Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24

1.53e-1437468GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24

1.94e-1438468GO:0070001
GeneOntologyMolecularFunctionzinc ion binding

ERVK-8 ERVK-5 ERVK-6 ZCCHC4 KDM2B ZFHX2 RNF216 ERVK-19 MIB2 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24 CRIP1 CSRP1

6.09e-118914616GO:0008270
GeneOntologyMolecularFunctiontransition metal ion binding

ERVK-8 ERVK-5 ERVK-6 ZCCHC4 KDM2B ZFHX2 RNF216 ERVK-19 MIB2 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24 CRIP1 CSRP1

4.10e-0911894616GO:0046914
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10

8.04e-0911464GO:0004523
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10

2.43e-0814464GO:0003964
GeneOntologyMolecularFunctionstructural molecule activity

ERVK-8 ERVK-5 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24 CSRP3 JAG1 CSRP1 CSRP2

6.59e-088914613GO:0005198
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-8 ERVK-6 ERVK-7 ERVK-10

1.43e-0721464GO:0035613
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-8 ERVK-6 ERVK-7 ERVK-10

1.54e-0637464GO:0016891
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10

1.72e-0638464GO:0034061
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-8 ERVK-6 ERVK-7 ERVK-10

3.75e-0646464GO:0016893
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24

5.52e-06430468GO:0004175
GeneOntologyMolecularFunctiongroup III metabotropic glutamate receptor activity

GRM6 GRM8

3.11e-054462GO:0001642
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10

3.26e-0579464GO:0004521
GeneOntologyMolecularFunctionpeptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24

1.10e-04654468GO:0008233
GeneOntologyMolecularFunctionstructural constituent of muscle

CSRP3 CSRP1 CSRP2

1.32e-0443463GO:0008307
GeneOntologyMolecularFunctionactinin binding

CSRP3 CSRP1 CSRP2

1.32e-0443463GO:0042805
GeneOntologyMolecularFunctionG protein-coupled glutamate receptor activity

GRM6 GRM8

1.85e-049462GO:0098988
GeneOntologyMolecularFunctionadenylate cyclase inhibiting G protein-coupled glutamate receptor activity

GRM6 GRM8

1.85e-049462GO:0001640
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

KMT2C SMYD3

2.31e-0410462GO:0140999
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10

2.69e-04136464GO:0004540
GeneOntologyMolecularFunctionendonuclease activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10

2.69e-04136464GO:0004519
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

ERVK-8 ERVK-6 ZCCHC4 ERVK-7 ERVK-10 LARS2

3.70e-04417466GO:0140098
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10

4.11e-04152464GO:0016779
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2C SMYD3

9.61e-0420462GO:0042800
GeneOntologyMolecularFunctionglutamate receptor activity

GRM6 GRM8

1.76e-0327462GO:0008066
GeneOntologyMolecularFunctionN-methyltransferase activity

ZCCHC4 KMT2C SMYD3

1.82e-03105463GO:0008170
GeneOntologyMolecularFunctionnuclease activity

ERVK-8 ERVK-6 ERVK-7 ERVK-10

1.95e-03231464GO:0004518
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

ERVK-8 PROCA1 ERVK-6 ERVK-7 ERVK-10 PLA2G4E LARS2

2.32e-03807467GO:0016788
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-8 ERVK-6 ERVK-7 ERVK-10

3.07e-03262464GO:0140097
GeneOntologyMolecularFunctionphospholipase A2 activity

PROCA1 PLA2G4E

3.28e-0337462GO:0004623
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-8 ERVK-6 ZCCHC4 ERVK-7 ERVK-10 LARS2

3.46e-03645466GO:0140640
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

KMT2C SMYD3

4.62e-0344462GO:0140938
GeneOntologyMolecularFunctioncarboxylic ester hydrolase activity

PROCA1 PLA2G4E LARS2

5.65e-03157463GO:0052689
GeneOntologyMolecularFunctionS-adenosylmethionine-dependent methyltransferase activity

ZCCHC4 KMT2C SMYD3

7.27e-03172463GO:0008757
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

KMT2C SMYD3

1.07e-0268462GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

KMT2C SMYD3

1.10e-0269462GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

KMT2C SMYD3

1.17e-0271462GO:0042054
GeneOntologyMolecularFunctionmethyltransferase activity

ZCCHC4 KMT2C SMYD3

1.30e-02213463GO:0008168
GeneOntologyBiologicalProcessDNA integration

ERVK-8 ERVK-6 ERVK-7 ERVK-10

1.53e-0813464GO:0015074
GeneOntologyBiologicalProcessviral process

ERVK-8 ERVK-5 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24

7.19e-07464469GO:0016032
GeneOntologyBiologicalProcesscell-cell fusion

ERVK-8 ERVK-6 ERVK-19 ERVK-21 ERVK-9

1.27e-0685465GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

ERVK-8 ERVK-6 ERVK-19 ERVK-21 ERVK-9

1.27e-0685465GO:0000768
GeneOntologyBiologicalProcesssyncytium formation

ERVK-8 ERVK-6 ERVK-19 ERVK-21 ERVK-9

1.59e-0689465GO:0006949
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-8 ERVK-6 ERVK-7 ERVK-10

3.92e-0648464GO:0000731
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-8 ERVK-6 ERVK-7 ERVK-10

3.50e-0583464GO:0006278
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

GRM6 GRM8

1.73e-049462GO:0007196
GeneOntologyBiologicalProcesssarcomere organization

CSRP3 CSRP1 CSRP2

3.09e-0459463GO:0045214
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

ERVK-8 ERVK-6 KDM2B LHX2 ERVK-19 ERVK-21 ERVK-9 CSRP3 JAG1 CSRP1 CSRP2

3.27e-0414834611GO:0048646
GeneOntologyBiologicalProcesscamera-type eye development

TDRD7 KDM2B LHX2 KMT2C GRM6 JAG1

3.49e-04426466GO:0043010
GeneOntologyBiologicalProcessG protein-coupled glutamate receptor signaling pathway

GRM6 GRM8

5.72e-0416462GO:0007216
GeneOntologyBiologicalProcesseye development

TDRD7 KDM2B LHX2 KMT2C GRM6 JAG1

6.55e-04480466GO:0001654
GeneOntologyBiologicalProcessDNA-templated DNA replication

ERVK-8 ERVK-6 ERVK-7 ERVK-10

6.59e-04178464GO:0006261
GeneOntologyBiologicalProcessvisual system development

TDRD7 KDM2B LHX2 KMT2C GRM6 JAG1

6.77e-04483466GO:0150063
GeneOntologyBiologicalProcesssensory system development

TDRD7 KDM2B LHX2 KMT2C GRM6 JAG1

7.37e-04491466GO:0048880
DomainLIM

LHX2 ABLIM1 ABLIM2 CSRP3 CRIP1 CSRP1 CSRP2

7.92e-1169387PF00412
Domain-

LHX2 ABLIM1 ABLIM2 CSRP3 CRIP1 CSRP1 CSRP2

8.79e-11703872.10.110.10
DomainLIM_DOMAIN_2

LHX2 ABLIM1 ABLIM2 CSRP3 CRIP1 CSRP1 CSRP2

9.73e-1171387PS50023
DomainZnf_LIM

LHX2 ABLIM1 ABLIM2 CSRP3 CRIP1 CSRP1 CSRP2

9.73e-1171387IPR001781
DomainLIM_DOMAIN_1

LHX2 ABLIM1 ABLIM2 CSRP3 CRIP1 CSRP1 CSRP2

9.73e-1171387PS00478
DomainLIM

LHX2 ABLIM1 ABLIM2 CSRP3 CRIP1 CSRP1 CSRP2

9.73e-1171387SM00132
DomainNCD3G

TAS1R1 GRM6 GRM8

2.19e-0613383PF07562
DomainGPCR_3_9-Cys_dom

TAS1R1 GRM6 GRM8

2.19e-0613383IPR011500
DomainGPCR_3_CS

TAS1R1 GRM6 GRM8

2.78e-0614383IPR017979
DomainGPCR_3

TAS1R1 GRM6 GRM8

1.01e-0521383IPR000337
DomainG_PROTEIN_RECEP_F3_4

TAS1R1 GRM6 GRM8

1.17e-0522383PS50259
Domain7tm_3

TAS1R1 GRM6 GRM8

1.17e-0522383PF00003
DomainGPCR_3_C

TAS1R1 GRM6 GRM8

1.17e-0522383IPR017978
DomainG_PROTEIN_RECEP_F3_2

TAS1R1 GRM6 GRM8

1.17e-0522383PS00980
DomainG_PROTEIN_RECEP_F3_3

TAS1R1 GRM6 GRM8

1.17e-0522383PS00981
DomainG_PROTEIN_RECEP_F3_1

TAS1R1 GRM6 GRM8

1.17e-0522383PS00979
DomainAbLIM_anchor

ABLIM1 ABLIM2

2.41e-054382PF16182
DomainAbLIM_anchor

ABLIM1 ABLIM2

2.41e-054382IPR032402
DomainZF_CCHC

ERVK-5 ERVK-6 ZCCHC4

4.86e-0535383PS50158
DomainANF_receptor

TAS1R1 GRM6 GRM8

5.76e-0537383PF01094
DomainANF_lig-bd_rcpt

TAS1R1 GRM6 GRM8

5.76e-0537383IPR001828
DomainPeripla_BP_I

TAS1R1 GRM6 GRM8

6.75e-0539383IPR028082
DomainVHP

ABLIM1 ABLIM2

1.12e-048382PF02209
DomainVillin_headpiece

ABLIM1 ABLIM2

1.12e-048382IPR003128
DomainHP

ABLIM1 ABLIM2

1.12e-048382PS51089
DomainGPCR_3_mtglu_rcpt

GRM6 GRM8

1.12e-048382IPR000162
Domain-

ABLIM1 ABLIM2

1.12e-0483821.10.950.10
DomainVHP

ABLIM1 ABLIM2

1.12e-048382SM00153
DomainZnF_C2HC

ERVK-5 ERVK-6 ZCCHC4

1.89e-0455383SM00343
DomainZnf_CCHC

ERVK-5 ERVK-6 ZCCHC4

1.89e-0455383IPR001878
DomainEGF_CA

VLDLR EGFL8 JAG1

7.08e-0486383PF07645
Domainzf-CCHC

ERVK-5 ERVK-6

9.93e-0423382PF00098
DomainEGF_Ca-bd_CS

VLDLR EGFL8 JAG1

1.00e-0397383IPR018097
DomainEGF_CA

VLDLR EGFL8 JAG1

1.07e-0399383PS01187
DomainASX_HYDROXYL

VLDLR EGFL8 JAG1

1.10e-03100383PS00010
DomainDHHC

ZCCHC4 KMT2C

1.17e-0325382PS50216
DomainZnf_DHHC_palmitoyltrfase

ZCCHC4 KMT2C

1.17e-0325382IPR001594
DomainEGF-type_Asp/Asn_hydroxyl_site

VLDLR EGFL8 JAG1

1.30e-03106383IPR000152
DomainEGF_CA

VLDLR EGFL8 JAG1

1.94e-03122383SM00179
DomainEGF-like_Ca-bd_dom

VLDLR EGFL8 JAG1

2.03e-03124383IPR001881
DomainEGF

VLDLR EGFL8 JAG1

2.13e-03126383PF00008
DomainZF_RING_2

RNF216 KMT2C MIB2 RNF103

3.06e-03298384PS50089
DomainSET

KMT2C SMYD3

3.14e-0341382PF00856
DomainSET

KMT2C SMYD3

3.94e-0346382SM00317
DomainSET_dom

KMT2C SMYD3

4.64e-0350382IPR001214
DomainSET

KMT2C SMYD3

4.64e-0350382PS50280
DomainFBOX

KDM2B FBXW12

5.01e-0352382SM00256
DomainRetrov_capsid_C

ERVK-5 ERVK-6

6.41e-0359382IPR008916
DomainF-box

KDM2B FBXW12

8.20e-0367382PF00646
DomainFBOX

KDM2B FBXW12

9.42e-0372382PS50181
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

TAS1R1 GRM6 GRM8

5.21e-0537283MM15067
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

TAS1R1 GRM6 GRM8

6.11e-0539283M793
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION

MIB2 JAG1

1.36e-049282M47866
PathwayREACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING

ABLIM1 ABLIM2

3.41e-0414282M889
PathwayWP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE

GRM6 GRM8

3.93e-0415282M39442
PathwayWP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE

GRM6 GRM8

3.93e-0415282MM15845
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

MIB2 JAG1

3.93e-0415282M27202
PathwayWP_H19_RBE2F1_AND_CDKBETACATENIN_IN_COLORECTAL_CANCER

JAG1 CSRP2

4.49e-0416282M39472
PathwayREACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

MIB2 JAG1

8.57e-0422282M27210
PathwayREACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

MIB2 JAG1

1.11e-0325282M27879
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

MIB2 JAG1

1.71e-0331282M592
PathwayREACTOME_SIGNALING_BY_NOTCH2

MIB2 JAG1

1.93e-0333282M604
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-8 ERVK-5 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24

5.27e-159446921542922
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-8 ERVK-6 ERVK-19 ERVK-21 ERVK-9

2.54e-121246514557543
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-5 ERVK-6 ERVK-19 ERVK-10

2.68e-1244647983737
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10 ERVK-24

2.68e-12446410469592
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-19 ERVK-7 ERVK-21

1.34e-11546412629516
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9 ERVK-10 ERVK-24

8.08e-091846418664271
Pubmed

Embryonic expression suggests an important role for CRP2/SmLIM in the developing cardiovascular system.

CSRP3 CSRP1 CSRP2

8.65e-0944639815145
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-5 ERVK-6 ERVK-7

2.16e-08546311401426
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-19 ERVK-9

4.32e-08646315063128
Pubmed

The heart LIM protein gene (Hlp), expressed in the developing and adult heart, defines a new tissue-specific LIM-only protein family.

CSRP3 CSRP1 CSRP2

1.21e-07846312128222
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-19 ERVK-21

2.58e-071046312970426
Pubmed

Loss of the serum response factor cofactor, cysteine-rich protein 1, attenuates neointima formation in the mouse.

CSRP1 CSRP2

1.71e-06246220056913
Pubmed

Abundant cysteine-rich protein-1 is localized in the stromal compartment of the human prostate.

CRIP1 CSRP1

1.71e-0624629507743
Pubmed

Ultraviolet B radiation regulates cysteine-rich protein 1 in human keratinocytes.

CRIP1 CSRP1

1.71e-06246220415737
Pubmed

Targeted disruption of the mouse Csrp2 gene encoding the cysteine- and glycine-rich LIM domain protein CRP2 result in subtle alteration of cardiac ultrastructure.

CSRP3 CSRP2

1.71e-06246218713466
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

1.71e-0624629060628
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

1.71e-0624629460924
Pubmed

PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling.

CSRP3 CSRP2

5.13e-06346218258855
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-19

5.13e-06346210516026
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-9

5.13e-0634629971820
Pubmed

Downregulation of apoptosis-inducing factor in harlequin mutant mice sensitizes the myocardium to oxidative stress-related cell death and pressure overload-induced decompensation.

CSRP3 TXNDC12

1.03e-05446215933268
Pubmed

Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer.

CRIP1 CSRP1

1.03e-05446217486081
Pubmed

Distribution of group-III metabotropic glutamate receptors in the retina.

GRM6 GRM8

1.03e-05446217311335
Pubmed

The cysteine-rich protein family of highly related LIM domain proteins.

CSRP3 CSRP2

1.03e-0544627499425
Pubmed

Genotype patterns that contribute to increased risk for or protection from developing heroin addiction.

GRM6 GRM8

1.71e-05546218195715
Pubmed

Pias1 interaction and sumoylation of metabotropic glutamate receptor 8.

GRM6 GRM8

2.56e-05646216144832
Pubmed

Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin.

ABLIM1 ABLIM2

2.56e-05646217194709
Pubmed

Response to methadone maintenance treatment is associated with the MYOCD and GRM6 genes.

GRM6 GRM8

2.56e-05646220560679
Pubmed

The master transcription factor SOX2, mutated in anophthalmia/microphthalmia, is post-transcriptionally regulated by the conserved RNA-binding protein RBM24 in vertebrate eye development.

LHX2 JAG1

4.77e-05846231814023
Pubmed

Radial glia cells are candidate stem cells of ependymoma.

LHX2 JAG1

6.12e-05946216226707
Pubmed

Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.

GRM6 GRM8

7.65e-05104629069281
Pubmed

The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids.

TAS1R1 GRM8

7.65e-051046217156446
Pubmed

Lhx2 in germ cells suppresses endothelial cell migration in the developing ovary.

LHX2 JAG1

1.12e-041246235337816
Pubmed

Expression patterns of developmental control genes in normal and Engrailed-1 mutant mouse spinal cord reveal early diversity in developing interneurons.

LHX2 JAG1

1.32e-04134629315901
Pubmed

Mash1 and Ngn1 control distinct steps of determination and differentiation in the olfactory sensory neuron lineage.

LHX2 JAG1

1.32e-041346211934853
Pubmed

Six1 is indispensable for production of functional progenitor cells during olfactory epithelial development.

LHX2 JAG1

2.88e-041946221302255
Pubmed

The histone H3K36 demethylase Fbxl11 plays pivotal roles in the development of retinal late-born cell types.

KDM2B LHX2

3.20e-042046237073980
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

ZFHX2 LHX2 KMT2C ABLIM1 RNF103 CSRP2

3.29e-0470946622988430
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KDM2B KMT2C

3.54e-042146227626377
Pubmed

Genetic Labeling of Nuclei-Specific Thalamocortical Neurons Reveals Putative Sensory-Modality Specific Genes.

LHX2 HS6ST3

4.25e-042346227655933
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRM6 GRM8

4.64e-042446235746896
Pubmed

Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis.

LHX2 JAG1

4.64e-042446220808958
Pubmed

Six1 is essential for early neurogenesis in the development of olfactory epithelium.

LHX2 JAG1

4.64e-042446217880938
Pubmed

Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon.

LHX2 JAG1

5.45e-042646212397111
Pubmed

Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation.

LHX2 JAG1

5.88e-042746224148613
Pubmed

Vti1b promotes TRPV1 sensitization during inflammatory pain.

ABLIM2 TXNDC12 CSRP1

6.44e-0412746330335684
Pubmed

Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.

CSRP3 CSRP1 CSRP2

1.08e-0315246311044609
Cytoband7p22.1

ERVK-6 RNF216

9.87e-04474527p22.1
Cytoband1p32.3

DMRTB1 TXNDC12

1.66e-03614521p32.3
GeneFamilyLIM domain containing

ABLIM1 ABLIM2 CSRP3 CRIP1 CSRP1 CSRP2

5.20e-10593061218
GeneFamilyGlutamate metabotropic receptors|Protein phosphatase 1 regulatory subunits

GRM6 GRM8

7.41e-058302281
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2C SMYD3

1.44e-0334302487
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KDM2B ZFHX2 THSD7B CRIP1

9.60e-06166364da10d0be6b616199d49dd922591c2901f9681583
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABLIM1 ABLIM2 EGFL8 JAG1

1.05e-0517036455fe16d98ea284d05fb899888e4569c685644c7b
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IZUMO1 ABLIM1 EGFL8 JAG1

1.13e-05173364b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCellfacs-Skin-nan-24m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 LHX2 LARS2 CSRP1

1.18e-05175364f1166b567bca80dac3abe90c3dc544c831006640
ToppCell15-Airway-Mesenchymal-Pericyte|Airway / Age, Tissue, Lineage and Cell class

CRIP1 JAG1 CSRP1 CSRP2

1.77e-051943645c1218d239c88082496924653ed2a092dc44a906
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CRIP1 JAG1 CSRP1 CSRP2

1.77e-051943645099e6ad7c19e5f8b73449d904aaefd97f1b1959
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CRIP1 JAG1 CSRP1 CSRP2

1.77e-0519436471734ef7b34ab33b349595368176fa0e1175d4d0
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CRIP1 JAG1 CSRP1 CSRP2

1.81e-05195364e10b21e4dba4483efc4c82d6e395524246ca14a8
ToppCellFibroblasts-Pericytes|Fibroblasts / lung cells shred on cell class, cell subclass, sample id

CRIP1 JAG1 CSRP1 CSRP2

1.81e-05195364c2ebc0b33bda9b35b9ef26d69e5d2c6acfdb6ff1
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIP1 JAG1 CSRP1 CSRP2

1.81e-051953645dc874641ad9537e4c1369825c1fb0a59f12a83d
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CRIP1 JAG1 CSRP1 CSRP2

1.84e-051963641d94cecd378a829dd8014fc086d7fca48c953a91
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CRIP1 JAG1 CSRP1 CSRP2

1.84e-05196364aacec48285bcb7ccf1b538187071885e3602cc49
ToppCellKidney-Mesangial|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.

CRIP1 JAG1 CSRP1 CSRP2

1.84e-051963642b2cbe7f96213b7ff50442593f31820d17a2ae94
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIP1 JAG1 CSRP1 CSRP2

1.88e-05197364cc494a656db868bb489238a5becc31bc8518f3cc
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIP1 JAG1 CSRP1 CSRP2

1.88e-0519736415a08b04acb1cb7e84aeb072c650ce07374181f5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRIP1 JAG1 CSRP1 CSRP2

1.92e-0519836477288df94286382170a266474ab85960519e8449
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRIP1 JAG1 CSRP1 CSRP2

1.92e-051983642ee195f20a4f91fa1dcad9eaf96d6086e3b0fb4a
ToppCellcellseq2-Mesenchymal-Myocytic-Myocytic_2-VSMC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CRIP1 JAG1 CSRP1 CSRP2

2.00e-05200364fc802dd73f048881d9ddafd1b79ab3ca654510e2
ToppCellcellseq2-Mesenchymal-Myocytic-Myocytic_2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CRIP1 JAG1 CSRP1 CSRP2

2.00e-05200364cffddb39960cd611428397c1ec4023192e8af5a7
ToppCellcellseq2-Mesenchymal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CRIP1 JAG1 CSRP1 CSRP2

2.00e-052003646b558cce0d6047c7e85f428adff80c5ca3084ea4
ToppCellcellseq2-Mesenchymal-Myocytic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CRIP1 JAG1 CSRP1 CSRP2

2.00e-05200364e60aebd20be8012fa2febf6585ed34ebd64ec9b3
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_B3|TCGA-Thymus / Sample_Type by Project: Shred V9

IZUMO1 PLA2G4E FBXW12

1.53e-04129363c760a1f9b86f086074e6e04e50ab40da3639e5fb
ToppCelldroplet-Fat-SCAT-30m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HS6ST3 FOLR2 CSRP3

2.58e-0415436373de626b210ec5482ba89a65e784c1e77ff2894e
ToppCelldroplet-Fat-SCAT-30m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HS6ST3 FOLR2 CSRP3

2.58e-0415436356fe9953e58f71626d3ddf63d340ed35dfc4ce9f
ToppCellfacs-Heart-Unknown-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G4E LARS2 CSRP3

2.73e-041573632ac4695d9e4ca8d4ba19c555e9a1d86ac8f398ab
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZFHX2 ABLIM2 LARS2

2.73e-041573634766f7d545bf2d775390589460677519cb92f4d5
ToppCellfacs-Heart-Unknown-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G4E LARS2 CSRP3

2.73e-041573638a393eece90fb9a1b7c356736bdb36277261fbd3
ToppCellfacs-Heart-Unknown-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G4E LARS2 CSRP3

2.73e-041573638d30d8e6fae93afcada6bd68799439335cd65b69
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

IZUMO1 JAG1 CSRP2

2.79e-041583638d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCelldroplet-Thymus-nan-21m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROCA1 GRM8 FOLR2

2.94e-04161363441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM1 GRM6 CRIP1

3.00e-0416236315d5d31a75e26bcd41919a00300c68e9f00f0002
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7B HS6ST3 JAG1

3.16e-04165363cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7B HS6ST3 JAG1

3.16e-041653634f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCellfacs-BAT-Fat-24m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMRTB1 LARS2 CSRP3

3.22e-04166363c71ad3fc6a14507609d17756431d3deff9fda418
ToppCellfacs-BAT-Fat-24m-Myeloid|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMRTB1 LARS2 CSRP3

3.22e-04166363001a31aaa4ab4d5606b894faf6fcaad524405064
ToppCellfacs-BAT-Fat-24m-Myeloid-myeloid_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMRTB1 LARS2 CSRP3

3.22e-0416636331ed1290b4a977eabfc29674a5c593985bff6a74
ToppCellmetastatic_Brain-Fibroblasts-Smooth_muscle_cells|metastatic_Brain / Location, Cell class and cell subclass

CRIP1 CSRP1 CSRP2

3.22e-041663630da2c6ea1e62f1aafabafbbfbbcc6f7011739346
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TAS1R1 ZFHX2 KMT2C

3.34e-041683638072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IZUMO1 VLDLR CSRP1

3.45e-041703637fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LHX2 JAG1 CSRP2

3.45e-04170363af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 JAG1 CSRP2

3.70e-04174363778e0317c0c63fa4efd74114feb760975b819d92
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TAS1R1 ZFHX2 HS6ST3

3.70e-04174363271c51d220842402975d97c86c9acfdbdf62a32c
ToppCell(1)_Control_(PBS)-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|(1)_Control_(PBS) / Stress and Cell class

VLDLR LARS2 CRIP1

3.88e-04177363d9e5ac5b8949a77e88e8094079167e4cf2c1bbd1
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM6 CSRP3 CRIP1

3.88e-041773639b4c1ca5c6fca9a7a936dad49a04155903ef9c32
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Tuft|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TAS1R1 ZFHX2 CRIP1

3.95e-04178363f17c3b7bb562ac24c6a03fe3c9ba94c2b434c141
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIP1 JAG1 CSRP2

3.95e-04178363e5e4742e35c3d90f82b830d77bdbdc45828c7deb
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 JAG1 CSRP2

3.95e-041783639fc5688cf705a74398d24e10e0aab4758612e72b
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THSD7B CRIP1 JAG1

3.95e-04178363066dbc4cc2083c549d98122ed44707127f34d582
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMYD3 CRIP1 CSRP2

3.95e-041783631a578d16008a450c42e73a996247ffecdc2c43f0
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

HS6ST3 JAG1 CSRP2

4.01e-04179363111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCellfacs|World / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX2 LARS2 JAG1

4.01e-041793638001db3044e8657980e24422377c4fdb0d7b323e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TAS1R1 ZFHX2 HS6ST3

4.01e-04179363b8ca29aebd25ebac441bebd769bbf98c536d3166
ToppCellE15.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CRIP1 JAG1 CSRP2

4.08e-0418036338035cf2c6fbc443ea10ca7e942572715ed572da
ToppCell18-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

THSD7B CSRP1 CSRP2

4.15e-0418136333938e6521712058312879f84f4ae381c2bfc379
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM6 CSRP3 CRIP1

4.15e-04181363382337427be3c11ecd03e9fa2c2e831a9674c6a7
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 JAG1 CSRP2

4.28e-041833634060d979948e1dd7507977629a7fbdfa4ca65bb6
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 JAG1 CSRP2

4.28e-04183363b4f29dd3994009bb5eb769d36d95886664e7f87d
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HS6ST3 CSRP1 CSRP2

4.28e-0418336361a73de857f4ae02dcba3af348f436f602b28ff2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST3 JAG1 CSRP1

4.28e-04183363667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 JAG1 CSRP2

4.28e-041833630d44a978221cf3f733704bf11863502805fba733
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAG1 CSRP1 CSRP2

4.35e-04184363978135173891c83470370a42b2801e09eb740320
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

ABLIM1 HS6ST3 CSRP3

4.35e-04184363ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAG1 CSRP1 CSRP2

4.35e-04184363f58922cf593f4b739f2713ef88a2ca3014f927e9
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

ABLIM1 HS6ST3 CSRP3

4.42e-041853636baccb26f999145e51b91d94315bf8d4655bef31
ToppCell(5)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

JAG1 CSRP1 CSRP2

4.49e-04186363acbca8cc048d87faf859b3e77bdb38d0a3dad71c
ToppCell(5)_Pericytes-(50)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

JAG1 CSRP1 CSRP2

4.49e-0418636367b59defdd1ed3608229cc5e2a3b480d92312afa
ToppCellThalamus-Endothelial|Thalamus / BrainAtlas - Mouse McCarroll V32

CRIP1 JAG1 CSRP2

4.49e-04186363dcc6e4417c4123d5ca6b96fa8ca4874626aaebdb
ToppCellControl-Endothelial-Endothelial-Artery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EGFL8 GRM8 JAG1

4.49e-041863632d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIP1 JAG1 CSRP2

4.49e-041863636568358812f0ca4e0161a1a1b29682fbced35c79
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-VSMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

JAG1 CSRP1 CSRP2

4.49e-04186363c7885fd6dc7dc8fffc96f0112c51a365cf8a8f80
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIP1 JAG1 CSRP2

4.56e-041873636820bfbe552ea5e62cfe699687b051a17d9fda61
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CRIP1 JAG1 CSRP2

4.56e-04187363406ff9327d3109fe1e251629c4c617b00a573dc2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7B HS6ST3 JAG1

4.56e-04187363530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7B HS6ST3 JAG1

4.56e-04187363ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7B HS6ST3 JAG1

4.56e-04187363958402fcc78f4c7a7d13d659d776f3817137975f
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD7B EGFL8 JAG1

4.56e-04187363e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7B HS6ST3 JAG1

4.56e-0418736348bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

IZUMO1 ABLIM1 GRM8

4.63e-04188363e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellCOPD-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

CRIP1 CSRP1 CSRP2

4.63e-041883639ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCellFrontal_cortex-Endothelial|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CRIP1 JAG1 CSRP2

4.63e-04188363a43392dbd10fc7dbfb31be39b8af8a7ea121c894
ToppCellEntopeduncular-Endothelial|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CRIP1 JAG1 CSRP2

4.63e-0418836394774652fd42bad5012356672ffac8b6d2c22d37
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIP1 JAG1 CSRP1

4.63e-04188363c2321a3a1d9603f8b4b4fc09707eb32ec1e04f3f
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

CRIP1 JAG1 CSRP2

4.70e-04189363f4865b7db16de15120504147a8016ac522ad242a
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 JAG1 CSRP2

4.70e-041893631e1afa66b32ae752c0a42b02b80f10205464569c
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VLDLR JAG1 CSRP2

4.70e-04189363d0c7549be4f77520c23dddf4f94d0fcad0081e37
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABLIM1 EGFL8 JAG1

4.70e-04189363c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 JAG1 CSRP2

4.78e-041903637df63e5e0dd395676f4fc18cad0d8b2428390943
ToppCellP07|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ABLIM1 CRIP1 CSRP1

4.78e-0419036338a613a9bca0ba040c3ada00286d1ce6f83ab23a
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABLIM1 EGFL8 JAG1

4.78e-04190363aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 JAG1 CSRP2

4.78e-04190363140aca04c044cd7a93f81ff1631b00b5216d2cb1
ToppCellCOVID-19-kidney-vSMC/Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

JAG1 CSRP1 CSRP2

4.85e-04191363fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIP1 JAG1 CSRP2

4.85e-041913639431ffd6b758f756609d9057de2023596e22b5d4
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EGFL8 GRM8 JAG1

4.85e-041913634b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIP1 JAG1 CSRP2

4.85e-04191363239c1e68eb1cbe3e137a99fbd6eeb8d64c919ffd
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR PLA2G4E CSRP3

4.85e-04191363715f5b449b8e075959c05a5b38389df319663164
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR PLA2G4E CSRP3

4.85e-04191363c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCellIPF-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

CRIP1 CSRP1 CSRP2

4.92e-041923639b06c7336624ef21f8e5393725b56038a8028e57
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

JAG1 CSRP1 CSRP2

4.92e-04192363b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIP1 JAG1 CSRP2

4.92e-0419236371863f18a82394ed9f8e5ec8a4017215382a8284
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRIP1 JAG1 CSRP2

4.92e-04192363dee97f650ae6f4d07a142ade402aae1905791a22
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

CRIP1 JAG1 CSRP1 CSRP2

3.44e-0650234GAVISH_3CA_METAPROGRAM_FIBROBLASTS_PERICYTE_LIKE
Drug1-amino-2-phosphonomethylcyclopropanecarboxylic acid

GRM6 GRM8

8.57e-063392ctd:C523415
DrugAC1NQH9B

ERVK-6 GRM6 GRM8

1.18e-0526393CID005221504
DrugLY393675

GRM6 GRM8

2.85e-055392CID005311262
DrugDMeOB

GRM6 GRM8

2.85e-055392CID002061047
Drugtyrphostin B52

GRM6 GRM8

2.85e-055392CID005328773
Drugmagnesium perchlorate hexahydrate

ERVK-6 LHX2

2.85e-055392CID006431880
DrugMTEP

GRM6 GRM8

4.27e-056392CID009794218
DrugSIB-1757

GRM6 GRM8

4.27e-056392CID006304902
DrugAC1MBZ3L

GRM6 GRM8

4.27e-056392CID002733524
DrugCDPPB

GRM6 GRM8

5.97e-057392CID011245456
Drugazetidine-2,4-dicarboxylic acid

GRM6 GRM8

5.97e-057392CID000005370
DrugMCCG-I

GRM6 GRM8

5.97e-057392CID005311457
Drugcis-MCG-I

GRM6 GRM8

7.95e-058392CID003035584
Drug1,3-cyclopentanedicarboxylic acid

GRM6 GRM8

1.02e-049392CID000107216
DrugmM PEP

GRM6 GRM8

1.02e-049392CID005311462
DrugAC1N21PP

GRM6 GRM8

1.02e-049392CID004014619
DrugNS-105

GRM6 GRM8

1.28e-0410392CID000198695
DrugMesG

TAS1R1 GRM6 GRM8

1.34e-0458393CID003035490
Drugcyclobutylene AP5

GRM6 GRM8

1.56e-0411392CID000126582
DrugN-anisoyl-GABA

GRM6 GRM8

1.56e-0411392CID000155723
DrugAP-7

GRM6 GRM8 JAG1

1.72e-0463393CID000003122
DrugAMN082

GRM6 GRM8

1.87e-0412392CID001894360
DrugAC1NSKBB

GRM6 GRM8

2.20e-0413392CID005311256
DrugMspg

GRM6 GRM8

2.20e-0413392CID003964410
DrugMSOPPE

GRM6 GRM8

2.20e-0413392CID005311463
Diseasecorpus collosum mid-posterior volume measurement

VLDLR JAG1

4.51e-0425372EFO_0010300
Diseasepyridoxate measurement

THSD7B SMYD3

6.95e-0431372EFO_0010527
DiseaseSchizophrenia

ERVK-8 KDM2B VLDLR LARS2 GRM8 JAG1

7.43e-04883376C0036341
Diseasemultiple sclerosis (is_marker_for)

GRM8 JAG1

1.73e-0349372DOID:2377 (is_marker_for)
DiseaseNon-alcoholic Fatty Liver Disease

VLDLR FOLR2

3.50e-0370372C0400966
DiseaseNonalcoholic Steatohepatitis

VLDLR FOLR2

3.50e-0370372C3241937
DiseaseAdenoid Cystic Carcinoma

KMT2C JAG1

7.01e-03100372C0010606

Protein segments in the cluster

PeptideGeneStartEntry
CCQGWKKRHPGALTC

EGFL8

96

Q99944
WHLGCFKCKSCGKVL

ABLIM1

246

O14639
KMLSEHLCGCWKQCP

GVINP1

2276

Q7Z2Y8
KHWHLGCFKCKSCGK

ABLIM2

171

Q6H8Q1
GKDWHRPCLKCEKCG

CRIP1

21

P50238
KIPCHCGAVNCRKWM

KMT2C

4896

Q8NEZ4
GKSWHKACFRCAKCG

CSRP1

136

P21291
HKLCASACWTPKVKN

FBXW12

281

Q6X9E4
KQWHMRCLKCCECKL

LHX2

71

P50458
KCWNRSGHCRKQCKD

DEFB118

26

Q96PH6
KKTVKGVPCCWHCER

GRM8

526

O00222
QKKCTCHRPGKKETW

HS6ST3

181

Q8IZP7
WSCGLCCRSRKKGPI

PLA2G4E

281

Q3MJ16
LCPRCKKGKHWASQC

ERVK-10

581

P87889
LCPRCKKGKHWASQC

ERVK-19

581

Q9YNA8
LCPRCKKGKHWASQC

ERVK-21

581

P62683
LCPRCKKGKHWASQC

ERVK-24

581

P63145
LCPKCGKGKHWANQC

ERVK-5

581

Q9HDB9
LCPRCKKGKHWASQC

ERVK-6

581

Q7LDI9
LCPRCKKGKHWASQC

ERVK-7

581

P63130
LCPRCKKGKHWASQC

ERVK-8

581

P62685
LCPRCKKGKHWASQC

ERVK-9

581

P63126
LCPRCKKGKHWASQC

HERVK_113

581

P62684
ERKKMVKGVPCCWHC

GRM6

526

O15303
CWECPKCNHAGKTGK

KDM2B

716

Q8NHM5
GKPWHKNCFRCAKCG

CSRP2

136

Q16527
HAGKCRWKQCLCEKC

DMRTB1

26

Q96MA1
KLHDQCSPWKKNACC

FOLR2

46

P14207
LIWCKNCKKEVHACR

IZUMO1

146

Q8IYV9
GGKPWHKTCFRCAIC

CSRP3

136

P50461
RHCCPVCRWPSYKKK

RNF103

656

O00237
CKEPDKCCWRHKQCT

PROCA1

61

Q8NCQ7
CDCKNGWKGKTCHSR

JAG1

691

P78504
CDCCKKHGLRGMRWK

MIB2

91

Q96AX9
WVNCSCPRCKGAAKR

LARS2

501

Q15031
HRWCSNKKKCCCNGP

KIR3DS1

361

Q14943
PHCRKETCRKCQGLW

RNF216

626

Q9NWF9
CGKICLFHCKGKWLR

TDRD7

706

Q8NHU6
PCTCIGKECQCKRWH

OSER1

196

Q9NX31
CSAKCQKKAWPDHKR

SMYD3

71

Q9H7B4
LCPRCKKGKHWASQC

ERVK-9

581

P63128
DTWLPKKCSLCKCWH

TDGF1

121

P13385
KKCSLCKCWHGQLRC

TDGF1

126

P13385
KKAPRPCHKGSWCSS

TAS1R1

346

Q7RTX1
SRNSCKTLKCPKCNW

ZFHX2

446

Q9C0A1
RKWNHCFLCKKCVKP

ZCCHC4

406

Q9H5U6
CFLCKKCVKPSWIHC

ZCCHC4

411

Q9H5U6
LPWSNCSKGCGKKLQ

THSD7B

186

Q9C0I4
LRSKMGKWCCHCFPC

POTEH

131

Q6S545
DTWLPKKCSLCKCWH

TDGF1P3

121

P51864
KKCSLCKCWHGQLRC

TDGF1P3

126

P51864
IHKSWCGACKALKPK

TXNDC12

61

O95881
CIHKKWRCDGDPDCK

VLDLR

251

P98155