Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH7 DNAH12 DNAH17 DNAH8 DNAH11	1.89e-08	18	96	5	GO:0008569
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH7 DNAH12 DNAH17 DNAH8 DNAH11	2.08e-07	28	96	5	GO:0051959
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH7 DNAH12 DNAH17 DNAH8 DNAH11	8.92e-07	37	96	5	GO:0045505
GeneOntologyMolecularFunction	microtubule motor activity	DNAH7 DNAH12 DNAH17 DNAH8 DNAH11	2.19e-05	70	96	5	GO:0003777
GeneOntologyMolecularFunction	phosphatidate phosphatase activity	LPIN3 LPIN1 LPIN2	3.77e-05	14	96	3	GO:0008195
GeneOntologyMolecularFunction	lipid phosphatase activity	LPIN3 LPIN1 LPIN2	9.87e-05	19	96	3	GO:0042577
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH7 DNAH12 DNAH17 DNAH8 DNAH11	2.64e-04	118	96	5	GO:0003774
GeneOntologyBiologicalProcess	positive regulation of cyclase activity	ADCY4 ADCY1 NOS1 CAP2 CAP1	2.59e-06	48	94	5	GO:0031281
GeneOntologyBiologicalProcess	positive regulation of lyase activity	ADCY4 ADCY1 NOS1 CAP2 CAP1	2.87e-06	49	94	5	GO:0051349
GeneOntologyBiologicalProcess	regulation of cyclase activity	ADCY4 ADCY1 NOS1 CAP2 CAP1	1.58e-05	69	94	5	GO:0031279
GeneOntologyBiologicalProcess	activation of adenylate cyclase activity	ADCY4 ADCY1 CAP2 CAP1	1.69e-05	34	94	4	GO:0007190
GeneOntologyBiologicalProcess	regulation of lyase activity	ADCY4 ADCY1 NOS1 CAP2 CAP1	2.08e-05	73	94	5	GO:0051339
GeneOntologyBiologicalProcess	positive regulation of adenylate cyclase activity	ADCY4 ADCY1 CAP2 CAP1	3.26e-05	40	94	4	GO:0045762
GeneOntologyBiologicalProcess	cilium movement involved in cell motility	DNAH7 CFAP54 DNAH12 DNAH17 CFAP44 DNAH8 DNAH11	4.96e-05	210	94	7	GO:0060294
GeneOntologyBiologicalProcess	cilium-dependent cell motility	DNAH7 CFAP54 DNAH12 DNAH17 CFAP44 DNAH8 DNAH11	5.76e-05	215	94	7	GO:0060285
GeneOntologyBiologicalProcess	cilium or flagellum-dependent cell motility	DNAH7 CFAP54 DNAH12 DNAH17 CFAP44 DNAH8 DNAH11	5.76e-05	215	94	7	GO:0001539
GeneOntologyBiologicalProcess	regulation of adenylate cyclase activity	ADCY4 ADCY1 CAP2 CAP1	1.52e-04	59	94	4	GO:0045761
GeneOntologyBiologicalProcess	cilium movement	DNAH7 CFAP54 DNAH12 DNAH17 CFAP44 DNAH8 DNAH11	1.92e-04	261	94	7	GO:0003341
GeneOntologyCellularComponent	dynein complex	DYNC2I1 DNAH7 DNAH12 DNAH17 DNAH8 DNAH11	1.73e-07	54	96	6	GO:0030286
GeneOntologyCellularComponent	axonemal dynein complex	DNAH7 DNAH12 DNAH17 DNAH8	4.91e-06	25	96	4	GO:0005858
GeneOntologyCellularComponent	microtubule associated complex	DYNC2I1 DNAH7 DNAH12 DNAH17 DNAH8 DNAH11	9.95e-05	161	96	6	GO:0005875
GeneOntologyCellularComponent	motile cilium	ACE DNAH7 DNAH12 DNAH17 TAS2R46 CFAP44 DNAH8 DNAH11	2.31e-04	355	96	8	GO:0031514
GeneOntologyCellularComponent	cilium	DYNC2I1 ACE DNAH7 FBXW8 CFAP54 DNAH12 SLC24A4 DNAH17 TAS2R46 CFAP44 USP48 DNAH8 DNAH11	2.32e-04	898	96	13	GO:0005929
GeneOntologyCellularComponent	axoneme	DNAH7 CFAP54 DNAH12 DNAH17 DNAH8 DNAH11	3.88e-04	207	96	6	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	DNAH7 CFAP54 DNAH12 DNAH17 DNAH8 DNAH11	3.98e-04	208	96	6	GO:0097014
GeneOntologyCellularComponent	9+2 motile cilium	ACE DNAH7 DNAH12 DNAH17 DNAH8 DNAH11	8.07e-04	238	96	6	GO:0097729
GeneOntologyCellularComponent	inner dynein arm	DNAH7 DNAH12	9.17e-04	10	96	2	GO:0036156
GeneOntologyCellularComponent	outer dynein arm	DNAH17 DNAH8	1.34e-03	12	96	2	GO:0036157
MousePheno	abnormal uvea morphology	NDST1 UBE3B LYST SH3PXD2B TRPM3 TRPM1 NOS1 CAP2	2.61e-05	241	70	8	MP:0005197
MousePheno	abnormal iris morphology	NDST1 UBE3B LYST SH3PXD2B TRPM3 TRPM1 CAP2	4.77e-05	192	70	7	MP:0001322
MousePheno	abnormal anterior uvea morphology	NDST1 UBE3B LYST SH3PXD2B TRPM3 TRPM1 CAP2	5.99e-05	199	70	7	MP:0005194
Domain	Lipin_N	LPIN3 LPIN1 LPIN2	1.12e-07	3	91	3	IPR007651
Domain	Lipin_mid	LPIN3 LPIN1 LPIN2	1.12e-07	3	91	3	PF16876
Domain	Lipin_mid	LPIN3 LPIN1 LPIN2	1.12e-07	3	91	3	IPR031703
Domain	Lipin_N	LPIN3 LPIN1 LPIN2	1.12e-07	3	91	3	PF04571
Domain	Dynein_heavy_chain_D4_dom	DNAH7 DNAH12 DNAH8 DNAH11	5.09e-07	14	91	4	IPR024317
Domain	Dynein_heavy_dom-2	DNAH7 DNAH12 DNAH8 DNAH11	5.09e-07	14	91	4	IPR013602
Domain	DHC_N2	DNAH7 DNAH12 DNAH8 DNAH11	5.09e-07	14	91	4	PF08393
Domain	AAA_8	DNAH7 DNAH12 DNAH8 DNAH11	5.09e-07	14	91	4	PF12780
Domain	DHC_fam	DNAH7 DNAH12 DNAH8 DNAH11	6.91e-07	15	91	4	IPR026983
Domain	Dynein_heavy_dom	DNAH7 DNAH12 DNAH8 DNAH11	6.91e-07	15	91	4	IPR004273
Domain	Dynein_heavy	DNAH7 DNAH12 DNAH8 DNAH11	6.91e-07	15	91	4	PF03028
Domain	LNS2	LPIN3 LPIN1 LPIN2	2.21e-06	6	91	3	PF08235
Domain	LNS2	LPIN3 LPIN1 LPIN2	2.21e-06	6	91	3	IPR013209
Domain	LNS2	LPIN3 LPIN1 LPIN2	2.21e-06	6	91	3	SM00775
Domain	LNS2/PITP	LPIN3 LPIN1 LPIN2	2.21e-06	6	91	3	IPR031315
Domain	Adenylate_cyclase-assoc_CAP_N	CAP2 CAP1	2.35e-05	2	91	2	IPR013992
Domain	CAP_N	CAP2 CAP1	2.35e-05	2	91	2	PF01213
Domain	Adenylate_cyclase-assoc_CAP	CAP2 CAP1	2.35e-05	2	91	2	IPR001837
Domain	CAP_CS_N	CAP2 CAP1	2.35e-05	2	91	2	IPR018106
Domain	CAP_2	CAP2 CAP1	2.35e-05	2	91	2	PS01089
Domain	CAP_1	CAP2 CAP1	2.35e-05	2	91	2	PS01088
Domain	CAP_CS_C	CAP2 CAP1	2.35e-05	2	91	2	IPR028417
Domain	CAP_C	CAP2 CAP1	2.35e-05	2	91	2	PF08603
Domain	Dynein_HC_stalk	DNAH7 DNAH8 DNAH11	3.92e-05	14	91	3	IPR024743
Domain	MT	DNAH7 DNAH8 DNAH11	3.92e-05	14	91	3	PF12777
Domain	ATPase_dyneun-rel_AAA	DNAH12 DNAH8 DNAH11	3.92e-05	14	91	3	IPR011704
Domain	AAA_5	DNAH12 DNAH8 DNAH11	3.92e-05	14	91	3	PF07728
Domain	Adenylate_cyclase-assoc_CAP_C	CAP2 CAP1	1.40e-04	4	91	2	IPR013912
Domain	GPR107-like	GPR107 TMEM87B	1.40e-04	4	91	2	IPR009637
Domain	TRPM_tetra	TRPM3 TRPM1	1.40e-04	4	91	2	IPR032415
Domain	TRPM_tetra	TRPM3 TRPM1	1.40e-04	4	91	2	PF16519
Domain	Lung_7-TM_R	GPR107 TMEM87B	1.40e-04	4	91	2	PF06814
Domain	C-CAP_CF_C-like	CAP2 CAP1	2.33e-04	5	91	2	IPR017901
Domain	CARP	CAP2 CAP1	2.33e-04	5	91	2	SM00673
Domain	CAP/MinC_C	CAP2 CAP1	2.33e-04	5	91	2	IPR016098
Domain	CARP_motif	CAP2 CAP1	2.33e-04	5	91	2	IPR006599
Domain	-	CAP2 CAP1	2.33e-04	5	91	2	2.160.20.70
Domain	C_CAP_COFACTOR_C	CAP2 CAP1	2.33e-04	5	91	2	PS51329
Domain	DHC_N1	DNAH8 DNAH11	6.45e-04	8	91	2	PF08385
Domain	AC_N	ADCY4 ADCY1	6.45e-04	8	91	2	IPR032628
Domain	Adcy	ADCY4 ADCY1	6.45e-04	8	91	2	IPR030672
Domain	AC_N	ADCY4 ADCY1	6.45e-04	8	91	2	PF16214
Domain	Dynein_heavy_dom-1	DNAH8 DNAH11	6.45e-04	8	91	2	IPR013594
Domain	AAA+_ATPase	RNF213 DNAH7 DNAH12 DNAH8 DNAH11	6.94e-04	144	91	5	IPR003593
Domain	AAA	RNF213 DNAH7 DNAH12 DNAH8 DNAH11	6.94e-04	144	91	5	SM00382
Domain	PNT	EHF ELF3	1.25e-03	11	91	2	PS51433
Domain	Pointed_dom	EHF ELF3	1.25e-03	11	91	2	IPR003118
Domain	SAM_PNT	EHF ELF3	1.25e-03	11	91	2	PF02198
Domain	SAM_PNT	EHF ELF3	1.25e-03	11	91	2	SM00251
Domain	PX	SNX19 SGK3 SH3PXD2B	1.28e-03	44	91	3	SM00312
Domain	PX	SNX19 SGK3 SH3PXD2B	1.75e-03	49	91	3	PF00787
Domain	PX	SNX19 SGK3 SH3PXD2B	1.86e-03	50	91	3	PS50195
Domain	Phox	SNX19 SGK3 SH3PXD2B	2.08e-03	52	91	3	IPR001683
Domain	Quinoprotein_ADH-like_supfam	AASDH FBXW8 PWP2	2.20e-03	53	91	3	IPR011047
Domain	A/G_cyclase_CS	ADCY4 ADCY1	3.04e-03	17	91	2	IPR018297
Domain	Nucleotide_cyclase	ADCY4 ADCY1	3.41e-03	18	91	2	IPR029787
Domain	-	ADCY4 ADCY1	3.41e-03	18	91	2	3.30.70.1230
Domain	-	LPIN3 LPIN1 LPIN2	3.76e-03	64	91	3	3.40.50.1000
Domain	GUANYLATE_CYCLASE_1	ADCY4 ADCY1	3.80e-03	19	91	2	PS00452
Domain	Guanylate_cyc	ADCY4 ADCY1	3.80e-03	19	91	2	PF00211
Domain	GUANYLATE_CYCLASE_2	ADCY4 ADCY1	3.80e-03	19	91	2	PS50125
Domain	A/G_cyclase	ADCY4 ADCY1	3.80e-03	19	91	2	IPR001054
Domain	CYCc	ADCY4 ADCY1	3.80e-03	19	91	2	SM00044
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH7 DNAH12 DNAH17 DNAH8 DNAH11	2.74e-07	27	75	5	M47755
Pathway	KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT	DNAH7 DNAH12 DNAH17 DNAH8 DNAH11	3.06e-06	43	75	5	M47669
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH7 DNAH12 DNAH17 DNAH8 DNAH11	3.85e-06	45	75	5	M47670
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	BEST1 TRPC4AP ANO5 SGK3 TRPM3 TRPM1	1.40e-05	99	75	6	MM14910
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	BEST1 TRPC4AP ANO5 SGK3 TRPM3 TRPM1	2.07e-05	106	75	6	M27200
Pathway	REACTOME_DEPOLYMERIZATION_OF_THE_NUCLEAR_LAMINA	LPIN3 LPIN1 LPIN2	3.07e-05	12	75	3	MM15105
Pathway	REACTOME_SYNTHESIS_OF_PE	LPIN3 LPIN1 LPIN2	3.07e-05	12	75	3	MM14586
Pathway	REACTOME_TRIGLYCERIDE_BIOSYNTHESIS	LPIN3 LPIN1 LPIN2	3.07e-05	12	75	3	MM15447
Pathway	REACTOME_SYNTHESIS_OF_PE	LPIN3 LPIN1 LPIN2	3.98e-05	13	75	3	M656
Pathway	REACTOME_TRIGLYCERIDE_BIOSYNTHESIS	LPIN3 LPIN1 LPIN2	5.05e-05	14	75	3	M619
Pathway	REACTOME_DEPOLYMERIZATION_OF_THE_NUCLEAR_LAMINA	LPIN3 LPIN1 LPIN2	6.29e-05	15	75	3	M27360
Pathway	WP_CONGENITAL_GENERALIZED_LIPODYSTROPHY	LPIN3 LPIN1 LPIN2	1.11e-04	18	75	3	M42546
Pathway	WP_ETHER_LIPID_BIOSYNTHESIS	LPIN3 LPIN1 LPIN2	1.55e-04	20	75	3	M46451
Pathway	REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN	RGPD2 LPIN3 LPIN1 LPIN2	2.05e-04	55	75	4	MM14917
Pathway	REACTOME_TRIGLYCERIDE_METABOLISM	LPIN3 LPIN1 LPIN2	2.37e-04	23	75	3	MM15575
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	BEST1 TRPC4AP ANO5 SGK3 TRPM3 TRPM1	3.43e-04	176	75	6	MM15718
Pathway	REACTOME_SYNTHESIS_OF_PC	LPIN3 LPIN1 LPIN2	3.44e-04	26	75	3	MM14584
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	BEST1 TRPC4AP ANO5 SGK3 TRPM3 TRPM1	4.23e-04	183	75	6	M997
Pathway	REACTOME_SYNTHESIS_OF_PC	LPIN3 LPIN1 LPIN2	4.31e-04	28	75	3	M684
Pathway	REACTOME_TRP_CHANNELS	TRPC4AP TRPM3 TRPM1	4.31e-04	28	75	3	MM14943
Pathway	REACTOME_TRP_CHANNELS	TRPC4AP TRPM3 TRPM1	4.31e-04	28	75	3	M27241
Pathway	WP_GLYCEROPHOSPHOLIPID_BIOSYNTHETIC_PATHWAY	LPIN1 PIK3CG LPIN2	5.30e-04	30	75	3	M39592
Pathway	WP_ADIPOGENESIS	STAT3 PLIN2 LPIN3 LPIN1 LPIN2	6.58e-04	131	75	5	M39505
Pathway	REACTOME_ROLE_OF_ABL_IN_ROBO_SLIT_SIGNALING	CAP2 CAP1	7.66e-04	8	75	2	M27351
Pathway	REACTOME_INTERLEUKIN_23_SIGNALING	STAT3 IL23R	7.66e-04	8	75	2	MM15619
Pathway	WP_ADIPOGENESIS_GENES	STAT3 PLIN2 LPIN3 LPIN1 LPIN2	8.06e-04	137	75	5	MM15970
Pathway	REACTOME_INTERLEUKIN_23_SIGNALING	STAT3 IL23R	9.81e-04	9	75	2	M27896
Pathway	REACTOME_TRIGLYCERIDE_METABOLISM	LPIN3 LPIN1 LPIN2	1.07e-03	38	75	3	M27856
Pathway	REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY	ADCY4 ADCY1	1.22e-03	10	75	2	M19522
Pathway	REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY	ADCY4 ADCY1	1.22e-03	10	75	2	MM14668
Pathway	KEGG_MEDICUS_REFERENCE_IL12_23_TO_JAK_STAT_SIGNALING_PATHWAY	STAT3 IL23R	1.22e-03	10	75	2	M47907
Pathway	WP_OPIOID_RECEPTOR_PATHWAYS	ADCY1 PIK3CG CAP1	1.33e-03	41	75	3	M48338
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH7 DNAH12 DNAH17 DNAH8 DNAH11	2.98e-10	14	97	5	9373155
Pubmed	Adipose tissue deficiency, glucose intolerance, and increased atherosclerosis result from mutation in the mouse fatty liver dystrophy (fld) gene.	LPIN3 LPIN1 LPIN2	2.10e-08	3	97	3	10884287
Pubmed	Temporal and spatial regulation of the phosphatidate phosphatases lipin 1 and 2.	LPIN3 LPIN1 LPIN2	2.10e-08	3	97	3	18694939
Pubmed	Identification of lipidomic profiles associated with drug-resistant prostate cancer cells.	LPIN3 LPIN1 LPIN2	2.10e-08	3	97	3	33596934
Pubmed	Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis.	LPIN3 LPIN1 LPIN2	2.10e-08	3	97	3	30507612
Pubmed	Lipin proteins form homo- and hetero-oligomers.	LPIN3 LPIN1 LPIN2	2.10e-08	3	97	3	20735359
Pubmed	Study of LPIN1, LPIN2 and LPIN3 in rhabdomyolysis and exercise-induced myalgia.	LPIN3 LPIN1 LPIN2	2.10e-08	3	97	3	22481384
Pubmed	Lipin-1 and lipin-3 together determine adiposity in vivo.	LPIN3 LPIN1 LPIN2	2.10e-08	3	97	3	24634820
Pubmed	Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns.	LPIN3 LPIN1 LPIN2	2.10e-08	3	97	3	17158099
Pubmed	Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin.	LPIN3 LPIN1 LPIN2	8.40e-08	4	97	3	11138012
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH12 DNAH8 DNAH11	7.30e-07	7	97	3	9256245
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH17 DNAH8 DNAH11	7.30e-07	7	97	3	31178125
Pubmed	A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2.	LPIN1 LPIN2	7.70e-06	2	97	2	19717560
Pubmed	Comparison of human CAP and CAP2, homologs of the yeast adenylyl cyclase-associated proteins.	CAP2 CAP1	7.70e-06	2	97	2	7962207
Pubmed	Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation.	EHF ELF3	7.70e-06	2	97	2	18475289
Pubmed	ESE-1 is a potent repressor of type II collagen gene (COL2A1) transcription in human chondrocytes.	EHF ELF3	7.70e-06	2	97	2	18044710
Pubmed	Distinct roles of the phosphatidate phosphatases lipin 1 and 2 during adipogenesis and lipid droplet biogenesis in 3T3-L1 cells.	LPIN1 LPIN2	7.70e-06	2	97	2	24133206
Pubmed	Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury.	NOS1 SOD2	7.70e-06	2	97	2	17394464
Pubmed	Regulation of Mn-superoxide dismutase activity and neuroprotection by STAT3 in mice after cerebral ischemia.	STAT3 SOD2	7.70e-06	2	97	2	19474327
Pubmed	Pilot study of variants of the IL-23R and STAT3 genes reveals no association with Hashimoto's thyroiditis in the Croatian population.	STAT3 IL23R	7.70e-06	2	97	2	24460100
Pubmed	Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum.	LPIN1 LPIN2	7.70e-06	2	97	2	22908270
Pubmed	Paracrine factors from human placental multipotent mesenchymal stromal cells protect endothelium from oxidative injury via STAT3 and manganese superoxide dismutase activation.	STAT3 SOD2	7.70e-06	2	97	2	20107204
Pubmed	Cyclase-associated protein interacts with actin filament barbed ends to promote depolymerization and formin displacement.	CAP2 CAP1	7.70e-06	2	97	2	37863260
Pubmed	Differential Roles of Lipin1 and Lipin2 in the Hepatitis C Virus Replication Cycle.	LPIN1 LPIN2	7.70e-06	2	97	2	31752156
Pubmed	Lipin deactivation after acetaminophen overdose causes phosphatidic acid accumulation in liver and plasma in mice and humans and enhances liver regeneration.	LPIN1 LPIN2	7.70e-06	2	97	2	29534981
Pubmed	Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions.	TRPM3 TRPM1	7.70e-06	2	97	2	21278253
Pubmed	Haploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and nucleocytoplasmic localization of Lipin1.	LPIN3 LPIN1	7.70e-06	2	97	2	37776435
Pubmed	The fatty liver dystrophy (fld) mutation. A new mutant mouse with a developmental abnormality in triglyceride metabolism and associated tissue-specific defects in lipoprotein lipase and hepatic lipase activities.	LPIN1 LPIN2	7.70e-06	2	97	2	2722772
Pubmed	The phosphatidic acid-binding, polybasic domain is responsible for the differences in the phosphoregulation of lipins 1 and 3.	LPIN3 LPIN1	7.70e-06	2	97	2	28982975
Pubmed	Activation of EHF via STAT3 phosphorylation by LMP2A in Epstein-Barr virus-positive gastric cancer.	STAT3 EHF	7.70e-06	2	97	2	34014591
Pubmed	Stat3 contributes to cancer progression by regulating Jab1/Csn5 expression.	STAT3 COPS5	7.70e-06	2	97	2	27524414
Pubmed	JAB1 regulates unphosphorylated STAT3 DNA-binding activity through protein-protein interaction in human colon cancer cells.	STAT3 COPS5	7.70e-06	2	97	2	23911788
Pubmed	CAP2, cyclase-associated protein 2, is a dual compartment protein.	CAP2 CAP1	7.70e-06	2	97	2	17805484
Pubmed	IL-23R in laryngeal cancer: a cancer immunoediting process that facilitates tumor cell proliferation and results in cisplatin resistance.	STAT3 IL23R	7.70e-06	2	97	2	32526010
Pubmed	Arp2/3 complex ATP hydrolysis promotes lamellipodial actin network disassembly but is dispensable for assembly.	CAP2 CAP1	7.70e-06	2	97	2	23439681
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK3 TCAF1 RNF213 SAMD9L TRPM3 DNAH17 FAM169A MED12 PCYOX1	1.02e-05	493	97	9	15368895
Pubmed	Cortical adenylyl cyclase 1 is required for thalamocortical synapse maturation and aspects of layer IV barrel development.	ADCY1 CAP1	2.31e-05	3	97	2	18524897
Pubmed	STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function.	STAT3 IL23R	2.31e-05	3	97	2	25941256
Pubmed	N-terminal acetylation and the N-end rule pathway control degradation of the lipid droplet protein PLIN2.	MARCHF6 PLIN2	2.31e-05	3	97	2	30425097
Pubmed	Associations Between Genetic Polymorphisms in the VEGFA, ACE, and SOD2 Genes and Susceptibility to Diabetic Nephropathy in the Han Chinese.	ACE SOD2	2.31e-05	3	97	2	31524543
Pubmed	Tryptophan degradation enzymes and Angiotensin (1-7) expression in human placenta.	TDO2 ACE	2.31e-05	3	97	2	35970080
Pubmed	Influence of genetic polymorphisms of IL23R, STAT3, IL12B, and STAT4 on the risk of aplastic anemia and the effect of immunosuppressive therapy.	STAT3 IL23R	2.31e-05	3	97	2	29330562
Pubmed	The oxoglutarate receptor 1 (OXGR1) modulates pressure overload-induced cardiac hypertrophy in mice.	STAT3 COPS5	2.31e-05	3	97	2	27693579
Pubmed	A novel form of capsaicin-modified amygdala LTD mediated by TRPM1.	TRPM1 NOS1	2.31e-05	3	97	2	27633915
Pubmed	Cyclase-associated protein 1 (CAP1) promotes cofilin-induced actin dynamics in mammalian nonmuscle cells.	CAP2 CAP1	2.31e-05	3	97	2	15004221
Pubmed	Stat3 and CCAAT/enhancer binding protein beta (C/EBP-beta) regulate Jab1/CSN5 expression in mammary carcinoma cells.	STAT3 COPS5	2.31e-05	3	97	2	21689417
Pubmed	Act1 is a negative regulator in T and B cells via direct inhibition of STAT3.	STAT3 IL23R	2.31e-05	3	97	2	30013031
Pubmed	IL-23R-activated STAT3/STAT4 is essential for Th1/Th17-mediated CNS autoimmunity.	STAT3 IL23R	2.31e-05	3	97	2	28878115
Pubmed	Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor.	STAT3 IL23R	2.31e-05	3	97	2	23673666
Pubmed	Dietary cholesterol reduces plasma triacylglycerol in apolipoprotein E-null mice: suppression of lipin-1 and -2 in the glycerol-3-phosphate pathway.	LPIN1 LPIN2	2.31e-05	3	97	2	21857965
Pubmed	CD5 costimulation induces stable Th17 development by promoting IL-23R expression and sustained STAT3 activation.	STAT3 IL23R	2.31e-05	3	97	2	21926348
Pubmed	Investigation of IL23R, JAK2, and STAT3 gene polymorphisms and gene-gene interactions in Crohn's disease and ulcerative colitis in a Turkish population.	STAT3 IL23R	2.31e-05	3	97	2	27852544
Pubmed	The ETS factor ESE3/EHF represses IL-6 preventing STAT3 activation and expansion of the prostate cancer stem-like compartment.	STAT3 EHF	2.31e-05	3	97	2	27732936
Pubmed	Functional Redundancy of Cyclase-Associated Proteins CAP1 and CAP2 in Differentiating Neurons.	CAP2 CAP1	2.31e-05	3	97	2	34204261
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	NDST1 MAN2A1 MARCHF6 CRELD2 RNF213 MBOAT2 GTF3C3 GPR107 ATRIP LRP4 SEC63 USP48 PCYOX1	2.95e-05	1201	97	13	35696571
Pubmed	Molecular reclassification of Crohn's disease by cluster analysis of genetic variants.	STAT3 DNAH12 IL23R	3.58e-05	23	97	3	20886065
Pubmed	Phosphorylated STAT3 and PD-1 regulate IL-17 production and IL-23 receptor expression in Mycobacterium tuberculosis infection.	STAT3 IL23R	4.60e-05	4	97	2	24643836
Pubmed	Profound defects in pupillary responses to light in TRPM-channel null mice: a role for TRPM channels in non-image-forming photoreception.	TRPM3 TRPM1	4.60e-05	4	97	2	22211741
Pubmed	Stimulation of peripheral kappa opioid receptors inhibits inflammatory hyperalgesia via activation of the PI3Kγ/AKT/nNOS/NO signaling pathway.	PIK3CG NOS1	4.60e-05	4	97	2	22316281
Pubmed	Lipin 2 is a liver-enriched phosphatidate phosphohydrolase enzyme that is dynamically regulated by fasting and obesity in mice.	LPIN1 LPIN2	4.60e-05	4	97	2	19136718
Pubmed	Shikonin-mediated PD-L1 degradation suppresses immune evasion in pancreatic cancer by inhibiting NF-κB/STAT3 and NF-κB/CSN5 signaling pathways.	STAT3 COPS5	4.60e-05	4	97	2	33707115
Pubmed	Micropuncture analysis of tubuloglomerular feedback regulation in transgenic mice.	ACE NOS1	4.60e-05	4	97	2	10589702
Pubmed	Retinoic acid-induced nNOS expression depends on a novel PI3K/Akt/DAX1 pathway in human TGW-nu-I neuroblastoma cells.	PIK3CG NOS1	4.60e-05	4	97	2	19726747
Pubmed	The sequence of the human genome.	RNF213 CCDC168 CHRNB4 SH3PXD2B CFAP54 DNAH12 ATRIP DNAH17 ERCC6L2	4.92e-05	603	97	9	11181995
Pubmed	Genetic risk profiling and prediction of disease course in Crohn's disease patients.	STAT3 DNAH12 IL23R	6.55e-05	28	97	3	19422935
Pubmed	Expression of angiogenic regulators, VEGF and leptin, is regulated by the EGF/PI3K/STAT3 pathway in colorectal cancer cells.	STAT3 PIK3CG	7.66e-05	5	97	2	19492417
Pubmed	c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont.	STAT3 IL23R	7.66e-05	5	97	2	29414937
Pubmed	Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A.	GPR107 TMEM87B	7.66e-05	5	97	2	36373655
Pubmed	Artesunate inhibits adipogeneis in 3T3-L1 preadipocytes by reducing the expression and/or phosphorylation levels of C/EBP-α, PPAR-γ, FAS, perilipin A, and STAT-3.	STAT3 PLIN2	7.66e-05	5	97	2	27109481
Pubmed	Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation.	STAT3 IL23R	7.66e-05	5	97	2	27524624
Pubmed	Mammalian adenylyl cyclase family members are randomly located on different chromosomes.	ADCY4 ADCY1	7.66e-05	5	97	2	7959689
Pubmed	Differing roles of mitochondrial nitric oxide synthase in cardiomyocytes and urothelial cells.	NOS1 SOD2	7.66e-05	5	97	2	14684357
Pubmed	STAT3 down-regulates the expression of cyclin D during liver development.	TDO2 STAT3	1.15e-04	6	97	2	12147685
Pubmed	Macrophage-derived CCL5 facilitates immune escape of colorectal cancer cells via the p65/STAT3-CSN5-PD-L1 pathway.	STAT3 COPS5	1.15e-04	6	97	2	31802034
Pubmed	An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses.	STAT3 IL23R	1.15e-04	6	97	2	26411290
Pubmed	Mapping of adenylyl cyclase genes type I, II, III, IV, V, and VI in mouse.	ADCY4 ADCY1	1.15e-04	6	97	2	7766992
Pubmed	Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland.	ADCY4 ADCY1	1.15e-04	6	97	2	11549699
Pubmed	Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells.	STAT3 IL23R	1.15e-04	6	97	2	26750311
Pubmed	Mammalian CAP interacts with CAP, CAP2, and actin.	CAP2 CAP1	1.15e-04	6	97	2	8761950
Pubmed	Association of STAT3 and TNFRSF1A with ankylosing spondylitis in Han Chinese.	STAT3 IL23R	1.15e-04	6	97	2	21068102
Pubmed	Identification of type 2 diabetes-associated combination of SNPs using support vector machine.	ACE PIGF CAP1 SOD2	1.26e-04	91	97	4	20416077
Pubmed	Evidence for an association between haptoglobin and MnSOD (Val9Ala) gene polymorphisms in essential hypertension based on a Brazilian case-control study.	ACE SOD2	1.60e-04	7	97	2	21053180
Pubmed	CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module.	DNAH17 DNAH11	1.60e-04	7	97	2	33139725
Pubmed	Gene polymorphisms against DNA damage induced by hydrogen peroxide in leukocytes of healthy humans through comet assay: a quasi-experimental study.	ACE SOD2	1.60e-04	7	97	2	20444272
Pubmed	Evaluation of gene polymorphisms in exercise-induced oxidative stress and damage.	ACE SOD2	1.60e-04	7	97	2	20109103
Pubmed	Differential expression of adenylyl cyclase mRNAs in lacrimal glands of NZB/NZW and NOD pre-autoimmune mice.	ADCY4 ADCY1	1.60e-04	7	97	2	12613887
Pubmed	Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes.	STAT3 IL23R	1.60e-04	7	97	2	34433045
Pubmed	A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R.	STAT3 IL23R	1.60e-04	7	97	2	12023369
Pubmed	The actin-binding protein CAP1 represses MRTF-SRF-dependent gene expression in mouse cerebral cortex.	CAP2 CAP1	1.60e-04	7	97	2	38713765
Pubmed	Crisp1 and alopecia areata in C3H/HeJ mice.	LYST SGK3	2.13e-04	8	97	2	25446841
Pubmed	Differentiating inbred mouse strains from each other and those with single gene mutations using hair proteomics.	LYST SGK3	2.13e-04	8	97	2	23251662
Pubmed	Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86.	EHF ELF3	2.13e-04	8	97	2	15075319
Pubmed	Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.	ADCY4 ADCY1	2.74e-04	9	97	2	9417641
Pubmed	Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.	ADCY4 ADCY1	2.74e-04	9	97	2	12503609
Pubmed	Role of the calcium modulated cyclases in the development of the retinal projections.	ADCY4 ADCY1	2.74e-04	9	97	2	17229090
Pubmed	Transcriptome analysis of human gastric cancer.	PHF19 HGSNAT SGK3 EHF PWP2 SEC63 USP48 CAP1 MGME1	3.13e-04	772	97	9	16341674
Pubmed	ZBED evolution: repeated utilization of DNA transposons as regulators of diverse host functions.	ZBED10P ZBED6	3.41e-04	10	97	2	23533661
Pubmed	Mechanism of human immunodeficiency virus-induced complement expression in astrocytes and neurons.	ADCY4 ADCY1	3.41e-04	10	97	2	11884542
Pubmed	Purification and characterization of a soluble form of mammalian adenylyl cyclase.	ADCY4 ADCY1	3.41e-04	10	97	2	8663304
Pubmed	Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.	ADCY4 ADCY1	3.41e-04	10	97	2	16615126
Interaction	LPIN2 interactions	LPIN3 LPIN1 FBXW8 LPIN2	4.58e-06	24	95	4	int:LPIN2
Cytoband	2p25.1	MBOAT2 LPIN1 SLC66A3	2.03e-05	25	97	3	2p25.1
GeneFamily	Dyneins, axonemal	DNAH7 DNAH12 DNAH17 DNAH8 DNAH11	2.84e-09	17	64	5	536
GeneFamily	Lipins	LPIN3 LPIN1 LPIN2	4.23e-08	3	64	3	1043
GeneFamily	Adenylate cyclases\|Deafness associated genes	ADCY4 ADCY1	5.45e-04	10	64	2	53
GeneFamily	WD repeat domain containing	DYNC2I1 LYST FBXW8 PWP2 CFAP44	2.34e-03	262	64	5	362
GeneFamily	ETS transcription factor family	EHF ELF3	4.39e-03	28	64	2	534
GeneFamily	Transient receptor potential cation channels	TRPM3 TRPM1	4.39e-03	28	64	2	249
Coexpression	KAYO_AGING_MUSCLE_DN	MARCHF6 LPIN1 CKMT2 PIGF MED12 SOD2	6.50e-06	124	96	6	M17261
Coexpression	GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_DN	MAN2A1 PHF19 HGSNAT PLXNC1 TMEM87B CENPI PCYOX1	9.10e-06	200	96	7	M8048
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	MAN2A1 RNF213 SFI1 LYST LPIN1 ZBED6 IL23R	1.15e-07	177	96	7	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	DNAH7 CFAP54 DNAH12 EHF ELF3 CFAP44 DNAH11	2.30e-07	196	96	7	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 DNAH7 CFAP54 DNAH12 SYNE2 CFAP44 DNAH11	2.38e-07	197	96	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	MAN2A1 RNF213 SFI1 LYST LPIN1 ZBED6	2.28e-06	176	96	6	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	MAN2A1 RNF213 SFI1 STAT3 ZNF10 SYNE2	3.76e-06	192	96	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK3 RAPGEF5 DNAH7 CFAP54 EHF ELF3	3.76e-06	192	96	6	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DYNC2I1 DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	3.88e-06	193	96	6	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DYNC2I1 DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	3.99e-06	194	96	6	b4ce60c06568123008b1081d644733cb91c28f51
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	DNAH7 CFAP54 DNAH12 ELF3 CFAP44 DNAH11	3.99e-06	194	96	6	958e648138676d46698090b4046cb484083ae449
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DYNC2I1 DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	3.99e-06	194	96	6	7a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell	ASK452-Epithelial-Ciliated\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH7 DNAH12 EHF ELF3 CFAP44 DNAH11	3.99e-06	194	96	6	5aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	3.99e-06	194	96	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH7 CFAP54 DNAH12 SYNE2 ELF3 DNAH11	4.11e-06	195	96	6	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	4.11e-06	195	96	6	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	DNAH7 CFAP54 DNAH12 SYNE2 ELF3 DNAH11	4.11e-06	195	96	6	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH7 CFAP54 DNAH12 SYNE2 ELF3 DNAH11	4.11e-06	195	96	6	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	4.11e-06	195	96	6	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	4.11e-06	195	96	6	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	DYNC2I1 DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	4.24e-06	196	96	6	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH7 CFAP54 DNAH12 SYNE2 ELF3 DNAH11	4.24e-06	196	96	6	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH7 CFAP54 DNAH12 SYNE2 ELF3 DNAH11	4.24e-06	196	96	6	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DYNC2I1 DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	4.36e-06	197	96	6	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	DNAH7 CFAP54 DNAH12 EHF DNAH11	1.90e-05	151	96	5	8216462e723fec2797387929dde095370947e10a
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH7 CFAP54 SLC24A4 CFAP44 DNAH11	2.09e-05	154	96	5	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH7 CFAP54 SLC24A4 CFAP44 DNAH11	2.09e-05	154	96	5	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	SHQ1 TRPM3 DNAH17 FAM169A ELF3	2.44e-05	159	96	5	f34f2729a3872fbb2939e76ad35d7e25f71b8f57
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal-Unfolded_protein_responsible_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	SHQ1 TRPM3 DNAH17 FAM169A ELF3	2.44e-05	159	96	5	929ed98f6c2ad14e8d5af5c6f11a5a3d4b388cf7
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BEST1 ACE LYST CRNKL1 SMPDL3B	2.67e-05	162	96	5	93bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK3 DNAH7 CFAP54 EHF ELF3	2.91e-05	165	96	5	0c714e852f912b5749de4cb0895406673979b2e6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK3 DNAH7 CFAP54 EHF ELF3	2.91e-05	165	96	5	82530f96aaefe28a13bad0474bbad043f127a86c
ToppCell	Ciliated_cells-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	3.00e-05	166	96	5	4b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	3.09e-05	167	96	5	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 DNAH7 CFAP54 DNAH12 DNAH11	3.27e-05	169	96	5	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	3.27e-05	169	96	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4\|TCGA-Lung / Sample_Type by Project: Shred V9	MAN2A1 RNF213 MBOAT2 SAMD9L PLXNC1	3.97e-05	176	96	5	0923b01137d6f9956ca815b41102c81e82624065
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	3.97e-05	176	96	5	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs\|normal_Pleural_Fluid / Location, Cell class and cell subclass	PLIN2 FBXW8 CFAP54 PIGF TGFBRAP1	3.97e-05	176	96	5	7a74217b7fa1032b918f00a3972dff5fab74671a
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPGEF5 LYST SAMD9L ZBED6 SYNE2	4.19e-05	178	96	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADCY4 RAPGEF5 ACE PIK3CG NOS1	4.19e-05	178	96	5	c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 DNAH7 CFAP54 DNAH12 DNAH11	4.30e-05	179	96	5	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 DNAH7 DNAH12 CFAP44 DNAH11	4.41e-05	180	96	5	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	EHF LPIN2 FAM169A LRP4 ELF3	4.41e-05	180	96	5	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	4.41e-05	180	96	5	92fb01b91261b3103454924cde56add337b41844
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH7 LPIN1 CFAP54 EHF DNAH11	4.53e-05	181	96	5	6a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	MAN2A1 RNF213 SFI1 ZNF10 SYNE2	4.53e-05	181	96	5	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	4.65e-05	182	96	5	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ADCY4 RAPGEF5 ACE ADCY1 NOS1	4.90e-05	184	96	5	a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	5.03e-05	185	96	5	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	5.16e-05	186	96	5	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 RAPGEF5 LYST SAMD9L SYNE2	5.16e-05	186	96	5	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH7 CFAP54 TRPM3 SYNE2 DNAH11	5.16e-05	186	96	5	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	DOCK3 KLHL24 ANO5 CKMT2 CAP2	5.29e-05	187	96	5	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ADCY4 RAPGEF5 ACE ADCY1 NOS1	5.43e-05	188	96	5	366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	MARCHF6 RNF213 ZNF10 ZBED6 SYNE2	5.43e-05	188	96	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Control-Epithelial-Ciliated\|Control / Disease state, Lineage and Cell class	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	5.56e-05	189	96	5	c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	5.56e-05	189	96	5	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ADCY4 RAPGEF5 ACE ADCY1 PIK3CG	5.70e-05	190	96	5	7ba2be2630183df86de21689289a8620a4cd507e
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK3 DNAH7 CFAP54 EHF ELF3	5.85e-05	191	96	5	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	5.99e-05	192	96	5	be592e661367affced9ebe80849b466e6adb3a34
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	DOCK3 KLHL24 ANO5 CKMT2 CAP2	5.99e-05	192	96	5	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	IPF-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	5.99e-05	192	96	5	d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCell	COPD-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	5.99e-05	192	96	5	eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell	IPF-Epithelial-Ciliated\|IPF / Disease state, Lineage and Cell class	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	5.99e-05	192	96	5	354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell	ASK452-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH7 DNAH12 EHF CFAP44 DNAH11	6.14e-05	193	96	5	c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.14e-05	193	96	5	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DYNC2I1 DNAH7 CFAP54 CFAP44 DNAH11	6.14e-05	193	96	5	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.14e-05	193	96	5	0b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell	ASK440-Epithelial-Ciliated\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.14e-05	193	96	5	a0baa8be6f590b2031fede22be588715ae458e93
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.30e-05	194	96	5	756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell	droplet-Bladder-nan-24m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLIN2 EHF LPIN2 ELF3 LAS1L	6.30e-05	194	96	5	c48de3b9c281345c8f65427703837dd921b01826
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PHF19 ANO5 SH3PXD2B TRAM1L1 MGME1	6.30e-05	194	96	5	0e9830ad070c47acaa952400bf2a3ddbff664a2f
ToppCell	ASK440-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.30e-05	194	96	5	c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.30e-05	194	96	5	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	medial-Hematologic-Nonclassical_Monocyte\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PHF19 LYST SLC24A4 PLXNC1 PIK3CG	6.30e-05	194	96	5	ac203d388a3a3884e316dec0dcbd408e43c6ef6c
ToppCell	medial-2-Hematologic-Nonclassical_Monocyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PHF19 LYST SLC24A4 PLXNC1 PIK3CG	6.30e-05	194	96	5	202e5070728191c46161fa7d931f00be1c7559d4
ToppCell	medial-Hematologic-Nonclassical_Monocyte-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PHF19 LYST SLC24A4 PLXNC1 PIK3CG	6.30e-05	194	96	5	002cd317732fc6b0d9a72fb46199f71db5a638a7
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK3 DNAH7 CFAP54 EHF ELF3	6.30e-05	194	96	5	6b286992d4bb56013c0ea5a7601d3476d806175a
ToppCell	wk_15-18-Epithelial-Proximal_epithelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DNAH7 DNAH12 EHF CFAP44 DNAH11	6.30e-05	194	96	5	b0477583301dc6d9767b667bd2f8f94fbfaa6f81
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK3 DNAH7 CFAP54 EHF ELF3	6.30e-05	194	96	5	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.30e-05	194	96	5	a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 DNAH7 DNAH12 CFAP44 DNAH11	6.45e-05	195	96	5	d211a836cf711fdb91b10d512f09d462be937cc5
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.45e-05	195	96	5	0e763f36786515698b593e5c93f6a56619c1242d
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.45e-05	195	96	5	581b04220587e1d5198b1abd6965965ace7803e7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.45e-05	195	96	5	93b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.45e-05	195	96	5	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.45e-05	195	96	5	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.45e-05	195	96	5	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	critical-Epithelial-Ciliated\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.61e-05	196	96	5	27b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH7 DNAH12 ELF3 CFAP44 DNAH11	6.61e-05	196	96	5	686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DNAH7 DNAH12 ELF3 CFAP44 DNAH11	6.61e-05	196	96	5	67aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH7 DNAH12 ELF3 CFAP44 DNAH11	6.61e-05	196	96	5	ca56311edc6788e032e7635fa69b1e07035202b5
ToppCell	Severe_COVID-19-Epithelial-Ciliated\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	DNAH7 DNAH12 ELF3 CFAP44 DNAH11	6.61e-05	196	96	5	1cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCell	distal-3-Hematologic-Nonclassical_Monocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PHF19 LYST SLC24A4 PLXNC1 PIK3CG	6.61e-05	196	96	5	c1f3334bc09f5d0cfb9d998a3a64f0700426a357
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.61e-05	196	96	5	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH7 DNAH12 ELF3 CFAP44 DNAH11	6.61e-05	196	96	5	69f5081e06d84ec1d9695762df801a9d0df1984b
ToppCell	PBMC-Control-cDC_3\|Control / Compartment, Disease Groups and Clusters	HGSNAT PLXNC1 ZBED6 PIK3CG CAP1	6.61e-05	196	96	5	09d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH7 CFAP54 DNAH12 CFAP44 DNAH11	6.77e-05	197	96	5	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 DNAH7 DNAH12 CFAP44 DNAH11	6.77e-05	197	96	5	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 DNAH7 DNAH12 CFAP44 DNAH11	6.77e-05	197	96	5	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	Bronchial_Brush-Epithelial\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH12 SYNE2 EHF ELF3 DNAH11	6.77e-05	197	96	5	272c7f4e582ef57564450540242b0db766b78328
Disease	myoglobinuria (implicated_via_orthology)	LPIN3 LPIN1 LPIN2	2.74e-08	3	90	3	DOID:0080108 (implicated_via_orthology)
Disease	lipid metabolism disorder (implicated_via_orthology)	LPIN3 LPIN1 LPIN2	1.22e-05	15	90	3	DOID:3146 (implicated_via_orthology)
Disease	obesity (implicated_via_orthology)	STAT3 PLIN2 LPIN3 LPIN1 LPIN2 MED12	5.22e-05	215	90	6	DOID:9970 (implicated_via_orthology)
Disease	Fever	STAT3 NOS1 SOD2	7.61e-05	27	90	3	C0015967
Disease	Amphetamine-Related Disorders	RAPGEF5 TRPM3 USP48 NOS1	8.34e-05	75	90	4	C0236733
Disease	Amphetamine Abuse	RAPGEF5 TRPM3 USP48 NOS1	8.34e-05	75	90	4	C0236807
Disease	Amphetamine Addiction	RAPGEF5 TRPM3 USP48 NOS1	8.34e-05	75	90	4	C0236804
Disease	Lung diseases	ACE STAT3 SOD2 DNAH11	9.71e-05	78	90	4	C0024115
Disease	Microvascular complications of diabetes, susceptibility	ACE SOD2	1.37e-04	6	90	2	cv:CN357508
Disease	Behcet's disease (is_implicated_in)	ACE STAT3 IL23R	1.82e-04	36	90	3	DOID:13241 (is_implicated_in)
Disease	MASA syndrome (implicated_via_orthology)	TRPM3 TRPM1	1.91e-04	7	90	2	DOID:0060246 (implicated_via_orthology)
Disease	Spastic Paraplegia	LYST RAB3GAP2	3.27e-04	9	90	2	C0037772
Disease	Oxidative Phosphorylation Deficiencies	SOD2 MGME1	3.27e-04	9	90	2	C0949856
Disease	Mitochondrial Respiratory Chain Deficiencies	SOD2 MGME1	3.27e-04	9	90	2	C0949857
Disease	Electron Transport Chain Deficiencies, Mitochondrial	SOD2 MGME1	3.27e-04	9	90	2	C0949855
Disease	abdominal aortic aneurysm (implicated_via_orthology)	ACE EHF	3.27e-04	9	90	2	DOID:7693 (implicated_via_orthology)
Disease	Fibrosis	STAT3 PIK3CG SOD2	4.85e-04	50	90	3	C0016059
Disease	Cirrhosis	STAT3 PIK3CG SOD2	4.85e-04	50	90	3	C1623038
Disease	Seizures	GTF3C3 CHRNB4 TRPM3 NOS1 SOD2	5.55e-04	218	90	5	C0036572
Disease	IGFBP-1 measurement	ANO5 TGFBRAP1	7.02e-04	13	90	2	EFO_0005118
Disease	Psoriasis	STAT3 IL23R SOD2	7.13e-04	57	90	3	C0033860
Disease	Pustulosis of Palms and Soles	STAT3 IL23R SOD2	7.13e-04	57	90	3	C0030246
Disease	Brain Ischemia	ACE STAT3 SOD2	8.28e-04	60	90	3	C0007786
Disease	Cerebral Ischemia	ACE STAT3 SOD2	8.28e-04	60	90	3	C0917798
Disease	Major Depressive Disorder	RAPGEF5 TDO2 ACE MED12 SOD2	9.04e-04	243	90	5	C1269683
Disease	sarcoidosis (is_implicated_in)	ACE IL23R	1.07e-03	16	90	2	DOID:11335 (is_implicated_in)
Disease	attention function measurement	ANO5 TDO2 CHRNB4 PLIN2	1.11e-03	148	90	4	EFO_0007636
Disease	Unipolar Depression	RAPGEF5 TDO2 ACE NOS1 MED12	1.20e-03	259	90	5	C0041696
Disease	Eye Abnormalities	NDST1 SH3PXD2B	1.21e-03	17	90	2	C0015393
Disease	Psychoses, Substance-Induced	ACE SOD2	1.21e-03	17	90	2	C0033941
Disease	sphingomyelin 14:0 measurement	TRPM3 SYNE2	1.21e-03	17	90	2	EFO_0010390
Disease	ulcerative colitis (is_implicated_in)	STAT3 IL23R	1.21e-03	17	90	2	DOID:8577 (is_implicated_in)
Disease	ankylosing spondylitis (is_implicated_in)	ACE IL23R	1.52e-03	19	90	2	DOID:7147 (is_implicated_in)
Disease	renovascular hypertension (biomarker_via_orthology)	ACE NOS1	1.52e-03	19	90	2	DOID:1591 (biomarker_via_orthology)
Disease	lung cancer (is_implicated_in)	ACE CHRNB4 SOD2	1.52e-03	74	90	3	DOID:1324 (is_implicated_in)
Disease	end stage renal disease (implicated_via_orthology)	ACE NOS1	1.69e-03	20	90	2	DOID:783 (implicated_via_orthology)
Disease	Psychoses, Drug	ACE SOD2	1.86e-03	21	90	2	C0033937
Disease	Depressive disorder	ACE STAT3 NOS1 MED12 SOD2	1.94e-03	289	90	5	C0011581
Disease	depressive symptom measurement	UBE3B LPIN3 SYNE2 LRP4 NOS1 MED12	1.96e-03	426	90	6	EFO_0007006
Disease	Cardiomegaly	STAT3 PIK3CG SOD2	2.04e-03	82	90	3	C0018800
Disease	Cardiac Hypertrophy	STAT3 PIK3CG SOD2	2.04e-03	82	90	3	C1383860
Disease	age at menopause	SH3PXD2B PIK3CG TGFBRAP1 MED12 SOD2	2.35e-03	302	90	5	EFO_0004704
Disease	Coronary heart disease	ACE DNAH11	2.43e-03	24	90	2	C0010068
Disease	HDL cholesterol change measurement	MBOAT2 SYNE2	2.43e-03	24	90	2	EFO_0007805
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	ACE SOD2	2.43e-03	24	90	2	DOID:3827 (biomarker_via_orthology)
Disease	Albuminuria	ACE SOD2	2.43e-03	24	90	2	C0001925
Disease	Lymphatic Metastasis	STAT3 SOD2	2.85e-03	26	90	2	C0024232
Disease	systemic scleroderma, systemic lupus erythematosus	SAMD9L EHF	2.85e-03	26	90	2	EFO_0000717, MONDO_0007915

Protein segments in the cluster

Peptide	Gene	Start	Entry
TTNVWLKQEWTDYRL	CHRNB4	76	P30926
KLLELLWNKYWVNTL	COPS5	236	Q92905
NKWIYLLWQINEVIH	CFAP54	641	Q96N23
NIKEAIYPLALNWWR	ANO5	626	Q75V66
ITKENYNQEWWSLRL	ACE	1081	P12821
DWVKAYLSIWTELQA	CAP1	181	Q01518
EIWSLNKEVRVWDAY	DNAH11	1366	Q96DT5
LQKWQYDVWSHDVTL	ADCY4	381	Q8NFM4
FWSKTQVLDWISYQV	ELF3	66	P78545
VTLVVTRWWNQYENL	BEST1	86	O76090
WEKLQYLWKSTLNLP	AASDH	556	Q4L235
DYTLTIWNWKEEQPI	CFAP44	251	Q96MT7
SYLEIWENDWLKKEV	CCDC83	211	Q8IWF9
VLIVFIYDEQIVWWE	SLC24A4	216	Q8NFF2
IYDEQIVWWEGLVLI	SLC24A4	221	Q8NFF2
FQWKWLYQLLDETAT	GPR107	521	Q5VW38
WEALSLDTEYWKLLL	RAB3GAP2	876	Q9H2M9
IYLWKWDDKVVISDI	LPIN3	631	Q9BQK8
VYWKLRKLLTQEWVQ	MAGEA8	241	P43361
WNIQTALWLKRVCYE	MBOAT2	341	Q6ZWT7
ISYLSKWWDIIDIQK	MAN2A1	216	Q16706
QYWTKWLLRLEEYTE	MGME1	316	Q9BQP7
WPENLLSYIDELVWQ	ERVFC1-1	31	P60608
YNQIAELWKPWLSNE	SMPDL3B	151	Q92485
LLDSKYVLCVWDIWQ	DYNC2I1	671	Q8WVS4
HVDWVKSYLNIWSEL	CAP2	181	P40123
WKVIAEDEVLWYRLC	FBXW8	146	Q8N3Y1
SNWFIINVIKLVWRY	PCYOX1	131	Q9UHG3
LYTLNEDWLLWQVPE	PLXNC1	1181	O60486
DIIEEWLVVQNLWVY	DNAH8	1486	Q96JB1
WLVVQNLWVYLEAVF	DNAH8	1491	Q96JB1
TIDEWLKVQAQWLYL	DNAH12	901	Q6ZR08
VQLYEAWKQVWSIRV	NDST1	441	P52848
YLWNWDDKVIISDID	LPIN1	666	Q14693
PQWWLKTVIEQVYAN	MARCHF6	781	O60337
VLDWLQKTYWCRQLE	LAS1L	176	Q9Y4W2
WTQIITKYLWEQLQK	MED12	186	Q93074
LVLSKGLQEYEEWKW	NOS1	1131	P29475
LRKWQYDVWSNDVTL	ADCY1	411	Q08828
VISNWIKYAQWEESL	CRNKL1	241	Q9BZJ0
DVWIYNSQLNIWIRV	KLHL24	376	Q6TFL4
ATLQEWASLWKQLYV	DOCK3	91	Q8IZD9
DQLVDYRVEFSKWWI	DNAH17	2366	Q9UFH2
TKYQVWEWLQHLLDT	EHF	51	Q9NZC4
ILDEWLKVQATWLYL	DNAH7	976	Q8WXX0
IQWDAVIALYILFSW	IL23R	6	Q5VWK5
LTAVALYLADQWWAI	FAM169A	76	Q9Y6X4
LYLADQWWAIDDIVK	FAM169A	81	Q9Y6X4
LLWKWDALKAYQNFV	LYST	686	Q99698
IHNELLWTNLTVYWK	HGSNAT	86	Q68CP4
QWLQLEQEVVWLLAK	ATRIP	651	Q8WXE1
WIIQNDWVAIFFIIL	CCDC168	31	Q8NDH2
PLSVLYNWKDELDTW	ERCC6L2	216	Q5T890
WLSQTLQEECIWYKV	CENPI	391	Q92674
LEAWWLQLKSEYPDL	CRELD2	101	Q6UXH1
EVIRKQPYDNTVDWW	SGK3	331	Q96BR1
IWHNYDKTFLIWINE	CKMT2	251	P17540
VGLLWVLVLNWYATE	TAS2R46	56	P59540
AWSQWREQLLYVQKE	SFI1	256	A8K8P3
ELEEWYTWLDNALVL	TRPC4AP	321	Q8TEL6
IEETWRLWQKFLDDY	SYNE2	6131	Q8WXH0
HQAYELWFKQILWEL	TDO2	76	P48775
VKNWNAWTALETYLQ	TCAF1	821	Q9Y4C2
VISPLWIYWNRKQLT	PIGF	201	Q07326
WNKLFDWIQSELYVR	RGPD2	146	P0DJD1
WEKISTLNLYQQPSW	SAMD9L	481	Q8IVG5
DTLGQVYKSEIKWWL	SAMD9L	1121	Q8IVG5
VSQWIALYKDWLPED	RAPGEF5	151	Q92565
NAKTVEWDWKLLTYV	SIMC1	541	Q8NDZ2
DEAIEQILKYNPWWT	SHQ1	206	Q6PI26
NTIVAWVLWYLLNSF	SLC6A18	116	Q96N87
TKDDWWNLLLKAIYS	GTF3C3	621	Q9Y5Q9
EEVLWNVWLEFSIKI	PIK3CG	406	P48736
FSWKIKDYLEELWVQ	RNF213	3711	Q63HN8
LVWAYADWVLQKSEE	TGFBRAP1	541	Q8WUH2
TIQAYVTWNLITLWL	TRAM1L1	306	Q8N609
LVWEWQSESYVLKQQ	PWP2	356	Q15269
EVIEKNLSGWWYIQI	SH3PXD2B	396	A1X283
FWVWLDNIIDLVKKY	STAT3	561	P40763
WLQEYWNVTDLIAIL	TRPM3	961	Q9HCF6
QELWELVLKRWIEDY	TTC41P	566	Q6P2S7
LVLKRWIEDYSWTFQ	TTC41P	571	Q6P2S7
WASIIVKKYLWENET	ZBED10P	191	Q96FA7
EWEWLNLAQRSLYKK	ZNF470	36	Q6ECI4
LVTFEDNSKYWVLWK	PHF19	71	Q5T6S3
WWLYIADRKEQTLIS	SEC63	651	Q9UGP8
VRPDYLKAIWNVINW	SOD2	196	P04179
VSSWFILALQKWIID	SLC66A3	101	Q8N755
QRWVQYLLLLQESIW	SNX19	871	Q92543
YPWQLLEEIWKVNFT	TAS1R2	416	Q8TE23
IKVWLQEYWNITDLV	TRPM1	891	Q7Z4N2
LWYLSLEEVWKCRDQ	ZNF10	121	P21506
YWKDILRIQFWIAAV	TMEM87B	241	Q96K49
LTLLWIQQIKNILWY	UBE3B	126	Q7Z3V4
IYWQRKISIWPALTQ	ZBED6	886	P86452
LKYLSNQELSCWQIW	ZNF227	106	Q86WZ6
DAQDKLYLSWVEWKR	PLIN2	276	Q99541
IDLAVYETLKNWWLQ	SLC25A23	351	Q9BV35
YEFVSLEWLQKWLDE	USP48	486	Q86UV5
LYFSEQEWEILEKWQ	ZNF425	16	Q6IV72
LAIDWVTNKLYWTDA	LRP4	821	O75096
IYLWNWNDKIIISDI	LPIN2	676	Q92539