Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRG PTPRR

4.48e-0517122GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRG PTPRR

4.48e-0517122GO:0019198
GeneOntologyMolecularFunctionphospholipid binding

GRB7 MME ARAP2 AXL

2.33e-04548124GO:0005543
GeneOntologyMolecularFunctionphosphatidylserine binding

MME AXL

8.50e-0473122GO:0001786
GeneOntologyMolecularFunctionprotein tyrosine phosphatase activity

PTPRG PTPRR

1.68e-03103122GO:0004725
GeneOntologyMolecularFunctionlipid binding

GRB7 MME ARAP2 AXL

2.14e-03988124GO:0008289
GeneOntologyMolecularFunctionmodified amino acid binding

MME AXL

2.35e-03122122GO:0072341
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

MCM8 BPTF

2.54e-03127122GO:0008094
GeneOntologyMolecularFunctionphosphoprotein phosphatase activity

PTPRG PTPRR

5.53e-03189122GO:0004721
GeneOntologyBiologicalProcessregulation of homophilic cell adhesion

PTPRG PTPRR

3.94e-0518112GO:1903385
DomainPTPc

PTPRG PTPRR

2.36e-0436122SM00194
DomainRA

GRB7 ARAP2

2.36e-0436122PF00788
DomainRA

GRB7 ARAP2

2.49e-0437122PS50200
DomainTYR_PHOSPHATASE_PTP

PTPRG PTPRR

2.77e-0439122PS50055
DomainRA_dom

GRB7 ARAP2

2.91e-0440122IPR000159
DomainPTPase_domain

PTPRG PTPRR

3.06e-0441122IPR000242
DomainY_phosphatase

PTPRG PTPRR

3.06e-0441122PF00102
DomainTyr_Pase_cat

PTPRG PTPRR

6.34e-0459122IPR003595
DomainPTPc_motif

PTPRG PTPRR

6.34e-0459122SM00404
DomainTyr_Pase_AS

PTPRG PTPRR

9.70e-0473122IPR016130
DomainTYR_PHOSPHATASE_1

PTPRG PTPRR

1.34e-0386122PS00383
DomainTYR_PHOSPHATASE_2

PTPRG PTPRR

1.37e-0387122PS50056
DomainTYR_PHOSPHATASE_dom

PTPRG PTPRR

1.37e-0387122IPR000387
Domain-

PTPRG PTPRR

1.53e-03921223.90.190.10
DomainProt-tyrosine_phosphatase-like

PTPRG PTPRR

1.77e-0399122IPR029021
Domainfn3

PTPRG AXL

4.66e-03162122PF00041
DomainFN3

PTPRG AXL

6.03e-03185122SM00060
DomainFN3

PTPRG AXL

6.95e-03199122PS50853
DomainFN3_dom

PTPRG AXL

7.64e-03209122IPR003961
DomainPH

GRB7 ARAP2

9.11e-03229122PF00169
DomainPH

GRB7 ARAP2

1.32e-02278122SM00233
DomainPH_DOMAIN

GRB7 ARAP2

1.33e-02279122PS50003
DomainPH_domain

GRB7 ARAP2

1.34e-02280122IPR001849
Domain-

GRB7 ARAP2

2.51e-023911222.30.29.30
Pubmed

The tumour suppressor OPCML promotes AXL inactivation by the phosphatase PTPRG in ovarian cancer.

PTPRG AXL

3.27e-07312229907679
Pubmed

Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'.

PTPRG PTPRR

1.64e-06612221724833
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PTPRG MCM8 MME PTPRR BPTF FAM120A

4.51e-06148912628611215
Pubmed

Receptor protein tyrosine phosphatases are expressed by cycling retinal progenitor cells and involved in neuronal development of mouse retina.

PTPRG PTPRR

1.31e-051612218308476
Pubmed

Protein tyrosine phosphatases expression during development of mouse superior colliculus.

PTPRG PTPRR

1.48e-051712219727691
Pubmed

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

PTPRG PTPRR

1.17e-044712219167335
InteractionMRPS25 interactions

MCM8 MME FAM120A AXL

1.41e-05269124int:MRPS25
InteractionMRPS34 interactions

GRB7 PTPRR FAM120A AXL

2.69e-05317124int:MRPS34
InteractionMRPS7 interactions

GRB7 PTPRR FAM120A AXL

4.19e-05355124int:MRPS7
InteractionRPL39P5 interactions

GRB7 AXL

1.31e-0429122int:RPL39P5
InteractionZNF784 interactions

TRAF4 BPTF

1.50e-0431122int:ZNF784
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRG PTPRR

7.02e-0521112813
GeneFamilyFibronectin type III domain containing

PTPRG AXL

4.06e-03160112555
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

GRB7 ARAP2

6.64e-03206112682
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

PTPRG CFHR3 AXL

1.37e-051811232b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_2|343B / Donor, Lineage, Cell class and subclass (all cells)

MME FKBP15 AXL

1.59e-051901236514f00d222eef08c282face7f177259bca62f0e
ToppCellSevere_COVID-19-Myeloid-proliferating_Myeloid_cells|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

MCM8 MME AXL

1.66e-051931230d85025690c9cd545cba30abc38acbdd6a39b153
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MCM8 MME AXL

1.69e-05194123903ae11708b0cb24538c6982abd57fe6fa95b8d3
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MCM8 MME AXL

1.69e-05194123cb39850e9577015b6b9834e98c36b412bae7d462
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MCM8 MME AXL

1.69e-05194123408597c9aa302a44b112c1d612c21fbb0227a82a
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MCM8 MME AXL

1.69e-05194123193cc20fefbd795a4ad59e401a95af47d30603e7
ToppCellBAL-Severe-Myeloid-Myeloid|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MCM8 MME AXL

1.69e-051941232360b5f995b360419de41612368cab9fb61781a1
ToppCellBAL-Severe-Myeloid-Myeloid|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MCM8 MME AXL

1.69e-0519412358406502a8cbcc3037f79a1b6a683df408297ae5
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Airway-Club|LPS_only / Treatment groups by lineage, cell group, cell type

GRB7 MME PTPRR

1.82e-05199123165ac94b2d56072ad43358b5127d77555221e2d8
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRB7 MME

4.96e-041251225626eb77e542fcc87cd1fdf65f8623f3249ff9db
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

GRB7 MME

5.04e-04126122730fc6dc740613b55e40e85334fa30330aa81c3b
ToppCellControl-Neutrophil|Control / Disease condition and Cell class

GRB7 MME

5.04e-04126122450c01d89714feee6529680ec3ce69067a54b37c
ToppCellControl-Neutrophil-|Control / Disease condition and Cell class

GRB7 MME

5.04e-0412612265fff5ec2296272e94f44546606587833191dd82
ToppCellControl-Myeloid_G-Neutrophil|Control / Disease group, lineage and cell class

GRB7 MME

5.12e-04127122d4af23d621b546785a077c367c3a66c59749fc15
ToppCellPBMC-Control-Myeloid-Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

GRB7 MME

5.28e-041291225578a9ef85706ab6a204ff31716e781ec3893b75
ToppCellPBMC-Control-Myeloid-Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GRB7 MME

5.37e-04130122124f76067a2d4448ce06158a769d0d11b0297110
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GRB7 MME

5.37e-04130122cd6d8d646345b01ff0f04f776330a05b82e63bc9
ToppCellControl-Myeloid_G|Control / Disease group, lineage and cell class

GRB7 MME

5.45e-04131122d5a53431f1f1b283fb9338b8561e6381f0227c62
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_3|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

GRB7 ARAP2

5.87e-041361225e209185b5f6e9347829fc9066f0b2c3711df057
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MME PTPRR

6.13e-041391229e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GRB7 MME

6.39e-04142122191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GRB7 MME

6.48e-04143122b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRAF4 MME

7.22e-04151122c06a54afe918b14f885d6a85fbcf81e80f33afae
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRG CFHR3

7.42e-041531221524557514668f515ac1bbe847611f564b265b42
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PTPRG ARAP2

7.71e-041561226c8f442ed94ae31e6832b68137e98ae78091ac6c
ToppCellPBMC-Mild-cDC_3|Mild / Compartment, Disease Groups and Clusters

GRB7 MME

7.90e-041581225fefab4831687cd8dd45f5cc84f681398069c3be
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPRG ARAP2

8.10e-041601228e2b51d7b42e0b6e62641efdbbc73d31561d6a3e
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRG MME

8.10e-04160122c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRG MME

8.10e-0416012225c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

PTPRG TRAF4

8.41e-04163122e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellLPS_only-Epithelial_airway-Club_cells-Airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MME PTPRR

8.51e-04164122b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCellLPS_only-Epithelial_airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MME PTPRR

8.51e-0416412256e6934e6c7503a300d7be06762d45a1d6f1ae0f
ToppCellLPS_only-Epithelial_airway-Club_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MME PTPRR

8.51e-04164122c5b2001280a43da855017361a3f6071a0e492848
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MME PTPRR

8.51e-041641224ade97931ae1780af7836d988fe117a10b3e88a1
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells-CLP|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MME ARAP2

8.51e-04164122f5cacd7b2329cb0c7c1696eb4d8f89a4bbd9dda1
ToppCellLPS-IL1RA-Epithelial_airway-Club_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MME PTPRR

8.61e-041651221a114eacaab598f755a173a3fed842ba91f689dd
ToppCellLPS-IL1RA-Epithelial_airway-Club_cells-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MME PTPRR

8.61e-041651229cfd3c1d2c6d714fde83b90465f1f9741b0e50ce
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MME PTPRR

8.72e-041661221df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MME PTPRR

8.72e-041661229628522e7af8f8edca733588a364ab2454ac5ca5
ToppCellLPS-antiTNF-Epithelial_airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MME PTPRR

8.72e-04166122eb942ed68677e55c46cb039046f45686d4062d7c
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

TRAF4 AXL

8.82e-04167122bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCellmild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

TRAF4 AXL

8.93e-04168122968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MCM8 AXL

8.93e-04168122a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

PTPRG AXL

9.03e-041691226373562ab3b1765060212a6a53d6543e7e942e80
ToppCell356C-Epithelial_cells-Epithelial-D_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MME AXL

9.03e-04169122818ab7a6fd1940a22d3bd99fe15f0af888af6b3e
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Club_cells-Airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MME PTPRR

9.03e-0416912286041be5d3aeab5b9269f7912791b944f325a1b4
ToppCell356C-Epithelial_cells-Epithelial-D_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MME AXL

9.03e-04169122f982f2e0d341fa27229f443ebe5c0e4a9e63bda6
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Club_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MME PTPRR

9.03e-041691228c96e1baa38ec5e777e627ab9dbce025e771f2c0
ToppCell10x5'-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

TRAF4 AXL

9.14e-0417012259cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCellCOVID-19_Convalescent-cDC|COVID-19_Convalescent / Disease condition and Cell class

TRAF4 AXL

9.24e-041711229ccaa9f1629818b0f63a5d930ee78c01e04cd98d
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRG PTPRR

9.24e-041711221597459c971d6befa991d59dc66b41b6a522f797
ToppCellCOVID_vent-Lymphocytic-Dendritic-pDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

TRAF4 AXL

9.24e-04171122779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCellCOVID-19_Convalescent-cDC-|COVID-19_Convalescent / Disease condition and Cell class

TRAF4 AXL

9.24e-04171122fb5fae8b3adafcbb7c5618d887966b418355ed4d
ToppCellCOVID_vent-Lymphocytic-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

TRAF4 AXL

9.24e-04171122debbb071d260639b16269c94d172766908325c58
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

TRAF4 AXL

9.24e-0417112272c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCellImmune_cells-pro-B|Immune_cells / Lineage and Cell class

TRAF4 GRB7

9.35e-04172122096636f2589fa56d15942aac96641c16fd5fa78d
ToppCellCOVID-pDC|COVID / Condition, Cell_class and T cell subcluster

TRAF4 MME

9.35e-041721223ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCellsevere_influenza-B_memory|World / disease group, cell group and cell class (v2)

TRAF4 GRB7

9.35e-041721220ff38f9431cec73250c580a6010cb7891a3fe3f1
ToppCellCOVID-pDC-|COVID / Condition, Cell_class and T cell subcluster

TRAF4 MME

9.35e-04172122a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
ToppCelldroplet-Lung-LUNG-1m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCM8 AXL

9.46e-0417312269b404e92aad3e6dff67e75466f073f20a71f13f
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCM8 AXL

9.46e-0417312226bba58f9fb215d1d155504906cd77e8774f6936
ToppCellImmune_cells-pro-B|World / Lineage and Cell class

TRAF4 GRB7

9.57e-04174122e173adbf5789dfa20f3cbc668efde5f0992ac219
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PTPRG AXL

9.68e-041751221125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCell(00)_Basal-(2)_48hpi|(00)_Basal / shred by cell type and Timepoint

GRB7 FAM120A

9.79e-041761220f6770296d7fa453ffbf6ca6d5fdebc888f6eb60
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac-Macrophage|GI_small-bowel / Manually curated celltypes from each tissue

MME CFHR3

9.79e-041761224be270f6bb7da4070f972aca403109751646d155
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MME PTPRR

9.90e-04177122a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MCM8 AXL

9.90e-04177122cbedac0bddb8fc330a464815c905928c553b0fc0
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MME PTPRR

9.90e-04177122363e07b0f347f3716d530a28ead854b98e27d37c
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MME AXL

1.00e-031781220b398656f26c4061b11ccf98908d0e2e1367585a
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRG PTPRR

1.00e-03178122ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MCM8 AXL

1.00e-0317812204bfecf5ea5d85c843e48d08718b5d69e7bf834e
ToppCellCOPD-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

PTPRG PTPRR

1.01e-031791229968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MCM8 TRAF4

1.01e-031791229dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCellCOPD-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

PTPRG PTPRR

1.01e-03179122e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-B_memory-0|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRAF4 MME

1.01e-03179122fce1ba53815145f6248d4e90aedca3dad84e33e4
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

PTPRG AXL

1.01e-03179122dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellmild-Myeloid-pDC|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TRAF4 AXL

1.02e-0318012238614155fa537d0defda914c531c697be0ef06d8
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MCM8 FKBP15

1.02e-0318012262511d76d24b836839c3dcc2bf30485ffe9401e2
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRB7 AXL

1.02e-0318012243fd5c498a87bb078d101298b472656f3294686a
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRG CFHR3

1.03e-03181122ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCellControl-Epithelial_alveolar-AT_1-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRB7 MME

1.05e-03182122a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCelldroplet-Lung-nan-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRB7 MME

1.05e-03182122cfba75c1ffc39ac76db9e8e27394731942882b30
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MCM8 AXL

1.05e-0318212221dcab170ffeef89faa9fee5008568cb6e15c694
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRAF4 PTPRR

1.05e-03182122215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TRAF4 MME

1.05e-031821229bbe8062aa562dc3b9c299581faf6ebbcb72a9f7
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TRAF4 MME

1.05e-031821224602a98df7045e2c70b7560abfba9b444fbd5d30
ToppCelldroplet-Lung-nan-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRB7 MME

1.05e-031821227e7c7a26460d3003cdf0c0ffb96208a566aa09a7
ToppCelldroplet-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRB7 MME

1.05e-03182122d836bfdc298ecd3558a973e393a329eb8bd59d79
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MCM8 FKBP15

1.05e-0318212203992d0ae519795239e4f2cc8e63f33c4482de6a
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MME AXL

1.06e-03183122103c4c4595d8daa677679fd2fa1e99cd398e56dd
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GRB7 AXL

1.06e-03183122e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCellControl-Endothelial_cells-Pulmonary_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

PTPRG PTPRR

1.06e-0318312246be9f96755c7b65aeac061d95d15abeb6466034
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

MME ARAP2

1.06e-03183122f593a89b0aa8fffdfa403769916facfd30358521
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

PTPRG PTPRR

1.07e-031841220f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TRAF4 AXL

1.07e-0318412223c24ab5786af33d605bc445d06117b9da6c6331
ToppCellCOPD-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

MME AXL

1.07e-031841227fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCellCOPD-Endothelial-VE_Venous|COPD / Disease state, Lineage and Cell class

PTPRG PTPRR

1.07e-0318412244d716e7ba46a1ed03f5992631289653f8fd7d5e
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TRAF4 AXL

1.08e-03185122b1e84228c95be8ccf7c3c1afb66b71ffb93cf61e
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|metastatic_Brain / Location, Cell class and cell subclass

PTPRG PTPRR

1.08e-03185122ad52970e88e8947ef256095bd4b40229b912d58a
DrugTyr-Phe

MME AXL

2.66e-0515122CID003421919
DrugGallamine triethiodide [65-29-2]; Down 200; 4.4uM; PC3; HT_HG-U133A

TRAF4 PTPRR BPTF

1.33e-041971232059_DN
DrugAztreonam [78110-38-0]; Up 200; 9.2uM; PC3; HT_HG-U133A

TRAF4 GRB7 AXL

1.35e-041981232118_UP
DrugCytisine (-) [485-35-8]; Up 200; 21uM; MCF7; HT_HG-U133A

PTPRG GRB7 FKBP15

1.37e-041991236217_UP
Drugmeprobamate

PTPRG MME

9.51e-0488122CID000004064
DrugAC1L1K12

MME CFHR3

1.27e-03102122CID000005292
Drugaspartate

MME PTPRR FKBP15

2.21e-03518123CID000000424
Drugnickel

MME ARAP2 AXL

2.65e-03552123CID000000934
DrugMebendazole [31431-39-7]; Up 200; 13.6uM; HL60; HT_HG-U133A

ARAP2 AXL

3.02e-031581222338_UP
Drugn-butoxyethanol

TRAF4 ARAP2 AXL

3.06e-03581123ctd:C017096
Diseaseinfluenza A (H1N1)

ARAP2 PTPRR

5.56e-0487122EFO_1001488
DiseaseUterine leiomyoma

MCM8 PTPRR

6.08e-0491122HP_0000131
Diseasewellbeing measurement

PTPRG PTPRR BPTF

2.41e-03692123EFO_0007869
Diseaseuterine fibroid

MCM8 PTPRR

2.86e-03199122EFO_0000731
Diseasemetabolic syndrome

ARAP2 BPTF

2.89e-03200122EFO_0000195
Diseasepost-traumatic stress disorder

BPTF FAM120A

2.94e-03202122EFO_0001358
Diseaseaspartate aminotransferase measurement

PTPRR CFHR3 AXL

5.13e-03904123EFO_0004736
Diseaseserum gamma-glutamyl transferase measurement

ARAP2 BPTF AXL

5.29e-03914123EFO_0004532
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

PTPRG BPTF

9.23e-03364122EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946

Protein segments in the cluster

PeptideGeneStartEntry
YINANYVDGYNKAKA

PTPRG

906

P23470
QYGLGCKYIYQKNGD

ARAP2

1141

Q8WZ64
KLGQEGKYRVYHNQY

BPTF

841

Q12830
QLKNVRANYYGKYIA

MCM8

206

Q9UJA3
HAYRYTNGQYVKQGK

FKBP15

81

Q5T1M5
GQAYRAYQNYIKKNG

MME

656

P08473
GRYYGRGYKNQAAIQ

FAM120A

1001

Q9NZB2
FKYGVQLYKNYQQAQ

GRB7

336

Q14451
YINANYIRGYSGKEK

PTPRR

446

Q15256
YLENGYNQNYGRKFV

CFHR3

91

Q02985
KIYNGDYYRQGRIAK

AXL

696

P30530
KYGYKLQVSAFLNGN

TRAF4

341

Q9BUZ4
GNSKMKACNNYQYGY

nan

96

Q8IYB0