Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

CLIC4 GJA5 GJB2 ATP6V0A1 PIEZO2 CTNS ABCD2 SLC41A3 ATP2A1 TMC3 CLIC2 SLC18A1 SLC23A2 ABCA12 SLC2A11

1.46e-0911803815GO:0022857
GeneOntologyMolecularFunctiontransporter activity

CLIC4 GJA5 GJB2 ATP6V0A1 PIEZO2 CTNS ABCD2 SLC41A3 ATP2A1 TMC3 CLIC2 SLC18A1 SLC23A2 ABCA12 SLC2A11

4.90e-0912893815GO:0005215
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CLIC4 ATP6V0A1 PIEZO2 CTNS SLC41A3 ATP2A1 TMC3 CLIC2 SLC18A1 SLC23A2

1.59e-067933810GO:0015075
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ATP6V0A1 CTNS ABCD2 SLC41A3 ATP2A1 SLC18A1 SLC23A2 ABCA12

2.60e-06477388GO:0022804
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

ATP6V0A1 CTNS SLC41A3 ATP2A1 SLC18A1 SLC23A2

2.05e-05301386GO:0022853
GeneOntologyMolecularFunctionscavenger receptor binding

FPR1 FPR2

3.51e-055382GO:0005124
GeneOntologyMolecularFunctionN-formyl peptide receptor activity

FPR1 FPR2

3.51e-055382GO:0004982
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP6V0A1 ABCD2 ATP2A1 ABCA12

5.37e-05109384GO:0042626
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CLIC4 ATP6V0A1 CTNS SLC41A3 ATP2A1 CLIC2 SLC18A1 SLC23A2

7.39e-05758388GO:0015318
GeneOntologyMolecularFunctiongap junction channel activity involved in cell communication by electrical coupling

GJA5 GJB2

1.26e-049382GO:1903763
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

ATP6V0A1 PIEZO2 CTNS SLC41A3 ATP2A1 SLC18A1 SLC23A2

2.24e-04664387GO:0008324
GeneOntologyMolecularFunctioncomplement receptor activity

FPR1 FPR2

3.16e-0414382GO:0004875
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ATP6V0A1 ABCD2 ATP2A1 ABCA12

3.56e-04178384GO:0015399
GeneOntologyMolecularFunctionRAGE receptor binding

FPR1 FPR2

3.65e-0415382GO:0050786
GeneOntologyMolecularFunctionchannel activity

CLIC4 GJA5 GJB2 PIEZO2 TMC3 CLIC2

4.33e-04525386GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CLIC4 GJA5 GJB2 PIEZO2 TMC3 CLIC2

4.38e-04526386GO:0022803
GeneOntologyMolecularFunctionmechanosensitive monoatomic ion channel activity

PIEZO2 TMC3

5.29e-0418382GO:0008381
GeneOntologyMolecularFunctiongap junction channel activity

GJA5 GJB2

1.03e-0325382GO:0005243
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

ATP6V0A1 CTNS SLC41A3 ATP2A1 SLC18A1 SLC23A2

1.10e-03627386GO:0022890
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC23A2 SLC2A11

1.20e-0327382GO:0015145
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC23A2 SLC2A11

1.39e-0329382GO:0051119
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

CTNS SLC18A1 SLC23A2

1.50e-03119383GO:0015294
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

CLIC4 CLIC2 SLC18A1

1.72e-03125383GO:0015108
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

SSTR2 FPR1 FPR2

2.06e-03133383GO:0008528
GeneOntologyMolecularFunctionwide pore channel activity

GJA5 GJB2

2.25e-0337382GO:0022829
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

CTNS SLC41A3 SLC18A1 SLC23A2

2.35e-03296384GO:0015291
GeneOntologyMolecularFunctionpeptide receptor activity

SSTR2 FPR1 FPR2

2.38e-03140383GO:0001653
GeneOntologyMolecularFunctionsymporter activity

CTNS SLC18A1 SLC23A2

2.89e-03150383GO:0015293
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC23A2 SLC2A11

2.89e-0342382GO:0015144
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

CLIC4 CLIC2 SLC18A1

2.95e-03151383GO:0008509
GeneOntologyMolecularFunctionimmune receptor activity

IL20RB FPR1 FPR2

3.78e-03165383GO:0140375
GeneOntologyMolecularFunctionABC-type transporter activity

ABCD2 ABCA12

3.92e-0349382GO:0140359
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

CLIC4 CLIC2 SLC18A1

4.18e-03171383GO:0015103
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC41A3 SLC18A1 SLC23A2

4.18e-03171383GO:0015081
GeneOntologyMolecularFunctionintramolecular oxidoreductase activity

PIGK EBP

5.27e-0357382GO:0016860
GeneOntologyMolecularFunctionproton transmembrane transporter activity

ATP6V0A1 CTNS SLC18A1

5.44e-03188383GO:0015078
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP6V0A1 ATP2A1

6.21e-0362382GO:0019829
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

CTNS ABCD2 SLC23A2

7.09e-03207383GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

CTNS ABCD2 SLC23A2

7.19e-03208383GO:0005342
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCD2 ABCA12

8.51e-0373382GO:0170055
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC18A1 SLC23A2

1.04e-0281382GO:0015370
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CLIC4 PIEZO2 TMC3 CLIC2

1.10e-02459384GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC41A3 ATP2A1 SLC18A1 SLC23A2

1.15e-02465384GO:0046873
GeneOntologyMolecularFunctioncysteine-type endopeptidase activity

CTSK PIGK

1.17e-0286382GO:0004197
GeneOntologyMolecularFunctionchloride channel activity

CLIC4 CLIC2

1.17e-0286382GO:0005254
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR1E2 TMIGD3 IL20RB SSTR2 CD300E FPR1 FPR2

1.28e-021353387GO:0004888
GeneOntologyMolecularFunctionmonoatomic anion channel activity

CLIC4 CLIC2

1.64e-02103382GO:0005253
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

CTNS ABCD2 SLC23A2

1.81e-02293383GO:0008514
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CLIC4 ATP6V0A1 PIEZO2 CTNS SLC41A3 ATP2A1 TMC3 CLIC2 SLC18A1 SLC23A2 AP3D1

5.95e-0611154011GO:0034220
GeneOntologyBiologicalProcessmonoatomic ion transport

CLIC4 GJA5 ATP6V0A1 PIEZO2 CTNS SLC41A3 ATP2A1 TMC3 CLIC2 SLC18A1 SLC23A2 AP3D1

7.07e-0613744012GO:0006811
GeneOntologyBiologicalProcessmonoatomic cation transport

GJA5 ATP6V0A1 PIEZO2 CTNS SLC41A3 ATP2A1 CLIC2 SLC18A1 SLC23A2 AP3D1

5.36e-0511574010GO:0006812
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

ATP6V0A1 PIEZO2 CTNS SLC41A3 ATP2A1 CLIC2 SLC18A1 SLC23A2 AP3D1

6.33e-05942409GO:0098655
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

CLIC4 ATP6V0A1 CTNS SLC41A3 ATP2A1 CLIC2 SLC18A1 SLC23A2 AP3D1

1.14e-041017409GO:0098660
GeneOntologyBiologicalProcessregulation of heart contraction

TMIGD3 GJA5 ATP2A1 CLIC2 TMEM161B

1.15e-04249405GO:0008016
GeneOntologyCellularComponentsecretory granule membrane

ATP6V0A1 ITGA2B SLC18A1 ABCA12 VPS13B FPR1 FPR2

2.68e-06329407GO:0030667
GeneOntologyCellularComponentcytoplasmic vesicle membrane

AP5M1 CLIC4 ATP6V0A1 CTNS ITGA2B ZDHHC17 SLC18A1 ABCA12 AP3D1 VPS13B FPR1 FPR2

3.68e-0613074012GO:0030659
GeneOntologyCellularComponentvesicle membrane

AP5M1 CLIC4 ATP6V0A1 CTNS ITGA2B ZDHHC17 SLC18A1 ABCA12 AP3D1 VPS13B FPR1 FPR2

4.24e-0613254012GO:0012506
GeneOntologyCellularComponentmembrane protein complex

AP5M1 CLIC4 GJA5 GJB2 ATP6V0A1 ITGA2B ATP2A1 CLIC2 PIGK TMEM249 AP3D1

8.19e-0514984011GO:0098796
GeneOntologyCellularComponentficolin-1-rich granule membrane

ATP6V0A1 FPR1 FPR2

2.16e-0461403GO:0101003
GeneOntologyCellularComponentlysosomal membrane

AP5M1 ATP6V0A1 CTNS AP3D1 VPS13B FPR1

2.29e-04462406GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

AP5M1 ATP6V0A1 CTNS AP3D1 VPS13B FPR1

2.29e-04462406GO:0098852
GeneOntologyCellularComponentvacuolar membrane

AP5M1 ATP6V0A1 CTNS AP3D1 VPS13B FPR1

3.77e-04507406GO:0005774
GeneOntologyCellularComponentlysosome

AP5M1 ATP6V0A1 CTNS CTSK AP3D1 VPS13B FPR1

7.85e-04811407GO:0005764
GeneOntologyCellularComponentlytic vacuole

AP5M1 ATP6V0A1 CTNS CTSK AP3D1 VPS13B FPR1

7.85e-04811407GO:0000323
GeneOntologyCellularComponentconnexin complex

GJA5 GJB2

8.05e-0422402GO:0005922
GeneOntologyCellularComponentvacuole

AP5M1 ATP6V0A1 CTNS CTSK AP3D1 VPS13B FPR1

1.56e-03913407GO:0005773
GeneOntologyCellularComponentgap junction

GJA5 GJB2

2.28e-0337402GO:0005921
GeneOntologyCellularComponentsecretory granule

ATP6V0A1 ITGA2B SLC18A1 ABCA12 VPS13B FPR1 FPR2

2.83e-031014407GO:0030141
GeneOntologyCellularComponenttransmembrane transporter complex

CLIC4 ATP6V0A1 ATP2A1 CLIC2 TMEM249

3.07e-03523405GO:1902495
GeneOntologyCellularComponenttertiary granule

ATP6V0A1 FPR1 FPR2

3.79e-03164403GO:0070820
GeneOntologyCellularComponenttransporter complex

CLIC4 ATP6V0A1 ATP2A1 CLIC2 TMEM249

3.81e-03550405GO:1990351
GeneOntologyCellularComponentAP-type membrane coat adaptor complex

AP5M1 AP3D1

3.81e-0348402GO:0030119
GeneOntologyCellularComponentficolin-1-rich granule

ATP6V0A1 FPR1 FPR2

5.30e-03185403GO:0101002
GeneOntologyCellularComponentchloride channel complex

CLIC4 CLIC2

5.33e-0357402GO:0034707
GeneOntologyCellularComponentnuclear inner membrane

DPY19L4 LEMD2

5.70e-0359402GO:0005637
GeneOntologyCellularComponentmonoatomic ion channel complex

CLIC4 ATP2A1 CLIC2 TMEM249

5.76e-03378404GO:0034702
GeneOntologyCellularComponentpresynapse

TMIGD3 ATP6V0A1 ZDHHC17 TENM3 SLC18A1 AP3D1

6.38e-03886406GO:0098793
DomainCLIC

CLIC4 CLIC2

6.02e-056382IPR002946
DomainFormyl_rcpt-rel

FPR1 FPR2

1.80e-0410382IPR000826
DomainCONNEXINS_1

GJA5 GJB2

6.74e-0419382PS00407
DomainConnexin_N

GJA5 GJB2

7.48e-0420382IPR013092
DomainCONNEXINS_2

GJA5 GJB2

7.48e-0420382PS00408
DomainConnexin

GJA5 GJB2

7.48e-0420382PF00029
DomainConnexin_CCC

GJA5 GJB2

7.48e-0420382SM01089
DomainConnexin_CS

GJA5 GJB2

7.48e-0420382IPR017990
DomainConnexin

GJA5 GJB2

7.48e-0420382IPR000500
DomainConnexin_CCC

GJA5 GJB2

7.48e-0420382IPR019570
DomainCNX

GJA5 GJB2

7.48e-0420382SM00037
DomainGST_CTER

CLIC4 CLIC2

2.17e-0334382PS50405
DomainGlutathione-S-Trfase_C-like

CLIC4 CLIC2

2.85e-0339382IPR010987
Domain-

CLIC4 CLIC2

2.85e-03393821.20.1050.10
DomainABC_transporter_CS

ABCD2 ABCA12

3.30e-0342382IPR017871
DomainABC_TRANSPORTER_2

ABCD2 ABCA12

4.29e-0348382PS50893
DomainABC_tran

ABCD2 ABCA12

4.29e-0348382PF00005
DomainABC_TRANSPORTER_1

ABCD2 ABCA12

4.46e-0349382PS00211
DomainABC_transporter-like

ABCD2 ABCA12

4.64e-0350382IPR003439
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP6V0A1 CTNS ABCD2 ATP2A1 CLIC2 SLC18A1 ABCA12 SLC2A11

3.58e-05736268M27287
PathwayKEGG_LYSOSOME

ATP6V0A1 CTNS CTSK AP3D1

6.67e-05121264M11266
PathwayREACTOME_FORMYL_PEPTIDE_RECEPTORS_BIND_FORMYL_PEPTIDES_AND_MANY_OTHER_LIGANDS

FPR1 FPR2

9.10e-058262MM15110
PathwayREACTOME_FORMYL_PEPTIDE_RECEPTORS_BIND_FORMYL_PEPTIDES_AND_MANY_OTHER_LIGANDS

FPR1 FPR2

9.10e-058262M27370
PathwayWP_GPCRS_PEPTIDE

SSTR2 FPR1 FPR2

2.81e-0470263MM15959
PathwayWP_PEPTIDE_GPCRS

SSTR2 FPR1 FPR2

3.44e-0475263M39696
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

TMIGD3 SSTR2 FPR1 FPR2

3.50e-04186264MM15994
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCD2 ABCA12

4.37e-0417262MM14552
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCD2 ABCA12

4.91e-0418262M524
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

OR1E2 SSTR2 FPR1 FPR2

1.23e-03260264M39397
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP6V0A1 CTNS ABCD2 ATP2A1 SLC18A1 ABCA12

1.25e-03681266MM14985
PathwayREACTOME_GAP_JUNCTION_ASSEMBLY

GJA5 GJB2

1.57e-0332262MM14730
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

TMIGD3 SSTR2 FPR1 FPR2

1.81e-03289264MM15057
PathwayREACTOME_GAP_JUNCTION_ASSEMBLY

GJA5 GJB2

2.21e-0338262M14981
Pubmed

Proresolving and tissue-protective actions of annexin A1-based cleavage-resistant peptides are mediated by formyl peptide receptor 2/lipoxin A4 receptor.

FPR1 FPR2

1.29e-06240223686496
Pubmed

Expression and function of formyl peptide receptors on human fibroblast cells.

FPR1 FPR2

1.29e-06240212902510
Pubmed

Stimulation of human formyl peptide receptors by calpain inhibitors: homology modeling of receptors and ligand docking simulation.

FPR1 FPR2

1.29e-06240222005393
Pubmed

N-formylpeptides induce two distinct concentration optima for mouse neutrophil chemotaxis by differential interaction with two N-formylpeptide receptor (FPR) subtypes. Molecular characterization of FPR2, a second mouse neutrophil FPR.

FPR1 FPR2

1.29e-06240210477558
Pubmed

Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2.

FPR1 FPR2

1.29e-06240235217703
Pubmed

Formyl peptide receptors promotes neural differentiation in mouse neural stem cells by ROS generation and regulation of PI3K-AKT signaling.

FPR1 FPR2

1.29e-06240228303030
Pubmed

The non-steroidal anti-inflammatory drug piroxicam blocks ligand binding to the formyl peptide receptor but not the formyl peptide receptor like 1.

FPR1 FPR2

1.29e-06240217692291
Pubmed

A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family.

FPR1 FPR2

1.29e-0624021373134
Pubmed

Mitocryptide-2: Identification of Its Minimum Structure for Specific Activation of FPR2-Possible Receptor Switching from FPR2 to FPR1 by Its Physiological C-terminal Cleavages.

FPR1 FPR2

1.29e-06240233920954
Pubmed

Formylpeptide receptors mediate rapid neutrophil mobilization to accelerate wound healing.

FPR1 FPR2

1.29e-06240224603667
Pubmed

The two neutrophil members of the formylpeptide receptor family activate the NADPH-oxidase through signals that differ in sensitivity to a gelsolin derived phosphoinositide-binding peptide.

FPR1 FPR2

1.29e-06240215625007
Pubmed

Differential expression of the G-protein-coupled formyl Peptide receptor in melanoma associates with aggressive phenotype.

FPR1 FPR2

1.29e-06240223147350
Pubmed

The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor loop.

FPR1 FPR2

1.29e-06240223562731
Pubmed

A neutrophil inhibitory pepducin derived from FPR1 expected to target FPR1 signaling hijacks the closely related FPR2 instead.

FPR1 FPR2

1.29e-06240226071379
Pubmed

Functional expression of N-formyl peptide receptors in human bone marrow-derived mesenchymal stem cells.

FPR1 FPR2

1.29e-06240217234990
Pubmed

Lack of formyl peptide receptor 1 and 2 leads to more severe inflammation and higher mortality in mice with of pneumococcal meningitis.

FPR1 FPR2

1.29e-06240224863484
Pubmed

A Critical Role of Formyl Peptide Receptors in Host Defense against Escherichia coli.

FPR1 FPR2

1.29e-06240232221037
Pubmed

Formylpeptide receptors are critical for rapid neutrophil mobilization in host defense against Listeria monocytogenes.

FPR1 FPR2

1.29e-06240223139859
Pubmed

G-protein-coupled formyl peptide receptors play a dual role in neutrophil chemotaxis and bacterial phagocytosis.

FPR1 FPR2

1.29e-06240230540534
Pubmed

Deficiency of formyl peptide receptor 1 and 2 is associated with increased inflammation and enhanced liver injury after LPS-stimulation.

FPR1 FPR2

1.29e-06240224956481
Pubmed

Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.

GJB2 PIEZO2 ABCD2

3.18e-062540335681537
Pubmed

The annexin A1/FPR2 signaling axis expands alveolar macrophages, limits viral replication, and attenuates pathogenesis in the murine influenza A virus infection model.

FPR1 FPR2

3.87e-06340231398292
Pubmed

Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE)--and amyloid beta 1-42-induced signal transduction in glial cells.

FPR1 FPR2

3.87e-06340223164356
Pubmed

Breast cancer metastasis to brain results in recruitment and activation of microglia through annexin-A1/formyl peptide receptor signaling.

FPR1 FPR2

3.87e-06340235382852
Pubmed

Formylpeptide receptor-2 contributes to colonic epithelial homeostasis, inflammation, and tumorigenesis.

FPR1 FPR2

3.87e-06340223454745
Pubmed

Identification of FAM3D as a new endogenous chemotaxis agonist for the formyl peptide receptors.

FPR1 FPR2

3.87e-06340226966188
Pubmed

Formyl peptide receptors from immune and vomeronasal system exhibit distinct agonist properties.

FPR1 FPR2

3.87e-06340222859307
Pubmed

The Two Formyl Peptide Receptors Differently Regulate GPR84-Mediated Neutrophil NADPH Oxidase Activity.

FPR1 FPR2

3.87e-06340233789297
Pubmed

Identification, cloning, and functional characterization of a murine lipoxin A4 receptor homologue gene.

FPR1 FPR2

3.87e-06340212218158
Pubmed

Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4.

FPR1 FPR2

3.87e-06340212410796
Pubmed

Amyloid-beta induces chemotaxis and oxidant stress by acting at formylpeptide receptor 2, a G protein-coupled receptor expressed in phagocytes and brain.

FPR1 FPR2

3.87e-06340211316806
Pubmed

Formyl peptide receptor 2 is an emerging modulator of inflammation in the liver.

FPR1 FPR2

3.87e-06340236750693
Pubmed

Annexin-1 signals mitogen-stimulated breast tumor cell proliferation by activation of the formyl peptide receptors (FPRs) 1 and 2.

FPR1 FPR2

3.87e-06340220930115
Pubmed

Characterization of two new members of the formyl peptide receptor gene family from 129S6 mice.

FPR1 FPR2

3.87e-06340212459252
Pubmed

Formyl peptide receptor-like 2 is expressed and functional in plasmacytoid dendritic cells, tissue-specific macrophage subpopulations, and eosinophils.

FPR1 FPR2

3.87e-06340219342677
Pubmed

Annexin A1/Formyl Peptide Receptor Pathway Controls Uterine Receptivity to the Blastocyst.

FPR1 FPR2

3.87e-06340232403233
Pubmed

Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ.

FPR1 FPR2

3.87e-06340219497865
Pubmed

Functional expression of formyl peptide receptor family in human NK cells.

FPR1 FPR2

3.87e-06340219843937
Pubmed

Formyl peptide receptor 1 up-regulation and formyl peptide receptor 2/3 down-regulation of blood immune cells along with defective lipoxin A4/resolvin D1 production in obstructive sleep apnea patients.

FPR1 FPR2

3.87e-06340231116781
Pubmed

Annexin A1 regulates hormone exocytosis through a mechanism involving actin reorganization.

FPR1 FPR2

3.87e-06340219625660
Pubmed

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family.

FPR1 FPR2

3.87e-06340219498085
Pubmed

Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19.

FPR1 FPR2

7.73e-0644021612600
Pubmed

The N-formylpeptide receptor (FPR) and a second G(i)-coupled receptor mediate fMet-Leu-Phe-stimulated activation of NADPH oxidase in murine neutrophils.

FPR1 FPR2

7.73e-06440212470609
Pubmed

Neutrophils discriminate live from dead bacteria by integrating signals initiated by Fprs and TLRs.

FPR1 FPR2

7.73e-06440235112724
Pubmed

Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms.

FPR1 FPR2

7.73e-06440212560218
Pubmed

An annexin 1 N-terminal peptide activates leukocytes by triggering different members of the formyl peptide receptor family.

FPR1 FPR2

7.73e-06440215187149
Pubmed

Differential expression of the gap junction proteins connexin45, -43, -40, -31, and -26 in mouse skin.

GJA5 GJB2

1.29e-0554027889986
Pubmed

Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis.

FPR1 FPR2

1.29e-05540226606969
Pubmed

Role of connexin (gap junction) genes in cell growth control and carcinogenesis.

GJA5 GJB2

1.93e-05640210196667
Pubmed

Genetic diseases and gene knockouts reveal diverse connexin functions.

GJA5 GJB2

2.70e-05740210099690
Pubmed

Transplacental uptake of glucose is decreased in embryonic lethal connexin26-deficient mice.

GJA5 GJB2

2.70e-0574029508777
Pubmed

Expression of the gap junction proteins connexin31 and connexin43 correlates with communication compartments in extraembryonic tissues and in the gastrulating mouse embryo, respectively.

GJA5 GJB2

2.70e-0574028834803
Pubmed

Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set.

IL20RB PIEZO2 ZDHHC17 VPS13B

3.22e-0515740412466305
Pubmed

NFATC1 promotes epicardium-derived cell invasion into myocardium.

GJA5 CTSK

3.60e-05840221447555
Pubmed

Diverse functions of vertebrate gap junctions.

GJA5 GJB2

3.60e-0584029861669
Pubmed

Neutrophil-derived cathelicidin promotes adhesion of classical monocytes.

FPR1 FPR2

3.60e-05840223283724
Pubmed

Chromosomal assignments of mouse connexin genes, coding for gap junctional proteins, by somatic cell hybridization.

GJA5 GJB2

3.60e-0584021332196
Pubmed

Differential expansion of the N-formylpeptide receptor gene cluster in human and mouse.

FPR1 FPR2

4.62e-0594029722950
Pubmed

Cx31 and Cx43 double-deficient mice reveal independent functions in murine placental and skin development.

GJA5 GJB2

4.62e-05940215895417
Pubmed

Gap junctions in the inner ear: comparison of distribution patterns in different vertebrates and assessement of connexin composition in mammals.

GJA5 GJB2

4.62e-05940214595769
Pubmed

Expression of connexins in embryonic mouse neocortical development.

GJA5 GJB2

5.77e-051040217640036
Pubmed

Adhesion molecule CADM1 contributes to gap junctional communication among pancreatic islet α-cells and prevents their excessive secretion of glucagon.

GJA5 GJB2

5.77e-051040222513384
Pubmed

Multiple members of the connexin gene family participate in preimplantation development of the mouse.

GJA5 GJB2

7.05e-05114028631157
Pubmed

mRNA expression pattern of multiple members of connexin gene family in normal and abnormal fetal gonads in mouse.

GJA5 GJB2

7.05e-051140215255617
Pubmed

Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides.

FPR1 FPR2

8.45e-051240232294408
Pubmed

Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.

ATP6V0A1 SLC18A1

8.45e-051240220038947
Pubmed

DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon.

PIEZO2 SSTR2

1.34e-041540237541195
Pubmed

Compartmentalized metabolism supports midgestation mammalian development.

GJA5 GJB2

1.73e-041740235388219
Pubmed

An expression atlas of connexin genes in the mouse.

GJA5 GJB2

1.95e-041840215081111
Pubmed

The novel mouse connexin39 gene is expressed in developing striated muscle fibers.

GJA5 GJB2

1.95e-041840215466892
Pubmed

An update on connexin genes and their nomenclature in mouse and man.

GJA5 GJB2

2.18e-041940214681012
Pubmed

Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping.

GJA5 GJB2

2.42e-04204021370487
Pubmed

Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit.

GJA5 ATP2A1

2.67e-042140228302382
Pubmed

Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin.

PIEZO2 CTSK

3.50e-042440232186512
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

DPY19L4 ATP6V0A1 TENM3 PIGK TMEM161B EBP LEMD2

3.95e-04120140735696571
Pubmed

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo.

FPR1 FPR2

5.13e-042940223708969
Pubmed

Genome-wide association study of smoking behaviours among Bangladeshi adults.

TENM3 VPS13B

7.07e-043440224665060
InteractionMFSD6 interactions

GJB2 SMIM1 SLC18A1 EBP

9.14e-0742364int:MFSD6
InteractionHTR3A interactions

DPY19L4 ATP6V0A1 SLC41A3 EBP LEMD2

1.33e-06108365int:HTR3A
InteractionPIEZO1 interactions

GJB2 ATP2A1 TSPAN5 FPR2

1.45e-0647364int:PIEZO1
InteractionGJB2 interactions

GJA5 GJB2 SLC18A1 EBP

6.44e-0668364int:GJB2
InteractionTSPAN15 interactions

DPY19L4 ZDHHC17 PIGK TSPAN5 EBP LEMD2

8.62e-06276366int:TSPAN15
InteractionHACD2 interactions

ATP2A1 SMIM1 SLC18A1 FPR2

1.36e-0582364int:HACD2
InteractionTMEM161B interactions

FPR1 TMEM161B FPR2

1.66e-0528363int:TMEM161B
InteractionFCER1G interactions

GJA5 SMIM1 SLC18A1 EBP

2.14e-0592364int:FCER1G
InteractionGPR89A interactions

ATP2A1 TSPAN5 FPR1 FPR2

6.08e-05120364int:GPR89A
InteractionSMIM1 interactions

SMIM1 SLC18A1 EBP

1.59e-0459363int:SMIM1
InteractionTTYH1 interactions

DPY19L4 ATP6V0A1 TMEM161B EBP LEMD2

1.83e-04300365int:TTYH1
InteractionTSPO2 interactions

SLC41A3 SLC18A1 EBP

1.93e-0463363int:TSPO2
InteractionSMCO4 interactions

SLC41A3 SLC18A1 EBP

2.02e-0464363int:SMCO4
InteractionMS4A13 interactions

GJA5 SLC18A1 EBP

2.02e-0464363int:MS4A13
InteractionORMDL1 interactions

SLC18A1 FPR1 EBP

2.32e-0467363int:ORMDL1
InteractionAGPAT2 interactions

ATP6V0A1 SLC23A2 FPR2

2.32e-0467363int:AGPAT2
InteractionNOMO1 interactions

ATP2A1 SLC18A1 FPR1 FPR2

2.96e-04181364int:NOMO1
InteractionBSCL2 interactions

IL20RB ZDHHC17 TSPAN5 EBP

3.28e-04186364int:BSCL2
InteractionRFT1 interactions

ATP2A1 TSPAN5 FPR2

3.91e-0480363int:RFT1
InteractionAGPAT3 interactions

ATP2A1 SLC18A1 TSPAN5

5.18e-0488363int:AGPAT3
InteractionLPAR1 interactions

ZDHHC17 ATP2A1 PIGK TMEM161B

5.20e-04210364int:LPAR1
InteractionARLN interactions

GJA5 SLC41A3 EBP

5.71e-0491363int:ARLN
InteractionCLIC2 interactions

CLIC4 CLIC2

5.78e-0420362int:CLIC2
InteractionTMEM60 interactions

SLC18A1 SLC23A2 EBP

5.89e-0492363int:TMEM60
InteractionLEMD2 interactions

ATP2A1 TSPAN5 LEMD2

6.28e-0494363int:LEMD2
InteractionZACN interactions

DPY19L4 GJB2 SLC41A3

6.67e-0496363int:ZACN
InteractionTLCD1 interactions

ATP2A1 EBP

7.01e-0422362int:TLCD1
InteractionGJB6 interactions

GJB2 EBP

7.01e-0422362int:GJB6
InteractionAGER interactions

FPR1 FPR2

7.01e-0422362int:AGER
InteractionCLIC5 interactions

CLIC4 CLIC2

7.01e-0422362int:CLIC5
InteractionRPRM interactions

DPY19L4 GJA5 SLC18A1

7.09e-0498363int:RPRM
InteractionVKORC1L1 interactions

ATP2A1 TSPAN5 FPR2

7.30e-0499363int:VKORC1L1
GeneFamilyFormyl peptide receptors

FPR1 FPR2

7.45e-063292198
GeneFamilyChloride intracellular channels

CLIC4 CLIC2

3.71e-056292307
GeneFamilyGap junction proteins

GJA5 GJB2

5.63e-0422292314
GeneFamilySolute carriers

SLC41A3 SLC18A1 SLC23A2 SLC2A11

3.46e-03395294752
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLIC4 ABCD2 CTSK FPR1 FPR2

7.24e-07189405b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLIC4 ABCD2 CTSK FPR1 FPR2

7.44e-07190405da58227565ad6a690828dd8554dd3670222f8582
ToppCellmLN-Macrophage|mLN / Region, Cell class and subclass

TMIGD3 CLIC2 CD300E FPR1 FPR2

9.57e-0720040568d709afd226241e002dae6d6820bccd1cfd87a1
ToppCellmLN-(6)_Macrophage|mLN / shred on region, Cell_type, and subtype

TMIGD3 CLIC2 CD300E FPR1 FPR2

9.57e-072004056dcba82a7d322102bae205543086e84c7655b3e0
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCD2 CD300E FPR1 FPR2

8.41e-06144404c0c5f254a960ba5e5f1354599d54e77360e6c2ac
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCD2 CD300E FPR1 FPR2

8.41e-061444041efa434e577d1f87e02df01667782f414d63bd60
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCD2 CTSK FPR1 FPR2

1.69e-05172404584af6537685cb459bf0fc298e6f46872016c116
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC|lymph-node_spleen / Manually curated celltypes from each tissue

GJB2 PIEZO2 TENM3 CLIC2

1.69e-051724041b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCellILEUM-non-inflamed-(3)_Inf._Macrophages|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GJB2 CD300E FPR1 FPR2

1.73e-05173404a8db746992a915a8431ac5c155612e89c4af3cad
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_activate-7|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLIC4 CTNS SSTR2 SLC2A11

1.85e-05176404dde46f06f6fc3f7ba83be91a0ee6231790955e3e
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCD2 CTSK FPR1 FPR2

1.85e-05176404b0b87eebcf5c994386b39ca607e17f10e9d9de74
ToppCellMonocytes-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

TMIGD3 CD300E FPR1 FPR2

1.85e-051764045b5f8655b0c6c56f98f70bce13e71f017d4b75a5
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCD2 CTSK FPR1 FPR2

1.89e-0517740471919b5c9bfa87fdd2cd44dfa057b66ea081be5d
ToppCell3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Erythrocytic-Meg|bone_marrow / Manually curated celltypes from each tissue

GJA5 PIEZO2 ITGA2B SMIM1

2.02e-0518040444ba37bead1ac39bce4d3eef00961063c50ced0d
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 ZDHHC17 TENM3 TSPAN5

2.11e-0518240453c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

CTSK CD300E FPR1 FPR2

2.16e-0518340406e4b05d86a7d643569e19575c2c9aa351d33f29
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AP5M1 CD300E FPR1 FPR2

2.16e-051834046e5b39c0170d62eb7fdd411dcfff51ed176573d0
ToppCellnormal_Lymph_Node-Myeloid_cells-Monocytes|normal_Lymph_Node / Location, Cell class and cell subclass

SLC18A1 CD300E FPR1 FPR2

2.21e-051844043cec28ff076fa53d034428de2bb1a237e0c1568c
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCD2 CTSK FPR1 FPR2

2.21e-051844048e5fc2bdd3071e782aa8c56b8a39f8ea8f03f623
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP6V0A1 ABCD2 CTSK FPR2

2.21e-05184404fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ITGA2B SMIM1 CLIC2 TSPAN5

2.25e-051854049f1a790680caaf9c1ec35db5e4b7641497401179
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCD2 CTSK FPR1 FPR2

2.25e-05185404afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Monocytes|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMIGD3 CD300E FPR1 FPR2

2.25e-05185404f8de11dd53b34d36368a2082f24ec1416cb7dbae
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCD2 CTSK FPR1 FPR2

2.25e-05185404775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP6V0A1 ABCD2 CTSK FPR2

2.30e-051864047950e03ea080238c168b9d807e217f459acdfb28
ToppCellIIF-Other|IIF / Disease, Lineage and Cell Type

ITGA2B SMIM1 CLIC2 TSPAN5

2.35e-05187404ae44d9261698cc0289750a546baf050f78b119b3
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCD2 CTSK FPR1 FPR2

2.45e-05189404287e59104687fe1665232c52993889f0f2c97f17
ToppCelldroplet-Lung-LUNG-1m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCD2 CTSK FPR1 FPR2

2.45e-051894046d24414ac6bd4f03f7a5ad3a6eba51d549a7b112
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLIC4 CD300E FPR1 FPR2

2.50e-05190404e1c02fe6fa43a36381cb9f02569fa9b1c5f5efdc
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLIC4 CD300E FPR1 FPR2

2.50e-051904046de15ec88426fbf52acb0a8371f82cf03b6a6237
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

ATP6V0A1 ABCD2 CTSK FPR2

2.55e-051914047bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLIC4 CD300E FPR1 FPR2

2.55e-0519140481f77bf497b8e0ae0affe7d5f4f00446547229f6
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GJB2 CD300E FPR1 FPR2

2.60e-05192404d44f46352bac414b45cc749f7cbdc3a159bd7ae8
ToppCell390C-Myeloid-Monocyte-CD14+_Monocyte|390C / Donor, Lineage, Cell class and subclass (all cells)

GJB2 CD300E FPR1 FPR2

2.66e-05193404a50ee6110ea272d9d9f41d48bb5d43711cc00a32
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GJB2 CD300E FPR1 FPR2

2.66e-05193404b044fca95f519ff2ceb378afe40a95911931a29e
ToppCell356C-Myeloid-Monocyte-CD14+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

GJB2 CD300E FPR1 FPR2

2.71e-051944043f9ac1de8605a7930f49a7ce0e32aea9997d7791
ToppCell356C-Myeloid-Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

GJB2 CD300E FPR1 FPR2

2.71e-05194404a41cde3088b43670210daab4f43a24aa83dbd45b
ToppCell3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Monocytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMIGD3 CD300E FPR1 FPR2

2.77e-05195404aa3914e277918299dc7d2995c0c72288462ad43d
ToppCell3'-Adult-LargeIntestine-Hematopoietic-Myeloid|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMIGD3 CD300E FPR1 FPR2

2.82e-0519640423e22dfb9f9aec17b83574295f889e75f46ded50
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid-mid_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ZDHHC17 SMIM1 CLIC2 TSPAN5

2.88e-05197404d8f99a9f2367c8bc9308b0c64d0226875262927a
ToppCell(7)_MNP|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CLIC2 CD300E FPR1 FPR2

2.88e-051974046790346736946984cc80d67668523ba70ab0b380
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

PIEZO2 TENM3 TSPAN5 VPS13B

2.88e-05197404f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TMIGD3 CTSK CLIC2 FPR1

3.00e-0519940480ed217d28ba1c07facd0e103c25a02658dd848d
ToppCellVE-granulo2|VE / Condition, Cell_class and T cell subcluster

CLIC4 CD300E FPR1 FPR2

3.00e-0519940405b47fdc01eccee0eaf4c781eeff93c47fe0533e
ToppCellVE-granulo2-|VE / Condition, Cell_class and T cell subcluster

CLIC4 CD300E FPR1 FPR2

3.00e-05199404455e92047201ddd0c29a437a838e5fa135de7995
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMIGD3 CD300E FPR1 FPR2

3.00e-05199404d2783e69da653184e38dc6d85b23521790fa24b8
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMIGD3 CD300E FPR1 FPR2

3.00e-05199404d3f77acb36ac7c56a47ca98b695f46ae5b9ecd12
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Cbln2_(Neuron.Slc17a6.Rora.Cbln2)|Thalamus / BrainAtlas - Mouse McCarroll V32

ABCA12 WFDC9 CD300E

3.00e-05674035202166895fd109ad0d7584fc35c74814a59ce2b
ToppCellInfluenza-Influenza_Severe-Others|Influenza_Severe / Disease, condition lineage and cell class

ITGA2B SMIM1 CLIC2 TSPAN5

3.05e-052004048909da4f7da3bc469a2becb4cfa5c25012af5845
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMIGD3 CD300E FPR1 FPR2

3.05e-0520040426df6ac63710655604888c3be6509b6c4befc0be
ToppCellmLN-(6)_Macrophage-(61)_LYVE1_Macrophage|mLN / shred on region, Cell_type, and subtype

CLIC2 CD300E FPR1 FPR2

3.05e-05200404a20f5ec61d492d8a2adf695ec304b5d57296aa8f
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TMIGD3 CTNS CD300E FPR2

3.05e-05200404f11ae9055e72c938b6c9e52701478b2eee681ac4
ToppCellmLN-Macrophage-LYVE1_Macrophage|mLN / Region, Cell class and subclass

CLIC2 CD300E FPR1 FPR2

3.05e-0520040489cf739a3c2f5d30e547404f2f2ec6500cd1d65d
ToppCellBiopsy_IPF-Mesenchymal-HAS1_High_Fibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

GJB2 PIEZO2 TENM3 CTSK

3.05e-05200404d02e256b5d65a5c982ba5696bc7e077281ca3e24
ToppCellMS-IIF-Others|IIF / Disease, condition lineage and cell class

ITGA2B SMIM1 CLIC2 TSPAN5

3.05e-05200404e585ac220594f860f2fa7036bb23b165e2d74a41
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMIGD3 CD300E FPR1 FPR2

3.05e-0520040407819a90ac347883b78d0bb3cd8c5eb0d66e1e22
ToppCellmetastatic_Lymph_Node-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

CLIC4 GJB2 CTSK

3.88e-0573403116259a036373bccaeb77fe3c675741a5ca81c52
ToppCellASK454-Immune-Macrophages|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

CD300E FPR1 FPR2

4.20e-0575403572cea9d3f9afa218037550dacc3524534c673ce
ToppCellASK454-Immune-Macrophages|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

CD300E FPR1 FPR2

4.37e-0576403f4fdc5cb2a561e58ea020dac48ee8647577f9713
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Cacng4_(Non-anterior_nuclei)|Thalamus / BrainAtlas - Mouse McCarroll V32

ATP2A1 CD300E FPR2

4.37e-05764034afc8d0e79870c635a89dd8e7ca91ebfe482b4ab
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TMIGD3 IL20RB GJA5

6.11e-0585403d95b1c90dce5a13db001e242b9969b553fd005e6
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TMIGD3 IL20RB GJA5

6.11e-05854030f0425f73373134bd34e185dff4c4e294e12e492
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TMIGD3 IL20RB GJA5

6.11e-058540336a1d02fff9a2388619bc5651aa62f05e9142af7
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)|Striatum / BrainAtlas - Mouse McCarroll V32

IL20RB GJA5 CD300E

9.62e-05994030d5684978f34258d4eb4941eb6c60393a9bc84ed
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)--|Striatum / BrainAtlas - Mouse McCarroll V32

IL20RB GJA5 CD300E

9.62e-05994031244f50bb66eea555a284ff5c35ac755d1e9080d
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)-|Striatum / BrainAtlas - Mouse McCarroll V32

IL20RB GJA5 CD300E

9.62e-05994030c27df8ecc1956b056930da9ab1c96df7fb9f7b5
ToppCellTCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type-2|TCGA-Adrenal / Sample_Type by Project: Shred V9

IL20RB GJB2 FPR2

1.74e-04121403a74f530abc7295bed3e73b37ef47fcb04b0dcc6e
ToppCell|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CTNS ABCD2 SMIM1

1.74e-04121403da8fe561dcf50792d0cbcaad383d564f900a6677
ToppCellMyeloid-C_(Cd16+_Monocyte)|World / shred on cell class and cell subclass (v4)

CD300E FPR1 FPR2

1.92e-04125403c73a77340e79f73fd1f900724e82a94d82e6b1bf
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TMIGD3 SMIM1 CD300E

2.51e-041374035cb84392e4483f50e09fb7395e2ec98f3eb6ecf3
ToppCellfacs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD300E FPR1 FPR2

2.62e-0413940396e6fed23e7a69f678f85e8e2fe77a7491586b4b
ToppCellCOVID-19_Mild-Neu_0|World / 5 Neutrophil clusters in COVID-19 patients

ABCD2 TENM3 SLC18A1

2.68e-0414040393f024473b1bb3bf93ae776fd6a8fc5e93d013f0
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Erythrocyte|Erythro-cells / Lineage, cell class and subclass

SMIM1 CLIC2 TSPAN5

2.91e-041444037fbedc65314cfb06bcc527d794b5de7858f7c5ec
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC18A1 FPR1 FPR2

2.97e-04145403ab0e254a8d01021619853a6c175f620ccef217d8
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC18A1 FPR1 FPR2

2.97e-041454032beb4ea3838796c580076ab7769de877a3a0552c
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA2B SLC41A3 FPR1

3.21e-04149403c9334f319a0c943268e54b6f0c9446736172c3a9
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_Inf._Macrophages|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GJB2 FPR1 FPR2

3.34e-0415140388f7498f29e43441e0982f9f97ea563edf2835a4
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJB2 FPR1 FPR2

3.47e-041534030ef7c45cdd854c79e527006034029767f8e108b2
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300E FPR1 FPR2

3.68e-041564036e60e860603a7e8194f437a574ff8e887f6083b8
ToppCellfacs-Spleen-nan-24m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCD2 FPR1 FPR2

3.68e-04156403034d4359359a44c205c6931f38a375271ac2752b
ToppCellfacs-Spleen-nan-24m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCD2 FPR1 FPR2

3.68e-041564032a4dac4100c0339aad4905b8eaca6e8fe806718b
ToppCellfacs-Spleen-nan-24m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCD2 FPR1 FPR2

3.68e-0415640321267718d3a3dc19988663b6846aed8bb3eae836
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l8|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC18A1 FPR1 FPR2

3.75e-041574035098675f64342c41c5ca3551b24962d10c83e64d
ToppCellPND07-28-samps|World / Age Group, Lineage, Cell class and subclass

CTSK FPR1 FPR2

3.75e-04157403a2005768a6d268879e3fd6dbd8cf674dc98be587
ToppCelldroplet-Spleen-nan-24m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300E FPR1 FPR2

3.82e-0415840372e4f8ae137a7dddee0dc6236532e0711065e6af
ToppCelldroplet-Spleen-nan-24m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300E FPR1 FPR2

3.82e-04158403e1a8dba5a88bc3ce112829c5ecb112cbbee5b078
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL20RB ITGA2B ABCD2

3.89e-04159403709b57f992a29878cc899d760d144d36cb5cb280
ToppCellfacs-Lung-Endomucin-24m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300E FPR1 FPR2

3.89e-04159403886cbaef39a3517514a3896b6b960d01a3af043d
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJB2 CD300E FPR2

3.96e-041604032020b6defbaf5b5db12af37f0103ac028a8ca76e
ToppCelldroplet-Limb_Muscle-nan-24m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300E FPR1 FPR2

3.96e-04160403984990be02642a562f0c60ea99c01f005e7c02c2
ToppCellfacs-MAT-Fat-18m-Myeloid-myeloid_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300E FPR1 FPR2

3.96e-04160403bd5fa7959bfe81011b8d798535b73ea1eee008b3
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJB2 CD300E FPR2

3.96e-04160403af7cf0dc5fe7c02f7d6c436f6dde766c79ff0eae
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GJB2 FPR1 FPR2

3.96e-0416040308696d93ff42a1beca23c70ab3e0d082cfff4aa7
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300E FPR1 FPR2

3.96e-041604031f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCellPND01-03-samps-Myeloid-Macrophage-macrophage-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CTSK FPR1 FPR2

4.03e-041614035925ee646aa040550e3f8a164a13c8a5c0353319
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

PIEZO2 ITGA2B TSPAN5

4.18e-04163403961c3a1303108afd680365466045f3460a30a7b0
ToppCellnormal_Lymph_Node-Myeloid_cells-Monocytes|Myeloid_cells / Location, Cell class and cell subclass

CD300E FPR1 FPR2

4.18e-041634037d7f18e5c99be125e95bc180823430291b770d05
ToppCellfacs-Lung-Endomucin-24m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300E FPR1 FPR2

4.18e-0416340304152557aae230e9587fcc16cbabf1247cc5b419
ToppCellfacs-Lung-Endomucin-24m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300E FPR1 FPR2

4.18e-041634030644eb8a66d4e944063125c423de66d2393388b1
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300E FPR1 FPR2

4.25e-0416440315d52666e5150e7c34b1f641a937fb2d5e8aaf8a
ComputationalPorins / transporters.

GJA5 GJB2 ITGA2B CLIC2 FPR1

3.39e-05211205MODULE_63
Drug1-phenylpyrazole

CLIC4 CLIC2 AP3D1

1.26e-0528373CID000070769
Drugt-boc-MLP

FPR1 FPR2

1.54e-054372CID000125627
Drugcyclooctylamine

FPR1 FPR2

2.56e-055372CID000002903
Drugbacteriochlorin A

FPR1 FPR2

3.84e-056372CID000159279
DrugL-phosphatidyl-glycerol

FPR1 FPR2

3.84e-056372CID000454706
Drugdimethylfumarate

FPR1 FPR2

3.84e-056372CID000010262
Drugoxovanadium

GJA5 ATP6V0A1 CTNS ATP2A1

4.24e-05120374CID000024411
DrugL-valine methyl ester hydrochloride

FPR1 FPR2

7.15e-058372CID000094285
DrugFmlp Ome

FPR1 FPR2

7.15e-058372CID000122066
DrugAC1L524D

FPR1 FPR2

7.15e-058372CID000196667
DiseasePancreatic Ductal Adenocarcinoma

ABCD2 ABCA12

9.29e-0511392C1335302
Diseasesialic acid-binding Ig-like lectin 14 measurement

FPR1 FPR2

1.11e-0412392EFO_0008284
Diseaseairway imaging measurement

GJA5 ABCA12

1.16e-0338392EFO_0007627

Protein segments in the cluster

PeptideGeneStartEntry
MWGLKVLLLPVVSFA

CTSK

1

P43235
PFSQRLFMILWLKGV

CLIC4

36

Q9Y696
KLIKWLMIAIPATFV

ABCD2

146

Q9UBJ2
VIWAFLKPMLLGRIL

ABCA12

796

Q86UK0
KLPLLLSMLGAVFWV

CD300E

181

Q496F6
GKIWLTVLFIFRIMI

GJB2

21

P29033
QWLMVLKISLPVIGL

ATP2A1

966

O14983
WVLIKIIKLFGALTP

AP3D1

236

O14617
LLLVFLGILWVKMGK

LEMD2

221

Q8NC56
LAMKVIVGPWILALV

FPR2

141

P25090
MQFVLSWVFLVGILK

IGHV3-38

1

A0A0C4DH36
LLIWIIGQKFPKSME

AP5M1

386

Q9H0R1
ILGLWALIIMVFFKT

PIGK

371

Q92643
VGFMLILVVVPLFVW

IL20RB

241

Q6UXL0
ILVVVPLFVWKMGRL

IL20RB

246

Q6UXL0
MKPLLVVFVFLFLWD

DEFB134

1

Q4QY38
WIMLILVGLGFPFIM

SLC2A11

416

Q9BYW1
VGKVWLTVLFIFRML

GJA5

21

P36382
IIGLSLWKEFFPRLM

DPY19L4

536

Q7Z388
MIRNWLTIFILFPLK

CTNS

1

O60931
FMNALWLVLPGVLVL

EBP

191

Q15125
PFCQRLFMILWLKGV

CLIC2

31

O15247
WVIFIMGGLILVIPF

OR1E2

206

P47887
FVVIFIPWEMRIKKI

TMC3

116

Q7Z5M5
APLFMVLLWVKPITK

TMEM161B

276

Q8NDZ6
LAKKVIIGPWVMALL

FPR1

141

P21462
ILKFGWFPIILAMVI

SLC41A3

281

Q96GZ6
MKPWILLLVMFISGV

WFDC9

1

Q8NEX5
MKVLGGVALFWIIFI

SMIM1

51

B2RUZ4
LTILVLAMWKVGFFK

ITGA2B

1011

P08514
VWGVSLLVILPIMIY

SSTR2

166

P30874
FKMFPIILAILVSWL

SLC23A2

311

Q9UGH3
GMIIVLLICIVWFPL

PIEZO2

2406

Q9H5I5
LMVAVVGRLFQKWFP

TENM3

1036

Q9P273
FRQKVMLGTPFLVIW

ZDHHC17

301

Q8IUH5
MLGTPFLVIWLVGFI

ZDHHC17

306

Q8IUH5
VVALLCVPWMLLFKP

ATP6V0A1

641

Q93050
PVWLFLVVGGVMFIL

TSPAN5

61

P62079
MQWVLPKITIKLFAP

VPS13B

1326

Q7Z7G8
LKVCFLPVMWLFILL

TMIGD3

51

P0DMS9
LWKGMLLFIISVVLV

TMEM249

61

Q2WGJ8
IVKAIGFPWLMVITG

SLC18A1

451

P54219