Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionandrosterone dehydrogenase (B-specific) activity

AKR1C1 AKR1C2 AKR1C3

7.22e-0741143GO:0047042
GeneOntologyMolecularFunctionketoreductase activity

AKR1C1 AKR1C2 AKR1C3

7.22e-0741143GO:0045703
GeneOntologyMolecularFunctionchlordecone reductase activity

AKR1C1 AKR1C2 AKR1C3

7.22e-0741143GO:0047743
GeneOntologyMolecularFunctiontrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

1.80e-0651143GO:0047115
GeneOntologyMolecularFunction15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity

AKR1C1 AKR1C2 AKR1C3

1.80e-0651143GO:0047020
GeneOntologyMolecularFunction17-beta-ketosteroid reductase (NADPH) activity

AKR1C1 AKR1C2 AKR1C3

1.80e-0651143GO:0072555
GeneOntologyMolecularFunction17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

1.80e-0651143GO:0047006
GeneOntologyMolecularFunctionlithocholic acid binding

AKR1C1 AKR1C2 AKR1C3

1.80e-0651143GO:1902121
GeneOntologyMolecularFunctionketosteroid monooxygenase activity

AKR1C1 AKR1C2 AKR1C3

1.80e-0651143GO:0047086
GeneOntologyMolecularFunctionDelta4-3-oxosteroid 5beta-reductase activity

AKR1C1 AKR1C2 AKR1C3

1.80e-0651143GO:0047787
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1C1 AKR1C2 AKR1C3

3.58e-0661143GO:0045550
GeneOntologyMolecularFunction17-beta-hydroxysteroid dehydrogenase (NADP+) activity

AKR1C1 AKR1C2 AKR1C3

6.24e-0671143GO:0072582
GeneOntologyMolecularFunction5alpha-androstane-3beta,17beta-diol dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

9.94e-0681143GO:0047024
GeneOntologyMolecularFunctionandrosterone dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

9.94e-0681143GO:0047023
GeneOntologyMolecularFunctionenone reductase activity

AKR1C1 AKR1C2 AKR1C3

9.94e-0681143GO:0035671
GeneOntologyMolecularFunctionandrostan-3-alpha,17-beta-diol dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

1.48e-0591143GO:0047044
GeneOntologyMolecularFunctionNADP+ binding

AKR1C1 AKR1C2 AKR1C3

1.48e-0591143GO:0070401
GeneOntologyMolecularFunctiontestosterone 17-beta-dehydrogenase (NADP+) activity

AKR1C1 AKR1C2 AKR1C3

2.11e-05101143GO:0047045
GeneOntologyMolecularFunctionbile acid binding

AKR1C1 AKR1C2 AKR1C3

2.11e-05101143GO:0032052
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1C1 AKR1C2 AKR1C3

6.30e-05141143GO:0004032
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

6.30e-05141143GO:0001758
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

MRE11 SETX ERCC6L SMARCAL1 RFC1 DNA2

8.95e-051271146GO:0008094
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

KDM4C CYP11A1 AKR1C1 AKR1C2 TYR AKR1C3 KDM2A

1.26e-041941147GO:0016705
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

MRE11 EXO5 SETX ERCC6L SMARCAL1 RFC1 POLG2 DNA2

1.31e-042621148GO:0140097
GeneOntologyMolecularFunctionindanol dehydrogenase activity

AKR1C1 AKR1C2

1.92e-0441142GO:0047718
GeneOntologyMolecularFunctionestradiol 17-beta-dehydrogenase [NAD(P)+] activity

AKR1C1 AKR1C2 AKR1C3

1.92e-04201143GO:0004303
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

AKR1C1 AKR1C2 AKR1C3

3.36e-04241143GO:0004745
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

AKR1C1 AKR1C2 AKR1C3

4.28e-04261143GO:0004022
GeneOntologyMolecularFunctionNADPH binding

AKR1C1 AKR1C2 AKR1C3

4.28e-04261143GO:0070402
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

AKR1C1 AKR1C2 AKR1C3

4.80e-04271143GO:0008106
GeneOntologyMolecularFunctionmonooxygenase activity

CYP11A1 AKR1C1 AKR1C2 TYR AKR1C3

5.17e-041151145GO:0004497
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

AKR1C1 AKR1C2 AKR1C3

6.58e-04301143GO:0018455
GeneOntologyMolecularFunctionnucleocytoplasmic carrier activity

KPNA4 TNPO1 XPO6

7.97e-04321143GO:0140142
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

AKR1C1 AKR1C2 AKR1C3

7.97e-04321143GO:0004033
GeneOntologyMolecularFunctionsteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1C1 AKR1C2 AKR1C3

8.73e-04331143GO:0033764
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

AKR1C1 AKR1C2 AKR1C3

9.53e-04341143GO:0016628
GeneOntologyMolecularFunctionsteroid dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

1.43e-03391143GO:0016229
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

AKR1C1 AKR1C2 AKR1C3

1.54e-03401143GO:0016709
GeneOntologyMolecularFunctionhistone H3K36 demethylase activity

KDM4C KDM2A

1.72e-03111142GO:0051864
GeneOntologyMolecularFunctiontestosterone dehydrogenase [NAD(P)+] activity

AKR1C1 AKR1C3

1.72e-03111142GO:0030283
GeneOntologyMolecularFunctionhelicase activity

MRE11 SETX ERCC6L SMARCAL1 DNA2

2.14e-031581145GO:0004386
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

AKR1C1 AKR1C2 AKR1C3

2.60e-03481143GO:0016620
GeneOntologyMolecularFunctionATP-dependent activity

MRE11 SETX ERCC6L SMARCAL1 PSMC1 RNF213 RFC1 UBA6 DNA2 KIF2C

2.72e-0361411410GO:0140657
GeneOntologyMolecularFunction3'-5'-DNA exonuclease activity

MRE11 EXO5

3.68e-03161142GO:0008296
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors

AKR1C1 AKR1C2 AKR1C3

4.03e-03561143GO:0016903
GeneOntologyMolecularFunctionlipid binding

HIP1 ANKFY1 CYP11A1 RUBCNL F3 AKR1C1 AKR1C2 MAP3K1 ITPR1 SNX14 AKR1C3 BAIAP3 MITD1

4.18e-0398811413GO:0008289
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

AKR1C1 AKR1C2 AKR1C3

4.90e-03601143GO:0016655
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

TRERF1 KDM4C ZMIZ2

5.13e-03611143GO:0030374
GeneOntologyMolecularFunctionDNA helicase activity

MRE11 SETX DNA2

5.37e-03621143GO:0003678
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors

AKR1C1 AKR1C2 AKR1C3

5.37e-03621143GO:0016627
GeneOntologyMolecularFunctionNADP binding

AKR1C1 AKR1C2 AKR1C3

5.37e-03621143GO:0050661
GeneOntologyMolecularFunctionnuclear import signal receptor activity

KPNA4 TNPO1

5.74e-03201142GO:0061608
GeneOntologyBiologicalProcessregulation of testosterone biosynthetic process

AKR1C1 AKR1C2 AKR1C3 PRKG1

2.94e-07111154GO:2000224
GeneOntologyBiologicalProcessresponse to jasmonic acid

AKR1C1 AKR1C2 AKR1C3

6.73e-0741153GO:0009753
GeneOntologyBiologicalProcessprogesterone catabolic process

AKR1C1 AKR1C2 AKR1C3

6.73e-0741153GO:0006709
GeneOntologyBiologicalProcesscellular response to jasmonic acid stimulus

AKR1C1 AKR1C2 AKR1C3

6.73e-0741153GO:0071395
GeneOntologyBiologicalProcessC21-steroid hormone catabolic process

AKR1C1 AKR1C2 AKR1C3

6.73e-0741153GO:0008208
GeneOntologyBiologicalProcesstestosterone biosynthetic process

AKR1C1 AKR1C2 AKR1C3 PRKG1

1.58e-06161154GO:0061370
GeneOntologyBiologicalProcessfarnesol metabolic process

AKR1C1 AKR1C2 AKR1C3

1.67e-0651153GO:0016487
GeneOntologyBiologicalProcessfarnesol catabolic process

AKR1C1 AKR1C2 AKR1C3

1.67e-0651153GO:0016488
GeneOntologyBiologicalProcessnegative regulation of isoprenoid metabolic process

AKR1C1 AKR1C2 AKR1C3

1.67e-0651153GO:0045827
GeneOntologyBiologicalProcesssesquiterpenoid catabolic process

AKR1C1 AKR1C2 AKR1C3

1.67e-0651153GO:0016107
GeneOntologyBiologicalProcessolefinic compound catabolic process

AKR1C1 AKR1C2 AKR1C3

1.67e-0651153GO:0120256
GeneOntologyBiologicalProcessnegative regulation of retinoic acid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

1.67e-0651153GO:1900053
GeneOntologyBiologicalProcesssesquiterpenoid metabolic process

AKR1C1 AKR1C2 AKR1C3

3.34e-0661153GO:0006714
GeneOntologyBiologicalProcesspolyprenol catabolic process

AKR1C1 AKR1C2 AKR1C3

3.34e-0661153GO:0016095
GeneOntologyBiologicalProcessresponse to prostaglandin D

AKR1C1 AKR1C2 AKR1C3

5.81e-0671153GO:0071798
GeneOntologyBiologicalProcesscellular response to prostaglandin D stimulus

AKR1C1 AKR1C2 AKR1C3

5.81e-0671153GO:0071799
GeneOntologyBiologicalProcessregulation of retinoic acid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

5.81e-0671153GO:1900052
GeneOntologyBiologicalProcesstertiary alcohol metabolic process

CYP11A1 AKR1C1 AKR1C2 AKR1C3

6.21e-06221154GO:1902644
GeneOntologyBiologicalProcessregulation of ketone biosynthetic process

AKR1C1 AKR1C2 AKR1C3 PRKG1

1.25e-05261154GO:0010566
GeneOntologyBiologicalProcessdaunorubicin metabolic process

AKR1C1 AKR1C2 AKR1C3

1.38e-0591153GO:0044597
GeneOntologyBiologicalProcesspolyprenol metabolic process

MPDU1 AKR1C1 AKR1C2 AKR1C3

1.96e-05291154GO:0016093
GeneOntologyBiologicalProcessdoxorubicin metabolic process

AKR1C1 AKR1C2 AKR1C3

1.97e-05101153GO:0044598
GeneOntologyBiologicalProcessregulation of isoprenoid metabolic process

AKR1C1 AKR1C2 AKR1C3

1.97e-05101153GO:0019747
GeneOntologyBiologicalProcessnegative regulation of vitamin metabolic process

AKR1C1 AKR1C2 AKR1C3

1.97e-05101153GO:0046137
GeneOntologyBiologicalProcesspolyketide metabolic process

AKR1C1 AKR1C2 AKR1C3

1.97e-05101153GO:0030638
GeneOntologyBiologicalProcessaminoglycoside antibiotic metabolic process

AKR1C1 AKR1C2 AKR1C3

1.97e-05101153GO:0030647
GeneOntologyBiologicalProcessterpenoid catabolic process

AKR1C1 AKR1C2 AKR1C3

2.70e-05111153GO:0016115
GeneOntologyBiologicalProcessolefinic compound biosynthetic process

AKR1C1 AKR1C2 AKR1C3 PRKG1

4.20e-05351154GO:0120255
GeneOntologyBiologicalProcessretinoic acid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

5.88e-05141153GO:0002138
GeneOntologyBiologicalProcessisoprenoid catabolic process

AKR1C1 AKR1C2 AKR1C3

5.88e-05141153GO:0008300
GeneOntologyBiologicalProcessditerpenoid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

7.32e-05151153GO:0016102
GeneOntologyBiologicalProcessmitotic cell cycle process

CCNJL EXOC6 MRE11 MBTPS1 KAT5 CKAP5 NCAPG2 FANCD2 BUB1 DNA2 PCID2 MITD1 LCMT1 KIF2C KCNH5

8.04e-0585411515GO:1903047
GeneOntologyBiologicalProcessnegative regulation of hormone metabolic process

AKR1C1 AKR1C2 AKR1C3

8.97e-05161153GO:0032351
GeneOntologyBiologicalProcessC21-steroid hormone metabolic process

CYP11A1 AKR1C1 AKR1C2 AKR1C3

1.15e-04451154GO:0008207
GeneOntologyBiologicalProcessregulation of chromosome segregation

KAT5 NCAPG2 BUB1 PCID2 LCMT1 KIF2C

1.30e-041391156GO:0051983
GeneOntologyBiologicalProcessregulation of vitamin metabolic process

AKR1C1 AKR1C2 AKR1C3

1.30e-04181153GO:0030656
GeneOntologyBiologicalProcesshormone catabolic process

AKR1C1 AKR1C2 AKR1C3

2.09e-04211153GO:0042447
GeneOntologyBiologicalProcessterpenoid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

2.09e-04211153GO:0016114
GeneOntologyBiologicalProcessregulation of retinoic acid receptor signaling pathway

AKR1C1 AKR1C2 AKR1C3

2.09e-04211153GO:0048385
GeneOntologyBiologicalProcessretinal metabolic process

AKR1C1 AKR1C2 AKR1C3

2.09e-04211153GO:0042574
GeneOntologyBiologicalProcessketone catabolic process

AKR1C1 AKR1C2 AKR1C3

2.09e-04211153GO:0042182
GeneOntologyBiologicalProcesscell cycle checkpoint signaling

MRE11 MBTPS1 FANCD2 BUB1 DNA2 PCID2 LCMT1

2.17e-042171157GO:0000075
GeneOntologyBiologicalProcessparturition

AKR1C1 AKR1C2 AKR1C3

2.41e-04221153GO:0007567
GeneOntologyBiologicalProcessglycoside metabolic process

AKR1C1 AKR1C2 AKR1C3

2.41e-04221153GO:0016137
GeneOntologyBiologicalProcessprogesterone metabolic process

AKR1C1 AKR1C2 AKR1C3

2.41e-04221153GO:0042448
GeneOntologyBiologicalProcesscellular response to prostaglandin stimulus

AKR1C1 AKR1C2 AKR1C3

2.76e-04231153GO:0071379
GeneOntologyBiologicalProcessprimary alcohol catabolic process

AKR1C1 AKR1C2 AKR1C3

2.76e-04231153GO:0034310
GeneOntologyBiologicalProcessketone biosynthetic process

AKR1C1 AKR1C2 AKR1C3 PRKG1

2.88e-04571154GO:0042181
GeneOntologyBiologicalProcessestablishment or maintenance of microtubule cytoskeleton polarity

CKAP5 KIF2C

3.05e-0451152GO:0030951
GeneOntologyBiologicalProcessmitotic cell cycle checkpoint signaling

MRE11 MBTPS1 FANCD2 BUB1 PCID2 LCMT1

3.07e-041631156GO:0007093
GeneOntologyBiologicalProcessregulation of steroid biosynthetic process

MBTPS1 AKR1C1 AKR1C2 AKR1C3 PRKG1

3.20e-041061155GO:0050810
GeneOntologyBiologicalProcessregulation of mitotic sister chromatid segregation

KAT5 BUB1 PCID2 LCMT1

3.51e-04601154GO:0033047
GeneOntologyBiologicalProcessregulation of neurotransmitter receptor localization to postsynaptic specialization membrane

IQSEC2 MAGI2 KIF2C

3.55e-04251153GO:0098696
GeneOntologyBiologicalProcesschromosome organization

MRE11 SETX KAT5 SMARCAL1 RFC1 NCAPG2 FANCD2 BUB1 DNA2 PCID2 LCMT1 KIF2C

4.50e-0468611512GO:0051276
GeneOntologyBiologicalProcessDNA-templated DNA replication

MRE11 LRWD1 SMARCAL1 RFC1 POLG2 DNA2

4.91e-041781156GO:0006261
GeneOntologyBiologicalProcessnegative regulation of mRNA splicing, via spliceosome

AKR1C1 AKR1C2 AKR1C3

5.00e-04281153GO:0048025
GeneOntologyBiologicalProcessmitotic cell cycle

CCNJL EXOC6 MRE11 MBTPS1 KAT5 CKAP5 NCAPG2 FANCD2 BUB1 DNA2 PCID2 MITD1 LCMT1 KIF2C KCNH5

5.12e-04101411515GO:0000278
GeneOntologyBiologicalProcesssecondary metabolic process

AKR1C1 AKR1C2 TYR AKR1C3

5.36e-04671154GO:0019748
GeneOntologyBiologicalProcessnegative regulation of mRNA processing

AKR1C1 AKR1C2 AKR1C3

5.55e-04291153GO:0050686
GeneOntologyBiologicalProcesspositive regulation of endothelial cell apoptotic process

AKR1C1 AKR1C2 AKR1C3

7.44e-04321153GO:2000353
GeneOntologyBiologicalProcessnegative regulation of RNA splicing

AKR1C1 AKR1C2 AKR1C3

8.15e-04331153GO:0033119
GeneOntologyBiologicalProcesspositive regulation of platelet-derived growth factor receptor signaling pathway

HIP1 F3

8.44e-0481152GO:0010641
GeneOntologyBiologicalProcessnuclear chromosome segregation

MRE11 KAT5 NCAPG2 FANCD2 BUB1 PCID2 LCMT1 KIF2C

8.67e-043561158GO:0098813
GeneOntologyBiologicalProcesssteroid catabolic process

AKR1C1 AKR1C2 AKR1C3

8.91e-04341153GO:0006706
GeneOntologyBiologicalProcessprotein localization to cilium

ZNF423 TTC21A CCDC66 INVS

9.07e-04771154GO:0061512
GeneOntologyBiologicalProcessregulation of steroid metabolic process

MBTPS1 AKR1C1 AKR1C2 AKR1C3 PRKG1

9.62e-041351155GO:0019218
GeneOntologyBiologicalProcessregulation of chromosome separation

NCAPG2 BUB1 PCID2 LCMT1

9.99e-04791154GO:1905818
GeneOntologyBiologicalProcessDNA repair

MRE11 EXO5 SETX KAT5 SMARCAL1 RFC1 FANCD2 KDM2A TAF6 POLG2 DNA2

1.00e-0364811511GO:0006281
GeneOntologyBiologicalProcessresponse to prostaglandin

AKR1C1 AKR1C2 AKR1C3

1.05e-03361153GO:0034694
GeneOntologyBiologicalProcessisoprenoid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

1.05e-03361153GO:0008299
GeneOntologyBiologicalProcessestablishment or maintenance of cytoskeleton polarity

CKAP5 KIF2C

1.08e-0391152GO:0030952
GeneOntologyBiologicalProcesssteroid biosynthetic process

MBTPS1 CYP11A1 AKR1C1 AKR1C2 AKR1C3 PRKG1

1.13e-032091156GO:0006694
GeneOntologyBiologicalProcessmitotic sister chromatid segregation

KAT5 NCAPG2 BUB1 PCID2 LCMT1 KIF2C

1.22e-032121156GO:0000070
GeneOntologyBiologicalProcessregulation of protein localization to synapse

IQSEC2 MAGI2 KIF2C

1.24e-03381153GO:1902473
GeneOntologyBiologicalProcessretinoic acid receptor signaling pathway

AKR1C1 AKR1C2 AKR1C3

1.24e-03381153GO:0048384
GeneOntologyBiologicalProcessregulation of receptor localization to synapse

IQSEC2 MAGI2 KIF2C

1.33e-03391153GO:1902683
GeneOntologyBiologicalProcessretinoic acid metabolic process

AKR1C1 AKR1C2 AKR1C3

1.44e-03401153GO:0042573
GeneOntologyBiologicalProcesschromosome separation

NCAPG2 BUB1 PCID2 LCMT1

1.49e-03881154GO:0051304
GeneOntologyCellularComponentcondensed chromosome

MRE11 LRWD1 KAT5 ERCC6L CKAP5 NCAPG2 FANCD2 BUB1 KIF2C

4.44e-053071139GO:0000793
GeneOntologyCellularComponentgamma DNA polymerase complex

POLG2 DNA2

8.66e-0531132GO:0005760
GeneOntologyCellularComponentchromosomal region

MRE11 LRWD1 SETX KAT5 ERCC6L KDM4C CKAP5 BUB1 DNA2 KIF2C

9.67e-0542111310GO:0098687
GeneOntologyCellularComponentkinetochore

LRWD1 KAT5 ERCC6L CKAP5 BUB1 KIF2C

4.56e-041811136GO:0000776
GeneOntologyCellularComponentnuclear chromosome

MRE11 LRWD1 SETX KAT5 SMARCAL1 NCAPG2 ZMIZ2

4.66e-042541137GO:0000228
GeneOntologyCellularComponentcondensed chromosome, centromeric region

LRWD1 KAT5 ERCC6L CKAP5 BUB1 KIF2C

6.39e-041931136GO:0000779
GeneOntologyCellularComponentchromosome, centromeric region

LRWD1 KAT5 ERCC6L KDM4C CKAP5 BUB1 KIF2C

7.61e-042761137GO:0000775
GeneOntologyCellularComponentreplication fork

MRE11 SMARCAL1 RFC1 ZMIZ2

8.09e-04771134GO:0005657
MousePhenoparturition failure

AKR1C1 AKR1C2 AKR1C3

3.52e-0510953MP:0012010
MousePhenohypermyelination

AKR1C1 AKR1C2 AKR1C3

4.82e-0511953MP:0010050
MousePhenoincreased oligodendrocyte number

AKR1C1 AKR1C2 AKR1C3

8.28e-0513953MP:0010160
MousePhenoincreased circulating progesterone level

AKR1C1 AKR1C2 AKR1C3

1.30e-0415953MP:0005186
MousePhenolong stride length

AKR1C1 AKR1C2 AKR1C3

1.30e-0415953MP:0010540
MousePhenolong gestation period

AKR1C1 AKR1C2 AKR1C3

1.30e-0415953MP:0002293
DomainARM-type_fold

KPNA4 TNPO1 HIP1 CKAP5 NCAPG2 MAP3K1 ITPR1 XPO6 ZER1 TAF6 TARBP1

7.93e-0633911511IPR016024
DomainALDOKETO_REDUCTASE_1

AKR1C1 AKR1C2 AKR1C3

2.64e-05101153PS00798
DomainAldo/ket_reductase_CS

AKR1C1 AKR1C2 AKR1C3

2.64e-05101153IPR018170
DomainAldo/keto_reductase

AKR1C1 AKR1C2 AKR1C3

2.64e-05101153IPR020471
DomainALDOKETO_REDUCTASE_2

AKR1C1 AKR1C2 AKR1C3

2.64e-05101153PS00062
DomainALDOKETO_REDUCTASE_3

AKR1C1 AKR1C2 AKR1C3

2.64e-05101153PS00063
DomainARM-like

KPNA4 TNPO1 SETX CKAP5 NCAPG2 XPO6 ZER1 TAF6 TARBP1

4.46e-052701159IPR011989
Domain-

AKR1C1 AKR1C2 AKR1C3

1.20e-041611533.20.20.100
DomainNADP_OxRdtase_dom

AKR1C1 AKR1C2 AKR1C3

1.45e-04171153IPR023210
DomainAldo_ket_red

AKR1C1 AKR1C2 AKR1C3

1.45e-04171153PF00248
DomainAldo/ket_red/Kv-b

AKR1C1 AKR1C2 AKR1C3

1.45e-04171153IPR001395
Domain-

KPNA4 TNPO1 CKAP5 NCAPG2 XPO6 ZER1 TAF6

4.51e-0422211571.25.10.10
DomainCNMP_BINDING_1

KCNH3 PRKG1 KCNH5

9.90e-04321153PS00888
DomainCNMP_BINDING_2

KCNH3 PRKG1 KCNH5

9.90e-04321153PS00889
DomaincNMP

KCNH3 PRKG1 KCNH5

1.18e-03341153SM00100
DomaincNMP_binding

KCNH3 PRKG1 KCNH5

1.18e-03341153PF00027
DomaincNMP-bd_dom

KCNH3 PRKG1 KCNH5

1.29e-03351153IPR000595
DomainCNMP_BINDING_3

KCNH3 PRKG1 KCNH5

1.29e-03351153PS50042
DomainMIR

POMT2 ITPR1

1.64e-03101152PS50919
DomainMIR

POMT2 ITPR1

1.64e-03101152PF02815
DomainMIR

POMT2 ITPR1

1.64e-03101152SM00472
DomainPAS_9

KCNH3 KCNH5

1.64e-03101152PF13426
DomainMIR_motif

POMT2 ITPR1

1.64e-03101152IPR016093
DomaincNMP-bd-like

KCNH3 PRKG1 KCNH5

1.64e-03381153IPR018490
Domain-

LNX2 ANKFY1 KDM4C ZNF423 RNF213 MAP3K1 ZMIZ2 KDM2A LNX1

1.84e-0344911593.30.40.10
DomainZnf_RING/FYVE/PHD

LNX2 ANKFY1 KDM4C ZNF423 RNF213 MAP3K1 ZMIZ2 KDM2A LNX1

2.14e-034591159IPR013083
DomainHEAT

TNPO1 CKAP5 NCAPG2

3.21e-03481153PF02985
Domain-

KCNH3 PRKG1 KCNH5

3.21e-034811532.60.120.10
DomainK_chnl_volt-dep_EAG/ELK/ERG

KCNH3 KCNH5

3.26e-03141152IPR003938
DomainIMPORTIN_B_NT

TNPO1 XPO6

3.26e-03141152PS50166
Domain-

LRWD1 PRAMEF17 LRRC8D NLRP14 ZER1 KDM2A NLRP5

3.74e-0332111573.80.10.10
DomainIBN_N

TNPO1 XPO6

3.74e-03151152PF03810
DomainRmlC-like_jellyroll

KCNH3 PRKG1 KCNH5

3.82e-03511153IPR014710
DomainL_dom-like

LRWD1 PRAMEF17 LRRC8D NLRP14 ZER1 KDM2A NLRP5

4.20e-033281157IPR032675
DomainIBN_N

TNPO1 XPO6

4.26e-03161152SM00913
DomainImportin-beta_N

TNPO1 XPO6

4.81e-03171152IPR001494
DomainHEAT

TNPO1 CKAP5 NCAPG2

5.49e-03581153IPR000357
DomainP-loop_NTPase

SETX ERCC6L SMARCAL1 PSMC1 RNF213 RFC1 MAGI2 NLRP14 NWD2 DNA2 KIF2C NLRP5

6.02e-0384811512IPR027417
PathwayWP_BENZOAPYRENE_METABOLISM

AKR1C1 AKR1C2 AKR1C3

1.50e-059813M39344
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY

AKR1C1 AKR1C2 AKR1C3

1.50e-059813M47817
PathwayKEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM

AKR1C1 AKR1C2 AKR1C3

2.92e-0511813M47812
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

5.01e-0513813M17842
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

5.01e-0513813MM14747
PathwayWP_GLUCOCORTICOID_BIOSYNTHESIS

AKR1C1 AKR1C2 AKR1C3

6.36e-0514813M46449
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

6.36e-0514813M27074
PathwayWP_MINERALOCORTICOID_BIOSYNTHESIS

AKR1C1 AKR1C2 AKR1C3

6.36e-0514813M46453
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

6.36e-0514813MM14748
PathwayREACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX

AKR1C1 AKR1C2 AKR1C3

7.91e-0515813MM14870
PathwayREACTOME_METABOLISM_OF_STEROIDS

MBTPS1 CYP11A1 AKR1C1 AKR1C2 SLCO1A2 AKR1C3

8.49e-05126816MM15553
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C1 AKR1C2 SLCO1A2 AKR1C3

1.15e-0444814M499
PathwayWP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION

CYP11A1 AKR1C1 AKR1C2 AKR1C3

1.26e-0445814M39355
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C1 AKR1C2 SLCO1A2 AKR1C3

1.26e-0445814MM14751
PathwayREACTOME_CELL_CYCLE_CHECKPOINTS

MRE11 KAT5 ERCC6L CKAP5 PSMC1 BUB1 DNA2 KIF2C

1.61e-04271818MM15388
PathwayREACTOME_METABOLISM_OF_STEROIDS

MBTPS1 CYP11A1 AKR1C1 AKR1C2 SLCO1A2 AKR1C3

2.55e-04154816M27832
PathwayREACTOME_CELL_CYCLE_CHECKPOINTS

MRE11 KAT5 ERCC6L CKAP5 PSMC1 BUB1 DNA2 KIF2C

2.61e-04291818M16647
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

CYP11A1 AKR1C1 AKR1C2 AKR1C3

2.76e-0455814M14933
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

2.98e-0423813M1926
PathwayREACTOME_PREDNISONE_ADME

AKR1C1 AKR1C2 AKR1C3

2.98e-0423813MM16639
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

2.98e-0423813MM14741
PathwayKEGG_MEDICUS_REFERENCE_RORA_MEDIATED_TRANSCRIPTION

KAT5 ITPR1

3.22e-045812M49011
PathwayREACTOME_HDR_THROUGH_HOMOLOGOUS_RECOMBINATION_HRR

MRE11 KAT5 RFC1 DNA2

3.62e-0459814MM15283
PathwayREACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE

MRE11 KAT5 DNA2

4.32e-0426813MM15297
PathwayREACTOME_SENSING_OF_DNA_DOUBLE_STRAND_BREAKS

MRE11 KAT5

4.82e-046812M27585
PathwayREACTOME_SENSING_OF_DNA_DOUBLE_STRAND_BREAKS

MRE11 KAT5

4.82e-046812MM15295
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ATXN1_TO_RORA_MEDIATED_TRANSCRIPTION

KAT5 ITPR1

4.82e-046812M47665
PathwayREACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES_THROUGH_SYNTHESIS_DEPENDENT_STRAND_ANNEALING_SDSA

MRE11 KAT5 DNA2

4.84e-0427813M27586
PathwayREACTOME_RA_BIOSYNTHESIS_PATHWAY

AKR1C1 AKR1C2 AKR1C3

5.40e-0428813MM15188
PathwayREACTOME_CELL_CYCLE

TNPO1 MRE11 KAT5 ERCC6L CKAP5 PSMC1 RFC1 NCAPG2 BUB1 DNA2 LCMT1 KIF2C

5.74e-046948112M543
PathwayREACTOME_CELL_CYCLE

MRE11 KAT5 ERCC6L CKAP5 PSMC1 RFC1 NCAPG2 BUB1 DNA2 LCMT1 KIF2C

6.38e-046038111MM14635
PathwayREACTOME_HDR_THROUGH_HOMOLOGOUS_RECOMBINATION_HRR

MRE11 KAT5 RFC1 DNA2

6.95e-0470814M27570
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C1 AKR1C2 AKR1C3

8.81e-0433813M5967
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C1 AKR1C2 AKR1C3

8.81e-0433813MM14737
PathwayWP_JOUBERT_SYNDROME

MRE11 KAT5 ZNF423 INVS

9.48e-0476814M39835
PathwayPID_ATM_PATHWAY

MRE11 KAT5 FANCD2

9.62e-0434813M84
PathwayREACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES

MRE11 KAT5 DNA2

1.05e-0335813MM15293
PathwayREACTOME_HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA

MRE11 KAT5 DNA2

1.14e-0336813MM15281
PathwayWP_STEROID_HORMONE_PRECURSOR_BIOSYNTHESIS

CYP11A1 AKR1C1

1.14e-039812M46465
PathwayREACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES

MRE11 KAT5 DNA2

1.23e-0337813M27583
PathwayREACTOME_HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA

MRE11 KAT5 DNA2

1.23e-0337813M27568
PathwayREACTOME_CELL_CYCLE_MITOTIC

TNPO1 ERCC6L CKAP5 PSMC1 RFC1 NCAPG2 BUB1 DNA2 LCMT1 KIF2C

1.36e-035618110M5336
PathwayREACTOME_CGMP_EFFECTS

ITPR1 PRKG1

1.42e-0310812MM15054
PathwayWP_ALTERNATIVE_PATHWAY_OF_FETAL_ANDROGEN_SYNTHESIS

CYP11A1 AKR1C2

1.73e-0311812M39749
PathwayREACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE

MRE11 KAT5 DNA2

1.91e-0343813M27588
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION

MRE11 KAT5 TAF6 DNA2

1.93e-0392814MM15338
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

AKR1C1 AKR1C2 NMT2 AKR1C3

1.93e-0392814MM14881
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION

MRE11 KAT5 TAF6 DNA2

1.93e-0392814M27636
PathwayREACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION

PSMC1 RNF213 ASB15 THOP1 UBA6 LNX1 HERC5

1.94e-03308817M1070
Pubmed

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity.

CYP11A1 AKR1C1 AKR1C2 AKR1C3

8.14e-098116433584538
Pubmed

Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival.

AKR1C1 AKR1C2 AKR1C3

3.62e-083116319320734
Pubmed

Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis.

AKR1C1 AKR1C2 AKR1C3

3.62e-083116331780644
Pubmed

Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.

AKR1C1 AKR1C2 AKR1C3

3.62e-083116321232532
Pubmed

Altered expression of 3 alpha-hydroxysteroid dehydrogenases in human glaucomatous optic nerve head astrocytes.

AKR1C1 AKR1C2 AKR1C3

3.62e-083116313678667
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

KPNA4 KDM4C ZNF423 IQSEC2 CKAP5 PSMC1 CLIC6 BHLHE40 WDR47 MAGI2 THOP1 NMT2 AKR1C3 TAF6 LNX1 ST18 TARBP1 MITD1 DOP1B

5.16e-0812851161935914814
Pubmed

Endogenous biotin as a marker of adrenocortical cells with steroidogenic potential.

CYP11A1 AKR1C1 AKR1C2 AKR1C3

5.70e-0812116421256921
Pubmed

A Novel Population of Inner Cortical Cells in the Adrenal Gland That Displays Sexually Dimorphic Expression of Thyroid Hormone Receptor-β1.

CYP11A1 AKR1C1 AKR1C2 AKR1C3

5.70e-0812116425774556
Pubmed

Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung.

CYP11A1 AKR1C1 AKR1C2 AKR1C3

8.21e-0813116424580729
Pubmed

Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages.

CYP11A1 AKR1C1 AKR1C2 AKR1C3

1.15e-0714116419955443
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MBTPS1 ANKFY1 ZNF423 CKAP5 URB2 WDR47 MAGI2 ZFR2 ST18 BAIAP3 DOP1B

1.29e-074071161112693553
Pubmed

Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116320124700
Pubmed

Structure and activity of the murine type 5 17beta-hydroxysteroid dehydrogenase gene(1).

AKR1C1 AKR1C2 AKR1C3

1.44e-074116310500239
Pubmed

Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116316508162
Pubmed

AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116319487289
Pubmed

Cloning and chromosomal localization of mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116314967952
Pubmed

Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: identification of a new syntenic relationship.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116310393440
Pubmed

Localization of 20alpha-hydroxysteroid dehydrogenase mRNA in mouse brain by in situ hybridization.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116315193432
Pubmed

Mouse Akr1cl gene product is a prostaglandin D2 11-ketoreductase with strict substrate specificity.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116331479646
Pubmed

Characterization and functional analysis of the 5'-flanking region of the mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116315222881
Pubmed

Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116316191478
Pubmed

Characterization of two isoforms of mouse 3(17)alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase family.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116315577209
Pubmed

Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116310702227
Pubmed

Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116317034817
Pubmed

Several distinct enzymes catalyze 20alpha-hydroxysteroid dehydrogenase activity in mouse liver and kidney.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116317629694
Pubmed

RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116329764944
Pubmed

Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116310526179
Pubmed

Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116317888864
Pubmed

Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116317442338
Pubmed

Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116328329705
Pubmed

Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17alpha-HSD) and its involvement in the biosynthesis of epitestosterone.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116316018803
Pubmed

Reproductive phenotypes in mice with targeted disruption of the 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116317272929
Pubmed

Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116319237748
Pubmed

Involvement of 20alpha-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116318667791
Pubmed

Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116328259989
Pubmed

Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116321521174
Pubmed

Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.

AKR1C1 AKR1C2 AKR1C3

1.44e-07411638274401
Pubmed

Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116316511129
Pubmed

Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116310803568
Pubmed

AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway.

AKR1C1 AKR1C2 AKR1C3

1.44e-074116334590152
Pubmed

Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2) and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chain reaction and fluorescence in situ hybridization.

AKR1C1 AKR1C2 AKR1C3

1.44e-07411637789999
Pubmed

Molecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase family.

AKR1C1 AKR1C2 AKR1C3

3.60e-07511637737980
Pubmed

Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.

AKR1C1 AKR1C2 AKR1C3

3.60e-075116321851338
Pubmed

Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice.

AKR1C1 AKR1C2 AKR1C3

3.60e-075116317872381
Pubmed

Mouse 3alpha-hydroxysteroid dehydrogenase mRNA: a marker of lung maturity.

AKR1C1 AKR1C2 AKR1C3

3.60e-075116317064890
Pubmed

Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes.

AKR1C1 AKR1C2 AKR1C3

3.60e-075116310672042
Pubmed

Pregnane X receptor (PXR) deficiency promotes hepatocarcinogenesis via induction of Akr1c18 expression and prostaglandin F2α (PGF2α) levels.

AKR1C1 AKR1C2 AKR1C3

3.60e-075116338788959
Pubmed

Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma.

AKR1C1 AKR1C2 AKR1C3

3.60e-075116315212687
Pubmed

Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.

AKR1C1 AKR1C2 AKR1C3

3.60e-075116316984997
Pubmed

Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.

AKR1C1 AKR1C2 AKR1C3

3.60e-075116318003893
Pubmed

WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland.

CYP11A1 AKR1C1 AKR1C2 AKR1C3

5.46e-0720116424135228
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

TNPO1 MRE11 LRWD1 SETX ERCC6L CKAP5 PSMC1 SRP72 FANCD2 XPO6 BUB1 KIF2C

6.11e-075821161220467437
Pubmed

The Gαq/11-provoked induction of Akr1c18 in murine luteal cells is mediated by phospholipase C.

AKR1C1 AKR1C2 AKR1C3

7.18e-076116329107092
Pubmed

Expression analysis of the aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues.

AKR1C1 AKR1C2 AKR1C3

7.18e-076116319273550
Pubmed

Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase.

AKR1C1 AKR1C2 AKR1C3

7.18e-076116315860270
Pubmed

Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase.

AKR1C1 AKR1C2 AKR1C3

7.18e-076116315471942
Pubmed

MEF2 and NR2F2 cooperate to regulate Akr1c14 gene expression in mouse MA-10 Leydig cells.

AKR1C1 AKR1C2 AKR1C3

7.18e-076116326748576
Pubmed

Adrenal 20alpha-hydroxysteroid dehydrogenase in the mouse catabolizes progesterone and 11-deoxycorticosterone and is restricted to the X-zone.

AKR1C1 AKR1C2 AKR1C3

7.18e-076116317122075
Pubmed

Decidual prolactin silences the expression of genes detrimental to pregnancy.

AKR1C1 AKR1C2 AKR1C3

7.18e-076116317255200
Pubmed

The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer Cells.

AKR1C1 AKR1C2 AKR1C3

1.25e-067116326160177
Pubmed

Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets.

AKR1C1 AKR1C2 AKR1C3

1.25e-067116334843575
Pubmed

MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.

AKR1C1 AKR1C2 AKR1C3

1.25e-067116322529366
Pubmed

A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: Phenotype and impact on adrenocortical function.

AKR1C1 AKR1C2 AKR1C3

1.25e-067116333127481
Pubmed

Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk.

AKR1C1 AKR1C2 AKR1C3

1.25e-067116319846565
Pubmed

A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13.

AKR1C1 AKR1C2 AKR1C3

1.25e-067116312562828
Pubmed

17Beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: a novel role for androgen during the surge of surfactant.

AKR1C1 AKR1C2 AKR1C3

1.25e-067116316337335
Pubmed

Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.

AKR1C1 AKR1C2 P2RX1 AKR1C3

1.66e-0626116423892084
Pubmed

Identification of differentially expressed genes in mouse spermatogenesis.

AKR1C1 AKR1C2 UBA6 AKR1C3

1.94e-0627116414581517
Pubmed

Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice.

CYP11A1 AKR1C1 AKR1C2 AKR1C3

1.94e-0627116423471215
Pubmed

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

AKR1C1 AKR1C2 AKR1C3

2.00e-068116320837989
Pubmed

Cloning of mouse 17beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues.

AKR1C1 AKR1C2 AKR1C3

2.00e-06811639224647
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

KPNA4 TNPO1 MRE11 MBTPS1 SZT2 SMARCAL1 MPDU1 TTC4 NCAPG2 FANCD2 SNX14 WDR20 KDM2A TMED10 TAF6 CRAMP1 LCMT1

2.01e-0613271161732694731
Pubmed

MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation.

CYP11A1 AKR1C1 AKR1C2 AKR1C3

2.26e-0628116429879378
Pubmed

Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models.

AKR1C1 AKR1C2 AKR1C3

2.99e-069116333348080
Pubmed

Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility, and metabolic homeostasis in female mice.

CYP11A1 AKR1C1 AKR1C2 AKR1C3

3.93e-0632116434288113
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TRERF1 MRE11 LRWD1 SETX INPP5D CKAP5 PSMC1 SRP72 RFC1 NCAPG2 ZMIZ2 TMED10 TAF6 MITD1 KIF2C

4.16e-0611031161534189442
Pubmed

Lack of placental neurosteroid alters cortical development and female somatosensory function.

AKR1C1 AKR1C2 AKR1C3

4.26e-0610116336313771
Pubmed

Characterization of prostate cancer bone metastases according to expression levels of steroidogenic enzymes and androgen receptor splice variants.

CYP11A1 AKR1C2 AKR1C3

4.26e-0610116324244276
Pubmed

A balance between elongation and trimming regulates telomere stability in stem cells.

MRE11 SMARCAL1 DNA2

4.26e-0610116327918544
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CFAP47 MRE11 SETX TTC21A IQSEC2 CKAP5 PSMC1 RNF213 NFASC ZFR2 IGSF9B DOP1B

6.82e-067361161229676528
Pubmed

Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1.

AKR1C1 AKR1C2 AKR1C3

7.78e-0612116328893949
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SLC37A1 MBTPS1 TTC21A RNF213 NFASC ST3GAL1 LRRC8D ZNF248 PTPDC1 THOP1 NACC2 UBA6 KDM2A IGSF9B BAIAP3 CRAMP1 INVS

9.21e-0614891161728611215
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

KPNA4 MRE11 HIP1 LRWD1 SETX KAT5 CKAP5 PSMC1 SRP72 URB2 MYLK2 NMT2 WDR20 TMED10 TAF6 PCID2 KIF2C

9.87e-0614971161731527615
Pubmed

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.

AKR1C1 AKR1C2 AKR1C3

1.01e-0513116311682476
Pubmed

Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.

AKR1C1 AKR1C2 AKR1C3

1.01e-0513116317062636
Pubmed

A link between lung androgen metabolism and the emergence of mature epithelial type II cells.

AKR1C1 AKR1C2 AKR1C3

1.01e-0513116315117747
Pubmed

Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling.

MRE11 ZNF423 INVS

1.01e-0513116322863007
Pubmed

Expression of TIP60 (tat-interactive protein) and MRE11 (meiotic recombination 11 homolog) predict treatment-specific outcome of localised invasive bladder cancer.

MRE11 KAT5

1.10e-052116223046361
Pubmed

Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells.

AKR1C1 AKR1C2

1.10e-05211628573067
Pubmed

Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution.

AKR1C1 AKR1C2

1.10e-052116211514561
Pubmed

Selective loss of AKR1C1 and AKR1C2 in breast cancer and their potential effect on progesterone signaling.

AKR1C1 AKR1C2

1.10e-052116215492289
Pubmed

The ligands of Numb proteins X1 and X2 are specific markers for chronic Q fever.

LNX2 LNX1

1.10e-052116222066909
Pubmed

Local androgen inactivation in abdominal visceral adipose tissue.

AKR1C2 AKR1C3

1.10e-052116214671194
Pubmed

FANCD2 promotes mitotic rescue from transcription-mediated replication stress in SETX-deficient cancer cells.

SETX FANCD2

1.10e-052116236543851
Pubmed

Hypopigmentation and maternal-zygotic embryonic lethality caused by a hypomorphic mbtps1 mutation in mice.

MBTPS1 TYR

1.10e-052116222540041
Pubmed

AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer.

AKR1C1 AKR1C3

1.10e-052116216338060
Pubmed

Clinical and molecular characterization of ataxia with oculomotor apraxia patients in Saudi Arabia.

MRE11 SETX

1.10e-052116221324166
Pubmed

Pathophysiological roles of aldo-keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers.

AKR1C1 AKR1C3

1.10e-052116223165153
Pubmed

AKR1C2 and AKR1C3 expression in adipose tissue: Association with body fat distribution and regulatory variants.

AKR1C2 AKR1C3

1.10e-052116233675863
Pubmed

Transcriptomic Profiling Reveals AKR1C1 and AKR1C3 Mediate Cisplatin Resistance in Signet Ring Cell Gastric Carcinoma via Autophagic Cell Death.

AKR1C1 AKR1C3

1.10e-052116234830394
InteractionHDAC1 interactions

KPNA4 TRERF1 MBTPS1 ANKFY1 KAT5 KDM4C PLEKHG7 ZNF423 CKAP5 PSMC1 RFC1 TTC4 BHLHE40 STAT2 FANCD2 NACC2 ZMIZ2 BUB1 CARNMT1 PRKG1 TAF6 MXD1 HERC5 BAHCC1

1.08e-08110811424int:HDAC1
InteractionSIGLECL1 interactions

TNPO1 EXOC6 SETX RNF213 SNX14 XPO6 SIGLECL1

3.63e-061131147int:SIGLECL1
InteractionGYPA interactions

TNPO1 EXOC6 SETX CKAP5 URB2 STAT2 XPO6 TARBP1

6.64e-061741148int:GYPA
InteractionAKR1C4 interactions

AKR1C1 AKR1C2 AKR1C3

9.67e-0681143int:AKR1C4
InteractionNPTN interactions

TNPO1 EXOC6 SETX RNF213 FANCD2 XPO6 LNX1 TARBP1 DOP1B

2.91e-052781149int:NPTN
InteractionTSN interactions

MRE11 TTC4 UBA6 TAF6 LNX1 BAHCC1

3.81e-051101146int:TSN
Cytoband10p15-p14

AKR1C1 AKR1C2 AKR1C3

3.13e-076116310p15-p14
Cytoband3p26

BHLHE40 FANCD2

1.75e-04811623p26
Cytoband1p34.2

EXO5 SZT2 ZMYM6

4.16e-045711631p34.2
Cytoband3q25.33

KPNA4 IL12A

5.65e-041411623q25.33
GeneFamilyAldo-keto reductases

AKR1C1 AKR1C2 AKR1C3

4.38e-0515853399
GeneFamilyUPF1 like RNA helicases

SETX DNA2

1.17e-03118521169
CoexpressionIRITANI_MAD1_TARGETS_UP

AKR1C1 AKR1C2 AKR1C3 MXD1

8.01e-07171154MM826
CoexpressionGSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN

RFC1 AKR1C2 THOP1 XPO6 BUB1 HERPUD1 INVS KIF2C

2.94e-062001158M4538
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_UP

AKR1C1 AKR1C2 SLCO1A2 BUB1 AKR1C3 P2RY14 KIF2C

4.57e-061501157MM936
CoexpressionGSE34156_UNTREATED_VS_6H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN

MBTPS1 KDM4C RNF213 STAT2 ITPR1 P2RY14 HERC5

6.98e-061601157M8664
CoexpressionGSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_DN

HIP1 RNF213 LRRC8D BHLHE40 STAT2 HERPUD1 MXD1

2.13e-051901157M384
CoexpressionGSE20727_DNFB_ALLERGEN_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN

CYP11A1 CKAP5 BHLHE40 CARNMT1 DNA2 BAIAP3 KIF2C

2.87e-051991157M9256
CoexpressionGSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDC_DN

SLC37A1 HIP1 RFC1 ITPR1 P2RY14 TAF6 PCID2

2.96e-052001157M3777
CoexpressionGSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_UP

HIP1 EXO5 NCAPG2 BUB1 DNA2 BAIAP3 MITD1

2.96e-052001157M4327
CoexpressionSHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6

POMT2 ERCC6L NCAPG2 CHRNA5 ZNF248 THOP1 BUB1 UBA6 DNA2 KIF2C

3.50e-0545811510M8520
CoexpressionFAN_EMBRYONIC_CTX_MICROGLIA_1

CKAP5 NCAPG2 FANCD2 BUB1 HERC5 KIF2C

6.42e-051551156M39041
CoexpressionKONG_E2F3_TARGETS

ERCC6L NCAPG2 BUB1 DNA2 KIF2C

6.96e-05971155MM1105
CoexpressionKONG_E2F3_TARGETS

ERCC6L NCAPG2 BUB1 DNA2 KIF2C

8.05e-051001155M1157
CoexpressionYAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6

F3 AKR1C1 AKR1C2 MAP3K1 AKR1C3

8.84e-051021155MM872
CoexpressionGAO_LARGE_INTESTINE_ADULT_CH_MKI67HIGH_CELLS

ERCC6L FANCD2 BUB1 DNA2 KIF2C

1.11e-041071155M39165
CoexpressionFERRARI_RESPONSE_TO_FENRETINIDE_UP

ST3GAL1 BHLHE40 HERPUD1

1.19e-04221153M14827
CoexpressionGSE37532_WT_VS_PPARG_KO_LN_TREG_UP

POMT2 LNX2 LRRC8D P2RY14 TAF6 MXD1

1.29e-041761156M8952
CoexpressionLIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK

AKR1C1 AKR1C2 AKR1C3

1.56e-04241153MM766
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_C_DN

AKR1C1 AKR1C2 AKR1C3

1.76e-04251153MM480
CoexpressionGSE15659_TREG_VS_TCONV_DN

ANKFY1 CLIC6 BHLHE40 NWD2 P2RY14 IGSF9B

1.85e-041881156M3535
CoexpressionGSE21927_BALBC_VS_C57BL6_MONOCYTE_SPLEEN_UP

MRE11 HIP1 LNX2 RUBCNL P2RY14 DNA2

1.90e-041891156M7569
CoexpressionGSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_UP

POMT2 SMARCAL1 ZNF248 AKR1C3 PCID2 DOP1B

2.26e-041951156M3184
CoexpressionGSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP

SZT2 RFC1 TYR P2RX1 P2RY14 ST18

2.45e-041981156M4432
CoexpressionGSE360_CTRL_VS_L_MAJOR_DC_UP

IL12A KAT5 INPP5D INVS DOP1B KIF2C

2.52e-041991156M5145
CoexpressionGSE3982_DC_VS_TH1_DN

ZNF142 MPDU1 RFC1 BUB1 MXD1 KIF2C

2.52e-041991156M5482
CoexpressionGSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN

MBTPS1 KDM4C ST3GAL1 FANCD2 P2RX1 P2RY14

2.52e-041991156M9236
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

LETM2 RNF213 NFASC ZMIZ2 P2RY14 CARNMT1

2.52e-041991156M9184
CoexpressionGSE41867_NAIVE_VS_EFFECTOR_CD8_TCELL_DN

KPNA4 URB2 BHLHE40 ZMIZ2 CARNMT1 MITD1

2.58e-042001156M9475
CoexpressionGSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_UP

RFC1 LRRC8D BHLHE40 NACC2 TAF6 HERC5

2.58e-042001156M9591
CoexpressionGSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_DN

MBTPS1 IQSEC2 THOP1 NACC2 XPO6 TARBP1

2.58e-042001156M5262
CoexpressionGSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDC_UP

ERCC6L SMARCAL1 STAT2 SLCO1A2 MITD1 DOP1B

2.58e-042001156M3778
CoexpressionGSE17721_0.5H_VS_4H_POLYIC_BMDC_UP

HIP1 RFC1 MAGI2 P2RX1 TAF6 LCMT1

2.58e-042001156M4089
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#1_top-relative-expression-ranked_500

ERCC6L NCAPG2 FANCD2 NMT2 BUB1 KIF2C

2.30e-051051156gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k1_500
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

MBTPS1 ANKFY1 RNF213 ZDHHC23 DNA2 INVS DOP1B

7.02e-0719111679454f642c3621370fa23640b631301346b300950
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ERCC6L CKAP5 NCAPG2 FANCD2 BUB1 DNA2 KIF2C

7.27e-07192116727723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCellcycling_basal_cell|World / shred by cell class for nasal brushing

ERCC6L NCAPG2 CHRNA5 FANCD2 BUB1 DNA2 KIF2C

8.35e-071961167aa7bac70a2fe4a3cb28d89fa1a87c68c2ead1349
ToppCellSepsis-URO-Lymphocyte-T/NK-T/NK_proliferative|URO / Disease, condition lineage and cell class

ERCC6L NCAPG2 BUB1 IGSF9B DNA2 INVS KIF2C

9.56e-072001167f277db6cc288a52a5426120c1067608700ee8ccc
ToppCellLPS-antiTNF-Unknown-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERCC6L NFASC TYR BUB1 P2RY14 KIF2C

1.19e-061301166615c233c7c2600c1c2bc5cf5b1c501fc474564ef
ToppCellE12.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

POMT2 SLC37A1 CFAP47 IL12A PSMC1 LRRC8D

2.07e-061431166cc396b81a5e47d78c2d1cb49d682391376b63476
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERCC6L CKAP5 NCAPG2 FANCD2 BUB1 KIF2C

4.40e-0616311665285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERCC6L CKAP5 NCAPG2 FANCD2 BUB1 KIF2C

7.77e-061801166334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKAP5 NCAPG2 FANCD2 BUB1 P2RY14 KIF2C

7.77e-06180116643fd5c498a87bb078d101298b472656f3294686a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CKAP5 NCAPG2 FANCD2 BUB1 P2RY14 KIF2C

8.54e-061831166e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCell3'_v3-blood-Lymphocytic_B|blood / Manually curated celltypes from each tissue

PLEKHG7 RUBCNL ITPR1 ZDHHC23 P2RY14 BAIAP3

9.37e-0618611665624b1fc7eab9f505588fcc86a24d14f8bcbfef7
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERCC6L CKAP5 NCAPG2 FANCD2 BUB1 KIF2C

1.03e-0518911661e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CKAP5 NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.06e-051901166d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellDividing_Macrophages-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ERCC6L NCAPG2 CHRNA5 BUB1 HERC5 KIF2C

1.09e-0519111663e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCellB_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PLEKHG7 INPP5D RUBCNL MAP3K1 P2RX1 HERPUD1

1.09e-05191116672e3191990973440e4f91427208df360f73e4f41
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ERCC6L CKAP5 NCAPG2 BUB1 DNA2 KIF2C

1.12e-0519211660a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 NFASC MYLK2 P2RX1 IGSF9B PRKG1

1.12e-051921166bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 NFASC MYLK2 P2RX1 IGSF9B PRKG1

1.12e-051921166b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CKAP5 NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.16e-0519311664b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ERCC6L NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.19e-051941166f9070035553bc68106a9e0bdf4b507715a138aba
ToppCellcontrol-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RNF213 STAT2 XPO6 P2RY14 MXD1 HERC5

1.19e-051941166267e213e8efe53aadfe553a2ca010a0e3b4b8939
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

CKAP5 NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.23e-051951166764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERCC6L NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.26e-0519611661964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERCC6L NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.26e-05196116673f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ERCC6L NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.30e-05197116684ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

RNF213 BHLHE40 STAT2 KDM2A MXD1 HERC5

1.34e-05198116661ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellmedial-2-Hematologic-Proliferating_Macrophage|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ERCC6L NCAPG2 FANCD2 BUB1 HERC5 KIF2C

1.34e-05198116664a2bcf5a9ba66a4fe08fbde33f1886c136cde8f
ToppCellmedial-Hematologic-Proliferating_Macrophage-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ERCC6L NCAPG2 FANCD2 BUB1 HERC5 KIF2C

1.34e-051981166fcc14ac3eb5088b9d6cd6af5a34dee5b81c0ece8
ToppCelldistal-Hematologic-Proliferating_Macrophage-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPG2 CHRNA5 FANCD2 BUB1 HERC5 KIF2C

1.34e-0519811662b0716e900bce54ad1825d6dcdaf4ebf31f355c4
ToppCellmedial-Hematologic-Proliferating_Macrophage|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ERCC6L NCAPG2 FANCD2 BUB1 HERC5 KIF2C

1.34e-051981166da6963184c32761c896a9b91a5321ad84b583736
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERCC6L CKAP5 NCAPG2 FANCD2 BUB1 KIF2C

1.38e-0519911664af38f5e9d2229d64f7ecdf9c00b4d67e5f86a51
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ERCC6L CKAP5 NCAPG2 FANCD2 BUB1 KIF2C

1.38e-051991166be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellControl-Control-Lymphocyte-T/NK-T/NK_proliferative|Control / Disease, condition lineage and cell class

ERCC6L NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.41e-0520011666cf63dd57f6bc0c42e7182322dd24ff9afbe9186
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

TRERF1 CKAP5 FANCD2 P2RX1 BUB1 POLG2

1.41e-052001166118321ac443feb42aee171baccfc4610f00a8822
ToppCellNS-moderate-d_07-13-Lymphoid-NKT-proliferating|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERCC6L NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.41e-05200116687e293c0882e2754756a2210a6c04723dc89f81b
ToppCellBiopsy_Control_(H.)-Immune-Proliferating_Macrophages|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

NCAPG2 AKR1C2 BUB1 DNA2 HERC5 KIF2C

1.41e-052001166ce9fad55f779afd3d6c5a9c5a15e2d9f548b7c7e
ToppCellPSB-critical-LOC-Lymphoid-Treg|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERCC6L NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.41e-0520011663e3de496508efb2f95e5e8684f97687381e96493
ToppCellBiopsy_Other_PF-Immune-Proliferating_Macrophages|Biopsy_Other_PF / Sample group, Lineage and Cell type

ERCC6L NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.41e-05200116661473e8613f39a92002d5b631e6bd563735566e4
ToppCellBL-critical-LOC-Lymphoid-Treg|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERCC6L NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.41e-05200116604d95a9102248e98eed069840ea6d3d23a243fd5
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_activate-7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLEKHG7 RUBCNL URB2 CRAMP1 KCNH5

1.99e-051261165518a6e4919981b556ce6b451a91270dba976bc75
ToppCellLPS-antiTNF-Unknown|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERCC6L NFASC TYR BUB1 P2RY14

2.23e-051291165739b263296c28554967362060b154f7a95e1341d
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERCC6L NFASC BUB1 P2RY14 KIF2C

2.49e-05132116502491930097b75aaeedab9e8200711b0dc610944
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular|TCGA-Stomach / Sample_Type by Project: Shred V9

ERCC6L URB2 FANCD2 ZDHHC23 TARBP1

3.08e-05138116593497c0a5d5e54006653b2dedc7a7041e1a613e6
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

IL12A ZNF142 SMARCAL1 MAP3K1 ACTL10

4.59e-051501165744050a1b665c6989f37141348af3df7579a73c9
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

INPP5D RUBCNL P2RX1 P2RY14 ST18

5.36e-0515511659f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRERF1 RUBCNL P2RX1 XPO6 HERC5

5.53e-051561165f5889a6899904dfb7f596600b3a76857cf9d5378
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CCNJL BHLHE40 KCNH3 NWD2 PRKG1

5.53e-0515611652cd007b423c2395c5ce331902e7f27c805755eb3
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Pld5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IL12A HKDC1 BHLHE40 IGSF9B KCNH5

6.05e-051591165a082e770fa757c4a1d3ed13d53f83297e36faf05
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP11A1 INPP5D P2RX1 P2RY14 MXD1

6.42e-051611165d1f2e5245c7c247b684f48f9f877e149a3ee7c06
ToppCellLPS-IL1RA-Unknown-Endothelial-Monocytes-Macrophages|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IQSEC2 URB2 AKR1C2 THOP1 BAHCC1

6.81e-0516311656b11a3ada8725670d0489f404c8c2175ad3904e9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 INPP5D RUBCNL CHRNA5 P2RY14

7.42e-05166116563dc58864268b4e7779e4c45155022556fc634f9
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EXOC6 AKR1C1 MAP3K1 ZDHHC23 AKR1C3

7.42e-051661165941d6aa94ab9d36e5f6c40f446c926754e070d56
ToppCellfacs-Trachea-nan-18m-Myeloid-granulocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP11A1 INPP5D P2RX1 P2RY14 MXD1

7.42e-0516611657f8b4cf63c3e292ae421f111edaa4572717f4db1
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EXOC6 AKR1C1 MAP3K1 ZDHHC23 AKR1C3

7.42e-0516611656f5ecf3b2cf613ae0535ab3d21d93622f1497571
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

INPP5D P2RX1 P2RY14 ST18 HERPUD1

8.07e-051691165b2fdf9f842dc7c181bc951a8a6932c916ed835ef
ToppCelldroplet-Lung-nan-3m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP11A1 P2RX1 UBA6 P2RY14 MXD1

8.07e-051691165da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERCC6L CKAP5 NCAPG2 BUB1 KIF2C

8.07e-051691165e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCelldroplet-Lung-nan-3m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP11A1 P2RX1 UBA6 P2RY14 MXD1

8.07e-051691165a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

INPP5D P2RX1 P2RY14 ST18 HERPUD1

8.07e-0516911652322f03a115c662f808ebfc892192b7d38d48181
ToppCellCOVID-19-lung-MAST|lung / Disease (COVID-19 only), tissue and cell type

TRERF1 ITPR1 P2RX1 NMT2 P2RY14

8.30e-051701165e90f18e5462381b38e918442b38b1c8105291908
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCNJL AKR1C1 MAP3K1 MAGI2 SLCO1A2

8.30e-0517011655d5f208682be21ed58320f5fc083a7898f8712da
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l26|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP11A1 INPP5D P2RX1 UBA6 P2RY14

8.30e-0517011654b1c84b35b7242a297ffdb9c23a6d982acf1bed5
ToppCellhealthy_donor-Myeloid-Monocytic-Developing_Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

LETM2 NFASC P2RX1 BUB1 LNX1

8.30e-051701165cfd7f29805b7c51666b0eaf269c36c96b8765a1a
ToppCellImmune-dendritic_cell|World / Lineage, Cell type, age group and donor

TRERF1 INPP5D RUBCNL P2RY14 ST18

8.53e-0517111656a9e2e2d3e1d8cc475bf9765129bc4a32da3b8ea
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRE11 CKAP5 NCAPG2 PTPDC1 BUB1

8.77e-0517211652b6cd84c946b1e800caba452ae70145ea285fec1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 INPP5D RUBCNL P2RY14 ST18

9.01e-05173116573f858f2c45d19b9ec8d99ac02c91551790f670c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERCC6L CKAP5 FANCD2 BUB1 KIF2C

9.26e-051741165dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POMT2 TTC21A WDR47 PRKG1 BAHCC1

9.51e-051751165aa168aeb9ad71aa6c0c28a0657c9eb92a0b28183
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

INPP5D RNF213 P2RY14 TARBP1 HERC5

9.51e-05175116597616bb5c127284aa9e67bc336dfcf29e137164b
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRERF1 ERCC6L BUB1 DNA2 KIF2C

9.51e-05175116573f25bd54309aed1480ddc44bdab518b17e71f92
ToppCellCOVID-19-lung-MAST|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRERF1 ITPR1 P2RX1 NMT2 P2RY14

9.77e-051761165473c45a381ca109207d66ed1635668b391ea0e1f
ToppCellControl-B_cells-B_cells|Control / group, cell type (main and fine annotations)

INPP5D RUBCNL MAP3K1 ITPR1 P2RY14

9.77e-051761165d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

MBTPS1 RNF213 ZDHHC23 P2RY14 IGSF9B

9.77e-0517611653de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

MBTPS1 RNF213 ZDHHC23 P2RY14 IGSF9B

1.00e-04177116582fdd6185b368f54f03de389427cbe3071d21a99
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

PLEKHG7 TTC21A RNF213 STAT2 HERC5

1.00e-041771165a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellFetal_29-31_weeks-Immune-dendritic_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

INPP5D RUBCNL P2RX1 P2RY14 ST18

1.00e-041771165c5e829bc4594761666d65cace5a9c5d19c16f187
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

PLEKHG7 TTC21A RNF213 STAT2 HERC5

1.03e-041781165ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12A NFASC MAGI2 ST18 BAIAP3

1.03e-04178116530ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RUBCNL P2RX1 P2RY14 SIGLECL1 TARBP1

1.06e-041791165c9f45cfea0ceb0cdc31bcfd123aeab69aeb35c35
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPG2 CHRNA5 FANCD2 BUB1 DNA2

1.06e-04179116588d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CKAP5 NCAPG2 FANCD2 BUB1 KIF2C

1.09e-0418011655e1680088065be14447d5d5465f91f7edd071a1e
ToppCellcontrol-Lymphoid-NKT-proliferating|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ERCC6L NCAPG2 FANCD2 BUB1 KIF2C

1.09e-041801165535535a67b3f3320bad2f98b1bc98a7b0ee77840
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.09e-041801165401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HKDC1 KCNH3 RIN1 ZDHHC23 IGSF9B

1.11e-04181116558f76bb9ea1518c2b629a0256a3f6595a9278152
ToppCellP28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ERCC6L NCAPG2 FANCD2 BUB1 KIF2C

1.11e-041811165e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

TRERF1 HIP1 NFASC P2RY14 PRKG1

1.11e-0418111658dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellP28-Endothelial-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ERCC6L NCAPG2 FANCD2 BUB1 KIF2C

1.11e-0418111652be3d44619adb25d339e7a27b500a56e07e8de01
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

TRERF1 HIP1 NFASC P2RY14 PRKG1

1.14e-0418211652075efeae633550fb2eb026d0dfd741c8252482e
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|World / disease group, cell group and cell class (v2)

MYLK2 FANCD2 BUB1 DNA2 KIF2C

1.14e-0418211659adf90bb2808f234d53b89ca0ae07380478204ad
ToppCellNS-control-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERCC6L NCAPG2 FANCD2 BUB1 KIF2C

1.14e-041821165f623c47e7806181d09f126066a952162ce49a306
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

MYLK2 FANCD2 BUB1 DNA2 KIF2C

1.17e-041831165df8568751205313d149939ea2683097e3652a60b
ToppCellBac-SEP-Lymphocyte-T_NK-T_NK_proliferative|Bac-SEP / Disease, Lineage and Cell Type

ERCC6L NCAPG2 FANCD2 BUB1 KIF2C

1.20e-041841165848d05afd5a2ef61fb8a09c0f5fa2a56fd5c160b
ToppCellURO-Lymphocyte-T_NK-T_NK_proliferative|URO / Disease, Lineage and Cell Type

ERCC6L NCAPG2 BUB1 IGSF9B KIF2C

1.23e-0418511650ae9c646679c69a553eda670aef0e0495feb0286
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

NCAPG2 FANCD2 BUB1 DNA2 KIF2C

1.23e-0418511659766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CKAP5 NCAPG2 FANCD2 BUB1 KIF2C

1.23e-04185116530e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 INPP5D RUBCNL P2RY14 ST18

1.27e-041861165305f1726b8b5add32f1c29c74991ff34f42e0da7
ToppCellDividing_Macrophages-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CKAP5 NCAPG2 BUB1 HERC5 KIF2C

1.27e-0418611650067eb78d4c7e32b9563550d9fcaf13445ee6a48
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

ANKFY1 RNF213 DNA2 INVS DOP1B

1.27e-0418611658571956890fc9894d766ba294a28e376b4aba428
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SZT2 NFASC MAGI2 NACC2 ST18

1.27e-041861165bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LETM2 BHLHE40 P2RX1 NMT2 P2RY14

1.30e-041871165bdcef4f3e093c3646b639a189bbe93d6f4c40f3c
Drug4-hydroxybenzoic acid

AKR1C1 AKR1C2 TYR AKR1C3

7.90e-0891164ctd:C038193
Drugcyclopentanol

AKR1C1 AKR1C2 AKR1C3

1.29e-0731163ctd:C016327
Drugcyclopentanone

AKR1C1 AKR1C2 AKR1C3

1.29e-0731163ctd:C007201
Drug4-benzoylbenzoic acid

AKR1C1 AKR1C2 AKR1C3

1.29e-0731163ctd:C058818
Drugdichloro(4-cymene)ruthenium(II)

AKR1C1 AKR1C2 AKR1C3

1.29e-0731163ctd:C530610
Drugcloxazolam

AKR1C1 AKR1C2 AKR1C3

5.14e-0741163ctd:C005522
DrugPregnanes

AKR1C1 AKR1C2 AKR1C3

5.14e-0741163ctd:D011278
Drugtetralol

AKR1C1 AKR1C2 AKR1C3

5.14e-0741163ctd:C019106
Druggliquidone

AKR1C1 AKR1C2 AKR1C3

5.14e-0741163ctd:C010969
Drug3',3'',5',5''-tetrabromophenolphthalein

AKR1C1 AKR1C2 AKR1C3

5.14e-0741163ctd:C018156
DrugHydroxysteroids

AKR1C1 AKR1C2 AKR1C3

1.28e-0651163ctd:D006914
DrugNSC86000

AKR1C1 AKR1C2 AKR1C3

1.28e-0651163CID000257630
Drugcresolphthalein

AKR1C1 AKR1C2 AKR1C3

1.28e-0651163ctd:C010092
DrugEstazolam

AKR1C1 AKR1C2 AKR1C3

2.55e-0661163ctd:D004949
DrugGlipizide

AKR1C1 AKR1C2 AKR1C3

2.55e-0661163ctd:D005913
Drugacenaphthene-1-ol

AKR1C1 AKR1C2 AKR1C3

2.55e-0661163ctd:C023723
DrugMedazepam

AKR1C1 AKR1C2 AKR1C3

2.55e-0661163ctd:D008472
Drug4-hydroxyequilenin-o-quinone

AKR1C1 AKR1C2 AKR1C3

4.44e-0671163ctd:C117714
Drugzomepirac

AKR1C1 AKR1C2 AKR1C3

4.44e-0671163ctd:C020549
DrugNitrazepam

AKR1C1 AKR1C2 AKR1C3

7.08e-0681163ctd:D009567
DrugPhenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; MCF7; HT_HG-U133A

POMT2 HIP1 ANKFY1 KDM4C IQSEC2 NMT2 ZMYM6 BAHCC1

7.51e-0619611683217_DN
DrugPepstatin A [26305-03-3]; Up 200; 5.8uM; MCF7; HT_HG-U133A

POMT2 ITPR1 THOP1 ZMIZ2 ZER1 BAIAP3 ZMYM6 HERC5

8.39e-0619911683264_UP
Drug20-alpha-Dihydroprogesterone

AKR1C1 AKR1C2 AKR1C3

1.06e-0591163ctd:D004092
DrugNSC36919

CYP11A1 AKR1C1 AKR1C2 SLCO1A2 AKR1C3

1.16e-05581165CID000235496
Drugoctyl gallate

AKR1C1 AKR1C2 AKR1C3

1.51e-05101163ctd:C016627
DrugDihydroxydihydrobenzopyrenes

AKR1C1 AKR1C2 AKR1C3

2.06e-05111163ctd:D004101
Drugchlordecone alcohol

AKR1C1 AKR1C2 AKR1C3

2.06e-05111163CID000013946
Drugalpha-methylcinnamic acid

AKR1C1 AKR1C3

2.57e-0521162ctd:C510582
Drug(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE

AKR1C1 AKR1C2

2.57e-0521162DB07768
Drugbaccharin

AKR1C2 AKR1C3

2.57e-0521162ctd:C012764
Drugfenamic acid

AKR1C1 AKR1C2 AKR1C3

2.74e-05121163ctd:C001209
DrugPhenolphthalein

AKR1C1 AKR1C2 AKR1C3

2.74e-05121163ctd:D020113
Drugresveratrol; Down 200; 10uM; MCF7; HT_HG-U133A_EA

KPNA4 ERCC6L ST3GAL1 URB2 THOP1 ZMIZ2 BUB1

3.49e-051771167841_DN
DrugDMBA-3,4-dihydrodiol

AKR1C1 AKR1C2 AKR1C3

3.55e-05131163CID000050096
Drugflunisolide

AKR1C1 AKR1C2 AKR1C3

3.55e-05131163ctd:C007734
DrugPrimaquine diphosphate [63-45-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A

POMT2 ST3GAL1 F3 BHLHE40 ITPR1 AKR1C3 ZER1

3.88e-0518011673279_UP
Drugstaurosporine; Down 200; 1uM; MCF7; HG-U133A

ZNF142 SETX ERCC6L URB2 BHLHE40 NACC2 HERPUD1

4.02e-051811167312_DN
DrugDydrogesterone

AKR1C1 AKR1C2 AKR1C3

4.50e-05141163ctd:D004394
Drug5-alpha-Dihydroprogesterone

AKR1C1 AKR1C2 AKR1C3

4.50e-05141163ctd:D043582
Drug1-acenaphthenol

AKR1C1 AKR1C2 AKR1C3

4.50e-05141163CID000022750
DrugMeclofenamic Acid

AKR1C1 AKR1C2 AKR1C3

4.50e-05141163ctd:D008469
DrugMefenamic Acid

AKR1C1 AKR1C2 TYR AKR1C3

4.58e-05391164ctd:D008528
Drug20 alpha-dihydroprogesterone

CYP11A1 AKR1C1 AKR1C2 AKR1C3

5.07e-05401164CID000008956
Drugglycidamide

MRE11 KDM4C ST3GAL1 AKR1C1 AKR1C2 AKR1C3

5.48e-051301166ctd:C071834
DrugNAD

AKR1C1 AKR1C2 ITPR1 TYR AKR1C3

5.58e-05801165ctd:D009243
Drugo-quinone

AKR1C1 AKR1C2 TYR AKR1C3

5.60e-05411164CID000011421
DrugClomiphene citrate (Z,E) [50-41-9]; Up 200; 6.6uM; MCF7; HT_HG-U133A

KDM4C IQSEC2 BHLHE40 ITPR1 ZMIZ2 BUB1 HERC5

6.44e-0519511672624_UP
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A

CCNJL ANKFY1 SETX SZT2 RIN1 UBA6 BAHCC1

6.44e-0519511673721_DN
DrugPhenformin hydrochloride [834-28-6]; Up 200; 16.6uM; PC3; HT_HG-U133A

ANKFY1 SZT2 MPDU1 BHLHE40 RIN1 BUB1 BAIAP3

6.65e-0519611674283_UP
DrugApomorphine hydrochloride hemihydrate [41372-20-7]; Up 200; 6.4uM; PC3; HT_HG-U133A

EXO5 BHLHE40 STAT2 ZER1 PRKG1 INVS DOP1B

6.87e-0519711676683_UP
DrugMetolazone [17560-51-9]; Up 200; 11uM; MCF7; HT_HG-U133A

CCNJL POMT2 EXO5 KDM4C MAP3K1 BUB1 DNA2

6.87e-0519711671514_UP
Drug9-cis-retinal

AKR1C1 TYR AKR1C3

6.88e-05161163ctd:C031390
DrugIsradipine [75695-93-1]; Up 200; 10.8uM; PC3; HT_HG-U133A

KDM4C IQSEC2 ITPR1 SLCO1A2 ZMIZ2 BUB1 BAIAP3

7.09e-0519811676347_UP
DrugIobenguane sulfate; Up 200; 10.8uM; HL60; HG-U133A

ZNF142 SETX SZT2 MPDU1 ZNF248 ZER1 HERC5

7.32e-0519911671729_UP
DrugNitrocaramiphen hydrochloride; Down 200; 10.8uM; HL60; HT_HG-U133A

HIP1 ANKFY1 KDM4C MAP3K1 MAGI2 RIN1 NMT2

7.32e-0519911673125_DN
DrugDanazol [17230-88-5]; Up 200; 11.8uM; PC3; HG-U133A

MBTPS1 ZNF142 MPDU1 ST3GAL1 BHLHE40 AKR1C3 HERPUD1

7.32e-0519911671954_UP
Drug5-dihydrodeoxycorticosterone

AKR1C1 AKR1C2

7.69e-0531162ctd:C454687
Drug4-cyanobenzaldehyde

F3 TYR

7.69e-0531162CID000066042
Drugnaphthalene-1,2-dihydrodiol

AKR1C1 AKR1C2 TYR AKR1C3

8.11e-05451164CID000000362
Drugbenzo(a)pyrene-1,6-quinone

AKR1C1 AKR1C2 AKR1C3

8.32e-05171163ctd:C030233
Drughelenalin

IL12A MBTPS1 KAT5 AKR1C1 ITPR1

9.29e-05891165CID000023205
Drugcloxazolam

AKR1C1 AKR1C2 AKR1C3

9.94e-05181163CID000002816
DrugRuthenium Compounds

AKR1C1 AKR1C2 AKR1C3

9.94e-05181163ctd:D017975
Drugbenzo(a)pyrene-3,6-quinone

AKR1C1 AKR1C2 AKR1C3

9.94e-05181163ctd:C018003
Drugoxcarbazepine

AKR1C1 AKR1C2 AKR1C3

1.18e-04191163ctd:C036006
Drugandrostane-3,17-dione

CYP11A1 AKR1C1 AKR1C2 AKR1C3

1.33e-04511164CID000000443
Drugbenzo(a)pyrene-7,8-dione

AKR1C1 AKR1C2 AKR1C3

1.38e-04201163ctd:C076588
DrugMRS2159

F3 MYLK2 P2RX1

1.38e-04201163CID006258690
DrugChrysenes

AKR1C1 AKR1C2 AKR1C3

1.38e-04201163ctd:D002911
Drug1,1,1-trichloroethane

MRE11 SETX PSMC1 F3 FANCD2 CRAMP1

1.50e-041561166CID000006278
Drugtetrahydrodeoxycorticosterone

AKR1C1 AKR1C2

1.53e-0441162ctd:C009413
DrugDBD-H

AKR1C1 AKR1C3

1.53e-0441162CID000131382
Drugcadmium sulfate

TNPO1 TTC4 BHLHE40 AKR1C1 AKR1C2 ST18 HERPUD1 MXD1

1.57e-043011168ctd:C037123
DrugFlunitrazepam

AKR1C1 AKR1C2 AKR1C3

1.60e-04211163ctd:D005445
Drugconiferaldehyde

AKR1C1 AKR1C2 AKR1C3

1.60e-04211163ctd:C075384
DrugDutasteride

AKR1C1 AKR1C2 AKR1C3

1.60e-04211163ctd:D000068538
DrugEugenol

IL12A AKR1C1 AKR1C2 TYR BUB1 AKR1C3 MXD1

1.75e-042291167ctd:D005054
DrugCTK2I5299

IL12A F3 P2RX1 P2RY14

1.79e-04551164CID005310955
Drugbenzene dihydrodiol

AKR1C1 AKR1C2 AKR1C3

1.85e-04221163CID000000418
Drug1,2-dihydroxynaphthalene

AKR1C1 AKR1C2 TYR AKR1C3

2.05e-04571164CID000011318
DrugSodium Dodecyl Sulfate

AKR1C1 AKR1C2 MAP3K1 AKR1C3 MXD1

2.12e-041061165ctd:D012967
Drug2'-Monophosphoadenosine 5'-Diphosphoribose

AKR1C1 AKR1C2 AKR1C3

2.12e-04231163DB03461
Drugmedazepam

AKR1C1 AKR1C2 AKR1C3

2.41e-04241163CID000004041
DrugGlycyrrhetinic Acid

AKR1C1 AKR1C2 AKR1C3

2.41e-04241163ctd:D006034
Drugfarnesal

AKR1C2 AKR1C3

2.55e-0451162ctd:C084519
Drug9,10-phenanthrenequinone

AKR1C1 AKR1C2 AKR1C3

2.73e-04251163ctd:C005399
DrugPregnanolone

AKR1C1 AKR1C2 AKR1C3

2.73e-04251163ctd:D011280
DiseaseNeoplasms, Hormone-Dependent

AKR1C1 AKR1C2 AKR1C3

4.90e-0831093C0027661
DiseaseHermaphroditism

AKR1C1 AKR1C2 AKR1C3

4.88e-0751093C0019269
DiseaseAmbiguous Genitalia

AKR1C1 AKR1C2 AKR1C3

4.88e-0751093C0266362
DiseasePseudohermaphroditism

AKR1C1 AKR1C2 AKR1C3

4.88e-0751093C0033804
DiseaseIntersex Conditions

AKR1C1 AKR1C2 AKR1C3

4.88e-0751093C2930618
DiseaseSex Differentiation Disorders

AKR1C1 AKR1C2 AKR1C3

4.88e-0751093C2930619
DiseaseDisorders of Sex Development

AKR1C1 AKR1C2 AKR1C3

1.70e-0671093C0036875
DiseaseCerebellar Hemiataxia

RFC1 SNX14

8.07e-0541092C0750994
DiseaseCerebellar Dysmetria

RFC1 SNX14

8.07e-0541092C0234162
DiseaseHypermetria (finding)

RFC1 SNX14

8.07e-0541092C3668822
DiseaseAdiadochokinesis

RFC1 SNX14

8.07e-0541092C0234357
DiseaseCerebellar Ataxia

RFC1 SNX14

1.34e-0451092C0007758
Diseasehypogonadism (biomarker_via_orthology)

CYP11A1 PRKG1

1.34e-0451092DOID:1924 (biomarker_via_orthology)
Diseasecortolone glucuronide (1) measurement

AKR1C2 AKR1C3

2.01e-0461092EFO_0800552
DiseaseNEPHRONOPHTHISIS 2

ZNF423 INVS

3.73e-0481092C1865872
Diseaserectum cancer (is_implicated_in)

MRE11 MAP3K1

4.79e-0491092DOID:1993 (is_implicated_in)
DiseaseB-lymphoblastic leukemia/lymphoma (is_implicated_in)

F3 AKR1C3

5.97e-04101092DOID:0080630 (is_implicated_in)
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

KDM4C CHRNA5 MAP3K1

6.21e-04451093DOID:3748 (is_implicated_in)
DiseaseEndometrial Neoplasms

CYP11A1 AKR1C1 AKR1C3

1.31e-03581093C0014170
Diseasevision disorder

F3 MAGI2

1.57e-03161092MONDO_0021084
Diseaseresponse to methotrexate

AKR1C1 AKR1C2

1.57e-03161092GO_0031427
Diseaseposterior cingulate cortex volume measurement

SLC37A1 KDM4C

1.77e-03171092EFO_0010324
Diseasesensorineural hearing loss (implicated_via_orthology)

LNX2 LNX1

2.22e-03191092DOID:10003 (implicated_via_orthology)
DiseaseEndometrial Carcinoma

CYP11A1 AKR1C1 AKR1C3

2.43e-03721093C0476089
Diseasecoagulation factor measurement

F3 PCID2

2.46e-03201092EFO_0004634
Diseaseserum metabolite measurement

TNPO1 KDM4C CKAP5 ST3GAL1 MAGI2 NWD2 SLCO1A2 AKR1C3 LNX1 HERPUD1

2.65e-0394510910EFO_0005653
Diseasepulmonary function measurement

SRP72 CHRNA5 ITPR1

2.94e-03771093EFO_0003892
DiseaseCCL24 measurement

HIP1 MAGI2

2.98e-03221092EFO_0009418
DiseaseEndometrioma

AKR1C1 AKR1C2 AKR1C3 HERC5

3.05e-031611094C0269102
DiseaseEndometriosis

AKR1C1 AKR1C2 AKR1C3 HERC5

3.05e-031611094C0014175
DiseaseAlcoholic Intoxication, Chronic

RFC1 CHRNA5 AKR1C3 ST18 HERPUD1

3.23e-032681095C0001973
Diseasecotinine measurement

CCNJL CHRNA5

3.25e-03231092EFO_0007813

Protein segments in the cluster

PeptideGeneStartEntry
CLKTLISLNHLILEP

URB2

411

Q14146
ALPRKAITHLKKRSC

ACTL10

71

Q5JWF8
RPKHLTSCLLNTKVL

BAHCC1

276

Q9P281
CHHLPSLDLLRQKLK

BUB1

1041

O43683
LLPQFLLHLDKIRKC

CARNMT1

101

Q8N4J0
VHRLELLLKCLGKLQ

BAIAP3

531

O94812
LCALAKKHKRTPALI

AKR1C3

241

P42330
CIAQLKDLLPEHLKL

BHLHE40

71

O14503
LENPCSLKHLCRLKI

ASB15

531

Q8WXK1
HCTLREKELKLPTFR

CCNJL

16

Q8IV13
LTLADCNLLPKLHII

CLIC6

636

Q96NY7
LPNKHGILQKLRCLI

NWD2

546

Q9ULI1
VVSSLPKLRHLLLEC

NWD2

921

Q9ULI1
LAPLLKDILKASLAH

RUBCNL

576

Q9H714
KLPHCRKLVLLCFLL

PCDHGA2

6

Q9Y5H1
KLLLDHQCLRDLLPK

HERPUD1

61

Q15011
KVAAIRKSPFILLHC

KCNH3

206

Q9ULD8
LELLSEHLDPKLLCR

LRWD1

31

Q9UFC0
RLLCHKCSTKEIPII

ANKFY1

1131

Q9P2R3
ASLIHHTKLCLEKPL

EXO5

236

Q9H790
PLLKLVCIDTHTLGL

OR4C12

181

Q96R67
LHRVKPAVCSLLPKE

KLHL36

246

Q8N4N3
LEHLDRPQLVALCKL

LETM2

286

Q2VYF4
KEHLEHLLRCLKNPL

PRAMEF17

281

Q5VTA0
HLRLCLEKLKGLVPL

MXD1

71

Q05195
DVLAVIKHCKDPLRL

MAGI2

81

Q86UL8
CVHKKLRSKRVAPVL

NMT2

251

O60551
IWLLLLVVLLCGKKH

MBTPS1

6

Q14703
LRLTKILLAILDCVH

ITPR1

886

Q14643
LKRKLHKCQSVLPVP

PRKG1

36

Q13976
LLISKRLAQCLHPAL

DOP1B

61

Q9Y3R5
KKPVLSLPHRRLVCC

IQSEC2

961

Q5JU85
RLLRIDSKCLHFTPK

KAT5

491

Q92993
CDLHIIKREALLKVL

KCNH5

636

Q8NCM2
ILVHKLLDKLLVLCP

LNX2

101

Q8N448
RVLHLDLKPENILCV

MYLK2

401

Q9H1R3
LLRDILHKTVKHPVC

EEF2KMT

46

Q96G04
IPLQRLKLKCIFCRH

KDM4C

801

Q9H3R0
KLLNKLLVTCPFREH

LNX1

96

Q8TBB1
VLKLHPCLAPIKVAL

POLG2

371

Q9UHN1
LKHPKCLLESLRLDC

NLRP5

861

P59047
TKIKLCILLHAFRIR

IL12A

191

P29459
LLKHVPKIIHLVCKL

PTPDC1

281

A2A3K4
PKIIHLVCKLLLDLA

PTPDC1

286

A2A3K4
TFLLPREKQLREHCK

CCDC182

116

A6NF36
SCLLNLIRKPHIGLT

EXOC6

531

Q8TAG9
TTCLKDNLLKRLPFH

HERC5

466

Q9UII4
LECRVKHDPSLKLTV

NFASC

541

O94856
KINKLHLCKPLIRAI

PCID2

181

Q5JVF3
LLFLIRLIHKELSCP

SLC37A1

506

P57057
LVRKIFLHTLPKLLC

CHRNA5

351

P30532
PIRTLKTLLHTLCKL

CKAP5

1756

Q14008
TLCKLKGPKILDHLT

CKAP5

1766

Q14008
LRCLVDKLESLPLHK

KDM2A

461

Q9Y2K7
PTALHKQRLLSCLLK

CRAMP1

721

Q96RY5
IAKCPLRTKTGHILK

CCDC66

41

A2RUB6
LLKASIKETLRLHPI

CYP11A1

376

P05108
RAKHKLILLGCVPSL

DNA2

1006

P51530
LKLKCVAHLGRTKVL

CFAP47

941

Q6ZTR5
ISIPSKCLLLVHEPK

KIF2C

281

Q99661
VLKKLCDHPRLLSAR

ERCC6L

406

Q2NKX8
HVPLLKKTLELLVCR

FANCD2

1356

Q9BXW9
IISFQHLKRLTCLKL

LRRC8D

676

Q7L1W4
TTRHRSPKCLALLLK

INVS

121

Q9Y283
PCHSLAERIKLQRLL

MAP3K1

666

Q13233
TVLCDLLLLHILPKR

P2RX1

346

P51575
LLLKHCAPVLAKLRP

TAF6

426

P49848
RPCLVVLHKPLDKLL

SZT2

736

Q5T011
VLEKSLHCSVLKPLR

RIN1

431

Q13671
HLRQLLKELKGLSCL

STAT2

271

P52630
GKHLTARVLCLIVLP

POMT2

276

Q9UKY4
RLHKVVRKLVPSCDV

HKDC1

426

Q2TB90
IVTRKLHSIKCKPPL

LCMT1

126

Q9UIC8
LIKRPCKVKTIHLLT

MITD1

141

Q8WV92
ELIGLIKHTKIPIIC

RFC1

736

P35251
KLLFKLHSCLPADTL

HIP1

241

O00291
LEEHSKLIAKVRCLP

SMARCAL1

376

Q9NZC9
LPHLKKLTTLLCKEL

INPP5D

206

Q92835
LSENLKRLIKHRPCT

ST3GAL1

46

Q11201
LCLLPLIVKHIRKKQ

SIGLECL1

131

Q8N7X8
TLTPLIHRCNKLILV

SETX

2191

Q7Z333
PLLEPLICKKIAHER

WDR20

521

Q8TBZ3
LICKKIAHERLTVLI

WDR20

526

Q8TBZ3
ALIILILLRKCHLPG

SLCO1A2

616

P46721
LVTPHTQCRLKLLKL

PSMC1

51

P62191
KACLILRSIEELKHK

SRP72

391

O76094
KPSRKTLHTCLELLR

MRE11

66

P49959
PFREILCKKLHIPLK

P2RY14

301

Q15391
DLLHVPCLKILLSKG

MPDU1

31

O75352
KLHARDLKKELITCP

ST18

711

O60284
LCALAKKHKRTPALI

AKR1C1

241

Q04828
LCALAKKHKRTPALI

AKR1C2

241

P52895
CLLSAPRKKLNHLLK

NCAPG2

776

Q86XI2
DKLPRHKKLERLCLT

RNF213

2366

Q63HN8
HKKLERLCLTLGIPQ

RNF213

2371

Q63HN8
LQLLHCFPLDIRLKD

UBA6

716

A0AVT1
KLCLLLTLPRLTNHA

WDR47

136

O94967
LRALKLVITALKCHK

ZER1

391

Q7Z7L7
LALLCSEKPTHSLLR

ZFR2

676

Q9UPR6
KVKCKRHRPSLLLEN

SNX14

106

Q9Y5W7
LPINSRKCLREEIHK

TMED10

36

P49755
LKRKKDPPLSITHCR

IGSF9B

756

Q9UPX0
LLAGLVSLLCRHKRK

TYR

491

P14679
VSLLCRHKRKQLPEE

TYR

496

P14679
LVIILAISLHKCRKA

F3

266

P13726
SLHLKKIIVVSRLCG

TTC21A

296

Q8NDW8
ICKDVLVRHLPKLIP

TNPO1

296

Q92973
KRLLPAEHCITKIKR

ZMIZ2

556

Q8NF64
CGLFLILLALHRAKK

ZDHHC23

176

Q8IYP9
RLVAEKLSPCLHKIL

ZMYM6

1016

O95789
CHPLLLLNSESKKPR

PLEKHG7

211

Q6ZR37
PVFHCLKVLVPKLLT

TARBP1

946

Q13395
LKLHLELLLRKQACP

ZNF423

651

Q2M1K9
LSTHLLKKCPVLLRK

ZNF142

881

P52746
EIRSCLPKLLLAHHK

XPO6

86

Q96QU8
PLLKKCHVPETRRKV

THOP1

226

P52888
TAARKLKPCHLKAII

TTC4

141

O95801
LKAIIRGALCHLELK

TTC4

151

O95801
CEKLLLDIRHEKIPI

ZNF248

171

Q8NDW4
LLLRKPVRLKCHPLA

TRERF1

866

Q96PN7
IKSGILPILVHCLER

KPNA4

111

O00629
EALKHPECKLQTLRL

NLRP14

751

Q86W24
LCAGVKHKVLLRRLL

NACC2

366

Q96BF6