Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	serine-type endopeptidase activity	KLK11 TPSAB1 OVCH2 PRSS56 PRSS33 KLK3 F7 PRSS46P PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	5.27e-12	190	140	15	GO:0004252
GeneOntologyMolecularFunction	serine-type peptidase activity	KLK11 TPSAB1 OVCH2 PRSS56 PRSS33 KLK3 F7 PRSS46P PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	1.81e-11	207	140	15	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	KLK11 TPSAB1 OVCH2 PRSS56 PRSS33 KLK3 F7 PRSS46P PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	2.54e-11	212	140	15	GO:0017171
GeneOntologyMolecularFunction	endopeptidase activity	KLK11 TPSAB1 OVCH2 PRSS56 CASP1 PRSS33 KLK3 F7 PRSS46P PRSS27 CAPN7 GZMK TMPRSS2 TPSG1 CTRL ESPL1 KLK2 TPSB2	1.33e-09	430	140	18	GO:0004175
GeneOntologyMolecularFunction	peptidase activity	KLK11 TPSAB1 OVCH2 PRSS56 CASP1 PRSS33 KLK3 F7 PRSS46P PRSS27 CAPN7 GZMK TMPRSS2 TPSG1 CTRL ESPL1 KLK2 TPSB2	7.65e-07	654	140	18	GO:0008233
GeneOntologyMolecularFunction	prolactin receptor binding	CSH1 CSH2 CSHL1	1.16e-05	7	140	3	GO:0005148
GeneOntologyMolecularFunction	growth hormone receptor binding	CSH1 CSH2 CSHL1	3.90e-05	10	140	3	GO:0005131
GeneOntologyMolecularFunction	hexose-phosphate:phosphate antiporter activity	SLC37A3 SLC37A2	2.90e-04	4	140	2	GO:0015526
GeneOntologyMolecularFunction	hexose phosphate transmembrane transporter activity	SLC37A3 SLC37A2	2.90e-04	4	140	2	GO:0015119
GeneOntologyMolecularFunction	glucose-6-phosphate transmembrane transporter activity	SLC37A3 SLC37A2	2.90e-04	4	140	2	GO:0015152
GeneOntologyMolecularFunction	glucose 6-phosphate:phosphate antiporter activity	SLC37A3 SLC37A2	2.90e-04	4	140	2	GO:0061513
GeneOntologyMolecularFunction	organophosphate:phosphate antiporter activity	SLC37A3 SLC37A2	1.00e-03	7	140	2	GO:0015315
GeneOntologyCellularComponent	growth hormone receptor complex	CSH1 CSH2 CSHL1	5.79e-06	6	140	3	GO:0070195
GeneOntologyCellularComponent	extracellular matrix	TPSAB1 HSPG2 SEMA7A CFP SSPOP F7 SVEP1 ITIH5 FBN2 FCGBP HMCN1 CSH1 CSH2 CSHL1 TPSB2	3.50e-05	656	140	15	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	TPSAB1 HSPG2 SEMA7A CFP SSPOP F7 SVEP1 ITIH5 FBN2 FCGBP HMCN1 CSH1 CSH2 CSHL1 TPSB2	3.63e-05	658	140	15	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	TPSAB1 HSPG2 SEMA7A CFP SSPOP F7 ITIH5 FBN2 HMCN1 CSH1 CSH2 CSHL1 TPSB2	5.90e-05	530	140	13	GO:0062023
MousePheno	decreased pituitary gland weight	CSH1 CSH2 CSHL1	2.51e-05	8	109	3	MP:0008938
MousePheno	absent somatotrophs	CSH1 CSH2 CSHL1	3.74e-05	9	109	3	MP:0008330
MousePheno	absent lactotrophs	CSH1 CSH2 CSHL1	3.74e-05	9	109	3	MP:0008333
MousePheno	disproportionate dwarf	HSPG2 CSH1 CSH2 CSHL1 PKD1	7.97e-05	57	109	5	MP:0002427
MousePheno	abnormal heart size	TMEM67 ACACB DISC1 GARS1 ATG2B KLK3 MMACHC TYRO3 FBN2 CSH1 CSH2 CSHL1 SLC6A20 PKD1 CDK5RAP1 TMPRSS2 ROBO1 HACL1 KLK2 RNF208 RIC1 ARHGAP33	9.60e-05	1180	109	22	MP:0005406
MousePheno	increased circulating ghrelin level	CSH1 CSH2 CSHL1	9.64e-05	12	109	3	MP:0011612
MousePheno	abnormal pituitary gland weight	CSH1 CSH2 CSHL1	9.64e-05	12	109	3	MP:0008937
Domain	TRYPSIN_HIS	KLK11 TPSAB1 OVCH2 PRSS56 PRSS33 KLK3 F7 PRSS46P PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	2.08e-15	107	138	15	PS00134
Domain	Peptidase_S1A	KLK11 TPSAB1 OVCH2 PRSS56 PRSS33 KLK3 F7 PRSS46P PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	4.81e-15	113	138	15	IPR001314
Domain	TRYPSIN_DOM	KLK11 TPSAB1 OVCH2 PRSS56 PRSS33 KLK3 F7 PRSS46P PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	6.29e-15	115	138	15	PS50240
Domain	Tryp_SPc	KLK11 TPSAB1 OVCH2 PRSS56 PRSS33 KLK3 F7 PRSS46P PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	8.18e-15	117	138	15	SM00020
Domain	Trypsin_dom	KLK11 TPSAB1 OVCH2 PRSS56 PRSS33 KLK3 F7 PRSS46P PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	1.36e-14	121	138	15	IPR001254
Domain	Trypsin	KLK11 TPSAB1 OVCH2 PRSS56 PRSS33 KLK3 F7 PRSS46P PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	1.36e-14	121	138	15	PF00089
Domain	Peptidase_S1_PA	KLK11 TPSAB1 OVCH2 PRSS56 PRSS33 KLK3 F7 PRSS46P PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	1.75e-14	123	138	15	IPR009003
Domain	TRYPSIN_HIS	KLK11 TPSAB1 PRSS56 PRSS33 KLK3 F7 PRSS46P PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	2.90e-14	103	138	14	IPR018114
Domain	TRYPSIN_SER	KLK11 TPSAB1 OVCH2 PRSS56 PRSS33 KLK3 F7 PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	4.38e-14	106	138	14	PS00135
Domain	TRYPSIN_SER	KLK11 TPSAB1 PRSS56 PRSS33 KLK3 F7 PRSS27 GZMK TMPRSS2 CTRL KLK2 TPSB2	2.73e-12	90	138	12	IPR033116
Domain	SOMATOTROPIN_2	CSH1 CSH2 CSHL1	7.77e-06	6	138	3	PS00338
Domain	SOMATOTROPIN_1	CSH1 CSH2 CSHL1	7.77e-06	6	138	3	PS00266
Domain	Hormone_1	CSH1 CSH2 CSHL1	7.77e-06	6	138	3	PF00103
Domain	Somatotropin	CSH1 CSH2 CSHL1	1.35e-05	7	138	3	IPR001400
Domain	IGv	HSPG2 OBSCN DSCAML1 HMCN1 PIGR ROBO1	1.93e-05	75	138	6	SM00406
Domain	LDLRA_1	HSPG2 SSPOP MALRD1 PKD1 TMPRSS2	2.72e-05	48	138	5	PS01209
Domain	LDLRA_2	HSPG2 SSPOP MALRD1 PKD1 TMPRSS2	3.01e-05	49	138	5	PS50068
Domain	-	SEMA3F SEMA7A GNB1L WDR54 THOC3 ARHGEF10L PLAA TECPR2 WRAP73 WDR17 RIC1	3.77e-05	333	138	11	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	SEMA3F SEMA7A GNB1L WDR54 THOC3 ARHGEF10L PLAA TECPR2 WRAP73 WDR17 RIC1	3.98e-05	335	138	11	IPR015943
Domain	EGF	SELE HSPG2 F7 SVEP1 FBN2 FCGBP MALRD1 HMCN1 ADGRE1	6.37e-05	235	138	9	SM00181
Domain	EGF_3	SELE HSPG2 SSPOP F7 SVEP1 FBN2 MALRD1 HMCN1 ADGRE1	6.37e-05	235	138	9	PS50026
Domain	C8	MUC19 SSPOP FCGBP	8.27e-05	12	138	3	PF08742
Domain	TIL	MUC19 SSPOP FCGBP	8.27e-05	12	138	3	PF01826
Domain	ig	SEMA3F HSPG2 LILRA1 OBSCN DSCAML1 TYRO3 HMCN1 PIGR	8.51e-05	190	138	8	PF00047
Domain	Immunoglobulin	SEMA3F HSPG2 LILRA1 OBSCN DSCAML1 TYRO3 HMCN1 PIGR	8.51e-05	190	138	8	IPR013151
Domain	EGF-like_dom	SELE HSPG2 F7 SVEP1 FBN2 FCGBP MALRD1 HMCN1 ADGRE1	9.91e-05	249	138	9	IPR000742
Domain	Unchr_dom_Cys-rich	MUC19 SSPOP FCGBP	1.07e-04	13	138	3	IPR014853
Domain	C8	MUC19 SSPOP FCGBP	1.07e-04	13	138	3	SM00832
Domain	EGF_1	SELE HSPG2 SSPOP F7 SVEP1 FBN2 MALRD1 HMCN1 ADGRE1	1.19e-04	255	138	9	PS00022
Domain	TIL_dom	MUC19 SSPOP FCGBP	1.35e-04	14	138	3	IPR002919
Domain	EGF_2	SELE HSPG2 SSPOP F7 SVEP1 FBN2 MALRD1 HMCN1 ADGRE1	1.59e-04	265	138	9	PS01186
Domain	Growth_fac_rcpt_	TMEM67 HSPG2 SVEP1 FBN2 IGFBP1 HMCN1 ADGRE1	1.61e-04	156	138	7	IPR009030
Domain	VWF_type-D	MUC19 SSPOP FCGBP	2.06e-04	16	138	3	IPR001846
Domain	VWFD	MUC19 SSPOP FCGBP	2.06e-04	16	138	3	PS51233
Domain	VWD	MUC19 SSPOP FCGBP	2.06e-04	16	138	3	SM00216
Domain	VWD	MUC19 SSPOP FCGBP	2.06e-04	16	138	3	PF00094
Domain	LDLR_class-A_CS	HSPG2 SSPOP MALRD1 TMPRSS2	2.12e-04	40	138	4	IPR023415
Domain	-	SVEP1 ITIH5 INTS14 MDN1 HMCN1	2.19e-04	74	138	5	3.40.50.410
Domain	EGF_CA	HSPG2 F7 SVEP1 FBN2 HMCN1 ADGRE1	2.92e-04	122	138	6	SM00179
Domain	EGF-like_Ca-bd_dom	HSPG2 F7 SVEP1 FBN2 HMCN1 ADGRE1	3.19e-04	124	138	6	IPR001881
Domain	Sugar_P_transporter	SLC37A3 SLC37A2	3.22e-04	4	138	2	IPR000849
Domain	EGF	SELE HSPG2 F7 SVEP1 MALRD1 HMCN1	3.48e-04	126	138	6	PF00008
Domain	VWC_out	MUC19 SSPOP FCGBP	3.51e-04	19	138	3	SM00215
Domain	VWFA	SVEP1 ITIH5 INTS14 MDN1 HMCN1	3.54e-04	82	138	5	PS50234
Domain	IGc2	SEMA3F HSPG2 LILRA1 OBSCN DSCAML1 TYRO3 HMCN1 ROBO1	3.64e-04	235	138	8	SM00408
Domain	Ig_sub2	SEMA3F HSPG2 LILRA1 OBSCN DSCAML1 TYRO3 HMCN1 ROBO1	3.64e-04	235	138	8	IPR003598
Domain	-	HSPG2 SSPOP MALRD1 TMPRSS2	3.66e-04	46	138	4	4.10.400.10
Domain	VWA	SVEP1 ITIH5 INTS14 MDN1 HMCN1	3.96e-04	84	138	5	SM00327
Domain	Apc4_WD40_dom	THOC3 WRAP73 WDR17	4.10e-04	20	138	3	IPR024977
Domain	ANAPC4_WD40	THOC3 WRAP73 WDR17	4.10e-04	20	138	3	PF12894
Domain	LDrepeatLR_classA_rpt	HSPG2 SSPOP MALRD1 TMPRSS2	4.67e-04	49	138	4	IPR002172
Domain	LDLa	HSPG2 SSPOP MALRD1 TMPRSS2	4.67e-04	49	138	4	SM00192
Domain	WSC	KREMEN2 PKD1	5.34e-04	5	138	2	SM00321
Domain	WSC	KREMEN2 PKD1	5.34e-04	5	138	2	PS51212
Domain	WSC_carb-bd	KREMEN2 PKD1	5.34e-04	5	138	2	IPR002889
Domain	WSC	KREMEN2 PKD1	5.34e-04	5	138	2	PF01822
Domain	Somatotropin_CS	CSH1 CSHL1	5.34e-04	5	138	2	IPR018116
Domain	Sushi	SELE CSMD2 CR1 SVEP1	5.87e-04	52	138	4	PF00084
Domain	CCP	SELE CSMD2 CR1 SVEP1	6.78e-04	54	138	4	SM00032
Domain	EGF-like_CS	SELE HSPG2 F7 SVEP1 FBN2 MALRD1 HMCN1 ADGRE1	7.26e-04	261	138	8	IPR013032
Domain	EGF_Ca-bd_CS	F7 SVEP1 FBN2 HMCN1 ADGRE1	7.66e-04	97	138	5	IPR018097
Domain	SUSHI	SELE CSMD2 CR1 SVEP1	7.78e-04	56	138	4	PS50923
Domain	Sushi_SCR_CCP_dom	SELE CSMD2 CR1 SVEP1	8.32e-04	57	138	4	IPR000436
Domain	EGF_CA	F7 SVEP1 FBN2 HMCN1 ADGRE1	8.40e-04	99	138	5	PS01187
Domain	VWF_A	SVEP1 ITIH5 INTS14 MDN1 HMCN1	8.40e-04	99	138	5	IPR002035
Domain	ASX_HYDROXYL	F7 SVEP1 FBN2 HMCN1 ADGRE1	8.79e-04	100	138	5	PS00010
Domain	cEGF	FBN2 HMCN1 ADGRE1	9.06e-04	26	138	3	PF12662
Domain	cEGF	FBN2 HMCN1 ADGRE1	9.06e-04	26	138	3	IPR026823
Domain	IG_LIKE	SEMA3F HSPG2 LILRA1 SEMA7A OBSCN DSCAML1 TYRO3 CD1D HMCN1 PIGR ROBO1	1.06e-03	491	138	11	PS50835
Domain	WD_REPEATS_1	GNB1L WDR54 THOC3 PLAA TECPR2 WRAP73 WDR17 RIC1	1.09e-03	278	138	8	PS00678
Domain	WD_REPEATS_2	GNB1L WDR54 THOC3 PLAA TECPR2 WRAP73 WDR17 RIC1	1.12e-03	279	138	8	PS50082
Domain	WD_REPEATS_REGION	GNB1L WDR54 THOC3 PLAA TECPR2 WRAP73 WDR17 RIC1	1.12e-03	279	138	8	PS50294
Domain	EGF-type_Asp/Asn_hydroxyl_site	F7 SVEP1 FBN2 HMCN1 ADGRE1	1.14e-03	106	138	5	IPR000152
Domain	IG	SEMA3F HSPG2 LILRA1 SEMA7A OBSCN DSCAML1 TYRO3 HMCN1 PIGR ROBO1	1.16e-03	421	138	10	SM00409
Domain	Ig_sub	SEMA3F HSPG2 LILRA1 SEMA7A OBSCN DSCAML1 TYRO3 HMCN1 PIGR ROBO1	1.16e-03	421	138	10	IPR003599
Domain	Ig-like_dom	SEMA3F HSPG2 LILRA1 SEMA7A OBSCN DSCAML1 TYRO3 CD1D HMCN1 PIGR ROBO1	1.29e-03	503	138	11	IPR007110
Domain	WD40_repeat_dom	GNB1L WDR54 THOC3 ARHGEF10L PLAA TECPR2 WDR17 RIC1	1.66e-03	297	138	8	IPR017986
Domain	4_helix_cytokine-like_core	DISC1 CSH1 CSH2 CSHL1	2.20e-03	74	138	4	IPR009079
Domain	VWC	MUC19 SSPOP FCGBP	2.76e-03	38	138	3	SM00214
Domain	GFP-like	SVEP1 HMCN1	2.85e-03	11	138	2	IPR023413
Domain	-	SVEP1 HMCN1	2.85e-03	11	138	2	2.40.155.10
Domain	Ig_I-set	HSPG2 OBSCN DSCAML1 TYRO3 HMCN1 ROBO1	2.90e-03	190	138	6	IPR013098
Domain	I-set	HSPG2 OBSCN DSCAML1 TYRO3 HMCN1 ROBO1	2.90e-03	190	138	6	PF07679
Domain	Ig_V-set	HSPG2 OBSCN DSCAML1 HMCN1 PIGR ROBO1	3.65e-03	199	138	6	IPR013106
Domain	VWF_dom	MUC19 SSPOP FCGBP	3.67e-03	42	138	3	IPR001007
Domain	-	SEMA3F HSPG2 LILRA1 SEMA7A OBSCN FSD1 DSCAML1 TYRO3 CD1D HMCN1 PIGR ROBO1	3.77e-03	663	138	12	2.60.40.10
Domain	EGF_CA	SVEP1 FBN2 HMCN1 ADGRE1	3.79e-03	86	138	4	PF07645
Domain	WD40	GNB1L WDR54 THOC3 PLAA TECPR2 WRAP73 WDR17	3.81e-03	268	138	7	SM00320
Domain	THDP-binding	OGDH HACL1	4.01e-03	13	138	2	IPR029061
Domain	-	OGDH HACL1	4.01e-03	13	138	2	3.40.50.970
Domain	WD40_repeat	GNB1L WDR54 THOC3 PLAA TECPR2 WRAP73 WDR17	4.13e-03	272	138	7	IPR001680
Domain	Ldl_recept_a	HSPG2 SSPOP MALRD1	4.46e-03	45	138	3	PF00057
Domain	6-blade_b-propeller_TolB-like	NHLRC1 TECPR2 WRAP73	4.75e-03	46	138	3	IPR011042
Domain	CUB	OVCH2 KREMEN2 CSMD2	5.67e-03	49	138	3	PF00431
Domain	CUB	OVCH2 KREMEN2 CSMD2	6.00e-03	50	138	3	SM00042
Domain	Ig-like_fold	SEMA3F HSPG2 LILRA1 SEMA7A OBSCN FSD1 DSCAML1 TYRO3 CD1D HMCN1 PIGR ROBO1	6.16e-03	706	138	12	IPR013783
Domain	4_helix_cytokine_core	CSH1 CSH2 CSHL1	6.34e-03	51	138	3	IPR012351
Domain	CUB	OVCH2 KREMEN2 CSMD2	7.06e-03	53	138	3	PS01180
Domain	fn3	OBSCN FSD1 DSCAML1 TYRO3 ROBO1	7.10e-03	162	138	5	PF00041
Pubmed	Administration of human insulin-like growth factor-binding protein-1 increases circulating levels of growth hormone in mice.	IGFBP1 CSH1 CSH2 CSHL1	3.86e-09	6	141	4	15166120
Pubmed	Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns.	TPSAB1 PRSS33 PRSS27 TPSG1	5.33e-08	10	141	4	14583634
Pubmed	The human growth hormone gene locus: structure, evolution, and allelic variations.	CSH1 CSH2 CSHL1	6.52e-08	3	141	3	3030680
Pubmed	Developmental control and alternative splicing of the placentally expressed transcripts from the human growth hormone gene cluster.	CSH1 CSH2 CSHL1	2.60e-07	4	141	3	1378436
Pubmed	Hoxa5 overexpression correlates with IGFBP1 upregulation and postnatal dwarfism: evidence for an interaction between Hoxa5 and Forkhead box transcription factors.	IGFBP1 CSH1 CSH2 CSHL1	3.41e-07	15	141	4	12163409
Pubmed	FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice.	FBN2 IGFBP1 CSH1 CSH2 CSHL1	4.60e-07	38	141	5	26134413
Pubmed	Central growth hormone action regulates metabolism during pregnancy.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	31479305
Pubmed	Molecular evolution of growth hormone and receptor in the guinea-pig, a mammal unresponsive to growth hormone.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	10767558
Pubmed	Rescue of pituitary function in a mouse model of isolated growth hormone deficiency type II by RNA interference.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	18006625
Pubmed	Growth hormone prevents the development of autoimmune diabetes.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	24218587
Pubmed	Body composition of inactivated growth hormone (oMt1a-oGH) transgenic mice: generation of an obese phenotype.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	9546108
Pubmed	Transgene transmission to progeny by oMt1a-oGH transgenic mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	16201410
Pubmed	Genes that prolong life: relationships of growth hormone and growth to aging and life span.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	11487592
Pubmed	Overexpressed growth hormone (GH) synergistically promotes carcinogen-initiated liver tumour growth by promoting cellular proliferation in emerging hepatocellular neoplasms in female and male GH-transgenic mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	11318985
Pubmed	Identification of the glomerular podocyte as a target for growth hormone action.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	17272398
Pubmed	Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	20707609
Pubmed	Induction of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	1874564
Pubmed	Growth Hormone Deficiency and Excess Alter the Gut Microbiome in Adult Male Mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	32100023
Pubmed	Transgenic mice expressing bovine GH develop arthritic disorder and self-antibodies.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	10810296
Pubmed	Somatotropin transgenic mice have reduced jejunal active glucose transport rates.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	7965203
Pubmed	Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	17347312
Pubmed	Pleiotropic effects of growth hormone signaling in aging.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	21852148
Pubmed	Body composition, bone mass and microstructural analysis in GH-transgenic mice reveals that skeletal changes are specific to bone compartment and gender.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	12175649
Pubmed	Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	15070902
Pubmed	A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	14726450
Pubmed	UV photodegradation of murine growth hormone: chemical analysis and immunogenicity consequences.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	24758742
Pubmed	Consequences of overexpression of growth hormone in transgenic mice on liver cytochrome P450 enzymes.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	10076541
Pubmed	Overgrowth of skin in growth hormone transgenic mice depends on the presence of male gonads.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	10594738
Pubmed	Hypoxia and cytoplasmic alkalinization upregulate growth hormone expression in lymphocytes.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	23639351
Pubmed	Pituitary growth hormone network responses are sexually dimorphic and regulated by gonadal steroids in adulthood.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	21098290
Pubmed	Age-related changes in body composition of bovine growth hormone transgenic mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	18948397
Pubmed	Heterogeneous growth hormone (GH) gene mutations in familial GH deficiency.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	8496314
Pubmed	Exploring endocrine GH pattern in mice using rank plot analysis and random blood samples.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	21045135
Pubmed	Analysis of gender difference of cardiac risk biomarkers using hGH-transgenic mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	16508206
Pubmed	Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	15616010
Pubmed	Nitric oxide stimulates embryonic somatotroph differentiation and growth hormone mRNA and protein expression through a cyclic guanosine monophosphate-independent mechanism.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	19019400
Pubmed	The Effects of 20-kDa Human Placental GH in Male and Female GH-deficient Mice: An Improved Human GH?	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	32556100
Pubmed	High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	1525063
Pubmed	Obesity and elevated plasma leptin concentration in oMT1A-o growth hormone transgenic mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	11346667
Pubmed	Cardiac contractile function is enhanced in isolated ventricular myocytes from growth hormone transgenic mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	12010633
Pubmed	Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	17626886
Pubmed	Regulation of rapid signal transducer and activator of transcription-5 phosphorylation in the resting cells of the growth plate and in the liver by growth hormone and feeding.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	19359380
Pubmed	Growth hormone stimulates the selective trafficking of thymic CD4+CD8- emigrants to peripheral lymphoid organs.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	15316240
Pubmed	Involvement of insulin-like growth factor-1 in the effect of caloric restriction: regulation of plasma adiponectin and leptin.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	17301034
Pubmed	Growth hormone action in the developing neural retina: a proteomic analysis.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	18203262
Pubmed	Assignment of the porcine growth hormone gene to chromosome 12.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	2249485
Pubmed	Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPARgamma pathway.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	17242167
Pubmed	A single injection of double-stranded adeno-associated viral vector expressing GH normalizes growth in GH-deficient mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	18180319
Pubmed	Cloning and characterisation of the GH gene from the common dolphin (Delphinus delphis).	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	12225773
Pubmed	Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families.	TPSAB1 TPSG1 TPSB2	6.48e-07	5	141	3	10843716
Pubmed	The related genes encoding growth hormone and prolactin have been dispersed to chromosomes 10 and 17 in the rat.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	3780533
Pubmed	High, persistent hepatocellular proliferation and apoptosis precede hepatocarcinogenesis in growth hormone transgenic mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	10395045
Pubmed	Effect of genetic background on growth of mice hemizygous for wild-type or dwarf mutated bovine growth hormone transgenes.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	24190208
Pubmed	Brief report: short stature caused by a mutant growth hormone.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	8552145
Pubmed	Promotion of Joint Degeneration and Chondrocyte Metabolic Dysfunction by Excessive Growth Hormone in Mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	36762426
Pubmed	High molecular weight isoforms of growth hormone in cells of the immune system.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	21741628
Pubmed	Structure of the growth hormone-encoding gene and its promoter in mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	8647448
Pubmed	Thiol-Disulfide Exchange in Human Growth Hormone.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	26887678
Pubmed	The role of growth hormone in fetal mouse reproductive tract differentiation.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	8756530
Pubmed	GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	31099824
Pubmed	Hot spots for growth hormone gene deletions in homologous regions outside of Alu repeats.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	1980158
Pubmed	Vitamin D3 cannot revert desensitization of growth hormone (GH)-induced STAT5-signaling in GH-overexpressing mice non-calcemic tissues.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	17881271
Pubmed	Neural growth hormone implicated in body weight sex differences.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	23861378
Pubmed	Growth hormone increases low-density lipoprotein receptor and HMG-CoA reductase mRNA expression in mesangial cells.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	12759574
Pubmed	Growth hormone production and action in N1E-115 neuroblastoma cells.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	19301152
Pubmed	Adipocyte insensitivity to insulin in growth hormone-transgenic mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	11350075
Pubmed	Transgenic mice overexpressing growth hormone (GH) have reduced or increased cardiac apoptosis through activation of multiple GH-dependent or -independent cell death pathways.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	18617616
Pubmed	Growth hormone and fertility in oMt1a-oGH transgenic mice.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	11570960
Pubmed	Promoter shuffling has occurred during the evolution of the vertebrate growth hormone gene.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	10974531
Pubmed	Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	23428905
Pubmed	Cardiac expression of adenine nucleotide translocase-1 in transgenic mice overexpressing bovine GH.	CSH1 CSH2 CSHL1	6.48e-07	5	141	3	17761891
Pubmed	Growth hormone, acting in part through the insulin-like growth factor axis, rescues developmental, but not metabolic, activity in the mammary gland of mice expressing a single allele of the prolactin receptor.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	12399427
Pubmed	GH modulates hepatic epidermal growth factor signaling in the mouse.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	20032199
Pubmed	Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	11316754
Pubmed	The rise in growth hormone during starvation does not serve to maintain glucose levels or lean mass but is required for appropriate adipose tissue response in female mice.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	23150490
Pubmed	Nucleotide sequence of mouse prolactin and growth hormone mRNAs and expression of these mRNAs during pregnancy.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	2991252
Pubmed	Third party data gene data set of eutherian growth hormone genes.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	26697363
Pubmed	Effects of long-term treatment with growth hormone-releasing peptide-2 in the GHRH knockout mouse.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	15985453
Pubmed	Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	20863500
Pubmed	Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	12208853
Pubmed	Involvement of growth hormone as a regulating factor in sex differences of mouse hepatic aldehyde oxidase.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	9175714
Pubmed	Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the C3(1)/T antigen mouse.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	16141391
Pubmed	Sex differences in thrombosis in mice are mediated by sex-specific growth hormone secretion patterns.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	18618017
Pubmed	Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	14759511
Pubmed	Osteocalcin induces growth hormone/insulin-like growth factor-1 system by promoting testosterone synthesis in male mice.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	24691732
Pubmed	CTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	38951485
Pubmed	Evidence that growth hormone exerts a feedback effect on stomach ghrelin production and secretion.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	14530511
Pubmed	Growth hormone induces hepatic production of fibroblast growth factor 21 through a mechanism dependent on lipolysis in adipocytes.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	21849508
Pubmed	Stimulation of endogenous pulsatile growth hormone secretion by activation of growth hormone secretagogue receptor reduces the fat accumulation and improves the insulin sensitivity in obese mice.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	33368660
Pubmed	Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	14702113
Pubmed	Systemic over-secretion of growth hormone in transgenic mice results in a specific pattern of skeletal modeling and adaptation.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	9556071
Pubmed	Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	8990189
Pubmed	Evidence that sensitivity to growth hormone (GH) is growth period and tissue type dependent: studies in GH-deficient lit/lit mice.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	12933669
Pubmed	Insulin-like growth factor 1 mediates negative feedback to somatotroph GH expression via POU1F1/CREB binding protein interactions.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	22890843
Pubmed	Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	15138153
Pubmed	Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against Streptococcus pneumoniae.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	30333823
Pubmed	GH/STAT5 signaling during the growth period in livers of mice overexpressing GH.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	25691498
Pubmed	The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	23349524
Pubmed	Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	26762506
Pubmed	Loss of fibroblast growth factor 21 action induces insulin resistance, pancreatic islet hyperplasia and dysfunction in mice.	CSH1 CSH2 CSHL1	1.29e-06	6	141	3	25811804
Interaction	CSH1 interactions	CSH1 CSH2 CSHL1 PADI2	5.64e-06	18	136	4	int:CSH1
Interaction	CSHL1 interactions	CSH1 CSH2 CSHL1	1.03e-05	7	136	3	int:CSHL1
Cytoband	16p13.3	TPSAB1 KREMEN2 ZNF205 PRSS33 PRSS27 PKD1 TPSG1 TPSB2	9.78e-07	244	141	8	16p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr16p13	TPSAB1 KREMEN2 ZNF205 PRSS33 PRSS27 PKD1 TPSG1 TPSB2	5.56e-05	426	141	8	chr16p13
Cytoband	17q24.2	CSH1 CSH2 CSHL1	1.08e-04	30	141	3	17q24.2
Cytoband	Ensembl 112 genes in cytogenetic band chr3p21	SEMA3F ABHD14A MAP4 GRM2 PRSS46P SLC6A20	4.56e-04	316	141	6	chr3p21
GeneFamily	Proteases, serine	KLK11 PRSS56 PRSS33 PRSS46P PRSS27 TMPRSS2 TPSG1	4.45e-08	63	97	7	738
GeneFamily	Growth hormone family	CSH1 CSH2 CSHL1	2.96e-06	6	97	3	1175
GeneFamily	Kallikreins	KLK11 KLK3 KLK2	7.97e-05	16	97	3	616
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 OBSCN DSCAML1 TYRO3 HMCN1 ROBO1	2.30e-04	161	97	6	593
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELE CSMD2 CR1 SVEP1	2.47e-04	57	97	4	1179
GeneFamily	Solute carriers	SLC29A3 SLC22A25 SLC37A3 SLC35G6 SLC40A1 SLC47A2 SLC6A20 SLC6A5 SLC37A2	2.72e-04	395	97	9	752
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	SEMA7A CR1 ACKR1	1.02e-03	37	97	3	454
GeneFamily	Fibronectin type III domain containing	OBSCN FSD1 DSCAML1 TYRO3 ROBO1	1.71e-03	160	97	5	555
GeneFamily	WD repeat domain containing	GNB1L WDR54 THOC3 PLAA WRAP73 WDR17	2.88e-03	262	97	6	362
GeneFamily	Immunoglobulin like domain containing	SEMA3F HSPG2 SEMA7A DSCAML1 TYRO3	3.84e-03	193	97	5	594
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA3F SEMA7A	5.08e-03	20	97	2	736
Coexpression	NIKOLSKY_BREAST_CANCER_16P13_AMPLICON	TPSAB1 KREMEN2 ZNF205 PRSS33 PRSS27 PKD1 TPSG1 TPSB2	2.72e-07	119	141	8	M1788
Coexpression	MARTENS_TRETINOIN_RESPONSE_UP	NHLRC1 GPR6 OR6S1 CDH23 PRSS33 FSD1 GRM2 KLK3 F7 ARHGEF10L PRSS46P NLRP6 CSHL1 SLC6A20 TMPRSS2 TPSG1 ACKR1 KLK2	8.29e-07	855	141	18	M2098
ToppCell	Basal_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	KLK11 OVCH2 SLC47A2 IRF9 HMCN1 SMO ALDH1A3	7.34e-07	158	141	7	51e3ed1b91b010404d66e3e7efdbffc0c815e25b
ToppCell	Monocytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	LILRA1 CASP1 CDH23 CFP KLK3 CD1D PADI2	1.20e-06	170	141	7	4e93b66b3033e6e4d5f6d2f41974623a53108f5e
ToppCell	mild-Myeloid-Eosinophils\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TPSAB1 ACACB SEMA7A PRSS33 TEX101 ADGRE1 TPSB2	1.25e-06	171	141	7	5c8198182495bda7a826e9d80aa467f4eb1094ec
ToppCell	10x5'-bone_marrow-Mast-Mast_cell_lympho\|bone_marrow / Manually curated celltypes from each tissue	HSPG2 FOXRED1 ABCA2 SEMA7A HAL CTRL TPSB2	1.82e-06	181	141	7	56fa77ae31f3b7de6e441a439c33a11353b6573a
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN SSPOP DSCAML1 FBN2 HMCN1 TRPM3 ROBO1	2.03e-06	184	141	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN SSPOP DSCAML1 FBN2 HMCN1 TRPM3 ROBO1	2.03e-06	184	141	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN SSPOP DSCAML1 FBN2 HMCN1 TRPM3 ROBO1	2.03e-06	184	141	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	SELE SVEP1 ITIH5 TYRO3 HMCN1 ROBO1 ACKR1	2.26e-06	187	141	7	e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCell	10x5'-Lung-Myeloid_Monocytic\|Lung / Manually curated celltypes from each tissue	LILRA1 CASP1 CDH23 CFP CR1 CD1D ADGRE1	2.79e-06	193	141	7	ebe6be10ef5de9e1da988e263106698d3db42fce
ToppCell	distal-Hematologic-Nonclassical_Monocyte-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRA1 KREMEN2 CASP1 CDH23 CFP HAL ADGRE1	2.89e-06	194	141	7	f1cabb198ab32deaf299899c5e8f42d861b8c574
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LILRA1 CASP1 CDH23 CFP CR1 CD1D ADGRE1	2.99e-06	195	141	7	01da7115e38c280fb0baff2032b62bdb609bad5e
ToppCell	control-unassigned\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZNF609 SLC37A3 ACACB MMACHC PCED1B CCDC157 ARHGAP33	3.41e-06	199	141	7	5db7c8089172ac8e796613b3cef618d87007a0ab
ToppCell	Control_saline-Hematopoietic_Myeloid-Dendritic_cells-pDC\|Control_saline / Treatment groups by lineage, cell group, cell type	FOXRED1 TTC24 SEMA7A CDH23 CFP CR1 LPAR2	3.41e-06	199	141	7	34b95e27581bb127e0b921e9c068dc094cb86b37
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Monocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LILRA1 DISC1 CDH23 CFP CR1 CD1D ADGRE1	3.53e-06	200	141	7	fd72fe6565e2f4885481991492d58c323ab1ad40
ToppCell	Control_saline-Hematopoietic_Myeloid-Dendritic_cells\|Control_saline / Treatment groups by lineage, cell group, cell type	FOXRED1 TTC24 SEMA7A CDH23 CFP CR1 LPAR2	3.53e-06	200	141	7	1559844b3116d41a69081e4ee89e64744a760181
ToppCell	Serous\|World / shred by cell class for turbinate	PRSS33 KLK3 FCGBP PIGR TEX101 PADI2	8.40e-06	150	141	6	6a326662d58b0f17d6efa8cc28571f4cbbf57c2d
ToppCell	severe_COVID-19-MAIT\|World / disease group, cell group and cell class (v2)	ABCA2 TTC24 OBSCN FSD1 F7 GZMK	9.77e-06	154	141	6	65ec7f7ef05c589903c4c9fe3849478c325fdc61
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CDH23 CFP SEPHS1 MALRD1 SLC37A2 LRRC7	1.01e-05	155	141	6	4559e3011514041b65c17ae4ede29da202bce14c
ToppCell	10x5'-bone_marrow-Mast\|bone_marrow / Manually curated celltypes from each tissue	TPSAB1 HSPG2 TEX101 HAL TPSG1 TPSB2	1.17e-05	159	141	6	c3d3570e83c5d25cc92fa3a7a8f0dc2f89a72913
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC19 DSCAML1 SVEP1 FBN2 HMCN1 WDR17	1.21e-05	160	141	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SLC37A3 KLK3 SLC40A1 ADGRE1 PADI2 RGL4	1.21e-05	160	141	6	bb1bb3673059768c0ea0160d29fff127f3a4ecb4
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLC37A3 KLK3 SLC40A1 ADGRE1 PADI2 RGL4	1.21e-05	160	141	6	76f49b8b4450fa8acd36326bfa36a5d1f4bd95fb
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC19 DSCAML1 SVEP1 FBN2 HMCN1 WDR17	1.21e-05	160	141	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	10x5'-bone_marrow-Mast-Mast_cells\|bone_marrow / Manually curated celltypes from each tissue	TPSAB1 HSPG2 TEX101 HAL TPSG1 TPSB2	1.26e-05	161	141	6	15ba7e69699558353cfeecdcf1dbc2e147379ed6
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F7 NLRP6 IGFBP1 PIGR HACL1 HAL	1.40e-05	164	141	6	90afae3cca108ebfb44ff2ec4adcbb8c68a0bdf2
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	LILRA1 CR1 SVEP1 CD1D HMCN1 ALDH1A3	1.55e-05	167	141	6	d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCell	3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPSAB1 SEMA7A TPSG1 PADI2 TPSB2 RIC1	1.83e-05	172	141	6	13d7117f92a92d77d6b4335ed800c585dc8b4511
ToppCell	3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPSAB1 SEMA7A TPSG1 PADI2 TPSB2 RIC1	1.83e-05	172	141	6	3d83b2f03ad3af4dae3fe6cc0a0ef356872ca94f
ToppCell	3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPSAB1 SEMA7A TPSG1 PADI2 TPSB2 RIC1	1.83e-05	172	141	6	a3d431aed12c1192e8dca1dc85b8340fb7354f8d
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KREMEN2 PORCN ITIH5 TYRO3 TECPR2 RNF208	1.83e-05	172	141	6	1bbf5ed7d13635f9a7e528060341e0652699bd7c
ToppCell	3'-Airway_Nasal-Immune_Myeloid_mast\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPSAB1 SEMA7A TPSG1 PADI2 TPSB2 RIC1	1.83e-05	172	141	6	028a5441242b2cc760cafc1822120180619c63ae
ToppCell	3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPSAB1 SEMA7A TPSG1 PADI2 TPSB2 RIC1	1.83e-05	172	141	6	9fc70b1a143a8ec910336c23b761d908bb6aecb2
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-cDC2\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LILRA1 CFP MLKL CD1D SLC37A2 RNF208	2.29e-05	179	141	6	1016af3d61a9276a792629f8b1a28a93038e29c1
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SSPOP HSPB9 FBN2 TECPR2 PRSS27 WDR17	2.52e-05	182	141	6	dfde2d9950f445c6c936ac828f7210de87bb45ec
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SSPOP HSPB9 FBN2 TECPR2 PRSS27 WDR17	2.52e-05	182	141	6	52274af3136d4fd4a495f5882618444661421f0f
ToppCell	PCW_05-06-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CASP1 CFP MLKL CD1D HAL RGL4	2.59e-05	183	141	6	aed12b743334f3813db0c70d4fe7df90e0673f54
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Pdyn_(Striatum,_patch_dSPNs)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PRSS33 F7 TEX101 GZMK	2.78e-05	55	141	4	6575ee5274f1044e17f4a5204375acc82ef16182
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Pdyn_(Striatum,_patch_dSPNs)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PRSS33 F7 TEX101 GZMK	2.78e-05	55	141	4	21a72cc6f12889509dbfaa9929be48d00f5f6345
ToppCell	10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-basophil\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TPSAB1 SEMA7A CR1 TEX101 ADGRE1 TPSB2	3.02e-05	188	141	6	b4d695c373195d389e0a579e9589e87433286b24
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LILRA1 CASP1 CDH23 CFP HAL ADGRE1	3.49e-05	193	141	6	cb0fb21510124883e716780bea46575620c366b8
ToppCell	Children_(3_yrs)-Immune-monocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LILRA1 DISC1 CFP CR1 CD1D FBN2	3.49e-05	193	141	6	58e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LILRA1 CASP1 CDH23 CFP HAL ADGRE1	3.49e-05	193	141	6	0c207879f994c227dcd1322faa69ec9e3749cdaa
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LILRA1 CASP1 CDH23 CFP HAL ADGRE1	3.49e-05	193	141	6	0fbbfcc803edc3cd96b35467ad5cc573af07fd67
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Fos_(iSPN,_IEG+)\|Striatum / BrainAtlas - Mouse McCarroll V32	SELE F7 PRSS46P MALRD1	3.68e-05	59	141	4	a72de8cda377c87fa9a6fbda72735d850650f9f4
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Fos_(iSPN,_IEG+)-\|Striatum / BrainAtlas - Mouse McCarroll V32	SELE F7 PRSS46P MALRD1	3.68e-05	59	141	4	3ab024fa7a927177da0dc764cee46dabdd008040
ToppCell	distal-Hematologic-Nonclassical_Monocyte\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRA1 CASP1 CDH23 CFP HAL ADGRE1	3.70e-05	195	141	6	6f417bb464b8ae6a50bbab5db5a6d5760c02122f
ToppCell	Adult-Immune-monocyte-D231\|Adult / Lineage, Cell type, age group and donor	LILRA1 DISC1 CDH23 CFP CD1D PADI2	3.70e-05	195	141	6	ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCell	distal-1-Hematologic-Nonclassical_Monocyte\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRA1 KREMEN2 CDH23 CFP HAL ADGRE1	3.70e-05	195	141	6	e1a8171d1af53c2bbda758170c5053d3a3bb6ddd
ToppCell	distal-Hematologic-Classical_Monocyte-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRA1 CFP CR1 CD1D FBN2 HAL	3.70e-05	195	141	6	32c34741e35006b7238896fd04a497011297dd22
ToppCell	LAM-Myeloid-Monocyte\|LAM / Condition, Lineage and Cell class	LILRA1 CASP1 CDH23 CFP CD1D ADGRE1	3.70e-05	195	141	6	7ef400e068e730e18bbdb86f2daa7caf82602349
ToppCell	LPS-IL1RA-Unknown-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GRM2 WIZ PKD1 ACKR1 WDR17	3.71e-05	118	141	5	aefad0b35aff980b6a2a98057735442e8a65ab04
ToppCell	LPS-IL1RA-Unknown\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GRM2 WIZ PKD1 ACKR1 WDR17	3.71e-05	118	141	5	6cb4063b83f867b782080ce5b1199b51bb277f2a
ToppCell	Adult-Immune-monocyte\|Adult / Lineage, Cell type, age group and donor	LILRA1 DISC1 CDH23 CFP CD1D PADI2	3.81e-05	196	141	6	3ef193c5180de3137daf886492e74fc574bc9767
ToppCell	BLOOD--(3)_Non_classical_monocytes\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	LILRA1 CASP1 CDH23 CFP KLK3 ADGRE1	3.81e-05	196	141	6	b5ce99e27c9e87be52c10c022a665bf4df0e8b05
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-Monocytes\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LILRA1 CASP1 CFP CR1 CD1D RGL4	3.81e-05	196	141	6	4354ee481053e7b02e8c0bb16ea4377566ef2b53
ToppCell	distal-2-Hematologic-Classical_Monocyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRA1 CFP CR1 CD1D FBN2 HAL	3.92e-05	197	141	6	9a1c9221904ad1e46e64e3785516804e87128adc
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SELE SEMA3F HSPG2 SEMA7A ITIH5 HMCN1	4.14e-05	199	141	6	d95d78b2ebc9a20532466e4d4be579b4faf6776f
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SELE SEMA3F HSPG2 SEMA7A ITIH5 HMCN1	4.14e-05	199	141	6	cdcfca94baba66e213cc3ffb0cfb4c75d6ab44ec
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SELE SEMA3F HSPG2 ITIH5 IGFBP1 HMCN1	4.14e-05	199	141	6	0602e2b2aa56d106da63bd342a38bef437b4d496
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LILRA1 CDH23 CFP CR1 CD1D ADGRE1	4.14e-05	199	141	6	ac866ae110967c5867ff4601939b79861d43df54
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-MAIT\|ICU-SEP / Disease, condition lineage and cell class	TMEM67 ACACB FSD1 THOC3 GZMK TRMT12	4.14e-05	199	141	6	2f10622319c6146dfed8cfe3844180c1e1d56e94
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Reln_(Neuron.Gad1Gad2.Cplx3-Reln)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GPR6 MUC19 IGFBP1 SLC6A20	4.20e-05	61	141	4	06aab3f1743ced1e46d22f0310f1cdb70c7a108e
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Reln_(Neuron.Gad1Gad2.Cplx3-Reln)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GPR6 MUC19 IGFBP1 SLC6A20	4.20e-05	61	141	4	fec6c9a4e12c260338856567bf547f914f473dbb
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	DISC1 CASP1 SLC40A1 ITIH5 IRF9 CD1D	4.26e-05	200	141	6	25f4c051c2e869481f33c22ad54de97efac444ad
ToppCell	Control-Control-Lymphocyte-T/NK-CD8+_T_naive\|Control / Disease, condition lineage and cell class	ZNF609 OBSCN PCED1B FCGBP ROBO1 RGL4	4.26e-05	200	141	6	906de95adc9716982ab32f216dddeb52639bad06
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LILRA1 DISC1 CDH23 CFP CR1 ADGRE1	4.26e-05	200	141	6	8872d5fa101d413fb43b4231d476878678543035
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial-Proteoglycan-expressing_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	DISC1 CASP1 SLC40A1 ITIH5 IRF9 CD1D	4.26e-05	200	141	6	da45a85a4667965b24ba824af871157af5b4cd19
ToppCell	severe-CD163+_Monocytes_(Sample_ID1_d7)\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	LILRA1 TMEM144 CFP CR1 CD1D FBN2	4.26e-05	200	141	6	4943fe826d5fcc3dfeb8b99a7415848f3fecc994
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SVEP1 HMCN1 DACT3 ROBO1 SMO ALDH1A3	4.26e-05	200	141	6	54806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TTC24 MUC19 HSPB9 FCGBP	7.22e-05	70	141	4	986c7a1002a4ffd3a246495bedde2997ffdc2c9d
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TTC24 MUC19 HSPB9 FCGBP	7.22e-05	70	141	4	c0330216305491d7d57cdbea0ae3cb8e9092c8e3
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P3\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TTC24 MUC19 HSPB9 FCGBP	7.22e-05	70	141	4	86dde790fcdaec2095e2256463953077811145d2
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TTC24 MUC19 HSPB9 FCGBP	7.22e-05	70	141	4	e604660b2efbc03e21806dcaecf7a72321673ae2
ToppCell	TCGA-Blood_and_Bone_Marrow-Primary_Blood_Derived_Cancer_-_Peripheral_Blood-Leukemia-Acute_Myeloid_Leukemia-3\|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9	LILRA1 PELI3 CASP1 CFP CD1D	7.29e-05	136	141	5	4f5e0b6c7d6e3e922af4daa7c3eb56490455c1df
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Rectal_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	KLK11 KLK3 FCGBP TPSG1 KLK2	7.81e-05	138	141	5	e1e936ff4080bda2810c5fd1154a706359f377a5
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMEM144 TLCD4 MALRD1 CCDC157 ARHGAP33	8.94e-05	142	141	5	5690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PRSS33 NLRP6 TEX101 GZMK	1.05e-04	77	141	4	10969743351c49a1d6d8ae1ef93098e7786ca3fe
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 OVCH2 PELI3 SSPOP GEN1	1.16e-04	150	141	5	afd651c654e715414eff64cf3a37378d057a56a2
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3-Excitatory_Neuron.Slc17a7.Pvrl3-Fos_(CA3_Principal_cells)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GNB1L F7 IGFBP1 ALDH1A3	1.22e-04	80	141	4	b661644806e225f215047e78ae46d7cee6efde4f
ToppCell	Severe-B_naive-5\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PELI3 FSD1 SLC40A1 PIGR DACT3	1.27e-04	153	141	5	44572f87d403e314050ab935d2cd676c33d9c287
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LILRA1 CFP SLC35G6 FBN2 OR52A1	1.27e-04	153	141	5	5fbb90b8477f9fdabf3be19efd3068fbf70abee6
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LILRA1 CFP SLC35G6 FBN2 OR52A1	1.27e-04	153	141	5	2c46183481e6d5a7fa190a743062509465f88e56
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	LILRA1 CFP SLC35G6 FBN2 OR52A1	1.27e-04	153	141	5	decc4f3098a9374a6b65c015a9d36380986290bf
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LILRA1 CFP SLC35G6 FBN2 OR52A1	1.27e-04	153	141	5	36a28805c0545c2f410c74a6ca0a70d840e75715
ToppCell	Severe-B_naive-5\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PELI3 FSD1 SLC40A1 PIGR DACT3	1.43e-04	157	141	5	a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS56 ARHGEF10L AP1G2 ADGRE1 PADI2	1.48e-04	158	141	5	b0508a600994090c6aafd8d779437190a33ad821
ToppCell	facs-Lung-EPCAM-3m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS56 ARHGEF10L AP1G2 ADGRE1 PADI2	1.48e-04	158	141	5	a816cc095452308d06f87b77467e2a8c6361fd2a
ToppCell	Adult-Immune-mast_cell-D175\|Adult / Lineage, Cell type, age group and donor	SEMA7A CDK5RAP1 LPAR2 ADGRE1 RNF208	1.52e-04	159	141	5	9f53fe2e0f25448d62a591c8e528e9a49b5400d5
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TMEM67 DISC1 OBSCN GZMK DACT3	1.61e-04	161	141	5	58381131e651744b5141b202f9d6063f55432db5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TPSAB1 SEMA7A DACT3 TPSG1 TPSB2	1.61e-04	161	141	5	c54010d88f1ecb6e0235bb66084876a4d5bf1ecd
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	MRM1 FSD1 CR1 TYRO3 SMO	1.66e-04	162	141	5	a957c7e347189b72fbd47db3075bb5e879a21c67
ToppCell	mild-Myeloid-Eosinophils\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SEMA7A PRSS33 TEX101 ADGRE1 TPSB2	1.71e-04	163	141	5	7c57d541a88e9afa079e95b8a6ecdea60a0c6aaa
ToppCell	Control-APC-like-Monocytes\|Control / group, cell type (main and fine annotations)	LILRA1 FOXRED1 THOC3 SMO LRRC7	1.71e-04	163	141	5	4bc80a2c741d462724b6f3902377d48c57478932
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THOC3 MMACHC CDK5RAP1 ESPL1 ARHGAP33	1.76e-04	164	141	5	4307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KREMEN2 CFP URB2 SLC37A2 ACKR1	1.76e-04	164	141	5	54f8f11d2fa899005530c08e7a1ee728c7b0799c
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THOC3 MMACHC CDK5RAP1 ESPL1 ARHGAP33	1.76e-04	164	141	5	1d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC29A3 CFP SLC40A1 SLC37A2 ADGRE1	1.81e-04	165	141	5	47e716ce8dc283d406352c1909e09362fcb9e3a3
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC29A3 CFP SLC40A1 SLC37A2 ADGRE1	1.81e-04	165	141	5	fe2135fdacf3807eb4b5ea5e790febfb8cd54335
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC29A3 DISC1 PLAA CDK5RAP1 SLC37A2	1.86e-04	166	141	5	de319c960b0cd90b294f677d1ea1b013a2ce2d53
ToppCell	10x5'-lymph-node_spleen-Mast-Mast_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	TPSAB1 MALRD1 TEX101 TPSG1 TPSB2	1.96e-04	168	141	5	650ad3ea52577887885d82457dbc04202ce3eb34
Computational	Genes in the cancer module 12.	SEMA3F ABHD14A CFP F7 CRHR2 FBN2 CSH2 PIGR LPAR2 HAL ADGRE1 ESPL1 ACKR1	6.21e-05	519	76	13	MODULE_13
Computational	Neighborhood of TNFRSF1B	LILRA1 CASP1 CFP CD1D ADGRE1	9.18e-05	65	76	5	GNF2_TNFRSF1B
Computational	Serine proteases.	TPSAB1 GZMK TMPRSS2 KLK2	1.57e-04	39	76	4	MODULE_109
Computational	Neighborhood of CD1D	LILRA1 CASP1 CFP CD1D	2.76e-04	45	76	4	GNF2_CD1D
Computational	Neighborhood of TIMP2	SVEP1 FBN2 IGFBP1 CSH1	3.01e-04	46	76	4	GNF2_TIMP2
Computational	Neighborhood of KISS1	SVEP1 FBN2 IGFBP1 CSH1	3.84e-04	49	76	4	GNF2_KISS1
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KLK11 KLK3 TMPRSS2 KLK2	4.15e-04	50	76	4	GAVISH_3CA_METAPROGRAM_EPITHELIAL_ANDROGEN_PROSTATE
Computational	Neighborhood of CD33	LILRA1 CASP1 CFP CD1D	4.83e-04	52	76	4	GNF2_CD33
Drug	benzamidine	KLK11 TPSAB1 KLK3 F7 IGFBP1 PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	1.10e-10	147	139	12	CID000002332
Drug	Z-ARR-AFC	TPSAB1 TPSG1 CTRL KLK2 TPSB2	9.76e-09	13	139	5	CID000125067
Drug	ioxaglate	TPSAB1 TYRO3 TPSG1 TPSB2	4.59e-08	7	139	4	CID000003742
Drug	isocoumarin	TPSAB1 F7 GZMK TPSG1 CTRL TPSB2	1.28e-07	39	139	6	CID000068108
Drug	Leupeptin hydrochloride	KLK11 TPSAB1 CASP1 KLK3 PIGR PRSS27 CAPN7 TMPRSS2 TPSG1 CTRL KLK2 TPSB2	1.35e-07	276	139	12	CID000003910
Drug	LY 294002; Down 200; 10uM; HL60; HT_HG-U133A	ABCA2 MAP4 MRM1 URB2 CR1 CD1D LPAR2 HAL ADGRE1 CTRL	2.23e-07	186	139	10	6198_DN
Drug	AC1NUP69	TPSAB1 TPSG1 CTRL TPSB2	2.72e-07	10	139	4	CID005487154
Drug	Z-ala-ala-lys-mna	TPSAB1 TPSG1 CTRL TPSB2	4.25e-07	11	139	4	CID005486901
Drug	4-amidinophenylpyruvic acid	TPSAB1 TPSG1 KLK2 TPSB2	6.34e-07	12	139	4	CID000151496
Drug	diisopropylfluorophosphate	KLK11 TPSAB1 GARS1 KLK3 F7 PRSS27 GZMK TMPRSS2 TPSG1 CTRL KLK2 TPSB2	6.77e-07	321	139	12	CID000005936
Drug	merbarone	KLK3 TMPRSS2 KLK2	8.87e-07	4	139	3	ctd:C045459
Drug	Brunfelsamidine	TPSAB1 TPSG1 TPSB2	8.87e-07	4	139	3	CID005281683
Drug	AC1Q6PMP	KLK11 TPSAB1 CASP1 KLK3 CSH1 CAPN7 TPSG1 CTRL TPSB2	9.92e-07	169	139	9	CID000103535
Drug	methylimidazoleacetic acid	TPSAB1 ALDH1A3 TPSG1 TPSB2	2.98e-06	17	139	4	CID000075810
Drug	chloromethyl	KLK11 TPSAB1 CASP1 F7 CAPN7 GZMK TPSG1 CTRL TPSB2	3.24e-06	195	139	9	CID000007835
Drug	Ginkgolide A [15291-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A	SEMA3F HSPG2 ABCA2 ACACB KREMEN2 TMEM212 SVEP1 GZMK KLK2	3.52e-06	197	139	9	4121_UP
Drug	A80a	TPSAB1 GZMK TPSG1 TPSB2	5.97e-06	20	139	4	CID005487000
Drug	Telebrix	TPSAB1 TPSG1 TPSB2	7.66e-06	7	139	3	CID000034536
Drug	APMSF	KLK11 TPSAB1 F7 CTRL TPSB2	1.09e-05	48	139	5	CID000001719
Drug	LTC4 (leukotriene C4	TPSAB1 LILRA1 ABCC11 PRSS33 KLK3 TPSG1 KLK2 TPSB2	1.52e-05	180	139	8	CID000003907
Drug	daphnodorin C	TPSAB1 TPSG1 TPSB2	1.82e-05	9	139	3	CID000072428
Drug	Monobenzone [103-16-2]; Up 200; 20uM; MCF7; HT_HG-U133A	ZNF609 ACACB DISC1 KREMEN2 ITIH5 GZMK TMPRSS2 TPSG1	2.43e-05	192	139	8	3391_UP
Drug	1c5s	TPSAB1 TPSG1 TPSB2	2.59e-05	10	139	3	CID000444753
Drug	Alsterpaullone; Up 200; 10uM; MCF7; HT_HG-U133A	SEMA3F ABHD14A TMEM144 ABCA2 MAP4 KREMEN2 WIZ CTRL	2.61e-05	194	139	8	7051_UP
Drug	rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; PC3; HT_HG-U133A	TMEM144 ABCA2 DISC1 KREMEN2 ZNF205 URB2 IGFBP1 ARHGAP33	2.71e-05	195	139	8	5980_DN
Drug	Hesperetin [520-33-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A	ABHD14A ZNF609 MAP4 MRM1 TMEM212 ZNF205 SVEP1 ARHGEF10L	2.81e-05	196	139	8	5350_UP
Drug	Ethambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A	SEMA3F HSPG2 ZNF609 ACACB SVEP1 TECPR2 SLC6A20 TPSG1	2.92e-05	197	139	8	4120_UP
Drug	Diphenidol hydrochloride [3254-89-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A	SEMA3F ZNF609 TMC7 SEMA7A MAP4 KREMEN2 PIGR ARHGAP33	2.92e-05	197	139	8	7447_UP
Drug	Amidopyrine [58-15-1]; Down 200; 17.2uM; MCF7; HT_HG-U133A	SEMA3F SLC29A3 ABCA2 ZNF609 DISC1 GNB1L CASP1 TMPRSS2	3.02e-05	198	139	8	6818_DN
Drug	(S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; PC3; HT_HG-U133A	SEMA3F DISC1 TMEM212 ZNF205 FSD1 IGFBP1 WIZ AP1G2	3.13e-05	199	139	8	6343_UP
Drug	Tracazolate hydrochloride [41094-88-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A	HSPG2 ABCA2 ZNF609 TMC7 MAP4 MRM1 ZNF205 PLAA	3.13e-05	199	139	8	7339_DN
Drug	3-aminopropanal	CASP1 SMO ALDH1A3 TPSG1	3.22e-05	30	139	4	CID000000075
Drug	Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; MCF7; HT_HG-U133A	SEMA3F HSPG2 TMEM144 KREMEN2 TMEM212 GRM2 CRHR2 SLC6A20	3.25e-05	200	139	8	2314_UP
Drug	pimaradiene	TPSAB1 TPSG1 TPSB2	3.54e-05	11	139	3	CID000440909
Drug	daphnodorin A	TPSAB1 TPSG1 TPSB2	3.54e-05	11	139	3	CID000072426
Drug	AC1NSU64	TPSAB1 TPSG1 TPSB2	3.54e-05	11	139	3	CID005316303
Drug	methylhistamine	TPSAB1 TPSG1 TPSB2	3.54e-05	11	139	3	CID000000912
Drug	benzoylmetronidazole	PORCN PRSS27	3.70e-05	2	139	2	CID000083213
Drug	bis(5-amidino-2-benzimidazolyl)methane	TPSAB1 TPSG1 TPSB2	4.71e-05	12	139	3	CID000002386
Drug	Elocom	TPSAB1 TPSG1 TPSB2	4.71e-05	12	139	3	CID000123620
Drug	NSC-648146	TPSAB1 TPSG1 TPSB2	4.71e-05	12	139	3	CID000372649
Drug	2-vinyl benzaldehyde	TPSAB1 CASP1 GZMK TPSG1 CTRL TPSB2	5.34e-05	108	139	6	CID000039391
Drug	TLCK	TPSAB1 CASP1 KLK3 TPSG1 CTRL KLK2 TPSB2	5.38e-05	158	139	7	CID000004427
Drug	CI-U	SELE TPSAB1 TPSG1 TPSB2	6.01e-05	35	139	4	CID000004357
Drug	His-Leu	GZMK PKD1 CTRL KLK2	6.01e-05	35	139	4	CID000189008
Drug	atracurium	TPSAB1 PORCN TPSG1 TPSB2	6.01e-05	35	139	4	CID000047319
Drug	Nk3201	TPSAB1 CTRL TPSB2	6.09e-05	13	139	3	CID000213050
Drug	tele-methylhistamine	TPSAB1 HAL TPSG1 TPSB2	8.36e-05	38	139	4	CID000003614
Drug	GPGR	TPSAB1 TPSG1 CTRL TPSB2	8.36e-05	38	139	4	CID000485268
Drug	fexofenadine	TPSAB1 SLC47A2 TYRO3 TPSG1 TPSB2	8.49e-05	73	139	5	CID000003348
Drug	AC1NRA23	KLK11 TPSAB1 TMPRSS2 CTRL TPSB2	8.49e-05	73	139	5	CID005287657
Drug	azelastine	TPSAB1 PRSS33 FBN2 TPSG1 TPSB2	9.06e-05	74	139	5	CID000002267
Drug	NSC89634	TPSAB1 TPSG1 CTRL TPSB2	9.27e-05	39	139	4	CID000070877
Drug	Cp51	KLK3 CTRL KLK2	9.60e-05	15	139	3	CID000086345
Drug	FdTTP	TPSAB1 TPSG1 TPSB2	9.60e-05	15	139	3	CID000162005
Drug	thymidine glycol monophosphate	TPSAB1 TPSB2	1.11e-04	3	139	2	CID000165415
Drug	beta-carene	CSH2 CSHL1	1.11e-04	3	139	2	CID000011129
Drug	Phe-pro-arg	TPSAB1 F7 GZMK TPSB2	1.13e-04	41	139	4	CID000133189
Drug	H 17	TPSAB1 TPSG1 TPSB2	1.42e-04	17	139	3	CID000476867
Drug	Forskolin, from Coleus forskohlii; Up 200; 0.5uM; MCF7; HT_HG-U133A	SEMA3F ABHD14A HSPG2 ABCA2 ACACB MAP4 CASP1	1.44e-04	185	139	7	7055_UP
Drug	Isoconazole [27523-40-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A	SEMA3F TMC7 TMEM212 CASP1 SVEP1 GZMK TMPRSS2	1.54e-04	187	139	7	7211_UP
Drug	2-azetidinone	TPSAB1 TPSG1 TPSB2	1.70e-04	18	139	3	CID000136721
Drug	Bacampicillin hydrochloride [37661-08-8]; Up 200; 8uM; HL60; HT_HG-U133A	SEMA3F ABCA2 MAP4 CFP LPAR2 HAL PADI2	1.82e-04	192	139	7	1337_UP
Drug	Metixene hydrochloride [1553-34-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A	TMEM144 SEMA7A SVEP1 CRHR2 WIZ TECPR2 ARHGAP33	1.82e-04	192	139	7	3313_UP
Drug	Dirithromycin [62013-04-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A	SEMA3F ABHD14A ABCA2 MAP4 CASP1 ZNF205 OGDH	1.94e-04	194	139	7	2863_DN
Drug	Chicago sky blue 6B [2610-05-1]; Up 200; 4uM; PC3; HT_HG-U133A	HSPG2 ZNF609 MAP4 CASP1 MAU2 GZMK ARHGAP33	2.00e-04	195	139	7	6626_UP
Drug	Harmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; HL60; HT_HG-U133A	ABCA2 TMC7 MAP4 GRM2 CR1 HAL PADI2	2.00e-04	195	139	7	2149_UP
Drug	isomenthone	PRSS33 GRM2 KLK3	2.01e-04	19	139	3	CID000006986
Drug	estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A	SEMA3F ACACB GRM2 WIZ TECPR2 TMPRSS2 AP1G2	2.06e-04	196	139	7	5955_DN
Drug	17-AAG; Down 200; 1uM; PC3; HG-U133A	ACACB CASP1 KLK3 ARHGEF10L PIGR TRPM3 ADGRE1	2.06e-04	196	139	7	432_DN
Drug	Doxycycline hydrochloride [10592-13-9]; Down 200; 8.4uM; HL60; HT_HG-U133A	TMEM144 SLC29A3 ZNF609 MAP4 CR1 TECPR2 PADI2	2.06e-04	196	139	7	2737_DN
Drug	Probucol [23288-49-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A	ABCA2 ZNF609 MAP4 CASP1 FSD1 WIZ PADI2	2.06e-04	196	139	7	5261_DN
Drug	Pilocarpine nitrate [148-72-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A	SEMA3F ABCA2 ZNF609 MAP4 KREMEN2 LPAR2 ARHGAP33	2.06e-04	196	139	7	5341_UP
Drug	Nadide [53-84-9]; Down 200; 6uM; MCF7; HT_HG-U133A	ABHD14A DISC1 MRM1 GNB1L FSD1 WRAP73 ROBO1	2.13e-04	197	139	7	7227_DN
Drug	Homosalate [118-56-9]; Down 200; 15.2uM; MCF7; HT_HG-U133A	MAP4 DISC1 KREMEN2 GNB1L ZNF205 TECPR2 TMPRSS2	2.13e-04	197	139	7	4355_DN
Drug	estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A	SEMA3F GPR6 CASP1 SVEP1 PLAA TMPRSS2 PADI2	2.13e-04	197	139	7	5960_UP
Drug	Cefotetan [69712-56-7]; Up 200; 7uM; MCF7; HT_HG-U133A	HSPG2 TMEM212 CRHR2 GZMK TMPRSS2 HAL OR52A1	2.13e-04	197	139	7	4116_UP
Drug	Lovastatin [75330-75-5]; Down 200; 9.8uM; HL60; HT_HG-U133A	ABCA2 ACACB TMC7 MAP4 GNB1L TECPR2 ADGRE1	2.13e-04	197	139	7	2494_DN
Drug	Fluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; PC3; HT_HG-U133A	ZNF205 KLK3 CRHR2 FBN2 SLC6A20 AP1G2 OR52A1	2.13e-04	197	139	7	5741_UP
Drug	valdecoxib; Down 200; 10uM; PC3; HT_HG-U133A	ABCA2 ZNF609 MRM1 CASP1 SVEP1 WIZ TMPRSS2	2.13e-04	197	139	7	6408_DN
Drug	Stachydrine hydrochloride; Down 200; 22.2uM; MCF7; HT_HG-U133A	SEMA3F ABCA2 ZNF609 TMC7 CASP1 PLAA WIZ	2.13e-04	197	139	7	6805_DN
Drug	LY 294002; Up 200; 0.1uM; HL60; HT_HG-U133A	SELE TMEM212 F7 SVEP1 CRHR2 ITIH5 TPSG1	2.19e-04	198	139	7	6175_UP
Drug	Pempidine tartrate [546-48-5]; Down 200; 13uM; MCF7; HT_HG-U133A	HSPG2 ABCA2 ZNF609 TMC7 GNB1L PLAA ROBO1	2.19e-04	198	139	7	6027_DN
Drug	Nialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A	ZNF609 ACACB CRHR2 ITIH5 PIGR AP1G2 KLK2	2.19e-04	198	139	7	3790_UP
Drug	Zr-C	CSH2 CSHL1	2.20e-04	4	139	2	CID000449163
Drug	diloxanide furoate	PORCN PRSS27	2.20e-04	4	139	2	CID000019529
Drug	PF-00562151-00 [351320-12-2]; Down 200; 10uM; MCF7; HT_HG-U133A	ACACB SEMA7A CASP1 GRM2 CRHR2 AP1G2 TPSG1	2.26e-04	199	139	7	5954_DN
Drug	Cholecalciferol [67-97-0]; Down 200; 10.4uM; MCF7; HT_HG-U133A	SEMA3F ZNF609 MAP4 MRM1 KREMEN2 ZNF205 FSD1	2.26e-04	199	139	7	5002_DN
Drug	Pralidoxime chloride [51-15-0]; Up 200; 23.2uM; HL60; HT_HG-U133A	ZNF609 ACACB MAP4 URB2 ITIH5 PADI2 OR52A1	2.26e-04	199	139	7	3066_UP
Drug	gadolinium	CDH23 IGFBP1 CSH1 CSH2 CSHL1 TRPM3 PKD1	2.26e-04	199	139	7	CID000023982
Drug	2000 h	CFP CSH2 CSHL1 HAL	2.28e-04	49	139	4	CID006435908
Drug	Racecadotril [81110-73-8]; Up 200; 10.4uM; PC3; HT_HG-U133A	ZNF609 SEMA7A ITIH5 SLC6A20 AP1G2 HAL PADI2	2.33e-04	200	139	7	5755_UP
Drug	fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	ABCA2 TMC7 KREMEN2 URB2 OGDH PLAA WRAP73	2.33e-04	200	139	7	6996_DN
Drug	glutamate	MAP4 DISC1 GARS1 CASP1 PORCN GRM2 OGDH IRF9 MDN1 CSH1 TRPM3 PRSS27 PKD1 SLC6A5 HAL TPSG1	2.65e-04	962	139	16	CID000000611
Drug	Dutasteride	KLK3 TMPRSS2 KLK2	2.73e-04	21	139	3	ctd:D000068538
Disease	isolated growth hormone deficiency type II (implicated_via_orthology)	CSH1 CSH2 CSHL1	9.30e-07	5	135	3	DOID:0060872 (implicated_via_orthology)
Disease	isolated growth hormone deficiency (implicated_via_orthology)	CSH1 CSH2 CSHL1	3.23e-06	7	135	3	DOID:0060870 (implicated_via_orthology)
Disease	tryptase beta-2 measurement	TPSAB1 TPSG1 TPSB2	7.71e-06	9	135	3	EFO_0008306
Disease	congenital hypothyroidism (biomarker_via_orthology)	CSH1 CSH2 CSHL1	3.29e-05	14	135	3	DOID:0050328 (biomarker_via_orthology)
Disease	osteoporosis (biomarker_via_orthology)	CSH1 CSH2 CSHL1	1.35e-04	22	135	3	DOID:11476 (biomarker_via_orthology)
Disease	Tourette syndrome, bipolar disorder	TLCD4 MAU2	4.30e-04	7	135	2	EFO_0004895, MONDO_0004985
Disease	type 1 diabetes mellitus (implicated_via_orthology)	CSH1 CSH2 CSHL1	7.59e-04	39	135	3	DOID:9744 (implicated_via_orthology)
Disease	cystic kidney disease (implicated_via_orthology)	TMEM67 ROBO1	9.13e-04	10	135	2	DOID:2975 (implicated_via_orthology)
Disease	Russell-Silver syndrome	IGFBP1 CSH1	9.13e-04	10	135	2	C0175693
Disease	hyperglycemia (is_marker_for)	HSPG2 F7	1.57e-03	13	135	2	DOID:4195 (is_marker_for)
Disease	Connective Tissue Diseases	TPSAB1 PKD1	1.57e-03	13	135	2	C0009782
Disease	factor VII activating protease measurement	ZNF609 SLC37A3 MALRD1	2.07e-03	55	135	3	EFO_0009368
Disease	posterior thigh muscle volume	CSH1 CSHL1	2.10e-03	15	135	2	EFO_0020931
Disease	Malaria, susceptibility to	CR1 ACKR1	2.39e-03	16	135	2	cv:C1970028
Disease	–	CR1 ACKR1	2.39e-03	16	135	2	611162
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	TMEM67 PKD1	2.39e-03	16	135	2	DOID:0110861 (implicated_via_orthology)
Disease	cancer	NHLRC1 BPIFA3 KLK3 ARHGEF10L FBN2 CDK5RAP1 KLK2	2.51e-03	400	135	7	MONDO_0004992
Disease	familial hyperlipidemia (biomarker_via_orthology)	F7 IRF9	3.38e-03	19	135	2	DOID:1168 (biomarker_via_orthology)
Disease	macrophage inflammatory protein 1b measurement	SLC22A25 MAP4 MRM1 GRM2	3.59e-03	136	135	4	EFO_0008219
Disease	Malaria	CR1 ACKR1	3.74e-03	20	135	2	C0024530
Disease	urticaria	TPSAB1 TPSB2	3.74e-03	20	135	2	EFO_0005531
Disease	prothrombin time measurement	TTF2 F7	4.12e-03	21	135	2	EFO_0008390

Protein segments in the cluster

Peptide	Gene	Start	Entry
GAVLQLCSVPGARGW	URB2	1096	Q14146
GPLVCQKGNTWVLIG	CTRL	216	P40313
LLICQGLLWVGTDQG	ARHGEF10L	1071	Q9HCE6
NCVWKIVVPEGAGIQ	CSMD2	1821	Q7Z408
QDCVWLITVPIGHGV	CSMD2	2206	Q7Z408
AWAVGPVTIACLGAL	GRM2	566	Q14416
VCGGVLIDPQWVLTA	GZMK	51	P49863
WQCVSEALQILGGLG	ACAD9	391	Q9H845
IGVCGAITPWNFPLL	ALDH1A3	171	P47895
QPLVQVAAWCIGEYG	AP1G2	471	O75843
RVVQAWTCLPSAAGA	CFAP46	2591	Q8IYW2
LCLPWLQEAGAVQTV	CSHL1	16	Q14406
QLCPGWPVLAQLAVG	ACKR1	91	Q16570
LLVGRLEGAGQQVCW	CCDC157	411	Q569K6
VLISGCWGQVNRLPF	CDH23	16	Q9H251
QLQWQGCDLTPLVGQ	DISC1	496	Q9NRI5
QGTGSLAQVPLDKWC	ATG2B	41	Q96BY7
LNCVVPGQAHAQVTW	HSPG2	2171	P98160
LNCVVPGQAHAQVTW	HSPG2	2746	P98160
LCQNQVLGNPSWTVG	RABL3	26	Q5HYI8
QLHGVWPQDVVDGTC	RIC1	241	Q4ADV7
NCWPLLVIGGSSERN	HACL1	101	Q9UJ83
LTVPWVELGGECNIN	OSBPL9	566	Q96SU4
VATADLSNPLCGVWQ	KASH5	386	Q8N6L0
CLWGDPNVTVLAGLT	ABHD14A	61	Q9BUJ0
GGSWVVIDATINPLC	ACACB	2201	O00763
PLVCNGVLQGITSWG	KLK2	216	P20151
AAGQATIPEWCQGAA	MDN1	4031	Q9NU22
HGGQCVTWLQTLPQG	GNB1L	66	Q9BYB4
AVNPWDVLLCVSGTV	GPR6	71	P46095
CNTAVVPQGWSVEAL	MAP4	181	P27816
VIILGAFVVCWTPGQ	LPAR2	241	Q9HBW0
LVLPCNQSVVVGSWG	ITIH5	771	Q86UX2
NLGTVDVHPIGWCAI	L3MBTL2	261	Q969R5
QNDPQLAWGCISGLQ	LRRC7	521	Q96NW7
VWCGSFQVTTGLQVP	FSD1	461	Q9BTV5
PSGQLWVRGQCVALA	HSPB9	121	Q9BQS6
WVRGQCVALALPEAQ	HSPB9	126	Q9BQS6
LNASAQVAPGLVGWL	BPIFA3	66	Q9BQP9
LCLPWLQEAGAVQTV	CSH2	16	P0DML3
LTVQVGVTAGAPWQC	IGFBP1	16	P08833
LVGIPGLESVQCWIG	OR52A1	16	Q9UKL2
LIGIPGLESVQCWIG	OR52A5	16	Q9H2C5
SVILDPNWNGKVCGL	MUC19	1396	Q7Z5P9
GQVLPESCLLVWNTA	PCED1B	151	Q96HM7
LSWQQTCPGIVNGAL	ABCC11	481	Q96J66
QIGTCWPRSAAGALV	CRHR2	46	Q13324
RECWKQGQPVLVSGV	KDM3B	1406	Q7LBC6
CNQSLQGIISWGQDP	KLK11	241	Q9UBX7
QGIISWGQDPCAITR	KLK11	246	Q9UBX7
LQGPAQVECTTQGQW	SELE	341	P16581
VGSCQGNWTAPQGVI	KREMEN2	216	Q8NCW0
CSGKVAPGTLEWQLQ	CFP	111	P27918
TWGPEGQGAILLVNC	PADI2	141	Q9Y2J8
VCGGSLIAPQWVLTA	PRSS33	61	Q8NF86
EADPWGNQRISGVCI	MMACHC	136	Q9Y4U1
VLWEIATGDIPFQGC	MLKL	401	Q8NB16
LVCNANGIPTPLIQW	HMCN1	3266	Q96RW7
GATGVQWCLQGLPLQ	OBSCN	4186	Q5VST9
GCLLPTAQQGLDQIW	PORCN	16	Q9H237
VGLQTACGGPIQHLW	MALRD1	161	Q5VYJ5
FICPGQAKWVRQNGI	OGDH	761	Q02218
VALACWVGGLVPVLG	OR6S1	146	Q8NH40
LVFGVQVTCQGRSWP	ARHGAP33	81	O14559
GLVDSNLNCGPVLTW	ARHGAP33	151	O14559
AVLQGLWEENVCGTP	RGL4	21	Q8IZJ4
VCNGLVQTTGWPSVV	SLC37A2	151	Q8TED4
QLCAQGWQTPEIALI	ESPL1	926	Q14674
PCQDAQLTVGWLGRE	HAL	16	P42357
IIQACRGDSPGVVWF	CASP1	281	P29466
GGLVWPQQLVAATAA	DACT3	571	Q96B18
VQCPQGGAAVWVLLS	CAPN7	576	Q9Y6W3
VVLLALPVAWGQCNA	CR1	31	P17927
VQWLLNGTCPQFVSG	CD1D	176	P15813
QGWNNGGCPITAIVL	DSCAML1	1501	Q8TD84
CTFQGLQLAPGQEVW	FCGBP	801	Q9Y6R7
QEWGGAIPCQVVLVT	INTS14	101	Q96SY0
PVECAIVINAAGAWS	FOXRED1	281	Q96CU9
QCSAFVQLWAGLQPI	ABCA2	401	Q9BZC7
VQLWAGLQPILCGNN	ABCA2	406	Q9BZC7
LECLGIPWVQAAGEA	GEN1	121	Q17RS7
VVEQVESGQFPGVCW	IRF9	16	Q00978
LGCVVLWAQGTAGQP	FBN2	16	P35556
RAQVCGGQPWVTVLD	H1-9P	46	P60008
LCLPWLQEAGAVQTV	CSH1	16	P0DML2
IEGPWLRACGQTNVS	PRSS46P	26	E5RG02
GAVTLLANCVAPWAL	SLC22A25	386	Q6T423
PLLTLCGQIVENWQG	MAU2	206	Q9Y6X3
LSEGLAWPQCRVQTV	NLRP6	776	P59044
LCNPRGVAVSWLTGA	NHLRC1	261	Q6VVB1
WSVAQALLVLCPGTG	PKD1	4056	P98161
GQPLCGGVLVAASWV	PRSS56	126	P0CW18
WQTLEGGVLQLCPDT	TMEM67	346	Q5HYA8
CGRQLTAWIQVPGPN	SLC29A3	361	Q9BZD2
GPLVCKVNGTWLQAG	TPSAB1	226	Q15661
GPLVCKVNGTWLQAG	TPSB2	226	P20231
DSGGPLVCQVNGAWV	TPSG1	221	Q9NRR2
VNGECGNFVRLIQPW	SEMA3F	111	Q13275
TWQQVAPGELGLCEQ	SSPOP	4931	A2VEC9
TWPQVLSGVVGNCVN	SLC47A2	216	Q86VL8
SVWKAIPALQGCGIA	SLC6A5	261	Q9Y345
QGSPVTLWCQGILET	LILRA1	41	O75019
WQVLLLVNGAQLCGG	F7	226	P08709
QQGWLVAGTVGCPST	MRM1	216	Q6IN84
ICGGSIVSPQWVITA	OVCH2	76	Q7RTZ1
SAPGVWREISVCGNV	PELI3	251	Q8N2H9
GPVGCALKNNIIQTW	GARS1	151	P41250
LNPWIVLGGVATTVC	SEPHS1	166	P49903
PVIGCGFISGWNLVS	SLC40A1	201	Q9NP59
VGLLAAGCQPWNKDV	WDR17	31	Q8IZU2
RQFGVTEWCVNGSPI	WIZ	1421	O95785
LTGIEWAPNGCVLAV	WRAP73	181	Q9P2S5
LLGNPVLICQEDGTW	SVEP1	2691	Q4LDE5
VLICQEDGTWNGSAP	SVEP1	2696	Q4LDE5
QENGGVQWEPALCLL	SLC6A20	161	Q9NP91
ILGCSWVLGIFQIGP	ADGRE1	806	Q14246
CVLQVQRSLGWGPLA	CDK5RAP1	6	Q96SZ6
GWTLQVAPEEGQVLC	ZNF497	6	Q6ZNH5
QNVHVCGGSIITPEW	TMPRSS2	276	O15393
CWVPGEQATVLRNLG	TTC24	266	A2A3L6
CPIWNGALAITTGVL	TMEM212	46	A6NML5
WPSDTEIIVNQACGG	RNF208	66	Q9H0X6
NGLLQSTGWPCVVAV	SLC37A3	151	Q8NCC5
GGCIWATGNIAVVPI	TMEM144	71	Q7Z5S9
GPLVCLVGQSWLQAG	PRSS27	231	Q9BQR3
ICTIGIAPWGIVENQ	TRPM3	246	Q9HCF6
GECAQTIRLPAQSIW	PLAA	261	Q9Y263
NICWSPDGQTIAVGN	THOC3	146	Q96J01
TRCGGLPNNIVDVWE	TDP2	271	O95551
CEPGTSVNLEGIVWQ	ZNF609	306	O15014
ENGATCLPIPVWGLQ	TEX101	221	Q9BY14
LWGGPSLANVNIAIA	TLCD4	81	Q96MV1
SCWNLVNGTVVPLGE	SEMA7A	151	O75326
VWGVGLAGEQALPLC	SCART1	706	Q4G0T1
CQPSLLGVNNSGVWI	TECPR2	1076	O15040
QPAFIAGIGAACWII	ROBO1	896	Q9Y6N7
QNGRCPLLVDSEGWV	PIGR	391	P01833
PSWSCVGAVGILALV	SLC35G6	251	P0C7Q6
QLPRQKCLVAAGAWG	SMO	706	Q99835
CILGVTQKTIWTQGP	TIMM21	56	Q9BVV7
GRVQWGVPQCAQEAA	ZNF205	226	O95201
EGWPIACQVLRQDAG	TRMT12	316	Q53H54
IVRVCVSNAVGCGPW	TYRO3	391	Q06418
LSLLWAGPVNAGVTQ	TRBV6-5	11	A0A0K0K1A5
PDNVLGIVYGQTICW	TMC7	541	Q7Z402
LQACARWAVTGTPIQ	TTF2	756	Q9UNY4
FGVPCPSVQLWQGII	WDR54	211	Q9H977
PLVCNGVLQGITSWG	KLK3	216	P07288