Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionkainate selective glutamate receptor activity

GRIK1 GRIK2 GRIK3

6.85e-096153GO:0015277
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIK1 GRIK2 GRIK3

2.32e-0717153GO:0004970
GeneOntologyMolecularFunctionligand-gated sodium channel activity

GRIK1 GRIK2 GRIK3

2.78e-0718153GO:0015280
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIK1 GRIK2 GRIK3

6.88e-0724153GO:0099507
GeneOntologyMolecularFunctionglutamate receptor activity

GRIK1 GRIK2 GRIK3

9.92e-0727153GO:0008066
GeneOntologyMolecularFunctionsodium channel activity

GRIK1 GRIK2 GRIK3

7.41e-0652153GO:0005272
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRIK1 GRIK2 GRIK3

9.79e-0657153GO:1904315
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

GRIK1 GRIK2

1.10e-057152GO:0005234
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRIK1 GRIK2 GRIK3

1.14e-0560153GO:0099529
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GRIK1 GRIK2 GRIK3

1.46e-0565153GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GRIK1 GRIK2 GRIK3

1.46e-0565153GO:0022824
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GRIK1 GRIK2 GRIK3

2.24e-0575153GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GRIK1 GRIK2 GRIK3

2.43e-0577153GO:0005230
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GRIK1 GRIK2 GRIK3

5.31e-05100153GO:0030594
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

GRIK1 GRIK2 GRIK3

6.14e-05105153GO:0015171
GeneOntologyMolecularFunctionpotassium channel activity

GRIK1 GRIK2 GRIK3

1.11e-04128153GO:0005267
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

GRIK1 GRIK2 GRIK3

1.44e-04140153GO:0099094
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

GRIK1 GRIK2 GRIK3

2.43e-04167153GO:0015079
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

GRIK1 GRIK2 GRIK3

2.60e-04171153GO:0015081
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GRIK1 GRIK2 GRIK3

3.71e-04193153GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

GRIK1 GRIK2 GRIK3

3.94e-04197153GO:0022834
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

GRIK1 GRIK2 GRIK3

4.56e-04207153GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

GRIK1 GRIK2 GRIK3

4.62e-04208153GO:0005342
GeneOntologyMolecularFunctionexcitatory extracellular ligand-gated monoatomic ion channel activity

GRIK1 GRIK2

4.67e-0443152GO:0005231
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

GRIK1 GRIK2 GRIK3

1.25e-03293153GO:0008514
GeneOntologyMolecularFunctiongated channel activity

GRIK1 GRIK2 GRIK3

1.82e-03334153GO:0022836
GeneOntologyMolecularFunctionmonoatomic cation channel activity

GRIK1 GRIK2 GRIK3

1.96e-03343153GO:0005261
GeneOntologyMolecularFunctionscaffold protein binding

GRIK1 GRIK2

2.17e-0393152GO:0097110
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GRIK1 GRIK2 GRIK3

4.47e-03459153GO:0005216
GeneOntologyMolecularFunctionSNARE binding

GRIK1 GRIK2

4.56e-03136152GO:0000149
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

GRIK1 GRIK2 GRIK3

4.63e-03465153GO:0046873
GeneOntologyMolecularFunctionchannel activity

GRIK1 GRIK2 GRIK3

6.50e-03525153GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GRIK1 GRIK2 GRIK3

6.53e-03526153GO:0022803
GeneOntologyMolecularFunctionaminoacyltransferase activity

PELI1 TRIM71 TGM7

6.74e-03532153GO:0016755
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

GRIK1 GRIK2 GRIK3

1.06e-02627153GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

GRIK1 GRIK2 GRIK3

1.24e-02664153GO:0008324
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

GRIK1 GRIK2 GRIK3

1.76e-02758153GO:0015318
GeneOntologyMolecularFunctionacyltransferase activity

PELI1 TRIM71 TGM7

1.87e-02775153GO:0016746
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

GRIK1 GRIK2 GRIK3

1.99e-02793153GO:0015075
GeneOntologyBiologicalProcessnegative regulation of synaptic transmission, glutamatergic

GRIK1 GRIK2 GRIK3

8.86e-0813153GO:0051967
GeneOntologyBiologicalProcessionotropic glutamate receptor signaling pathway

GRIK1 GRIK2 GRIK3

9.01e-0727153GO:0035235
GeneOntologyBiologicalProcessligand-gated ion channel signaling pathway

GRIK1 GRIK2 GRIK3

3.02e-0640153GO:1990806
GeneOntologyBiologicalProcessglutamate receptor signaling pathway

GRIK1 GRIK2 GRIK3

9.87e-0659153GO:0007215
GeneOntologyBiologicalProcessnegative regulation of synaptic transmission

GRIK1 GRIK2 GRIK3

2.47e-0580153GO:0050805
GeneOntologyBiologicalProcessregulation of synaptic transmission, glutamatergic

GRIK1 GRIK2 GRIK3

3.76e-0592153GO:0051966
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

GRIK1 GRIK2 GRIK3

1.10e-04132153GO:0035249
GeneOntologyBiologicalProcessregulation of short-term neuronal synaptic plasticity

GRIK1 GRIK2

1.13e-0422152GO:0048172
GeneOntologyBiologicalProcessinhibitory postsynaptic potential

GRIK1 GRIK2

1.71e-0427152GO:0060080
GeneOntologyBiologicalProcessregulation of presynaptic membrane potential

GRIK2 GRIK3

2.42e-0432152GO:0099505
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

GRIK1 GRIK2 GRIK3

2.75e-04180153GO:0060078
GeneOntologyBiologicalProcessregulation of long-term neuronal synaptic plasticity

GRIK1 GRIK2

3.79e-0440152GO:0048169
GeneOntologyBiologicalProcessmodulation of excitatory postsynaptic potential

GRIK1 GRIK2

1.00e-0365152GO:0098815
GeneOntologyBiologicalProcesspresynaptic modulation of chemical synaptic transmission

GRIK1 GRIK2

1.06e-0367152GO:0099171
GeneOntologyBiologicalProcessregulation of neuronal synaptic plasticity

GRIK1 GRIK2

1.62e-0383152GO:0048168
GeneOntologyCellularComponentkainate selective glutamate receptor complex

GRIK1 GRIK2 GRIK3

5.97e-096153GO:0032983
GeneOntologyCellularComponentsodium channel complex

GRIK1 GRIK2 GRIK3

1.08e-0629153GO:0034706
GeneOntologyCellularComponentionotropic glutamate receptor complex

GRIK1 GRIK2 GRIK3

4.17e-0645153GO:0008328
GeneOntologyCellularComponentneurotransmitter receptor complex

GRIK1 GRIK2 GRIK3

5.74e-0650153GO:0098878
GeneOntologyCellularComponentpresynaptic membrane

GRIK1 GRIK2 GRIK3 GPC4

3.67e-05277154GO:0042734
GeneOntologyCellularComponentterminal bouton

GRIK1 GRIK2 GRIK3

4.10e-0596153GO:0043195
GeneOntologyCellularComponentpotassium channel complex

GRIK1 GRIK2 GRIK3

5.21e-05104153GO:0034705
GeneOntologyCellularComponentpostsynaptic density membrane

GRIK1 GRIK2 GRIK3

1.77e-04157153GO:0098839
GeneOntologyCellularComponentdendrite cytoplasm

GRIK2 GRIK3

3.51e-0439152GO:0032839
GeneOntologyCellularComponentpostsynaptic specialization membrane

GRIK1 GRIK2 GRIK3

3.66e-04201153GO:0099634
GeneOntologyCellularComponentaxon terminus

GRIK1 GRIK2 GRIK3

4.16e-04210153GO:0043679
GeneOntologyCellularComponentcollagen-containing extracellular matrix

COL6A3 ITLN2 FGL1 GPC4

4.46e-04530154GO:0062023
GeneOntologyCellularComponentneuron projection terminus

GRIK1 GRIK2 GRIK3

5.63e-04233153GO:0044306
GeneOntologyCellularComponentcation channel complex

GRIK1 GRIK2 GRIK3

5.78e-04235153GO:0034703
GeneOntologyCellularComponentreceptor complex

GRIK1 GRIK2 GRIK3 ITLN2

6.31e-04581154GO:0043235
GeneOntologyCellularComponentsynaptic membrane

GRIK1 GRIK2 GRIK3 GPC4

6.40e-04583154GO:0097060
GeneOntologyCellularComponentextracellular matrix

COL6A3 ITLN2 FGL1 GPC4

9.95e-04656154GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL6A3 ITLN2 FGL1 GPC4

1.01e-03658154GO:0030312
GeneOntologyCellularComponentplasma membrane signaling receptor complex

GRIK1 GRIK2 GRIK3

1.82e-03350153GO:0098802
GeneOntologyCellularComponentglutamatergic synapse

GRIK1 GRIK2 GRIK3 GPC4

2.24e-03817154GO:0098978
GeneOntologyCellularComponentmonoatomic ion channel complex

GRIK1 GRIK2 GRIK3

2.27e-03378153GO:0034702
GeneOntologyCellularComponentP-body

TNRC6B TRIM71

2.38e-03102152GO:0000932
GeneOntologyCellularComponentneuron projection cytoplasm

GRIK2 GRIK3

2.76e-03110152GO:0120111
GeneOntologyCellularComponentpostsynaptic membrane

GRIK1 GRIK2 GRIK3

2.76e-03405153GO:0045211
GeneOntologyCellularComponentpresynapse

GRIK1 GRIK2 GRIK3 GPC4

3.01e-03886154GO:0098793
GeneOntologyCellularComponentaxon

GRIK1 GRIK2 GRIK3 POTEI

3.07e-03891154GO:0030424
GeneOntologyCellularComponentdistal axon

GRIK1 GRIK2 GRIK3

3.38e-03435153GO:0150034
GeneOntologyCellularComponentpostsynaptic density

GRIK1 GRIK2 GRIK3

3.74e-03451153GO:0014069
GeneOntologyCellularComponentasymmetric synapse

GRIK1 GRIK2 GRIK3

4.38e-03477153GO:0032279
GeneOntologyCellularComponentpostsynaptic specialization

GRIK1 GRIK2 GRIK3

5.08e-03503153GO:0099572
GeneOntologyCellularComponentneuron to neuron synapse

GRIK1 GRIK2 GRIK3

5.66e-03523153GO:0098984
GeneOntologyCellularComponenttransmembrane transporter complex

GRIK1 GRIK2 GRIK3

5.66e-03523153GO:1902495
GeneOntologyCellularComponenttransporter complex

GRIK1 GRIK2 GRIK3

6.51e-03550153GO:1990351
GeneOntologyCellularComponentperikaryon

GRIK2 GRIK3

1.09e-02223152GO:0043204
GeneOntologyCellularComponentcytoplasmic ribonucleoprotein granule

TNRC6B TRIM71

1.55e-02269152GO:0036464
GeneOntologyCellularComponentplasma membrane protein complex

GRIK1 GRIK2 GRIK3

1.71e-02785153GO:0098797
GeneOntologyCellularComponentribonucleoprotein granule

TNRC6B TRIM71

1.75e-02287152GO:0035770
GeneOntologyCellularComponentneuronal cell body

GRIK1 GRIK2 GRIK3

2.02e-02835153GO:0043025
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

GRIK2 GRIK3

2.11e-02317152GO:0032838
GeneOntologyCellularComponentdendrite

GRIK1 GRIK2 GRIK3

2.17e-02858153GO:0030425
GeneOntologyCellularComponentdendritic tree

GRIK1 GRIK2 GRIK3

2.18e-02860153GO:0097447
GeneOntologyCellularComponentendoplasmic reticulum lumen

COL6A3 STS

2.30e-02332152GO:0005788
GeneOntologyCellularComponentvacuole

GLB1L STS GPC4

2.55e-02913153GO:0005773
GeneOntologyCellularComponentcell body

GRIK1 GRIK2 GRIK3

2.67e-02929153GO:0044297
GeneOntologyCellularComponentcytoplasmic region

GRIK2 GRIK3

2.68e-02360152GO:0099568
MousePhenoabnormal body length

TNRC6B PELI1 COL6A3 GRIK3 FGL1

1.98e-05550105MP:0001256
MousePhenodecreased paired-pulse facilitation

GRIK2 GRIK3

1.37e-0425102MP:0002920
MousePhenodecreased body length

TNRC6B PELI1 COL6A3 GRIK3

2.52e-04484104MP:0001258
MousePhenoabnormal long-term potentiation

GRIK1 GRIK2 GRIK3

4.31e-04221103MP:0002207
MousePhenoabnormal glutamate-mediated receptor currents

GRIK1 GRIK2

6.70e-0455102MP:0002886
DomainPBPe

GRIK1 GRIK2 GRIK3

3.40e-0718153SM00079
DomainIono_rcpt_met

GRIK1 GRIK2 GRIK3

3.40e-0718153IPR001508
DomainGlu/Gly-bd

GRIK1 GRIK2 GRIK3

3.40e-0718153IPR019594
DomainIontro_rcpt

GRIK1 GRIK2 GRIK3

3.40e-0718153IPR001320
DomainLig_chan

GRIK1 GRIK2 GRIK3

3.40e-0718153PF00060
DomainLig_chan-Glu_bd

GRIK1 GRIK2 GRIK3

3.40e-0718153SM00918
DomainLig_chan-Glu_bd

GRIK1 GRIK2 GRIK3

3.40e-0718153PF10613
DomainANF_receptor

GRIK1 GRIK2 GRIK3

3.20e-0637153PF01094
DomainANF_lig-bd_rcpt

GRIK1 GRIK2 GRIK3

3.20e-0637153IPR001828
DomainPeripla_BP_I

GRIK1 GRIK2 GRIK3

3.76e-0639153IPR028082
DomainFibrinogen_C

ITLN2 FGL1

2.09e-0427152PF00147
DomainFBG

ITLN2 FGL1

2.41e-0429152SM00186
Domain-

ITLN2 FGL1

2.59e-04301523.90.215.10
DomainFibrinogen_a/b/g_C_1

ITLN2 FGL1

2.59e-0430152IPR014716
DomainFIBRINOGEN_C_2

ITLN2 FGL1

2.94e-0432152PS51406
DomainFibrinogen_a/b/g_C_dom

ITLN2 FGL1

2.94e-0432152IPR002181
DomainFIBRINOGEN_C_1

ITLN2 FGL1

2.94e-0432152PS00514
DomainIg_E-set

TRIM71 TGM7

3.08e-03104152IPR014756
DomainAnk_2

POTEC POTEI

1.25e-02215152PF12796
DomainAnk

POTEC POTEI

1.40e-02228152PF00023
Domain-

COL6A3 TRIM71 TGM7

1.47e-026631532.60.40.10
Domain-

POTEC POTEI

1.65e-022481521.25.40.20
DomainANK

POTEC POTEI

1.68e-02251152SM00248
DomainANK_REPEAT

POTEC POTEI

1.71e-02253152PS50088
DomainAnkyrin_rpt-contain_dom

POTEC POTEI

1.72e-02254152IPR020683
DomainANK_REP_REGION

POTEC POTEI

1.72e-02254152PS50297
DomainIg-like_fold

COL6A3 TRIM71 TGM7

1.74e-02706153IPR013783
DomainAnkyrin_rpt

POTEC POTEI

1.82e-02262152IPR002110
PathwayREACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS

GRIK1 GRIK2 GRIK3

4.23e-0810113M10272
PathwayREACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS

GRIK1 GRIK2 GRIK3

7.75e-0812113MM15142
PathwayREACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING

GRIK1 GRIK2 GRIK3

1.42e-0630113M18193
PathwayREACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING

GRIK1 GRIK2 GRIK3

1.73e-0632113MM15143
PathwayREACTOME_HS_GAG_DEGRADATION

GLB1L GPC4

1.39e-0423112MM14804
PathwayWP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING

GRIK1 GRIK2 GRIK3

1.49e-04140113M42572
PathwayREACTOME_HS_GAG_DEGRADATION

GLB1L GPC4

1.51e-0424112M636
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

GRIK1 GRIK2 GRIK3

1.62e-04144113MM14501
PathwayREACTOME_GLYCOSPHINGOLIPID_CATABOLISM

GLB1L STS

4.04e-0439112M48042
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

GRIK1 GRIK2 GRIK3

4.59e-04205113M752
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

GRIK1 GRIK2 GRIK3

4.99e-04211113MM14502
PathwayREACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM

GLB1L GPC4

7.75e-0454112MM14633
PathwayREACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM

GLB1L GPC4

8.63e-0457112M692
PathwayREACTOME_GLYCOSPHINGOLIPID_METABOLISM

GLB1L STS

8.93e-0458112M576
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

GRIK1 GRIK2 GRIK3

1.02e-03270113M15514
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

GRIK1 GRIK2 GRIK3

1.05e-03272113M13380
PathwayREACTOME_NEURONAL_SYSTEM

GRIK1 GRIK2 GRIK3

1.90e-03335113MM14503
PathwayREACTOME_SPHINGOLIPID_METABOLISM

GLB1L STS

3.00e-03107112M14857
PathwayREACTOME_NEURONAL_SYSTEM

GRIK1 GRIK2 GRIK3

3.41e-03411113M735
PathwayREACTOME_GLYCOSAMINOGLYCAN_METABOLISM

GLB1L GPC4

3.94e-03123112MM14623
PathwayREACTOME_GLYCOSAMINOGLYCAN_METABOLISM

GLB1L GPC4

4.14e-03126112M695
Pubmed

The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain.

GRIK1 GRIK2 GRIK3

6.49e-11315331513786
Pubmed

Differential trafficking of GluR7 kainate receptor subunit splice variants.

GRIK1 GRIK2 GRIK3

6.49e-11315315805114
Pubmed

Kainate receptor-mediated responses in the CA1 field of wild-type and GluR6-deficient mice.

GRIK1 GRIK2 GRIK3

6.49e-1131539880586
Pubmed

Kainate receptors and rhythmic activity in neuronal networks: hippocampal gamma oscillations as a tool.

GRIK1 GRIK2 GRIK3

2.60e-10415315513934
Pubmed

Reduced synaptic function of Kainate receptors in the insular cortex of Fmr1 Knock-out mice.

GRIK1 GRIK2 GRIK3

2.60e-10415330241548
Pubmed

Kainate receptors act as conditional amplifiers of spike transmission at hippocampal mossy fiber synapses.

GRIK1 GRIK2 GRIK3

2.60e-10415319369569
Pubmed

Developmental expression patterns of kainate receptors in the mouse spinal cord.

GRIK1 GRIK2 GRIK3

6.49e-10515323076118
Pubmed

Molecular determinants of kainate receptor trafficking.

GRIK1 GRIK2 GRIK3

6.49e-10515318358623
Pubmed

Kainate receptors: pharmacology, function and therapeutic potential.

GRIK1 GRIK2 GRIK3

6.49e-10515318793656
Pubmed

Development of laminar distributions of kainate receptors in the somatosensory cortex of mice.

GRIK1 GRIK2 GRIK3

6.49e-1051539593973
Pubmed

Complete Disruption of the Kainate Receptor Gene Family Results in Corticostriatal Dysfunction in Mice.

GRIK1 GRIK2 GRIK3

6.49e-10515328228252
Pubmed

Kainate receptor subunits underlying presynaptic regulation of transmitter release in the dorsal horn.

GRIK1 GRIK2 GRIK3

6.49e-10515312223554
Pubmed

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains.

GRIK1 GRIK2 GRIK3

6.49e-10515329058671
Pubmed

N-glycan content modulates kainate receptor functional properties.

GRIK1 GRIK2 GRIK3

1.30e-09615328714086
Pubmed

Glutamate binding and conformational flexibility of ligand-binding domains are critical early determinants of efficient kainate receptor biogenesis.

GRIK1 GRIK2 GRIK3

2.27e-09715319342380
Pubmed

Glutamate receptors: brain function and signal transduction.

GRIK1 GRIK2 GRIK3

2.27e-0971539651535
Pubmed

Glutamate receptors in cortical plasticity: molecular and cellular biology.

GRIK1 GRIK2 GRIK3

2.27e-0971539016303
Pubmed

Primary structure and expression of the gamma 2 subunit of the glutamate receptor channel selective for kainate.

GRIK1 GRIK2 GRIK3

2.27e-0971531310861
Pubmed

Short-term plasticity of kainate receptor-mediated EPSCs induced by NMDA receptors at hippocampal mossy fiber synapses.

GRIK1 GRIK2 GRIK3

2.27e-09715317428973
Pubmed

Transmembrane topology of the glutamate receptor subunit GluR6.

GRIK1 GRIK2 GRIK3

3.63e-0981538163463
Pubmed

Expression of glutamate receptor subunit genes during development of the mouse retina.

GRIK1 GRIK2 GRIK3

5.44e-0991539051806
Pubmed

Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.

GRIK1 GRIK2 GRIK3

1.85e-081315320859245
Pubmed

Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans.

GRIK1 GRIK2 GRIK3

1.14e-07231538464923
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRIK1 GRIK2 GRIK3

1.31e-072415335746896
Pubmed

Kainate receptors are involved in short- and long-term plasticity at mossy fiber synapses in the hippocampus.

GRIK1 GRIK2

1.74e-07215211182092
Pubmed

Altered long-term synaptic plasticity and kainate-induced Ca2+ transients in the substantia gelatinosa neurons in GLU(K6)-deficient mice.

GRIK1 GRIK2

1.74e-07215216219388
Pubmed

Presynaptic kainate receptors impart an associative property to hippocampal mossy fiber long-term potentiation.

GRIK1 GRIK2

1.74e-07215212947409
Pubmed

Expression and novel subunit isoforms of glutamate receptor genes GluR5 and GluR6.

GRIK1 GRIK2

1.74e-0721528260617
Pubmed

Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses.

GRIK1 GRIK2

1.74e-07215215537878
Pubmed

Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis.

GRIK1 GRIK2

1.74e-07215224760837
Pubmed

Altered behavioral responses to noxious stimuli and fear in glutamate receptor 5 (GluR5)- or GluR6-deficient mice.

GRIK1 GRIK2

1.74e-07215215673679
Pubmed

Subunit composition of kainate receptors in hippocampal interneurons.

GRIK1 GRIK2

1.74e-07215211144357
Pubmed

Kainate receptor-mediated synaptic transmission in the adult anterior cingulate cortex.

GRIK1 GRIK2

1.74e-07215215928066
Pubmed

A mosaic of functional kainate receptors in hippocampal interneurons.

GRIK1 GRIK2

1.74e-07215215483117
Pubmed

Association of markers in the 3' region of the GluR5 kainate receptor subunit gene to alcohol dependence.

GRIK1 GRIK3

1.74e-07215219320626
Pubmed

Postnatal maturation of mossy fibre excitatory transmission in mouse CA3 pyramidal cells: a potential role for kainate receptors.

GRIK1 GRIK2

1.74e-07215215358807
Pubmed

Modulation of excitatory synaptic transmission in the spinal substantia gelatinosa of mice deficient in the kainate receptor GluR5 and/or GluR6 subunit.

GRIK1 GRIK2

1.74e-07215214724198
Pubmed

GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses.

GRIK2 GRIK3

1.74e-07215217620617
Pubmed

Contribution of aberrant GluK2-containing kainate receptors to chronic seizures in temporal lobe epilepsy.

GRIK1 GRIK2

1.74e-07215225043179
Pubmed

Functional characterization of kainate receptors in the mouse nucleus accumbens.

GRIK1 GRIK2

1.74e-07215211985817
Pubmed

Frequency and transmission of glutamate receptors GRIK2 and GRIK3 polymorphisms in patients with obsessive compulsive disorder.

GRIK2 GRIK3

1.74e-07215215094479
Pubmed

Subunit composition and alternative splicing regulate membrane delivery of kainate receptors.

GRIK1 GRIK2

1.74e-07215215014126
Pubmed

RNA editing of human kainate receptor subunits.

GRIK1 GRIK2

1.74e-0721527696618
Pubmed

Atypical functional properties of GluK3-containing kainate receptors.

GRIK2 GRIK3

1.74e-07215220007474
Pubmed

Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences.

GRIK1 GRIK2

1.74e-0721528700852
Pubmed

Identification of the kainate receptor subunits underlying modulation of excitatory synaptic transmission in the CA3 region of the hippocampus.

GRIK1 GRIK2

1.74e-07215211069933
Pubmed

The kainate receptor subunit GluR6 mediates metabotropic regulation of the slow and medium AHP currents in mouse hippocampal neurones.

GRIK1 GRIK2

1.74e-07215215539395
Pubmed

Q/R site editing controls kainate receptor inhibition by membrane fatty acids.

GRIK1 GRIK2

1.74e-07215216221857
Pubmed

Distinct Subunit Domains Govern Synaptic Stability and Specificity of the Kainate Receptor.

GRIK1 GRIK2

5.21e-07315227346345
Pubmed

Cloning and functional expression of a cDNA encoding the mouse beta 2 subunit of the kainate-selective glutamate receptor channel.

GRIK1 GRIK2

5.21e-0731521379666
Pubmed

Effect of RNA editing and subunit co-assembly single-channel properties of recombinant kainate receptors.

GRIK1 GRIK2

5.21e-0731528730589
Pubmed

RNA editing of the glutamate receptor subunits GluR2 and GluR6 in human brain tissue.

GRIK1 GRIK2

5.21e-0731527523595
Pubmed

Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3.

GRIK2 GRIK3

5.21e-07315232567721
Pubmed

Changes in expression of glutamate receptor subunits following photoreceptor degeneration in the rd mouse retina.

GRIK1 GRIK3

5.21e-0731527538211
Pubmed

Distinct roles for the kainate receptor subunits GluR5 and GluR6 in kainate-induced hippocampal gamma oscillations.

GRIK1 GRIK2

5.21e-07315215509753
Pubmed

Genetic evidence for the requirement of adenylyl cyclase 1 in synaptic scaling of forebrain cortical neurons.

GRIK1 GRIK2

1.04e-06415217650106
Pubmed

Distinct subunits in heteromeric kainate receptors mediate ionotropic and metabotropic function at hippocampal mossy fiber synapses.

GRIK1 GRIK2

1.04e-06415216354929
Pubmed

The auxiliary subunits Neto1 and Neto2 have distinct, subunit-dependent effects at recombinant GluK1- and GluK2-containing kainate receptors.

GRIK1 GRIK2

1.04e-06415226277340
Pubmed

Distribution of kainate receptor subunits at hippocampal mossy fiber synapses.

GRIK2 GRIK3

1.04e-06415212954862
Pubmed

Synaptic activation of kainate receptors gates presynaptic CB(1) signaling at GABAergic synapses.

GRIK1 GRIK2

1.04e-06415220081851
Pubmed

Localization of glutamate receptors to distal dendrites depends on subunit composition and the kinesin motor protein KIF17.

GRIK1 GRIK2

1.04e-06415217174564
Pubmed

Coexistence of two forms of LTP in ACC provides a synaptic mechanism for the interactions between anxiety and chronic pain.

GRIK1 GRIK2

1.04e-06415225556835
Pubmed

Determination of kainate receptor subunit ratios in mouse brain using novel chimeric protein standards.

GRIK2 GRIK3

1.73e-06515226448475
Pubmed

Expression and heteromeric interactions of non-N-methyl-D-aspartate glutamate receptor subunits in the developing and adult cerebellum.

GRIK2 GRIK3

1.73e-0651529466455
Pubmed

Neto Auxiliary Subunits Regulate Interneuron Somatodendritic and Presynaptic Kainate Receptors to Control Network Inhibition.

GRIK1 GRIK2

1.73e-06515228854365
Pubmed

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels.

GRIK1 GRIK2

1.73e-0651521717158
Pubmed

Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP.

GRIK1 GRIK2

2.60e-06615212597860
Pubmed

The actin-binding protein Filamin-A interacts with the metabotropic glutamate receptor type 7.

GRIK1 GRIK3

2.60e-06615211943148
Pubmed

Neto1 is an auxiliary subunit of native synaptic kainate receptors.

GRIK1 GRIK2

2.60e-06615221734292
Pubmed

Maternal high-fat diet-induced microbiota changes are associated with alterations in embryonic brain metabolites and adolescent behaviour.

GRIK1 GRIK3

4.85e-06815239032541
Pubmed

Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.

GRIK1 GRIK2 GRIK3

5.43e-068115322723691
Pubmed

Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data.

GRIK1 GRIK2

6.24e-06915234100982
Pubmed

The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs.

GRIK1 GRIK2

1.14e-051215211891216
Pubmed

Excitatory glutamate is essential for development and maintenance of the piloneural mechanoreceptor.

GRIK2 GRIK3

1.82e-051515222241839
Pubmed

Inhibition of Glycolysis in Pathogenic TH17 Cells through Targeting a miR -21-Peli1-c-Rel Pathway Prevents Autoimmunity.

TNRC6B PELI1

2.08e-051615232414810
Pubmed

Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas.

GRIK1 GRIK2

4.77e-052415222534482
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

GRIK1 GRIK2 GRIK3

2.68e-0430015319086053
InteractionGRIK4 interactions

GRIK1 GRIK2 GRIK3

1.86e-088153int:GRIK4
InteractionGRIK3 interactions

GRIK1 GRIK2 GRIK3

3.99e-0810153int:GRIK3
InteractionGRIK5 interactions

GRIK1 GRIK2 GRIK3

3.77e-0720153int:GRIK5
InteractionGRIK2 interactions

GRIK1 GRIK2 GRIK3

1.63e-0632153int:GRIK2
InteractionGRIK1 interactions

GRIK1 GRIK2 GRIK3

2.35e-0636153int:GRIK1
InteractionSCGB2A1 interactions

GLB1L ITLN2 GPC4

5.81e-05104153int:SCGB2A1
GeneFamilyGlutamate ionotropic receptor kainate type subunits

GRIK1 GRIK2 GRIK3

3.69e-0951431199
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEC POTEI

4.32e-0513142685
GeneFamilyFibrinogen C domain containing

ITLN2 FGL1

1.65e-0425142554
GeneFamilyAnkyrin repeat domain containing

POTEC POTEI

1.46e-02242142403
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL6A3 GRIK1 GRIK2

1.07e-051311539ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GRIK2 GPC4

1.67e-051521538ff5a178a8f3550d89a003c0858820aab3773386
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRIK2 GRIK3 POTEI

2.29e-05169153b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRIK1 GRIK2 POTEI

2.29e-0516915396a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellwk_15-18-Epithelial-PNS-COL20A1+_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GRIK1 GRIK2 GRIK3

2.63e-05177153b8cc6a7abf83a9844a5293b6cc4b19135b51fd53
ToppCellwk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GRIK1 GRIK2 POTEI

2.91e-051831538820cfed27b292bc0bc9cde4005219ed41900552
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PELI1 COL6A3 GPC4

3.05e-05186153db4d9ac89cc1e55062ba888b3410b773340595dd
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PELI1 COL6A3 GPC4

3.10e-051871536820bfbe552ea5e62cfe699687b051a17d9fda61
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK1 GRIK2 GRIK3

3.10e-0518715385f1678338a47d91e296f0620d4887f057eb7e70
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK1 GRIK2 GRIK3

3.35e-05192153dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK1 GRIK2 GRIK3

3.40e-051931532189da4b727e25e62669d7b9257f06493be21a27
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK1 GRIK2 GRIK3

3.40e-05193153e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK1 GRIK2 GRIK3

3.40e-05193153c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK1 GRIK2 GRIK3

3.40e-05193153658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK1 GRIK2 GRIK3

3.40e-05193153d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK1 GRIK2 GRIK3

3.40e-051931538b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A3 GRIK3 FGL1

3.40e-05193153549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK1 GRIK2 GRIK3

3.40e-05193153010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK1 GRIK2 GRIK3

3.40e-051931533ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK1 GRIK2 GRIK3

3.46e-051941531bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6-|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-05200153a9cdddc4e985dae59521e557479c24fcc2ac727d
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-05200153858421b91f5207b7934b5c219752cb9322a3da31
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-052001539719fabddc34051949468a7520289e3c750de4f8
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A--L4-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-05200153cb1f4b0d66da5b0466ff17b29e7034d451d93e4f
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-05200153347a510755374c6a66acee326565dfc447993f18
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-05200153310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-052001538d51b4f7b7002ee51401ebe5eaca1e8f04bfadd5
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-05200153107854f4855fc99c9f7e737eb246f0d868e6c5fd
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A-|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-052001531a04331862079092bc04b1010aa9228c0fa3d8c5
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-05200153c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-05200153a7022762c1d8aedb7b3e9605873b1e68b9907b35
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-052001534fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-05200153fb56d430957e73fba17db7bc0127ecf3577e0867
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-05200153f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-0520015305bcde6ce8f1354ef65e4eb9cbd963a92108081c
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-05200153cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-052001532131c8e7fa054b79906eaf60536da892438b09cd
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-05200153961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A-|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-052001536a44439e4a7ce3627271375b04cfcfb9467218f4
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6--L3-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK1 GRIK2 GRIK3

3.79e-0520015333b9199e0dfc267e2cea20b82d1c167f8adcc635
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PELI1 FGL1

3.56e-0484152db96d45e863d04a9b340c9229576d654dce85a3f
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PELI1 FGL1

3.56e-0484152152807da52b50713fc6fed2b2bef5d5762e9c0da
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocyte.Tnr.Pdgfa_(Pdgfa)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PELI1 FGL1

3.56e-0484152a88bdb8ea8a50df38fb740515d02aa87293e5d25
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GRIK3

6.43e-04113152feb3c6a7723263d58e5ce020a0097fedfcf78ca8
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GPC4

7.00e-041181523f0a304ef9c9e5ba047fc09f4372590eed624328
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Proliferative_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIK2 FGL1

8.36e-041291520dcce7cb95bb3593626ecb34ed9da58c7de4e016
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GRIK3

8.36e-041291526bc85761dea1f97c19bb379a99e4daf85d53201e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GRIK2

8.49e-0413015260e28d452d0e2af768459ba8dbe998117c94a251
ToppCellParenchymal-NucSeq-Stromal-Schwann-Schwann_nonmyelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GRIK2 GRIK3

8.88e-04133152b4e68a9a223e5188f1a00c7dc9bb2d675cde1d40
ToppCellParenchymal-NucSeq-Stromal-Schwann|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GRIK2 GRIK3

8.88e-041331528819fd897b97812355e1709fcc42754522d5fb27
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GRIK3

9.28e-04136152e3a2425ba5ef538dbacab1479e682837ae42a888
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GPC4

9.83e-041401522c44e8cc5190226049be7ebc465d685393e701c4
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GRIK3

9.97e-04141152ad9a25569c142fb68ded34aeba0cd9be8124ce56
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Astrocyte|GW09 / Sample Type, Dataset, Time_group, and Cell type.

STS GPC4

1.01e-0314215285e573616e54d41391b4ad8c3d38e4ca92112673
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GRIK3

1.03e-0314315224fd24846fbef049af669a57d42fcc18928d2b27
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

POTEC GPC4

1.11e-03149152a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

POTEC GPC4

1.11e-03149152c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellRV-16._Neuronal|World / Chamber and Cluster_Paper

GRIK2 GRIK3

1.11e-031491523a2f8c4173dcf9e3f8d3b8ffddbc597098adf7a9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FGL1 GPC4

1.17e-03153152499670e716fc85ce76630fc813cec86f8419f2a1
ToppCellRV-16._Neuronal|RV / Chamber and Cluster_Paper

GRIK2 GRIK3

1.17e-03153152bed8bbf5c5cbfbf46a816066da472c3fdddecb5d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.19e-0315415242bd8f88fd075a2d4edde394785decad88a2660a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.19e-031541526425d9861148586466febd6eceae1b1f9b9a14c1
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GRIK3

1.19e-03154152a2adaa4a6cd8708cd579b8efbeb4ff2131c5482e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.19e-0315415230cb4bb297fa815adb829f3b5cafca56fcbcb810
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.19e-03154152ade094e2947761a0a34daa8fcff3e9ea8437e4a5
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRIM71 POTEI

1.20e-03155152498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCellPCW_13-14-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GRIK2 GRIK3

1.22e-031561528353f98e7d393d4299ed1da8f66cfbc7176df1b5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

POTEC GPC4

1.22e-03156152dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

POTEC GPC4

1.22e-03156152abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGL1 GPC4

1.23e-03157152ed9c9feefc06c9536c03bedbc3397a2ee492a78e
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGL1 GPC4

1.23e-03157152fddcb24776b9f86e000208bae54541b15b2adefd
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GRIK3

1.23e-03157152741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GRIK2

1.23e-03157152516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.28e-0316015214dfa519e68bab4bce890ddb66fa7763f18d9f19
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.28e-031601525b7789d4668ed7732babedc32d812233b430e0bd
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

GRIK2 ITLN2

1.28e-0316015258ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.28e-03160152bba1486faaad5299e10f4fe17c6d149c28dc2560
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.28e-03160152839bbdfd4e4c7b48260c8bfb7670378634405e1d
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GRIK2 GRIK3

1.30e-03161152bb9cb42882aaa4a1ecf9b480c0e7ac302f2c0d5d
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GRIK3

1.30e-03161152dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCellIPF-Epithelial-PNEC|World / Disease state, Lineage and Cell class

GRIK2 GRIK3

1.30e-03161152133833729ba8b6d3eef326590ca7476b17602cbb
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GLB1L GPC4

1.30e-0316115282ed45f144a07856fe92d37426c5f92e259a03a9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.31e-03162152d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCellTCGA-Stomach-Solid_Tissue_Normal-Stomach_normal_tissue-Stomach_normal_tissue-7|TCGA-Stomach / Sample_Type by Project: Shred V9

GRIK2 GRIK3

1.31e-03162152b115b5799137122bd60696f8ae2aebadad6cd044
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.31e-031621525bbd7130d4dad9035e73a439dda568195c136f31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.31e-03162152eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.31e-03162152e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL6A3 GPC4

1.31e-0316215256f1789e69a6cb29956e46aba92b290847327c1f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRIK1 GRIK2

1.33e-031631528d17f44faf0549fe71a9a45f811f50d767275414
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRIK2 POTEI

1.34e-03164152be49af6335f2505065cde2cb9800e4a5516811b1
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

GRIK2 GRIK3

1.36e-031651526ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK1 GLB1L

1.38e-03166152c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.38e-03166152f742d15b02a6f651bbd00f53e3d871f40d05a03d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.38e-03166152e941df9a1091164edde3def8fc7d410186b2bd88
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.38e-03166152aeda46bea5d8463c24a83b98b9ed92d962d733e5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIK2 GRIK3

1.38e-031661520f013bb5fdb72e88c2fc73d60cd01551a2db6341
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRIM71 GRIK2

1.38e-03166152eb9c81fa7573de7aff6670e7dad313f02129809f
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRIK2 GRIK3

1.39e-03167152c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 GRIK2

1.39e-031671523e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GRIK2 GRIK3

1.39e-0316715249b19159c62d33d65ed1e59a148c11ae902fd41c
ComputationalIon channels.

GRIK1 GRIK2 GRIK3

5.58e-0570123MODULE_316
DrugLY339434

GRIK1 GRIK2 GRIK3

1.94e-089153CID006324635
Drugdecahydroisoquinoline

GRIK1 GRIK2 GRIK3

1.29e-0716153CID000097812
DrugLY382884

GRIK1 GRIK2 GRIK3

2.23e-0719153CID000656723
DrugNS 102

GRIK1 GRIK2 GRIK3

3.54e-0722153CID005282252
Drug5-nitro-6,7,8,9-tetrahydrobenzo(G)indole-2,3-dione-3-oxime

GRIK1 GRIK2

4.05e-072152ctd:C084273
DrugLY293558

GRIK1 GRIK2 GRIK3

9.29e-0730153CID000127894
Drug4-methylglutamic acid

GRIK1 GRIK2 GRIK3

1.03e-0631153CID000005365
Drugwillardine

GRIK1 GRIK2 GRIK3

1.13e-0632153CID000005123
DrugL-BMAA

GRIK1 GRIK2 GRIK3

1.92e-0638153CID000028558
DrugDETC-MeSO

GRIK1 GRIK2 GRIK3

2.08e-0639153CID003035711
Drugaminothiazole 6

GRIK1 GRIK3

2.43e-064152CID005329388
Drugacromelic acid B

GRIK1 GRIK3

2.43e-064152CID000158974
DrugBrn 1074551

GRIK1 GRIK3

2.43e-064152CID000120220
DrugdiCl-HQC

GRIK1 GRIK3

2.43e-064152CID003018579
DrugJoro spider toxin

GRIK1 GRIK2 GRIK3

2.81e-0643153CID000119582
Drugphilanthotoxin

GRIK1 GRIK2 GRIK3

3.23e-0645153CID000115201
Drug3-hydroxy-2-quinoxalinecarboxylic acid

GRIK1 GRIK3

4.05e-065152CID000071001
Drugbromowillardiine

GRIK1 GRIK3

4.05e-065152CID000167842
Drugipenoxazone

GRIK1 GRIK3

4.05e-065152CID000065882
DrugpBB-PzDA

GRIK1 GRIK3

4.05e-065152CID000124528
DrugAC1L1FA8

GRIK1 GRIK2 GRIK3

4.45e-0650153CID000003150
DrugLY354740

GRIK1 GRIK2 GRIK3

4.73e-0651153CID000114827
DrugAC1L1EKQ

GRIK1 GRIK2 GRIK3

5.01e-0652153CID000002834
Drug3-acetylisoquinoline

GRIK1 GRIK3

6.07e-066152CID000124656
DrugGYKI 52466

GRIK1 GRIK2 GRIK3

6.98e-0658153CID000003538
Drug3,7-diaminoheptan-2-one

GRIK1 GRIK2 GRIK3

8.14e-0661153CID004477684
Drugfluorocyclobutane

GRIK1 GRIK3

8.49e-067152CID011051569
DrugAC1L1J7N

GRIK1 GRIK2 STS

9.41e-0664153CID000004902
DrugL-Glutamic Acid

GRIK1 GRIK2 GRIK3

1.13e-0568153DB00142
DrugAC1L1B65

GRIK1 GRIK3

1.13e-058152CID000001300
Drugperzinfotel

GRIK1 GRIK3

1.13e-058152CID006918236
Drugfelbamate

GRIK1 GRIK2 GRIK3

1.23e-0570153CID000003331
DrugLy294486

GRIK1 GRIK3

1.45e-059152CID005311255
Drug1m5b

GRIK1 GRIK2

1.45e-059152CID000447081
Drugbenzo(F)quinoxaline

GRIK1 GRIK3

1.45e-059152CID000098494
DrugAC1L1E5T

GRIK1 GRIK2 GRIK3

1.46e-0574153CID000002653
DrugAC1L1DME

GRIK1 GRIK2 GRIK3

1.52e-0575153CID000002414
DrugHFPA

GRIK1 GRIK3

1.82e-0510152CID003035614
DrugBenzoates

GRIK1 GRIK2

1.82e-0510152ctd:D001565
DrugD-N-Q

GRIK1 GRIK2 GRIK3

2.13e-0584153CID000003140
DrugAC1L1BXF

GRIK1 GRIK2 GRIK3

2.21e-0585153CID000001650
Drugsym 2206

GRIK1 GRIK3

2.22e-0511152CID005039877
Drughexachlorophene

GRIK1 GRIK2 GRIK3

2.63e-0590153CID000003598
DrugAtpa

GRIK1 GRIK3

2.66e-0512152CID000002252
Drugaurintricarboxylic acid

GRIK1 GRIK2 GRIK3

2.71e-0591153CID000002259
Drug1xa5

GRIK1 GRIK2 GRIK3

2.90e-0593153CID000157684
Drugcyclothiazide

GRIK1 GRIK2 GRIK3

3.93e-05103153CID000002910
DrugACEA-1011

GRIK1 GRIK3

4.23e-0515152CID000127872
Drugargiopine

GRIK1 GRIK3

4.84e-0516152CID000122294
Drug3HPG

GRIK1 GRIK3

5.48e-0517152CID000001217
Drugacromelic acid A

GRIK1 GRIK3

6.16e-0518152CID000108086
Drugkynurenic acid

GRIK1 GRIK2 GRIK3

6.52e-05122153CID000003845
DrugLinuron

GRIK1 GRIK2 STS

7.52e-05128153ctd:D008044
DrugIDRA 21

GRIK1 GRIK3

7.64e-0520152CID000003688
Drug4-carboxy-3-hydroxyphenylglycine

GRIK1 GRIK3

7.64e-0520152CID000001297
Druganiracetam

GRIK1 GRIK2 GRIK3

7.87e-05130153CID000002196
DrugAC1L1B62

GRIK1 GRIK3

8.45e-0521152CID000001299
DrugCelecoxib

GRIK1 GRIK2 GRIK3 STS

8.65e-05376154ctd:D000068579
DrugCX516

GRIK1 GRIK3

9.29e-0522152CID000148184
Drughaloperidol

COL6A3 GRIK1 GRIK2 GRIK3

1.04e-04394154CID000003559
DrugDE gel

GRIK1 GRIK2 GRIK3

1.04e-04143153CID000008146
DrugNs102

GRIK1 GRIK3

1.20e-0425152CID005311098
Drugputrescine

GRIK1 POTEC TGM7

1.28e-04153153CID000001045
Drugprocymidone

GRIK1 GRIK2 STS

1.33e-04155153ctd:C035988
Drug2-chloropropionate

GRIK1 GRIK3

1.41e-0427152CID000011734
DrugAC1NUW3V

GRIK1 GRIK3

1.63e-0429152CID005462126
Drugcis-2,3-piperidine dicarboxylic acid

GRIK1 GRIK3

1.74e-0430152CID000001226
Drugriluzole

GRIK1 GRIK2 GRIK3

1.87e-04174153CID000005070
DrugL-quisqualic acid

GRIK1 GRIK2 GRIK3

2.06e-04180153CID000001209
DrugTG-3

GRIK1 TGM7

2.11e-0433152CID000205489
Drug6,7-dinitroquinoxaline

GRIK1 GRIK3

2.11e-0433152CID002724608
DrugCPPG

GRIK1 GRIK3

2.25e-0434152CID000002878
Drugkainite

GRIK1 GRIK3

2.38e-0435152CID000164810
DrugR,S)-AMPA

GRIK1 GRIK3

2.52e-0436152CID000001221
Drug2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A

GRIK2 FGL1 STS

2.53e-041931532682_UP
DrugPF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A

GRIK2 GLB1L STS

2.53e-041931535922_UP
DrugKainic Acid

GRIK1 GRIK2 GRIK3

2.57e-04194153ctd:D007608
DrugAvermectin B1 [71751-41-2]; Up 200; 4.8uM; MCF7; HT_HG-U133A

COL6A3 GLB1L STS

2.57e-041941536081_UP
DrugFlumethasone [2135-17-3]; Up 200; 9.8uM; MCF7; HT_HG-U133A

COL6A3 FGL1 STS

2.57e-041941533610_UP
Drug3-nitropropionic acid; Down 200; 10uM; MCF7; HT_HG-U133A

GRIK1 FGL1 STS

2.65e-041961536367_DN
Drugestradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA

TNRC6B GLB1L STS

2.65e-041961531021_DN
DrugLithocholic acid [434-13-9]; Down 200; 10.6uM; PC3; HT_HG-U133A

TNRC6B GLB1L STS

2.65e-041961533816_DN
DrugDiazoxide [364-98-7]; Up 200; 17.4uM; PC3; HT_HG-U133A

TNRC6B GRIK2 STS

2.65e-041961532052_UP
Druggamma-Glu-Gly

GRIK1 GRIK3

2.66e-0437152CID000100099
DrugKynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A

GRIK1 GRIK2 GLB1L

2.69e-041971535641_UP
DrugXylazine [7361-61-7]; Down 200; 18.2uM; PC3; HT_HG-U133A

TNRC6B STS GPC4

2.69e-041971534066_DN
DrugICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A

COL6A3 GRIK3 FGL1

2.69e-041971535964_UP
DrugNadide [53-84-9]; Down 200; 6uM; MCF7; HT_HG-U133A

TNRC6B FGL1 STS

2.69e-041971536091_DN
DrugFlutamide [13311-84-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A

GLB1L STS GPC4

2.69e-041971533885_DN
DrugAlprostadil [745-65-3]; Down 200; 11.2uM; PC3; HT_HG-U133A

GRIK2 FGL1 STS

2.73e-041981534099_DN
DrugBetahistine mesylate [54856-23-4]; Up 200; 17.2uM; PC3; HT_HG-U133A

GRIK1 GLB1L STS

2.73e-041981536611_UP
DrugXylazine [7361-61-7]; Up 200; 18.2uM; MCF7; HT_HG-U133A

COL6A3 GLB1L STS

2.73e-041981534147_UP
DrugPirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A

GRIK1 GLB1L STS

2.73e-041981535639_UP
DrugTrimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A

PELI1 GLB1L STS

2.73e-041981531502_UP
DrugDorzolamide hydrochloride [130693-82-2]; Up 200; 11uM; HL60; HT_HG-U133A

GRIK2 STS GPC4

2.73e-041981536142_UP
DrugArcaine sulfate [14923-17-2]; Up 200; 14.8uM; PC3; HT_HG-U133A

GRIK2 GLB1L STS

2.77e-041991536629_UP
DrugGuanadrel sulfate [22195-34-2]; Down 200; 7.6uM; PC3; HT_HG-U133A

GLB1L FGL1 STS

2.77e-041991533698_DN
DrugGAMs

GRIK1 GRIK3

2.81e-0438152CID000002935
DrugCGS 19755

GRIK1 GRIK3

2.81e-0438152CID000068736
Drug3-C-4

PELI1 COL6A3

2.81e-0438152CID000118534
Diseaseneurodegenerative disease (implicated_via_orthology)

GRIK1 GRIK2 GRIK3

3.21e-05145133DOID:1289 (implicated_via_orthology)
DiseaseBilateral Wilms Tumor

COL6A3 GPC4

7.23e-0529132C2930471
DiseaseNephroblastoma

COL6A3 GPC4

1.12e-0436132C0027708
DiseaseAlzheimer disease, APOE carrier status

COL6A3 GRIK3

8.32e-0498132EFO_0007659, MONDO_0004975
Diseaseascending aortic diameter

TNRC6B COL6A3

1.68e-03140132EFO_0021787
Diseaseunipolar depression, bipolar disorder

GRIK2 GRIK3

2.08e-03156132EFO_0003761, MONDO_0004985
Diseaserisky sexual behaviour measurement

GRIK1 GRIK2

2.44e-03169132EFO_0007877
Diseaseaortic measurement

TNRC6B COL6A3

5.28e-03251132EFO_0020865
DiseaseAlcoholic Intoxication, Chronic

GRIK1 GRIK3

6.00e-03268132C0001973
DiseaseSchizophrenia

GRIK1 GRIK2 GRIK3

6.10e-03883133C0036341
Diseaseneuroticism measurement

PELI1 GRIK1 GRIK3

6.61e-03909133EFO_0007660

Protein segments in the cluster

PeptideGeneStartEntry
DGKYGAQNDKGEWNG

GRIK1

501

P39086
GEKGTKNGQFNYPWD

TRIM71

691

Q2Q1W2
GNGNEDDCWNGKGKS

GPC4

416

O75487
ENFNRGWKDYENGFG

FGL1

131

Q08830
GWKDYENGFGNFVQK

FGL1

136

Q08830
WYGGCGGNENKFGSQ

COL6A3

3141

P12111
GGTNFGYWNGADKKG

GLB1L

306

Q6UWU2
QGNKADYPEGDGNWA

ITLN2

116

Q8WWU7
GKYGAQDDANGQWNG

GRIK2

486

Q13002
VEDGKYGAQDDKGQW

GRIK3

486

Q13003
YGAQDDKGQWNGMVK

GRIK3

491

Q13003
GYHNWGNKEERDGKD

PELI1

316

Q96FA3
GSGKSNVGAWGDYDD

POTEC

111

B2RU33
NGIYKGGKANNWEGG

STS

361

P08842
GSGKSNVGAWGDYDD

POTEI

111

P0CG38
NGVLQGNWGEDYSKG

TGM7

236

Q96PF1
DPKNTGGWNDYKNNN

TNRC6B

691

Q9UPQ9