Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription coregulator activity

MED12L MED15 MIDEAS SUPT20HL1 NCOR2 MAML3 NCOA6 EP300 NOTCH1 KMT2D SUPT20H

7.93e-125622311GO:0003712
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

MED12L MED15 MIDEAS SUPT20HL1 NCOR2 MAML3 NCOA6 EP300 NOTCH1 KMT2D SUPT20H

1.72e-0811602311GO:0030674
GeneOntologyMolecularFunctionmolecular adaptor activity

MED12L MED15 MIDEAS SUPT20HL1 NCOR2 MAML3 NCOA6 EP300 NOTCH1 KMT2D SUPT20H

8.59e-0813562311GO:0060090
GeneOntologyMolecularFunctiontranscription coactivator activity

MED12L MAML3 NCOA6 EP300 NOTCH1 KMT2D

9.44e-07303236GO:0003713
GeneOntologyMolecularFunctionnuclear glucocorticoid receptor binding

NCOR2 NCOA6 EP300

1.50e-0620233GO:0035259
GeneOntologyMolecularFunctiontranscription factor binding

MED12L FOXP2 NFAT5 NCOR2 NCOA6 EP300 ARID2

1.52e-05753237GO:0008134
GeneOntologyMolecularFunctionnuclear receptor binding

FOXP2 NCOR2 NCOA6 EP300

5.74e-05187234GO:0016922
GeneOntologyMolecularFunctionchromatin binding

MBD5 NFAT5 NCOR2 NCOA6 EP300 NOTCH1

1.48e-04739236GO:0003682
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

NCOA6 EP300

2.63e-0421232GO:0042975
GeneOntologyMolecularFunctionnuclear retinoid X receptor binding

NCOR2 NCOA6

3.16e-0423232GO:0046965
GeneOntologyMolecularFunctionNotch binding

NCOR2 NOTCH1

4.38e-0427232GO:0005112
GeneOntologyMolecularFunctionnuclear androgen receptor binding

FOXP2 EP300

6.56e-0433232GO:0050681
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

FOXP2 NCOR2 NCOA6 EP300

1.21e-03417234GO:0061629
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

NCOR2 NCOA6

1.82e-0355232GO:0042974
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

FOXP2 NCOR2 NCOA6 EP300

4.07e-03582234GO:0140297
GeneOntologyMolecularFunctionbeta-catenin binding

MED12L EP300

8.34e-03120232GO:0008013
GeneOntologyMolecularFunctiontranscription coregulator binding

FOXP2 EP300

1.12e-02140232GO:0001221
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

MED12L MED15 NFAT5 SUPT20HL1 CCNK MAML3 NCOA6 EP300 ARID2 NOTCH1 KMT2D SUPT20H

5.64e-0913902312GO:0045944
GeneOntologyBiologicalProcessembryo development

FOXP2 SUPT20HL1 NCOR2 CCNK NCOA6 EP300 ARID2 NOTCH1 KMT2D SUPT20H

1.29e-0614372310GO:0009790
GeneOntologyBiologicalProcesspositive regulation of transcription of Notch receptor target

MAML3 NOTCH1

2.49e-057232GO:0007221
GeneOntologyBiologicalProcesscoronary artery morphogenesis

ARID2 NOTCH1

5.32e-0510232GO:0060982
GeneOntologyBiologicalProcessDNA damage response

NFAT5 SUPT20HL1 CCNK NCOA6 EP300 ARID2 SUPT20H

5.85e-05959237GO:0006974
GeneOntologyBiologicalProcessregulation of gluconeogenesis

SUPT20HL1 EP300 SUPT20H

6.59e-0571233GO:0006111
GeneOntologyBiologicalProcessregulation of intracellular steroid hormone receptor signaling pathway

NCOR2 EP300 KMT2D

1.21e-0487233GO:0033143
GeneOntologyBiologicalProcesslung development

FOXP2 NCOR2 EP300 NOTCH1

2.06e-04269234GO:0030324
GeneOntologyBiologicalProcessrespiratory tube development

FOXP2 NCOR2 EP300 NOTCH1

2.18e-04273234GO:0030323
GeneOntologyBiologicalProcessgluconeogenesis

SUPT20HL1 EP300 SUPT20H

2.48e-04111233GO:0006094
GeneOntologyBiologicalProcesshexose biosynthetic process

SUPT20HL1 EP300 SUPT20H

2.76e-04115233GO:0019319
GeneOntologyBiologicalProcessmonosaccharide biosynthetic process

SUPT20HL1 EP300 SUPT20H

3.20e-04121233GO:0046364
GeneOntologyBiologicalProcessrespiratory system development

FOXP2 NCOR2 EP300 NOTCH1

3.32e-04305234GO:0060541
GeneOntologyBiologicalProcesschordate embryonic development

NCOR2 CCNK NCOA6 EP300 NOTCH1 KMT2D

3.75e-04906236GO:0043009
GeneOntologyBiologicalProcesshead development

FOXP2 NCOR2 NCOA6 EP300 NOTCH1 JHY

4.05e-04919236GO:0060322
GeneOntologyBiologicalProcessregulation of carbohydrate biosynthetic process

SUPT20HL1 EP300 SUPT20H

4.13e-04132233GO:0043255
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

NCOR2 CCNK NCOA6 EP300 NOTCH1 KMT2D

4.29e-04929236GO:0009792
GeneOntologyBiologicalProcessregulation of glucose metabolic process

SUPT20HL1 EP300 SUPT20H

4.32e-04134233GO:0010906
GeneOntologyBiologicalProcessin utero embryonic development

NCOR2 CCNK NCOA6 NOTCH1 KMT2D

4.33e-04596235GO:0001701
GeneOntologyBiologicalProcessnuclear receptor-mediated steroid hormone signaling pathway

NCOR2 EP300 KMT2D

4.51e-04136233GO:0030518
GeneOntologyBiologicalProcesscardiac muscle tissue growth

EP300 ARID2 NOTCH1

4.70e-04138233GO:0055017
GeneOntologyBiologicalProcessregulation of androgen receptor signaling pathway

NCOR2 EP300

5.42e-0431232GO:0060765
GeneOntologyBiologicalProcessheart growth

EP300 ARID2 NOTCH1

5.77e-04148233GO:0060419
GeneOntologyBiologicalProcesspositive regulation of gluconeogenesis

SUPT20HL1 SUPT20H

5.78e-0432232GO:0045722
GeneOntologyBiologicalProcessnegative regulation of stem cell differentiation

CCNK NOTCH1

6.15e-0433232GO:2000737
GeneOntologyBiologicalProcessregulation of protein deacetylation

NCOR2 EP300

6.53e-0434232GO:0090311
GeneOntologyBiologicalProcessnegative regulation of miRNA metabolic process

NCOR2 EP300

6.53e-0434232GO:2000629
GeneOntologyBiologicalProcesscoronary vasculature morphogenesis

ARID2 NOTCH1

6.53e-0434232GO:0060977
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

NCOR2 EP300 KMT2D

6.60e-04155233GO:0043401
GeneOntologyBiologicalProcessresponse to hormone

MBD5 NCOR2 NCOA6 EP300 NOTCH1 KMT2D

7.88e-041042236GO:0009725
GeneOntologyBiologicalProcesscellular response to hormone stimulus

MBD5 NCOR2 EP300 NOTCH1 KMT2D

1.06e-03727235GO:0032870
GeneOntologyBiologicalProcessregulation of small molecule metabolic process

SUPT20HL1 NCOR2 EP300 SUPT20H

1.25e-03434234GO:0062012
GeneOntologyBiologicalProcessprotein deacetylation

NCOR2 EP300

1.25e-0347232GO:0006476
GeneOntologyBiologicalProcessheart development

NCOR2 NCOA6 EP300 ARID2 NOTCH1

1.27e-03757235GO:0007507
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

NCOR2 EP300 KMT2D

1.42e-03202233GO:0141193
GeneOntologyBiologicalProcessandrogen receptor signaling pathway

NCOR2 EP300

1.47e-0351232GO:0030521
GeneOntologyBiologicalProcesspositive regulation of transcription elongation by RNA polymerase II

MED15 CCNK

1.64e-0354232GO:0032968
GeneOntologyBiologicalProcesspositive regulation of cardiac muscle tissue growth

EP300 NOTCH1

1.77e-0356232GO:0055023
GeneOntologyBiologicalProcessskeletal muscle tissue development

FOXP2 EP300 NOTCH1

1.88e-03223233GO:0007519
GeneOntologyBiologicalProcessviral transcription

EP300 NOTCH1

1.89e-0358232GO:0019083
GeneOntologyBiologicalProcesspositive regulation of receptor signaling pathway via JAK-STAT

EP300 NOTCH1

1.89e-0358232GO:0046427
GeneOntologyBiologicalProcessprotein deacylation

NCOR2 EP300

1.89e-0358232GO:0035601
GeneOntologyBiologicalProcessgrowth

MBD5 FOXP2 EP300 ARID2 NOTCH1 KMT2D

1.90e-031235236GO:0040007
GeneOntologyBiologicalProcessresponse to acid chemical

CPEB3 NFAT5 EP300

2.00e-03228233GO:0001101
GeneOntologyBiologicalProcesspositive regulation of heart growth

EP300 NOTCH1

2.02e-0360232GO:0060421
GeneOntologyBiologicalProcessDNA-templated transcription initiation

MED15 NCOA6 EP300

2.08e-03231233GO:0006352
GeneOntologyBiologicalProcessregulation of carbohydrate metabolic process

SUPT20HL1 EP300 SUPT20H

2.08e-03231233GO:0006109
GeneOntologyBiologicalProcesslung epithelium development

FOXP2 NCOR2

2.09e-0361232GO:0060428
GeneOntologyBiologicalProcessregulation of DNA repair

SUPT20HL1 ARID2 SUPT20H

2.16e-03234233GO:0006282
GeneOntologyBiologicalProcesspositive regulation of DNA-templated transcription, elongation

MED15 CCNK

2.16e-0362232GO:0032786
GeneOntologyBiologicalProcessanimal organ morphogenesis

FOXP2 NCOR2 EP300 ARID2 NOTCH1 JHY

2.18e-031269236GO:0009887
GeneOntologyBiologicalProcessbrain development

FOXP2 NCOR2 NCOA6 NOTCH1 JHY

2.23e-03859235GO:0007420
GeneOntologyBiologicalProcessmacromolecule deacylation

NCOR2 EP300

2.23e-0363232GO:0098732
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

NCOR2 EP300 KMT2D

2.29e-03239233GO:0071383
GeneOntologyBiologicalProcesspositive regulation of glucose metabolic process

SUPT20HL1 SUPT20H

2.30e-0364232GO:0010907
GeneOntologyBiologicalProcessT-helper 17 type immune response

EP300 NOTCH1

2.30e-0364232GO:0072538
GeneOntologyBiologicalProcessskeletal muscle organ development

FOXP2 EP300 NOTCH1

2.32e-03240233GO:0060538
GeneOntologyBiologicalProcessregulation of collagen biosynthetic process

EP300 NOTCH1

2.37e-0365232GO:0032965
GeneOntologyBiologicalProcesspositive regulation of receptor signaling pathway via STAT

EP300 NOTCH1

2.37e-0365232GO:1904894
GeneOntologyBiologicalProcessglucose metabolic process

SUPT20HL1 EP300 SUPT20H

2.43e-03244233GO:0006006
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

NCOR2 EP300 KMT2D

2.43e-03244233GO:0009755
GeneOntologyCellularComponenttranscription regulator complex

MED15 NFAT5 MIDEAS NCOR2 NCOA6 EP300 ARID2

1.74e-06596227GO:0005667
GeneOntologyCellularComponentnuclear protein-containing complex

MED12L MED15 MIDEAS NCOR2 CCNK NCOA6 ARID2 KMT2D

4.82e-051377228GO:0140513
GeneOntologyCellularComponentMLL3/4 complex

NCOA6 KMT2D

6.93e-0512222GO:0044666
GeneOntologyCellularComponenthistone acetyltransferase complex

SUPT20HL1 EP300 SUPT20H

1.27e-0494223GO:0000123
GeneOntologyCellularComponentprotein acetyltransferase complex

SUPT20HL1 EP300 SUPT20H

1.72e-04104223GO:0031248
GeneOntologyCellularComponentacetyltransferase complex

SUPT20HL1 EP300 SUPT20H

1.98e-04109223GO:1902493
GeneOntologyCellularComponentSAGA complex

SUPT20HL1 SUPT20H

3.13e-0425222GO:0000124
GeneOntologyCellularComponenttransferase complex

SUPT20HL1 CCNK NCOA6 EP300 KMT2D SUPT20H

3.72e-04963226GO:1990234
GeneOntologyCellularComponentchromatin

FOXP2 NFAT5 SUPT20HL1 NCOR2 EP300 ARID2 SUPT20H

5.82e-041480227GO:0000785
GeneOntologyCellularComponentSAGA-type complex

SUPT20HL1 SUPT20H

7.65e-0439222GO:0070461
GeneOntologyCellularComponenthistone methyltransferase complex

NCOA6 KMT2D

2.80e-0375222GO:0035097
GeneOntologyCellularComponenthistone deacetylase complex

MIDEAS NCOR2

3.58e-0385222GO:0000118
GeneOntologyCellularComponentmethyltransferase complex

NCOA6 KMT2D

5.71e-03108222GO:0034708
GeneOntologyCellularComponentpeptidase complex

SUPT20HL1 SUPT20H

8.54e-03133222GO:1905368
GeneOntologyCellularComponentnuclear matrix

NCOR2 ARID2

9.42e-03140222GO:0016363
HumanPhenoThin vermilion border

MBD5 MED12L CCNK HS6ST2 EP300 ARID2 KMT2D QRICH1

9.90e-08433108HP:0000233
HumanPhenoThin upper lip vermilion

MBD5 MED12L CCNK EP300 ARID2 KMT2D QRICH1

5.49e-07339107HP:0000219
HumanPhenoThin lips

MBD5 MED12L CCNK EP300 ARID2 KMT2D QRICH1

5.49e-07339107HP:0000213
HumanPhenoProminent fingertip pads

MED12L FOXP2 EP300 KMT2D

1.18e-0646104HP:0001212
HumanPhenoProminent digit pad

MED12L FOXP2 EP300 KMT2D

1.40e-0648104HP:0011298
HumanPhenoAutistic behavior

MBD5 MED12L FOXP2 CCNK EP300 ARID2 KMT2D QRICH1

3.33e-06678108HP:0000729
HumanPhenoAbnormality of upper lip vermillion

MBD5 MED12L CCNK EP300 ARID2 KMT2D QRICH1

4.69e-06464107HP:0011339
HumanPhenoHigh, narrow palate

MED12L FOXP2 EP300 ARID2 KMT2D

5.63e-06156105HP:0002705
HumanPhenoDiagnostic behavioral phenotype

MBD5 MED12L FOXP2 CCNK EP300 ARID2 KMT2D QRICH1

7.07e-06747108HP:0025783
HumanPhenoLow-set ears

MBD5 FOXP2 CCNK HS6ST2 EP300 ARID2 KMT2D QRICH1

8.16e-06761108HP:0000369
HumanPhenoDelayed speech and language development

MBD5 MED12L FOXP2 CCNK HS6ST2 EP300 ARID2 KMT2D QRICH1

9.63e-061123109HP:0000750
HumanPhenoLanguage impairment

MBD5 MED12L FOXP2 CCNK HS6ST2 EP300 ARID2 KMT2D QRICH1

1.47e-051178109HP:0002463
HumanPhenoShort columella

MBD5 EP300 KMT2D

1.94e-0529103HP:0002000
HumanPhenoClinodactyly

MBD5 FOXP2 CCNK EP300 ARID2 KMT2D QRICH1

1.97e-05574107HP:0030084
HumanPhenoNarrow palate

MED12L FOXP2 EP300 ARID2 KMT2D

2.00e-05202105HP:0000189
HumanPhenoAbnormality of globe location or size

MBD5 MED12L FOXP2 CCNK HS6ST2 EP300 NOTCH1 KMT2D QRICH1

2.40e-051246109HP:0000489
HumanPhenoAbnormal lip morphology

MBD5 MED12L FOXP2 CCNK HS6ST2 EP300 ARID2 KMT2D QRICH1

2.45e-051249109HP:0000159
HumanPhenoAbnormality of the palpebral fissures

MED12L FOXP2 CCNK HS6ST2 EP300 ARID2 KMT2D QRICH1

2.50e-05880108HP:0008050
HumanPhenoAbnormal nasal tip morphology

MBD5 MED12L CCNK ARID2 KMT2D QRICH1

2.94e-05386106HP:0000436
HumanPhenoAbnormal external nose morphology

MBD5 MED12L FOXP2 CCNK EP300 ARID2 KMT2D QRICH1

3.40e-05916108HP:0010938
HumanPhenoProminent nose

MBD5 FOXP2 EP300 QRICH1

3.91e-05110104HP:0000448
HumanPhenoAbnormal location of ears

MBD5 FOXP2 CCNK HS6ST2 EP300 ARID2 KMT2D QRICH1

4.31e-05945108HP:0000357
HumanPhenoAbnormal lower lip morphology

MBD5 MED12L ARID2 KMT2D QRICH1

4.81e-05242105HP:0000178
HumanPhenoAbnormality of mouth size

MBD5 MED12L FOXP2 EP300 ARID2 QRICH1

5.12e-05425106HP:0011337
HumanPhenoAbnormal upper lip morphology

MBD5 MED12L FOXP2 CCNK EP300 ARID2 KMT2D QRICH1

5.69e-05980108HP:0000177
HumanPhenoAbnormal eyebrow morphology

MBD5 MED12L FOXP2 CCNK EP300 ARID2 KMT2D

5.76e-05674107HP:0000534
HumanPhenoAbnormal finger morphology

MBD5 MED12L FOXP2 CCNK EP300 ARID2 NOTCH1 KMT2D QRICH1

6.03e-051385109HP:0001167
HumanPhenoPostnatal growth retardation

MBD5 FOXP2 EP300 ARID2 KMT2D

6.55e-05258105HP:0008897
HumanPhenoAbnormal eyelid morphology

MBD5 MED12L FOXP2 CCNK HS6ST2 EP300 ARID2 KMT2D QRICH1

6.95e-051408109HP:0000492
HumanPhenoFinger clinodactyly

MBD5 FOXP2 CCNK EP300 KMT2D QRICH1

7.28e-05452106HP:0040019
HumanPhenoMotor delay

MBD5 MED12L CCNK HS6ST2 EP300 ARID2 KMT2D QRICH1

7.60e-051018108HP:0001270
HumanPhenoAbnormality of the philtrum

MED12L FOXP2 CCNK EP300 ARID2 KMT2D QRICH1

9.42e-05726107HP:0000288
HumanPhenoHypoplastic left heart

EP300 NOTCH1 KMT2D

9.58e-0549103HP:0004383
HumanPhenoCongenital malformation of the left heart

EP300 NOTCH1 KMT2D

1.08e-0451103HP:0045017
HumanPhenoAbnormal hand morphology

MBD5 FOXP2 CCNK EP300 ARID2 NOTCH1 KMT2D QRICH1

1.21e-041082108HP:0005922
HumanPhenoAbnormality of the hairline

MBD5 CCNK EP300 ARID2 KMT2D

1.23e-04294105HP:0009553
HumanPhenoPilomatrixoma

EP300 KMT2D

1.24e-049102HP:0030434
HumanPhenoHypoplastic heart

EP300 NOTCH1 KMT2D

1.28e-0454103HP:0001961
HumanPhenoAbnormal size of the palpebral fissures

FOXP2 CCNK EP300 ARID2 KMT2D

1.31e-04298105HP:0200007
HumanPhenoAbnormal 5th finger morphology

MBD5 CCNK EP300 ARID2 KMT2D QRICH1

1.43e-04509106HP:0004207
HumanPhenoGastroesophageal reflux

MBD5 MED12L FOXP2 EP300 ARID2 KMT2D

1.56e-04517106HP:0002020
HumanPhenoAbnormality of globe location

MBD5 MED12L FOXP2 CCNK HS6ST2 EP300 KMT2D QRICH1

1.59e-041122108HP:0100886
HumanPhenoAbnormality of calvarial morphology

MBD5 MED12L FOXP2 HS6ST2 EP300 ARID2 NOTCH1 KMT2D

1.72e-041134108HP:0002648
HumanPhenoCongenital malformation of the great arteries

FOXP2 EP300 ARID2 NOTCH1 KMT2D QRICH1

1.78e-04529106HP:0011603
HumanPhenoDeviation of finger

MBD5 FOXP2 CCNK EP300 KMT2D QRICH1

1.93e-04537106HP:0004097
HumanPhenoShort finger

MBD5 EP300 ARID2 NOTCH1 KMT2D

1.98e-04325105HP:0009381
HumanPhenoCongenital abnormal hair pattern

MBD5 CCNK EP300 ARID2 KMT2D

2.04e-04327105HP:0011361
HumanPhenoFeeding difficulties

MBD5 MED12L FOXP2 HS6ST2 EP300 ARID2 KMT2D QRICH1

2.15e-041168108HP:0011968
HumanPhenoHypertelorism

MBD5 MED12L FOXP2 CCNK EP300 KMT2D QRICH1

2.27e-04830107HP:0000316
HumanPhenoDeviation of the hand or of fingers of the hand

MBD5 FOXP2 CCNK EP300 KMT2D QRICH1

2.55e-04564106HP:0009484
HumanPhenoCupped ear

MBD5 KMT2D QRICH1

2.67e-0469103HP:0000378
HumanPhenoDownturned corners of mouth

MBD5 MED12L HS6ST2 KMT2D

2.80e-04182104HP:0002714
HumanPhenoAplasia/Hypoplasia of fingers

MBD5 EP300 ARID2 NOTCH1 KMT2D

3.47e-04366105HP:0006265
HumanPhenoAbnormal calvaria morphology

MBD5 MED12L FOXP2 HS6ST2 EP300 ARID2 NOTCH1 KMT2D

3.65e-041254108HP:0002683
HumanPhenoBulbous nose

MBD5 MED12L KMT2D QRICH1

4.10e-04201104HP:0000414
HumanPhenoAbnormal fingertip morphology

MED12L FOXP2 EP300 KMT2D

4.26e-04203104HP:0001211
HumanPhenoPremature thelarche

EP300 KMT2D

4.64e-0417102HP:0010314
HumanPhenoProminent eyelashes

ARID2 KMT2D

4.64e-0417102HP:0011231
HumanPhenoAbnormal pinna morphology

MBD5 FOXP2 CCNK HS6ST2 EP300 ARID2 KMT2D QRICH1

4.75e-041299108HP:0000377
HumanPhenoSkin appendage neoplasm

EP300 KMT2D

5.22e-0418102HP:0012842
HumanPhenoHirsutism

MBD5 EP300 ARID2 KMT2D

5.40e-04216104HP:0001007
HumanPhenoAplasia/Hypoplasia of the ear

MBD5 FOXP2 HS6ST2 KMT2D

5.69e-04219104HP:0008771
HumanPhenoMacrostomia

MBD5 FOXP2 ARID2 QRICH1

5.79e-04220104HP:0000181
HumanPhenoWide mouth

MBD5 FOXP2 ARID2 QRICH1

5.79e-04220104HP:0000154
HumanPhenoRecurrent ear infections

MBD5 FOXP2

5.83e-0419102HP:0410018
HumanPhenoAbnormality of the outer ear

MBD5 FOXP2 CCNK HS6ST2 EP300 ARID2 KMT2D QRICH1

5.89e-041337108HP:0000356
HumanPhenoClinodactyly of the 5th finger

MBD5 CCNK EP300 KMT2D QRICH1

6.62e-04420105HP:0004209
HumanPhenoClinodactyly of hands

MBD5 CCNK EP300 KMT2D QRICH1

6.69e-04421105HP:0001157
HumanPhenoDeviation of the 5th finger

MBD5 CCNK EP300 KMT2D QRICH1

6.69e-04421105HP:0009179
HumanPhenoDelayed early-childhood social milestone development

FOXP2 CCNK

7.14e-0421102HP:0012434
HumanPhenoAbnormal columella morphology

MBD5 EP300 KMT2D

7.29e-0497103HP:0009929
HumanPhenoBrachydactyly (hand)

MBD5 EP300 ARID2 NOTCH1 KMT2D

7.38e-04430105HP:0100667
HumanPhenoAbnormality of the scalp hair

MBD5 CCNK EP300 ARID2 KMT2D

7.62e-04433105HP:0100037
HumanPhenoRadial deviation of finger

MBD5 CCNK EP300 KMT2D QRICH1

8.93e-04448105HP:0009466
HumanPhenoAbnormal scalp morphology

MBD5 CCNK EP300 ARID2 KMT2D

9.12e-04450105HP:0001965
HumanPhenoAbnormal hair morphology

MBD5 MED12L FOXP2 CCNK EP300 ARID2 NOTCH1 KMT2D

9.38e-041424108HP:0001595
HumanPhenoRadial deviation of the hand or of fingers of the hand

MBD5 CCNK EP300 KMT2D QRICH1

9.69e-04456105HP:0009485
HumanPhenoAbnormal aortic arch morphology

EP300 NOTCH1 KMT2D

1.03e-03109103HP:0012303
HumanPhenoComplex cardiac malformations

ARID2 NOTCH1 KMT2D QRICH1

1.04e-03257104HP:0002565
HumanPhenoLarge forehead

HS6ST2 ARID2

1.10e-0326102HP:0002003
HumanPhenoAbnormal semicircular canal morphology

FOXP2 KMT2D

1.10e-0326102HP:0011380
HumanPhenoAbnormal morphology of the great vessels

FOXP2 EP300 ARID2 NOTCH1 KMT2D QRICH1

1.11e-03736106HP:0030962
HumanPhenoPosteriorly rotated ears

CCNK HS6ST2 EP300 ARID2 KMT2D

1.11e-03470105HP:0000358
HumanPhenoAbnormal nasal dorsum morphology

MBD5 FOXP2 EP300 KMT2D

1.12e-03262104HP:0011119
HumanPhenoFrontal bossing

MBD5 MED12L HS6ST2 EP300 ARID2 KMT2D

1.13e-03738106HP:0002007
HumanPhenoSlanting of the palpebral fissure

MED12L HS6ST2 EP300 ARID2 KMT2D QRICH1

1.14e-03739106HP:0200006
HumanPhenoAortic valve stenosis

EP300 NOTCH1 KMT2D

1.14e-03113103HP:0001650
HumanPhenoAbnormal shape of the frontal region

MBD5 MED12L HS6ST2 EP300 ARID2 KMT2D

1.16e-03741106HP:0011218
HumanPhenoAbnormal frontal bone morphology

MBD5 MED12L HS6ST2 EP300 ARID2 KMT2D

1.16e-03742106HP:0430000
HumanPhenoAbnormal stomach morphology

MBD5 MED12L FOXP2 EP300 ARID2 KMT2D

1.16e-03742106HP:0002577
HumanPhenoAbnormal nasal septum morphology

MBD5 EP300 KMT2D

1.20e-03115103HP:0000419
HumanPhenoAbnormal esophagus morphology

MBD5 MED12L FOXP2 EP300 ARID2 NOTCH1 KMT2D

1.22e-031078107HP:0002031
HumanPhenoLow posterior hairline

MBD5 EP300 KMT2D

1.26e-03117103HP:0002162
HumanPhenoAbnormality of the posterior hairline

MBD5 EP300 KMT2D

1.26e-03117103HP:0030141
HumanPhenoMitral stenosis

NOTCH1 KMT2D

1.28e-0328102HP:0001718
HumanPhenoBicuspid aortic valve

EP300 NOTCH1 KMT2D

1.32e-03119103HP:0001647
HumanPhenoAbnormal aortic valve cusp morphology

EP300 NOTCH1 KMT2D

1.39e-03121103HP:0031567
HumanPhenoDownslanted palpebral fissures

MED12L HS6ST2 EP300 ARID2 KMT2D

1.44e-03497105HP:0000494
HumanPhenoAbnormal ventriculoarterial connection

ARID2 NOTCH1 KMT2D QRICH1

1.44e-03280104HP:0011563
HumanPhenoMotor stereotypy

MBD5 CCNK EP300 ARID2

1.44e-03280104HP:0000733
MousePhenoabnormal myocardium compact layer morphology

NFAT5 NCOA6 EP300 ARID2 QRICH1

4.17e-0867215MP:0004056
MousePhenoabnormal left-right axis symmetry of the somites

SUPT20HL1 NOTCH1 SUPT20H

1.63e-078213MP:0005224
MousePhenoheart hypoplasia

MIDEAS NCOA6 EP300 NOTCH1

1.51e-05103214MP:0002740
MousePhenoabnormal vitelline vasculature morphology

SUPT20HL1 NCOA6 EP300 NOTCH1 SUPT20H

2.10e-05235215MP:0003229
MousePhenoabnormal myocardium layer morphology

NFAT5 NCOA6 EP300 ARID2 NOTCH1 QRICH1

2.42e-05414216MP:0005329
MousePhenoabnormal heart layer morphology

NFAT5 NCOA6 EP300 ARID2 NOTCH1 QRICH1

2.70e-05422216MP:0010545
MousePhenoincomplete somite formation

SUPT20HL1 EP300 SUPT20H

3.72e-0544213MP:0001689
MousePhenothin myocardium compact layer

NCOA6 EP300 ARID2

4.25e-0546213MP:0004057
MousePhenothin ventricular wall

NFAT5 NCOR2 NCOA6 EP300

4.78e-05138214MP:0000280
MousePhenoabnormal fetal cardiomyocyte proliferation

NFAT5 NCOA6 ARID2

4.84e-0548213MP:0003567
MousePhenoabnormal myocardial trabeculae morphology

NFAT5 NCOA6 EP300 NOTCH1

5.64e-05144214MP:0002189
MousePhenoabnormal cardiac muscle tissue morphology

NFAT5 NCOA6 EP300 ARID2 NOTCH1 QRICH1

6.16e-05489216MP:0010630
MousePhenoabnormal fetal cardiomyocyte physiology

NFAT5 NCOA6 ARID2

7.29e-0555213MP:0011390
MousePhenocraniofacial phenotype

MBD5 FOXP2 NCOR2 NCOA6 EP300 NOTCH1 KMT2D QRICH1 JHY

8.10e-051372219MP:0005382
MousePhenoabnormal craniofacial morphology

MBD5 FOXP2 NCOR2 NCOA6 EP300 NOTCH1 KMT2D QRICH1 JHY

8.10e-051372219MP:0000428
MousePhenoabnormal gastrulation movements

SUPT20HL1 SUPT20H

9.60e-0510212MP:0002174
MousePhenoabnormal heart ventricle morphology

NFAT5 NCOR2 NCOA6 EP300 ARID2 NOTCH1 QRICH1

1.06e-04793217MP:0005294
MousePhenoabnormal vascular development

SUPT20HL1 NCOA6 EP300 ARID2 NOTCH1 SUPT20H

1.09e-04542216MP:0000259
MousePhenoabnormal cardiovascular development

SUPT20HL1 NCOR2 NCOA6 EP300 ARID2 NOTCH1 SUPT20H

1.14e-04802217MP:0002925
MousePhenoabnormal left-right axis patterning

SUPT20HL1 NOTCH1 SUPT20H

1.32e-0467213MP:0001706
MousePhenoventricle myocardium hypoplasia

NCOA6 EP300 NOTCH1

1.56e-0471213MP:0010502
MousePhenoprenatal growth retardation

MIDEAS SUPT20HL1 NCOR2 NCOA6 EP300 NOTCH1 SUPT20H

1.88e-04869217MP:0010865
MousePhenoabnormal trabecula carnea morphology

NCOA6 EP300 NOTCH1

2.07e-0478213MP:0004067
MousePhenomyocardium hypoplasia

NCOA6 EP300 NOTCH1

2.76e-0486213MP:0010500
MousePhenoabnormal epicardium morphology

NCOA6 EP300

2.88e-0417212MP:0003057
MousePhenoabnormal somite development

SUPT20HL1 EP300 NOTCH1 SUPT20H

3.00e-04222214MP:0001688
MousePhenoabnormal pericardium morphology

MIDEAS NCOA6 EP300 NOTCH1

3.15e-04225214MP:0000288
MousePhenodecreased fetal cardiomyocyte proliferation

NCOA6 ARID2

3.24e-0418212MP:0011395
MousePhenoabnormal heart ventricle wall thickness

NFAT5 NCOR2 NCOA6 EP300

3.26e-04227214MP:0020135
MousePhenoabnormal hippocampus layer morphology

CPEB3 SUSD4 KMT2D

3.37e-0492213MP:0000813
MousePhenolethality throughout fetal growth and development

NFAT5 MIDEAS NCOR2 NCOA6 EP300

3.84e-04435215MP:0006208
MousePhenoventricular hypoplasia

NCOA6 EP300 NOTCH1

4.18e-0499213MP:0000279
MousePhenoimpaired somite development

SUPT20HL1 EP300 SUPT20H

4.83e-04104213MP:0009768
MousePhenoventricular septal defect

NCOR2 EP300 ARID2 QRICH1

5.53e-04261214MP:0010402
MousePhenolethality throughout fetal growth and development, complete penetrance

NFAT5 MIDEAS NCOR2 NCOA6

5.69e-04263214MP:0011099
MousePhenoabnormal ventricle myocardium morphology

NCOA6 EP300 NOTCH1

6.64e-04116213MP:0010499
MousePhenoabnormal forebrain morphology

CPEB3 MBD5 NCOR2 NCOA6 SUSD4 KMT2D JHY

6.83e-041072217MP:0000783
MousePhenoembryonic growth retardation

SUPT20HL1 NCOR2 NCOA6 EP300 NOTCH1 SUPT20H

6.94e-04763216MP:0003984
MousePhenoabnormal heart ventricle wall morphology

NFAT5 NCOR2 NCOA6 EP300

8.87e-04296214MP:0031532
MousePhenoabnormal telencephalon morphology

CPEB3 NCOR2 NCOA6 SUSD4 KMT2D JHY

9.63e-04812216MP:0000787
MousePhenoabnormal rostral-caudal axis patterning

SUPT20HL1 NOTCH1 SUPT20H

9.66e-04132213MP:0005221
MousePhenosmall heart

MIDEAS NCOA6 EP300 NOTCH1

1.20e-03321214MP:0002188
MousePhenoabnormal interventricular septum morphology

NCOR2 EP300 ARID2 QRICH1

1.52e-03342214MP:0000281
MousePhenoabnormal paraxial mesoderm morphology

SUPT20HL1 SUPT20H

1.62e-0340212MP:0008029
MousePhenoembryo tissue necrosis

SUPT20HL1 SUPT20H

1.62e-0340212MP:0013241
MousePhenodisorganized myocardium

NCOA6 NOTCH1

1.62e-0340212MP:0002190
MousePhenoabnormal placenta development

SUPT20HL1 NCOA6 SUPT20H

1.68e-03160213MP:0001712
MousePhenoabnormal extraembryonic tissue morphology

SUPT20HL1 NCOR2 NCOA6 EP300 NOTCH1 SUPT20H

1.72e-03908216MP:0002086
MousePhenoabnormal nervous system development

FOXP2 SUPT20HL1 NCOA6 EP300 NOTCH1 JHY SUPT20H

1.76e-031257217MP:0003861
MousePhenoabnormal heart valve morphology

EP300 ARID2 NOTCH1

1.77e-03163213MP:0000285
MousePhenolethality during fetal growth through weaning, complete penetrance

MBD5 FOXP2 NFAT5 MIDEAS NCOR2 NCOA6 EP300

1.86e-031269217MP:0011111
MousePhenoincreased megakaryocyte cell number

NCOR2 EP300

2.05e-0345212MP:0008254
MousePhenoabnormal heart development

NCOR2 NCOA6 EP300 NOTCH1

2.06e-03372214MP:0000267
MousePhenotrabecula carnea hypoplasia

NCOA6 NOTCH1

2.14e-0346212MP:0000295
MousePhenoabnormal limbic system morphology

CPEB3 NCOA6 SUSD4 KMT2D

2.19e-03378214MP:0004166
MousePhenoabnormal bile salt homeostasis

NCOA6 KMT2D

2.23e-0347212MP:0005365
MousePhenoabnormal eye pigmentation

SUPT20HL1 NCOA6 SUPT20H

2.32e-03179213MP:0001324
MousePhenoabnormal heart septum morphology

NCOR2 EP300 ARID2 QRICH1

2.40e-03388214MP:0006113
MousePhenoabnormal extracutaneous pigmentation

SUPT20HL1 NCOA6 SUPT20H

2.58e-03186213MP:0009389
MousePhenoincreased insulin sensitivity

MBD5 NCOR2 KMT2D

2.66e-03188213MP:0002891
MousePhenoabnormal placenta vasculature

NCOR2 NCOA6 NOTCH1

2.83e-03192213MP:0003231
MousePhenocaudal body truncation

SUPT20HL1 SUPT20H

2.93e-0354212MP:0004073
MousePhenoabnormal vasculogenesis

EP300 NOTCH1

2.93e-0354212MP:0001622
MousePhenofailure of initiation of embryo turning

SUPT20HL1 SUPT20H

3.15e-0356212MP:0004180
MousePhenoembryonic lethality during organogenesis, complete penetrance

NCOA6 EP300 ARID2 NOTCH1 KMT2D

3.23e-03700215MP:0011098
MousePhenoabnormal hippocampus pyramidal cell morphology

CPEB3 SUSD4

3.26e-0357212MP:0009940
MousePhenokinked neural tube

EP300 NOTCH1

3.26e-0357212MP:0003400
MousePhenoabnormal placenta physiology

SUPT20HL1 NCOA6 SUPT20H

3.36e-03204213MP:0010038
MousePhenomyocardial trabeculae hypoplasia

NCOA6 NOTCH1

3.38e-0358212MP:0010503
DomainSANT_dom

MIDEAS NCOR2

4.23e-0426222IPR017884
DomainSANT

MIDEAS NCOR2

4.91e-0428222PS51293
DomainMyb_DNA-binding

MIDEAS NCOR2

7.70e-0435222PF00249
DomainMYB_LIKE

MIDEAS NCOR2

9.08e-0438222PS50090
DomainSANT

MIDEAS NCOR2

1.57e-0350222SM00717
DomainSANT/Myb

MIDEAS NCOR2

1.69e-0352222IPR001005
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

MAML3 EP300 NOTCH1

1.43e-0710163MM15535
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

NCOR2 MAML3 EP300 NOTCH1

1.92e-0747164M7946
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NCOR2 MAML3 EP300 NOTCH1

2.09e-0748164M611
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

MAML3 EP300 NOTCH1

4.33e-0714163M27808
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

NCOR2 MAML3 EP300 NOTCH1

4.52e-0758164M29616
PathwayWP_NOTCH_SIGNALING_WP61

NCOR2 MAML3 EP300 NOTCH1

5.55e-0761164M39540
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

MAML3 EP300 NOTCH1

6.66e-0716163M27121
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

FOXP2 MAML3 EP300 NOTCH1

7.19e-0765164M39682
PathwayREACTOME_SIGNALING_BY_NOTCH1

MAML3 EP300 NOTCH1

9.69e-0718163MM14775
PathwayREACTOME_SIGNALING_BY_NOTCH1

NCOR2 MAML3 EP300 NOTCH1

1.21e-0674164M616
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML3 EP300 NOTCH1

1.35e-0620163M27881
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

NCOR2 MAML3 EP300 NOTCH1

1.84e-0682164MM15922
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

MED15 NCOR2 NCOA6 EP300

2.02e-0684164M1008
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NCOR2 MAML3 NOTCH1

2.10e-0623163MM14954
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML3 EP300 NOTCH1

2.72e-0625163M27880
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NCOR2 MAML3 NOTCH1

3.86e-0628163M6177
PathwayREACTOME_ADIPOGENESIS

MED15 NCOR2 NCOA6 EP300

5.94e-06110164M48259
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

MED15 NCOR2 NCOA6 EP300

7.86e-06118164M27316
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

NCOR2 EP300 ARID2 KMT2D SUPT20H

9.46e-06272165M29619
PathwayREACTOME_SIGNALING_BY_NOTCH

MAML3 EP300 NOTCH1

1.07e-0539163MM14604
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

MAML3 EP300 NOTCH1

1.34e-0542163M17541
PathwayWP_NOTCH_SIGNALING_WP268

NCOR2 MAML3 NOTCH1

1.65e-0545163M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

NCOR2 MAML3 NOTCH1

1.77e-0546163MM15971
PathwayPID_HES_HEY_PATHWAY

NCOR2 EP300 NOTCH1

2.01e-0548163M288
PathwayREACTOME_SIGNALING_BY_NOTCH3

MAML3 EP300 NOTCH1

2.14e-0549163M618
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER

NCOR2 CCNK EP300

2.42e-0551163M665
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

EP300 NOTCH1

3.37e-058162M48024
PathwayPID_NOTCH_PATHWAY

NCOR2 EP300 NOTCH1

3.75e-0559163M17
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

MED15 NCOR2 CCNK MAML3 EP300 ARID2 NOTCH1 KMT2D

5.37e-051387168M734
PathwayREACTOME_FORMATION_OF_PARAXIAL_MESODERM

MAML3 EP300 NOTCH1

6.00e-0569163M46439
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

EP300 NOTCH1

6.60e-0511162M48021
PathwayREACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS

NCOR2 NCOA6 EP300 NOTCH1

7.57e-05210164M41836
PathwayREACTOME_NOTCH2_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML3 EP300

7.92e-0512162M27159
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

MAML3 NOTCH1

7.92e-0512162M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

MAML3 NOTCH1

7.92e-0512162M47533
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3

MAML3 EP300 NOTCH1

8.02e-0576163MM15520
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

MAML3 NOTCH1

9.35e-0513162M47534
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

NCOR2 EP300

9.35e-0513162MM15622
PathwayREACTOME_SIGNALING_BY_NOTCH4

MAML3 EP300 NOTCH1

1.01e-0482163M594
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

NCOR2 CCNK MAML3 EP300 NOTCH1 KMT2D

1.28e-04768166MM14851
PathwayREACTOME_SIGNALING_BY_NOTCH

NCOR2 MAML3 EP300 NOTCH1

1.40e-04246164M10189
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

NCOR2 CCNK EP300

1.51e-0494163M1041
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3

MAML3 EP300 NOTCH1

1.61e-0496163M27784
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

NCOA6 EP300

1.83e-0418162M26942
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

MAML3 EP300 NOTCH1

3.03e-04119163M607
PathwayREACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

NCOA6 EP300 KMT2D

3.26e-04122163M29689
PathwayREACTOME_GASTRULATION

MAML3 EP300 NOTCH1

3.84e-04129163M46433
PathwayBIOCARTA_CARM_ER_PATHWAY

NCOR2 EP300

3.86e-0426162M2499
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

EP300 KMT2D

3.86e-0426162MM14793
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

MAML3 NOTCH1

4.17e-0427162M39545
PathwayWP_KLEEFSTRA_SYNDROME

MBD5 NCOA6

4.82e-0429162M48076
PathwayPID_RETINOIC_ACID_PATHWAY

NCOR2 EP300

5.16e-0430162M207
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

MED15 NCOR2 MAML3 NCOA6 EP300 NOTCH1 KMT2D

5.50e-041432167M509
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

NCOR2 CCNK MAML3 EP300 NOTCH1 KMT2D

6.08e-041022166MM15436
PathwayREACTOME_SIGNALING_BY_NOTCH2

MAML3 EP300

6.25e-0433162M604
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

NCOR2 CCNK EP300

7.34e-04161163M27871
PathwayREACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION

CCNK EP300

7.44e-0436162M633
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

EP300 ARID2

7.86e-0437162M27797
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

NCOR2 EP300

7.86e-0437162M29790
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER

NCOR2 CCNK

9.65e-0441162MM14876
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

NCOA6 KMT2D

1.01e-0342162M48018
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

NCOR2 EP300

1.11e-0344162M27295
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

EP300 KMT2D

1.11e-0344162MM15527
PathwayWP_ARYL_HYDROCARBON_RECEPTOR_PATHWAY_WP2586

NCOR2 EP300

1.21e-0346162M39661
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

NCOR2 EP300

1.27e-0347162M29777
PathwayREACTOME_HEME_SIGNALING

NCOA6 EP300

1.38e-0349162M41832
PathwayREACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

NCOR2 MAML3 EP300 NOTCH1

1.54e-03464164M27547
PathwayBIOCARTA_PPARA_PATHWAY

NCOR2 EP300

1.55e-0352162M2404
PathwayREACTOME_CYTOPROTECTION_BY_HMOX1

NCOR2 NCOA6

2.06e-0360162M41830
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

EP300 ARID2 KMT2D

2.23e-03237163M27786
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2

NCOR2 NOTCH1

2.27e-0363162M27862
PathwayPID_ERA_GENOMIC_PATHWAY

NCOR2 EP300

2.34e-0364162M200
PathwayPID_HDAC_CLASSI_PATHWAY

NCOR2 EP300

2.48e-0366162M101
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

NCOA6 EP300 KMT2D

2.72e-03254163M27131
PathwayREACTOME_CIRCADIAN_CLOCK

NCOA6 EP300

2.79e-0370162M938
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

NCOR2 CCNK

3.36e-0377162MM14670
PathwayPID_SMAD2_3NUCLEAR_PATHWAY

MED15 EP300

3.80e-0382162M2
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

EP300 NOTCH1 KMT2D

4.39e-03301163MM15983
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

EP300 KMT2D

4.66e-0391162M27101
PathwayWP_ANDROGEN_RECEPTOR_SIGNALING

NCOR2 EP300

4.66e-0391162M39700
PathwayREACTOME_NUCLEAR_EVENTS_MEDIATED_BY_NFE2L2

EP300 NOTCH1

5.18e-0396162M45026
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

EP300 KMT2D

5.18e-0396162M27792
PathwayREACTOME_RSV_HOST_INTERACTIONS

MED15 EP300

5.39e-0398162M48247
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

NCOR2 CCNK

7.72e-03118162MM15588
Pubmed

cDNAs with long CAG trinucleotide repeats from human brain.

MED15 FOXP2 NCOR2 MAML3 KMT2D

2.65e-12232359225980
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

MED15 MIDEAS HELZ NCOR2 MAML3 NCOA6 EP300 KMT2D QRICH1

7.50e-1245723932344865
Pubmed

Interaction network of human early embryonic transcription factors.

MED15 FOXP2 MIDEAS NCOR2 NCOA6 EP300 ARID2 KMT2D

4.27e-1135123838297188
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

MIDEAS NCOR2 NCOA6 EP300 KMT2D

2.23e-098323528794006
Pubmed

Human transcription factor protein interaction networks.

MED15 FOXP2 MIDEAS HELZ NCOR2 NCOA6 EP300 ARID2 KMT2D SUPT20H

9.32e-091429231035140242
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

MED15 MIDEAS NCOR2 CCNK NCOA6 EP300 ARID2 KMT2D QRICH1

1.72e-08110323934189442
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

MED15 MIDEAS CCNK NCOA6 EP300 ARID2 KMT2D

4.63e-0854923738280479
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

MED15 MIDEAS NCOR2 CCNK EP300

4.71e-0815223538360978
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

MED15 NCOR2 MAML3 NCOA6 EP300 ARID2 KMT2D

1.28e-0763823731182584
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

MED15 NCOR2 EP300 ARID2 KMT2D SUPT20H

1.85e-0739823635016035
Pubmed

T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.

NCOR2 NCOA6 EP300

2.86e-072023311877444
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

MIDEAS NCOR2 EP300 ARID2 KMT2D

2.97e-0722023535785414
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

NCOR2 NCOA6 EP300

3.33e-072123319596656
Pubmed

A human MAP kinase interactome.

MBD5 MIDEAS HELZ EP300 ARID2 SUPT20H

5.96e-0748623620936779
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

MED15 MIDEAS CCNK NCOA6 KMT2D

7.86e-0726823533640491
Pubmed

Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas.

NOTCH1 KMT2D

1.25e-06323227566587
Pubmed

The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression.

EP300 KMT2D

1.25e-06323237410700
Pubmed

The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5.

SUPT20HL1 SUPT20H

1.25e-06323224220028
Pubmed

p300 acts as a transcriptional coactivator for mammalian Notch-1.

EP300 NOTCH1

1.25e-06323211604511
Pubmed

A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription.

EP300 KMT2D

1.25e-06323228732206
Pubmed

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.

EP300 KMT2D

2.51e-06423228398509
Pubmed

Direct association between the CREB-binding protein (CBP) and nuclear receptor corepressor (N-CoR).

NCOR2 EP300

2.51e-06423217073437
Pubmed

Transcriptional coactivator PRIP, the peroxisome proliferator-activated receptor gamma (PPARgamma)-interacting protein, is required for PPARgamma-mediated adipogenesis.

NCOA6 EP300

2.51e-06423212754253
Pubmed

Wnt5a controls Notch1 signaling through CaMKII-mediated degradation of the SMRT corepressor protein.

NCOR2 NOTCH1

2.51e-06423222888005
Pubmed

LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding.

NFAT5 EP300

2.51e-06423227118681
Pubmed

SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function.

NCOR2 NOTCH1

2.51e-06423210713164
Pubmed

p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro.

EP300 NOTCH1

2.51e-06423212391150
Pubmed

Ubiquitination of Notch1 is regulated by MAML1-mediated p300 acetylation of Notch1.

EP300 NOTCH1

2.51e-06423222100894
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

NCOA6 EP300 ARID2 KMT2D

3.31e-0615723430186101
Pubmed

Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor.

EP300 NOTCH1

4.18e-06523211564735
Pubmed

Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway.

NCOR2 NOTCH1

4.18e-06523221475249
Pubmed

Interaction of PIMT with transcriptional coactivators CBP, p300, and PBP differential role in transcriptional regulation.

NCOA6 EP300

4.18e-06523211912212
Pubmed

Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300.

NCOR2 EP300

4.18e-06523214985122
Pubmed

The origin of the ankyrin repeat region in Notch intracellular domains is critical for regulation of HES promoter activity.

NCOR2 NOTCH1

6.26e-06623211404076
Pubmed

Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch.

NCOR2 EP300

6.26e-06623226859354
Pubmed

Identification and characterization of RRM-containing coactivator activator (CoAA) as TRBP-interacting protein, and its splice variant as a coactivator modulator (CoAM).

NCOA6 EP300

6.26e-06623211443112
Pubmed

Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells.

EP300 NOTCH1

6.26e-06623219838210
Pubmed

Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.

NCOA6 KMT2D

6.26e-06623217021013
Pubmed

LPCAT3 Is Transcriptionally Regulated by YAP/ZEB/EP300 and Collaborates with ACSL4 and YAP to Determine Ferroptosis Sensitivity.

EP300 KMT2D

8.77e-06723237166352
Pubmed

ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.

NCOA6 KMT2D

8.77e-06723219556342
Pubmed

PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.

MED15 NCOA6 KMT2D

1.07e-056523322496869
Pubmed

Crosstalk between Nodal/activin and MAPK p38 signaling is essential for anterior-posterior axis specification.

SUPT20HL1 SUPT20H

1.17e-05823221802298
Pubmed

Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2.

NCOR2 EP300

1.17e-05823217158926
Pubmed

Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression.

NCOR2 EP300

1.17e-05823220935208
Pubmed

Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.

NCOA6 KMT2D

1.17e-05823217178841
Pubmed

Aberrant association of promyelocytic leukemia protein-retinoic acid receptor-alpha with coactivators contributes to its ability to regulate gene expression.

NCOR2 EP300

1.17e-05823217475621
Pubmed

Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator.

NCOA6 EP300

1.17e-05823210823961
Pubmed

Nuclear monomeric integrin αv in cancer cells is a coactivator regulated by thyroid hormone.

NCOR2 EP300

1.50e-05923223640055
Pubmed

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

MAML3 NOTCH1

1.50e-05923212370315
Pubmed

Role of promyelocytic leukemia zinc finger (PLZF) in cell proliferation and cyclin-dependent kinase inhibitor 1A (p21WAF/CDKN1A) gene repression.

NCOR2 EP300

1.50e-05923224821727
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FOXP2 NCOR2 EP300 NOTCH1 KMT2D QRICH1

1.55e-0585723625609649
Pubmed

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.

NCOR2 NCOA6 KMT2D

1.86e-057823328611094
Pubmed

Natural helix 9 mutants of PPARγ differently affect its transcriptional activity.

NCOR2 EP300

1.88e-051023230595551
Pubmed

Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells.

NCOR2 EP300

1.88e-051023212738788
Pubmed

HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia.

MED15 EP300

1.88e-051023223746844
Pubmed

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover.

EP300 NOTCH1

2.29e-051123215546612
Pubmed

Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes.

NCOR2 EP300

2.29e-051123215681609
Pubmed

Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects.

SUPT20HL1 SUPT20H

2.29e-051123224051374
Pubmed

Activator-Mediator binding regulates Mediator-cofactor interactions.

MED15 EP300

2.29e-051123220534441
Pubmed

Two distinct nuclear receptor-interaction domains and CREB-binding protein-dependent transactivation function of activating signal cointegrator-2.

NCOR2 NCOA6

2.75e-051223211158331
Pubmed

Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.

NCOA6 EP300

2.75e-051223212189208
Pubmed

SMRT derepression by the IkappaB kinase alpha: a prerequisite to NF-kappaB transcription and survival.

NCOR2 EP300

3.25e-051323215494311
Pubmed

Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.

NCOA6 KMT2D

3.25e-051323217761849
Pubmed

A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.

FOXP2 EP300

3.25e-051323222936669
Pubmed

Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.

NCOA6 KMT2D

3.79e-051423212482968
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

MED15 NCOR2 CCNK EP300 QRICH1 SUPT20H

3.99e-05101423632416067
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

MED15 CCNK NOTCH1 QRICH1 SUPT20H

4.16e-0560823516713569
Pubmed

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300.

NCOR2 EP300

4.37e-05152329267036
Pubmed

The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex.

NCOA6 KMT2D

4.37e-051523217925232
Pubmed

SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.

NCOA6 EP300

4.99e-051623223870121
Pubmed

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.

NCOA6 KMT2D

4.99e-051623224368734
Pubmed

MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.

NCOA6 KMT2D

5.66e-051723226180087
Pubmed

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

NCOR2 EP300

5.66e-051723219183483
Pubmed

Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling.

NCOA6 EP300

5.66e-051723228291835
Pubmed

PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.

NCOA6 KMT2D

6.36e-051823217500065
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MBD5 NCOR2 NCOA6 EP300 NOTCH1 KMT2D

6.44e-05110523635748872
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

FOXP2 HELZ NCOR2 EP300 ARID2 SUPT20H

6.80e-05111623631753913
Pubmed

The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program.

MAML3 NOTCH1

7.89e-052023221750544
Pubmed

FBXW7 Triggers Degradation of KMT2D to Favor Growth of Diffuse Large B-cell Lymphoma Cells.

NCOA6 KMT2D

7.89e-052023232350066
Pubmed

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.

NCOA6 KMT2D

7.89e-052023229785026
Pubmed

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.

NCOA6 KMT2D

7.89e-052023219047629
Pubmed

The histone H3-lysine 4-methyltransferase Mll4 regulates the development of growth hormone-releasing hormone-producing neurons in the mouse hypothalamus.

FOXP2 KMT2D

7.89e-052023233431871
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

FOXP2 HELZ EP300 NOTCH1

8.37e-0535823432460013
Pubmed

Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation.

SUPT20HL1 SUPT20H

8.72e-052123223747598
Pubmed

Supt20 is required for development of the axial skeleton.

SUPT20HL1 SUPT20H

8.72e-052123227894818
Pubmed

p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.

SUPT20HL1 SUPT20H

9.59e-052223216751104
Pubmed

Structural basis for activity regulation of MLL family methyltransferases.

NCOA6 KMT2D

9.59e-052223226886794
Pubmed

A novel function for Foxm1 in interkinetic nuclear migration in the developing telencephalon and anxiety-related behavior.

FOXP2 NOTCH1

9.59e-052223224453338
Pubmed

Composite co-activator ARC mediates chromatin-directed transcriptional activation.

MED15 EP300

1.05e-042323210235267
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

HELZ NCOR2 CCNK NCOA6 KMT2D

1.30e-0477423515302935
Pubmed

The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs.

MAML3 NOTCH1

1.35e-042623224391519
Pubmed

Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.

EP300 SUPT20H

1.45e-042723218838386
Pubmed

Reconstruction of phrenic neuron identity in embryonic stem cell-derived motor neurons.

HS6ST2 NOTCH1

1.45e-042723224496616
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

MIDEAS NCOR2 NCOA6 EP300 KMT2D SUPT20H

1.53e-04129423630804502
Pubmed

Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.

FOXP2 NFAT5

1.56e-042823229365100
Pubmed

Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.

FOXP2 EP300

1.56e-042823231600191
Pubmed

Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action.

NCOR2 EP300

1.56e-042823224880616
Pubmed

The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.

SUPT20HL1 SUPT20H

1.56e-042823219114550
Pubmed

Impaired Interneuron Development after Foxg1 Disruption.

FOXP2 NOTCH1

1.68e-042923226620267
Pubmed

SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron.

NCOR2 NOTCH1

1.68e-042923217928865
InteractionFEV interactions

FOXP2 MIDEAS NCOR2 NCOA6 EP300 ARID2 KMT2D SUPT20H

2.62e-11203228int:FEV
InteractionTLE3 interactions

MED15 MIDEAS HELZ NCOR2 EP300 ARID2 NOTCH1 KMT2D QRICH1

1.00e-10376229int:TLE3
InteractionCRX interactions

MED15 FOXP2 MIDEAS NCOR2 EP300 ARID2 KMT2D QRICH1

1.57e-10254228int:CRX
InteractionNUP35 interactions

MED15 MIDEAS HELZ NCOR2 MAML3 NCOA6 EP300 KMT2D QRICH1

2.90e-10424229int:NUP35
InteractionEGR2 interactions

FOXP2 MIDEAS NCOR2 NCOA6 EP300 ARID2 KMT2D

4.29e-10171227int:EGR2
InteractionMED23 interactions

MED12L MED15 CCNK NCOA6 EP300 NOTCH1 SUPT20H

9.29e-09266227int:MED23
InteractionGSC interactions

FOXP2 MIDEAS NCOR2 EP300 KMT2D

3.32e-0887225int:GSC
InteractionSOX17 interactions

MIDEAS NCOR2 NCOA6 ARID2 KMT2D

5.17e-0895225int:SOX17
InteractionGATA2 interactions

MIDEAS NCOR2 NCOA6 EP300 ARID2 KMT2D

5.62e-08199226int:GATA2
InteractionSOX9 interactions

MIDEAS NCOA6 EP300 ARID2 KMT2D

5.74e-0897225int:SOX9
InteractionPAX6 interactions

MIDEAS NCOR2 NCOA6 EP300 ARID2 KMT2D QRICH1

8.30e-08366227int:PAX6
InteractionTBR1 interactions

FOXP2 MIDEAS NCOR2 EP300 KMT2D

1.24e-07113225int:TBR1
InteractionTBXT interactions

MIDEAS NCOR2 NCOA6 EP300 KMT2D

1.41e-07116225int:TBXT
InteractionEYA4 interactions

MED15 MIDEAS HELZ NCOR2 CCNK EP300

1.83e-07243226int:EYA4
InteractionPAX9 interactions

MIDEAS NCOR2 NCOA6 EP300 KMT2D

2.49e-07130225int:PAX9
InteractionHNF4A interactions

MIDEAS NCOR2 NCOA6 EP300 ARID2 KMT2D

3.80e-07275226int:HNF4A
InteractionNCOA6 interactions

MED15 NCOR2 NCOA6 EP300 KMT2D

4.29e-07145225int:NCOA6
InteractionAR interactions

MED12L MED15 MIDEAS NCOR2 CCNK NCOA6 EP300 ARID2 KMT2D

4.55e-07992229int:AR
InteractionTLX3 interactions

MIDEAS NCOR2 NCOA6 EP300 ARID2 KMT2D

5.29e-07291226int:TLX3
InteractionSP7 interactions

MIDEAS NCOR2 NCOA6 EP300 ARID2 KMT2D

6.83e-07304226int:SP7
InteractionFOS interactions

NFAT5 NCOR2 NCOA6 EP300 ARID2 KMT2D

7.95e-07312226int:FOS
InteractionGCM1 interactions

MIDEAS NCOR2 EP300 KMT2D

8.28e-0768224int:GCM1
InteractionTEAD1 interactions

MIDEAS NCOR2 EP300 ARID2 KMT2D

1.12e-06176225int:TEAD1
InteractionALG13 interactions

HELZ NCOR2 CCNK EP300 KMT2D

1.36e-06183225int:ALG13
InteractionLHX3 interactions

MIDEAS NCOR2 ARID2 KMT2D QRICH1

1.43e-06185225int:LHX3
InteractionNFIA interactions

MED15 MIDEAS NCOR2 EP300 KMT2D

1.55e-06188225int:NFIA
InteractionHNF1B interactions

MIDEAS NCOR2 EP300 ARID2 KMT2D

1.63e-06190225int:HNF1B
InteractionSOX7 interactions

NCOR2 EP300 ARID2 KMT2D

1.76e-0682224int:SOX7
InteractionKLF5 interactions

NCOR2 NCOA6 EP300 ARID2 KMT2D

1.86e-06195225int:KLF5
InteractionIRF4 interactions

NCOR2 EP300 ARID2 KMT2D

2.03e-0685224int:IRF4
InteractionSOX10 interactions

NCOR2 EP300 ARID2 KMT2D

2.79e-0692224int:SOX10
InteractionCEBPA interactions

MED15 MIDEAS NCOR2 CCNK NCOA6 EP300 ARID2 KMT2D QRICH1

3.04e-061245229int:CEBPA
InteractionERG interactions

MIDEAS NCOR2 NCOA6 EP300 KMT2D

3.58e-06223225int:ERG
InteractionNFIX interactions

MIDEAS NCOR2 ARID2 KMT2D QRICH1

3.91e-06227225int:NFIX
InteractionKLF3 interactions

MIDEAS NCOR2 EP300 ARID2 KMT2D

3.99e-06228225int:KLF3
InteractionLHX1 interactions

NCOR2 ARID2 KMT2D SUPT20H

4.39e-06103224int:LHX1
InteractionFOXP3 interactions

MED15 FOXP2 NFAT5 MIDEAS HELZ EP300

5.23e-06432226int:FOXP3
InteractionNR1H4 interactions

NCOR2 NCOA6 EP300

5.49e-0632223int:NR1H4
InteractionEN1 interactions

MIDEAS NCOR2 EP300 KMT2D

5.70e-06110224int:EN1
InteractionPAX8 interactions

MIDEAS NCOR2 EP300 KMT2D

5.91e-06111224int:PAX8
InteractionASF1A interactions

NCOR2 NCOA6 EP300 ARID2 KMT2D

6.13e-06249225int:ASF1A
InteractionPAX7 interactions

MIDEAS NCOR2 EP300 KMT2D

9.17e-06124224int:PAX7
InteractionRELA interactions

MED15 NCOR2 NCOA6 EP300 NOTCH1 KMT2D

1.01e-05485226int:RELA
InteractionYAP1 interactions

MED15 NFAT5 MIDEAS CCNK NCOA6 EP300 ARID2 KMT2D

1.19e-051095228int:YAP1
InteractionKLF15 interactions

MED15 NCOR2 EP300 ARID2 KMT2D

1.28e-05290225int:KLF15
InteractionHCFC1 interactions

MBD5 MED15 NCOA6 NOTCH1 KMT2D

1.35e-05293225int:HCFC1
InteractionSOX15 interactions

NCOR2 EP300 ARID2 KMT2D

1.52e-05141224int:SOX15
InteractionPPARG interactions

NCOR2 NCOA6 EP300 ARID2 KMT2D

1.69e-05307225int:PPARG
InteractionELF5 interactions

MIDEAS EP300 ARID2 KMT2D

1.79e-05147224int:ELF5
InteractionNR1I2 interactions

NCOR2 NCOA6 EP300

1.89e-0548223int:NR1I2
InteractionKLF8 interactions

NCOR2 EP300 ARID2 KMT2D SUPT20H

2.36e-05329225int:KLF8
InteractionLHX4 interactions

NCOR2 ARID2 KMT2D QRICH1

2.89e-05166224int:LHX4
InteractionSETD1A interactions

CCNK NCOA6 EP300 KMT2D

3.18e-05170224int:SETD1A
InteractionH3C1 interactions

MBD5 MIDEAS EP300 ARID2 KMT2D JHY SUPT20H

3.30e-05901227int:H3C1
InteractionTLX1 interactions

MIDEAS NCOR2 EP300 KMT2D

3.56e-05175224int:TLX1
InteractionGATA3 interactions

MIDEAS NCOR2 EP300 KMT2D

4.61e-05187224int:GATA3
InteractionMYOD1 interactions

MIDEAS NCOR2 EP300 KMT2D

5.32e-05194224int:MYOD1
InteractionNR3C1 interactions

MED15 NCOR2 MAML3 NCOA6 EP300 ARID2 KMT2D

5.42e-05974227int:NR3C1
InteractionETV4 interactions

NCOR2 EP300 KMT2D

5.65e-0569223int:ETV4
InteractionCTBP1 interactions

MED15 FOXP2 HELZ NCOR2 EP300

6.43e-05406225int:CTBP1
InteractionMAML1 interactions

MAML3 EP300 NOTCH1

6.68e-0573223int:MAML1
InteractionMED1 interactions

MED12L MED15 NCOA6 EP300

6.71e-05206224int:MED1
InteractionWWTR1 interactions

NCOA6 EP300 ARID2 NOTCH1 KMT2D

7.71e-05422225int:WWTR1
InteractionSOX2 interactions

MIDEAS HELZ NCOR2 CCNK NCOA6 EP300 ARID2 KMT2D

7.87e-051422228int:SOX2
InteractionASCL2 interactions

NCOA6 EP300

8.81e-0513222int:ASCL2
InteractionPAX2 interactions

MIDEAS NCOR2 KMT2D

1.05e-0485223int:PAX2
InteractionSMAD1 interactions

MED15 NCOA6 EP300 KMT2D

1.27e-04243224int:SMAD1
InteractionPPARA interactions

NCOR2 NCOA6 EP300

1.33e-0492223int:PPARA
InteractionFOXI1 interactions

NCOR2 EP300 KMT2D

1.33e-0492223int:FOXI1
InteractionHCFC2 interactions

HELZ NCOA6 KMT2D

1.33e-0492223int:HCFC2
InteractionRBPJ interactions

NCOR2 MAML3 EP300 NOTCH1

1.51e-04254224int:RBPJ
InteractionMAML2 interactions

EP300 NOTCH1

1.53e-0417222int:MAML2
InteractionNCOR2 interactions

HELZ NCOR2 NCOA6 EP300

1.75e-04264224int:NCOR2
InteractionMAML3 interactions

MAML3 NOTCH1

2.14e-0420222int:MAML3
InteractionTHRA interactions

NCOR2 NCOA6 EP300

2.32e-04111223int:THRA
InteractionELF4 interactions

ARID2 KMT2D SUPT20H

2.58e-04115223int:ELF4
InteractionUTY interactions

NCOA6 KMT2D

2.84e-0423222int:UTY
InteractionB4GALT2 interactions

HELZ NCOR2 QRICH1

2.85e-04119223int:B4GALT2
InteractionEYA2 interactions

HELZ NCOR2 KMT2D

2.99e-04121223int:EYA2
InteractionETS1 interactions

EP300 ARID2 KMT2D

2.99e-04121223int:ETS1
InteractionNR6A1 interactions

NCOR2 EP300

3.09e-0424222int:NR6A1
InteractionNFKB1 interactions

NCOR2 NCOA6 EP300 NOTCH1

3.11e-04307224int:NFKB1
InteractionVDR interactions

NCOR2 NCOA6 EP300

3.45e-04127223int:VDR
InteractionSMG7 interactions

HELZ NCOR2 NCOA6 KMT2D

3.60e-04319224int:SMG7
InteractionSTAT5A interactions

HELZ NCOR2 EP300

3.78e-04131223int:STAT5A
InteractionMED15 interactions

MED12L MED15 NCOA6

3.78e-04131223int:MED15
InteractionRUNX1 interactions

NCOR2 CCNK EP300 NOTCH1

3.82e-04324224int:RUNX1
InteractionCXXC1 interactions

NCOA6 EP300 KMT2D

3.86e-04132223int:CXXC1
InteractionMAFA interactions

NCOA6 KMT2D

3.93e-0427222int:MAFA
InteractionCREBBP interactions

HELZ NCOR2 NCOA6 EP300 KMT2D

3.95e-04599225int:CREBBP
InteractionCARMIL2 interactions

MBD5 NOTCH1

4.23e-0428222int:CARMIL2
InteractionNR2F2 interactions

FOXP2 NCOR2 EP300

4.49e-04139223int:NR2F2
InteractionSRF interactions

NCOR2 NCOA6 ARID2

4.49e-04139223int:SRF
InteractionTLX2 interactions

MIDEAS NCOR2 KMT2D

4.78e-04142223int:TLX2
InteractionNFIB interactions

MIDEAS NCOR2 KMT2D

4.78e-04142223int:NFIB
InteractionNUP43 interactions

MIDEAS NCOR2 NCOA6 ARID2 KMT2D

4.80e-04625225int:NUP43
InteractionELP3 interactions

MED15 EP300 KMT2D

5.50e-04149223int:ELP3
InteractionRTF1 interactions

MED15 CCNK EP300

5.61e-04150223int:RTF1
InteractionPAXIP1 interactions

CCNK NCOA6 EP300 KMT2D

5.62e-04359224int:PAXIP1
InteractionETV5 interactions

EP300 KMT2D

5.88e-0433222int:ETV5
GeneFamilyAtaxins|Trinucleotide repeat containing

MED15 FOXP2 NCOR2 MAML3 KMT2D

3.79e-1125195775
GeneFamilyCyclins|Mediator complex

MED12L MED15

5.42e-04331921061
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MIDEAS NCOR2

1.40e-0353192532
CoexpressionGSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN

MED15 MIDEAS NCOR2 KMT2D SUPT20H

7.40e-07200235M9463
CoexpressionGSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP

MED15 EP300 SUSD4 QRICH1

2.60e-05200234M9889
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 FOXP2 HS6ST2 SUSD4

1.29e-0616023403b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 FOXP2 HS6ST2 SUSD4

1.85e-06175234e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 FOXP2 HS6ST2 SUSD4

1.98e-061782344df6218b20c2f076c22346d23260964cc0d73e65
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 FOXP2 HS6ST2 SUSD4

2.07e-061802349e09b3dfe344b5d50520711513d389865d73a861
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 MBD5 FOXP2 NFAT5

2.51e-06189234830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

MBD5 NFAT5 HELZ ARID2

2.67e-06192234916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

MBD5 NFAT5 HELZ ARID2

2.73e-06193234e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

CPEB3 MBD5 FOXP2 MAML3

3.08e-0619923494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MED12L FOXP2 SUSD4

3.82e-05128233076ba9de63b9a4b5a2f7e7924b9a86e8eafce91f
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

NFAT5 HS6ST2 KMT2D

4.48e-05135233ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell367C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FOXP2 MAML3 JHY

7.01e-05157233f511871e1a004c6e9af08ee325ab1bfc41807487
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 FOXP2 HS6ST2

9.19e-051722331565f38266891c3acf49778838de134c5dee5460
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

NFAT5 NCOR2 ARID2

9.84e-051762333de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

NFAT5 NCOR2 ARID2

1.00e-0417723382fdd6185b368f54f03de389427cbe3071d21a99
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 FOXP2 HS6ST2

1.02e-04178233dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCellCOVID-19_Mild-NK_CD56bright|COVID-19_Mild / Disease condition and Cell class

MAML3 HS6ST2 NOTCH1

1.03e-0417923390e7a4af195aa2332b07a9f06cde63e72ff49255
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CPEB3 KMT2D JHY

1.09e-041822331923932a9c60e9ec33db69ded441210d1fb07bec
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 FOXP2 HS6ST2

1.09e-04182233041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CPEB3 KMT2D JHY

1.09e-0418223369ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.10e-0418323331ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.12e-04184233e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.14e-04185233898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 FOXP2 HS6ST2

1.14e-0418523303f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.16e-041862331850583d23903d08226aeb0edb3e07b0994330e4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.16e-041862334dafc215c42e7949f932a3627359c107943b5d6b
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

NFAT5 EP300 ARID2

1.16e-0418623303db813598b67b1e08f759758a1c2023396921fa
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.18e-04187233b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.18e-041872337ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.20e-041882332ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.20e-041882333cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCellwk_15-18-Hematologic-Myeloid-Basophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CPEB3 MAML3 NOTCH1

1.20e-041882333638d85452de15a060146628fbbad9d2a36feb13
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.21e-04189233f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MED12L HS6ST2 SUSD4

1.21e-04189233977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.23e-041902333dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.23e-04190233b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.23e-04190233cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MED12L HS6ST2 SUSD4

1.23e-04190233e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.25e-04191233963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.25e-04191233f631749ef1f2270133664cf5eb4cf545a8482bd3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB3 HS6ST2 SUSD4

1.27e-04192233562df5e87038c500dd3a003fe5374cb31946b145
ToppCellControl-NK_CD56bright|Control / Disease condition and Cell class

ZNF853 MAML3 NOTCH1

1.29e-041932338b1e7a226a6057e1097c1525984127b54e823876
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

MBD5 FOXP2 MAML3

1.35e-04196233ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

MBD5 FOXP2 MAML3

1.39e-041982331996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MED12L FOXP2 MAML3

1.44e-04200233dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MED12L FOXP2 MAML3

1.44e-04200233a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MED12L FOXP2 MAML3

1.44e-0420023321bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MED12L FOXP2 MAML3

1.44e-042002333bba5219453322198e8fdb0921d5f8c403598751
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MED12L FOXP2 MAML3

1.44e-0420023333036d21c1c82109284473a515c4f890b33fdd5c
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MED12L FOXP2 MAML3

1.44e-04200233a20dce14f94777687aad57d6fbe3258ad376f63f
Drug2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A_EA

MED15 NFAT5 CCNK NOTCH1 SUPT20H

9.98e-071942251060_UP
Drughalofenate

NCOR2 EP300

5.34e-064222CID000033584
DiseaseAdenoid Cystic Carcinoma

FOXP2 MAML3 EP300 NOTCH1

1.05e-06100234C0010606
DiseaseSquamous cell carcinoma of esophagus

EP300 NOTCH1 KMT2D

5.46e-0595233C0279626
Diseaseautism spectrum disorder (is_implicated_in)

MBD5 FOXP2

6.93e-0516232DOID:0060041 (is_implicated_in)
DiseaseT-Cell Lymphoma

EP300 KMT2D

6.93e-0516232C0079772
Diseaseneuroticism measurement, wellbeing measurement, depressive symptom measurement

FOXP2 MAML3

9.86e-0519232EFO_0007006, EFO_0007660, EFO_0007869
Diseaseage at first birth measurement

FOXP2 MAML3 HS6ST2

1.09e-04120233EFO_0009101
Diseasepuberty onset measurement

NFAT5 NCOA6 JHY

1.24e-04125233EFO_0005677
DiseaseBladder Neoplasm

EP300 NOTCH1 KMT2D

1.73e-04140233C0005695
DiseaseMalignant neoplasm of urinary bladder

EP300 NOTCH1 KMT2D

1.76e-04141233C0005684
DiseaseCraniofacial Abnormalities

FOXP2 EP300 NOTCH1

2.38e-04156233C0376634
Diseasealcohol use disorder (implicated_via_orthology)

EP300 ARID2 NOTCH1

4.57e-04195233DOID:1574 (implicated_via_orthology)
DiseaseBreast adenocarcinoma

EP300 NOTCH1

4.68e-0441232C0858252
DiseaseNeoplasm of uncertain or unknown behavior of breast

EP300 NOTCH1

4.68e-0441232C0496956
Diseasechronotype measurement

CPEB3 FOXP2 ARID2 KMT2D JHY

5.07e-04882235EFO_0008328
Diseaseneuroticism measurement

MBD5 FOXP2 NCOR2 HS6ST2 QRICH1

5.82e-04909235EFO_0007660
DiseaseDiffuse Large B-Cell Lymphoma

EP300 KMT2D

8.42e-0455232C0079744
Diseaseoral squamous cell carcinoma (is_marker_for)

ARID2 KMT2D

1.10e-0363232DOID:0050866 (is_marker_for)
Diseasediet measurement

MBD5 FOXP2 MAML3 NCOA6 ARID2

1.11e-031049235EFO_0008111
Diseaseage at initiation of smoking

FOXP2 MAML3

1.21e-0366232EFO_0021784
Diseasebreast carcinoma (is_marker_for)

EP300 KMT2D

1.21e-0366232DOID:3459 (is_marker_for)
Diseaseaggressive behaviour measurement, ADHD symptom measurement

FOXP2 NCOA6

1.28e-0368232EFO_0007826, EFO_0007860
Diseaseschizophrenia (is_implicated_in)

MED15 FOXP2

1.68e-0378232DOID:5419 (is_implicated_in)
Diseaseirritability measurement

FOXP2 NCOA6

1.86e-0382232EFO_0009594
Diseasefeeling nervous measurement

MBD5 NCOA6

2.09e-0387232EFO_0009597

Protein segments in the cluster

PeptideGeneStartEntry
PTQPQVQAKNQQNQQ

EP300

481

Q09472
QKQLQQQQQQPPSQL

AKAP2

281

Q9Y2D5
QQPQQVQMQVQPQQS

ARID2

1031

Q68CP9
QPQQKDPQQPAQQQQ

CCNK

301

O75909
PQTQQEQQIQVQQPQ

QRICH1

86

Q2TAL8
QQQQQQQQQQPMPRS

NCOR2

501

Q9Y618
QPQNLQMQQQNLQPA

NOTCH1

2386

P46531
RLLQMQQPQQPQPQQ

MED12L

2061

Q86YW9
QNNPPRQQQNQNKPL

JHY

391

Q6NUN7
NPLMPYIQQQQQQQQ

MAML3

626

Q96JK9
PQQMQQILQQQVLSP

FOXP2

101

O15409
QQQQQQQALQAQPPI

MED15

256

Q96RN5
NQQQNNLPEQPNQIP

HELZ

1381

P42694
PQPNQVVQQQSQLNQ

HELZ

1396

P42694
VVQQQSQLNQQPQQP

HELZ

1401

P42694
FNPNQNPMANQEQQN

NFAT5

1291

O94916
QMNPANFPQLQQQQQ

NCOA6

251

Q14686
KTQPQPQQQQRQQQQ

CPEB3

11

Q8NE35
QQQQQQQAALPQMPL

MIDEAS

256

Q6PJG2
NNNQMFPPNQQQQQL

MBD5

971

Q9P267
PNANQNLTQNLMQNL

HS6ST2

551

Q96MM7
QPQSQQQQPQHIQLQ

SUPT20HL1

746

Q3ZLR7
QQQQQQLSQFTPQQP

SUPT20H

636

Q8NEM7
QQQQQQQPQSPQRLL

SUSD4

16

Q5VX71
QQQQEQLQQQQLQPP

ZNF853

296

P0CG23
AQPMGSLQQLQQQQQ

KMT2D

3891

O14686
PQQQQQLQALLMQRQ

KMT2D

4216

O14686