Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	chromatin remodeling	SETD1A NRDE2 ARID4B BABAM1 CTCF SETD5 KAT6A NAP1L1 SHPRH SMARCA4 KAT6B DICER1 MBD3	1.50e-05	741	88	13	GO:0006338
GeneOntologyBiologicalProcess	chromatin organization	SETD1A NRDE2 ARID4B BABAM1 CTCF SETD5 KAT6A NAP1L1 SHPRH AEBP2 SMARCA4 KAT6B DICER1 MBD3	2.48e-05	896	88	14	GO:0006325
GeneOntologyBiologicalProcess	actin rod assembly	HSP90B1 HSP90B2P	5.38e-05	3	88	2	GO:0031247
GeneOntologyBiologicalProcess	protein-DNA complex organization	SETD1A NRDE2 ARID4B BABAM1 CTCF SETD5 KAT6A NAP1L1 SHPRH AEBP2 SMARCA4 KAT6B DICER1 MBD3	8.07e-05	999	88	14	GO:0071824
GeneOntologyCellularComponent	nuclear protein-containing complex	TRERF1 SETD1A GTF2F1 ARID4B BABAM1 SETD5 CLNS1A ZCRB1 AEBP2 SMARCA4 ASCC2 ACIN1 TFIP11 MPND MBD3 TERF2IP	2.09e-04	1377	89	16	GO:0140513
GeneOntologyCellularComponent	BRISC complex	BABAM1 MPND	2.66e-04	6	89	2	GO:0070552
GeneOntologyCellularComponent	MOZ/MORF histone acetyltransferase complex	KAT6A KAT6B	3.71e-04	7	89	2	GO:0070776
GeneOntologyCellularComponent	chromatin	SOX12 SETD1A RHOXF2B ARID4B PRM3 SETD5 RHOXF2 KAT6A NAP1L1 SHPRH AEBP2 SMARCA4 KAT6B RFX1 MBD3 TBX2	4.69e-04	1480	89	16	GO:0000785
GeneOntologyCellularComponent	histone deacetylase complex	TRERF1 ARID4B SETD5 MBD3	4.78e-04	85	89	4	GO:0000118
GeneOntologyCellularComponent	H3 histone acetyltransferase complex	KAT6A KAT6B	4.94e-04	8	89	2	GO:0070775
GeneOntologyCellularComponent	BRCA1-A complex	BABAM1 MPND	4.94e-04	8	89	2	GO:0070531
GeneOntologyCellularComponent	nuclear speck	SETD1A NRDE2 KAT6A ASCC2 ACIN1 TFIP11 PPP4R3A NCBP3	5.03e-04	431	89	8	GO:0016607
GeneOntologyCellularComponent	endoplasmic reticulum chaperone complex	HSP90B1 HSP90B2P	1.36e-03	13	89	2	GO:0034663
GeneOntologyCellularComponent	nuclear body	SETD1A NRDE2 BABAM1 SUGP2 KAT6A ASCC2 ACIN1 TFIP11 TERF2IP PPP4R3A NCBP3	1.55e-03	903	89	11	GO:0016604
GeneOntologyCellularComponent	respiratory chain complex III	UQCRH UQCRHL	1.82e-03	15	89	2	GO:0045275
Domain	UCR_hinge	UQCRH UQCRHL	2.14e-05	2	87	2	PF02320
Domain	Ubol_cytC_Rdtase_hinge_dom	UQCRH UQCRHL	2.14e-05	2	87	2	IPR023184
Domain	-	UQCRH UQCRHL	2.14e-05	2	87	2	1.10.287.20
Domain	Cyt_b-c1_6	UQCRH UQCRHL	2.14e-05	2	87	2	IPR003422
Domain	H15	KAT6A SHPRH KAT6B	2.70e-05	13	87	3	SM00526
Domain	H15	KAT6A SHPRH KAT6B	2.70e-05	13	87	3	PS51504
Domain	Histone_H1/H5_H15	KAT6A SHPRH KAT6B	3.42e-05	14	87	3	IPR005818
Domain	PHD	PHF23 KAT6A SHPRH DIDO1 KAT6B	5.96e-05	89	87	5	SM00249
Domain	Znf_PHD	PHF23 KAT6A SHPRH DIDO1 KAT6B	6.63e-05	91	87	5	IPR001965
Domain	ZF_PHD_2	PHF23 KAT6A SHPRH DIDO1 KAT6B	8.14e-05	95	87	5	PS50016
Domain	ZF_PHD_1	PHF23 KAT6A SHPRH DIDO1 KAT6B	8.55e-05	96	87	5	PS01359
Domain	MOZ_SAS	KAT6A KAT6B	2.13e-04	5	87	2	PF01853
Domain	HAT_MYST-type	KAT6A KAT6B	2.13e-04	5	87	2	IPR002717
Domain	MYST_HAT	KAT6A KAT6B	2.13e-04	5	87	2	PS51726
Domain	PHD	PHF23 KAT6A DIDO1 KAT6B	4.15e-04	75	87	4	PF00628
Domain	Znf_PHD-finger	PHF23 KAT6A DIDO1 KAT6B	5.06e-04	79	87	4	IPR019787
Domain	-	GTF2F1 KAT6A RAPGEF4 SHPRH KAT6B RFX1	5.43e-04	218	87	6	1.10.10.10
Domain	Znf_FYVE_PHD	PHF23 KAT6A SHPRH DIDO1 KAT6B	6.21e-04	147	87	5	IPR011011
Domain	WHTH_DNA-bd_dom	GTF2F1 KAT6A RAPGEF4 SHPRH KAT6B RFX1	9.36e-04	242	87	6	IPR011991
Domain	Linker_histone	SHPRH KAT6B	1.62e-03	13	87	2	PF00538
Domain	G_patch	SUGP2 TFIP11	5.09e-03	23	87	2	SM00443
Domain	G_patch_dom	SUGP2 TFIP11	5.09e-03	23	87	2	IPR000467
Domain	G_PATCH	SUGP2 TFIP11	5.09e-03	23	87	2	PS50174
Domain	G-patch	SUGP2 TFIP11	5.09e-03	23	87	2	PF01585
Domain	-	PEG10 ZCRB1	6.48e-03	26	87	2	4.10.60.10
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	SETD1A ARID4B KAT6A AEBP2 SMARCA4 KAT6B MBD3	1.24e-05	175	63	7	MM14941
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	SETD1A GSE1 SBNO1 PEG10 ACIN1 DIDO1 TFIP11 KAT6B RFX1 NOP2 MBD3 NCBP3	7.86e-11	341	89	12	32971831
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MICALL1 TRERF1 ARID4B GSE1 SUGP2 SMARCA4 ACIN1 DIDO1 TFIP11 KAT6B RFX1 NOP2 TERF2IP PPP4R3A	1.06e-08	774	89	14	15302935
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	GTF2F1 SALL2 GSE1 SUGP2 SBNO1 SMARCA4 DIDO1 TFIP11 MBD3 GTF3C5	1.74e-08	339	89	10	30415952
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TRERF1 ARHGDIB BTF3L4 GTF2F1 GSE1 SUGP2 INPP5D EIF2S2 ZNF316 NAP1L1 SMARCA4 DIDO1 RFX1 NOP2 MBD3 PPP4R3A	1.89e-08	1103	89	16	34189442
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	BTF3L4 GTF2F1 SUGP2 ZNF532 SBNO1 PHF23 CTCF EIF2S2 NAP1L1 SMARCA4 ACIN1 DIDO1 MBD3 GTF3C5 PPP4R3A	4.30e-08	1014	89	15	32416067
Pubmed	The functional interactome landscape of the human histone deacetylase family.	TRERF1 ZNF326 ARID4B GSE1 ACIN1 TFIP11 NOP2 DICER1 MBD3	5.93e-08	289	89	9	23752268
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	NEFM NRDE2 HSP90B1 BTF3L4 ZNF326 SUGP2 ZNF532 EIF2S2 SMARCA4 ACIN1 DIDO1 TFIP11 MPND MBD3 GTF3C5	9.99e-08	1082	89	15	38697112
Pubmed	Human transcription factor protein interaction networks.	TRERF1 SETD1A ZNF326 SALL2 ARID4B GSE1 SUGP2 PHF23 CTCF PEG10 NFKBIB SMARCA4 DIDO1 TFIP11 PRKCSH RFX1 NOP2	1.13e-07	1429	89	17	35140242
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	TRERF1 GSE1 CTCF CLNS1A NAP1L1 ACIN1 NOP2 DICER1 MBD3 GTF3C5 PPP4R3A TBX2	1.14e-07	655	89	12	35819319
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ZNF326 ARID4B SUGP2 CTCF EIF2S2 SMARCA4 ACIN1 DIDO1 TFIP11 UQCRH RFX1 NOP2 MBD3 NCBP3	1.41e-07	954	89	14	36373674
Pubmed	Human CCAAT/enhancer-binding protein β interacts with chromatin remodeling complexes of the imitation switch subfamily.	NAP1L1 SHPRH SMARCA4 RFX1 TERF2IP	1.54e-07	48	89	5	22242598
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	NRDE2 BTF3L4 GTF2F1 ZNF326 BABAM1 TOMM22 CTCF SETD5 EIF2S2 NAP1L1 ASCC2 DIDO1 TFIP11 DICER1 MBD3 TERF2IP TBX2	2.19e-07	1497	89	17	31527615
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	SETD1A CRYBG2 NAP1L1 AEBP2 SMARCA4 ACIN1 MBD3 GTF3C5 TERF2IP NCBP3	3.55e-07	469	89	10	27634302
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	NRDE2 ZNF326 SUGP2 CTCF PEG10 NAP1L1 SMARCA4 ASCC2 ACIN1 DIDO1 TFIP11 NOP2 DICER1 MBD3 GTF3C5 NCBP3	3.65e-07	1371	89	16	36244648
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ARID4B SBNO1 KAT6A SHPRH SMARCA4 DIDO1 RFX1 NOP2 MBD3 GTF3C5 NCBP3	4.54e-07	608	89	11	36089195
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	ZNF326 ARID4B SUGP2 KAT6A EIF2S2 SMARCA4 ACIN1 DIDO1 NOP2 GTF3C5 TERF2IP NCBP3	5.47e-07	759	89	12	35915203
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	SETD1A GTF2F1 SMARCA4 DIDO1 MBD3 PPP4R3A	1.31e-06	134	89	6	25452129
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NEFM SETD1A SUGP2 NAP1L1 SMARCA4 ACIN1 DIDO1 TFIP11 RFX1 GTF3C5	1.47e-06	549	89	10	38280479
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	NEFM ZNF326 SALL2 ARID4B GSE1 SUGP2 PHF23 EIF2S2 SMARCA4 RFX1 GTF3C5 TBX2	1.94e-06	857	89	12	25609649
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	ZNF326 ARID4B CTCF CLNS1A SMARCA4 ACIN1 RFX1 MBD3 GTF3C5 TBX2	2.52e-06	583	89	10	29844126
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	ZNF326 SUGP2 CTCF NAP1L1 SMARCA4 TFIP11 DICER1	3.91e-06	251	89	7	28077445
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	HSP90B1 BTF3L4 GSE1 SUGP2 CTCF NAP1L1 SMARCA4 ACIN1 DIDO1 TFIP11 NOP2 PPP4R3A	4.67e-06	934	89	12	33916271
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FOCAD NEFM HSP90B1 ZNF532 SBNO1 PEG10 MRFAP1 RAPGEF4 NGEF NAP1L1 SMARCA4 TFIP11 IFT122 TERF2IP	4.73e-06	1285	89	14	35914814
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	NEFM ARHGDIB BABAM1 PEG10 MRFAP1 KAT6A ASCC2 CNKSR2 PRKCSH MPND UQCRH DICER1 TGOLN2 NCBP3	5.07e-06	1293	89	14	15342556
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	ZNF326 INPP5D EIF2S2 SMARCA4 ACIN1 TFIP11 GTF3C5 NCBP3	5.08e-06	370	89	8	22922362
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SALL2 ARID4B GSE1 SUGP2 CTCF SETD5 KAT6A ZNF316 SMARCA4 KAT6B DICER1 MBD3 TBX2	5.24e-06	1116	89	13	31753913
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TRERF1 NEFM CTCF RAPGEF4 NGEF SMARCA4 PAK3 DIDO1 CNKSR2 NOP2 MBD3 WNK2	6.36e-06	963	89	12	28671696
Pubmed	gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	19965672
Pubmed	Essential role of the molecular chaperone gp96 in regulating melanogenesis.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	24024552
Pubmed	Evidence that glycoprotein 96 (B2), a stress protein, functions as a Th2-specific costimulatory molecule.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	12244140
Pubmed	Glucose-regulated protein 94/glycoprotein 96 elicits bystander activation of CD4+ T cell Th1 cytokine production in vivo.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	15034032
Pubmed	Knockout of the Complex III subunit Uqcrh causes bioenergetic impairment and cardiac contractile dysfunction.	UQCRH UQCRHL	6.48e-06	2	89	2	36565314
Pubmed	Cross-presentation of glycoprotein 96-associated antigens on major histocompatibility complex class I molecules requires receptor-mediated endocytosis.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	10839811
Pubmed	Down-regulation of gp96 by Orientia tsutsugamushi.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	15107540
Pubmed	Cloning and characterization of Ehox, a novel homeobox gene essential for embryonic stem cell differentiation.	RHOXF2B RHOXF2	6.48e-06	2	89	2	12087094
Pubmed	Mapping of the genes for human endoplasmic reticular heat shock protein gp96/grp94.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	8460400
Pubmed	An essential role for ATP binding and hydrolysis in the chaperone activity of GRP94 in cells.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	19553200
Pubmed	Oocyte-targeted deletion reveals that hsp90b1 is needed for the completion of first mitosis in mouse zygotes.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	21358806
Pubmed	Radicicol-sensitive peptide binding to the N-terminal portion of GRP94.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	12189140
Pubmed	Amino acid copolymers that alleviate experimental autoimmune encephalomyelitis in vivo interact with heparan sulfates and glycoprotein 96 in APCs.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	23740953
Pubmed	GP96 Drives Exacerbation of Secondary Bacterial Pneumonia following Influenza A Virus Infection.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	34061598
Pubmed	Glucose regulated protein 94 is required for muscle differentiation through its control of the autocrine production of insulin-like growth factors.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	19914304
Pubmed	Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	23859598
Pubmed	HSP100, a 100-kDa heat shock protein, is a Ca2+-calmodulin-regulated actin-binding protein.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	2768254
Pubmed	GRP94 promotes muscle differentiation by inhibiting the PI3K/AKT/mTOR signaling pathway.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	31025379
Pubmed	Chaperone gp96 mediates ER-α36 cell membrane expression.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	26396174
Pubmed	Type 2 dendritic cells mediate control of cytotoxic T cell resistant tumors.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	34283809
Pubmed	Isolation and identification of partial cDNA clones for endoplasmin, the major glycoprotein of mammalian endoplasmic reticulum.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	3612811
Pubmed	The peptide-binding activity of GRP94 is regulated by calcium.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	17411420
Pubmed	Cell surface targeting of heat shock protein gp96 induces dendritic cell maturation and antitumor immunity.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	11739487
Pubmed	5'-structural analysis of genes encoding polymorphic antigens of chemically induced tumors.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	2438686
Pubmed	Cutting Edge: Targeting Thrombocytes to Rewire Anticancer Immunity in the Tumor Microenvironment and Potentiate Efficacy of PD-1 Blockade.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	31358658
Pubmed	Interaction of Toll-Like Receptors with the Molecular Chaperone Gp96 Is Essential for Its Activation of Cytotoxic T Lymphocyte Response.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	27183126
Pubmed	Combination of direct intratumoral administration of dendritic cells and irradiation induces strong systemic antitumor effect mediated by GRP94/gp96 against squamous cell carcinoma in mice.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	17671676
Pubmed	Treg suppress CTL responses upon immunization with HSP gp96.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	19839010
Pubmed	Regulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Disease.	KAT6A KAT6B	6.48e-06	2	89	2	27185879
Pubmed	GRP94 Is Involved in the Lipid Phenotype of Brain Metastatic Cells.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	31395819
Pubmed	Immunolocalization and heart levels of GRP94 in the mouse during post-implantation development.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	9363855
Pubmed	Limitation of individual folding resources in the ER leads to outcomes distinct from the unfolded protein response.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	22854046
Pubmed	GRP94 (gp96) and GRP94 N-terminal geldanamycin binding domain elicit tissue nonrestricted tumor suppression.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	12461080
Pubmed	Endoplasmic reticulum resident heat shock protein-gp96 as morphogenetic and immunoregulatory factor in syngeneic pregnancy.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	23553495
Pubmed	Deletion of muscle GRP94 impairs both muscle and body growth by inhibiting local IGF production.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	22649033
Pubmed	Glucose-regulated protein (GRP94 and GRP78) genes share common regulatory domains and are coordinately regulated by common trans-acting factors.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	2546060
Pubmed	The endoplasmic reticulum chaperone BiP is a closure-accelerating cochaperone of Grp94.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	35078937
Pubmed	The molecular chaperone gp96/GRP94 interacts with Toll-like receptors and integrins via its C-terminal hydrophobic domain.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	22223641
Pubmed	Induction of regulatory T cells by high-dose gp96 suppresses murine liver immune hyperactivation.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	23874845
Pubmed	GRP94/gp96 elicits ERK activation in murine macrophages. A role for endotoxin contamination in NF-kappa B activation and nitric oxide production.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	12805368
Pubmed	Chromosomal assignment of the gene encoding the mouse tumor rejection antigen gp96.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	3410508
Pubmed	Glycoprotein (GP)96 Is Essential for Maintaining Intestinal Epithelial Architecture by Supporting Its Self-Renewal Capacity.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	36516930
Pubmed	Rhox homeobox gene cluster: recent duplication of three family members.	RHOXF2B RHOXF2	6.48e-06	2	89	2	16496311
Pubmed	Exploring the Interaction between the SWI/SNF Chromatin Remodeling Complex and the Zinc Finger Factor CTCF.	CTCF SMARCA4	6.48e-06	2	89	2	33255744
Pubmed	Phylogenetic conservation of the molecular and immunological properties of the chaperones gp96 and hsp70.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	11265634
Pubmed	ERα status of invasive ductal breast carcinoma as a result of regulatory interactions between lysine deacetylases KAT6A and KAT6B.	KAT6A KAT6B	6.48e-06	2	89	2	39505971
Pubmed	Characterising a homozygous two-exon deletion in UQCRH: comparing human and mouse phenotypes.	UQCRH UQCRHL	6.48e-06	2	89	2	34750991
Pubmed	HSP90β promotes osteoclastogenesis by dual-activation of cholesterol synthesis and NF-κB signaling.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	36198833
Pubmed	gp96 expression in neutrophils is critical for the onset of Escherichia coli K1 (RS218) meningitis.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	22109526
Pubmed	Glycoprotein 96 can chaperone both MHC class I- and class II-restricted epitopes for in vivo presentation, but selectively primes CD8+ T cell effector function.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	15128793
Pubmed	The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	21647226
Pubmed	Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	30670477
Pubmed	Chaperone gp96-independent inhibition of endotoxin response by chaperone-based peptide inhibitors.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	22532561
Pubmed	gp96 is a human colonocyte plasma membrane binding protein for Clostridium difficile toxin A.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	18411291
Pubmed	Targeted deletion of ER chaperone GRP94 in the liver results in injury, repopulation of GRP94-positive hepatocytes, and spontaneous hepatocellular carcinoma development in aged mice.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	25220589
Pubmed	Decreased adhesiveness, resistance to anoikis and suppression of GRP94 are integral to the survival of circulating tumor cells in prostate cancer.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	18340425
Pubmed	Identification of a tandem duplicated array in the Rhox alpha locus on mouse chromosome X.	RHOXF2B RHOXF2	6.48e-06	2	89	2	16465597
Pubmed	The heat shock protein Gp96 binds to human neutrophils and monocytes and stimulates effector functions.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	12446445
Pubmed	Regulation of dendritic cell function improves survival in experimental sepsis through immune chaperone.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	31018807
Pubmed	Hsp90β1 knockout targeted to male germline: a mouse model for globozoospermia.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	21208614
Pubmed	Identification of gp96 as a novel target for treatment of autoimmune disease in mice.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	20352117
Pubmed	Heat-Shock Protein gp96 Enhances T Cell Responses and Protective Potential to Bacillus Calmette-Guérin Vaccine.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	27417661
Pubmed	Proteomic plasma membrane profiling reveals an essential role for gp96 in the cell surface expression of LDLR family members, including the LDL receptor and LRP6.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	22292497
Pubmed	Gp96 deficiency affects TLR4 functionality and impairs ERK and p38 phosphorylation.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	29447283
Pubmed	LyGDI, a novel SHIP-interacting protein, is a negative regulator of FcγR-mediated phagocytosis.	ARHGDIB INPP5D	6.48e-06	2	89	2	21695085
Pubmed	Cloning and characterization of the 5'-flanking region of the Ehox gene.	RHOXF2B RHOXF2	6.48e-06	2	89	2	16414020
Pubmed	Analysis of the structure and synthesis of GRP94, an abundant stress protein of the endoplasmic reticulum.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	8179819
Pubmed	Visualization of conformational transition of GRP94 in solution.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	37949474
Pubmed	The double PHD finger domain of MOZ/MYST3 induces α-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.	KAT6A KAT6B	6.48e-06	2	89	2	24150941
Pubmed	Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor.	HSP90B1 HSP90B2P	6.48e-06	2	89	2	22876182
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	GTF2F1 ZNF326 SUGP2 PEG10 ZCRB1 EIF2S2 NAP1L1 ACIN1 DIDO1 NOP2 NCBP3	6.92e-06	807	89	11	22681889
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SETD1A SALL2 SUGP2 DIDO1 KAT6B	7.38e-06	104	89	5	9205841
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	SUGP2 SMARCA4 ACIN1 DIDO1 TFIP11 NOP2 PPP4R3A	8.55e-06	283	89	7	30585729
Interaction	MEN1 interactions	SETD1A HSP90B1 ZNF326 GSE1 SUGP2 SBNO1 CTCF PEG10 NAP1L1 SMARCA4 ACIN1 DIDO1 TFIP11 KAT6B RFX1 NOP2 MBD3 GTF3C5 NCBP3	9.10e-08	1029	89	19	int:MEN1
Interaction	CHD3 interactions	ZNF326 ARID4B GSE1 SUGP2 SBNO1 KAT6A SHPRH SMARCA4 ASCC2 ACIN1 TFIP11 TNNT1 NOP2 MBD3 TERF2IP NCBP3	1.83e-07	757	89	16	int:CHD3
Interaction	HMGXB4 interactions	HSP90B1 ARID4B STAC3 SHPRH TNNT1 MBD3 TERF2IP	6.81e-07	113	89	7	int:HMGXB4
Interaction	TERF2IP interactions	SETD1A GTF2F1 SALL2 BABAM1 SUGP2 SBNO1 CTCF SMARCA4 DIDO1 MPND RFX1 GTF3C5 TERF2IP	8.89e-07	552	89	13	int:TERF2IP
Interaction	POLR1G interactions	GTF2F1 ARID4B SBNO1 CTCF SKAP1 NFKBIB KAT6A SMARCA4 MPND NOP2 GTF3C5 NCBP3	1.59e-06	489	89	12	int:POLR1G
Interaction	CSNK2A1 interactions	SETD1A HSP90B1 BTF3L4 GTF2F1 ARID4B CLNS1A NFKBIB STAC3 KAT6A EIF2S2 NAP1L1 SMARCA4 ACIN1 CNKSR2 MBD3 GTF3C5	3.94e-06	956	89	16	int:CSNK2A1
Interaction	ZBTB2 interactions	FOCAD BTF3L4 ZNF326 SBNO1 CTCF KAT6A NAP1L1 ACIN1 NOP2 MBD3 TERF2IP	4.65e-06	450	89	11	int:ZBTB2
Interaction	RBBP4 interactions	SETD1A ARID4B GSE1 ZNF532 PHF23 CTCF NAP1L1 SHPRH AEBP2 SMARCA4 MBD3 TGOLN2	8.04e-06	573	89	12	int:RBBP4
Interaction	KPNA3 interactions	HSP90B1 ZNF326 CLGN CTCF UVSSA NFKBIB SMARCA4 ACIN1	1.41e-05	248	89	8	int:KPNA3
Interaction	HECTD1 interactions	BTF3L4 ZNF326 ARID4B SUGP2 KAT6A EIF2S2 NAP1L1 SMARCA4 ACIN1 DIDO1 NOP2 GTF3C5 TERF2IP TGOLN2 NCBP3	2.47e-05	984	89	15	int:HECTD1
Interaction	SUZ12 interactions	SETD1A ZNF326 CTCF EIF2S2 SHPRH AEBP2 SMARCA4 ACIN1 NOP2 MBD3 TERF2IP NCBP3	2.57e-05	644	89	12	int:SUZ12
Interaction	CEBPA interactions	TRERF1 ARHGDIB BTF3L4 GTF2F1 GSE1 SUGP2 INPP5D EIF2S2 ZNF316 NAP1L1 SMARCA4 ACIN1 DIDO1 RFX1 NOP2 MBD3 PPP4R3A	2.73e-05	1245	89	17	int:CEBPA
Interaction	KDM5C interactions	ZNF532 CTCF MRFAP1 SMARCA4 GTF3C5 TERF2IP	3.51e-05	139	89	6	int:KDM5C
Interaction	H3C1 interactions	SETD1A BTF3L4 GTF2F1 ARID4B CTCF KAT6A NAP1L1 SHPRH SMARCA4 DIDO1 KAT6B NOP2 MBD3 GTF3C5	3.87e-05	901	89	14	int:H3C1
Interaction	MECP2 interactions	NEFM NRDE2 HSP90B1 BTF3L4 ZNF326 SUGP2 ZNF532 EIF2S2 SMARCA4 ACIN1 DIDO1 TFIP11 MPND RFX1 NOP2 MBD3 GTF3C5	4.15e-05	1287	89	17	int:MECP2
Interaction	SSRP1 interactions	ZNF326 SUGP2 SBNO1 SETD5 KAT6A NAP1L1 SMARCA4 ACIN1 DIDO1 NOP2 MBD3 TERF2IP	4.68e-05	685	89	12	int:SSRP1
Interaction	SIN3B interactions	ARID4B PHF23 MRFAP1 SHPRH SMARCA4 MBD3	4.80e-05	147	89	6	int:SIN3B
Interaction	RNF113A interactions	TRERF1 GSE1 CTCF CLNS1A NAP1L1 ACIN1 NOP2 DICER1 MBD3 GTF3C5 PPP4R3A TBX2	5.16e-05	692	89	12	int:RNF113A
Interaction	CDK8 interactions	GTF2F1 ARID4B SUGP2 SBNO1 SMARCA4 GTF3C5 PPP4R3A	5.74e-05	222	89	7	int:CDK8
Interaction	CHD4 interactions	SETD1A ZNF326 GSE1 SUGP2 KAT6A SHPRH SMARCA4 ACIN1 TFIP11 PRKCSH NOP2 MBD3 PPP4R3A NCBP3	5.98e-05	938	89	14	int:CHD4
Interaction	KPNA4 interactions	HSP90B1 CLGN ZNF532 CTCF MBD3 TERF2IP NCBP3	6.24e-05	225	89	7	int:KPNA4
Interaction	RBBP7 interactions	SALL2 ARID4B GSE1 PHF23 CTCF SHPRH AEBP2 SMARCA4 MBD3 PPP4R3A	7.98e-05	507	89	10	int:RBBP7
Interaction	NUP43 interactions	SETD1A SALL2 ARID4B GSE1 ZNF532 CTCF ZNF316 NGEF SMARCA4 ACIN1 NCBP3	9.52e-05	625	89	11	int:NUP43
Interaction	KPNA2 interactions	SETD1A GTF2F1 CTCF NFKBIB KAT6A NGEF SMARCA4 PRKCSH MBD3 PPP4R3A	9.67e-05	519	89	10	int:KPNA2
Interaction	HP1BP3 interactions	ZNF326 CTCF KAT6A ZCRB1 NOP2 TERF2IP TGOLN2 NCBP3	1.04e-04	329	89	8	int:HP1BP3
Interaction	SNX12 interactions	PEG10 CLNS1A SSTR3 PPP4R3A	1.10e-04	56	89	4	int:SNX12
Interaction	SNRNP40 interactions	GTF2F1 ZNF326 GSE1 SUGP2 ZNF532 CTCF KAT6A ZNF316 SMARCA4 ACIN1 TFIP11	1.13e-04	637	89	11	int:SNRNP40
Interaction	PHF1 interactions	ARID4B SHPRH AEBP2 TFIP11 DICER1 MBD3	1.15e-04	172	89	6	int:PHF1
Interaction	SMC5 interactions	ZNF326 ARID4B SUGP2 CTCF EIF2S2 SMARCA4 ACIN1 DIDO1 TFIP11 UQCRH RFX1 NOP2 MBD3 NCBP3	1.18e-04	1000	89	14	int:SMC5
Interaction	ACRBP interactions	BTF3L4 SBNO1 MBD3	1.21e-04	22	89	3	int:ACRBP
Interaction	FOXP3 interactions	ZNF326 SUGP2 INPP5D EIF2S2 SMARCA4 ACIN1 TFIP11 GTF3C5 NCBP3	1.23e-04	432	89	9	int:FOXP3
Interaction	LDOC1 interactions	SETD5 PEG10 AEBP2 TNNT1 MBD3	1.51e-04	114	89	5	int:LDOC1
Interaction	ETS2 interactions	FOCAD SMARCA4 GTF3C5 TERF2IP	1.53e-04	61	89	4	int:ETS2
Interaction	CIC interactions	ZNF326 ARID4B CTCF CLNS1A SMARCA4 ACIN1 RFX1 MBD3 GTF3C5 TERF2IP TBX2	1.82e-04	673	89	11	int:CIC
Interaction	PYHIN1 interactions	ZNF326 SUGP2 CTCF NAP1L1 SMARCA4 TFIP11 RFX1 DICER1	1.85e-04	358	89	8	int:PYHIN1
Interaction	NFIA interactions	ZNF326 ARID4B GSE1 ACIN1 NOP2 TERF2IP	1.86e-04	188	89	6	int:NFIA
Interaction	SMARCA1 interactions	SETD1A ARID4B SHPRH SMARCA4 MBD3 TERF2IP	1.86e-04	188	89	6	int:SMARCA1
Interaction	RAD18 interactions	SETD1A CTCF EIF2S2 NAP1L1 SHPRH SMARCA4 ACIN1 TFIP11 TERF2IP	1.87e-04	457	89	9	int:RAD18
Interaction	UQCRHL interactions	UQCRH UQCRHL	1.91e-04	5	89	2	int:UQCRHL
Interaction	GCNA interactions	HSP90B1 HSP90B2P	1.91e-04	5	89	2	int:GCNA
Interaction	RPL31 interactions	BTF3L4 GTF2F1 ARL10 CTCF UVSSA KAT6A ZCRB1 NAP1L1 ACIN1 NOP2 NCBP3	1.99e-04	680	89	11	int:RPL31
Interaction	CTCF interactions	SETD1A ZNF326 CTCF KAT6A ZCRB1 EIF2S2 SMARCA4 ACIN1 TERF2IP	2.00e-04	461	89	9	int:CTCF
Interaction	ATP1B2 interactions	HSP90B1 CLGN SSTR3	2.26e-04	27	89	3	int:ATP1B2
Interaction	H2BC21 interactions	TMC1 ARID4B KAT6A NAP1L1 SHPRH SMARCA4 DIDO1 KAT6B NOP2 MBD3 GTF3C5	2.43e-04	696	89	11	int:H2BC21
Interaction	TOP1 interactions	GTF2F1 ZNF326 ARID4B KAT6A SMARCA4 ACIN1 DIDO1 TNNT1 NOP2 GTF3C5 TERF2IP	2.43e-04	696	89	11	int:TOP1
Interaction	SNRPF interactions	ZNF326 CLNS1A ZCRB1 ACIN1 DIDO1 TFIP11 TERF2IP PPP4R3A	3.03e-04	385	89	8	int:SNRPF
Interaction	ARMCX3 interactions	ARL10 TOMM22 ACIN1 PRKCSH UQCRH	3.09e-04	133	89	5	int:ARMCX3
Interaction	BCL11B interactions	ARID4B SHPRH SMARCA4 MBD3	3.23e-04	74	89	4	int:BCL11B
Interaction	CUL4B interactions	NEFM HSP90B1 SALL2 ARID4B MRFAP1 UVSSA NAP1L1 SMARCA4 IFT122 MBD3 NCBP3	3.57e-04	728	89	11	int:CUL4B
Interaction	SENP3 interactions	NEFM HSP90B1 ARL10 SUGP2 KAT6A ACIN1 NCBP3	3.74e-04	301	89	7	int:SENP3
Interaction	ARSA interactions	HSP90B1 CLGN RHOXF2 TGOLN2	3.76e-04	77	89	4	int:ARSA
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	GTF2F1 BABAM1 SUGP2 SMARCA4 PLPPR3 PRKCSH MPND RFX1 MBD3	2.52e-05	797	89	9	chr19p13
Cytoband	Xp22.12	CNKSR2 KLHL34	1.03e-04	8	89	2	Xp22.12
Cytoband	19p13.3	GTF2F1 PLPPR3 MPND MBD3	1.20e-03	237	89	4	19p13.3
Cytoband	12p12.3	ARHGDIB AEBP2	1.77e-03	32	89	2	12p12.3
Cytoband	22q12.1	ASCC2 TFIP11	1.77e-03	32	89	2	22q12.1
Cytoband	11p15	IRAG1 NLRP6	3.19e-03	43	89	2	11p15
GeneFamily	PHD finger proteins	PHF23 KAT6A SHPRH DIDO1 KAT6B	1.20e-05	90	60	5	88
GeneFamily	Zinc fingers C2HC-type\|PHD finger proteins\|Lysine acetyltransferases	KAT6A KAT6B	1.26e-03	16	60	2	66
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	KAT6A KAT6B	1.43e-03	17	60	2	486
GeneFamily	G-patch domain containing\|Minor histocompatibility antigens	SUGP2 TFIP11	2.40e-03	22	60	2	579
GeneFamily	General transcription factors\|Xeroderma pigmentosum complementation groups\|DNA helicases\|ERCC excision repair associated	GTF2F1 GTF3C5	3.09e-03	25	60	2	565
Coexpression	GSE12366_GC_BCELL_VS_PLASMA_CELL_UP	ARID4B INPP5D NAP1L1 AEBP2 SMARCA4 NOP2 NCBP3	4.98e-06	197	89	7	M3166
Coexpression	GSE17721_LPS_VS_PAM3CSK4_6H_BMDC_DN	ARHGDIB ZNF326 CLNS1A ASCC2 NOP2 MBD3 UQCRHL	5.33e-06	199	89	7	M3919
Coexpression	GSE46143_CTRL_VS_LMP2A_TRANSDUCED_CD10_POS_GC_BCELL_UP	ARL10 NFKBIB TFIP11 PRKCSH SSTR3 MBD3 WNK2	5.50e-06	200	89	7	M9771
Coexpression	TABULA_MURIS_SENIS_MARROW_MATURE_ALPHA_BETA_T_CELL_AGEING	ARHGDIB HSP90B1 CRYBG2 HSP90B2P TOMM22 PHF23 SETD5 SKAP1 NFKBIB ZCRB1 EIF2S2	7.22e-06	612	89	11	MM3804
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	MICALL1 SETD1A SUGP2 SETD5 ZNF316 SMARCA4 ACIN1 MBD3	2.01e-05	338	89	8	M17094
Coexpression	GSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_UP	MICALL1 SBNO1 INPP5D TBC1D12 KAT6B NOP2	3.61e-05	181	89	6	M6849
Coexpression	BENPORATH_SOX2_TARGETS	HSP90B1 BTF3L4 ARID4B SUGP2 PHF23 KAT6A ZCRB1 ACIN1 DIDO1 MPND RFX1	3.87e-05	734	89	11	M3835
Coexpression	GSE42021_CD24LO_TREG_VS_CD24LO_TCONV_THYMUS_DN	HSP90B1 GTF2F1 ARL10 TFIP11 PRKCSH MBD3	6.29e-05	200	89	6	M9609
Coexpression	MURARO_PANCREAS_BETA_CELL	NEFM CACNA1D BTF3L4 CLGN GSE1 SBNO1 ZCRB1 NAP1L1 KAT6B DICER1 TERF2IP TGOLN2	8.40e-05	946	89	12	M39169
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	NEFM SOX12 SETD1A GSE1 TMED8 WNK2	3.06e-06	200	89	6	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKRD35 TMC1 SUGP2 PEG10 IRAG1	2.91e-05	178	89	5	63f5880a5b514e20ef2c07a6a9cb8df34e6cede5
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKRD35 TMC1 SUGP2 PEG10 IRAG1	2.91e-05	178	89	5	82c84f8b8a7e6a3d3be3351b348a37143279c100
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKRD35 TMC1 SUGP2 PEG10 IRAG1	2.91e-05	178	89	5	cb91558469ae0748106fb0b6d702edb0ff21a884
ToppCell	RA-17._Lymphocyte\|RA / Chamber and Cluster_Paper	TRERF1 ARHGDIB INPP5D SKAP1 NLRP6	3.23e-05	182	89	5	257a7847917b6ea1d60608183d90300bfd028758
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ARHGDIB VGLL3 IRAG1 TNNT1 TBX2	3.23e-05	182	89	5	da61e7cb2537c567968d8bd8baf537ecdff0ab18
ToppCell	Cerebellum-Endothelial-MURAL\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ARHGDIB VGLL3 IRAG1 TNNT1 TBX2	3.23e-05	182	89	5	b2f03f61aebb5920595fed8b9d6799a09353419b
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	ARID4B PEG10 PAK3 PPP4R3A NCBP3	3.49e-05	185	89	5	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D CLIP3 AEBP1 PAK3 IRAG1	3.87e-05	189	89	5	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	CACNA1D GSE1 UVSSA CNKSR2 TBX2	3.97e-05	190	89	5	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D CLIP3 AEBP1 PAK3 IRAG1	4.07e-05	191	89	5	b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOCAD CACNA1D RAPGEF4 PAK3 CNKSR2	4.60e-05	196	89	5	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOCAD CACNA1D RAPGEF4 PAK3 CNKSR2	4.83e-05	198	89	5	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOCAD CACNA1D RAPGEF4 PAK3 CNKSR2	4.83e-05	198	89	5	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOCAD CACNA1D RAPGEF4 PAK3 CNKSR2	4.83e-05	198	89	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRERF1 ARHGDIB INPP5D SKAP1 NLRP6	4.94e-05	199	89	5	6150b272313d3fbf5ddcb3a8d51862d368220fe2
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CACNA1D VGLL3 AEBP1 CNKSR2 TBX2	5.06e-05	200	89	5	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	FOCAD CACNA1D RAPGEF4 PAK3 CNKSR2	5.06e-05	200	89	5	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-T_reg\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEFM ARHGDIB INPP5D SKAP1 NLRP6	5.06e-05	200	89	5	68589705dbc84482b6c0a1a27dd552492c4e8c3d
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CACNA1D VGLL3 AEBP1 CNKSR2 TBX2	5.06e-05	200	89	5	a510deaada669e690329183e18df02870bd204b3
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate\|6m / Sample Type, Dataset, Time_group, and Cell type.	PEG10 STAC3 NAP1L1 AEBP2 TNNT1	5.06e-05	200	89	5	7c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCell	H1299\|World / Cell line, Condition and Strain	SUGP2 PEG10 MRFAP1 ZCRB1 NAP1L1	5.06e-05	200	89	5	23f08d7cffacfced48785cd3ad230ecadb95713f
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1D VGLL3 AEBP1 CNKSR2 TBX2	5.06e-05	200	89	5	dd4228cbed8a4395166a6332e08d44d88bebe3b9
Disease	male infertility due to globozoospermia (implicated_via_orthology)	HSP90B1 HSP90B2P	7.08e-06	2	79	2	DOID:0112312 (implicated_via_orthology)
Disease	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	SALL2 CTCF SMARCA4	3.93e-04	53	79	3	C1961099
Disease	schizophrenia (implicated_via_orthology)	CACNA1D SETD1A SBNO1	8.17e-04	68	79	3	DOID:5419 (implicated_via_orthology)
Disease	DiGeorge syndrome (implicated_via_orthology)	KAT6A DICER1	1.18e-03	19	79	2	DOID:11198 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VEPPEEADEEEEADE	TBC1D12	46	O60347
EEEEEEKEPEAEPPV	ACIN1	936	Q9UKV3
SEEEEEIEPFPEERE	ARID4B	296	Q4LE39
GRAEPPEEEEEEEEE	AEBP2	31	Q6ZN18
DNEDEEEPAVEIEPE	CTCF	621	P49711
LEPEFEEEEEEEKEE	AEBP1	1121	Q8IUX7
DDDEEDDADEEAPKP	ASCC2	661	Q9H1I8
EEDDEDGEDEEEVPK	GSE1	1106	Q14687
PEEEQEEKEDEDPCS	ANKRD35	281	Q8N283
EDDDEDEEIEEKEKP	DICER1	416	Q9UPY3
EEEKEEEEEEEEPLP	CFAP44	726	Q96MT7
PEEEEEEEEELVDPL	UQCRHL	16	A0A096LP55
PEEEEEEEEELVDPL	UQCRH	16	P07919
EPTEEECEWKPDEED	NAP1L1	126	P55209
EDDDEDEDKEDTLPL	PPP4R3A	811	Q6IN85
EKPEDDLIKPEEEEE	KAT6B	1341	Q8WYB5
DPEDEEDEEPALEEL	ARL10	61	Q8N8L6
LAPPVSEEEDEEEEE	PAK3	181	O75914
EEPDEEPEETAEDKE	HSP90B2P	356	Q58FF3
APEPEEEEEELEEEE	KLHL34	311	Q8N239
EEEEPEEEDDSPRDD	IFT122	231	Q9HBG6
EEEEEEPDPDPEMEH	MBD3	276	O95983
AEEEEEEEDSEEAPP	PRKCSH	326	P14314
PDSDLEKEEEESEED	NFKBIB	181	Q15653
EEEEQKSESPEEPEE	IRAG1	796	Q9Y6F6
KSESPEEPEEVEETE	IRAG1	801	Q9Y6F6
EEPEEVEETEEEEKG	IRAG1	806	Q9Y6F6
PEKAQEEEEEEESTP	EPYC	76	Q99645
VVINPDEDDDEPEED	NRDE2	551	Q9H7Z3
EQVEPTPEDEDDDIE	PEG10	46	Q86TG7
VNVPEEPIEEEEEEE	NCBP3	336	Q53F19
PFEEEEEDKEEEAPA	MICALL1	426	Q8N3F8
EAPEEDEDEAEAEDP	MPND	16	Q8N594
PEPTEDKDLEADEED	EIF2S2	46	P20042
PDAKVEEEPEEEPEE	HSP90B1	751	P14625
EEEPEEEPEETAEDT	HSP90B1	756	P14625
PETETKEPEVEEEEE	KAT6A	1261	Q92794
QELEEPEPEEEEDAA	KAT6A	1291	Q92794
KEPVADEEEEDSDDD	CLNS1A	91	P54105
EEEEEEEEHSAEPRP	BABAM1	11	Q9NWV8
PEPHVEEDDDDELDS	ARHGDIB	6	P52566
KPEDIDEEDDDVPDL	BTF3L4	131	Q96K17
VAFPEKEEDEEEEEE	CA8	11	P35219
PSLEEKEEEEEEEPE	CRYBG2	821	Q8N1P7
LEEEEDDRPYDPEEE	DIDO1	1376	Q9BTC0
EEEEEEEEDEPVPEA	CLIP3	16	Q96DZ5
PSPEEELSEEEEEED	SALL2	756	Q9Y467
VVKEDDEPEEEDEEE	SBNO1	221	A3KN83
DLNEEEEEEEEESKP	PROCA1	171	Q8NCQ7
GEEEEEEEEDEPEVP	CACNA1D	826	Q01668
EDTEEPEEEEEGEEP	NLRP6	601	P59044
PIPEELDDDEDVEDV	FOCAD	736	Q5VW36
EEEEGEEEEKEELPV	PRM3	56	Q9NNZ6
EPEEVEVLEPEEDFE	MRFAP1	11	Q9Y605
DSSEESEEEKPPEED	GTF2F1	306	P35269
SEEEKPPEEDKEEEE	GTF2F1	311	P35269
DDEHEDAPLPTEEEK	RAPGEF4	291	Q8WZA2
EDEDDEDFVEVPEKE	UVSSA	401	Q2YD98
EEAAEEEEEAPEEPE	TNNT1	16	P13805
TVGPPEKTEEEDEEE	SSTR3	341	P32745
LNPLDPDKDEEEEEE	RFX1	916	P22670
EEEEEEEEEEEPASP	NGEF	216	Q8N5V2
EEPPLKEEDEVPDDE	SMARCA4	1286	P51532
VPLEEEDTGDDPEED	INPP5D	101	Q92835
EVDNPEEKPEEEKEE	SETD5	481	Q9C0A6
VLEEDEDDPESEPEG	SHPRH	256	Q149N8
TEEVKEEEEDAQPEP	RHOXF2B	36	P0C7M4
EDEEEEKEVTPESGP	NOP2	186	P46087
TPAEEDEDDPEQEKE	SETD1A	916	O15047
EDDPEPEPEDEETRK	TMC1	51	Q8TDI8
EEESEPEEKSEEEIE	CLGN	551	O14967
VQPPEVEEEEEEEEE	CNKSR2	871	Q8WXI2
EPTEDVEPKEAEDDD	TGOLN2	316	O43493
VEPKEAEDDDTGPEE	TGOLN2	321	O43493
EEFDDDEKIEVDDPP	ZNF532	136	Q9HCE3
EPEDEVEDDPKVTLE	TBX2	96	Q13207
EEEEEEEEEDEGPAP	PLPPR3	451	Q6T4P5
PSEDEEPEEEEEEAA	SOX12	221	O15370
ESPEVMPEEEDEDDE	SUGP2	886	Q8IX01
TEEVKEEEEDAQPEP	RHOXF2	36	Q9BQY4
PPSDTDSEEEEEEEE	PHF23	241	Q9BUL5
EKPEEELEEDDDEEL	TOMM22	26	Q9NS69
PATPRDEDLEEEEEE	ZNF316	126	A6NFI3
KAPEPEEEIEEVEES	ZCRB1	141	Q8TBF4
EEEEEEEEEDFKPSD	GTF3C5	491	Q9Y5Q8
DEPEEEEDDEDDLKA	WNK2	171	Q9Y3S1
EDEEEEEEEKDQPAE	VGLL3	66	A8MV65
EEEEEEEEEEEPPPE	STAC3	66	Q96MF2
TIPYEEDEEEEEKEE	SKAP1	216	Q86WV1
EEAELEDSDDEEKPV	TFIP11	91	Q9UBB9
SETQPDEEEEEEEEK	TERF2IP	291	Q9NYB0
DEEEEEEEEKVSQPE	TERF2IP	296	Q9NYB0
EEEEEEIEEPVPAGD	TMED8	246	Q6PL24
LEEEEEEDPEEDRKS	TRERF1	961	Q96PN7
DEEDEEKIDEPIEEE	ZNF326	486	Q5BKZ1
EKIDEPIEEEEDEDE	ZNF326	491	Q5BKZ1
AAEEKEEEPEAEEEE	NEFM	491	P07197