Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

DNAH3 ATP7B IPO8 MYO5A MYO7B LONP2 ABCA12 ABCA13 MYO19 PEX1 KIF12 SRPRA FANCM DDX6 ORC1 DQX1 RECQL4 KIF19 HFM1 MYO15A

3.59e-0761417220GO:0140657
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR1 ITPR2 ITPR3

6.28e-0731723GO:0005220
GeneOntologyMolecularFunctionATP hydrolysis activity

DNAH3 ATP7B LONP2 ABCA12 ABCA13 MYO19 PEX1 KIF12 SRPRA FANCM DDX6 ORC1 DQX1 RECQL4 KIF19 HFM1

1.43e-0644117216GO:0016887
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH3 MYO5A MYO7B MYO19 KIF12 KIF19 MYO15A

7.36e-051181727GO:0003774
GeneOntologyMolecularFunctionkinase binding

PRKD2 ERBB2 ANK2 MYO5A POLA1 RAB11FIP2 CCND1 PFKFB1 PTAFR OPA1 PTK2 MAPK8IP3 IQGAP1 SIRPG MLKL CSPG4 PKD1 SYN1 PLCB4 MAPK4 MAPK6

9.41e-0596917221GO:0019900
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DNAH3 ATP7B LONP2 ABCA12 ABCA13 MYO19 PEX1 KIF12 SRPRA RAB20 FANCM OPA1 DDX6 ORC1 DQX1 RECQL4 KIF19 HFM1

1.31e-0477517218GO:0017111
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

ITPR1 ITPR2 ITPR3 KCNA10

1.79e-04331724GO:0005217
GeneOntologyMolecularFunctionprotein kinase binding

PRKD2 ERBB2 ANK2 MYO5A POLA1 RAB11FIP2 CCND1 PTAFR PTK2 MAPK8IP3 IQGAP1 SIRPG MLKL CSPG4 PKD1 SYN1 PLCB4 MAPK4 MAPK6

1.96e-0487317219GO:0019901
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

ITPR1 ITPR2 ITPR3

2.13e-04141723GO:0070679
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

ITPR1 ITPR2 ITPR3 KCNA10 KCNH2 CATSPER4 KCNT1

2.14e-041401727GO:0099094
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO5A MYO7B MYO19 MYO15A

3.12e-04381724GO:0000146
GeneOntologyMolecularFunctionpyrophosphatase activity

DNAH3 ATP7B LONP2 ABCA12 ABCA13 MYO19 PEX1 KIF12 SRPRA RAB20 FANCM OPA1 DDX6 ORC1 DQX1 RECQL4 KIF19 HFM1

3.45e-0483917218GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DNAH3 ATP7B LONP2 ABCA12 ABCA13 MYO19 PEX1 KIF12 SRPRA RAB20 FANCM OPA1 DDX6 ORC1 DQX1 RECQL4 KIF19 HFM1

3.50e-0484017218GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DNAH3 ATP7B LONP2 ABCA12 ABCA13 MYO19 PEX1 KIF12 SRPRA RAB20 FANCM OPA1 DDX6 ORC1 DQX1 RECQL4 KIF19 HFM1

3.50e-0484017218GO:0016818
GeneOntologyMolecularFunctiontestosterone 16-alpha-hydroxylase activity

CYP3A4 CYP3A43

4.38e-0441722GO:0008390
GeneOntologyMolecularFunction6-phosphofructo-2-kinase activity

PFKFB1 PFKFB3

4.38e-0441722GO:0003873
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

ITPR1 ITPR2 ITPR3

4.66e-04181723GO:0015278
GeneOntologyMolecularFunctionsmall GTPase binding

IPO8 RGPD8 MYO5A MYCBP2 RAB11FIP2 RAB11FIP1 IQGAP1 GGA3 APPL2 HACE1

4.84e-0432117210GO:0031267
GeneOntologyMolecularFunctiontestosterone 6-beta-hydroxylase activity

CYP3A4 CYP3A43

7.25e-0451722GO:0050649
GeneOntologyMolecularFunctionfructose-2,6-bisphosphate 2-phosphatase activity

PFKFB1 PFKFB3

7.25e-0451722GO:0004331
GeneOntologyMolecularFunctionvitamin D 23-hydroxylase activity

CYP3A4 CYP3A43

7.25e-0451722GO:0062179
GeneOntologyMolecularFunction1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity

CYP3A4 CYP3A43

7.25e-0451722GO:0062181
GeneOntologyMolecularFunctionshort-chain fatty acid transmembrane transporter activity

SLC22A25 SLC22A9

7.25e-0451722GO:0015636
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

ATP7B GRM7 SLC40A1 ITPR1 ITPR2 ITPR3 SLC9A3 KCNA10 KCNH2 CATSPER4 PKD1 KCNT1

7.26e-0446517212GO:0046873
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP3A4 CYP3A43 CYP2G1P CYP2U1

8.33e-04491724GO:0016712
GeneOntologyMolecularFunctioncalcium channel activity

GRM7 ITPR1 ITPR2 ITPR3 CATSPER4 PKD1

8.89e-041291726GO:0005262
GeneOntologyMolecularFunctionvitamin D3 25-hydroxylase activity

CYP3A4 CYP3A43

1.08e-0361722GO:0030343
GeneOntologyMolecularFunctionvitamin D 24-hydroxylase activity

CYP3A4 CYP3A43

1.08e-0361722GO:0070576
GeneOntologyMolecularFunctionfour-way junction helicase activity

FANCM RECQL4

1.08e-0361722GO:0009378
GeneOntologyMolecularFunctionGTPase binding

IPO8 RGPD8 MYO5A MYCBP2 RAB11FIP2 RAB11FIP1 IQGAP1 GGA3 APPL2 HACE1

1.16e-0336017210GO:0051020
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

ITPR1 ITPR2 ITPR3 KCNA10 KCNH2 CATSPER4 KCNT1

1.45e-031931727GO:0015276
GeneOntologyMolecularFunctionphosphofructokinase activity

PFKFB1 PFKFB3

1.51e-0371722GO:0008443
GeneOntologyMolecularFunctionvitamin D 25-hydroxylase activity

CYP3A4 CYP3A43

1.51e-0371722GO:0070643
GeneOntologyMolecularFunctionligand-gated channel activity

ITPR1 ITPR2 ITPR3 KCNA10 KCNH2 CATSPER4 KCNT1

1.62e-031971727GO:0022834
GeneOntologyMolecularFunctiontransporter activity

SLC22A25 ATP7B IPO8 ABCA12 ABCA13 PEX1 XKR8 SLC22A24 GRM7 SLC40A1 GGA3 ITPR1 ITPR2 ITPR3 SLC22A9 SLC9A3 KCNA10 KCNH2 CATSPER4 PKD1 GJA10 KCNT1

1.66e-03128917222GO:0005215
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

GRM7 ITPR1 ITPR2 ITPR3 CATSPER4 PKD1

1.99e-031511726GO:0015085
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor

CYP3A4 CYP3A43

2.00e-0381722GO:0033695
GeneOntologyMolecularFunctioncaffeine oxidase activity

CYP3A4 CYP3A43

2.00e-0381722GO:0034875
GeneOntologyMolecularFunctionestrogen 2-hydroxylase activity

CYP3A4 CYP3A43

2.00e-0381722GO:0101021
GeneOntologyMolecularFunctionmyosin light chain binding

SPATA6L MYO19

2.00e-0381722GO:0032027
GeneOntologyMolecularFunctionligand-gated calcium channel activity

ITPR1 ITPR2 ITPR3

2.36e-03311723GO:0099604
GeneOntologyMolecularFunctionmonoatomic cation channel activity

GRM7 ITPR1 ITPR2 ITPR3 KCNA10 KCNH2 CATSPER4 PKD1 KCNT1

2.98e-033431729GO:0005261
GeneOntologyMolecularFunctionactin binding

KLHL1 MYO5A MYO7B MYO19 PTK2 IQGAP1 ARPC2 SYNE2 SYN1 MYO15A MYBPC3

2.99e-0347917211GO:0003779
GeneOntologyMolecularFunctioncytoskeletal protein binding

SPATA6L KLHL1 ANK2 MYO5A MYO7B MYO19 IFT81 KIF12 OPA1 PTK2 MAPK8IP3 IQGAP1 ARPC2 DLC1 SYNE2 KIF19 SYN1 MYO15A MYBPC3

3.01e-03109917219GO:0008092
GeneOntologyMolecularFunctionsteroid hydroxylase activity

CYP3A4 CYP3A43 CYP2U1

3.09e-03341723GO:0008395
GeneOntologyMolecularFunctionsugar-phosphatase activity

PFKFB1 PFKFB3

3.17e-03101722GO:0050308
GeneOntologyMolecularFunctionmitogen-activated protein kinase binding

PTAFR IQGAP1 PLCB4

3.36e-03351723GO:0051019
GeneOntologyMolecularFunctionaromatase activity

CYP3A4 CYP3A43 CYP2G1P

3.36e-03351723GO:0070330
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

PRKD2 ERBB2 RIOK1 HTATIP2 CCND1 PFKFB1 PFKFB3 PTK2 MLKL TIE1 PIP5K1B MAPK4 MAPK6 MAP2K5

3.38e-0370917214GO:0016773
GeneOntologyMolecularFunctioncarbohydrate phosphatase activity

PFKFB1 PFKFB3

3.86e-03111722GO:0019203
GeneOntologyMolecularFunctionestrogen 16-alpha-hydroxylase activity

CYP3A4 CYP3A43

3.86e-03111722GO:0101020
GeneOntologyMolecularFunctiontoxin transmembrane transporter activity

SLC22A25 SLC22A9

4.60e-03121722GO:0019534
GeneOntologyMolecularFunctionlipid binding

SESTD1 CYP3A4 CYP3A43 FFAR3 GPR42 ARHGAP26 PEX1 PTAFR OPA1 IQGAP1 GGA3 ITPR1 ITPR2 ITPR3 SLC9A3 DLC1 APPL2

5.20e-0398817217GO:0008289
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

ZSWIM8 ANK2 TBL1Y PRAMEF22 PRAMEF19 ARHGAP26 HTATIP2 PEX1 CCND1 TBL1XR1 MAPK8IP3 IQGAP1 ANKRD13A BEND6 SYNE2 SYN1 BRD1 MED26 MED13

5.37e-03116017219GO:0030674
GeneOntologyMolecularFunctionMAP-kinase scaffold activity

MAPK8IP3 IQGAP1

5.41e-03131722GO:0005078
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR1 ITPR2 ITPR3

4.36e-0591713GO:0031095
GeneOntologyCellularComponentplatelet dense tubular network

ITPR1 ITPR2 ITPR3

8.46e-05111713GO:0031094
GeneOntologyCellularComponentmotile cilium

ADCY10 DNAH3 PRAMEF22 PRAMEF19 IFT81 DDX6 DNAAF5 CATSPER4 PKD1 CFAP45 VPS13A

1.71e-0435517111GO:0031514
GeneOntologyCellularComponent9+2 non-motile cilium

CDH23 STRC STRCP1

1.83e-04141713GO:0097732
GeneOntologyCellularComponentkinocilium

CDH23 STRC STRCP1

1.83e-04141713GO:0060091
GeneOntologyCellularComponentconcave side of sperm head

DDX6 ARPC2

1.99e-0431712GO:0061830
GeneOntologyCellularComponentcilium

ADCY10 DNAH3 MYO5A PRAMEF22 PRAMEF19 IFT81 CDH23 PTK2 DDX6 DNAAF5 CATSPER4 KIF19 PKD1 CFAP45 VPS13A ANKMY2 STRC STRCP1

4.19e-0489817118GO:0005929
GeneOntologyCellularComponentsmooth endoplasmic reticulum

MYO5A MAPK8IP3 ITPR1 PLCB4

5.40e-04461714GO:0005790
GeneOntologyCellularComponentstereocilium tip

CDH23 STRC STRCP1

7.39e-04221713GO:0032426
GeneOntologyCellularComponentcytoplasmic vesicle membrane

ERBB2 ABCA12 ABCA13 ARHGAP26 UBR4 RAB11FIP2 CC2D1A PTAFR RAB11FIP1 RAB20 IQGAP1 GGA3 ITPR1 ITPR2 ARPC2 ITPR3 SLC9A3 APPL2 PKD1 VPS13A SYN1 SEC23B

1.02e-03130717122GO:0030659
GeneOntologyCellularComponentbasal part of cell

ADCY10 ERBB2 SLC22A25 ATP7B ANK2 SLC40A1 PTK2 IQGAP1 SLC22A9 PKD1

1.14e-0337817110GO:0045178
GeneOntologyCellularComponentvesicle membrane

ERBB2 ABCA12 ABCA13 ARHGAP26 UBR4 RAB11FIP2 CC2D1A PTAFR RAB11FIP1 RAB20 IQGAP1 GGA3 ITPR1 ITPR2 ARPC2 ITPR3 SLC9A3 APPL2 PKD1 VPS13A SYN1 SEC23B

1.22e-03132517122GO:0012506
GeneOntologyCellularComponentbasolateral plasma membrane

ERBB2 SLC22A25 ATP7B ANK2 SLC40A1 PTK2 IQGAP1 SLC22A9 PKD1

1.32e-033201719GO:0016323
GeneOntologyCellularComponentmyosin complex

MYO5A MYO7B MYO19 MYO15A

1.39e-03591714GO:0016459
GeneOntologyCellularComponentruffle

ERBB2 MYO5A IQGAP1 ARPC2 DLC1 APPL2 CSPG4

1.57e-032061717GO:0001726
GeneOntologyCellularComponent90S preribosome

NOL6 UTP20 MPHOSPH10

1.68e-03291713GO:0030686
GeneOntologyCellularComponentperinuclear region of cytoplasm

ADCY10 ERBB2 ATP7B ANK2 RGPD8 CISD2 TRAIP XKR8 PTK2 DDX6 MAPK8IP3 ITPR1 ITPR3 ANKRD13A KCNH2 PPM1F SEC23B

1.74e-0393417117GO:0048471
GeneOntologyCellularComponentleading edge membrane

ERBB2 MAPK8IP3 ARPC2 DLC1 APPL2 CSPG4 SYNE2

1.75e-032101717GO:0031256
MousePhenoabnormal somatic nervous system physiology

TAS1R3 FFAR3 GPR42 CDH23 STRC MYO15A KCNT1 STRCP1

1.25e-06831348MP:0005423
MousePhenoabnormal sensory neuron physiology

FFAR3 GPR42 CDH23 STRC MYO15A KCNT1 STRCP1

5.57e-06721347MP:0010055
DomainP-loop_NTPase

ADCY10 DNAH3 MYO5A MYO7B LONP2 ABCA12 ABCA13 MYO19 PEX1 KIF12 SRPRA PFKFB1 PFKFB3 RAB20 FANCM OPA1 DDX6 IQGAP1 ORC1 DQX1 RECQL4 KIF19 HFM1 MYO15A

5.59e-0784816724IPR027417
DomainInsP3_rcpt-bd

ITPR1 ITPR2 ITPR3

7.02e-0731673IPR000493
Domain-

ADCY10 DNAH3 MYO7B LONP2 ABCA12 ABCA13 MYO19 PEX1 SRPRA PFKFB1 PFKFB3 RAB20 FANCM OPA1 DDX6 ORC1 DQX1 RECQL4 HFM1 MYO15A

1.19e-05746167203.40.50.300
DomainRIH_assoc-dom

ITPR1 ITPR2 ITPR3

1.38e-0561673IPR013662
DomainIns145_P3_rec

ITPR1 ITPR2 ITPR3

1.38e-0561673PF08709
DomainRIH_assoc

ITPR1 ITPR2 ITPR3

1.38e-0561673PF08454
DomainRIH_dom

ITPR1 ITPR2 ITPR3

1.38e-0561673IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR2 ITPR3

1.38e-0561673IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR2 ITPR3

1.38e-0561673IPR015925
Domain-

ITPR1 ITPR2 ITPR3

1.38e-05616731.25.10.30
DomainRYDR_ITPR

ITPR1 ITPR2 ITPR3

1.38e-0561673PF01365
DomainCXorf40

EOLA1 EOLA2

7.95e-0521672IPR033615
DomainMIR

ITPR1 ITPR2 ITPR3

8.05e-05101673PF02815
DomainMIR_motif

ITPR1 ITPR2 ITPR3

8.05e-05101673IPR016093
DomainMIR

ITPR1 ITPR2 ITPR3

8.05e-05101673PS50919
DomainMIR

ITPR1 ITPR2 ITPR3

8.05e-05101673SM00472
DomainASCH_domain

EOLA1 EOLA2

2.37e-0431672IPR007374
DomainASCH

EOLA1 EOLA2

2.37e-0431672SM01022
DomainMAPK_ERK3/4

MAPK4 MAPK6

2.37e-0431672IPR008350
DomainARM-type_fold

IPO8 UBR4 USP24 HSF2BP PSMD5 ITPR1 ITPR2 DNAAF5 SF3B1 MROH7 UTP20

2.44e-0433916711IPR016024
DomainAAA

DNAH3 LONP2 ABCA12 ABCA13 PEX1 SRPRA ORC1

3.17e-041441677SM00382
DomainAAA+_ATPase

DNAH3 LONP2 ABCA12 ABCA13 PEX1 SRPRA ORC1

3.17e-041441677IPR003593
DomainMyosin_head_motor_dom

MYO5A MYO7B MYO19 MYO15A

3.59e-04381674IPR001609
DomainMYOSIN_MOTOR

MYO5A MYO7B MYO19 MYO15A

3.59e-04381674PS51456
DomainMyosin_head

MYO5A MYO7B MYO19 MYO15A

3.59e-04381674PF00063
DomainMYSc

MYO5A MYO7B MYO19 MYO15A

3.59e-04381674SM00242
Domain6Phosfructo_kin

PFKFB1 PFKFB3

4.71e-0441672IPR013079
DomainGPR40-rel_orph

FFAR3 GPR42

4.71e-0441672IPR013312
Domain6Pfruct_kin

PFKFB1 PFKFB3

4.71e-0441672IPR003094
Domain6PF2K

PFKFB1 PFKFB3

4.71e-0441672PF01591
DomainIon_trans_dom

ITPR1 ITPR2 ITPR3 KCNA10 KCNH2 CATSPER4

5.62e-041141676IPR005821
DomainIon_trans

ITPR1 ITPR2 ITPR3 KCNA10 KCNH2 CATSPER4

5.62e-041141676PF00520
DomainPUA-like_domain

LONP2 EOLA1 EOLA2

6.12e-04191673IPR015947
Domain-

ACP2 PFKFB1 PFKFB3

7.16e-042016733.40.50.1240
DomainHis_PPase_superfam

ACP2 PFKFB1 PFKFB3

7.16e-04201673IPR029033
DomainCyt_P450_E_grp-II

CYP3A4 CYP3A43

7.81e-0451672IPR002402
DomainIQ

MYO5A MYO7B MYO19 IQGAP1 MYO15A

7.97e-04811675SM00015
DomainRBD-FIP

RAB11FIP2 RAB11FIP1

1.16e-0361672PF09457
DomainCyt_P450_E_CYP3A

CYP3A4 CYP3A43

1.16e-0361672IPR008072
DomainRab-bd_FIP-RBD

RAB11FIP2 RAB11FIP1

1.16e-0361672IPR019018
DomainFIP_RBD

RAB11FIP2 RAB11FIP1

1.16e-0361672PS51511
DomainIQ_motif_EF-hand-BS

MYO5A MYO7B MYO19 IQGAP1 MYO15A

1.28e-03901675IPR000048
DomainIQ

MYO5A MYO7B MYO19 IQGAP1 MYO15A

1.48e-03931675PS50096
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3 PLCB4

1.19e-06101254M47661
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3 PLCB4

1.85e-06111254M49033
PathwayKEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3 PLCB4

3.96e-06131254M47656
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

6.72e-0651253M49000
PathwayKEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.34e-0561253M47960
PathwayKEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3 PLCB4

2.56e-05201254M47688
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3 PLCB4

3.14e-05211254M47689
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3 PLCB4

3.81e-05221254M47690
PathwayKEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3 PLCB4

3.81e-05221254M47675
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3 PLCB4

4.58e-05231254M47676
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

5.50e-0591253M47852
PathwayKEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY

PTAFR ITPR1 ITPR2 ITPR3 PLCB4

7.79e-05501255M47951
PathwayREACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION

ITPR1 ITPR2 ITPR3

1.07e-04111253M27466
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

1.82e-04131253M47696
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

1.82e-04131253M47751
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3

1.82e-04131253MM14553
PathwayWP_GPR40_PATHWAY

ITPR3 PKD1 PLCL1

2.86e-04151253M39526
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3

3.50e-04161253M26945
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP3A4 CYP3A43 CYP2U1

5.04e-04181253MM14843
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

IQGAP1 ITPR1 ITPR2 ITPR3

5.08e-04421254M791
PathwayKEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM

ITPR1 ITPR2 ITPR3 PIP5K1B PLCB4

5.65e-04761255M9052
PathwayREACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION

ITPR1 ITPR2 ITPR3

5.94e-04191253M27423
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

5.94e-04191253M47760
PathwayKEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

5.94e-04191253M47733
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ZSWIM8 MYO5A MYCBP2 POLA1 UBR4 NOL6 USP24 LARP4 GFPT1 IQGAP1 ITPR3 SF3B1 SUPT6H SYNE2 OASL UTP20 MPHOSPH10 SEC23B

4.92e-096531721822586326
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SESTD1 ANK2 RGPD8 MYO5A MYCBP2 TBL1Y UBR4 HECTD4 TBL1XR1 OPA1 PTK2 MAPK8IP3 IQGAP1 ARPC2 SIRPG SF3B1 TMEM259 SYNE2 SYN1 PLCL1 KCNT1

1.47e-089631722128671696
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR1 ITPR2 ITPR3

1.19e-073172310874040
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR1 ITPR2 ITPR3

1.19e-073172320395455
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR1 ITPR2 ITPR3

1.19e-073172317437169
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR1 ITPR2 ITPR3

1.19e-073172318547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR1 ITPR2 ITPR3

1.19e-073172336350267
Pubmed

The versatility and universality of calcium signalling.

ITPR1 ITPR2 ITPR3

1.19e-073172311413485
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

1.19e-073172326009177
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR1 ITPR2 ITPR3

1.19e-07317231693919
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR1 ITPR2 ITPR3

1.19e-073172323955339
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR1 ITPR2 ITPR3

1.19e-073172331979185
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR1 ITPR2 ITPR3

1.19e-073172324904548
Pubmed

Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.

ITPR1 ITPR2 ITPR3

1.19e-07317239858485
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR1 ITPR2 ITPR3

1.19e-07317239808793
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR1 ITPR2 ITPR3

1.19e-073172318194433
Pubmed

IP3 receptors regulate vascular smooth muscle contractility and hypertension.

ITPR1 ITPR2 ITPR3

1.19e-073172327777977
Pubmed

Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.

ITPR1 ITPR2 ITPR3

1.19e-073172317581770
Pubmed

Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.

ITPR1 ITPR2 ITPR3

1.19e-073172318241669
Pubmed

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

ITPR1 ITPR2 ITPR3

1.19e-073172319068129
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

1.19e-073172317327232
Pubmed

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.

ITPR1 ITPR2 ITPR3

1.19e-073172316014380
Pubmed

Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.

ITPR1 ITPR2 ITPR3

1.19e-073172317890015
Pubmed

Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.

ITPR1 ITPR2 ITPR3

1.19e-073172323983250
Pubmed

Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.

ITPR1 ITPR2 ITPR3

1.19e-073172320427533
Pubmed

Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.

ITPR1 ITPR2 ITPR3

4.74e-074172325215520
Pubmed

Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

4.74e-074172311163362
Pubmed

Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.

ITPR1 ITPR2 ITPR3

4.74e-074172321424589
Pubmed

Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.

ITPR1 ITPR2 ITPR3

4.74e-074172328615414
Pubmed

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.

ITPR1 ITPR2 ITPR3

4.74e-074172310828023
Pubmed

IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin-NFATc3-Etv2 pathway.

ITPR1 ITPR2 ITPR3

4.74e-074172328419336
Pubmed

IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming.

ITPR1 ITPR2 ITPR3

4.74e-074172335494252
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PRKD2 ERBB2 MYCBP2 ARHGAP26 UBR4 HECTD4 CC2D1A AHDC1 MAPK8IP3 GGA3 ITPR2 ITPR3 ORC1 NHSL1 TMEM259 KCNH2 CSPG4 PKD1 CRAMP1 MED13

6.45e-0711051722035748872
Pubmed

Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle.

ITPR1 ITPR2 ITPR3 PLCB4

7.56e-0715172428578927
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

DNAH3 MXRA5 TAS1R3 POLA1 MYO19 UBR4 SRPRA GFPT1 ITPR2 IGSF10 DQX1 RECQL4 PKD1 VPS13A CSTF2 UTP20

8.83e-077361721629676528
Pubmed

InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences.

ITPR1 ITPR2 ITPR3

1.18e-065172321568942
Pubmed

An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.

CDH23 STRC STRCP1

1.18e-065172324920589
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PRKD2 SESTD1 ZSWIM8 ANK2 MYO5A MYCBP2 IFT81 UBR4 MCF2L2 HECTD4 PSMD5 GFPT1 PTK2 MAPK8IP3 IQGAP1 NPRL2 SF3B1 APPL2 PKD1 ST18 MED13

1.70e-0612851722135914814
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

ITPR1 ITPR2 ITPR3

2.35e-066172323463619
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

ITPR1 ITPR2 ITPR3

2.35e-066172325966694
Pubmed

Sprouty2 regulates PI(4,5)P2/Ca2+ signaling and HIV-1 Gag release.

ITPR1 ITPR2 ITPR3

2.35e-066172321762810
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

ITPR1 ITPR2 ITPR3

2.35e-066172320519450
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

ITPR1 ITPR2 ITPR3

2.35e-066172316844763
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

IPO8 CISD2 MYO19 UBR4 NOL6 SRPRA CCND1 PSMD13 PFKFB3 DDX6 IQGAP1 ITPR1 ITPR2 ARPC2 ITPR3 ANKRD13A DNAAF5 SF3B1 COMMD4 TMEM259 SYNE2 OASL

2.81e-0614401722230833792
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

ERBB2 RIOK1 KLHL1 USP24 CCND1 TBL1XR1 GFPT1 PTK2 KCNA10 KCNH2 PLCL1 MAPK4 MAPK6 MAP2K5 SEC23B

3.90e-067301721534857952
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

ITPR1 ITPR2 ITPR3

4.10e-067172311860456
Pubmed

Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes.

ITPR1 ITPR2 ITPR3

4.10e-067172322495310
Pubmed

Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.

ITPR1 ITPR2 ITPR3 PLCB4

5.68e-0624172410843712
Pubmed

Defining the membrane proteome of NK cells.

ATP7B MYO5A MYCBP2 CISD2 LONP2 ACP2 UBR4 HTATIP2 CC2D1A PSMD13 LARP4 OPA1 DDX6 ITPR1 ITPR2 ITPR3 RECQL4 OASL MED13

5.85e-0611681721919946888
Pubmed

Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.

CDH23 STRC STRCP1

6.54e-068172321165971
Pubmed

Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family.

SLC22A25 SLC22A24 SLC22A9

6.54e-068172317714910
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

ERBB2 UBR4 SRPRA CCND1 PFKFB3 IQGAP1 ITPR1 ITPR2 ITPR3 TIMELESS MPHOSPH10 RNF145

8.60e-065031721236217030
Pubmed

Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.

ITPR1 ITPR2 ITPR3

9.77e-069172325737585
Pubmed

Atm deficiency in the DNA polymerase β null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation.

ITPR1 ITPR2 ITPR3 CSPG4

1.25e-0529172432123907
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

MYCBP2 NOL6 HECTD4 LARP4 GFPT1 DDX6 ITPR1 ITPR2 ITPR3 SUPT6H MPHOSPH10

1.34e-054401721134244565
Pubmed

Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.

CDH23 STRC STRCP1

1.90e-0511172331776257
Pubmed

Type 1 and 3 inositol trisphosphate receptors are required for extra-embryonic vascular development.

ITPR1 ITPR2 ITPR3

1.90e-0511172327514653
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

MXRA5 ARHGAP26 UBR4 NOL6 USP24 GFPT1 ITPR3 TMEM156 PPM1F SYNE2 VPS13A HFM1 MPHOSPH10

1.92e-056381721331182584
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CCDC14 MYO5A MYCBP2 SRPRA PSMD13 HID1 RAB11FIP1 OPA1 ITPR1 ITPR2 ITPR3 NHSL1 PHKB PPM1F SYNE2 VPS13A CSTF2

1.95e-0510491721727880917
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

CISD2 UBR4 USP24 PEX1 SRPRA OPA1 GFPT1 IQGAP1 ITPR3 ANKRD13A DNAAF5 TMEM259 PPM1F CSTF2 UTP20 TIMELESS

1.97e-059421721631073040
Pubmed

Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia.

FFAR3 GPR42

2.43e-052172225637492
Pubmed

Selective tracking of FFAR3-expressing neurons supports receptor coupling to N-type calcium channels in mouse sympathetic neurons.

FFAR3 GPR42

2.43e-052172230478340
Pubmed

Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin.

ITPR2 ITPR3

2.43e-05217229065779
Pubmed

The frameshift polymorphism CYP3A43_74_delA is associated with poor differentiation of breast tumors.

CYP3A4 CYP3A43

2.43e-052172220715157
Pubmed

Intestinal FFA3 mediates obesogenic effects in mice on a Western diet.

FFAR3 GPR42

2.43e-052172235858247
Pubmed

The Pro335 --> Leu polymorphism of type 3 inositol 1,4,5-trisphosphate receptor found in mouse inbred lines results in functional change.

ITPR1 ITPR3

2.43e-052172215890645
Pubmed

ANK2 functionally interacts with KCNH2 aggravating long QT syndrome in a double mutation carrier.

ANK2 KCNH2

2.43e-052172230929919
Pubmed

Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms.

FFAR3 GPR42

2.43e-052172222506074
Pubmed

HER2 reduces breast cancer radiosensitivity by activating focal adhesion kinase in vitro and in vivo.

ERBB2 PTK2

2.43e-052172227286256
Pubmed

The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41.

FFAR3 GPR42

2.43e-052172224748202
Pubmed

Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.

ITPR1 ITPR2

2.43e-052172215201137
Pubmed

Rab11FIP1-deficient mice develop spontaneous inflammation and show increased susceptibility to colon damage.

RAB11FIP2 RAB11FIP1

2.43e-052172235819177
Pubmed

The Cognitive Improvement and Alleviation of Brain Hypermetabolism Caused by FFAR3 Ablation in Tg2576 Mice Is Persistent under Diet-Induced Obesity.

FFAR3 GPR42

2.43e-052172236362376
Pubmed

Cholinergic augmentation of insulin release requires ankyrin-B.

ANK2 ITPR1

2.43e-052172220234002
Pubmed

Inositol 1,4,5-trisphosphate receptor localization and stability in neonatal cardiomyocytes requires interaction with ankyrin-B.

ANK2 ITPR1

2.43e-052172214722080
Pubmed

Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

2.43e-05217228081734
Pubmed

Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.

ITPR1 ITPR2

2.43e-052172223582047
Pubmed

Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids.

FFAR3 GPR42

2.43e-052172220399779
Pubmed

The novel Rab11-FIP/Rip/RCP family of proteins displays extensive homo- and hetero-interacting abilities.

RAB11FIP2 RAB11FIP1

2.43e-052172211944901
Pubmed

The catalytic activity of the mitogen-activated protein kinase extracellular signal-regulated kinase 3 is required to sustain CD4+ CD8+ thymocyte survival.

MAPK4 MAPK6

2.43e-052172225002529
Pubmed

The adrenergic-induced ERK3 pathway drives lipolysis and suppresses energy dissipation.

MAPK4 MAPK6

2.43e-052172232139423
Pubmed

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.

STRC STRCP1

2.43e-052172234910522
Pubmed

Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content.

FFAR3 GPR42

2.43e-052172223110765
Pubmed

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.

FFAR3 GPR42

2.43e-052172226522986
Pubmed

Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.

ITPR2 ITPR3

2.43e-052172215632133
Pubmed

Polymorphisms of HER2 Ile655Val and cyclin D1 (CCND1) G870A are not associated with breast cancer risk but polymorphic allele of HER2 is associated with nodal metastases.

ERBB2 CCND1

2.43e-052172218237245
Pubmed

Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41.

FFAR3 GPR42

2.43e-052172227664183
Pubmed

Heteroligomers of type-I and type-III inositol trisphosphate receptors in WB rat liver epithelial cells.

ITPR1 ITPR3

2.43e-05217227559486
Pubmed

Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating.

ITPR1 ITPR3

2.43e-052172220843799
Pubmed

Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.

ITPR1 ITPR2

2.43e-052172219120126
Pubmed

Paget's disease of the nipple: a copy number of the genes ERBB2 and CCND1 versus expression of the proteins ERBB-2 and cyclin D1.

ERBB2 CCND1

2.43e-052172214689059
Pubmed

Effect of small interfering RNA transfection on FAK and DLC1 mRNA expression in OVCAR-3.

PTK2 DLC1

2.43e-052172222760257
Pubmed

Alterations of the CCND1 and HER-2/neu (ERBB2) proteins in esophageal and gastric cancers.

ERBB2 CCND1

2.43e-052172216490596
Pubmed

G protein coupled receptor 41 regulates fibroblast activation in pulmonary fibrosis via Gαi/o and downstream Smad2/3 and ERK1/2 phosphorylation.

FFAR3 GPR42

2.43e-052172237019194
Pubmed

Rab11-dependent Recycling of the Human Ether-a-go-go-related Gene (hERG) Channel.

RAB11FIP1 KCNH2

2.43e-052172226152716
Pubmed

3-(4-Hydroxy-3-methoxyphenyl) propionic acid contributes to improved hepatic lipid metabolism via GPR41.

FFAR3 GPR42

2.43e-052172238040866
Pubmed

Expression of IP3 receptor isoforms at the nodes of Ranvier in rat sciatic nerve.

ITPR2 ITPR3

2.43e-052172217496801
Pubmed

Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APPswe Alzheimer's Disease Mouse Model.

FFAR3 GPR42

2.43e-052172235408893
Pubmed

FFAR3 modulates insulin secretion and global gene expression in mouse islets.

FFAR3 GPR42

2.43e-052172226091414
Pubmed

Mutational analysis of the ligand binding site of the inositol 1,4,5-trisphosphate receptor.

ITPR1 ITPR3

2.43e-05217228663526
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR2 ITPR3

3.07e-0731233297
GeneFamily6-phosphofructo-2-kinases/fructose-2,6-biphosphatases

PFKFB1 PFKFB3

2.73e-04412321077
GeneFamilyOlfactory receptors, family 3

OR3A2 OR3A3

6.76e-0461232150
GeneFamilyCytochrome P450 family 3

CYP3A4 CYP3A43

1.25e-03812321002
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

GRM7 PTK2 ITPR1 ITPR3 PLCL1 MPHOSPH10

1.50e-031811236694
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RAB11FIP2 CC2D1A RAB11FIP1

1.86e-03361233823
GeneFamilyX-linked mental retardation|RNA helicases

FANCM HFM1

2.43e-031112321168
GeneFamilyMitogen-activated protein kinases

MAPK4 MAPK6

3.41e-03131232651
GeneFamilyATP binding cassette subfamily A

ABCA12 ABCA13

3.96e-03141232805
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

MYO7B PTK2 MYO15A

4.77e-035012331293
CoexpressionGSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_DN

CCDC14 IPO8 HECTD4 IQGAP1 ITPR1 DNAAF5 PHKB PPM1F ZBTB40 TIMELESS

7.63e-0719717210M8271
CoexpressionGSE24210_RESTING_TREG_VS_TCONV_UP

CCPG1 ARHGAP26 SYS1 SLC40A1 ITPR1 ITPR3 MTERF2 SYNE2 VPS13A

7.37e-062001729M7839
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_1000

REC8 IFT81 HSF2BP PFKFB1 HACE1 VPS13A CSTF2 HFM1 DOP1A

1.33e-051871619gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k3_1000
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-7|TCGA-Cervix / Sample_Type by Project: Shred V9

SPATA6L MYO7B ARHGAP26 KIF12 MUC5B HID1 GFPT1 PIP5K1B

2.10e-07159173875a82bbabd97b168dbf1c3f43a9bdad48ce18c78
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 SPATA6L CCDC30 ABCA13 IFT81 GRM7 KIF19 LRRC74B

9.52e-0719417384a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellBAL-Severe-cDC_12|Severe / Compartment, Disease Groups and Clusters

TRAIP NAALADL2 ORC1 TMEM106C RECQL4 TIMELESS PLCB4

4.15e-0616717376c5aa9077ae7eb8887269d405972bd5b31596b19
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SESTD1 SPATA6L PTAFR GRM7 NAALADL2 IQGAP1 ITPR3

7.30e-061821737a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP24 PFKFB1 NAALADL2 ITPR1 PIP5K1B PLCB4 MAPK4

7.30e-0618217375f513bbb7125956eb528e3120de3fd776770a7c3
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA13 POLA1 TRAIP MUC5B ORC1 RECQL4 MAPK4

7.57e-0618317376c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ARHGAP26 HECTD4 PTK2 ITPR2 DLC1 PIP5K1B ST18

8.13e-0618517371d874608aa2062024323512f68889219471b2f00
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 SPATA6L CCDC30 ABCA13 GRM7 IGSF10 KIF19

1.07e-051931737ea345d34440b25f65358a53dc72831998d1c3620
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 UBR4 KIF12 HID1 SLC40A1 GFPT1 SEC23B

1.07e-051931737471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 UBR4 KIF12 HID1 SLC40A1 GFPT1 SEC23B

1.07e-051931737fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MYO7B POLA1 TRAIP CDH23 OASL TIMELESS DOP1A

1.31e-051991737c6d59ed26eadd3c41acfe1b4d929270e00ea3e95
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR26 ABCA12 PFKFB1 MYO15A ST18 KCNT1

1.97e-051421736759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYO7B CYP3A43 CDH23 MTERF2 OASL MPHOSPH10

3.34e-051561736f5889a6899904dfb7f596600b3a76857cf9d5378
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 CCDC30 ABCA13 KIF19 CFAP45 LRRC74B

4.42e-0516417360e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellremission-HSPC|World / disease stage, cell group and cell class

ATP7B SLC40A1 IGSF10 DLC1 KCNH2 PIP5K1B

4.73e-051661736d269ee6f7adb55b05dcb5eaea96629ccb0b2d6e3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 CCDC30 ABCA13 GRM7 KIF19 LRRC74B

5.22e-05169173614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

MYO7B KIF12 MUC5B HID1 GFPT1 PIP5K1B

5.40e-051701736d682178d11d67eb5a02d0c6b3967645e37bcc62a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A25 ABCA12 SLC22A24 ITPR2 SLC22A9 DLC1

5.40e-05170173684d49a1f2989d98bd0acf9ec2d59f1042fc0f55b
ToppCellCOVID-19_Convalescent-Hematopoietic_SC|COVID-19_Convalescent / Disease group, lineage and cell class

ATP7B SLC40A1 IGSF10 DLC1 KCNH2 PIP5K1B

5.40e-0517017368a73d5334eed1cd9fdcc3ebeae0bdf9f945c228a
ToppCellPBMC-Convalescent-Hematopoietic-HSPC-HSPC|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP7B SLC40A1 IGSF10 DLC1 KCNH2 PIP5K1B

5.58e-0517117362031797d579ce373921affad70da6e50eec13664
ToppCellremission-HSPC|remission / disease stage, cell group and cell class

ATP7B SLC40A1 IGSF10 DLC1 KCNH2 PIP5K1B

5.58e-05171173641b424e58470a2fc25632aea50a37c7c5ea17645
ToppCellPBMC-Convalescent-Hematopoietic-HSPC-HSPC-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP7B SLC40A1 IGSF10 DLC1 KCNH2 PIP5K1B

5.58e-051711736a4e13b304ef414722ffdc06560deeab41785e956
ToppCellPBMC-Convalescent-Hematopoietic-HSPC|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP7B SLC40A1 IGSF10 DLC1 KCNH2 PIP5K1B

5.58e-051711736172db31a37b72fb87fe5f0f79da51866b90dd1ad
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

ATP7B SLC40A1 IGSF10 GAL DLC1 KCNH2

5.58e-0517117363ecd0a074344179c57eb2d9a857ba594904d00fa
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

MYO7B KIF12 MUC5B HID1 GFPT1 PIP5K1B

5.58e-0517117361af575809b3334bfaa019ff26c56e6cb03c82ee8
ToppCellPBMC-Convalescent-Hematopoietic-HSPC-HSPC-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ATP7B SLC40A1 IGSF10 DLC1 KCNH2 PIP5K1B

5.76e-0517217368fd3db757d54949bd583d5f0eadf63a32342cb9d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A25 ABCA12 SLC22A24 ITPR2 SLC22A9 DLC1

5.76e-051721736cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCellPBMC-Convalescent-Hematopoietic-HSPC|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

ATP7B SLC40A1 IGSF10 DLC1 KCNH2 PIP5K1B

5.76e-051721736da78f7a71b7f05c5c484c9ed19ba37c55d35e870
ToppCellPBMC-Convalescent-Hematopoietic-HSPC-HSPC|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

ATP7B SLC40A1 IGSF10 DLC1 KCNH2 PIP5K1B

5.76e-051721736382cb5fea099110eb026a8bba6cf4c28763ea52f
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM8 USP24 PTAFR RAB11FIP1 AHDC1 GFPT1

6.34e-051751736c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|normal_Lymph_Node / Location, Cell class and cell subclass

CCDC14 CCND1 PFKFB3 RAB11FIP1 HACE1 MED26

6.54e-051761736476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKD2 PFKFB3 TIE1 SYNE2 TIMELESS PLCB4

6.75e-051771736ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKD2 PFKFB3 TIE1 SYNE2 TIMELESS PLCB4

6.75e-051771736f471f7747d6e8db7546899019af9508f48a14f89
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKD2 PFKFB3 TIE1 SYNE2 TIMELESS PLCB4

6.75e-051771736cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCellNS-moderate-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ANK2 CYP3A4 CLDN25 ITPR2 KCNH2 PLCL1

6.75e-05177173699500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCellChildren_(3_yrs)|World / Lineage, Cell type, age group and donor

MYO5A MCF2L2 RAB11FIP1 IQGAP1 OASL PIP5K1B

6.96e-051781736df2ecd3214590b914f2762db57efe780ba038db3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANK2 NAALADL2 ITPR1 ITPR2 SLC9A3 PLCL1

8.11e-05183173631ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

MYO7B ABCA13 SLC22A24 SYNE2 VPS13A PLCL1

8.36e-05184173651ed1ebfdef45149541917c66cbacad87072e51f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7B ABCA12 ABCA13 MUC5B MYO15A ST18

8.36e-0518417362cbed6462fea2622871bb7e49b0df3d984239281
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK2 CYP3A4 CLDN25 ITPR2 SYNE2 PLCB4

8.36e-051841736a60802e11dcc5f932811260b08a95a32f60f6b19
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK2 CYP3A4 CLDN25 ITPR2 SYNE2 PLCB4

8.36e-05184173639c230d32e4259bc784e0edfd9e2884c96898564
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MYO7B CCND1 RAB11FIP1 PTK2 BEND6 ST18

8.36e-051841736667846c422cfa27e949a24844a305df859cb6760
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK2 CYP3A4 CLDN25 ITPR2 SYNE2 PLCB4

8.36e-0518417362a2fb691cc9414ef5b06c26239d2da03d6d7e5c2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SESTD1 SPATA6L GRM7 NAALADL2 PIP5K1B MAPK4

8.36e-0518417368fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7B ABCA12 ABCA13 MUC5B MYO15A ST18

8.36e-051841736ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYO7B CCND1 RAB11FIP1 PTK2 BEND6 ST18

8.36e-051841736a6f8b42982ec0cf44b950a2cd9715d068eec4ecb
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7B ABCA12 ABCA13 MUC5B MYO15A ST18

8.36e-0518417362b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA13 TRAIP MUC5B ORC1 RECQL4 MAPK4

8.61e-05185173647c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC14 ABCA13 TAS1R3 CC2D1A ITPR2 ST18

8.61e-051851736686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ERBB2 SPATA6L NOL6 KIF12 NHSL1 MED26

8.61e-051851736636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANK2 NAALADL2 ITPR1 ITPR2 SLC9A3 PLCL1

8.61e-051851736898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

HECTD4 PTK2 ITPR2 PIP5K1B PLCB4 MED13

8.87e-051861736de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell3'_v3-blood-Hematopoietic_progenitors-Progenitor_Erythro-Mega|blood / Manually curated celltypes from each tissue

SLC40A1 IGSF10 GAL DLC1 KCNH2 PLCB4

8.87e-05186173659c115bbbb4bca4ad80be1809d8a0422b8438ea3
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

HECTD4 PTK2 ITPR2 PIP5K1B PLCB4 MED13

8.87e-0518617360b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANK2 ITPR1 ITPR2 SLC9A3 PLCL1 MAPK4

9.14e-051871736b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

PTK2 CSPG4 SYNE2 PIP5K1B PLCL1 KCNT1

9.68e-0518917369c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellmoderate-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ANK2 CYP3A4 CLDN25 ITPR2 KCNH2 PLCL1

9.68e-0518917366011b747e27d61d222380a7bffdd921a68e9b657
ToppCellPBMC-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

ATP7B POLA1 ORC1 TMEM106C UTP20 TIMELESS

9.68e-051891736946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCellcritical-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ANK2 CYP3A4 CLDN25 ITPR2 KCNH2 PLCL1

9.97e-05190173605a2c3549b68f49081723bf35db14974274419d5
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

SESTD1 RAB11FIP1 PTK2 MAPK8IP3 ANKRD13A TMEM156

9.97e-0519017361e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK2 MYO5A ARHGAP26 MCF2L2 IGSF10 GAL

1.09e-041931736a189d46c39067b717509cd144e0225cc93d7731d
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

SESTD1 MYCBP2 PTK2 ANKRD13A TMEM156 PIP5K1B

1.09e-0419317367ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBR4 KIF12 HID1 GFPT1 SF3B1 SEC23B

1.12e-0419417363a3ecedcdc7691cf21775818b598208fcb980c29
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 UBR4 KIF12 HID1 GFPT1 SEC23B

1.12e-0419417360b023de48ed8a550d169bbe954881eb04bf4f981
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

POLA1 ORC1 COMMD4 TMEM106C RECQL4 TIMELESS

1.15e-041951736cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

POLA1 MYO19 ORC1 TMEM106C RECQL4 TIMELESS

1.15e-041951736b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 CCDC30 ABCA13 KIF19 CFAP45 LRRC74B

1.15e-04195173679dc031258579ea328181dda33710dd897f1064a
ToppCell(1)_T_cells-(1)_T_cells_Dividing|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

POLA1 TRAIP ORC1 TMEM106C RECQL4 TIMELESS

1.15e-041951736cf00a0b4f341f0487d5b37810abe2952fdd3f6f2
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 SPATA6L CCDC30 IFT81 KIF19 CFAP45

1.15e-041951736e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

POLA1 MYO19 ORC1 TMEM106C RECQL4 TIMELESS

1.15e-04195173656d8734d020b3da08a5aa9e67999706a9e023a99
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

POLA1 ORC1 COMMD4 TMEM106C RECQL4 TIMELESS

1.18e-041961736df366d76ea55f49e349d622effa57c1535df8400
ToppCell3'_v3-Lung-Myeloid_Monocytic-Nonclassical_monocytes|Lung / Manually curated celltypes from each tissue

FFAR3 GPR42 CDH23 PFKFB3 PPM1F SYN1

1.18e-0419617367fe97109a5a06b35fc081a85f341ea78da131323
ToppCellmild-dn_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CCDC14 SESTD1 USP24 SIRPG SYNE2 ZBTB40

1.22e-04197173607a1f59c83b748825e0708cd1cc7b63a2cb856cc
ToppCellCOVID-19-COVID-19_Convalescent-Others-HSPC|COVID-19_Convalescent / Disease, condition lineage and cell class

ATP7B SLC40A1 IGSF10 DLC1 KCNH2 PIP5K1B

1.22e-041971736c1033a1a8b8b5c8569130aa9405a6e8e65ef7bd0
ToppCellSigmoid-B_cell-B_cell_IgG_Plasma|B_cell / Region, Cell class and subclass

CCPG1 FFAR3 PEX1 SRPRA TMEM156 MYBPC3

1.25e-041981736305d7ae9b070ac7211638a5282374c02bf13af40
ToppCellCOVID-19_Severe-T/NK_proliferative|World / disease group, cell group and cell class

POLA1 TRAIP ORC1 TMEM106C RECQL4 TIMELESS

1.25e-04198173648045689d0969ff0a14eee7086b8e19b0d6b6065
ToppCell(11)_FOXN4+|World / shred by cell type by condition

CCDC14 IFT81 MUC5B TMEM106C RECQL4 CFAP45

1.25e-041981736516b1acdf997dd8debc3dca066519366e507b414
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TRAIP ORC1 TMEM106C SYNE2 RECQL4 TIMELESS

1.28e-041991736101f78fe6dd1bf9e2e4dd5ad8a970312b3540927
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRAIP ORC1 TMEM106C SYNE2 RECQL4 TIMELESS

1.28e-041991736e0fcec796afe75e42467ca86355b9fc5aa9ae0a1
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP26 TBL1XR1 NAALADL2 PTK2 ITPR2 PLCB4

1.28e-04199173694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PRKD2 PTK2 DLC1 TIE1 SYNE2 PLCB4

1.32e-04200173672ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

ERBB2 CCND1 NAALADL2 CATSPER4 SYNE2 STRC

1.32e-0420017362dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PRKD2 PTK2 DLC1 TIE1 SYNE2 PLCB4

1.32e-0420017365c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

POLA1 TRAIP ORC1 TMEM106C RECQL4 TIMELESS

1.32e-04200173604bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH3 CCDC30 ABCA13 KIF19 CFAP45 LRRC74B

1.32e-042001736ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

POLA1 TRAIP ORC1 TMEM106C RECQL4 TIMELESS

1.32e-042001736f6b5320cdfe640a71e6e2df26f30d42e64b1c921
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

DNAH3 CCDC30 ABCA13 KIF19 CFAP45 LRRC74B

1.32e-042001736a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH3 CCDC30 ABCA13 KIF19 CFAP45 LRRC74B

1.32e-042001736918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nts|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KLHL1 RAB11FIP1 GAL CATSPER4 ST18

1.38e-041271735ace2944328529fa029ee56c7ad3b0f283511d3bb
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

UBR4 PFKFB3 CYP2G1P ZBTB40 HFM1

1.84e-0413517353351e8b9e417397c5fa9f856184ff24ce1a27242
Druggeldanamycin

ERBB2 IPO8 MYO5A SRPRA CCND1 FANCM LARP4 PTK2 DDX6 IQGAP1 APPL2 KCNH2 MED13

4.31e-0637116913ctd:C001277
Druggabapentin

CYP3A4 SLC40A1 GFPT1 ITPR1 ITPR3 KCNH2 PKD1 TIMELESS MAP2K5

5.00e-061691699CID000003446
Diseasepregnanediol-3-glucuronide measurement

SLC22A25 PUDP SLC22A24

9.08e-0681633EFO_0800341
Diseaseestrogen measurement

SLC22A25 SLC22A24 SLC22A9

1.93e-05101633EFO_0011007
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

3.03e-0521632DOID:0110471 (implicated_via_orthology)
DiseaseHypoxic Brain Damage

ITPR1 ITPR2

3.03e-0521632C1140716
DiseaseAnoxic Encephalopathy

ITPR1 ITPR2

3.03e-0521632C0003132
DiseaseBrain Hypoxia

ITPR1 ITPR2

3.03e-0521632C1527348
DiseaseAnoxia of brain

ITPR1 ITPR2

3.03e-0521632C0995195
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR2 ITPR3

3.51e-05121633DOID:1441 (implicated_via_orthology)
Diseaseconotruncal heart malformations, parental genotype effect measurement

SLC22A25 SLC22A24

9.07e-0531632EFO_0005939, MONDO_0016581
Disease17alpha-hydroxypregnanolone glucuronide measurement

SLC22A25 SLC22A24

9.07e-0531632EFO_0800363
DiseaseTorsades de Pointes

CYP3A4 KCNH2

9.07e-0531632C0040479
Diseasesensory system disease (implicated_via_orthology)

TBL1Y TBL1XR1

9.07e-0531632DOID:0050155 (implicated_via_orthology)
Diseaseandrosterone glucuronide measurement

SLC22A25 CYP3A4 SLC22A24

1.76e-04201633EFO_0800317
Diseasehormone measurement, progesterone measurement

SLC22A25 SLC22A24

3.00e-0451632EFO_0004730, EFO_0007004
DiseaseMalignant neoplasm of breast

ERBB2 ATP7B ANK2 CYP3A4 UBR4 MCF2L2 CCND1 GGA3 PHKB SLC22A9 PPM1F SYNE2 MROH7 UTP20 TIMELESS DOP1A

3.16e-04107416316C0006142
Diseaseepiandrosterone sulfate measurement

SLC22A25 CYP3A4 CYP3A43

3.48e-04251633EFO_0021120
DiseaseDwarfism

TRAIP FBXL3 ORC1

3.48e-04251633C0013336
Diseaseandrostenediol (3beta,17beta) monosulfate (1) measurement

PUDP CYP3A4

4.48e-0461632EFO_0800294
DiseaseColorectal Carcinoma

DNAH3 ATP7B ANK2 ABCA12 ABCA13 MCF2L2 CCND1 SLC22A9 DLC1 KCNA10 PPM1F VPS13A

5.55e-0470216312C0009402
Diseasedehydroepiandrosterone sulphate measurement

PUDP CYP3A4 ABCA13 CYP3A43

5.55e-04681634EFO_0007001
Diseaseesophageal carcinoma

IFT81 HECTD4 NAALADL2

6.02e-04301633EFO_0002916
Diseaselong QT syndrome (is_implicated_in)

ANK2 KCNH2

6.25e-0471632DOID:2843 (is_implicated_in)
Diseaseinvasive lobular carcinoma (is_marker_for)

ERBB2 CCND1

6.25e-0471632DOID:3457 (is_marker_for)
DiseaseMalignant Neoplasms

ERBB2 CCND1 SF3B1 DLC1 KCNH2

7.41e-041281635C0006826
DiseaseUveal melanoma

SF3B1 PLCB4

8.31e-0481632C0220633
DiseaseNonsyndromic genetic hearing loss

CISD2 CDH23 STRC MYO15A

8.45e-04761634cv:C5680182
DiseaseX-12844 measurement

SLC22A25 SLC22A24

1.06e-0391632EFO_0021339
Diseaseductal carcinoma in situ (is_marker_for)

ERBB2 CCND1 PTK2

1.31e-03391633DOID:0060074 (is_marker_for)
Diseaseinitial pursuit acceleration

IPO8 DNAAF5 PLCB4 MED13

1.40e-03871634EFO_0008434
Diseaseandrostenediol (3beta,17beta) monosulfate (2) measurement

PUDP CYP3A4

1.61e-03111632EFO_0800295
Diseasetestosterone measurement

FAM184B SLC22A25 ANK2 MYO5A CYP3A4 ARHGAP26 TRAIP SLC22A24 LARP4 DDX6 IQGAP1 GGA3 COMMD4 FAM186A SYNE2 MYO15A

1.93e-03127516316EFO_0004908
Diseasemethionine sulfone measurement

CYP3A4 CYP3A43

1.93e-03121632EFO_0800072
Diseasemismatch repair cancer syndrome (is_implicated_in)

ASTE1 SLC22A9

1.93e-03121632DOID:0112182 (is_implicated_in)
Disease11beta-hydroxyandrosterone glucuronide measurement

SLC22A25 SLC22A24

1.93e-03121632EFO_0800573
DiseasePapilloma

ERBB2 CCND1

1.93e-03121632C0030354
DiseasePapillomatosis

ERBB2 CCND1

1.93e-03121632C0205875
DiseasePapilloma, Squamous Cell

ERBB2 CCND1

1.93e-03121632C0205874
Diseaseuric acid measurement

PRKD2 SESTD1 DNAH3 ARHGAP26 IFT81 HECTD4 SLC22A24 COMMD4 PIP5K1B HFM1

2.17e-0361016310EFO_0004761
Disease5alpha-pregnan-3beta,20beta-diol monosulfate (1) measurement

PUDP CYP3A4

2.27e-03131632EFO_0800284
DiseaseProstatic Neoplasms

REC8 ERBB2 ATP7B CYP3A4 CYP3A43 CCND1 TBL1XR1 ITPR1 SF3B1 APPL2

2.33e-0361616310C0033578
DiseaseMalignant neoplasm of prostate

REC8 ERBB2 ATP7B CYP3A4 CYP3A43 CCND1 TBL1XR1 ITPR1 SF3B1 APPL2

2.33e-0361616310C0376358
DiseaseMajor Depressive Disorder

ATP7B CC2D1A CCND1 PFKFB3 GRM7 GAL

2.38e-032431636C1269683
Diseasespontaneous preterm birth

KLHL1 PFKFB3 NHSL1 DLC1

2.42e-031011634EFO_0006917
Diseasetrimethylamine-N-oxide measurement

ITPR2 ST18

2.64e-03141632EFO_0010541
Diseaseresponse to cisplatin

HTATIP2 NHSL1 MAPK4

2.84e-03511633GO_0072718
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

CDH23 STRC MYO15A

2.84e-03511633cv:CN043650
DiseaseC-reactive protein measurement

ZSWIM8 CYP3A4 TRAIP HID1 TBL1XR1 DDX6 MAPK8IP3 ITPR1 PKD1 CFAP45 OASL ZBTB40 HFM1 MAPK6 MYBPC3

2.90e-03120616315EFO_0004458
Diseasehyperinsulinism (biomarker_via_orthology)

PFKFB1 GFPT1

3.04e-03151632DOID:2018 (biomarker_via_orthology)
Diseasetumor necrosis factor beta measurement

NAALADL2 ZBTB40

3.04e-03151632EFO_0008308
Diseaseobsolete_red blood cell distribution width

MYO19 HECTD4 CDH23 TBL1XR1 SLC40A1 PTK2 IQGAP1 ARPC2 GAL NPRL2 TMEM259 SYNE2 VPS13A ZBTB40 HFM1 SEC23B

3.32e-03134716316EFO_0005192
DiseaseRomano-Ward Syndrome

ANK2 KCNH2

3.46e-03161632C0035828
DiseaseChronic Lymphocytic Leukemia

PRKD2 CCND1 SF3B1

3.52e-03551633C0023434
Diseaselysophosphatidylcholine 18:1 measurement

MPHOSPH10 ST18

3.91e-03171632EFO_0010360
Diseaseurate measurement

PRKD2 DNAH3 CYP3A4 MSANTD5 TRAIP RAB11FIP2 HECTD4 COMMD4 CSPG4 PIP5K1B HFM1 GJA10

4.21e-0389516312EFO_0004531
Diseaseneutrophil count

SPATA6L MYCBP2 ARHGAP26 HECTD4 CDH23 ITPR2 ARPC2 ANKRD13A TIE1 FAM186A PKD1 CFAP45 PLCB4 PLCL1 MAPK4 MAP2K5

4.25e-03138216316EFO_0004833
Diseasebirth weight, parental genotype effect measurement

CYP3A4 KIF12 CCND1 IQGAP1 ITPR2

4.36e-031921635EFO_0004344, EFO_0005939
Diseasemetabolonic lactone sulfate measurement

CYP3A4 CYP3A43

4.88e-03191632EFO_0800659
DiseaseChronic myeloproliferative disorder

TRAIP ORC1

4.88e-03191632C1292778
Diseasediet measurement, HOMA-B

KLHL1 RAB11FIP2

4.88e-03191632EFO_0004469, EFO_0008111
Diseaseage at onset, smoking initiation

MYCBP2 ITPR2

4.88e-03191632EFO_0004847, EFO_0005670
Diseaseetiocholanolone glucuronide measurement

CYP3A4 SLC22A24

4.88e-03191632EFO_0800362
DiseaseBipolar Disorder

ABCA13 PFKFB3 GRM7 FBXL3 ITPR1 GAL TIMELESS BRD1

5.18e-034771638C0005586

Protein segments in the cluster

PeptideGeneStartEntry
EPVIMELERQENVLV

PFKFB1

376

P16118
TMRRLLQETELVEPL

ERBB2

686

P04626
LLVERLGMTPAQIQA

EOLA1

56

Q8TE69
LLVERLGMTPAQIQA

EOLA2

56

Q96DE9
QAMVIVPTRELALQV

DDX6

166

P26196
EQVAMELRLTPLTVL

BRD1

556

O95696
ARIIRVILQSVPDMA

CATSPER4

201

Q7RTX7
DQLVLEVSVTARVPM

CSPG4

516

Q6UVK1
DNLIIREEQVPMELV

ATP7B

811

P35670
LENITQLIPIIEAML

ABCA12

526

Q86UK0
MILLEVNNRIIEETL

ARPC2

1

O15144
VRQAALPIMELSQEL

GJA10

481

Q969M2
LSLPQELQVARILMV

CLDN25

71

C9JDP6
PLQDMIERAIILVQT

ABCA13

3526

Q86UQ4
LQRLIVLEHRVMTIP

DOP1A

1586

Q5JWR5
SIRPEELLQMELLLV

CCND1

131

P24385
VNLRPVVQLIDIMKD

AHDC1

116

Q5TGY3
LSELRPVTIVFVNLM

ADCY10

286

Q96PN6
ALLQAQVVMRIVDPE

CSTF2

171

P33240
QVVMRIVDPEIALKI

CSTF2

176

P33240
MLLVEVIDVNDNRPV

CDH23

2596

Q9H251
IQVEIALAMQPLRSE

CCDC14

476

Q49A88
LVLRRTILPTQVENM

ASTE1

346

Q2TB18
LRQSLVMLQVLPQAV

BEND6

91

Q5SZJ8
TVLPLVMDIQLLGQR

ALG1L

151

Q6GMV1
NALRQILAPVVKEIM

IQGAP1

1066

P46940
LLVQLVPLMQVFVRL

MUC5B

536

Q9HC84
FVELLQMEQVRRIPE

MROH7

986

Q68CQ1
QAMEEQLVSTLVPLL

MROH7

1121

Q68CQ1
MEIVILPTETTINIQ

MSANTD5

1

A0A3B3IT52
TLFDLVVPMILQQRA

RAB20

196

Q9NX57
RAQLQIRIDMETELP

REC8

101

O95072
SERERLLPVINTMLQ

RGPD5

1726

Q99666
SERERLLPVINTMLQ

RGPD8

1726

O14715
TRTLLAILDIVQAPM

ITPR2

886

Q14571
IVRQDRSMEQIVFPV

ITPR3

2126

Q14573
VHLMETNTEPLQERI

ANK2

3646

Q01484
EQVIPIIDLMARTSA

ANKRD13A

376

Q8IZ07
PVEEIQIIHMERLLI

DDI1

41

Q8WTU0
TIPAALLDRMEIIQV

LONP2

496

Q86WA8
VPVVTVVRAMLNNVV

HTATIP2

201

Q9BUP3
VVKELMPLVVNVLEN

MAPK8IP3

51

Q9UPT6
MPLVVNVLENLDSVL

MAPK8IP3

56

Q9UPT6
IVRLDRTMEQIVFPV

ITPR1

2206

Q14643
VMQQIKILEATPLLE

MYO15A

1341

Q9UKN7
PEDVLLEMVQIRTIR

MYO19

341

Q96H55
EAAQIIIDVLQLPMS

PUDP

56

Q08623
EQMQLILETIPVIRE

MAPK4

236

P31152
IQVVLRVRPMSAAEL

KIF12

26

Q96FN5
PEMQEVLLEVQRLRV

FAM184B

191

Q9ULE4
EIAEMLSQHQPIIRV

FANCM

491

Q8IYD8
TEMDVQVRRVLQIPL

KCNT1

391

Q5JUK3
ATVLQLLQRQMTLVP

KCNH2

1061

Q12809
PETIQLITRDMVREL

CFAP45

76

Q9UL16
LDMVVNETLRLFPIA

CYP3A4

356

P08684
LITTEALQMVQLRPV

NHSL1

1071

Q5SYE7
QEVRPLMAVEIIEQL

MCF2L2

31

Q86YR7
IDVITMQTLVLLVDL

GPR26

206

Q8NDV2
AMENQVLVIRIKIPN

MAP2K5

11

Q13163
HELEQMQLILESIPV

MAPK6

236

Q16659
LVQTEEMQPVVFVLL

OR3A2

26

P47893
LVQTEEMQPVVFVLL

OR3A3

26

P47888
INIRIVVMNNVLPRS

PIP5K1B

181

O14986
EPVIMELERQENVLV

PFKFB3

371

Q16875
VQLVTELRMTRAIQP

HACE1

741

Q8IYU2
INVDVALTMPREILQ

NOL6

176

Q9H6R4
ETAIRQALMPVILQD

PRKD2

501

Q9BZL6
VRMAPVITEETTLQL

MPHOSPH10

411

O00566
RPDVLVVVVSMLNTA

GGA3

621

Q9NZ52
LVEIILHVVRQMTDP

PSMD13

76

Q9UNM6
VFVANPLQERTILMR

HECTD4

56

Q9Y4D8
DQLAILLPVRLEMAV

GPR42

176

O15529
PQSNIRNMVAVLEVI

MED26

21

O95402
ELSLLLQVEQRMPVS

MLKL

111

Q8NB16
LSIVSEIQPQMLVEL

DQX1

656

Q8TE96
LVQQILKTERVVIPM

POLA1

711

P09884
ISIAQIRETPMVLEL

MTERF2

311

Q49AM1
MVLELTPQIVQYRIR

MTERF2

321

Q49AM1
LRMEQRVPDALVFTI

OASL

126

Q15646
VVFELAITRLLMEVP

HFM1

311

A2PYH4
QLMVALRVRPISVAE

KIF19

11

Q2TAC6
IVLLLTVLFRMQAQP

ACP2

396

P11117
LQRMVLVDLPGVINT

OPA1

391

O60313
RLVVLAIANTMDLPE

ORC1

646

Q13415
RNIMNIIDIISIIPY

KCNA10

301

Q16322
TIMEVQRLTVVVPLA

CYP2U1

406

Q7Z449
TVVNPIRMDEFRQII

CCPG1

646

Q9ULG6
ESVLVVQLEVLEMLR

IGSF10

2321

Q6WRI0
PMQLLQVLSDVLAEI

IFT81

31

Q8WYA0
LDMVVNETLRLFPVV

CYP3A43

356

Q9HB55
QLIMIKLEVSEPIIV

DNAH3

486

Q8TD57
RLSQLSIMEEVLIPD

FBXL3

386

Q9UKT7
IPENNIMRTIIEFLS

GAL

81

P22466
VQSLAQNPRLRMIVE

CRAMP1

336

Q96RY5
DQLAILLPVRLEMAV

FFAR3

176

O14843
VMVRIREPLTAQQLE

CC2D1A

786

Q6P1N0
QQLTMKPEEIVRLRE

CCDC30

186

Q5VVM6
VKIVMLVNENPLLTE

ANKMY2

176

Q8IV38
QLADTMVLPIIQFRE

APPL2

106

Q8NEU8
LLQSVEEPMVHLRLE

COMMD4

146

Q9H0A8
DLILEVLRSSPMVQV

LARP4

171

Q71RC2
LPAILQQVRIQEMLL

TMEM259

451

Q4ZIN3
VSIMVANILRLFQIP

GRM7

161

Q14831
RDVQETLMPQVLTTL

DNAAF5

696

Q86Y56
PVINNLIQMILAEIE

FAM186A

786

A6NE01
LAIIFVPQEMQTLRV

SLC22A25

421

Q6T423
VPQEMQTLRVVLATL

SLC22A25

426

Q6T423
RLNIEMHAVVRITPV

PEX1

421

O43933
ELLMVVSIVLERNPE

PHKB

1001

Q93100
VNQTLRILVVSRNPM

LRRC74B

301

Q6ZQY2
VDVVLPLQVLMRRSQ

PKD1

2151

P98161
ITVMVVFLRDPQELL

PPM1F

406

P49593
RPIMQELLHIVRETE

IPO8

541

O15397
QIRESLLQIPRIEMK

OR52M1

301

Q8NGK5
RRLTQLSVMEEVLIP

FBXL21P

391

Q9UKT6
ATVEQVLDPRTRMIL

RIOK1

156

Q9BRS2
LRQELLAMIPIDQIL

RTL1

1046

A6NKG5
DPLLILSQIVLMQTV

SYS1

11

Q8N2H4
IVELVVNKMAQALPR

SYN1

406

P17600
VPEILVHNIVIFMRT

TMEM106C

206

Q9BVX2
LTTEVMQIRDFLPRI

HSF2BP

31

O75031
PLLDLVVQLARDLQM

UTP20

106

O75691
DNLLVRVMEETPNIL

RAB11FIP1

1256

Q6WKZ4
RVMEETPNILRIPTQ

RAB11FIP1

1261

Q6WKZ4
MPLEVVVELQIRAIS

SPATA6L

1

Q8N4H0
IELIPQVRIEDLKQM

PLCB4

911

Q15147
LLQSSEIPLELQVME

SYNE2

1706

Q8WXH0
EIPLELQVMESSILN

SYNE2

1711

Q8WXH0
FQLMVQESETLIIPR

SYNE2

2846

Q8WXH0
LMQLEKELVERQPQV

SYNE2

6706

Q8WXH0
LPQEMQILRVVLATL

SLC22A24

426

Q8N4F4
ATRQVLEELTELPVM

GFPT1

401

Q06210
NLVIIRTLLMQPVQQ

PTAFR

206

P25105
ERALPIQLTVQALDM

RECQL4

901

O94761
LLAIIFVPQEMQTLR

SLC22A9

421

Q8IVM8
ISELLTPLQAELMRI

PRAMEF19

426

Q5SWL8
QVLPTHLMEERLIRQ

PTK2

801

Q05397
TIMRLLQVLVPQVEK

HID1

696

Q8IV36
RVISELLTPLQAELM

PRAMEF22

426

A3QJZ6
YRMVQLEPIDQVVLS

SLC9A3

396

P48764
RIRMIENASEVLITP

ARHGAP26

101

Q9UNA1
TIRRIDQLTNILAPM

SLC40A1

176

Q9NP59
VLEKMLVIVVLPVRN

MYCBP2

1661

O75592
QDILRMLLSLQPVLQ

MED13

1276

Q9UHV7
QKLVPIMTILLEELN

NPRL2

126

Q8WTW4
ELQMIQPEKLLLVTV

SIRPG

31

Q9P1W8
MLLPDENREVLQTLL

DLC1

1191

Q96QB1
SIMLVVELVQRAPEQ

STRC

1276

Q7RTU9
LSLIDAVMPDVVQTR

TBL1XR1

81

Q9BZK7
RQDLTQSLIMIQPIL

SEC23B

611

Q15437
VVMLQNVVPAEVSLV

SESTD1

81

Q86VW0
VRVPLEILAMHENVL

ST18

396

O60284
VVIHEIQRLVDIVPM

CYP2G1P

6

Q6ZSU1
MVLESVARIVKVQLP

CISD2

1

Q8N5K1
LQPVRETQIIMRIFL

TMEM156

61

Q8N614
MVALQIAREPLVRQV

SUPT6H

591

Q7KZ85
AVIRLMVNLTQPALL

TIMELESS

81

Q9UNS1
VNLPELAMIRFVVLD

PLCL1

786

Q15111
LLANVQVVLRPAVQM

TAS1R3

781

Q7RTX0
RMALDINIKAPVVVI

VPS13A

1206

Q96RL7
TREVMLILIREFQSP

SF3B1

766

O75533
IVVDPSENVTLMNLR

TIE1

496

P35590
LEPMERILEHIQILA

ZNF75CP

166

Q92670
ESLVQILQPQRRVDM

SRPRA

391

P08240
IDNLLVRVMEETPSI

RAB11FIP2

481

Q7L804
LSLIVAVIPDVVQMR

TBL1Y

81

Q9BQ87
VLQEIVMETLQRLSP

ZSWIM8

1731

A7E2V4
IIPAARVAIQTMEVS

USP24

1311

Q9UPU5
SILERLLQAMEPVHV

PSMD5

66

Q16401
ESIMLVVELVQRAPE

STRCP1

1276

A6NGW2
IQRLIDSVPLMNLLL

UBR4

521

Q5T4S7
LNVALRVPSIMLLDV

RNF145

11

Q96MT1
VDLVLELAPMSVLRV

PRR23C

76

Q6ZRP0
PMNVKNVVELLTIVQ

ZNF781

256

Q8N8C0
LIQCVTQLRPIMESL

ZBTB40

361

Q9NUA8
ETAPQLTLVLAIMLQ

XKR8

141

Q9H6D3
MEQIELLLQSQRPEV

TRAIP

166

Q9BWF2
LLLQSQRPEVEEMIR

TRAIP

171

Q9BWF2
IMEVIRNQEFLLLPA

KLHL1

341

Q9NR64
LDRMVVLLSVTVQQP

MXRA5

1936

Q9NR99
EARLILQLTVLEPME

MXRA5

2526

Q9NR99
LELPNNEIRVVSMQV

NAALADL2

406

Q58DX5
QQLVRVLENILQPMI

MYO5A

1611

Q9Y4I1
ILRELVPENLTRLMS

MYO7B

1956

Q6PIF6
ITRPLEDQLVMVGQR

MYBPC3

456

Q14896