Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglycosylceramide flippase activity

ATP10B ATP10D

2.18e-0431712GO:0140351
GeneOntologyMolecularFunctionthreonine-tRNA ligase activity

TARS3 TARS1

2.18e-0431712GO:0004829
GeneOntologyMolecularFunctionC-rich single-stranded DNA binding

PCBP3 PCBP2

2.18e-0431712GO:1990829
GeneOntologyMolecularFunctiontRNA dihydrouridine synthase activity

DUS1L DUS2

4.33e-0441712GO:0017150
GeneOntologyMolecularFunctionpyrroline-5-carboxylate reductase activity

PYCR1 PYCR3

4.33e-0441712GO:0004735
GeneOntologyMolecularFunctionRNA dihydrouridine synthase activity

DUS1L DUS2

4.33e-0441712GO:0106413
DomainARM-type_fold

USP34 SMG1 NCAPD3 CAND1 GBF1 COPB1 MROH2A APC TRRAP RIF1 RIC8B RPTOR CTNNBL1 AP1G2 DAAM2 GCN1

7.41e-0833916816IPR016024
DomainARM-like

SMG1 NCAPD3 CAND1 COPB1 MROH2A APC TRRAP RIF1 RIC8B RPTOR CTNNBL1 AP1G2 DAAM2 GCN1

1.60e-0727016814IPR011989
Domain-

NCAPD3 CAND1 COPB1 APC TRRAP RIF1 RIC8B RPTOR CTNNBL1 AP1G2 DAAM2 GCN1

8.19e-07222168121.25.10.10
DomainRibosomal_L10e_CS

RPL10L RPL10

8.04e-0521682IPR018255
DomainRibosomal_L10e

RPL10L RPL10

8.04e-0521682IPR001197
DomainRIBOSOMAL_L10E

RPL10L RPL10

8.04e-0521682PS01257
DomainFrizzled

FZD1 SMO FZD2

1.12e-04111683IPR000539
DomainFrizzled

FZD1 SMO FZD2

1.12e-04111683PF01534
DomainFrizzled

FZD1 SMO FZD2

1.12e-04111683SM01330
DomainThrRS_core

TARS3 TARS1

2.40e-0431682IPR033728
DomainThr-tRNA-ligase_IIa

TARS3 TARS1

2.40e-0431682IPR002320
Domain-

PYCR1 PYCR3

2.40e-04316821.10.3730.10
DomainP5CR_dimer

PYCR1 PYCR3

2.40e-0431682PF14748
DomainP5CR_dimer

PYCR1 PYCR3

2.40e-0431682IPR029036
DomainRibosomal_L10e/L16

RPL10L RPL10

2.40e-0431682IPR016180
Domain-

RPL10L RPL10

2.40e-04316823.90.1170.10
DomainGABAAb_rcpt

GABRB1 GABRB3

2.40e-0431682IPR002289
DomainRibosomal_L16

RPL10L RPL10

2.40e-0431682PF00252
DomainFrizzled/SFRP

FZD1 SMO FZD2

3.67e-04161683IPR015526
DomainHEAT_REPEAT

SMG1 NCAPD3 CAND1 MROH2A GCN1

4.19e-04701685PS50077
DomainP5CR

PYCR1 PYCR3

4.77e-0441682PS00521
DomainPyrroline-COOH_reductase

PYCR1 PYCR3

4.77e-0441682IPR000304
DomaintRNA_hU_synthase_CS

DUS1L DUS2

4.77e-0441682IPR018517
DomaintRNA_hU_synthase

DUS1L DUS2

4.77e-0441682IPR001269
DomainUPF0034

DUS1L DUS2

4.77e-0441682PS01136
DomainDus

DUS1L DUS2

4.77e-0441682PF01207
DomainFRI

FZD1 SMO FZD2

7.28e-04201683SM00063
DomainL_LDH

LDHA LDHC

7.90e-0451682PS00064
DomainL-lactate_DH

LDHA LDHC

7.90e-0451682IPR011304
DomainL-lactate_DH_AS

LDHA LDHC

7.90e-0451682IPR018177
Domain-

FZD1 SMO FZD2

8.44e-042116831.10.2000.10
DomainHEAT

NCAPD3 CAND1 RPTOR GCN1

9.03e-04481684PF02985
DomainTGS

TARS3 TARS1

1.18e-0361682IPR004095
DomainTGS

TARS3 TARS1

1.18e-0361682PF02824
DomainFAT

SMG1 TRRAP

1.18e-0361682PS51189
DomainFATC

SMG1 TRRAP

1.18e-0361682PS51190
DomainFATC_dom

SMG1 TRRAP

1.18e-0361682IPR003152
DomainPIK_FAT

SMG1 TRRAP

1.18e-0361682IPR014009
DomainFATC

SMG1 TRRAP

1.18e-0361682SM01343
DomainFrizzled_dom

FZD1 SMO FZD2

1.26e-03241683IPR020067
DomainFZ

FZD1 SMO FZD2

1.26e-03241683PS50038
DomainFz

FZD1 SMO FZD2

1.26e-03241683PF01392
DomainIQ_motif_EF-hand-BS

IQSEC3 MYO7A ADGB SCN4A MYO15A

1.32e-03901685IPR000048
DomainIQ

IQSEC3 MYO7A ADGB SCN4A MYO15A

1.52e-03931685PS50096
DomainProC_N

PYCR1 PYCR3

1.64e-0371682IPR028939
DomaintRNA_SAD

TARS3 TARS1

1.64e-0371682IPR012947
DomainTGS-like

TARS3 TARS1

1.64e-0371682IPR012676
DomaintRNA_SAD

TARS3 TARS1

1.64e-0371682SM00863
DomainF420_oxidored

PYCR1 PYCR3

1.64e-0371682PF03807
DomaintRNA_SAD

TARS3 TARS1

1.64e-0371682PF07973
DomainHEAT

NCAPD3 CAND1 RPTOR GCN1

1.84e-03581684IPR000357
DomainLactate/malate_DH_N

LDHA LDHC

2.17e-0381682IPR001236
DomainL-lactate/malate_DH

LDHA LDHC

2.17e-0381682IPR001557
DomainThr/Ala-tRNA-synth_IIc_edit

TARS3 TARS1

2.17e-0381682IPR018163
DomainLdh_1_N

LDHA LDHC

2.17e-0381682PF00056
Domain-

ATP7B ATP10B UBLCP1 ATP10D

2.64e-036416843.40.50.1000
Domain-

LDHA LDHC

2.78e-03916823.90.110.10
DomainLactate/malate_DH_C

LDHA LDHC

2.78e-0391682IPR022383
DomainLdh_1_C

LDHA LDHC

2.78e-0391682PF02866
DomainMYTH4

MYO7A MYO15A

2.78e-0391682PS51016
DomainMyTH4

MYO7A MYO15A

2.78e-0391682SM00139
DomainLactate_DH/Glyco_Ohase_4_C

LDHA LDHC

2.78e-0391682IPR015955
DomainMyTH4_dom

MYO7A MYO15A

2.78e-0391682IPR000857
DomainMyTH4

MYO7A MYO15A

2.78e-0391682PF00784
DomainHGTP_anticodon

TARS3 TARS1

2.78e-0391682PF03129
Domain-

ATP7B ATP10B ATP10D

2.93e-033216833.40.1110.10
Domain-

ATP7B ATP10B ATP10D

2.93e-033216832.70.150.10
DomainHydrolase_3

ATP10B ATP10D

3.45e-03101682PF08282
DomainATPase_P-typ_cyto_domN

ATP7B ATP10B ATP10D

3.79e-03351683IPR023299
DomainIQ

IQSEC3 MYO7A SCN4A MYO15A

3.84e-03711684PF00612
DomainATPase_P-typ_P_site

ATP7B ATP10B ATP10D

4.11e-03361683IPR018303
DomainP_typ_ATPase

ATP7B ATP10B ATP10D

4.11e-03361683IPR001757
DomainATPASE_E1_E2

ATP7B ATP10B ATP10D

4.11e-03361683PS00154
Domainaa-tRNA-synt_IIb

TARS3 TARS1

4.19e-03111682IPR002314
Domain-

TARS3 TARS1

4.19e-031116823.40.50.800
DomaintRNA-synt_2b

TARS3 TARS1

4.19e-03111682PF00587
DomainATPase_P-typ_transduc_dom_A

ATP7B ATP10B ATP10D

4.44e-03371683IPR008250
DomainE1-E2_ATPase

ATP7B ATP10B ATP10D

4.44e-03371683PF00122
DomainKH_1

PCBP3 PCBP1 PCBP2

4.79e-03381683PF00013
DomainC8

SSPOP MUC5AC

5.00e-03121682PF08742
DomainTIL

SSPOP MUC5AC

5.00e-03121682PF01826
Domain-

PCBP3 PCBP1 PCBP2

5.15e-033916833.30.1370.10
DomainKH

PCBP3 PCBP1 PCBP2

5.53e-03401683SM00322
DomainKH_dom

PCBP3 PCBP1 PCBP2

5.53e-03401683IPR004087
DomainHAD-like_dom

ATP7B ATP10B UBLCP1 ATP10D

5.62e-03791684IPR023214
DomainUnchr_dom_Cys-rich

SSPOP MUC5AC

5.88e-03131682IPR014853
DomainC8

SSPOP MUC5AC

5.88e-03131682SM00832
DomainIQ

MYO7A ADGB SCN4A MYO15A

6.14e-03811684SM00015
DomainKH_TYPE_1

PCBP3 PCBP1 PCBP2

6.35e-03421683PS50084
DomainTIL_dom

SSPOP MUC5AC

6.82e-03141682IPR002919
Domain-

TARS3 TARS1

6.82e-031416823.10.20.30
DomainP_typ_ATPase_c

ATP10B ATP10D

6.82e-03141682IPR032630
DomainP-type_ATPase_N

ATP10B ATP10D

6.82e-03141682IPR032631
DomainAnticodon-bd

TARS3 TARS1

6.82e-03141682IPR004154
DomainP-type_ATPase_IV

ATP10B ATP10D

6.82e-03141682IPR006539
DomainBeta-grasp_dom

TARS3 TARS1

6.82e-03141682IPR012675
DomainPhoLip_ATPase_C

ATP10B ATP10D

6.82e-03141682PF16212
DomainPhoLip_ATPase_N

ATP10B ATP10D

6.82e-03141682PF16209
DomainKH_dom_type_1

PCBP3 PCBP1 PCBP2

7.23e-03441683IPR004088
DomainClathrin/coatomer_adapt-like_N

COPB1 AP1G2

7.82e-03151682IPR002553
Pubmed

Defining the membrane proteome of NK cells.

RPL10L NCAPD3 CAND1 GBF1 MAN2A1 ATP7B GALNT1 COPB1 ERAP1 PIGK INPP5K PSMD3 CHD4 AGPS LDHA DHRS7B NCOR1 ESYT2 SLC44A1 GYG1 CTNNBL1 EXOC7 PCBP1 PCBP2 GCN1 HSPA14 RPL10 CKLF

4.84e-1211681722819946888
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

RAF1 NCAPD3 CAND1 COPB1 PIGK DNAJC16 PEX1 FAM91A1 KEAP1 DHRS7B AAR2 RIF1 ESYT2 BRCA2 RPTOR TBK1 PYCR1 EXOC7

1.54e-096061721836538041
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RAF1 USP34 HDAC5 L3MBTL2 APC CHD4 BRMS1L KEAP1 RB1CC1 NCOR1 BRCA2 TBK1 LRP1 GCN1 PYCR3

3.08e-094181721534709266
Pubmed

Network organization of the human autophagy system.

CAND1 GBF1 KRT85 KEAP1 AGPS RB1CC1 RIF1 ESYT2 GYG1 RPTOR TBK1 TAOK1 GCN1 TARS1

4.34e-084371721420562859
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

RPL10L ADCY10 USP34 CAND1 DNAJC16 FAM91A1 DHX57 PSMD3 CHD4 LDHA TRRAP DHRS7B AAR2 TSR1 WDR87 GYG1 CTNNBL1 PYCR1 PCBP1 PCBP2 HSPA14 PYCR3 TARS1 RPL10

5.00e-0813351722429229926
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

STXBP5L LAMA2 PRDM7 SSPOP RIF1 LRP1 MUC5AC

6.52e-0871172733541421
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

CAND1 GBF1 COPB1 DNAJC16 PSMD3 CHD4 TRIM33 RIF1 ESYT2 PYCR1 MAP2K2 PCBP1 PCBP2 GCN1 TARS1 RPL10

1.33e-076381721633239621
Pubmed

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.

NCAPD3 L3MBTL2 KEAP1 RIF1 BRCA2 PCBP1 PCBP2 GCN1

2.19e-07125172821654808
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

RPL10L USP34 MTG1 PCBP3 MAN2A1 GALNT1 COPB1 ERAP1 PIGK DNAJC16 NAB2 CHD4 AGPS EPB41L4A LDHA DHRS7B SPCS3 ESYT2 LRP1 PYCR1 TAOK1 POFUT2 PYCR3 OR2AG1

2.30e-0714511722430550785
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

RAF1 GBF1 COPB1 PIGK FAM91A1 DHX57 CHD4 KEAP1 AGPS LDHA DUS2 RIF1 SPCS3 TSR1 TBK1 CTNNBL1 PYCR1 TAOK1 PCBP1 PCBP2 GCN1 MUC5AC HSPA14

3.30e-0713711722336244648
Pubmed

A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.

NCAPD3 P4HA2 GBF1 INPP5K AGPS DHRS7B AAR2 SPCS3 ESYT2 TARS3 RPTOR LRP1 MAP2K2 POFUT2 HSPA14 PYCR3

3.50e-076861721628380382
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

USP34 CAND1 COPB1 DNAJC16 APC FAM91A1 CHD4 AGPS LDHA TRIM23 TRIM33 NCOR1 RIF1 SYTL4 GCN1 TARS1 RPL10

3.62e-077771721735844135
Pubmed

A novel set of nuclear localization signals determine distributions of the alphaCP RNA-binding proteins.

PCBP3 PCBP1 PCBP2

4.74e-074172314612387
Pubmed

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.

IKBKE RPTOR TBK1

4.74e-074172324562310
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

P4HA2 COL12A1 CAND1 MAN2A1 ERAP1 PIGK APC KEAP1 AGPS RB1CC1 LDHA TRRAP UBLCP1 NCOR1 SPCS3 TSR1 TBK1 C3 PCBP1 PCBP2 POFUT2 RPL10

5.07e-0712971722233545068
Pubmed

Each member of the poly-r(C)-binding protein 1 (PCBP) family exhibits iron chaperone activity toward ferritin.

PCBP3 PCBP1 PCBP2

1.18e-065172323640898
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

RAF1 NCAPD3 CAND1 GBF1 COPB1 PSMD3 KEAP1 LDHA DHRS7B AAR2 NCOR1 RIF1 SPCS3 ESYT2 RPTOR PYCR1 PCBP1 PCBP2 GCN1 TARS1 RPL10

1.20e-0612571722137317656
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

CAND1 COPB1 PSMD3 CHD4 LDHA TRRAP C3 PLCG2 PCBP1 PCBP2 GCN1

1.29e-063441721130333137
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

USP34 SMG1 NCAPD3 COPB1 DHX57 PSMD3 RGS11 LDHA AAR2 SLC6A6 TSR1 TENM1 CTNNBL1 LRP1 PYCR1 PCBP2 PYCR3 RPL10

1.74e-069711721833306668
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

COPB1 FAM91A1 DHX57 CHD4 LDHA TSR1 TBK1 PYCR1 C3 TAOK1 PCBP1 GCN1 PYCR3 RPL10

1.98e-066011721433658012
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 SMG1 GBF1 HDAC5 ERAP1 DNAJC16 NFASC ESYT2 GCN1

1.99e-06225172912168954
Pubmed

Identification of two novel mammalian genes establishes a subfamily of KH-domain RNA-binding proteins.

PCBP3 PCBP1 PCBP2

2.35e-066172310936052
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

NCAPD3 COPB1 PIGK PSMD3 CHD4 KEAP1 AGPS TRRAP TRIM33 SPCS3 CTNNBL1 PCYT2 GCN1 HSPA14 RPL10

2.51e-067041721529955894
Pubmed

Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function.

IKBKE RPTOR TBK1

4.10e-067172330683688
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

CAND1 COPB1 DHX57 PSMD3 RGS11 AGPS LDHA TFAP2C RIF1 ESYT2 TSR1 PCBP1 PCBP2 GCN1

5.13e-066531721433742100
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

CAND1 GBF1 L3MBTL2 PIGK DNAJC16 CHD4 AAR2 RIF1 ESYT2 EXOC7 PCBP1 PCBP2 GCN1 RPL10

5.49e-066571721436180527
Pubmed

Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.

CAND1 HDAC5 COPB1 PSMD3 LDHA NCOR1 PCBP2 GCN1 TARS1

6.07e-06258172921081666
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

NCAPD3 TRAF1 CAND1 GBF1 COPB1 PSMD3 CHD4 AGPS PRDM7 LDHA RIF1 RIC8B TSR1 RPTOR TBK1 CTNNBL1 PYCR1 PCBP1 GCN1 TARS1 RPL10

8.35e-0614251722130948266
Pubmed

A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.

APC FZD1 FZD2

9.77e-06917239707618
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

CAND1 CHD4 LDHA TRIM33 NCOR1 BRCA2 PCBP1 PCBP2 GCN1 RPL10

1.26e-053571721037059091
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

NCAPD3 COPB1 APC CHD4 KEAP1 LDHA ESYT2 TSR1 TBK1 PYCR1 PCBP1 PCBP2 GCN1 TARS1 RPL10

1.32e-058091721532129710
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

CAND1 L3MBTL2 COPB1 DHX57 PSMD3 CHD4 AGPS LDHA TRRAP AAR2 RIF1 RPTOR CTNNBL1 PYCR1 AP1G2 PLCG2 PCBP1 GCN1 PYCR3 TARS1

1.33e-0513531722029467282
Pubmed

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.

CAND1 CHD4 LDHA NCOR1 RIF1 PCBP1 PCBP2

1.34e-05156172737108203
Pubmed

The TRAF2-p62 axis promotes proliferation and survival of liver cancer by activating mTORC1 pathway.

TRAF1 RPTOR TBK1

1.39e-0510172337081115
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

RPL10L RAF1 CAND1 COPB1 BSPRY APC PSMD3 CHD4 NCOR1 TSR1 WDR87 TBK1 DOT1L MAP2K2 PCBP1 PCBP2 GCN1 TARS1 RPL10

1.46e-0512471721927684187
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

CAND1 GBF1 COPB1 ERAP1 NAB2 CHD4 KEAP1 AGPS LDHA UBLCP1 ESYT2 IGHA1 GYG1 CTNNBL1 LRP1 PYCR1 PCBP1 PCBP2 GCN1 RPL10

1.54e-0513671722032687490
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

COPB1 CHD4 AGPS DHRS7B TRIM33 ESYT2 PYCR1 MAP2K2 PCBP1 PCBP2 GCN1 PYCR3

1.56e-055341721235032548
Pubmed

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.

SMG1 TRRAP RPTOR

1.90e-0511172320427287
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

NCAPD3 CAND1 GALNT1 COPB1 DNAJC16 PEX1 DHRS7B AAR2 SPCS3 ESYT2 RPTOR TBK1 EXOC7 GCN1 HSPA14 TARS1

1.97e-059421721631073040
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

RAF1 SMG1 NCAPD3 DNAJC16 APC PEX1 FAM91A1 DHX57 TSR1 TBK1 EXOC7 CMTR2 PLXNB1

2.33e-056501721338777146
Pubmed

Inhibin B and anti-Müllerian hormone in spermatic vein of subfertile men with varicocele.

AMH INHBB

2.43e-052172221285453
Pubmed

Loss of threonyl-tRNA synthetase-like protein Tarsl2 has little impact on protein synthesis but affects mouse development.

TARS3 TARS1

2.43e-052172237059185
Pubmed

Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains.

PCBP1 PCBP2

2.43e-05217227607214
Pubmed

Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2.

RAF1 MAP2K2

2.43e-05217228393135
Pubmed

Type XII collagen contributes to diversities in human corneal and limbal extracellular matrices.

COL12A1 C3

2.43e-05217229344363
Pubmed

αCP Poly(C) binding proteins act as global regulators of alternative polyadenylation.

PCBP1 PCBP2

2.43e-052172223629627
Pubmed

Epileptic encephalopathy de novo GABRB mutations impair γ-aminobutyric acid type A receptor function.

GABRB1 GABRB3

2.43e-052172226950270
Pubmed

Investigation of MYO15A and MYO7A Mutations in Iranian Patients with Nonsyndromic Hearing Loss.

MYO7A MYO15A

2.43e-052172231997689
Pubmed

A human homologue of Drosophila kelch associates with myosin-VIIa in specialized adhesion junctions.

MYO7A KEAP1

2.43e-052172211921171
Pubmed

Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKε and Reveal Mechanisms for Selective Inhibition.

IKBKE TBK1

2.43e-052172230082428
Pubmed

Nuclear accumulation of cRel following C-terminal phosphorylation by TBK1/IKK epsilon.

IKBKE TBK1

2.43e-052172216888014
Pubmed

Lactate dehydrogenase C is required for the protein expression of a sperm-specific isoform of lactate dehydrogenase A.

LDHA LDHC

2.43e-052172230590713
Pubmed

Distinct poly(rC) binding protein KH domain determinants for poliovirus translation initiation and viral RNA replication.

PCBP1 PCBP2

2.43e-052172212414943
Pubmed

Splicing factor poly(rC)-binding protein 1 is a novel and distinctive tumor suppressor.

PCBP1 PCBP2

2.43e-052172230132844
Pubmed

Metabolism of activated complement component C3 is mediated by the low density lipoprotein receptor-related protein/alpha(2)-macroglobulin receptor.

LRP1 C3

2.43e-052172210608878
Pubmed

Cutting edge: Role of TANK-binding kinase 1 and inducible IkappaB kinase in IFN responses against viruses in innate immune cells.

IKBKE TBK1

2.43e-052172217056502
Pubmed

Inhibin B is lower and anti-Müllerian hormone is similar in serum of men with spinal cord injuries compared to controls.

AMH INHBB

2.43e-052172225581422
Pubmed

Complement 3 deficiency and oral prednisolone improve strength and prolong survival of laminin alpha2-deficient mice.

LAMA2 C3

2.43e-052172212044978
Pubmed

Functionally distinct effects of the C-terminal regions of IKKε and TBK1 on type I IFN production.

IKBKE TBK1

2.43e-052172224722368
Pubmed

Serum anti-Müllerian hormone is more strongly related to ovarian follicular status than serum inhibin B, estradiol, FSH and LH on day 3.

AMH INHBB

2.43e-052172212571168
Pubmed

Identification of two KH domain proteins in the alpha-globin mRNP stability complex.

PCBP1 PCBP2

2.43e-05217227556077
Pubmed

The non-canonical IκB kinases IKKε and TBK1 as potential targets for the development of novel therapeutic drugs.

IKBKE TBK1

2.43e-052172223157677
Pubmed

House dust mite-induced endoplasmic reticulum stress mediates MUC5AC hypersecretion via TBK1 in airway epithelium.

TBK1 MUC5AC

2.43e-052172236719141
Pubmed

Loss-of-function mutations in MYO15A and OTOF cause non-syndromic hearing loss in two Yemeni families.

OTOF MYO15A

2.43e-052172237189200
Pubmed

Dehydroepiandrosterone supplementation improves predictive markers for diminished ovarian reserve: serum AMH, inhibin B and antral follicle count.

AMH INHBB

2.43e-052172223664458
Pubmed

αCP binding to a cytosine-rich subset of polypyrimidine tracts drives a novel pathway of cassette exon splicing in the mammalian transcriptome.

PCBP1 PCBP2

2.43e-052172226896798
Pubmed

Inhibin B and anti-Müllerian hormone as markers of gonadal function after treatment for medulloblastoma or posterior fossa ependymoma during childhood.

AMH INHBB

2.43e-052172221168856
Pubmed

Identification of TBK1 and IKKε, the non-canonical IκB kinases, as crucial pro-survival factors in HTLV-1-transformed T lymphocytes.

IKBKE TBK1

2.43e-052172227123832
Pubmed

GABAA receptors involved in sleep and anaesthesia: β1- versus β3-containing assemblies.

GABRB1 GABRB3

2.43e-052172221735059
Pubmed

IKKε and TBK1 expression in gastric cancer.

IKBKE TBK1

2.43e-052172227145266
Pubmed

Inhibition of TBK1/IKKε Promotes Regeneration of Pancreatic β-cells.

IKBKE TBK1

2.43e-052172230349097
Pubmed

Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity.

IKBKE TBK1

2.43e-052172215367631
Pubmed

A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and editing activities.

TARS3 TARS1

2.43e-052172229579307
Pubmed

Poly(rC) binding protein 2 binds to stem-loop IV of the poliovirus RNA 5' noncoding region: identification by automated liquid chromatography-tandem mass spectrometry.

PCBP1 PCBP2

2.43e-05217228855318
Pubmed

IKKε and TBK1 in diffuse large B-cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF-κB and IL-10 signalling.

IKBKE TBK1

2.43e-052172232858764
Pubmed

Multiple modes for conferring surface expression of homomeric beta1 GABAA receptors.

GABRB1 GABRB3

2.43e-052172218650446
Pubmed

Increased IKKϵ protein stability ensures efficient type I interferon responses in conditions of TBK1 deficiency.

IKBKE TBK1

2.43e-052172236936901
Pubmed

Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functions.

IKBKE TBK1

2.43e-052172223096996
Pubmed

Mammary tumor induction and premature ovarian failure in ApcMin mice are not enhanced by Brca2 deficiency.

APC BRCA2

2.43e-052172211215675
Pubmed

The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection.

IKBKE TBK1

2.43e-052172215210742
Pubmed

Dose inhibin B or anti-Müllerian hormone relate to precocious puberty in girls? result of a systematic review and meta-analysis.

AMH INHBB

2.43e-052172237996919
Pubmed

Anti-mullerian hormone and inhibin B in the definition of ovarian aging and the menopause transition.

AMH INHBB

2.43e-052172218593767
Pubmed

Purified human erythrocyte pyrroline-5-carboxylate reductase. Preferential oxidation of NADPH.

PYCR1 PYCR3

2.43e-05217222722838
Pubmed

Human lactate dehydrogenase A (LDHA) rescues mouse Ldhc-null sperm function.

LDHA LDHC

2.43e-052172223467744
Pubmed

Cy3-ATP labeling of unfixed, permeabilized mouse hair cells.

MYO7A MYO15A

2.43e-052172234903829
Pubmed

Abundance of repetitive sequence elements in the mouse testis-specific lactate dehydrogenase-C gene.

LDHA LDHC

2.43e-052172214581519
Pubmed

A set of highly conserved RNA-binding proteins, alphaCP-1 and alphaCP-2, implicated in mRNA stabilization, are coexpressed from an intronless gene and its intron-containing paralog.

PCBP1 PCBP2

2.43e-052172210455157
Pubmed

Wnt/frizzled signalling modulates the migration and differentiation of immortalized cardiac fibroblasts.

FZD1 FZD2

2.43e-052172220189955
Pubmed

Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation.

IKBKE TBK1

2.43e-052172222619329
Pubmed

The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy.

IKBKE TBK1

2.43e-052172230504235
Pubmed

Herpesvirus-mediated stabilization of ICP0 expression neutralizes restriction by TRIM23.

TRIM23 TBK1

2.43e-052172234903664
Pubmed

Increased intrafollicular androgen levels affect human granulosa cell secretion of anti-Müllerian hormone and inhibin-B.

AMH INHBB

2.43e-052172217628551
Pubmed

Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated?

IKBKE TBK1

2.43e-052172218353649
Pubmed

Activation of the 41/43 kDa mitogen-activated protein kinase signaling pathway is required for hepatocyte growth factor-induced cell scattering.

RAF1 MAP2K2

2.43e-05217229671314
Pubmed

The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis.

TRIM33 TAL1

2.43e-052172215314655
Pubmed

Undetectable anti-Mullerian hormone and inhibin B do not preclude the presence of germ cell tumours in 45,X/46,XY or 46,XY gonadal dysgenesis.

AMH INHBB

2.43e-052172236905105
Pubmed

Crystal structure and mechanism of activation of TANK-binding kinase 1.

IKBKE TBK1

2.43e-052172223453971
Pubmed

Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma.

TBK1 DCLK2

2.43e-052172238211588
Pubmed

Antagonistic effects of cellular poly(C) binding proteins on vesicular stomatitis virus gene expression.

PCBP1 PCBP2

2.43e-052172221752917
Pubmed

Clericuzio-type poikiloderma with neutropenia in a patient from India.

USB1 MUC5AC

2.43e-052172233111394
InteractionCOL11A1 interactions

RAF1 COL12A1 TRRAP BRCA2 PYCR1

3.21e-06291625int:COL11A1
InteractionCLEC16A interactions

RAF1 NCAPD3 CAND1 COPB1 PIGK DNAJC16 PEX1 FAM91A1 KEAP1 DHRS7B AAR2 RIF1 ESYT2 BRCA2 RPTOR TBK1 PYCR1 EXOC7

3.28e-0662916218int:CLEC16A
InteractionKDM1A interactions

RAF1 USP34 HDAC5 APC CHD4 TDO2 BRMS1L KEAP1 RB1CC1 TRRAP TFAP2C NCOR1 BRCA2 SH3D19 TBK1 LRP1 AP1G2 EXOC7 TAL1 GCN1 PYCR3

2.22e-0594116221int:KDM1A
InteractionSNW1 interactions

RAF1 TRAF1 CAND1 USB1 COPB1 PSMD3 CHD4 TRIM23 NCOR1 RIF1 IGHA1 CTNNBL1 TAOK1 DOT1L EXOC7 MAP2K2 PCBP1 GCN1

3.33e-0574716218int:SNW1
InteractionSMC1A interactions

HDAC5 L3MBTL2 COPB1 PEX1 CHD4 RB1CC1 TRRAP RIF1 BRCA2 DOT1L MAP2K2 PCBP1 GCN1

3.46e-0541816213int:SMC1A
InteractionEEF1AKMT3 interactions

RAF1 USP34 NAB2 PEX1 FAM91A1 LDHA UCKL1 TBK1 AP1G2 MAP2K2 GCN1 HSPA14

3.99e-0536416212int:EEF1AKMT3
InteractionFNDC5 interactions

RPL10L USP34 MTG1 PCBP3 MAN2A1 GALNT1 COPB1 ERAP1 PIGK DNAJC16 NAB2 CHD4 AGPS EPB41L4A LDHA DHRS7B SPCS3 ESYT2 IGHA1 LRP1 PYCR1 C3 TAOK1 BPIFB2 MUC5AC POFUT2 PYCR3

4.44e-05147016227int:FNDC5
InteractionRACK1 interactions

GABRB3 RAF1 CAND1 DHX57 CHD4 LDHA TRRAP TRIM23 AAR2 TRIM33 TSR1 TENM1 DOT1L MAP2K2 PCBP1 PCBP2 RPL10

5.44e-0570416217int:RACK1
InteractionSTIP1 interactions

CAND1 GBF1 COPB1 DNAJC16 PSMD3 CHD4 AAR2 ADGB TRIM33 RIF1 ESYT2 TBK1 PYCR1 MAP2K2 PCBP1 TAL1 PCBP2 GCN1 HSPA14 TARS1 RPL10

5.85e-05100616221int:STIP1
InteractionADGB interactions

RAF1 TRRAP ADGB

5.87e-05101623int:ADGB
InteractionWHRN interactions

MYO7A KEAP1 TBK1 MYO15A

6.11e-05271624int:WHRN
InteractionZDHHC15 interactions

STXBP5L LAMA2 PRDM7 SSPOP RIF1 LRP1 MUC5AC

6.86e-051251627int:ZDHHC15
Cytoband5q21-q22

MAN2A1 APC

8.33e-05417225q21-q22
CytobandEnsembl 112 genes in cytogenetic band chr12q13

KRT85 NAB2 OR6C68 KRT87P OR6C2 LRP1 PCBP2 AMIGO2

2.11e-044231728chr12q13
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD1 SMO FZD2

3.99e-05111153286
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 STXBP5L MROH2A SSPOP PKHD1 TENM1 MYO15A CNTN2 EPHA5

4.35e-0818417292cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 STXBP5L MROH2A SSPOP PKHD1 TENM1 MYO15A CNTN2 EPHA5

4.35e-081841729ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 STXBP5L MROH2A SSPOP PKHD1 TENM1 MYO15A CNTN2 EPHA5

4.35e-0818417292b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellnormal_Lung-MAST_cells|normal_Lung / Location, Cell class and cell subclass

PHF20 SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 TAL1 RPL10 CKLF

7.48e-071891728f09e387dc0626536050cd537dda212471a7267c4
ToppCellnormal_Lung-MAST_cells-MAST|normal_Lung / Location, Cell class and cell subclass

PHF20 SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 TAL1 RPL10 CKLF

7.48e-071891728fd053209034fca6eaefe0e5ad024ac4548a100c9
ToppCellmedial-2-Hematologic-Basophil/Mast_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PHF20 BSPRY SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 RPL10 CKLF

9.11e-07194172854d33508ce35b3d214214e4efbbb62f358667105
ToppCellmedial-Hematologic-Basophil/Mast_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PHF20 BSPRY SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 RPL10 CKLF

9.11e-071941728a89a03d4adebb9f644c27e199bff267180d8ef18
ToppCellmedial-Hematologic-Basophil/Mast_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PHF20 BSPRY SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 RPL10 CKLF

9.11e-071941728ccfc142fe10b4ba16f3036f3f352983ee3e9c8ec
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY10 RGSL1 MOV10L1 PKHD1 TENM1 MYO15A EPHA5

1.56e-06145172796712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A NFASC ATP10B GPR101 KCNB2 BRCA2 SCN4A

3.01e-061601727f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCell3'-Distal_airway-Immune_Myeloid_mast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PHF20 SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 TAL1 CKLF

8.99e-06189172796566f84c796d5b2e31f64090555f2b258f0c9f2
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PHF20 SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 TAL1 CKLF

8.99e-061891727b59cc66f7bb9b72895b775fbcf1ec1dc08610969
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PHF20 SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 TAL1 CKLF

8.99e-0618917271893765b1e3b306f1e133101c28403070a70c3c8
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PHF20 SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 TAL1 CKLF

8.99e-06189172719b639bc6b35fe1d1079f60c8138aa946a95f3bf
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PHF20 SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 TAL1 CKLF

8.99e-061891727f3cb1a8ddf7a4a95fb1b6e8fe5aa63ef037ca7a6
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GABRB3 INHBB STXBP5L BSPRY KCNB2 HS3ST6 AMIGO2

9.96e-0619217274d3a1c267739b1479217144656986972fc86db43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC ATP10D LRP1 DAAM2

1.07e-051941727240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC ATP10D LRP1 DAAM2

1.07e-051941727ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC LRP1 DAAM2 C3

1.10e-0519517273c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCelldistal-Hematologic-Basophil/Mast_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PHF20 SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 CKLF EPHA5

1.10e-0519517274f83449fce3717518e2acbba1a4b3bea765c0bdb
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC ATP10D LRP1 DAAM2

1.10e-05195172744d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCelldistal-2-Hematologic-Basophil/Mast_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PHF20 SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 RPL10 CKLF

1.14e-051961727ad21706a281f0b105eb3979e3e47fe0cec6c527f
ToppCelldistal-1-Hematologic-Basophil/Mast_1|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BSPRY SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 RPL10 CKLF

1.18e-051971727e33752427eefeacbbc538e1b35f37194bdabfc40
ToppCell(5)_Fibroblasts-(5)_Fibroblast-D|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

AMH TPST1 P4HA2 IGHA1 LRP1 C3 PLCG2

1.22e-051981727fd14efd8e6c74a04bde985c08dc34217c0ef1bab
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Npnt_(Retrosplenial_areas,_layer_5,_Npnt+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

AMH NMUR1 BPIFB2 MYO15A

1.87e-05411724b1e70962de91a747ec718a3fad4247fd0cb7d9a8
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Npnt_(Retrosplenial_areas,_layer_5,_Npnt+)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

AMH NMUR1 BPIFB2 MYO15A

1.87e-0541172416dbb13baa47c4db80ddd83ac36aad6c43b5461a
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 MROH2A LAMA2 MOV10L1 PKHD1 EPHA5

3.73e-051601726c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 MROH2A LAMA2 MOV10L1 PKHD1 EPHA5

3.73e-05160172625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

GABRB3 AMH STXBP5L NFASC KCNB2 CNNM1

4.73e-051671726c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCellASK428-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

SLC44A1 PIK3R6 SIGLEC6 TENM1 TAL1 RPL10

4.89e-051681726c399fcb4d1d0be48026c2ecabc34a5935e7adf73
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6|TCGA-Liver / Sample_Type by Project: Shred V9

ABRA PCBP3 LAMA2 NFASC NMUR1 DCLK2

5.06e-051691726e992530776cab922d0360b275fb9cb8bd0017b06
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB1 PRICKLE1 TMEM54 DAAM2 ARHGAP28 FZD2

5.58e-051721726073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPST1 P4HA2 SLC44A1 GPR75 PYCR1 AMIGO2

5.95e-051741726cdfc50e5383c8670ce5109736aff36406f46c03d
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-1|TCGA-Liver / Sample_Type by Project: Shred V9

PRICKLE1 EPB41L4A ITGB4 FZD1 SLC6A6 PKHD1

6.74e-05178172651c59dabf2d7aef1b1964f6f766d5ec07ef90f5a
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A ITGB4 BPIFB2 TAL1 RPL10 AMIGO2

7.39e-051811726cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 LAMA2 NFASC RGS11 TDO2 LRP1

7.39e-051811726c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP10B TDO2 KCNB2 SLC6A6 CNNM1 PKHD1

7.39e-0518117266956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NWD1 ITGB4 TFAP2C SYTL4 DAAM2 PLXNB1

7.39e-0518117260c3f469bed108994ed696230e3c30343f7a301d3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 LAMA2 NFASC RGS11 TDO2 LRP1

7.39e-051811726c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB1 TRAF1 NWD1 FZD1 HS3ST6 AMIGO2

7.86e-05183172625c96df8ea0c7bbedbb7699ee84ad6234d19cba8
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TPST1 P4HA2 LAMA2 LRP1 PYCR1 FZD2

8.10e-05184172601257e5c12e38b849fd3d9496c43ded666249ba5
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Mast_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

BSPRY PIK3R6 SIGLEC6 CTNNBL1 TAL1 RPL10

8.10e-051841726bc394eaa441fcaffcc4ace062741bca1da229324
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 LAMA2 GPR75 TENM1 LRP1 C3

8.34e-0518517269faa35ceb89ccd2979072286f063687c9f846ce3
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

STXBP5L BSPRY NFASC RGS11 KCNB2 HS3ST6

8.59e-051861726c7983281a290201567b398e9ea6baddb96c692bb
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

COL12A1 LAMA2 NFASC EPB41L4A DAAM2 DCLK2

8.59e-051861726cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GABRB3 PCBP3 STXBP5L RGS11 KCNB2 AMIGO2

8.59e-051861726b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GABRB3 PCBP3 STXBP5L RGS11 KCNB2 AMIGO2

9.11e-051881726c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC LRP1 DAAM2

9.66e-0519017262306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC LRP1 DAAM2

9.66e-0519017261f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GABRB3 STXBP5L NFASC KCNB2 CNNM1 TENM1

9.66e-051901726b1095b2a7467c152d16e4f19a9515aeb61fc9e3d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC LRP1 DAAM2

9.94e-051911726a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GABRB3 INHBB STXBP5L KCNB2 HS3ST6 AMIGO2

9.94e-05191172619832ddd559a353e1618fe853d79e3edfec6dcda
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

COL12A1 LAMA2 NFASC EPB41L4A DAAM2 DCLK2

9.94e-05191172678c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC LRP1 DAAM2

1.02e-0419217269093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC LRP1 DAAM2

1.02e-0419217269ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC44A1 SH3D19 C3 SMO PLXNB1 RPL10

1.02e-0419217260dc1f46e40346ed0b286e53b106a812441575100
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

USP34 CAND1 MAN2A1 DNAJC16 TRIM33 TAOK1

1.05e-041931726abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GABRB3 INHBB STXBP5L BSPRY KCNB2 HS3ST6

1.05e-0419317268603d1a38955ad2529d04e4704467c73ea5bfbda
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPST1 COL12A1 LAMA2 LRP1 C3 EPHA5

1.08e-041941726e2db75f4de114631b8bda4e188f84446545538b7
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INHBB TMEM54 BSPRY APC AGPS HS3ST6

1.08e-041941726715e02e5f3250b1bfdc26b7dfd656ba4e705ea84
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_granulocytic-basophil|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 TAL1 CKLF

1.08e-041941726aca009b9f1f320c0a65ea16df6595d7ede0b1fda
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC LRP1 DAAM2

1.11e-041951726d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC LRP1 DAAM2

1.11e-041951726d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

TPST1 NAB2 FZD1 LRP1 DAAM2 FZD2

1.11e-04195172678978d85273e5463a7f43e4c121e647fa6aba42b
ToppCell11.5-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

GABRB3 INHBB KCNB2 CNNM1 HS3ST6 AMIGO2

1.11e-041951726eda6ebe52c48bd6a9044886e75f584f46c2556e7
ToppCelldistal-3-Hematologic-Basophil/Mast_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 RPL10 CKLF

1.11e-041951726009986b5b32a7df3bdbe6cc1adf48023060f454f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC LRP1 DAAM2

1.14e-041961726a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3R6 IGHA1 SIGLEC6 CTNNBL1 TAL1 CKLF

1.14e-041961726102bced15ba1f2f9aafdcf07e64195b8e1b0d87c
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3R6 IGHA1 SIGLEC6 CTNNBL1 TAL1 CKLF

1.14e-04196172657fd7b39611e30a68429dea1801476b0d44c6dc1
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3R6 IGHA1 SIGLEC6 CTNNBL1 TAL1 CKLF

1.14e-0419617264f007bff8ed7592c277d8397b054e1c799157912
ToppCelldistal-Hematologic-Basophil/Mast_1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 RPL10 CKLF

1.14e-0419617263df0f8fce94bd573f9f9dfeb06d5f68202627740
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 LAMA2 NFASC LRP1 DAAM2 DCLK2

1.14e-041961726fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3R6 IGHA1 SIGLEC6 CTNNBL1 TAL1 CKLF

1.14e-04196172655e562be096a510f6414811238e633accd18570e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 LAMA2 NFASC LRP1 DAAM2 DCLK2

1.14e-041961726802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC LRP1 DAAM2

1.14e-041961726ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC LRP1 DAAM2

1.14e-04196172630ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC LRP1 DAAM2

1.14e-0419617263e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 SLC44A1 SH3D19 C3 SMO RPL10

1.14e-0419617262029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PRICKLE1 LAMA2 NFASC LRP1 DAAM2

1.18e-0419717266d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO7A LAMA2 NFASC PKHD1 SCNN1D DAAM2

1.18e-0419717266806ec223e542f0475303698eb78c1cc527f5c6b
ToppCellfacs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 GALNT1 COPB1 RB1CC1 SH3D19 TAOK1

1.21e-0419817262f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCellBronchial_Brush-Epithelial-Club|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CYP2J2 LDHA PYCR1 C3 MUC5AC RPL10

1.21e-04198172661292a2b5aacb6080a679a31b70a211bdec59a3b
ToppCellfacs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 GALNT1 COPB1 RB1CC1 SH3D19 TAOK1

1.21e-041981726f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCellmedial-2-Epithelial-Mucous|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CYP2J2 BSPRY TFAP2C C3 BPIFB2 MUC5AC

1.24e-0419917264737250b7ffa7cc19eb6b057d35d78f13b1afe66
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPST1 P4HA2 COL12A1 TDO2 AGPS PYCR1

1.24e-04199172601ab0363558f215f9979e20fd5170d8fee149cea
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRICKLE1 SLC35C1 ITGB4 SYTL4 DAAM2 DCLK2

1.24e-041991726a13f4b8a039304e685464cc8879659824cad5a3e
ToppCellmedial-Epithelial-Mucous|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CYP2J2 BSPRY TFAP2C C3 BPIFB2 MUC5AC

1.24e-0419917264385963ab25b5378e7964b984028c25b27e5794e
ToppCellBronchial_Brush-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CYP2J2 LDHA PYCR1 C3 MUC5AC RPL10

1.24e-04199172653b87edccc89a3e8a6c5166472f9ef24fcba416c
ToppCellILEUM-inflamed-(8)_Activated_fibroblasts|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TPST1 P4HA2 COL12A1 TDO2 LRP1 C3

1.24e-041991726317f412996d463ddf2e6a52ff41d5d676c77f43f
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAN2A1 SLC35C1 VPS8 PKHD1 PLCG2 PLXNB1

1.24e-041991726174f6013af6eafa577f84205a62927f2b367fda3
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA2 TDO2 FZD1 TENM1 C3 CNTN2

1.24e-041991726e1f1950d6f840485e263b83dc81b98910be3ae7a
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPST1 P4HA2 COL12A1 TDO2 AGPS PYCR1

1.24e-04199172608bdcabc3fce787578a8eb66fc8412b0974fa6cc
ToppCelldistal-Epithelial-Mucous-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CYP2J2 BSPRY ATP10B C3 BPIFB2 MUC5AC

1.24e-0419917260af89ef40807fc4ad79ab82a2186ab6e866c6931
ToppCellmedial-Epithelial-Mucous-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CYP2J2 BSPRY TFAP2C C3 BPIFB2 MUC5AC

1.24e-04199172653198bcf5f2f012a3ed1600d95c0923d6976a099
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Interneuron|3m / Sample Type, Dataset, Time_group, and Cell type.

PCBP3 STXBP5L IL1RAPL2 MLN DCLK2 RPL10

1.28e-042001726a313b9a8bde1ea80a6eae183b76fba46b86558b4
ToppCellBronchus_Control_(B.)-Epithelial-TX-Club|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

SLC35C1 BSPRY PYCR1 C3 PLCG2 MUC5AC

1.28e-042001726292c63693eb7f435335a8cfba07aa35b72139393
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

COL12A1 LAMA2 TAS2R5 IL1RAPL2 LRP1 DAAM2

1.28e-042001726251fd2923f108cd2086961d897244b392c32ad54
ToppCell(70)_Mast|World / shred on Cell_type and subtype

SLC44A1 PIK3R6 SIGLEC6 CTNNBL1 TAL1 RPL10

1.39e-042031726b7af2130b4965661b5a50717a7f82d8d498f8d08
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Proliferative_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP10B SSPOP IL1RAPL2 CNTN2 RPL10

1.45e-0412917250dcce7cb95bb3593626ecb34ed9da58c7de4e016
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

UBL3 BSPRY ATP10B TDO2

1.47e-046917243da27f504e82277fa4a8fb67d60fc26dee0a414f
DrugMoxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; PC3; HT_HG-U133A

INHBB NAB2 PPCDC TFAP2C TRIM23 FZD1 SLC44A1 SIGLEC6 PCBP2 RPL10 AMIGO2

2.44e-07195169117255_UP
Drugmonastrol; Down 200; 20uM; MCF7; HG-U133A

RPL10L HDAC5 UBL3 ERAP1 PEX1 PPCDC ATP10B SLC6A6 DUS2 EXOC7

2.38e-0619816910605_DN
DrugAC1L24G8

LDHA LDHC C3

7.90e-0661693CID000066023
DrugRifabutin [72559-06-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A

MTG1 NAB2 KEAP1 ITGB4 TSR1 EXOC7 POFUT2 PLXNB1 RPL10

9.95e-0618416994349_DN
DrugEstradiol-17 beta [50-28-2]; Up 200; 14.6uM; PC3; HT_HG-U133A

AMH MYO7A ERAP1 APC BRCA2 GPR75 TAL1 MUC5AC RPL10

1.58e-0519516996718_UP
DrugChlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; HL60; HT_HG-U133A

TRAF1 USB1 ERAP1 APC DHX57 DUS2 SIGLEC6 TSPAN14 EXOC7

1.65e-0519616991864_DN
DrugNitrocaramiphen hydrochloride; Down 200; 10.8uM; MCF7; HT_HG-U133A

ERAP1 NAB2 TRIM23 FZD1 NCOR1 SIGLEC6 PLCG2 EXOC7 PYCR3

1.79e-0519816997464_DN
DrugVancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; MCF7; HT_HG-U133A

ERAP1 APC LAMA2 TDO2 ADGB RIF1 NMBR MYO15A TAL1

1.86e-0519916994423_UP
DrugPHA-00745360 [351320-33-7]; Down 200; 1uM; PC3; HT_HG-U133A

USB1 STXBP5L NAB2 LAMA2 CHD4 FZD1 SIGLEC6 LRP1 EXOC7

1.94e-0520016993827_DN
Drug1-bromo-2-chloroethane

TDO2 NKPD1 C3

2.19e-0581693CID000007849
DiseaseAdenocarcinoma of lung (disorder)

RAF1 APC KEAP1 LDHA TRIM33 DOT1L CMTR2 EPHA5

2.52e-052061688C0152013
Diseaseprogressive familial intrahepatic cholestasis (implicated_via_orthology)

ATP10B ATP10D

9.63e-0531682DOID:0070221 (implicated_via_orthology)
DiseaseT-cell acute lymphoblastic leukemia (implicated_via_orthology)

RPL10L RPL10

9.63e-0531682DOID:5603 (implicated_via_orthology)
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GABRB1 GABRB3 NCOR1 PLXNB1

1.76e-04491684DOID:0060037 (implicated_via_orthology)
DiseaseMedulloblastoma

L3MBTL2 APC BRCA2 SMO

1.90e-04501684C0025149
Diseaseamino acid metabolic disorder (implicated_via_orthology)

TARS3 TARS1

1.92e-0441682DOID:9252 (implicated_via_orthology)
Diseaseautistic disorder (implicated_via_orthology)

RPL10L RPL10

1.92e-0441682DOID:12849 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

RAF1 ATP7B INPP5K LAMA2 KEAP1 RB1CC1 UBLCP1 NCOR1 RIF1 BRCA2 OTOF IL1RAPL2 TENM1 NMBR HSPA14 PLXNB1

4.44e-04107416816C0006142
Diseasecontactin-2 measurement

NFASC CNTN2

4.76e-0461682EFO_0008100
Diseasespondyloepiphyseal dysplasia congenita (implicated_via_orthology)

RPL10L RPL10

4.76e-0461682DOID:14789 (implicated_via_orthology)
Diseasemelanoma

RAF1 MYO7A TRRAP CNNM1 BRCA2 TAS2R60 MAP2K2

5.71e-042481687C0025202
Diseasesyndromic X-linked intellectual disability Najm type (implicated_via_orthology)

RPL10L RPL10

6.64e-0471682DOID:0060807 (implicated_via_orthology)
DiseaseAutistic Disorder

GABRB1 GABRB3 APC CHD4 TDO2 TRRAP RPL10

7.71e-042611687C0004352
Diseasehair colour measurement

RAF1 TRAF1 INHBB MROH2A PRDM7 KRT87P FZD1 PKHD1 CTNNBL1 LRP1 BPIFB2

8.37e-0461516811EFO_0007822
Diseasestachydrine measurement

INHBB PKHD1

8.82e-0481682EFO_0021169
Diseasehypokalemic periodic paralysis (implicated_via_orthology)

SCN4A SCNN1D

8.82e-0481682DOID:14452 (implicated_via_orthology)
Diseaseglycosyl-N-palmitoyl-sphingosine (d18:1/16:0) measurement

GABRB1 ATP10D

1.13e-0391682EFO_0800476
Diseasemedulloblastoma (is_implicated_in)

APC BRCA2

1.41e-03101682DOID:0050902 (is_implicated_in)
DiseaseCutaneous Melanoma

RAF1 TRRAP MAP2K2

1.65e-03411683C0151779
DiseaseNoonan Syndrome 1

RAF1 MAP2K2

1.71e-03111682C4551602
DiseaseTurner Syndrome, Male

RAF1 MAP2K2

1.71e-03111682C0041409
DiseaseFemale Pseudo-Turner Syndrome

RAF1 MAP2K2

1.71e-03111682C1527404
DiseaseChildhood Medulloblastoma

L3MBTL2 APC BRCA2

1.89e-03431683C0278510
DiseaseMelanotic medulloblastoma

L3MBTL2 APC BRCA2

1.89e-03431683C1275668
DiseaseMedullomyoblastoma

L3MBTL2 APC BRCA2

1.89e-03431683C0205833
DiseaseDesmoplastic Medulloblastoma

L3MBTL2 APC BRCA2

1.89e-03431683C0751291
DiseaseAdult Medulloblastoma

L3MBTL2 APC BRCA2

1.89e-03431683C0278876
DiseaseNon-Small Cell Lung Carcinoma

RAF1 APC KEAP1 ITGB4 MAP2K2

2.04e-031561685C0007131
DiseaseAmelogenesis Imperfecta

PEX1 ITGB4

2.05e-03121682C0002452
Diseaseoncostatin-M measurement

PSMD3 C3

2.05e-03121682EFO_0010792
Diseasevon Willebrand factor measurement, coagulation factor measurement

VPS8 EPB41L4A

2.05e-03121682EFO_0004629, EFO_0004634
DiseaseMalignant neoplasm of kidney

RAF1 ATP7B BRCA2

2.16e-03451683C0740457
DiseaseBenign tumor of pancreas

APC BRCA2

2.41e-03131682C0347284
Diseasesensory peripheral neuropathy, response to platinum based chemotherapy

GABRB1 ATP7B

2.41e-03131682EFO_0004647, MONDO_0002321
Diseaserhinitis (biomarker_via_orthology)

C3 MUC5AC

2.41e-03131682DOID:4483 (biomarker_via_orthology)
Diseasepre-eclampsia (implicated_via_orthology)

CYP2J2 C3

2.41e-03131682DOID:10591 (implicated_via_orthology)
Diseasegallbladder cancer (is_implicated_in)

APC KEAP1

2.41e-03131682DOID:3121 (is_implicated_in)
DiseaseMajor Depressive Disorder

ATP7B HDAC5 TDO2 LDHA IKBKE LRP1

2.76e-032431686C1269683
Diseasemyeloid white cell count

USP34 TPST1 TRAF1 VPS8 PPCDC PSMD3 SLC44A1 SH3D19 C3 TSPAN14 DOT1L MAP2K2 PLXNB1

2.84e-0393716813EFO_0007988
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

MYO7A OTOF MYO15A

3.09e-03511683cv:CN043650
DiseaseHepatitis

ATP7B KEAP1

3.22e-03151682C0019158
Diseasemyopia (is_implicated_in)

P4HA2 LAMA2

3.67e-03161682DOID:11830 (is_implicated_in)
DiseaseUnipolar Depression

ATP7B HDAC5 TDO2 LDHA IKBKE LRP1

3.78e-032591686C0041696
DiseaseGlycogen storage disease

LDHA GYG1

4.14e-03171682cv:C0017919
Diseaseocular hypertension (biomarker_via_orthology)

C3 SMO

4.14e-03171682DOID:9282 (biomarker_via_orthology)
DiseaseNoonan-Like Syndrome With Loose Anagen Hair

RAF1 MAP2K2

5.17e-03191682C3501846
DiseasePancreatic carcinoma

APC BRCA2

5.17e-03191682C0235974
DiseaseNoonan syndrome-like disorder with loose anagen hair

RAF1 MAP2K2

5.17e-03191682C1843181
DiseaseCardio-facio-cutaneous syndrome

RAF1 MAP2K2

5.17e-03191682C1275081
DiseaseCostello syndrome (disorder)

RAF1 MAP2K2

5.17e-03191682C0587248
Diseasepain

IQSEC3 LAMA2 KCNB2 LRP1 MLN

5.40e-031961685EFO_0003843
Diseaseneuropsychological test

GABRB3 NCAPD3 FAM91A1 KCNB2 SLC6A6

5.51e-031971685EFO_0003926

Protein segments in the cluster

PeptideGeneStartEntry
GRASVHSMISRKVTI

TPST1

186

O60507
TDPLIHKIARIAMGV

BHLHB9

336

Q6PI77
VKSIQIHGTMRVILE

ESYT2

291

A0FGR8
LLHDQTVIRKGPISM

TFAP2C

186

Q92754
MRGSSIKIVRHIIKE

CTNNBL1

521

Q8WYA6
PKGTMILTNLTALHR

CYP2J2

396

P51589
LKFRMGITISPVSHR

CYP2J2

481

P51589
TKATVVRLPVGRHML

ADGB

736

Q8N7X0
MAVGEPLVHIRVTLL

ADAM20

1

O43506
TITHGVPRVMRVLLL

ATP7B

1031

P35670
RRLGVTLVGHQKKIM

EPHA5

1006

P54756
VSRLTRHQKLPEMGS

FAM220BP

146

B1ANY3
VLPVLSMKHTKDRVG

AAR2

161

Q9Y312
TAVHMIRKVPELSSV

AP1G2

161

O75843
HPLKLVVTRALMITA

CLDN16

71

Q9Y5I7
TVNHKLLPVGRTVMV

C3

151

P01024
LLVGFSTLRNIKMHI

CMTR2

581

Q8IYT2
RMILLAHEKLSVPVT

DUS1L

131

Q6P1R4
MSLRVHTLPTLLGAV

AMIGO2

1

Q86SJ2
MKLNTRPSTGLLRHI

DOT1L

96

Q8TEK3
IRVKIGLAAGHISML

ADCY10

141

Q96PN6
KRMSVVVRHPLTGEI

ATP10B

771

O94823
KLVRSHLQVMTLAIG

ATP10D

1041

Q9P241
EQMPRLLGHKTVTVL

NWD1

356

Q149M9
VTKVQHRPSGLIMAR

MAP2K2

86

P36507
VLRKTRHVNILLFMG

RAF1

396

P04049
MKNHTVIRTFILLGL

OR6C2

1

Q9NZP2
VKMRSQRLLVTVIPH

RGS11

36

O94810
TVSALRKMGVKLTPH

PYCR1

41

P32322
NLRRVHPVSTMIKGL

LDHA

266

P00338
HLGTAVSVMAKIPLL

RB1CC1

191

Q8TDY2
SRIHTSLIGCIKALM

DAAM2

171

Q86T65
TTIILVSRLEPKLHM

OR2G2

46

Q8NGZ5
NVTLTIRLLMHGKEV

PCBP1

11

Q15365
IDPSLGHMIVTLVAR

NMBR

296

P28336
LRLHESKVLQPATMV

MOV10L1

811

Q9BXT6
TCLVILRHKAMRTPT

NMUR1

81

Q9HB89
TRLFHSLMVLEKIIG

MAN2A1

586

Q16706
MKATVIRHGETLRRT

KRT85

321

P78386
LVGSRTLPVDFHIKM

L3MBTL2

301

Q969R5
AVSHVGIKLLRMVKG

MYO15A

2791

Q9UKN7
LVGMATKPLHVRRLQ

NAB2

86

Q15742
TLIEGKMTHPRAIVV

LRP1

641

Q07954
HAVPKAAMVTALRKL

INHBB

96

P09529
HLSDIMVKGLRITPF

FAM91A1

81

Q658Y4
IVHRDIKPGNIMRLV

IKBKE

131

Q14164
VSILRRVKHPNIIML

DCLK2

441

Q8N568
RLAILLKVRDMVSSH

C1orf109

91

Q9NX04
VRKRTIIALGHLVMS

CAND1

191

Q86VP6
PLITITVRGRNVHMK

ERAP1

531

Q9NZ08
QIIPMVTELIGRSHR

MTG1

121

Q9BT17
TTDLVGRMLLVTKAH

PCYT2

146

Q99447
GSTLMPVHVEREIRL

PLXNB1

921

O43157
HIRIRAKSQGMALSL

COPB1

926

P53618
VSLFRIRTIMKHDGT

FZD2

436

Q14332
VRLRPGHMNVVLILS

DNAJC16

616

Q9Y2G8
NLRRVHPVSTMVKGL

LDHC

266

P07864
MKATVIRHGETLRRT

KRT87P

136

A6NCN2
VKNRMIRLHPDGTVL

GABRB1

136

P18505
VKNRMIRLHPDGTVL

GABRB3

136

P28472
IIVRHMAAPLIGQLT

LAMA2

1286

P24043
EVHLSTGARTMRKIV

LAMA2

2596

P24043
RQSVVVLMGSLAKHL

GCN1

1316

Q92616
HVVLLLKMQVRGAAL

AMH

506

P03971
DRVVLTRKPVHGVMT

MUC5AC

4986

P98088
MTLTVKVLGARHLPK

PLCG2

1061

P16885
LSKMPISLAHGIIRS

GPR101

21

Q96P66
ILLTVLHMPSNEGRK

OR2AG1

221

Q9H205
GAVLMIVISDPRLHS

OR12D2

41

P58182
IVGMKTVLSVPHRRL

IQSEC3

856

Q9UPP2
HTIVDTVLMAPRSAK

ITGB4

881

P16144
SVKRLGIPDSHIVLM

PIGK

71

Q92643
MSLKTVAVIALHRLR

GPR75

131

O95800
VAVIALHRLRMVLGK

GPR75

136

O95800
SLMTRHSKVVSPVLI

EXOC7

156

Q9UPT5
GLNVTLTIRLLMHGK

PCBP3

41

P57721
LTIRLLMHGKEVGSI

PCBP3

46

P57721
RMQHITGLTVKTAEL

P4HA2

401

O15460
NVTLTIRLLMHGKEV

PCBP2

11

Q15366
EGRKIHVILARSTSM

PCTP

126

Q9UKL6
RGTIKLLSRAVMHAV

PRICKLE1

111

Q96MT3
KMGSIRHTISVRVKA

NFASC

321

O94856
VSLFRIRTIMKHDGT

FZD1

511

Q9UP38
LKRSRILHMALTGAS

SLC35C1

6

Q96A29
VPVHVIRMEQRSGLI

GALNT1

176

Q10472
HLTLMKRPELGVTLT

GYG1

71

P46976
MRILRILKLARHSTG

KCNB2

306

Q92953
KLDTIRTGLVGMLTH

BSPRY

156

Q5W0U4
EKMRHLITTGRPTKV

BRCA2

2391

P51587
VVPGNTRMVHLERLI

COL12A1

1981

Q99715
LLRKHQVVVISGMTG

DHX57

556

Q6P158
IKVSHVRMQGILLLV

INPP5K

86

Q9BT40
RLAGKPTHVNVSVVM

IGHA1

331

P01876
MGTATRRKPHLLLVA

CNTN2

1

Q02246
ILLLMKPSVLSRVSH

GBF1

1226

Q92538
FVAPMKHRRSALGIT

KEAP1

546

Q14145
TIRKAMATLGPHRVK

BRMS1L

226

Q5PSV4
LHRLISGVMTSKEII

SLC44A1

201

Q8WWI5
ALLPSMIKRRQGHIV

DHRS7B

176

Q6IAN0
MIKRRQGHIVAISSI

DHRS7B

181

Q6IAN0
HNKLILAPMVRVGTL

DUS2

11

Q9NX74
RVATSMRTVGKLPRH

HDAC5

476

Q9UQL6
HVLTRIGVMSLIRKK

CHD4

1491

Q14839
AIERIHKTLMGQIPS

EPB41L4A

176

Q9HCS5
MAVSVHSERKLLPLV

SCNN1D

281

P51172
GPIKTRLAISQSHLM

PEX1

1221

O43933
RIHAMSPDTKLIVVV

HS3ST6

166

Q96QI5
ILVMLRSHSGKARRK

OR4D1

221

Q15615
MALLIHLKTVSELRG

OTOF

1

Q9HC10
GMIIIIRLNSKLHTI

OR5D13

46

Q8NGL4
ILAVLTMKRDGSLHV

HSPA14

476

Q0VDF9
RVIEVLHGLQLKMSI

PHF20

751

Q9BVI0
RSKVRMAILHIIGQL

MROH2A

441

A6NES4
VARVHIGQVIMSIRT

RPL10L

126

Q96L21
VIIHRAILGSVERMI

TARS3

666

A2RTX5
PVIVHRAILGSVERM

TARS1

586

P26639
TGSEIIRMSLRHKPA

SYTL4

131

Q96C24
ICMILLITSLGRHRK

TAS2R60

211

P59551
APIIKEIASMRHVTT

RGSL1

716

A5PLK6
SLVNGKSPIRSLMHR

TRIM33

856

Q9UPN9
KSPIRSLMHRSARIG

TRIM33

861

Q9UPN9
RTVMNGALVKPTHII

SLC6A6

601

P31641
LSGLPQHIKSMVLRE

SLC6A16

446

Q9GZN6
RRGAIKVLIHALFSM

SCN4A

121

P35499
TKALAVRLEGTVVHM

SSPOP

1066

A2VEC9
TGRVHLSQMKIITPL

SH3D19

461

Q5HYK7
VVSRMHRVSVILKLL

TDO2

111

P48775
SVPIMGRRTKLQFLH

NKPD1

306

Q17RQ9
GAVRKIRSLMKTHRL

POFUT2

311

Q9Y2G5
VGSTVRNKLVRLMTH

RIC8B

401

Q9NVN3
VARVHIGQVIMSIRT

RPL10

126

P27635
VLGHISLPSMIRKIF

RIF1

841

Q5UIP0
MEITDGPHTKVVRRI

TAL1

176

P17542
SRLHNMLVSGEIKVI

IL1RAPL2

491

Q9NP60
ITTIKEMGRSIHEIP

NCOR1

1341

O75376
MLPGVSRLHTARVLV

PIK3R6

406

Q5UE93
TALMKPIVFALEHVR

SMG1

2011

Q96Q15
IRSGNILIHAAVMTK

PRDM7

466

Q9NQW5
SVPVRLHVSRIMLKN

SPCS3

36

P61009
KLSVRVMALTHRPNI

SIGLEC6

136

O43699
TMIHRDIKAGNILLT

TAOK1

146

Q7L7X3
RILLTHSTIPVGMIK

TENM1

1041

Q9UKZ4
MRKHTAITTFILLGL

OR6C68

1

A6NDL8
SVMRHSLLKGISAQI

VPS8

131

Q8N3P4
LMNGVSRRKVSRHIV

PKHD1

3946

P08F94
HRIAAQTLLGTAKML

PYCR3

206

Q53H96
SPMVRKELVVALSHL

RPTOR

656

Q8N122
RRPSLTIMHGKAITV

STXBP5L

336

Q9Y2K9
KVVGILMRARKHGLV

ABRA

346

Q8N0Z2
LKVRLGATPVAMLHT

BPIFB2

316

Q8N4F0
DLVVHIKMVTPRGII

AGPS

331

O00116
PRRLTSHLGTKVEMV

APC

301

P25054
SVKGHVKMLRLALTV

CKLF

16

Q9UBR5
RGSVMPSVIRAHAII

NCAPD3

911

P42695
MRVKISPQLLLATHR

CNNM1

601

Q9NRU3
APLMERKFHVLVGVT

PPCDC

11

Q96CD2
GKAFISLPSVRRHMI

ZNF564

371

Q8TBZ8
ISLKRIRKHMILHTG

ZNF564

431

Q8TBZ8
SLHSLILIMGIPRVK

TAS2R5

266

Q9NYW4
RMVIKRVVLSGHPFK

TSR1

691

Q2NL82
VLMKTGLVLVVLGHV

TMEM54

16

Q969K7
IRLRHNVIKTGVRMI

PSMD3

396

O43242
MVSRKAVAALLVVHV

MLN

1

P12872
IALLTRMGESVKHVT

SNX30

216

Q5VWJ9
GKTTVMHLVARETLP

UBL3

81

O95164
GVIRVHAPLLSKVSM

ARHGAP28

641

Q9P2N2
TGKRTHLSLFIVIMR

TRAF1

316

Q13077
HRMVILTILAIAPSV

TTLL2

346

Q9BWV7
PRLVRMKVFHLSLSQ

USB1

111

Q9BQ65
HVTKMVARRGAILPQ

SMO

621

Q99835
IVKPRLGTVMHRVIG

TMEM87B

311

Q96K49
MITVHTPRRGLIDVK

UBLCP1

216

Q8WVY7
VLKSTPQVRGMHTII

UCKL1

326

Q9NWZ5
TKVTRMHGIDPVVLV

TSPAN14

51

Q8NG11
VRTLLLIMEHGVKPH

USP34

2421

Q70CQ2
RVHIGPKMEIRVVTL

TRIM23

396

P36406
GKALRVHVTLTNTLM

TGM7

621

Q96PF1
IPITLAMEHVVLKRS

UHRF1BP1

1341

Q6BDS2
RIKTLSLMAEIGIHS

WDR87

971

Q6ZQQ6
TKVLRAVHSLLSRLM

TRRAP

2206

Q9Y4A5
IVHRDIKPGNIMRVI

TBK1

131

Q9UHD2
PKHTLSRVMVSKARG

MYO7A

1726

Q13402