBP1 TFIP11 PRKDC TUBGCP2 HEATR3 XPOT

1.43e-04283817int:GPR17
InteractionCSNK1A1 interactions

POTEB3 CBY1 CEP135 NINL RIPK4 PRKDC RASAL2 EPM2AIP1

1.46e-04381818int:CSNK1A1
InteractionKIF3C interactions

KIF3B FEZ2 TFIP11

1.52e-0426813int:KIF3C
InteractionPLEKHG1 interactions

FAM184A CEP135 NINL PRPH

1.53e-0467814int:PLEKHG1
InteractionPIBF1 interactions

FAM184A CEP135 NINL MCRS1 TFIP11 KIFC3

1.55e-04200816int:PIBF1
InteractionCOMTD1 interactions

EPRS1 CCNYL1 PPFIBP1 TFIP11 HEATR3 XPOT

1.55e-04200816int:COMTD1
InteractionCCDC61 interactions

FAM184A CEP135 SRPRA

1.71e-0427813int:CCDC61
InteractionIFTAP interactions

LRPPRC SMARCC2 GNPAT

1.71e-0427813int:IFTAP
InteractionTHAP8 interactions

SETDB1 NINL TFIP11

1.91e-0428813int:THAP8
InteractionPNKD interactions

LRPPRC PPFIBP1 TFIP11 RIPK4 HEATR3

1.92e-04132815int:PNKD
InteractionPDE6B interactions

DAAM2 DAAM1 CHN2

2.12e-0429813int:PDE6B
InteractionCBY2 interactions

CCDC146 ING5 NINL MCRS1 KIFC3

2.13e-04135815int:CBY2
InteractionATAD3B interactions

EPRS1 CLEC11A POLD1 NINL RIPK4 DKK3

2.18e-04213816int:ATAD3B
InteractionERVK3-1 interactions

CEP135 NINL

2.37e-046812int:ERVK3-1
InteractionCCDC187 interactions

TFIP11 FRYL KIFC3 HOMER3

2.49e-0476814int:CCDC187
InteractionKRT6C interactions

DES TFIP11 KIFC3 PRPH

2.49e-0476814int:KRT6C
InteractionFAM83B interactions

POTEB3 CLEC11A CEP135 EPB41L4A PRPH

2.53e-04140815int:FAM83B
InteractionGTF2E1 interactions

GTF2E1 SMARCC1 SMARCC2 TRIM29 EXOSC4

2.88e-04144815int:GTF2E1
InteractionCHAF1A interactions

SETDB1 HSPBAP1 CEP135 SMARCC1 SMARCC2 PRKDC HEATR3

3.15e-04322817int:CHAF1A
InteractionPIM1 interactions

PRKDC UTRN DDX6 DCP1A

3.18e-0481814int:PIM1
InteractionCCHCR1 interactions

CEP135 ING5 NINL MCRS1 TFIP11 KIFC3

3.22e-04229816int:CCHCR1
InteractionDUX1 interactions

DES CENPE

3.31e-047812int:DUX1
InteractionCCDC146 interactions

CCDC146 NINL TFIP11 KIFC3

3.34e-0482814int:CCDC146
InteractionPCM1 interactions

FAM184A CENPE CEP135 ING5 NINL MCRS1 TFIP11 DKK3

3.53e-04434818int:PCM1
InteractionKDM1A interactions

SETDB1 N4BP2 ATG2B SMARCC1 SMARCC2 MCRS1 TFIP11 KIFC3 UTRN ODAD3 HOMER3 DCP1A

3.62e-049418112int:KDM1A
InteractionTPTE2 interactions

LRPPRC TFIP11 PTK7 XPOT

3.66e-0484814int:TPTE2
InteractionTXLNA interactions

EPRS1 CCDC146 CEP135 NINL SMARCC2 TFIP11

3.78e-04236816int:TXLNA
InteractionPEX14 interactions

LRPPRC N4BP2 PRKAR2A SMARCC2 HOMER3 GNPAT

3.86e-04237816int:PEX14
InteractionKRT8 interactions

DES UACA N4BP2 NINL TFIP11 KIFC3 XPOT PRPH

3.93e-04441818int:KRT8
InteractionZBTB4 interactions

UACA CENPE HOMER3

4.06e-0436813int:ZBTB4
InteractionYWHAG interactions

UACA PPFIBP1 N4BP2 CBY1 NINL ING4 FRYL RIPK4 PRKDC UTRN SH3RF3 RASAL2 DDX6 DCP1A

4.16e-0412488114int:YWHAG
InteractionYWHAH interactions

UACA PPFIBP1 CBY1 CEP135 NINL FRYL RIPK4 UTRN SH3RF3 HOMER3 RASAL2 DDX6 DCP1A

4.27e-0411028113int:YWHAH
InteractionMED4 interactions

FAM184A CENPE CCDC146 CEP135 ATG2B MCRS1 KIFC3 UTRN

4.49e-04450818int:MED4
InteractionKRT6A interactions

DES CENPE TFIP11 KIFC3 PRPH

4.67e-04160815int:KRT6A
InteractionEIF4E2 interactions

CBY1 NINL SH3RF3 HOMER3 EXOSC4 RASAL2

4.70e-04246816int:EIF4E2
InteractionMAGEA6 interactions

LRPPRC CCDC146 MCRS1 SNAP47

4.76e-0490814int:MAGEA6
InteractionZBTB21 interactions

CLEC11A CBY1 SH3RF3 RASAL2 DCP1A

4.80e-04161815int:ZBTB21
InteractionOFD1 interactions

FAM184A CENPE CEP135 NINL PRKAR2A KIFC3 TRAK2

4.93e-04347817int:OFD1
InteractionCARD9 interactions

CEP135 MCRS1 TFIP11 KIFC3 TRIM29

5.37e-04165815int:CARD9
InteractionBRPF3 interactions

SETDB1 CFAP36 ING5 ING4 MCRS1

5.52e-04166815int:BRPF3
GeneFamilyIntermediate filaments Type III

DES PRPH

6.30e-055462610
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF3B CENPE KIFC3

2.17e-0446463622
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

SMARCC1 SMARCC2 MSANTD4

3.30e-0453463532
GeneFamilyAnkyrin repeat domain containing

UACA POTED RIPK4 ANKRD18B

3.29e-03242464403
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

EPRS1 LRPPRC N4BP2 SMARCC1 FRYL PRKDC UTRN

6.37e-08193817abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellfacs-Bladder-nan-3m|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT1 GLG1 CLEC11A SRPRA UTRN PTK7

1.57e-0619681644f5b1b474399c9316729155f2ea95a82ca66e30
ToppCellfacs-Bladder-nan-3m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT1 GLG1 CLEC11A SRPRA UTRN PTK7

1.57e-06196816c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

DES CLEC11A CBY1 DAAM2 DKK3 PTK7

1.76e-06200816a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell(08)_PNEC-(2)_48hpi|(08)_PNEC / shred by cell type and Timepoint

GTF2E1 LRRC45 COQ8A PPFIBP1 NINL

6.16e-06142815e95d34170f5053678e0dd9793e68d93c03b05822
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC146 CFAP36 CBY1 ODAD3 ITIH2

1.65e-05174815179a52d77899a929396b98d4ab2c270dd2ec708e
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC146 CFAP36 CBY1 ODAD3 ITIH2

1.65e-051748159165a1094d345328e58962f4b2a20334c3e93ead
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

RIPK4 EPB41L4A TRIM29 DNAH5 ANKRD18B

2.33e-051878158407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MYO7A PPFIBP1 NINL HOMER3 DKK3

2.52e-051908159ce301841ce9486701fa28eb2a9929e35d476878
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 CFAP36 CBY1 ODAD3

2.58e-05191815e8d56e9f43943e9cc4dce83f2c234f19c2dd487d
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 CFAP36 CBY1 ODAD3

2.58e-0519181552e8d7dfaf1ebb6df8bf3a1f4546af59faa67657
ToppCellPND07-Epithelial-Epithelial_Airway|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 TRIM29 DNAH5 ODAD3

2.58e-05191815b55500eb416f4f339031acad16b2737e5b891d8e
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 CFAP36 CBY1 ODAD3

2.58e-051918158688708c9183ebcb200596501dc30cc12073f151
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PPFIBP1 NINL DAAM1 HOMER3 DKK3

2.65e-05192815b016e229300c183e14c0e2bba494bf49c7899112
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PPFIBP1 NINL DAAM1 HOMER3 DKK3

2.65e-05192815ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 CFAP36 CBY1 ODAD3

2.65e-05192815a50a6279371b3be682e334082637b7ab76b9a6e5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

UACA DAAM2 DAAM1 SH3RF3 DKK3

2.85e-05195815803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

UACA DAAM2 DAAM1 SH3RF3 DKK3

2.85e-051958154f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CENPE RIPK4 TRIM29 EXOSC4 ANKRD18B

2.85e-051958155812b1615676f3b77eb4769216b98b360c417c0d
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

UACA PPFIBP1 EPB41L4A SH3RF3 RASAL2

2.92e-051968154ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell(5)_Fibroblasts-(5)_Fibroblast-B_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

UACA CLEC11A DAAM2 DKK3 PTK7

3.07e-05198815196257c4420ac801ed9fbb444f11718adb7560ae
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DES CLEC11A DAAM2 DKK3 PTK7

3.14e-0519981538cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

UACA CLEC11A DAAM2 DKK3 PTK7

3.22e-05200815082e718c1da3f4fdd33a001d15ad3ddb2be985c7
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DES CLEC11A DAAM2 DKK3 PTK7

3.22e-0520081509537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

UACA CLEC11A DAAM2 DKK3 PTK7

3.22e-05200815731e55070a7ff315091855bd88cda30e5a7e1a98
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|367C / Donor, Lineage, Cell class and subclass (all cells)

FAM184A TRAK2 HEATR3 DDX6

1.58e-0414981441f28138bde45d0b814e116837e5a32b5e80d54a
ToppCell356C-Lymphocytic-ILC-ILC-2|356C / Donor, Lineage, Cell class and subclass (all cells)

MYO7A HSPBAP1 ATG2B IQCJ-SCHIP1

1.83e-041558140fd66c623cb433ceaa893bc21ba2e3b394faaf70
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

DMGDH DES NGEF DCP1A

2.22e-041638141e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DES N4BP2 PRKDC EPM2AIP1

2.44e-0416781455c3c68af269fcf40f2b080ae4489523609ad388
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FAM184A UACA ING5 FRYL

2.55e-041698142833a8a7094e4d407eb923f2bc59b9b112c6bae4
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

UACA PPFIBP1 EPB41L4A SH3RF3

2.67e-04171814bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCell356C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MYO7A HSPBAP1 ATG2B IQCJ-SCHIP1

2.67e-041718143d26ef58fe5231373d7df9ac79d225546918cf82
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NGEF RIPK4 TRIM29 ANKRD18B

2.73e-04172814e9095c3dac66cf93d31f5f88364b565abacb1e2d
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C22orf23 DNAH5 ITIH2 PRPH

2.79e-04173814a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCellAdult-Epithelial-basal_cell-D231|Adult / Lineage, Cell type, age group and donor

C22orf23 WDR87 EPB41L4A TRIM29

2.85e-04174814a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRYL DAAM1 BSN XPOT

2.85e-04174814f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 ODAD3 ITIH2

2.98e-04176814d6d7e4e937d49a5c0d16322c8dd3bf9e97eb8732
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 ODAD3 ITIH2

2.98e-04176814c03d80df2550c0d2b0452326480d6bf21d20fdd2
ToppCell3'_v3-lymph-node_spleen-Mast-Mast_cell_lympho|lymph-node_spleen / Manually curated celltypes from each tissue

COQ8A RIPK4 TRAK2 EPB41L4A

3.04e-0417781453040dbeb18574a48e352e4bce252c7c3018762c
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

GOLGA8B EPB41L4A DNAH5 ANKRD18B

3.11e-04178814fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C22orf23 MYO7A CCDC146 DNAH5

3.11e-041788146178706db4a855d72abc156537604d575624df56
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C22orf23 MYO7A CCDC146 DNAH5

3.11e-04178814f02076ece0fa899e620971c887ad4da7f48684ed
ToppCellfacs-Marrow-KLS-24m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C22orf23 CENPE CLEC11A BSN

3.17e-041798145297f7459b40ca780a1983fecc1bb9c035c7677e
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPBAP1 NINL RIPK4 SH3RF3

3.17e-0417981488dbec952507d84b85b08165eec80df99ed1e736
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPBAP1 NINL RIPK4 SH3RF3

3.17e-04179814daf8189a22786171e2b629261cf720736aa4ebdb
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

RIPK4 EPB41L4A TRIM29 ANKRD18B

3.17e-04179814d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C22orf23 MYO7A CCDC146 ODAD3

3.24e-041808142b8447c3487b0f29e1d5ded980fe5a96dffd7a9e
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C22orf23 MYO7A CCDC146 ODAD3

3.24e-04180814babbdc9d3127c62c8db1ce33e0be61669e004893
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PPFIBP1 IQCJ-SCHIP1 DNAH5 ANKRD18B

3.38e-0418281414a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

C22orf23 EPB41L4A TRIM29 ANKRD18B

3.45e-0418381400a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PPFIBP1 NGEF EPB41L4A CHN2

3.45e-0418381401ad18f198195ce341bae01a1c8c253cc4607766
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLEC11A CBY1 ODAD3 PTK7

3.45e-04183814269afec240a756eec3bbae5f30ec784281af3433
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

3.52e-04184814797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

3.52e-0418481477d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DES CLEC11A DKK3 PTK7

3.60e-04185814355b03c7ea438681e11a2b872c798c9ea26e1486
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FAM184A TRAK2 HEATR3 DDX6

3.67e-0418681474c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DMGDH FAM184A NINL KIFC3

3.67e-041868141850583d23903d08226aeb0edb3e07b0994330e4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DMGDH FAM184A NINL KIFC3

3.67e-041868144dafc215c42e7949f932a3627359c107943b5d6b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP1 NINL GMDS KIFC3

3.67e-04186814b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellCiliated-cil-2|World / Class top

C22orf23 CCDC146 DNAH5 ODAD3

3.75e-04187814e2e58ba039b5355c03c3b448e750aa37b0ea6913
ToppCellP15-Epithelial-airway_epithelial_cell-club_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C22orf23 CCDC146 DNAH5 ODAD3

3.75e-04187814a70aaae32426e9ddb1cbfbd0e0db24ccc96b9f40
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

UACA DAAM2 SH3RF3 DKK3

3.75e-04187814bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

FAM184A TRAK2 HEATR3 DDX6

3.75e-04187814816d37a70f7ec382a268fe828b3dfe737a36a4bf
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PPFIBP1 NGEF IQCJ-SCHIP1 ANKRD18B

3.82e-0418881450c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCellCiliated|World / Class top

C22orf23 CCDC146 DNAH5 ODAD3

3.82e-04188814cc9178361360b5800f96516ed6a65089c144b1ce
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

C22orf23 CCDC146 CFAP36 DNAH5

3.82e-041888148f30535a32968a81a304315a49c0d90a77d36948
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

UACA PPFIBP1 DAAM1 SH3RF3

3.82e-04188814e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellP15-Epithelial-airway_epithelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C22orf23 CCDC146 DNAH5 ODAD3

3.82e-04188814e3e71c0f2e374330620cb4d27638953ffa9f5298
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRPPRC COQ8A CENPE GNPAT

3.90e-0418981445b9d00a4968fb22207d95228cdcf022afe1e50b
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

3.90e-04189814057d7a03fdbe779122b203619a6f947f49b84d28
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

3.90e-0418981402c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

3.90e-04189814164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

UACA PPFIBP1 SH3RF3 RASAL2

3.90e-04189814b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-lung_ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C22orf23 CCDC146 DNAH5 ODAD3

3.90e-041898141c28ad1263891d963e483b6847d8e89cc1b2d07e
ToppCellPND10-Epithelial-Epithelial_Airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

3.90e-04189814407d8a59969d83f014600aae1a55092283a13970
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRPPRC COQ8A CENPE GNPAT

3.90e-041898148382d331e01e83591ba9c8ea83edbf2436c18b17
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C22orf23 CCDC146 DNAH5 ODAD3

3.90e-0418981400b20c2ed7876486c8e42e3a5b13023f44987a34
ToppCellHSPCs-Ery_prog.|HSPCs / Lineage and Cell class

EPRS1 GALNT1 KIFC3 BSN

3.90e-0418981437d2c45debed1564a40a1085b8b310c50923b9e7
ToppCellPND01-Epithelial-Epithelial_Airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

3.90e-0418981438cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

PPFIBP1 GMDS EPB41L4A SH3RF3

3.90e-0418981475c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

PPFIBP1 GMDS EPB41L4A SH3RF3

3.90e-04189814c81787a8c662db5d7814c583dd64562857629e81
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

3.90e-041898149f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

3.90e-04189814a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

3.90e-04189814e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C22orf23 CCDC146 DNAH5 ODAD3

3.98e-0419081473ac7be02742ee6cb003600631f6a03eecbf2083
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP1 NGEF IQCJ-SCHIP1 KIFC3

3.98e-04190814989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

UACA PPFIBP1 DAAM1 RASAL2

3.98e-041908140e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

4.06e-04191814acd844b477a069b2dcf07b2998e1b5c87dc0eb94
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

4.06e-04191814bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

4.06e-041918146880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCell(04)_Pre-ciliated|World / shred by cell type and Timepoint

CFAP36 CBY1 CEP135 ODAD3

4.06e-0419181437cf121e6e80760c8519075b7845b9029958a988
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 CFAP36 ODAD3

4.06e-041918141e21de183a9c09cfb6aad3f9b948087fb6bad061
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP1 IQCJ-SCHIP1 KIFC3 EPB41L4A

4.06e-041918141cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

4.06e-0419181496483adb97c81208aa513782550acd8a08b63866
ToppCellE16.5-Epithelial-Epithelial_Airway|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 CFAP36 ODAD3

4.14e-04192814bb7eb51bc079acacde42d8e55ba06d03eba2ea28
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

4.14e-04192814b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCellPND03-Epithelial-Epithelial_Airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C22orf23 CCDC146 DNAH5 ODAD3

4.14e-041928142d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

UACA KIFC3 DKK3 PTK7

4.14e-0419281462904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NGEF RIPK4 TRIM29 ANKRD18B

4.22e-041938147c34abdcb8839b9fb25457a79af6c5e7b9714b21
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DES UACA DAAM2 DKK3

4.30e-041948148fae8061b350336299aa81f378e07deadbd55123
DrugPicrotoxinin [17617-45-7]; Down 200; 13.6uM; PC3; HT_HG-U133A

SETDB1 FAM184A PPFIBP1 ING4 HOMER3 PTK7 PRPH

5.69e-061958074260_DN
DrugDeferoxamine mesylate [138-14-7]; Down 200; 6uM; MCF7; HT_HG-U133A

GLG1 POLD1 CEP135 ATG2B PRKAR2A SRPRA DDX6

6.08e-061978073417_DN
Drugarachidonic acid sodium salt; Down 200; 10uM; MCF7; HG-U133A

CLEC11A ING4 KIFC3 CHN2 HOMER3 ITIH2 PRPH

6.71e-06200807604_DN
DrugDihydroergotamine tartrate [5989-77-5]; Down 200; 3uM; HL60; HG-U133A

EPRS1 COQ8A CLEC11A SMARCC1 EXOSC4 XPOT

4.03e-051798061398_DN
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A

KLF11 COQ8A CBY1 ING4 SRPRA UTRN

5.30e-051888061667_UP
DrugTropicamide [1508-75-4]; Down 200; 14uM; PC3; HT_HG-U133A

GLG1 CEP135 TFIP11 CHN2 ITIH2 DDX6

6.13e-051938064280_DN
DrugSolasodine [126-17-0]; Down 200; 9.6uM; PC3; HT_HG-U133A

SMARCC1 PRKAR2A SRPRA TRAK2 HOMER3 DDX6

6.13e-051938064305_DN
DrugSalsolinol hydrobromide [38221-21-5]; Down 200; 15.4uM; PC3; HT_HG-U133A

SETDB1 FAM184A ING4 HOMER3 RASAL2 DDX6

6.31e-051948064232_DN
DrugCaptopril [62571-86-2]; Down 200; 17.2uM; HL60; HG-U133A

EPRS1 SMARCC1 SRPRA PRKDC TRAK2 HOMER3

6.31e-051948061988_DN
DrugNaltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; PC3; HT_HG-U133A

FAM184A PRKAR2A KIFC3 TRIM29 UTRN HOMER3

6.67e-051968062047_UP
Drugsulindac sulfide; Down 200; 50uM; MCF7; HG-U133A

CENPE GLG1 TUBGCP2 UTRN ITIH2 PRPH

6.86e-05197806308_DN
DrugSalbutamol [18559-94-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A

FAM184A GLG1 CLEC11A RIPK4 DDX6 PRPH

6.86e-051978062306_DN
DrugDiloxanide furoate [3736-81-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A

GLG1 SMARCC1 TFIP11 TUBGCP2 RASAL2 PRPH

6.86e-051978065025_DN
DrugMedrysone [2668-66-8]; Down 200; 11.6uM; PC3; HT_HG-U133A

GLG1 PRKAR2A ING4 SRPRA TFIP11 EXOSC4

6.86e-051978064266_DN
DrugEucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; PC3; HT_HG-U133A

CEP135 PRKAR2A ING4 TFIP11 UTRN HOMER3

7.26e-051998064316_DN
DrugNimesulide [51803-78-2]; Up 200; 13uM; HL60; HG-U133A

GLG1 CBY1 SMARCC1 ING4 TRAK2 EXOSC4

7.26e-051998061428_UP
Diseaseprimary ciliary dyskinesia (implicated_via_orthology)

CBY1 DNAH5 ODAD3

1.61e-0519773DOID:9562 (implicated_via_orthology)
Diseasesquamous cell carcinoma (implicated_via_orthology)

ING5 ING4

2.01e-053772DOID:1749 (implicated_via_orthology)
Diseaseresponse to mepolizumab

NHLRC1 UTRN

6.69e-055772EFO_0008459
Diseaseinter-alpha-trypsin inhibitor heavy chain H1 measurement

PRKAR2A ITIH2

1.40e-047772EFO_0801705
Diseasemelanoma (implicated_via_orthology)

ING5 ING4

1.86e-048772DOID:1909 (implicated_via_orthology)
Diseaseopportunistic bacterial infectious disease (implicated_via_orthology)

SMARCC1 SMARCC2

2.39e-049772DOID:0050340 (implicated_via_orthology)
DiseaseCoffin-Siris syndrome (implicated_via_orthology)

SMARCC1 SMARCC2

2.39e-049772DOID:1925 (implicated_via_orthology)
Diseasehepatocellular carcinoma (implicated_via_orthology)

UACA ING5 ING4

2.89e-0449773DOID:684 (implicated_via_orthology)
Diseasemethadone dose measurement

NHLRC1 CHN2 UTRN

5.78e-0462773EFO_0007907
DiseaseKartagener syndrome (implicated_via_orthology)

DNAH5 ODAD3

5.99e-0414772DOID:0050144 (implicated_via_orthology)
DiseaseAutosomal recessive primary microcephaly

CENPE CEP135

6.90e-0415772cv:C3711387
Diseaseidiopathic scoliosis (implicated_via_orthology)

ODAD3 PTK7

7.88e-0416772DOID:0060250 (implicated_via_orthology)
Diseaselateral occipital cortex volume measurement

NHLRC1 UTRN

8.91e-0417772EFO_0010311
Diseaseotitis media (implicated_via_orthology)

CBY1 DNAH5

1.50e-0322772DOID:10754 (implicated_via_orthology)
Diseaseinterleukin 5 measurement

SETDB1 SH3RF3

2.43e-0328772EFO_0008185

Protein segments in the cluster

PeptideGeneStartEntry
RDDIMRLDDTVHVVI

DDX6

206

P26196
LKELEEMERHITLEK

AGBL3

581

Q8NEM8
VSDLEHEEMKILREV

CFAP36

146

Q96G28
TAESHLMEKELDELR

CBY1

106

Q9Y3M2
DERAMQAIEKLEEIH

ANKRD18B

836

A2A2Z9
HRIAKLMADVVEEET

DCP1A

116

Q9NPI6
VEDMNEMERHFLELL

CCNYL1

266

Q8N7R7
QEKAEELHRMEVESL

FAM184A

216

Q8NB25
AMHSILERIAAEEEE

ATG2B

856

Q96BY7
IDLLEEHKHEIERMA

DAAM2

726

Q86T65
EISQKLREMEDIDHR

C22orf23

191

Q9BZE7
MDARLHEDHLERVLE

EXOSC4

201

Q9NPD3
HLEKIMEVNELTDRE

KIAA0895

501

Q8NCT3
FDELVREMVHADVEL

GMDS

351

O60547
EAMKTILDDLRAEDH

ITIH2

331

P19823
LEEHREKVNATEEML

PPFIBP1

141

Q86W92
TEELRQAAEMEELHR

BSN

1106

Q9UPA5
ELEHQLRAMERSLEE

HOMER3

306

Q9NSC5
LEEELRQLKEEMARH

PRPH

361

P41219
READLLQESLEHIEM

NAA16

201

Q6N069
DLIELLARLTIHMDE

FRYL

576

O94915
RLMAVEEELKKDHAE

RASAL2

1056

Q9UJF2
EKVEKSELHLMDRDL

LRPPRC

291

P42704
LEDSESLRIKEVEHM

LRRC45

426

Q96CN5
DFLMEEKELVAHLRS

TUBGCP2

501

Q9BSJ2
EEIAMLRLELDETKH

POTEB3

531

A0JP26
MEGHKAEEEVLDVLR

KCTD18

1

Q6PI47
ADERLEAVHEVLMLL

CHN2

381

P52757
KAMSRLEEELRHQED

CEP135

951

Q66GS9
IDLLEEHKHELDRMA

DAAM1

741

Q9Y4D1
HMIEEIVLVDDASER

GALNT1

146

Q10472
EEDHLARVEEAITRM

HSPBAP1

276

Q96EW2
EKMVEDCEHRLLELQ

GLG1

536

Q92896
LIEDDEMEGISHKRR

HEATR3

321

Q7Z4Q2
EEVSEILDEMSHKLR

GNPAT

101

O15228
DIMEHLRELSEELRV

EPM2AIP1

386

Q7L775
EEEIRHLKDEMARHL

DES

371

P17661
EVKVMEDAHLDAILI

COQ8A

551

Q8NI60
EMVDKHIRRLDADLA

ING5

91

Q8WYH8
ELFESDLDRIMEHIK

DMGDH

336

Q9UI17
SKLKDMRDEVLEHEL

MCRS1

291

Q96EZ8
MRDEVLEHELMVADR

MCRS1

296

Q96EZ8
VLDAMFERIVKADEH

PRKAR2A

151

P13861
DIMDICESILERKRH

KLF11

16

O14901
MDLLEEKADLREHVE

GOLGA8B

421

A8MQT2
EELEEAIERIHKTLM

EPB41L4A

171

Q9HCS5
FREVEELMEDTQHKL

DKK3

51

Q9UBP4
EDLALMEEMEAEHRL

POLD1

36

P28340
ELTLEHMETERLELA

CENPE

1171

Q02224
ALHELMREAEISLLE

NHLRC1

11

Q6VVB1
ELMDIIIETELVHDA

DNAH5

4111

Q8TE73
EMVDKHIRRLDTDLA

ING4

91

Q9UNL4
DDEELREQLDMHSII

FEZ2

136

Q9UHY8
EEIAMLRLELDETKH

POTED

531

Q86YR6
DDNEEVMRALLIHEK

GTF2E1

316

P29083
ELRDLTQEMEVHAEK

UTRN

2121

P46939
IMDALDERAKVLHED

TRIM29

346

Q14134
EDFEKVILEDVAMLH

EPRS1

246

P07814
LMHRFEREDVDDIKV

SNAP47

291

Q5SQN1
DLEKHRDLLMVENER

KIFC3

131

Q9BVG8
MEAEVVRTKHELEAL

ODAD3

251

A5D8V7
AVSERFLLELEHRME

NGEF

326

Q8N5V2
DAMLVDIEDLTRHAE

IQCJ-SCHIP1

536

B3KU38
DDMETKLLHLEDVVR

NINL

1056

Q9Y2I6
LHVDDRERMELLEEA

RIPK4

56

P57078
LRHFEELETIMDREK

SMARCC1

911

Q92922
IKLRHFEELETIMDR

SMARCC2

901

Q8TAQ2
RHLDMEHERLQLEKE

MSANTD4

241

Q8NCY6
EELGISMEELRHFID

SETDB1

31

Q15047
KVLRDEEMHALAIAE

CCDC146

871

Q8IYE0
AQEEEREREALMLKH

CLEC11A

36

Q9Y240
DIDMVTHLLAERDRD

TRAK2

111

O60296
RAIVEDHSLVAEEKM

KIF3B

426

O15066
DELELHKGEMYRVLE

SH3RF3

481

Q8TEJ3
EDMESVLDKMRDHLI

SRPRA

336

P08240
VHDDVLELEMDELNR

PRKDC

2076

P78527
VEMEREHEKSLSEIR

UACA

651

Q9BZF9
LMAIDSELVDRDVVH

XPOT

146

O43592
IILEATLHLAEIEDM

PTK7

311

Q13308
ILLHEDRILAMEESE

WDR87

2016

Q6ZQQ6
LEKMTEVLDHEERVI

TFIP11

356

Q9UBB9
LHVDEALEHLMRVLE

N4BP2

1696

Q86UW6
IFLKDHHDMLLEVER

MYO7A

726

Q13402
HHDMLLEVERDKAIT

MYO7A

731

Q13402