Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainLAM_G_DOMAIN

GAS6 CNTNAP2

1.58e-0338292PS50025
DomainLaminin_G_2

GAS6 CNTNAP2

1.75e-0340292PF02210
DomainLamG

GAS6 CNTNAP2

2.11e-0344292SM00282
DomainLaminin_G

GAS6 CNTNAP2

3.65e-0358292IPR001791
Domain-

MYCBP2 CNTNAP2

5.71e-03732922.60.120.260
DomainEGF_1

FN1 GAS6 CNTNAP2

7.07e-03255293PS00022
DomainEGF-like_CS

FN1 GAS6 CNTNAP2

7.54e-03261293IPR013032
DomainGalactose-bd-like

MYCBP2 CNTNAP2

9.31e-0394292IPR008979
Domain-

GAS6 CNTNAP2

9.51e-03952922.60.120.200
Pubmed

The association of novel polymorphisms with stress fracture injury in Elite Athletes: Further insights from the SFEA cohort.

SOST VDR

7.19e-07230229129460
Pubmed

Host genetic background at CCR5 chemokine receptor and vitamin D receptor loci and human immunodeficiency virus (HIV) type 1 disease progression among HIV-seropositive injection drug users.

CCR5 VDR

7.19e-07230211679916
Pubmed

Expression of fibroblast growth factor 23, vitamin D receptor, and sclerostin in bone tissue from hypercalciuric stone formers.

SOST VDR

2.16e-06330224763863
Pubmed

Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites.

SOST VDR

2.16e-06330215514891
Pubmed

Association between vitamin D receptor, CCR5, TNF-alpha and TNF-beta gene polymorphisms and HBV infection and severity of liver disease.

CCR5 VDR

4.31e-06430216545485
Pubmed

Association of candidate susceptible loci with chronic infection with hepatitis B virus in a Chinese population.

CCR5 VDR

2.58e-05930220087947
Pubmed

Identification and comparative analysis of hepatitis C virus-host cell protein interactions.

FN1 MYCBP2

3.94e-051130224136289
Pubmed

Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment.

DEPDC5 CNTNAP2

1.09e-041830224939585
Pubmed

Requirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis.

SOST FN1

1.22e-041930224131868
Pubmed

Role of the Pbrm1 subunit and the PBAF complex in Schwann cell development.

SMARCC1 FN1

1.22e-041930235173232
Pubmed

Variation in the lymphotoxin-alpha/tumor necrosis factor locus modifies risk of erythema nodosum in sarcoidosis.

CCR5 VDR

1.22e-041930219225544
Pubmed

Mechanical load regulates bone growth via periosteal Osteocrin.

SOST FN1

1.64e-042230234260913
Pubmed

Novel interactors and a role for supervillin in early cytokinesis.

KIF14 PCNX3

2.68e-042830220309963
Pubmed

Polymorphisms in inflammatory genes and the risk of ischemic stroke and transient ischemic attack: results of a multilocus genotyping assay.

CCR5 VDR

3.74e-043330219028820
Pubmed

Identification of novel single nucleotide polymorphisms in inflammatory genes as risk factors associated with trachomatous trichiasis.

CCR5 VDR

3.74e-043330218974840
Pubmed

Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism.

CCR5 VDR

3.97e-043430220603037
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

SMARCC1 ZNF12 KIF14 TNFRSF8 UQCRFS1P1

4.30e-0475430535906200
Pubmed

Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.

SMARCC1 SSBP2 QARS1

4.99e-0418030330110629
Pubmed

Agrin has a pathological role in the progression of oral cancer.

KIF14 FN1 PCNX3

6.49e-0419730329872149
Pubmed

DNA sequence and analysis of human chromosome 8.

USP17L7 DLGAP2

7.92e-044830216421571
Cytoband3p21.31

SMARCC1 CCR5 QARS1

3.90e-051003033p21.31
Cytoband7p22.1

ZNF12 RBAK

4.38e-04473027p22.1
CytobandEnsembl 112 genes in cytogenetic band chr3p21

SMARCC1 CCR5 QARS1

1.14e-03316303chr3p21
CytobandEnsembl 112 genes in cytogenetic band chr7p22

ZNF12 RBAK

3.49e-03134302chr7p22
CoexpressionGERHOLD_ADIPOGENESIS_DN

FN1 VDR GAS6

4.41e-0562293M1576
CoexpressionGERHOLD_ADIPOGENESIS_DN

FN1 VDR GAS6

4.85e-0564293MM671
CoexpressionGSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_UP

DLGAP2 FN1 VDR GAS6

6.73e-05200294M4630
CoexpressionGSE17721_0.5H_VS_8H_CPG_BMDC_UP

SSBP2 BSCL2 FN1 VDR

6.73e-05200294M4126
CoexpressionGSE17721_0.5H_VS_24H_CPG_BMDC_UP

ST6GALNAC4 SSBP2 MYCBP2 VDR

6.73e-05200294M4128
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

ADCY10 SOST PTDSS1 CNTNAP2

6.83e-06184304ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DLGAP2 SSBP2 FN1 CNTNAP2

7.75e-061903047986586b7c82e91c71102cc8c4d7a689ae63ab4d
ComputationalNeighborhood of CDC16

SMARCC1 MYCBP2 PTDSS1

4.57e-0475223MORF_CDC16
ComputationalGenes in the cancer module 128.

CCR5 FN1 GAS6

9.69e-0497223MODULE_128
ComputationalGenes in the cancer module 79.

CCR5 FN1 GAS6

1.03e-0399223MODULE_79
ComputationalImmune response.

CCR5 FN1 GAS6

1.06e-03100223MODULE_170
Diseaseautism spectrum disorder (is_implicated_in)

VDR CNTNAP2

1.11e-0416292DOID:0060041 (is_implicated_in)
Diseasepeptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease

DEPDC5 CNTNAP2

2.54e-0424292EFO_0003948, EFO_0009923, MONDO_0004247
Diseaseamyotrophic lateral sclerosis (is_implicated_in)

UNC13A VDR

4.54e-0432292DOID:332 (is_implicated_in)
DiseaseBehcet's disease (is_implicated_in)

CCR5 VDR

5.76e-0436292DOID:13241 (is_implicated_in)
Diseasehepatitis B (is_implicated_in)

CCR5 VDR

6.08e-0437292DOID:2043 (is_implicated_in)
Diseasehuman immunodeficiency virus infectious disease (is_implicated_in)

CCR5 VDR

6.76e-0439292DOID:526 (is_implicated_in)
DiseaseNodular glomerulosclerosis

FN1 GAS6

7.47e-0441292C0017667
DiseaseDiabetic Nephropathy

FN1 GAS6

8.60e-0444292C0011881
Diseasegout

SMARCC1 VDR CNTNAP2

9.29e-04196293EFO_0004274
Diseaseunipolar depression, information processing speed, cognitive function measurement

ADCY10 DLGAP2

9.81e-0447292EFO_0003761, EFO_0004363, EFO_0008354

Protein segments in the cluster

PeptideGeneStartEntry
LDAHHKTYDPTYSDF

VDR

136

P11473
YHSCHSSVSYHKDSP

UNC13A

301

Q9UPW8
PRMHYSSHYDTRDDC

DLGAP2

161

Q9P1A6
TKCTTFMHYYPSGEH

ADCY10

231

Q96PN6
KEGLHYTCSSHFPYS

CCR5

171

P51681
SSHPACAKVEYAYSD

MLX

61

Q9UH92
IHYTYSLCPSHSDSE

DEPDC5

886

O75140
DECHPHYASQTTVYE

KIF14

411

Q15058
DAHTVVSHPDKYCFY

PCNX3

1161

Q9H6A9
PHEATCYDDGKTYHV

FN1

2381

P02751
DEAAYKHSDITAHSC

GAS6

656

Q14393
DYHSPYTMDCHRAKA

MS4A6E

101

Q96DS6
HNSIYEPSCEAYKHL

CNTNAP2

591

Q9UHC6
SHLSPVHFYYRTDCD

BSCL2

61

Q96G97
CDHSVIVSASYSDPY

OR5D13

181

Q8NGL4
HTYSLESLCHCPFYE

MIGA1

341

Q8NAN2
PTYDYTHCLCDSIEH

QARS1

436

P47897
TCEHSSEAKAFHDYS

SSBP2

81

P81877
TSSHYAVIESEHPYK

MYCBP2

2016

O75592
PHHPFETKDVSEYSC

SOST

66

Q9BQB4
KASHHIYPYSSSQDD

SMARCC1

201

Q92922
DSYCREKSHPSVPYH

ST6GALNAC4

236

Q9H4F1
KFTSTCHFTYPASHD

TEX37

101

Q96LM6
EHYRSHSEEKPYGCS

RBAK

556

Q9NYW8
EDTCHGNPSHYYDKA

TNFRSF8

26

P28908
KYLHCHGVSDTFDPY

USP17L7

206

P0C7H9
CYSHTDIKVPDFSEY

UQCRFS1P1

86

P0C7P4
THATDKYSDYHPCTE

ZNF782

331

Q6ZMW2
HYRTHSGEKPYECTE

ZNF12

651

P17014
AEHYGHREKTYSECE

PTDSS1

406

P48651
TTVHCTHEAVYPLYT

JKAMP

141

Q9P055