Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3B RIMBP3C

8.58e-095203GO:0030156
GeneOntologyBiologicalProcessneuromuscular synaptic transmission

RIMBP3 RIMBP3B RIMBP3C

4.64e-0636193GO:0007274
GeneOntologyBiologicalProcessspermatid development

RIMBP3 RIMBP3B FSIP2 RIMBP3C

8.49e-05262194GO:0007286
GeneOntologyBiologicalProcessspermatid differentiation

RIMBP3 RIMBP3B FSIP2 RIMBP3C

9.81e-05272194GO:0048515
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3B RIMBP3C

2.82e-0628213GO:0002177
MousePhenoectopic manchette

RIMBP3 RIMBP3B RIMBP3C

1.43e-0619173MP:0009377
MousePhenodetached sperm flagellum

RIMBP3 RIMBP3B RIMBP3C

1.96e-0621173MP:0008893
MousePhenodetached acrosome

RIMBP3 RIMBP3B RIMBP3C

1.92e-0544173MP:0009231
MousePhenoabnormal manchette morphology

RIMBP3 RIMBP3B RIMBP3C

2.05e-0545173MP:0009376
MousePhenokinked sperm flagellum

RIMBP3 RIMBP3B RIMBP3C

3.98e-0556173MP:0009237
MousePhenoabnormal sperm nucleus morphology

RIMBP3 RIMBP3B RIMBP3C

9.18e-0574173MP:0009232
MousePhenoabnormal sperm flagellum morphology

RIMBP3 RIMBP3B FSIP2 RIMBP3C

3.72e-04295174MP:0008892
MousePhenoabnormal acrosome morphology

RIMBP3 RIMBP3B RIMBP3C

8.73e-04159173MP:0008898
MousePhenoabnormal motile cilium morphology

RIMBP3 RIMBP3B FSIP2 RIMBP3C

8.74e-04370174MP:0013206
DomainFN3

RIMBP3 RIMBP3B TIE1 RIMBP3C COL12A1

2.31e-06199215PS50853
DomainFN3_dom

RIMBP3 RIMBP3B TIE1 RIMBP3C COL12A1

2.94e-06209215IPR003961
DomainGrowth_fac_rcpt_

ADGRE2 TIE1 EYS NOTCH1

2.51e-05156214IPR009030
DomainFN3

RIMBP3B TIE1 RIMBP3C COL12A1

4.89e-05185214SM00060
Domain-

RIMBP3 RIMBP3B TIE1 CEACAM19 RIMBP3C COL12A1

6.72e-056632162.60.40.10
DomainSH3_9

RIMBP3 RIMBP3B RIMBP3C

8.83e-0578213PF14604
DomainIg-like_fold

RIMBP3 RIMBP3B TIE1 CEACAM19 RIMBP3C COL12A1

9.52e-05706216IPR013783
DomainSH3_2

RIMBP3 RIMBP3B RIMBP3C

1.18e-0486213IPR011511
DomainSH3_2

RIMBP3 RIMBP3B RIMBP3C

1.18e-0486213PF07653
DomainEGF

ADGRE2 TIE1 EYS NOTCH1

1.24e-04235214SM00181
DomainEGF_3

ADGRE2 TIE1 EYS NOTCH1

1.24e-04235214PS50026
DomainEGF-like_dom

ADGRE2 TIE1 EYS NOTCH1

1.54e-04249214IPR000742
DomainEGF_Ca-bd_CS

ADGRE2 EYS NOTCH1

1.69e-0497213IPR018097
DomainEGF_1

ADGRE2 TIE1 EYS NOTCH1

1.69e-04255214PS00022
DomainEGF_CA

ADGRE2 EYS NOTCH1

1.79e-0499213PS01187
DomainASX_HYDROXYL

ADGRE2 EYS NOTCH1

1.85e-04100213PS00010
DomainEGF-like_CS

ADGRE2 TIE1 EYS NOTCH1

1.85e-04261214IPR013032
DomainEGF_2

ADGRE2 TIE1 EYS NOTCH1

1.96e-04265214PS01186
DomainEGF-type_Asp/Asn_hydroxyl_site

ADGRE2 EYS NOTCH1

2.19e-04106213IPR000152
DomainEGF_CA

ADGRE2 EYS NOTCH1

3.32e-04122213SM00179
DomainEGF-like_Ca-bd_dom

ADGRE2 EYS NOTCH1

3.48e-04124213IPR001881
DomainEGF

TIE1 EYS NOTCH1

3.65e-04126213PF00008
DomainhEGF

EYS NOTCH1

4.47e-0428212PF12661
DomainSH3

RIMBP3 RIMBP3B RIMBP3C

1.74e-03216213PS50002
DomainSH3

RIMBP3 RIMBP3B RIMBP3C

1.74e-03216213SM00326
DomainSH3_domain

RIMBP3 RIMBP3B RIMBP3C

1.83e-03220213IPR001452
DomainLaminin_G

EYS COL12A1

1.92e-0358212IPR001791
DomainEGF_extracell

TIE1 NOTCH1

2.05e-0360212IPR013111
DomainEGF_2

TIE1 NOTCH1

2.05e-0360212PF07974
DomainEGF_CA

ADGRE2 NOTCH1

4.16e-0386212PF07645
Domain-

EYS COL12A1

5.05e-03952122.60.120.200
Domainfn3

TIE1 COL12A1

1.41e-02162212PF00041
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3B RIMBP3C

7.59e-10421319091768
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3B RIMBP3C

1.90e-09521317855024
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3B RIMBP3C

6.88e-081421317662146
Pubmed

Regulation of notch1 signaling by nrf2: implications for tissue regeneration.

NOTCH1 KEAP1

2.08e-06421220628156
Pubmed

RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1.

L3MBTL3 NOTCH1

2.08e-06421229030483
Pubmed

Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice.

NOTCH1 KEAP1

3.47e-06521229515034
Pubmed

Endothelial TIE1 Restricts Angiogenic Sprouting to Coordinate Vein Assembly in Synergy With Its Homologue TIE2.

TIE1 NOTCH1

2.70e-051321237317851
Pubmed

Klf2 is an essential regulator of vascular hemodynamic forces in vivo.

TIE1 NOTCH1

7.96e-052221217141159
Pubmed

HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development.

TIE1 NOTCH1

9.51e-052421221149574
Pubmed

Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping.

RIMBP3 HPS4

9.51e-052421211258795
Pubmed

Extra-embryonic vasculature development is regulated by the transcription factor HAND1.

TIE1 NOTCH1

1.30e-042821215073150
Pubmed

Dosage-dependent requirement for mouse Vezf1 in vascular system development.

TIE1 NOTCH1

1.40e-042921215882861
Pubmed

Ovol2/Movo, a homologue of Drosophila ovo, is required for angiogenesis, heart formation and placental development in mice.

TIE1 NOTCH1

1.40e-042921217573777
Pubmed

Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.

TIE1 NOTCH1

3.85e-044821228924218
Pubmed

GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.

TIE1 NOTCH1

5.82e-045921221421844
Pubmed

Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma.

NOTCH1 KEAP1

6.02e-046021231220272
Cytoband22q11.21

RIMBP3 RIMBP3B RIMBP3C

1.77e-0511121322q11.21
CytobandEnsembl 112 genes in cytogenetic band chr22q11

RIMBP3 RIMBP3B RIMBP3C

8.88e-04419213chr22q11
Cytoband19p13.2

MUC16 KEAP1

4.89e-0322921219p13.2
CytobandEnsembl 112 genes in cytogenetic band chr19p13

ADGRE2 MUC16 KEAP1

5.49e-03797213chr19p13
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF471 CEACAM19 SSC5D

1.64e-021192213chr19q13
GeneFamilyFibronectin type III domain containing

TIE1 COL12A1

5.69e-03160132555
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

ADGRE2 EYS SPHKAP

4.01e-051432130118772a5bc7c48465e9b314be55203412e8d67c
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ADGRE2 TIE1 NOTCH1

7.18e-05174213b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages|bone_marrow / Manually curated celltypes from each tissue

RIMBP3 CEACAM19 SSC5D

7.18e-051742130746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RIMBP3 RIMBP3B RIMBP3C

7.68e-0517821339889db130216655a34796e7030ffeb372465500
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_granulocytic-mast_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADGRE2 TIE1 MRGPRX2

8.34e-051832135ac38a2ce93c53f23a89faf287b81ea138560623
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TIE1 EYS NOTCH1

9.03e-05188213366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCellfacs-Lung|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRE2 TIE1 NOTCH1

9.03e-05188213f7292fc8e914f222828dcdb0a017d716207a97f6
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SSC5D TACC2 COL12A1

9.03e-05188213f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellfacs-Lung|facs / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRE2 TIE1 NOTCH1

9.03e-05188213e2b6e14579ec649a2bc106d9c99bb78ceb16ede3
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SSC5D TACC2 COL12A1

9.18e-05189213da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRE2 TIE1 NOTCH1

9.18e-051892131e1afa66b32ae752c0a42b02b80f10205464569c
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SSC5D TACC2 COL12A1

9.32e-05190213938d1f66094b1c94606e0d40213a39e5112f3322
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRE2 TIE1 NOTCH1

9.32e-051902133346bfd0474828b3729cffa9f4cc57b04dd30443
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRE2 TIE1 NOTCH1

9.32e-05190213eae5bcdb8a35f3fba4d25854c1a43f83f80832a2
ToppCellEndothelial-C|World / shred on cell class and cell subclass (v4)

ADGRE2 TIE1 NOTCH1

9.47e-05191213bf203931f973098b79ec681d1dd0854419819e98
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE2 SSC5D COL12A1

9.47e-051912131caf726bd07fdca389e678fc16304a6ef1790423
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE2 SSC5D COL12A1

9.47e-051912133d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRE2 TIE1 NOTCH1

9.62e-051922134bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SSC5D TACC2 COL12A1

9.76e-05193213000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRE2 TIE1 NOTCH1

9.91e-05194213f159ef8541d75a4e98468947f231bb463bec922c
ToppCellfacs-Lung-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRE2 TIE1 NOTCH1

9.91e-051942133b5ba12375102598468cb09e66af9241b66c3cf9
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SSC5D TACC2 COL12A1

9.91e-0519421367f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TIE1 NOTCH1 COL12A1

1.08e-04200213dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellmLN-(7)_Mast_cell-(70)_Mast|mLN / shred on region, Cell_type, and subtype

ADGRE2 TIE1 ZNF471

1.08e-04200213a6c258cae678be581b1d85cf3446c65c34b13499
ToppCellmLN-Mast_cell-Mast|mLN / Region, Cell class and subclass

ADGRE2 TIE1 ZNF471

1.08e-0420021381ea6e7a3940277751faf9097b30198159998c7b
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

SSC5D TACC2 SPHKAP

1.08e-0420021302cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCellmLN-Mast_cell|mLN / Region, Cell class and subclass

ADGRE2 TIE1 ZNF471

1.08e-042002139a5f1d99d8d160923d4d0fbbf9ad48a26f8a4fad
ToppCellmLN-(7)_Mast_cell|mLN / shred on region, Cell_type, and subtype

ADGRE2 TIE1 ZNF471

1.08e-0420021313bca944fbdbc0be6687eca82c62a4d231ab94f0
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_and_Papillary_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

RIMBP3 RIMBP3C

1.10e-03105212cfd271e2cd004d6815bcc3ce7cad86fe62b5299b
ToppCellStriatum-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Striatum / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

1.19e-03109212f4b9fe5335cabe48a5fae7ec51bab0d7bdb17321
ToppCellStriatum-Endothelial-ENDOTHELIAL_TIP|Striatum / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

1.19e-03109212a84a4a3ac19692e5595b9820d49e12ae336f4bbf
ToppCellStriatum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-|Striatum / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

1.19e-03109212f7d7b67f7585f2ae0ac905bcf3980264cf9234b8
ToppCellStriatum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Striatum / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

1.19e-03109212f007fa3dc92d6c8543585e47ccec218263b3266e
ToppCellStriatum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)|Striatum / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

1.19e-031092128460683529759585bd363d10a16ee13af2bd4e28
ToppCellControl-B_naive-4|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ADGRE2 SSC5D

1.34e-0311621235d471c8dbf408d0be3837c428d9c2a73c805a6f
ToppCellPBMC-Mild-Hematopoietic-RBC-RBC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RIMBP3 MRGPRX2

1.50e-03123212cc26155c55e400a0219c5f7f8217aa9c3c912e4e
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KIAA1210 SSC5D

1.50e-0312321228be15b759c152662b29c323b1cc3f02f7830dbe
ToppCellPBMC-Mild-Hematopoietic-RBC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RIMBP3 MRGPRX2

1.50e-031232127cccdc84130452fa48de47603ab1cc785a0a8c1a
ToppCellPBMC-Mild-Hematopoietic-RBC-RBC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RIMBP3 MRGPRX2

1.50e-031232129649daf3af2ba6fda4b14925ed03e469496b7a7b
ToppCellPBMC-Mild-Hematopoietic-RBC-RBC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RIMBP3 MRGPRX2

1.50e-03123212253e401bc546574e0c4a443b3082fb53b4d5ef60
ToppCellPBMC-Mild-Hematopoietic-RBC-RBC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RIMBP3 MRGPRX2

1.50e-031232128ad6bca3053d1d001f8c34a58374f14c224bf2e7
ToppCellPBMC-Mild-Hematopoietic-RBC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RIMBP3 MRGPRX2

1.50e-031232124960a126a878791c6bd190d030a9fecd164e9a24
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Cerebellum / BrainAtlas - Mouse McCarroll V32

RIMBP3 SSC5D

1.58e-0312621283f3540683b3b175b10af059ab8898c46eaccc13
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

RIMBP3 SSC5D

1.58e-03126212f20424f9baf3c4059cd6b701761e7595400fc47c
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)|Cerebellum / BrainAtlas - Mouse McCarroll V32

RIMBP3 SSC5D

1.58e-031262126d5075d659dac7b96e6857f8485a7d2c4105d685
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

RIMBP3 SSC5D

1.58e-03126212fd0001a0f3a0a4421f96fd21813c21cf6f01d40e
ToppCelldroplet-Heart-nan-18m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOTCH1 SPHKAP

1.58e-03126212de09142c12fd2ad6ecc3e7707015582f751eb426
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CEACAM19 TACC2

1.68e-031302126434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF471 CEACAM19

1.70e-0313121296d300958545714d18e905e860e95469c8ae4efa
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

1.73e-03132212560e836764ed7806fb18282dfebe434d30112a9a
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

1.73e-03132212893b7ec2a2d8a140cc98575d1beca1189f053e9a
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

1.78e-03134212d29ac8152dc581c0da2430d06cd259ac0eded808
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

1.78e-03134212459c39df15d3cf9144ce7827e8d14830d31353bb
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

1.78e-03134212d065449ca3679e4818b74fb7302cc7f1ce62f691
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

1.78e-03134212b959899c89d3a0363a3cd2309155280e0fe5ba88
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)|Cerebellum / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

1.78e-031342120be389f416818a22e80098dd809fdf45b14171e8
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RIMBP3B MUC16

1.83e-0313621227a41463e6f16deb5b1d4f17fefded9959038c07
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RIMBP3B MUC16

1.83e-0313621288b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

MUC16 EYS

1.91e-0313921264c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZNF471 CEACAM19

1.94e-03140212a88dbe7bf3e1419e360ab0b8cf24681d3424c3a7
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TIE1 NOTCH1

1.94e-03140212b9aeb7dda7f377b580dd8a44912f300721437387
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RIMBP3 SPHKAP

2.17e-031482125983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP|Cerebellum / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

2.20e-031492123980fa4f1986a2f164a1826ea043fb71f1d756cd
ToppCellmild_COVID-19_(asymptomatic)-NK_CD56bright|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

TIE1 FSIP2

2.25e-031512122470162f4b56bc505db166a6eb0fa54847759df8
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

MUC16 TACC2

2.25e-031512128216462e723fec2797387929dde095370947e10a
ToppCellfacs-Trachea-nan-24m-Myeloid-granulocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRE2 MRGPRX2

2.25e-0315121226fd55efb647c41436416d45952ee97b050e632c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-stem_cells_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

ADGRE2 ZNF471

2.28e-03152212375c9ef88c7703a002e868645a722c35e046ef1e
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Thalamus / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

2.31e-03153212e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GTPBP10 SSC5D

2.31e-0315321232cf4ca828d228f23366480305592f9813fed7ff
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Thalamus / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

2.31e-03153212b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCellThalamus-Endothelial-ENDOTHELIAL_TIP|Thalamus / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

2.31e-031532122513edfae62a44e51d3556675a096723194c966c
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GTPBP10 SSC5D

2.31e-03153212d5f5399ebbbff508c96ce7f01272716b61597ab5
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FSIP2 TACC2

2.37e-0315521277fdae85d36efb776db977eb424b32487ef222e4
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRGPRX2 SPHKAP

2.37e-031552128fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellNS-moderate-d_07-13-Myeloid-Mast_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TIE1 RIMBP3C

2.40e-0315621217c38d3b03fc38cb125cf0d165b2fd694cd88edd
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TIE1 RIMBP3C

2.43e-031572124183dbed6b31ebe13ef33eb19ba6d0fb4f625953
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EYS NOTCH1

2.43e-03157212c779a53b2c67d566f5d417e753cd17196a6bfd1c
ToppCellfacs-Trachea-24m-Hematologic-myeloid-granulocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRE2 MRGPRX2

2.43e-03157212188d2f85babcd4eefe20e7a392d851b2e1185bab
ToppCellSevere-B_naive-5|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FSIP2 CEACAM19

2.43e-03157212a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ZNF471 SPHKAP

2.46e-031582121f94622186d8329357fa06785e03eeacf29ab1ce
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FSIP2 CEACAM19

2.46e-0315821241cf950983f47a9e55d56041b301006b42853b37
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

2.49e-03159212cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

2.49e-0315921292049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCell343B-Myeloid-Mast_cell-|343B / Donor, Lineage, Cell class and subclass (all cells)

ADGRE2 MRGPRX2

2.52e-03160212a2f09b5955602819c8978f4372130c8ef915cd07
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPHKAP COL12A1

2.52e-03160212c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellNS-critical-d_16-33-Myeloid-Mast_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TIE1 SSC5D

2.52e-03160212c61869d9dbba250270e59366e15af204e5b4395d
ToppCellNS-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TIE1 SSC5D

2.52e-031602128a4746463ca1976f7d6de803496c851249ced797
ToppCellIPF-Epithelial-Ionocyte|IPF / Disease state, Lineage and Cell class

MUC16 TACC2

2.52e-03160212d65d19f4fae60836bfd4303a1bb7de34e9d83e35
ToppCell343B-Myeloid-Mast_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

ADGRE2 MRGPRX2

2.52e-03160212133ecae0a894d9a0d49d58859623359096b6f030
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPHKAP COL12A1

2.52e-0316021225c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5_FEZF2_DYRK2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPHKAP COL12A1

2.52e-03160212e2504c6deba4949a3a716a9ca68755f787bc0ae0
ToppCellIPF-Epithelial-Ionocyte|World / Disease state, Lineage and Cell class

MUC16 TACC2

2.56e-03161212f1cd5c938cdc08ad8995371b72493850a6cf277a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TIE1 NOTCH1

2.62e-031632121feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TIE1 NOTCH1

2.62e-0316321273c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCellwk_20-22-Hematologic-Myeloid-HSC/ELP|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADGRE2 RIMBP3C

2.65e-031642123c07d8f53511f269540bf032738a4ada35650b18
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-MEP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RIMBP3 TIE1

2.65e-0316421247355439e578d1b1a387fb4ee761162028abea4a
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

2.68e-03165212570483b43ccb5831feec9337b4664814431d40b1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SSC5D COL12A1

2.68e-03165212e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SSC5D COL12A1

2.68e-031652122026a9a07f4d314cc05c167e491312b373468e46
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SSC5D COL12A1

2.68e-03165212b087771499aeb31cc4a338d2d0a9392a4ec1ac45
Diseasebrain cancer (implicated_via_orthology)

L3MBTL3 NOTCH1

1.13e-0426182DOID:1319 (implicated_via_orthology)
Diseasecholangiocarcinoma (is_marker_for)

MUC16 NOTCH1

6.93e-0464182DOID:4947 (is_marker_for)
Diseasepentachlorophenol measurement

MUC16 EYS

9.00e-0473182EFO_0022071
Diseaseparathion measurement

MUC16 EYS

9.00e-0473182EFO_0022070
Diseasepotassium chromate measurement

MUC16 EYS

9.00e-0473182EFO_0022072
Diseasemercuric chloride measurement

MUC16 EYS

9.00e-0473182EFO_0022068
Diseaseheptachlor epoxide measurement

MUC16 EYS

9.00e-0473182EFO_0022067
Diseasemethoxychlor measurement

MUC16 EYS

9.00e-0473182EFO_0022069
Disease4,6-dinitro-o-cresol measurement

MUC16 EYS

9.00e-0473182EFO_0022053
Disease2,4,5-trichlorophenol measurement

MUC16 EYS

9.00e-0473182EFO_0022052
Diseaseazinphos methyl measurement

MUC16 EYS

9.00e-0473182EFO_0022055
Diseasealdrin measurement

MUC16 EYS

9.00e-0473182EFO_0022054
Diseasedicofol measurement

MUC16 EYS

9.00e-0473182EFO_0022060
Diseasedisulfoton measurement

MUC16 EYS

9.00e-0473182EFO_0022062
Diseasedieldrin measurement

MUC16 EYS

9.00e-0473182EFO_0022061
Diseaseendrin measurement

MUC16 EYS

9.00e-0473182EFO_0022064
Diseaseendosulfan measurement

MUC16 EYS

9.00e-0473182EFO_0022063
Diseaseheptachlor measurement

MUC16 EYS

9.00e-0473182EFO_0022066
Diseaseethion measurement

MUC16 EYS

9.00e-0473182EFO_0022065
Diseasechlorpyrifos measurement

MUC16 EYS

9.00e-0473182EFO_0022057
Diseasecadmium chloride measurement

MUC16 EYS

9.00e-0473182EFO_0022056
Diseasediazinon measurement

MUC16 EYS

9.00e-0473182EFO_0022059
Diseasedibutyl phthalate measurement

MUC16 EYS

9.00e-0473182EFO_0022058
Diseaseenvironmental exposure measurement

MUC16 EYS

9.00e-0473182EFO_0008360
DiseaseDDT metabolite measurement

MUC16 EYS

9.25e-0474182EFO_0007886
Diseaseeye color

MUC16 EYS

1.36e-0390182EFO_0003949
DiseaseAlzheimer disease, APOE carrier status

L3MBTL3 NOTCH1

1.61e-0398182EFO_0007659, MONDO_0004975
Diseaseblood cobalt measurement

MUC16 EYS

1.71e-03101182EFO_0007577
Diseaseblood nickel measurement

MUC16 EYS

2.40e-03120182EFO_0007583
Diseasecoronary artery calcification

FSIP2 EYS NOTCH1

2.42e-03450183EFO_0004723
Diseasemelanoma

EYS COL12A1

2.65e-03126182EFO_0000756
DiseaseMalignant neoplasm of breast

L3MBTL3 TACC2 NOTCH1 KEAP1

3.55e-031074184C0006142

Protein segments in the cluster

PeptideGeneStartEntry
DTVCEDMTFSTWTPP

ADGRE2

256

Q9UHX3
SSEGSMWATVPSSPT

RIMBP3B

786

A6NNM3
SSEGSMWATVPSSPT

RIMBP3C

786

A6NJZ7
TTTWMVPTAQEAPTS

L3MBTL3

61

Q96JM7
VSWMTTPPVEETSSV

MUC16

5321

Q8WXI7
DVSWMTTPPVEETSS

MUC16

5616

Q8WXI7
IRTVPSSEPDTMASW

MUC16

11676

Q8WXI7
DWSEGVSSPPTSMQS

NOTCH1

2531

P46531
VDTMWTSVSPSVAAP

EYS

2086

Q5T1H1
VESMAWTTPDPTSPD

HPS4

301

Q9NQG7
TPKTMPETASSSWEE

FSIP2

6756

Q5CZC0
NLWISDTMSSTEPPS

GTPBP10

361

A4D1E9
SDPTMSSFRVTWEPA

COL12A1

1096

Q99715
WVSSSEPLDTSVESM

FAM172A

346

Q8WUF8
PVPSVTPSTWMATTE

CEACAM19

211

Q7Z692
PDTDTWSEVTRMTSG

KEAP1

586

Q14145
SMSTSAEWSSPVAPT

KIAA1210

1066

Q9ULL0
GISSWPEMEVSVETS

SPHKAP

466

Q2M3C7
SSEGSMWATVPSSPT

RIMBP3

786

Q9UFD9
AEMAWTTSMPAPTTT

SSC5D

1546

A1L4H1
MDPTTPAWGTESTTV

MRGPRX2

1

Q96LB1
PQDSTMDWSTIVVDP

TIE1

486

P35590
SDTPTSSPTDMVWES

TACC2

911

O95359
SSPTDMVWESSLTEE

TACC2

916

O95359
EPWEMTSEMTRSPFS

ZNF471

71

Q9BX82