Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnetrin receptor activity

UNC5B UNC5D

1.55e-046652GO:0005042
GeneOntologyMolecularFunctionintegrin binding

TNC ITGA8 ITGAD ITGAX TNXB

2.64e-04175655GO:0005178
GeneOntologyMolecularFunctionextracellular matrix structural constituent

RELN TNC TECTA TNXB COL1A2

3.67e-04188655GO:0005201
GeneOntologyBiologicalProcesscell-matrix adhesion

PKD1 MKLN1 ITGA8 TECTA ITGAD ITGAX TNXB

2.22e-05270657GO:0007160
GeneOntologyBiologicalProcessneuron projection development

SEMA4F RELN IGF1R MEGF8 TNC UNC5B SEMA4A TECTA USH1C SLC23A2 GALR2 TNXB UNC5D ARF1

3.76e-0512856514GO:0031175
GeneOntologyBiologicalProcessregulation of synaptic activity

RELN SYBU

5.84e-054652GO:0060025
GeneOntologyCellularComponentprotein complex involved in cell adhesion

TNC ITGA8 ITGAD ITGAX TNXB

1.09e-0659655GO:0098636
GeneOntologyCellularComponentpostsynaptic specialization

SEMA4F SLC16A3 PCLO MKLN1 ITGA8 DAPK1 CHRNA4 ARF1 KPNA2

2.43e-05503659GO:0099572
GeneOntologyCellularComponenttenascin complex

TNC TNXB

5.69e-054652GO:0090733
GeneOntologyCellularComponentintegrin complex

ITGA8 ITGAD ITGAX

1.33e-0432653GO:0008305
GeneOntologyCellularComponentneuron to neuron synapse

SEMA4F SLC16A3 PCLO MKLN1 ITGA8 DAPK1 ARF1 KPNA2

2.10e-04523658GO:0098984
GeneOntologyCellularComponentpostsynaptic specialization membrane

SEMA4F SLC16A3 MKLN1 ITGA8 CHRNA4

4.05e-04201655GO:0099634
GeneOntologyCellularComponentpostsynaptic density

SEMA4F SLC16A3 PCLO ITGA8 DAPK1 ARF1 KPNA2

4.92e-04451657GO:0014069
GeneOntologyCellularComponentasymmetric synapse

SEMA4F SLC16A3 PCLO ITGA8 DAPK1 ARF1 KPNA2

6.85e-04477657GO:0032279
GeneOntologyCellularComponentpostsynapse

SEMA4F IGF1R SLC16A3 PCLO MKLN1 ITGA8 DAPK1 CHRNA4 ARF1 KPNA2

1.12e-0310186510GO:0098794
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

TNC TNXB

1.26e-0317652GO:0098637
DomainPSI

SEMA4F MEGF8 PLXDC1 SEMA4A

3.69e-0632624PF01437
DomainPlexin_repeat

SEMA4F MEGF8 PLXDC1 SEMA4A

3.69e-0632624IPR002165
DomainIntegrin_alpha

ITGA8 ITGAD ITGAX

5.64e-0611623PF00357
DomainPSI

SEMA4F MEGF8 PLXDC1 SEMA4A

1.62e-0546624SM00423
DomainIntegrin_alpha_C_CS

ITGA8 ITGAD ITGAX

1.89e-0516623IPR018184
DomainIntegrin_alpha-2

ITGA8 ITGAD ITGAX

2.74e-0518623IPR013649
DomainIntegrin_alpha2

ITGA8 ITGAD ITGAX

2.74e-0518623PF08441
DomainIntegrin_alpha

ITGA8 ITGAD ITGAX

2.74e-0518623IPR000413
DomainINTEGRIN_ALPHA

ITGA8 ITGAD ITGAX

2.74e-0518623PS00242
DomainInt_alpha_beta-p

ITGA8 ITGAD ITGAX

3.25e-0519623IPR013519
DomainInt_alpha

ITGA8 ITGAD ITGAX

3.25e-0519623SM00191
DomainFG_GAP

ITGA8 ITGAD ITGAX

5.13e-0522623PS51470
DomainROC_dom

DAPK1 LRRK1

6.48e-054622IPR020859
DomainROC

DAPK1 LRRK1

6.48e-054622PS51424
DomainFG-GAP

ITGA8 ITGAD ITGAX

6.71e-0524623PF01839
DomainFG-GAP

ITGA8 ITGAD ITGAX

6.71e-0524623IPR013517
DomainIntegrin_dom

ITGA8 ITGAD ITGAX

7.61e-0525623IPR032695
DomainDEATH

UNC5B DAPK1 UNC5D

9.63e-0527623SM00005
DomainUPA

UNC5B UNC5D

1.08e-045622IPR033772
DomainUPA

UNC5B UNC5D

1.08e-045622PF17217
DomainWD40/YVTN_repeat-like_dom

SEMA4F SF3B3 SMU1 WDR73 SEMA4A LRBA WDTC1

1.18e-04335627IPR015943
DomainDeath

UNC5B DAPK1 UNC5D

1.77e-0433623PF00531
DomainDeath_domain

UNC5B DAPK1 UNC5D

2.71e-0438623IPR000488
DomainDEATH_DOMAIN

UNC5B DAPK1 UNC5D

2.71e-0438623PS50017
DomainZU5

UNC5B UNC5D

3.85e-049622SM00218
DomainPSI

SEMA4F MEGF8 SEMA4A

4.19e-0444623IPR016201
DomainWD40_repeat_dom

SF3B3 SMU1 WDR73 LRRK1 LRBA WDTC1

4.48e-04297626IPR017986
DomainZU5

UNC5B UNC5D

4.80e-0410622PS51145
DomainCTLH_C

MKLN1 SMU1

4.80e-0410622IPR006595
DomainCTLH

MKLN1 SMU1

4.80e-0410622PS50897
DomainZU5

UNC5B UNC5D

7.00e-0412622PF00791
DomainZU5_dom

UNC5B UNC5D

7.00e-0412622IPR000906
Domain-

SEMA4F SMU1 WDR73 SEMA4A LRBA WDTC1

8.15e-043336262.130.10.10
DomainEGF_extracell

RELN TNC TNXB

1.04e-0360623IPR013111
DomainEGF_2

RELN TNC TNXB

1.04e-0360623PF07974
DomainEGF

RELN MEGF8 TNC TECTA TNXB

1.09e-03235625SM00181
DomainEGF-like_dom

RELN MEGF8 TNC TECTA TNXB

1.41e-03249625IPR000742
DomainGrowth_fac_rcpt_

IGF1R MEGF8 TNC TNXB

1.79e-03156624IPR009030
DomainSemaphorin

SEMA4F SEMA4A

1.98e-0320622IPR027231
DomainFibrinogen_a/b/g_C_2

TNC TNXB

2.85e-0324622IPR014715
Domain-

TNC TNXB

2.85e-03246224.10.530.10
DomainFibrinogen_C

TNC TNXB

3.61e-0327622PF00147
Domain-

UNC5B DAPK1 UNC5D

3.66e-03936231.10.533.10
DomainLisH

MKLN1 SMU1

3.88e-0328622SM00667
DomainLisH

MKLN1 SMU1

3.88e-0328622IPR006594
DomainLISH

MKLN1 SMU1

3.88e-0328622PS50896
DomainARF

ARF1 ARF3

4.16e-0329622PS51417
DomainFBG

TNC TNXB

4.16e-0329622SM00186
DomainSmall_GTPase_ARF

ARF1 ARF3

4.16e-0329622IPR024156
DomainDEATH-like_dom

UNC5B DAPK1 UNC5D

4.36e-0399623IPR011029
Domain-

TNC TNXB

4.44e-03306223.90.215.10
DomainFibrinogen_a/b/g_C_1

TNC TNXB

4.44e-0330622IPR014716
DomainSema

SEMA4F SEMA4A

4.74e-0331622SM00630
DomainSemap_dom

SEMA4F SEMA4A

4.74e-0331622IPR001627
DomainSema

SEMA4F SEMA4A

4.74e-0331622PF01403
DomainSEMA

SEMA4F SEMA4A

4.74e-0331622PS51004
DomainArf

ARF1 ARF3

4.74e-0331622PF00025
DomainFIBRINOGEN_C_1

TNC TNXB

5.04e-0332622PS00514
DomainFibrinogen_a/b/g_C_dom

TNC TNXB

5.04e-0332622IPR002181
DomainFIBRINOGEN_C_2

TNC TNXB

5.04e-0332622PS51406
DomainSmall_GTPase_ARF/SAR

ARF1 ARF3

5.36e-0333622IPR006689
PathwayREACTOME_ECM_PROTEOGLYCANS

TNC ITGA8 ITGAX TNXB COL1A2

8.43e-0747535MM14925
PathwayWP_FOCAL_ADHESION

RELN TNC ITGA8 ITGAD ITGAX TNXB COL1A2

5.95e-06187537MM15913
PathwayREACTOME_ECM_PROTEOGLYCANS

TNC ITGA8 ITGAX TNXB COL1A2

9.35e-0676535M27219
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

TNC ITGA8 ITGAD ITGAX COL1A2

9.35e-0676535MM14867
PathwayKEGG_ECM_RECEPTOR_INTERACTION

RELN TNC ITGA8 TNXB COL1A2

1.53e-0584535M7098
PathwayWP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING

RELN IGF1R TNC ITGA8 ITGAD ITGAX TNXB COL1A2

1.55e-05302538M39719
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

TNC ITGA8 ITGAD ITGAX COL1A2

1.62e-0585535M16441
PathwayWP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY

RELN IGF1R TNC ITGA8 ITGAD ITGAX TNXB COL1A2

2.69e-05326538MM15917
PathwayWP_FOCAL_ADHESION

RELN IGF1R TNC ITGA8 TNXB COL1A2

9.70e-05199536M39402
PathwayKEGG_FOCAL_ADHESION

RELN IGF1R TNC ITGA8 TNXB COL1A2

9.70e-05199536M7253
PathwayPID_INTEGRIN_CS_PATHWAY

ITGA8 ITGAD ITGAX

1.23e-0426533M47
PathwayWP_PI3KAKT_SIGNALING

RELN IGF1R TNC ITGA8 TNXB PCK1 COL1A2

2.60e-04339537M39736
PathwayREACTOME_NETRIN_MEDIATED_REPULSION_SIGNALS

UNC5B UNC5D

3.83e-048532M27328
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

TNC ITGA8 ITGAD ITGAX TNXB COL1A2

3.96e-04258536MM14572
PathwayREACTOME_CASPASE_ACTIVATION_VIA_DEPENDENCE_RECEPTORS_IN_THE_ABSENCE_OF_LIGAND

UNC5B DAPK1

6.12e-0410532M866
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

TNC ITGA8 ITGAD ITGAX TNXB COL1A2

8.75e-04300536M610
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

IGF1R ITGA8 ITGAD ITGAX

1.09e-03121534M39823
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA4F IGF1R MEGF8 SIPA1L3 ENTPD2 PKD1 HELZ2 LRRK1 SLC45A1 LRBA BCL2L13 D2HGDH KCNH3

1.11e-071105651335748872
Pubmed

An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.

SEMA4F UNC5B SEMA4A UNC5D

2.81e-065265426633812
Pubmed

Characterization of the human gene encoding ADP-ribosylation factor 1, a guanine nucleotide-binding activator of cholera toxin.

ARF1 ARF3

3.44e-0626521577740
Pubmed

Assignment of human ADP ribosylation factor (ARF) genes ARF1 and ARF3 to chromosomes 1q42 and 12q13, respectively.

ARF1 ARF3

3.44e-0626528661066
Pubmed

Resveratrol inhibits collagen I synthesis by suppressing IGF-1R activation in intestinal fibroblasts.

IGF1R COL1A2

3.44e-06265224782617
Pubmed

Molecular cloning, characterization, and expression of human ADP-ribosylation factors: two guanine nucleotide-dependent activators of cholera toxin.

ARF1 ARF3

3.44e-0626522474826
Pubmed

The tenascin gene family in axon growth and guidance.

TNC TNXB

3.44e-0626529321695
Pubmed

Mapping of the human CD11c (ITGAX) and CD11d (ITGAD) genes demonstrates that they are arranged in tandem separated by no more than 11.5 kb.

ITGAD ITGAX

3.44e-0626529598326
Pubmed

Tenascin C interacts with ecto-5'-nucleotidase (eN) and regulates adenosine generation in cancer cells.

TNC NT5E

3.44e-06265218062933
Pubmed

Tenascin-X expression in tumor cells and fibroblasts: glucocorticoids as negative regulators in fibroblasts.

TNC TNXB

3.44e-0626528856503
Pubmed

Characterization of ecto-nucleotidases in human oviducts with an improved approach simultaneously identifying protein expression and in situ enzyme activity.

NT5E ENTPD2

3.44e-06265229273916
Pubmed

ARF1 and ARF3 are required for the integrity of recycling endosomes and the recycling pathway.

ARF1 ARF3

3.44e-06265222971977
Pubmed

Invasion of melanoma in double knockout mice lacking tenascin-X and tenascin-C.

TNC TNXB

3.44e-06265212359049
Pubmed

The genes coding for phosphoenolpyruvate carboxykinase-1 (PCK1) and neuronal nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4) map to human chromosome 20, extending the known region of homology with mouse chromosome 2.

CHRNA4 PCK1

3.44e-0626521492743
Pubmed

Microarray-based identification of tenascin C and tenascin XB, genes possibly involved in tumorigenesis associated with neurofibromatosis type 1.

TNC TNXB

3.44e-06265217202312
Pubmed

The change in tenascin expression in mouse uterus during early pregnancy.

TNC TNXB

3.44e-0626529013311
Pubmed

Distribution of tenascin-C and -X, and soft X-ray analysis of the mandibular symphysis during mandible formation in the human fetus.

TNC TNXB

3.44e-06265215455729
Pubmed

Metalloproteinase PAPP-A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis.

PKD1 PAPPA

3.44e-06265231990681
Pubmed

Tenascin variants: ligands and expression.

TNC TNXB

3.44e-0626527509489
Pubmed

The effects of tenascin C knockdown on trabecular meshwork outflow resistance.

TNC TNXB

3.44e-06265223882691
Pubmed

Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate.

RELN UNC5B UNC5D

9.35e-062265322726835
Pubmed

Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.

TNC TNXB COL1A2

9.35e-062265327527664
Pubmed

Obstructed migration of Purkinje cells in the developing cerebellum of the reeler mutant mouse.

RELN TNC

1.03e-0536527506500
Pubmed

Expression of tenascin in developing and adult mouse lymphoid organs.

TNC TNXB

1.03e-0536527687262
Pubmed

The tenascin gene family.

TNC TNXB

1.03e-0536527530141
Pubmed

Tenascin-C, tenascin-R and tenascin-X: a family of talented proteins in search of functions.

TNC TNXB

1.03e-0536527694605
Pubmed

Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis.

ARF1 ARF3

1.03e-05365226330566
Pubmed

Murine tenascin-W: a novel mammalian tenascin expressed in kidney and at sites of bone and smooth muscle development.

TNC ITGA8

1.03e-05365214709716
Pubmed

Tenascins and osteopontin in biological response in cornea.

TNC TNXB

1.03e-05365237209968
Pubmed

Death-associated protein kinase 1 is an IRF3/7-interacting protein that is involved in the cellular antiviral immune response.

DAPK1 IRF3

1.03e-05365224531619
Pubmed

Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment.

DAPK1 LRRK1

1.03e-05365219712061
Pubmed

The dynamic expression of tenascin-C and tenascin-X during early heart development in the mouse.

TNC TNXB

1.03e-05365212823230
Pubmed

The integrin receptor alpha 8 beta 1 mediates interactions of embryonic chick motor and sensory neurons with tenascin-C.

TNC ITGA8

1.03e-0536527541634
Pubmed

USP22 promotes IRF3 nuclear translocation and antiviral responses by deubiquitinating the importin protein KPNA2.

IRF3 KPNA2

1.03e-05365232130408
Pubmed

ARF1 and ARF4 regulate recycling endosomal morphology and retrograde transport from endosomes to the Golgi apparatus.

ARF1 ARF3

1.03e-05365223783033
Pubmed

Interaction of the PDZ domain of human PICK1 with class I ADP-ribosylation factors.

ARF1 ARF3

1.03e-05365210623590
Pubmed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.

ITGA8 ITGAD ITGAX

1.76e-052765331541017
Pubmed

Developmental gene expression profiling along the tonotopic axis of the mouse cochlea.

TNC TECTA USH1C

1.97e-052865322808246
Pubmed

Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.

TECTA USH1C

2.06e-05465218849963
Pubmed

Increased expression of tenascin-C-binding epithelial integrins in human bullous keratopathy corneas.

TNC ITGA8

2.06e-05465211668187
Pubmed

A Novel Function of F-Box Protein FBXO17 in Negative Regulation of Type I IFN Signaling by Recruiting PP2A for IFN Regulatory Factor 3 Deactivation.

IRF3 FBXO17

2.06e-05465227956528
Pubmed

The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase.

UNC5B DAPK1

2.06e-05465215729359
Pubmed

Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion.

UNC5B UNC5D

2.06e-05465226235030
Pubmed

Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.

TNC ITGA8 KPNA2 COL1A2

2.52e-059065428535371
Pubmed

Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes.

ARF1 ARF3

3.43e-0556529038142
Pubmed

ADP-ribosylation factor is functionally and physically associated with the Golgi complex.

ARF1 ARF3

3.43e-0556522105501
Pubmed

Deficiency of CD11b or CD11d results in reduced staphylococcal enterotoxin-induced T cell response and T cell phenotypic changes.

ITGAD ITGAX

3.43e-05565215210787
Pubmed

Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis.

IGF1R PKD1

3.43e-05565211818962
Pubmed

Collagen and tenascin-C expression along the migration pathway of mouse primordial germ cells.

TNC COL1A2

3.43e-05565214758483
Pubmed

Phosphorylation of importin-α1 by CDK1-cyclin B1 controls mitotic spindle assembly.

KIFC1 KPNA2

3.43e-05565231434716
Pubmed

The human integrin alpha 8 beta 1 functions as a receptor for tenascin, fibronectin, and vitronectin.

TNC ITGA8

3.43e-0556527559467
Pubmed

CD11a regulates hematopoietic stem and progenitor cells.

ITGAD ITGAX

3.43e-05565237781399
Pubmed

CD11c regulates hematopoietic stem and progenitor cells under stress.

ITGAD ITGAX

3.43e-05565233351105
Pubmed

The distribution of tenascin-X is distinct and often reciprocal to that of tenascin-C.

TNC TNXB

3.43e-0556527512972
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

RELN TNC PKD1 TNXB COL1A2

4.71e-0521065516537572
Pubmed

The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase.

UNC5B DAPK1

5.13e-05665221172653
Pubmed

Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex.

RELN UNC5D

5.13e-05665225308109
Pubmed

Tenascin is induced at implantation sites in the mouse uterus and interferes with epithelial cell adhesion.

TNC TNXB

5.13e-0566527512897
Pubmed

Smad3 binds Scleraxis and Mohawk and regulates tendon matrix organization.

TNC COL1A2

7.18e-05765223653374
Pubmed

Cloning of three mouse Unc5 genes and their expression patterns at mid-gestation.

UNC5B UNC5D

7.18e-05765212351186
Pubmed

Peri-pubertal emergence of UNC-5 homologue expression by dopamine neurons in rodents.

UNC5B UNC5D

7.18e-05765220628609
Pubmed

Transforming Growth Factor-Beta and Sonic Hedgehog Signaling in Palatal Epithelium Regulate Tenascin-C Expression in Palatal Mesenchyme During Soft Palate Development.

TNC TNXB

7.18e-05765232581832
Pubmed

GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors.

ARF1 ARF3

7.18e-05765211950392
Pubmed

FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development.

UNC5B UNC5D

7.18e-05765225374360
Pubmed

Poly (ADP-Ribose) Polymerase 1 Regulates Cajal-Retzius Cell Development and Neural Precursor Cell Adhesion.

RELN TNC

7.18e-05765234708032
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH17 DNAH2

7.18e-05765231178125
Pubmed

The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons.

RELN IGF1R KCNH3

7.81e-054465327224923
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

SEMA4F RELN UNC5B UNC5D

9.37e-0512665416284245
Pubmed

Activation of Hypoxia Signaling in Stromal Progenitors Impairs Kidney Development.

NT5E ITGA8 COL1A2

9.53e-054765328527294
Pubmed

Cloning of two novel ADP-ribosylation factor-like proteins and characterization of their differential expression in 3T3-L1 cells.

ARF1 ARF3

9.56e-0586528195219
Pubmed

Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6).

ARF1 ARF3

9.56e-0586528947846
Pubmed

Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.

TOMM40 TNXB

9.56e-05865222694956
Pubmed

Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.

TECTA USH1C

9.56e-05865221165971
Pubmed

Mice develop normally without tenascin.

TNC TNXB

9.56e-0586521383086
Pubmed

A mouse model for dominant collagen VI disorders: heterozygous deletion of Col6a3 Exon 16.

TNXB COL1A2

9.56e-05865224563484
Pubmed

Expression analysis of type I ARF small GTPases ARF1-3 during mouse brain development.

ARF1 ARF3

9.56e-05865238227057
Pubmed

Neural bHLH genes control the neuronal versus glial fate decision in cortical progenitors.

RELN TNC

1.23e-04965211239431
Pubmed

Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain.

UNC5B UNC5D

1.23e-04965223457482
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

SF3B3 PCLO DAPK1 TOMM40 LRBA HYDIN ARF1 ARF3

1.28e-0480765830575818
Pubmed

Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos.

TNC COL1A2

1.53e-041065215162503
Pubmed

Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.

ADCY4 RELN

1.53e-041065216615126
Pubmed

Interaction of GRASP, a protein encoded by a novel retinoic acid-induced gene, with members of the cytohesin family of guanine nucleotide exchange factors.

ARF1 ARF3

1.53e-041065210828067
Pubmed

Extracellular matrix protein composition dynamically changes during murine forelimb development.

TNC COL1A2

1.87e-041165238303699
Pubmed

Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis.

UNC5B UNC5D

1.87e-041165215186747
Pubmed

Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling.

SLC16A3 UNC5B

1.87e-041165228576770
Pubmed

Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain.

RELN TNC

1.87e-04116529367432
Pubmed

Analysis of Netrin 1 receptors during inner ear development.

UNC5B UNC5D

1.87e-041165217616930
Pubmed

Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.

TECTA USH1C

1.87e-041165231776257
Pubmed

Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality in mice.

SLC16A3 COL1A2

1.87e-041165238318368
Pubmed

Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes.

PAPPA SLC45A1 UNC5D

2.18e-046265316368877
Pubmed

YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis.

TNC TNXB

2.24e-041265210101119
Pubmed

Widespread Differential Expression of Coding Region and 3' UTR Sequences in Neurons and Other Tissues.

UNC5B UNC5D

2.24e-041265226687222
Pubmed

Accelerated failure time models provide a useful statistical framework for aging research.

IGF1R PAPPA

2.24e-041265219007875
Pubmed

GORAB scaffolds COPI at the trans-Golgi for efficient enzyme recycling and correct protein glycosylation.

ARF1 ARF3

2.24e-041265230631079
Pubmed

FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons.

UNC5B UNC5D

2.24e-041265221673655
Pubmed

An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration.

SEMA4F SEMA4A

2.65e-041365224572910
Pubmed

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) and Spike (S) Proteins Antagonize Host Type I Interferon Response.

IRF3 KPNA2

2.65e-041365234950606
Pubmed

Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels.

ITGAD ITGAX

2.65e-041365220563599
Pubmed

The Mohawk homeobox gene is a critical regulator of tendon differentiation.

TNC COL1A2

2.65e-041365220498044
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

IGF1R PCLO PKD1 CHRNA4

3.02e-0417165420201926
Cytoband15q26.3

IGF1R LRRK1

1.56e-034165215q26.3
GeneFamilyCD molecules|Integrin alpha subunits

ITGA8 ITGAD ITGAX

1.39e-05184831160
GeneFamilyDyneins, axonemal

DNAH17 DNAH2

9.15e-0417482536
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA4F SEMA4A

1.27e-0320482736
GeneFamilyFibrinogen C domain containing

TNC TNXB

1.99e-0325482554
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

ARF1 ARF3

3.06e-0331482357
GeneFamilyCyclins|F-boxes other

FBXO3 FBXO17

4.80e-0339482560
GeneFamilyWD repeat domain containing

SMU1 WDR73 LRBA WDTC1

5.09e-03262484362
GeneFamilyPDZ domain containing

PCLO SIPA1L3 USH1C

7.64e-031524831220
GeneFamilyFibronectin type III domain containing

IGF1R TNC TNXB

8.79e-03160483555
CoexpressionGAVIN_FOXP3_TARGETS_CLUSTER_T4

IGF1R NT5E SMU1 SEMA4A ARF1

4.33e-0697655M1729
CoexpressionGAVIN_FOXP3_TARGETS_CLUSTER_T4

IGF1R NT5E SMU1 SEMA4A ARF1

5.03e-06100655MM1215
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PCLO PAPPA FBXO17 USH1C UNC5D PCK1

2.56e-07180656358923e4228035a3e90e2957392089219e90dcd7
ToppCellwk_20-22-Endothelial-Lymph_endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADCY4 RELN UNC5B PCLO BACE2 TNXB

3.63e-07191656631f95fd80dd3678b5b2ef201abf7fe646049af6
ToppCellwk_20-22-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADCY4 RELN UNC5B PCLO BACE2 TNXB

3.98e-07194656640ff8da7084a9486fc2752493b8d8059ecf4ab7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PCLO SIPA1L3 DAPK1 LRBA FBXO17 HYDIN

4.22e-071966566ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ADCY4 RELN UNC5B FBXO17 TNXB WDTC1

4.22e-07196656b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ADCY4 RELN UNC5B FBXO17 TNXB WDTC1

4.22e-07196656a31e227de2dc077b81881295b012d22fedbd65ed
ToppCellLymphoid-Lymphoid-NK_cells|Lymphoid / shred on cell class and cell subclass (v4)

LRRK1 SEMA4A ITGAD ITGAX B4GALT4

2.54e-06148655d51a4b654a88d58dcdf29c2bc362c0cc1c40723a
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

ADCY4 RELN NT5E FBXO17 TNXB

4.45e-06166655c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCelldroplet-Lung-nan-18m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F IGF1R NT5E FBXO17 TECTA

6.42e-061796558ebd0c7ac99ac8194fa1a2aac88a893739a97725
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNC PAPPA TNXB UNC5D COL1A2

6.59e-06180655f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F IGF1R NT5E FBXO17 TECTA

6.59e-0618065581c7086399256260e59424b7410feec514ce8027
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

PAPPA FBXO17 USH1C UNC5D PCK1

6.59e-06180655864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENTPD2 PAPPA BACE2 TNXB COL1A2

7.14e-0618365563294d66e3ccf152ffe5d1237106764c14390b62
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENTPD2 PAPPA BACE2 TNXB COL1A2

7.14e-061836557e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADCY4 RELN UNC5B BACE2 TNXB

7.14e-06183655bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RELN TNC PAPPA BACE2 COL1A2

7.53e-061856557dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TNC UNC5B TNXB COL1A2

7.53e-06185655f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell390C-Fibroblasts-Fibroblast-F|390C / Donor, Lineage, Cell class and subclass (all cells)

ENTPD2 FBXO17 TNXB CHRNA4 COL1A2

7.53e-061856552c1f14f77faeee2acb388d997c5a27a7fef79be1
ToppCell390C-Fibroblasts-Fibroblast-F-|390C / Donor, Lineage, Cell class and subclass (all cells)

ENTPD2 FBXO17 TNXB CHRNA4 COL1A2

7.53e-0618565537db8e0b1f59274227f6fc2362167eb44bd080ef
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TNC UNC5B TNXB COL1A2

7.53e-0618565540e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TNC UNC5B TNXB COL1A2

7.53e-061856555f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

PCLO PAPPA USH1C UNC5D PCK1

7.53e-061856551bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY4 RELN NT5E TNXB CHRNA4

7.73e-0618665540070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

PCLO PAPPA FBXO17 USH1C PCK1

7.93e-06187655d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY4 RELN NT5E UNC5B TNXB

7.93e-0618765565d406122dffe18279f14a1ed35ba091730b97be
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY4 RELN NT5E UNC5B TNXB

7.93e-061876554c15c0ed41a55271fc793cb76fee97fa64190369
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY4 RELN NT5E UNC5B TNXB

7.93e-061876555274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC16A3 SYBU SEMA4A USH1C PCK1

8.14e-06188655d00f48afed62fc60d3530bb3b80ac0162b0b0ed8
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

ADCY4 RELN UNC5B BACE2 TNXB

8.14e-0618865580910dcbb51990f2baed240f319456c0d3fa2065
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADCY4 RELN NT5E BACE2 TNXB

8.14e-06188655aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PAPPA LRRK1 SLC45A1 TNXB COL1A2

8.57e-061906550fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCellwk_20-22-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADCY4 RELN UNC5B BACE2 TNXB

8.57e-06190655103e78c2233c3ee0c215a9dafe70705477e9ee5e
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXDC1 ENTPD2 ITGA8 TNXB COL1A2

8.79e-06191655b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLXDC1 TNC UNC5B ITGA8 COL1A2

8.79e-06191655107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLXDC1 TNC UNC5B ITGA8 COL1A2

8.79e-06191655bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ENTPD2 PAPPA BACE2 TNXB COL1A2

9.48e-06194655c9e589fe7df6a9b377654581a2aebb607cbb03b9
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC16A3 DAPK1 SEMA4A ITGAD ITGAX

9.72e-061956550ec1b572bbb92b6da3440139366a4c1743b1ad92
ToppCelldistal-Hematologic-Plasma-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NXPE4 ITGA8 SEMA4A TECTA GALR2

9.96e-061966558201aded3c7109fae5e6ca12bac2076acc7bf070
ToppCellwk_15-18-Endothelial-Lymph_endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADCY4 RELN UNC5B PCLO TNXB

9.96e-06196655ff627244d7f5fd6a2ec009dae32d3509f0e2d95e
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TNC ITGA8 PAPPA TNXB COL1A2

1.02e-05197655fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCelldistal-1-Hematologic-Plasma|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NXPE4 ITGA8 SEMA4A TECTA GALR2

1.02e-05197655f5499bfa9dbc111f12563b7006bc45c2423ad0cd
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNC PAPPA TNXB CHRNA4 COL1A2

1.02e-0519765516758f181ef07c60aee63072e1da9572c5c85414
ToppCell(2)_Fibroblasts-(23)_Fibro-4|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SLC16A3 NT5E GALR2 TNXB COL1A2

1.02e-05197655a183919023a4aca90a06be0e5e89c817b38c5574
ToppCell11.5-Airway-Mesenchymal-Mesenchyme_SERPINF1-high|Airway / Age, Tissue, Lineage and Cell class

TNC ENTPD2 PAPPA BACE2 COL1A2

1.02e-051976559a053a32ff9c3a85ef9a3382453acd619cc48546
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNC UNC5B ITGA8 FBXO17 COL1A2

1.05e-051986559d61483b0decac2fe90045b3474843360b2c49b3
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNC PAPPA TNXB UNC5D COL1A2

1.05e-051986557582ee9ec8a87ecb094201f1f9191b412f9d2875
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADCY4 RELN NT5E BACE2 TNXB

1.07e-051996551587d24b19f5bb64a3b6cc1df87c7c472cf41672
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADCY4 RELN NT5E BACE2 TNXB

1.07e-05199655a9c2041e54899cb8ccc026758647f3ae3ca457dd
ToppCellBiopsy_Other_PF-Endothelial-Lymphatic_Endothelial_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

ADCY4 RELN NT5E BACE2 TNXB

1.07e-05199655aa80c77fe4f6a141c780c7d8ecfff5d5a1c3b845
ToppCellBronchial-10x5prime-Endothelial-Endothelia_lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADCY4 RELN NT5E BACE2 TNXB

1.10e-05200655c59f262b2b0a7e7dcb2940d1e466f98db6c56625
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TNC ITGA8 PAPPA TNXB COL1A2

1.10e-052006556e3d1ae0ef84d3075afa40129a41169996462672
ToppCellBiopsy_Control_(H.)-Endothelial-Lymphatic_Endothelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

ADCY4 RELN NT5E BACE2 TNXB

1.10e-052006558cf218887ab030b7625610cb65b595170a17ebec
ToppCellBronchial-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADCY4 RELN NT5E BACE2 TNXB

1.10e-05200655e50ef394e3284a8323bfd60575b262b2be422aea
ToppCellfacs-Marrow-KLS-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F PKD1 ITGAX SLC38A6

8.19e-051576545d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NXPE4 LRRK1 ITGAD ITGAX

8.19e-05157654ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXDC1 PAPPA ITGAX TNXB

8.19e-051576547fdc0094dd5729990a91a30c1982a14c74650b52
ToppCellfacs-Marrow-KLS-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F PKD1 ITGAX SLC38A6

8.19e-05157654ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

TNC ITGA8 FBXO17 COL1A2

8.19e-05157654f147e24f2ece82e1c54750868954d09b3c461804
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXDC1 PAPPA ITGAX TNXB

8.19e-05157654c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXDC1 PAPPA ITGAX TNXB

8.19e-051576546b5b08bb5520fcf6f4c0560f7ed7645ec179806d
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4A FBXO17 ITGAD ITGAX

9.69e-051646547a51365bad2910c130bd952805f7a1bef51be481
ToppCelldroplet-Kidney-nan-24m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A3 NXPE4 ITGAD ITGAX

9.69e-05164654d57faa4fce1f1e9a92aaf5cb920af99323252e4b
ToppCelldroplet-Kidney-nan-24m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A3 NXPE4 ITGAD ITGAX

9.69e-05164654d0b6c29e61d15f4dbe4c1f6e5ed3e10f41f820ab
ToppCelldroplet-Kidney-nan-24m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A3 NXPE4 ITGAD ITGAX

9.69e-05164654718cc64b7ef7d03d095be4b2b54c449154da568c
ToppCellEndothelial-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

ADCY4 RELN NT5E TNXB

9.92e-05165654b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|356C / Donor, Lineage, Cell class and subclass (all cells)

ADCY4 RELN UNC5B TNXB

1.02e-041666545ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|356C / Donor, Lineage, Cell class and subclass (all cells)

ADCY4 RELN UNC5B TNXB

1.02e-041666546bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNC PAPPA ARF3 COL1A2

1.04e-04167654805129f887078340b260aa136b0ba19f2bd6ea03
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

ITGA8 PAPPA TNXB COL1A2

1.04e-04167654d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNC PAPPA ARF3 COL1A2

1.04e-0416765431cf8bf2eb523f6e7e319620648ff37fc09e2601
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNC PAPPA ARF3 COL1A2

1.04e-041676543acb18428d1d33ad430c2fd031b1a91baee3c01d
ToppCellAdult-Mesenchymal-chondrocyte-D175|Adult / Lineage, Cell type, age group and donor

NT5E PAPPA TNXB COL1A2

1.06e-0416865414071b961c9bdb54a8259b12a88237b802cbde36
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 NXPE4 DNAH2 DAPK1

1.06e-04168654e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN NT5E UNC5B TNXB

1.11e-041706546035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5B BACE2 CHRNA4 KPNA2

1.11e-04170654be2a34c70665d8d11332b1a70eda03d77cb7f7dd
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN NT5E UNC5B TNXB

1.11e-04170654c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCelldroplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNC GALR2 UNC5D COL1A2

1.11e-0417065410e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN NT5E UNC5B TNXB

1.11e-04170654dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

ADCY4 RELN BACE2 TNXB

1.19e-04173654dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAPPA BACE2 TNXB COL1A2

1.19e-0417365430d67738633493d47f06ae452424382f069b6c0a
ToppCelldroplet-Heart-nan-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAPK1 TNXB PCK1 COL1A2

1.22e-04174654cf4e0567f2a4ebe5534046b1c091af59b55bdc4f
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAPPA BACE2 TNXB COL1A2

1.22e-04174654a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellRSV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

MEGF8 HELZ2 RCBTB2 SLC45A1

1.24e-04175654ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCellRSV-Healthy-1|RSV / Virus stimulation, Condition and Cluster

MEGF8 HELZ2 RCBTB2 SLC45A1

1.24e-04175654ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RELN SLC16A3 UNC5B TNXB

1.24e-041756549a96a946db731ba24c9be34bedebf1f4a1372b9e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RELN SLC16A3 UNC5B TNXB

1.24e-0417565454c1f080195ad8392a095e83b56a4b54073d4c0d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RELN SLC16A3 UNC5B TNXB

1.24e-041756542b51406a2c2daa13ab4ed283ede038cd11d9e641
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ENTPD2 BACE2 TNXB COL1A2

1.27e-0417665408f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PLXDC1 PAPPA FBXO17 TNXB

1.27e-04176654bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

ITGA8 PAPPA TNXB COL1A2

1.27e-04176654510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH17 DAPK1 HYDIN UNC5D

1.27e-04176654327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PLXDC1 PAPPA FBXO17 TNXB

1.30e-041776543d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN NT5E UNC5B TNXB

1.30e-04177654227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH17 DAPK1 HYDIN UNC5D

1.30e-04177654da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN NT5E UNC5B TNXB

1.30e-0417765466ffa279147961080c104242a08b176e301d80e3
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN NT5E UNC5B TNXB

1.30e-041776540cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PCLO PAPPA USH1C PCK1

1.33e-0417865423a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TNC UNC5B PAPPA COL1A2

1.33e-041786548f31b3fac51591f7f2bcb898c07708b3e9f93a16
ToppCellPericytes-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

ENTPD2 ITGA8 FBXO17 COL1A2

1.33e-04178654a2448d868da2abe48c394c51264aad03e866dfec
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 SEMA4A HYDIN UNC5D

1.33e-04178654c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
DiseaseEhlers-Danlos syndrome (is_implicated_in)

TNXB COL1A2

1.70e-049652DOID:13359 (is_implicated_in)
Diseasetenascin measurement

TNC TNXB

2.13e-0410652EFO_0008296
Diseaseintracranial aneurysm (is_implicated_in)

PKD1 COL1A2

3.11e-0412652DOID:10941 (is_implicated_in)
Diseaset-tau:beta-amyloid 1-42 ratio measurement

UNC5B ITGA8 TOMM40

4.23e-0466653EFO_0007708
DiseaseNonsyndromic Deafness

TNC TECTA USH1C

7.70e-0481653C3711374
DiseaseLewy body dementia (is_marker_for)

IGF1R CHRNA4

7.98e-0419652DOID:12217 (is_marker_for)
Diseasep-tau:beta-amyloid 1-42 ratio measurement

UNC5B TOMM40

7.98e-0419652EFO_0007709
DiseaseAcute Confusional Senile Dementia

RELN IGF1R TOMM40

1.38e-0399653C0546126
DiseaseAlzheimer's Disease, Focal Onset

RELN IGF1R TOMM40

1.38e-0399653C0750900
DiseaseAlzheimer Disease, Early Onset

RELN IGF1R TOMM40

1.38e-0399653C0750901
DiseasePresenile dementia

RELN IGF1R TOMM40

1.38e-0399653C0011265
DiseaseAlzheimer Disease, Late Onset

RELN IGF1R TOMM40

1.38e-0399653C0494463
DiseaseInvolutional paraphrenia

RELN GALR2

1.39e-0325652C1571983
DiseasePsychosis, Involutional

RELN GALR2

1.39e-0325652C1571984
DiseaseInvolutional Depression

RELN GALR2

1.39e-0325652C0011574
DiseaseFamilial Alzheimer Disease (FAD)

RELN IGF1R TOMM40

1.42e-03100653C0276496
DiseaseAlzheimer's Disease

RELN IGF1R TOMM40

1.46e-03101653C0002395
DiseaseAlzheimer disease, polygenic risk score

SF3B3 TOMM40 SYBU LRBA ITGAX HYDIN

1.83e-03586656EFO_0030082, MONDO_0004975
DiseaseMajor Depressive Disorder

RELN PCLO TOMM40 GALR2

2.05e-03243654C1269683
Diseaselifestyle measurement, alcohol consumption measurement

LRBA BACE2 UNC5D

2.11e-03115653EFO_0007878, EFO_0010724
Diseaseosteoporosis (is_implicated_in)

IGF1R COL1A2

2.13e-0331652DOID:11476 (is_implicated_in)
Diseasemigraine disorder, glucose measurement

IGF1R SLC45A1

2.13e-0331652EFO_0004468, MONDO_0005277

Protein segments in the cluster

PeptideGeneStartEntry
TWQYVDQFVSESGGV

USH1C

181

Q9Y6N9
AEYIIQQGGWGTVFS

BCL2L13

191

Q9BXK5
AYLNGVGDFSVWEFS

DAPK1

801

P53355
SGEWVIVDAVGTYNT

CHRNA4

206

P43681
TVKYTQGSWTGFVGE

BACE2

146

Q9Y5Z0
VGWATSNYFVGAIQE

B4GALT4

26

O60513
GGVVSAWDQVSYFLF

ADCY4

111

Q8NFM4
VEYKNISFTVWDVGG

ARF3

56

P61204
VLTSDGEVFAWGYNN

RCBTB2

166

O95199
IFTNVAETSDGGVYW

PCK1

356

P35558
GFGDSVVQYANSWVV

ITGAX

36

P20702
YFQATWAVNNGIDTT

KCNH3

541

Q9ULD8
QEFGIGYSDTAWISS

SLC16A3

51

O15427
FSSQGQEYTVVFWDG

LRRK1

1541

Q38SD2
LFSVAQELSGQGWTY

KIFC1

441

Q9BW19
QELSGQGWTYSFVAS

KIFC1

446

Q9BW19
SGQEEGVFGWVTANY

ENTPD2

161

Q9Y5L3
DGVFTTYSDVWSFGV

IGF1R

1186

P08069
TDWFTSYVKNVVSGG

FBXO3

246

Q9UK99
QGWYTVQSDGVTQYI

PCLO

3371

Q9Y6V0
EYQLATGTWVSGAQS

MEGF8

1651

Q7Z7M0
NGELASYGEITWFVN

LRBA

321

P50851
GSVYQYWVITISGTE

PAPPA

916

Q13219
SFYWQGQVITASVAD

ITGA8

221

P53708
WVDFVQFYIQIGGES

RELN

1126

P78509
EAVWAVTNYTSGGTV

KPNA2

396

P52292
IVTVWNAGEDSYGTV

ITGAD

801

Q13349
VSFEQYGRDVSSWVG

FBXO17

246

Q96EF6
FQATIYTLDGWVFGS

GALR2

81

O43603
VWLGETINAGSQFEY

COL1A2

1226

P08123
GDVWPNSSAEITVYF

HYDIN

411

Q4G0P3
TLFWNGEGVFQYIQE

DNAH17

756

Q9UFH2
VEYKNISFTVWDVGG

ARF1

56

P84077
VQAASFGTFEQWVVF

HELZ2

241

Q9BYK8
WENFEATVQFGTVRG

DNAH2

151

Q9P225
DFWRSQVTGYSGSVT

SLC45A1

56

Q9Y2W3
VYEWTAGQQGSVSAE

D2HGDH

461

Q8N465
AYNSTGDFTVRVAGW

PKD1

1516

P98161
FGIFQAWAEATGAYV

IRF3

51

Q14653
WVGFGVTNRYTNVGS

MOXD2P

66

A6NHM9
FYGIFSSQWEGATIS

SEMA4F

326

O95754
GTYLVSFTLFWEGQV

NXPE4

161

Q6UWF7
QTETVYLFGGWDGTQ

MKLN1

281

Q9UL63
QWVDQSGVVKFYGSF

TAF2

521

Q6P1X5
YAVFTSQWQVGGTRS

SEMA4A

321

Q9H3S1
GSFNAERGWYVSVQQ

SLC38A6

6

Q8IZM9
TVAEVEDYGFAWQAG

SIPA1L3

986

O60292
LDAGDQYQGTIWFTV

NT5E

81

P21589
IVTWEEVTFYGGSST

TECTA

146

O75443
WSENVIGAAVSFPYV

TGFBRAP1

246

Q8WUH2
QYIVSGSDDGSFFIW

WDTC1

551

Q8N5D0
LYEQSVWITDVGSGF

NHLRC3

116

Q5JS37
TGSVDGFIEVWNFTT

SMU1

231

Q2TAY7
GYDQWATSQLIGTIF

SLC23A2

131

Q9UGH3
GGVVRQYWSSSFLVD

SYBU

596

Q9NX95
QGIVTFEDVAVYFSW

ZNF256

11

Q9Y2P7
WTVPEGQFDSFVVQY

TNXB

1796

P22105
WTTPDGTYDQFTIQV

TNC

1276

P24821
STTATVIVYVNGGWS

UNC5B

236

Q8IZJ1
TVVVYVNGGWSSWTE

UNC5D

246

Q6UXZ4
FSNTGEDWYVLVGVA

SF3B3

896

Q15393
QGADYGQISEETWTY

USP20

861

Q9Y2K6
VNWQVDGEYRGSDFT

TOMM40

186

O96008
TVVYFDNGTVFVVQW

PLXDC1

191

Q8IUK5
WVGVFLDYDNGSVSF

TRIM64C

406

A6NLI5
FDGTVQVYDATSWDG

WDR73

296

Q6P4I2
GLLGTYSFEWQSQVA

nan

36

Q8N9L7