Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionneurohypophyseal hormone activity

OXT AVP

3.34e-062372GO:0005185
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

EPHB4 ERBB2 ERBB3 TIE1

6.23e-0665374GO:0004714
GeneOntologyMolecularFunctionV1A vasopressin receptor binding

OXT AVP

1.00e-053372GO:0031894
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

EPHB4 ERBB2 ERBB3 TIE1

1.81e-0585374GO:0019199
GeneOntologyMolecularFunctionvasopressin receptor binding

OXT AVP

2.00e-054372GO:0031893
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMA5 CRELD1 LAMC2 SSPOP TNC

2.39e-05188375GO:0005201
GeneOntologyMolecularFunctionErbB-3 class receptor binding

ERBB2 ERBB3

4.99e-056372GO:0043125
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

EPHB4 ERBB2 ERBB3 TIE1

1.46e-04145374GO:0004713
GeneOntologyMolecularFunctioncomplement component C1q complex binding

C1QBP MEGF10

1.49e-0410372GO:0001849
GeneOntologyMolecularFunctionintegrin binding

LAMA5 TNC SVEP1 EGFL6

3.00e-04175374GO:0005178
GeneOntologyMolecularFunctionWnt receptor activity

FZD8 PKD1

4.46e-0417372GO:0042813
GeneOntologyMolecularFunctionopsonin binding

C1QBP MEGF10

9.76e-0425372GO:0001846
GeneOntologyMolecularFunctionscavenger receptor activity

MEGF10 STAB1

1.14e-0327372GO:0005044
GeneOntologyMolecularFunctionhyaluronic acid binding

C1QBP STAB1

1.31e-0329372GO:0005540
GeneOntologyMolecularFunctioncomplement binding

C1QBP MEGF10

1.60e-0332372GO:0001848
GeneOntologyMolecularFunctionneuropeptide hormone activity

OXT AVP

1.81e-0334372GO:0005184
GeneOntologyMolecularFunctionneuropeptide activity

OXT AVP

1.81e-0334372GO:0160041
GeneOntologyMolecularFunctionWnt-protein binding

FZD8 WIF1

1.81e-0334372GO:0017147
GeneOntologyMolecularFunctionprotein kinase activity

EPHB4 ERBB2 ERBB3 TIE1 AVP

4.74e-03600375GO:0004672
GeneOntologyBiologicalProcessbranching involved in lymph vessel morphogenesis

TIE1 PKD1

8.38e-063352GO:0060854
GeneOntologyBiologicalProcessgrooming behavior

KCNQ2 OXT AVP

8.84e-0624353GO:0007625
GeneOntologyBiologicalProcesslymph vessel morphogenesis

TIE1 SVEP1 PKD1

8.84e-0624353GO:0036303
GeneOntologyBiologicalProcesscirculatory system development

EPHB4 FZD8 CRELD1 ERBB2 ERBB3 OXT TIE1 SVEP1 WIF1 STAB1 PKD1

1.63e-0514423511GO:0072359
GeneOntologyBiologicalProcessmaternal aggressive behavior

OXT AVP

1.67e-054352GO:0002125
GeneOntologyBiologicalProcessregulation of cell adhesion

EPHB4 C1QBP LAMA5 ERBB2 ERBB3 TNC MEGF10 EGFL6 PKD1

1.77e-05927359GO:0030155
GeneOntologyBiologicalProcesslymph vessel development

TIE1 SVEP1 PKD1

2.15e-0532353GO:0001945
GeneOntologyBiologicalProcessheart development

EPHB4 CRELD1 ERBB2 ERBB3 OXT TIE1 WIF1 PKD1

3.10e-05757358GO:0007507
GeneOntologyBiologicalProcessregulation of female receptivity

OXT AVP

1.00e-049352GO:0045924
GeneOntologyBiologicalProcessvasculature development

EPHB4 FZD8 ERBB2 TIE1 SVEP1 WIF1 STAB1 PKD1

1.75e-04969358GO:0001944
GeneOntologyBiologicalProcessfemale mating behavior

OXT AVP

1.83e-0412352GO:0060180
GeneOntologyBiologicalProcessaggressive behavior

OXT AVP

2.16e-0413352GO:0002118
GeneOntologyBiologicalProcessERBB2-ERBB3 signaling pathway

ERBB2 ERBB3

2.16e-0413352GO:0038133
GeneOntologyBiologicalProcessERBB3 signaling pathway

ERBB2 ERBB3

2.51e-0414352GO:0038129
GeneOntologyBiologicalProcesssocial behavior

KCNQ2 OXT AVP

2.67e-0474353GO:0035176
GeneOntologyBiologicalProcessbiological process involved in intraspecies interaction between organisms

KCNQ2 OXT AVP

2.89e-0476353GO:0051703
GeneOntologyBiologicalProcessbranching morphogenesis of an epithelial tube

LAMA5 TIE1 TNC PKD1

3.42e-04198354GO:0048754
GeneOntologyBiologicalProcessmaternal behavior

OXT AVP

4.21e-0418352GO:0042711
GeneOntologyBiologicalProcesstube morphogenesis

EPHB4 FZD8 LAMA5 ERBB2 TIE1 TNC STAB1 PKD1

4.80e-041125358GO:0035239
GeneOntologyBiologicalProcesspositive regulation of kinase activity

EPHB4 FZD8 ERBB2 ERBB3 TIE1

5.69e-04405355GO:0033674
GeneOntologyBiologicalProcesslymphangiogenesis

TIE1 PKD1

5.76e-0421352GO:0001946
GeneOntologyBiologicalProcessparental behavior

OXT AVP

5.76e-0421352GO:0060746
GeneOntologyBiologicalProcesscell-substrate adhesion

C1QBP LAMA5 SVEP1 EGFL6 PKD1

6.01e-04410355GO:0031589
GeneOntologyBiologicalProcessmorphogenesis of a branching epithelium

LAMA5 TIE1 TNC PKD1

6.62e-04236354GO:0061138
GeneOntologyBiologicalProcessblood vessel development

EPHB4 FZD8 ERBB2 TIE1 WIF1 STAB1 PKD1

8.17e-04929357GO:0001568
GeneOntologyBiologicalProcesstransmission of nerve impulse

KCNQ2 CLCN1 AVP

8.99e-04112353GO:0019226
GeneOntologyBiologicalProcessmorphogenesis of a branching structure

LAMA5 TIE1 TNC PKD1

9.23e-04258354GO:0001763
GeneOntologyBiologicalProcessERBB2 signaling pathway

ERBB2 ERBB3

9.56e-0427352GO:0038128
GeneOntologyBiologicalProcessregulation of complement activation

C1QBP SVEP1

9.56e-0427352GO:0030449
GeneOntologyCellularComponentERBB3:ERBB2 complex

ERBB2 ERBB3

3.05e-062372GO:0038143
GeneOntologyCellularComponentextracellular matrix

LAMA5 CRELD1 LAMC2 FCGBP SSPOP TNC SVEP1 EGFL6

1.55e-05656378GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMA5 CRELD1 LAMC2 FCGBP SSPOP TNC SVEP1 EGFL6

1.59e-05658378GO:0030312
GeneOntologyCellularComponentlaminin-5 complex

LAMA5 LAMC2

1.82e-054372GO:0005610
GeneOntologyCellularComponentbasement membrane

LAMA5 LAMC2 TNC EGFL6

6.28e-05122374GO:0005604
GeneOntologyCellularComponentlaminin complex

LAMA5 LAMC2

1.36e-0410372GO:0043256
GeneOntologyCellularComponentsynapse-associated extracellular matrix

LAMA5 TNC

2.35e-0413372GO:0099535
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMA5 CRELD1 LAMC2 SSPOP TNC EGFL6

3.08e-04530376GO:0062023
GeneOntologyCellularComponentmembrane protein complex

FZD8 KCNQ2 ERBB2 ERBB3 ANKFY1 CLCN1 SSPOP SOCS7 PKD1

9.65e-041498379GO:0098796
GeneOntologyCellularComponentneuronal dense core vesicle

FZD8 AVP

1.85e-0336372GO:0098992
GeneOntologyCellularComponentdense core granule

FZD8 AVP

4.42e-0356372GO:0031045
MousePhenodecreased atrioventricular cushion size

CRELD1 ERBB2 ERBB3

6.41e-0618293MP:0000301
MousePhenoabnormal Schwann cell precursor morphology

ERBB2 ERBB3

1.25e-053292MP:0004074
MousePhenodecreased Schwann cell precursor number

ERBB2 ERBB3

1.25e-053292MP:0004075
MousePhenoabnormal atrioventricular cushion morphology

CRELD1 ERBB2 ERBB3 PKD1

1.73e-0576294MP:0000297
MousePhenomegacephaly

LAMA5 KCNQ2 SOCS7

1.79e-0525293MP:0000434
MousePhenoabnormal fetal atrioventricular canal morphology

CRELD1 ERBB2 ERBB3 PKD1

2.23e-0581294MP:0006107
MousePhenolethality during fetal growth through weaning, complete penetrance

LAMA5 KCNQ2 LAMC2 ERBB2 ERBB3 ECEL1 TIE1 AVP SOCS7 PKD1

1.47e-0412692910MP:0011111
MousePhenoskin edema

TIE1 SVEP1 PKD1

1.75e-0453293MP:0001786
MousePhenoabnormal myocardial trabeculae morphology

EPHB4 ERBB2 ERBB3 PKD1

2.10e-04144294MP:0002189
MousePhenoabnormal phrenic nerve innervation pattern to diaphragm

ERBB2 ECEL1

2.26e-0411292MP:0012055
MousePhenoabnormal phrenic nerve innervation pattern

ERBB2 ECEL1

2.26e-0411292MP:0012054
MousePhenoabnormal epidermal-dermal junction morphology

LAMA5 LAMC2

2.71e-0412292MP:0011159
MousePhenorespiratory failure

ERBB2 ERBB3 ECEL1 TIE1

3.53e-04165294MP:0001953
MousePhenoabnormal petrosal ganglion morphology

ERBB2 ERBB3

3.72e-0414292MP:0001084
MousePhenodecreased respiration

ERBB2 ERBB3 ECEL1 TIE1

3.95e-04170294MP:0014274
MousePhenoabnormal lymphangiogenesis

TIE1 SVEP1

4.29e-0415292MP:0008778
MousePhenopoor circulation

ERBB2 ERBB3

6.95e-0419292MP:0001633
MousePhenoabnormal ventral spinal root morphology

ERBB2 ERBB3

6.95e-0419292MP:0003993
DomainGrowth_fac_rcpt_

EPHB4 LAMA5 CRELD1 LAMC2 ERBB2 ERBB3 TIE1 TNC SVEP1 EGFL6 STAB1

6.85e-151563711IPR009030
DomainEGF_2

EPHB4 LAMA5 CRELD1 LAMC2 TIE1 SSPOP TNC SVEP1 MEGF10 EGFL6 WIF1 STAB1

7.02e-142653712PS01186
DomainEGF

LAMA5 CRELD1 LAMC2 FCGBP TIE1 TNC SVEP1 MEGF10 EGFL6 WIF1 STAB1

6.35e-132353711SM00181
DomainEGF-like_dom

LAMA5 CRELD1 LAMC2 FCGBP TIE1 TNC SVEP1 MEGF10 EGFL6 WIF1 STAB1

1.19e-122493711IPR000742
DomainEGF_1

LAMA5 CRELD1 LAMC2 TIE1 SSPOP TNC SVEP1 MEGF10 EGFL6 WIF1 STAB1

1.55e-122553711PS00022
DomainEGF-like_CS

EPHB4 LAMA5 CRELD1 LAMC2 TIE1 TNC SVEP1 MEGF10 EGFL6 WIF1 STAB1

1.99e-122613711IPR013032
DomainEGF_3

CRELD1 TIE1 SSPOP TNC SVEP1 MEGF10 EGFL6 WIF1 STAB1

6.21e-10235379PS50026
DomainEGF_extracell

TIE1 TNC SVEP1 MEGF10 WIF1 STAB1

1.83e-0960376IPR013111
DomainEGF_2

TIE1 TNC SVEP1 MEGF10 WIF1 STAB1

1.83e-0960376PF07974
DomainLaminin_EGF

LAMA5 CRELD1 LAMC2 MEGF10 STAB1

7.16e-0935375PF00053
DomainLaminin_EGF

LAMA5 CRELD1 LAMC2 MEGF10 STAB1

1.10e-0838375IPR002049
DomainEGF_Lam

LAMA5 LAMC2 MEGF10 STAB1

6.53e-0735374SM00180
Domain-

SVEP1 EGFL6 STAB1

1.17e-06113732.40.155.10
DomainGFP-like

SVEP1 EGFL6 STAB1

1.17e-0611373IPR023413
DomainNeurhyp_horm

OXT AVP

3.82e-062372PD001676
DomainNeurohypophysial_hormone_CS

OXT AVP

3.82e-062372IPR022423
DomainHormone_4

OXT AVP

3.82e-062372PF00220
DomainHormone_5

OXT AVP

3.82e-062372PF00184
Domain-

OXT AVP

3.82e-0623722.60.9.10
DomainNEUROHYPOPHYS_HORM

OXT AVP

3.82e-062372PS00264
DomainNH

OXT AVP

3.82e-062372SM00003
DomainEGF

TIE1 TNC SVEP1 WIF1 STAB1

4.73e-06126375PF00008
DomainFurin_repeat

CRELD1 ERBB2 ERBB3

5.72e-0618373IPR006212
DomainFU

CRELD1 ERBB2 ERBB3

5.72e-0618373SM00261
DomainhEGF

SVEP1 MEGF10 WIF1

2.27e-0528373PF12661
DomainNeurhyp_horm

OXT AVP

2.29e-054372IPR000981
DomainTyr_kinase_EGF/ERB/XmrK_rcpt

ERBB2 ERBB3

2.29e-054372IPR016245
DomainTyrKc

EPHB4 ERBB2 ERBB3 TIE1

2.70e-0588374SM00219
DomainTyr_kinase_cat_dom

EPHB4 ERBB2 ERBB3 TIE1

2.70e-0588374IPR020635
DomainEGF_LAM_2

LAMA5 LAMC2 STAB1

2.80e-0530373PS50027
DomainEGF_LAM_1

LAMA5 LAMC2 STAB1

2.80e-0530373PS01248
DomainPROTEIN_KINASE_TYR

EPHB4 ERBB2 ERBB3 TIE1

3.96e-0597374PS00109
DomainTyr_kinase_AS

EPHB4 ERBB2 ERBB3 TIE1

3.96e-0597374IPR008266
DomainGF_recep_IV

ERBB2 ERBB3

5.70e-056372PF14843
DomainGF_recep_IV

ERBB2 ERBB3

5.70e-056372IPR032778
DomainFurin-like

ERBB2 ERBB3

7.97e-057372PF00757
DomainRcpt_L-dom

ERBB2 ERBB3

7.97e-057372IPR000494
DomainFurin-like_Cys-rich_dom

ERBB2 ERBB3

7.97e-057372IPR006211
DomainRecep_L_domain

ERBB2 ERBB3

7.97e-057372PF01030
Domain-

ERBB2 ERBB3

7.97e-0573723.80.20.20
DomainEGF_CA

CRELD1 SVEP1 EGFL6 STAB1

9.69e-05122374SM00179
DomainEGF-like_Ca-bd_dom

CRELD1 SVEP1 EGFL6 STAB1

1.03e-04124374IPR001881
DomainLAMININ_IVA

LAMA5 LAMC2

1.06e-048372PS51115
DomainLaminin_B

LAMA5 LAMC2

1.06e-048372PF00052
DomainLamB

LAMA5 LAMC2

1.06e-048372SM00281
DomainLaminin_IV

LAMA5 LAMC2

1.06e-048372IPR000034
DomainPkinase_Tyr

EPHB4 ERBB2 ERBB3 TIE1

1.20e-04129374PF07714
DomainSer-Thr/Tyr_kinase_cat_dom

EPHB4 ERBB2 ERBB3 TIE1

1.56e-04138374IPR001245
DomainEphrin_rec_like

EPHB4 SVEP1

2.08e-0411372PF07699
DomainTIL

FCGBP SSPOP

2.49e-0412372PF01826
DomainC8

FCGBP SSPOP

2.49e-0412372PF08742
DomainUnchr_dom_Cys-rich

FCGBP SSPOP

2.94e-0413372IPR014853
DomainC8

FCGBP SSPOP

2.94e-0413372SM00832
DomainTIL_dom

FCGBP SSPOP

3.42e-0414372IPR002919
DomainVWD

FCGBP SSPOP

4.50e-0416372SM00216
DomainVWF_type-D

FCGBP SSPOP

4.50e-0416372IPR001846
DomainVWFD

FCGBP SSPOP

4.50e-0416372PS51233
DomainVWD

FCGBP SSPOP

4.50e-0416372PF00094
DomainEMI

SSPOP MEGF10

5.10e-0417372PS51041
DomainVWC_out

FCGBP SSPOP

6.39e-0419372SM00215
DomainEGF_CA

CRELD1 SVEP1 EGFL6

6.54e-0486373PF07645
DomainGalactose-bd-like

EPHB4 LAMA5 SSPOP

8.47e-0494373IPR008979
DomainEGF_Ca-bd_CS

CRELD1 SVEP1 EGFL6

9.28e-0497373IPR018097
DomainEGF_CA

CRELD1 SVEP1 EGFL6

9.85e-0499373PS01187
DomainASX_HYDROXYL

CRELD1 SVEP1 EGFL6

1.01e-03100373PS00010
DomainEphrin_rec_like

EPHB4 SVEP1

1.11e-0325372SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

EPHB4 SVEP1

1.11e-0325372IPR011641
DomainEGF-type_Asp/Asn_hydroxyl_site

CRELD1 SVEP1 EGFL6

1.20e-03106373IPR000152
DomainVWC

FCGBP SSPOP

2.57e-0338372SM00214
DomainVWF_dom

FCGBP SSPOP

3.13e-0342372IPR001007
DomainL_dom-like

FBXL17 ERBB2 ERBB3 PKD1

3.91e-03328374IPR032675
Domainfn3

EPHB4 TIE1 TNC

4.01e-03162373PF00041
DomainLDLRA_1

SSPOP PKD1

4.07e-0348372PS01209
DomainLDLRA_2

SSPOP PKD1

4.24e-0349372PS50068
DomainFN3

EPHB4 TIE1 TNC

5.80e-03185373SM00060
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

LAMA5 LAMC2 ERBB2 ERBB3

1.65e-0646274M239
PathwayREACTOME_GRB7_EVENTS_IN_ERBB2_SIGNALING

ERBB2 ERBB3

3.52e-055272M26937
PathwayREACTOME_VASOPRESSIN_LIKE_RECEPTORS

OXT AVP

5.27e-056272M27289
PathwayREACTOME_VASOPRESSIN_LIKE_RECEPTORS

OXT AVP

5.27e-056272MM14989
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMA5 LAMC2 TNC

1.90e-0459273M27218
PathwayPID_INTEGRIN4_PATHWAY

LAMA5 LAMC2

1.92e-0411272M158
PathwayREACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING

ERBB2 ERBB3

1.92e-0411272MM15478
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING

ERBB2 ERBB3

2.30e-0412272MM14550
PathwayWP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY

LAMA5 LAMC2 ERBB2

2.65e-0466273MM15925
PathwayPID_INTEGRIN1_PATHWAY

LAMA5 LAMC2 TNC

2.65e-0466273M18
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING

ERBB2 ERBB3

2.72e-0413272M549
PathwayREACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING

ERBB2 ERBB3

2.72e-0413272M27729
PathwayREACTOME_ERBB2_REGULATES_CELL_MOTILITY

ERBB2 ERBB3

2.72e-0413272MM15320
PathwayREACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING

ERBB2 ERBB3

3.17e-0414272MM14761
PathwayREACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING

ERBB2 ERBB3

3.17e-0414272MM14531
PathwayPID_ERBB_NETWORK_PATHWAY

ERBB2 ERBB3

3.65e-0415272M201
PathwayREACTOME_ERBB2_REGULATES_CELL_MOTILITY

ERBB2 ERBB3

3.65e-0415272M27608
PathwayWP_FOCAL_ADHESION

LAMA5 LAMC2 ERBB2 TNC

4.14e-04187274MM15913
PathwayREACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING

ERBB2 ERBB3

4.17e-0416272M570
PathwayWP_FOCAL_ADHESION

LAMA5 LAMC2 ERBB2 TNC

5.24e-04199274M39402
PathwayKEGG_FOCAL_ADHESION

LAMA5 LAMC2 ERBB2 TNC

5.24e-04199274M7253
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMA5 LAMC2 TNC

5.38e-0484273M7098
PathwayWP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY

FZD8 ERBB2 PKD1

5.57e-0485273M48315
PathwayREACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING

ERBB2 ERBB3

7.97e-0422272M26929
PathwayBIOCARTA_HER2_PATHWAY

ERBB2 ERBB3

8.72e-0423272MM1480
PathwayBIOCARTA_HER2_PATHWAY

ERBB2 ERBB3

8.72e-0423272M18719
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL

ERBB2 ERBB3

1.03e-0325272M47934
PathwayREACTOME_SIGNALING_BY_ERBB2_IN_CANCER

ERBB2 ERBB3

1.12e-0326272M29535
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_SIGNALING

ERBB2 ERBB3

1.12e-0326272MM15501
PathwayPID_WNT_SIGNALING_PATHWAY

FZD8 WIF1

1.29e-0328272M77
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_SIGNALING

ERBB2 ERBB3

1.39e-0329272M27756
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMA5 LAMC2

1.49e-0330272M27772
PathwayREACTOME_LAMININ_INTERACTIONS

LAMA5 LAMC2

1.49e-0330272M27216
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

LAMA5 LAMC2

1.49e-0330272M39641
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

LAMA5 LAMC2

1.49e-0330272MM15812
PathwayWP_MAMMARY_GLAND_DEVELOPMENT_PREGNANCY_AND_LACTATION_STAGE_3_OF_4

ERBB2 ERBB3

1.80e-0333272M39455
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA5 LAMC2

1.80e-0333272M39503
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMA5 LAMC2

2.77e-0341272M27778
PathwayPID_ERBB2_ERBB3_PATHWAY

ERBB2 ERBB3

3.18e-0344272M175
PathwayREACTOME_SIGNALING_BY_ERBB2

ERBB2 ERBB3

3.18e-0344272MM14520
PathwayKEGG_PATHWAYS_IN_CANCER

FZD8 LAMA5 LAMC2 ERBB2

3.20e-03325274M12868
PathwayPID_PS1_PATHWAY

SSPOP WIF1

3.47e-0346272M70
PathwayWP_ERBB_SIGNALING_PATHWAY

ERBB2 ERBB3

3.47e-0346272MM15950
PathwayPID_FANCONI_PATHWAY

FAAP100 SSPOP

3.62e-0347272M1
PathwayREACTOME_SIGNALING_BY_PTK6

ERBB2 ERBB3

3.77e-0348272MM15479
PathwayREACTOME_SIGNALING_BY_ERBB2

ERBB2 ERBB3

4.09e-0350272M553
PathwayREACTOME_SIGNALING_BY_PTK6

ERBB2 ERBB3

4.75e-0354272M29742
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

ERBB2 ERBB3

4.93e-0355272M47952
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPHB4 ZXDC LAMA5 KCNQ2 ERBB2 RAPGEF6 ZNF865 FAAP100 TMC6 PKD1

2.12e-071105381035748872
Pubmed

Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.

LAMA5 TIE1 SVEP1

6.67e-071638328179430
Pubmed

H1047R phosphatidylinositol 3-kinase mutant enhances HER2-mediated transformation by heregulin production and activation of HER3.

ERBB2 ERBB3

1.16e-06238220581867
Pubmed

Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers.

ERBB2 ERBB3

1.16e-06238235108525
Pubmed

Role for HER2/neu and HER3 in fulvestrant-resistant breast cancer.

ERBB2 ERBB3

1.16e-06238217203234
Pubmed

Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling.

ERBB2 ERBB3

1.16e-06238222733765
Pubmed

Vasopressin and oxytocin excite MCH neurons, but not other lateral hypothalamic GABA neurons.

OXT AVP

1.16e-06238222262306
Pubmed

The neurohypophyseal hormones vasopressin and oxytocin. Precursor structure, synthesis and regulation.

OXT AVP

1.16e-0623823768139
Pubmed

Expression of the vasopressin and oxytocin genes in human hypothalami.

OXT AVP

1.16e-0623824065330
Pubmed

The human vasopressin gene is linked to the oxytocin gene and is selectively expressed in a cultured lung cancer cell line.

OXT AVP

1.16e-0623822991279
Pubmed

Zinc finger transcription factors designed for bispecific coregulation of ErbB2 and ErbB3 receptors: insights into ErbB receptor biology.

ERBB2 ERBB3

1.16e-06238216199884
Pubmed

Posttranscriptional upregulation of HER3 by HER2 mRNA induces trastuzumab resistance in breast cancer.

ERBB2 ERBB3

1.16e-06238230068375
Pubmed

HER3 protein expression in relation to HER2 positivity in patients with primary colorectal cancer: clinical relevance and prognostic value.

ERBB2 ERBB3

1.16e-06238225739551
Pubmed

Targeting HER2/HER3 co-mutations in metastatic breast cancer: Case reports of exceptional responders to trastuzumab and pertuzumab therapy.

ERBB2 ERBB3

1.16e-06238238441358
Pubmed

Associations of oxytocin and vasopressin plasma levels with neurocognitive, social cognitive and meta cognitive function in schizophrenia.

OXT AVP

1.16e-06238229609987
Pubmed

Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer.

ERBB2 ERBB3

1.16e-06238210205169
Pubmed

A systematic survey of the intergenic region between the murine oxytocin- and vasopressin-encoding genes.

OXT AVP

1.16e-0623828863731
Pubmed

In situ detection of HER2:HER2 and HER2:HER3 protein-protein interactions demonstrates prognostic significance in early breast cancer.

ERBB2 ERBB3

1.16e-06238221638049
Pubmed

Breast cancer expressing the activated HER2/neu is sensitive to gefitinib in vitro and in vivo and acquires resistance through a novel point mutation in the HER2/neu.

ERBB2 ERBB3

1.16e-06238217638894
Pubmed

Vasopressin and oxytocin in CSF and plasma of patients with aneurysmal subarachnoid haemorrhage.

OXT AVP

1.16e-06238224412107
Pubmed

Synthesis, transport, and release of posterior pituitary hormones.

OXT AVP

1.16e-0623826153132
Pubmed

The anti-HER3 antibody in combination with trastuzumab exerts synergistic antitumor activity in HER2-positive gastric cancer.

ERBB2 ERBB3

1.16e-06238227317872
Pubmed

The contributions of oxytocin and vasopressin pathway genes to human behavior.

OXT AVP

1.16e-06238222245314
Pubmed

The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation.

ERBB2 ERBB3

1.16e-06238212853564
Pubmed

Prognostic implications of altered human epidermal growth factor receptors (HERs) in gastric carcinomas: HER2 and HER3 are predictors of poor outcome.

ERBB2 ERBB3

1.16e-06238221709195
Pubmed

Mothers of autistic children: lower plasma levels of oxytocin and Arg-vasopressin and a higher level of testosterone.

OXT AVP

1.16e-06238224086383
Pubmed

Heart-valve mesenchyme formation is dependent on hyaluronan-augmented activation of ErbB2-ErbB3 receptors.

ERBB2 ERBB3

1.16e-06238212134143
Pubmed

Higher-order association states of cellular ERBB3 probed with photo-cross-linkable aptamers.

ERBB2 ERBB3

1.16e-06238218942860
Pubmed

Influence of perioperative stress on central and peripheral oxytocin and arginine-vasopressin concentrations.

OXT AVP

1.16e-06238231538678
Pubmed

The role of HER2 and HER3 in HER2-amplified cancers beyond breast cancers.

ERBB2 ERBB3

1.16e-06238233907275
Pubmed

Correlation of HER2, p95HER2 and HER3 expression and treatment outcome of lapatinib plus capecitabine in her2-positive metastatic breast cancer.

ERBB2 ERBB3

1.16e-06238222848366
Pubmed

A critical role for HSP90 in cancer cell invasion involves interaction with the extracellular domain of HER-2.

ERBB2 ERBB3

1.16e-06238218056992
Pubmed

HER-2 and HER-3 expression in liver metastases of patients with colorectal cancer.

ERBB2 ERBB3

1.16e-06238225915155
Pubmed

Oxytocin and vasopressin: social neuropeptides with complex neuromodulatory functions.

OXT AVP

1.16e-06238223589638
Pubmed

[Oxytocin and vasopressin: sexual differences and clinical implications].

OXT AVP

1.16e-06238237200960
Pubmed

Co-overexpression of HER2/HER3 is a predictor of impaired survival in breast cancer patients.

ERBB2 ERBB3

1.16e-06238225017122
Pubmed

Pertuzumab counteracts the inhibitory effect of ErbB2 on degradation of ErbB3.

ERBB2 ERBB3

1.16e-06238223698633
Pubmed

Oxytocin and vasopressin genes are significantly associated with schizophrenia in a large Arab-Israeli pedigree.

OXT AVP

1.16e-06238221899794
Pubmed

The significance of ErbB2/3 in the conversion of induced pluripotent stem cells into cancer stem cells.

ERBB2 ERBB3

1.16e-06238235177646
Pubmed

Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas.

ERBB2 ERBB3

1.16e-0623827538656
Pubmed

Pharmacological targeting of the pseudokinase Her3.

ERBB2 ERBB3

1.16e-06238225326665
Pubmed

Impact of HER2 codon 655 polymorphism and expression of HER2 and HER3 in non small cell lung cancer patients.

ERBB2 ERBB3

1.16e-06238226208475
Pubmed

On the nature of oxytocin and vasopressin from human pituitary.

OXT AVP

1.16e-06238213591312
Pubmed

Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1-Mediated Lung Cancer.

ERBB2 ERBB3

1.16e-06238229959202
Pubmed

HER2 expression as a potential marker for response to therapy targeted to the EGFR.

ERBB2 ERBB3

1.16e-06238216622439
Pubmed

ErbB2 and ErbB3 regulate recovery from dextran sulfate sodium-induced colitis by promoting mouse colon epithelial cell survival.

ERBB2 ERBB3

1.16e-06238222157714
Pubmed

Genomic profiling of pleomorphic and florid lobular carcinoma in situ reveals highly recurrent ERBB2 and ERRB3 alterations.

ERBB2 ERBB3

1.16e-06238231932682
Pubmed

Early response to ErbB2 over-expression in polarized Caco-2 cells involves partial segregation from ErbB3 by relocalization to the apical surface and initiation of survival signaling.

ERBB2 ERBB3

1.16e-06238220589763
Pubmed

Neuregulin induces the rapid association of focal adhesion kinase with the erbB2-erbB3 receptor complex in schwann cells.

ERBB2 ERBB3

1.16e-06238210799311
Pubmed

Spontaneous and pronase-induced HER2 truncation increases the trastuzumab binding capacity of breast cancer tissues and cell lines.

ERBB2 ERBB3

1.16e-06238222806884
Pubmed

Marital behavior, oxytocin, vasopressin, and wound healing.

OXT AVP

1.16e-06238220144509
Pubmed

Medial amygdala lesions modify aggressive behavior and immediate early gene expression in oxytocin and vasopressin neurons during intermale exposure.

OXT AVP

1.16e-06238223403283
Pubmed

Oncogenic ERBB3 mutations in human cancers.

ERBB2 ERBB3

1.16e-06238223680147
Pubmed

Carboxyl group footprinting mass spectrometry and molecular dynamics identify key interactions in the HER2-HER3 receptor tyrosine kinase interface.

ERBB2 ERBB3

1.16e-06238223843458
Pubmed

Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity.

ERBB2 ERBB3

1.16e-06238234171264
Pubmed

Design, synthesis and characterization of peptidomimetic conjugate of BODIPY targeting HER2 protein extracellular domain.

ERBB2 ERBB3

1.16e-06238223688700
Pubmed

HER3 intracellular domains play a crucial role in HER3/HER2 dimerization and activation of downstream signaling pathways.

ERBB2 ERBB3

1.16e-06238222983903
Pubmed

HER3 Targeting Sensitizes HNSCC to Cetuximab by Reducing HER3 Activity and HER2/HER3 Dimerization: Evidence from Cell Line and Patient-Derived Xenograft Models.

ERBB2 ERBB3

1.16e-06238227358485
Pubmed

Expression of the arginine vasopressin gene in response to salt loading in oxytocin gene knockout mice.

OXT AVP

1.16e-06238214962074
Pubmed

Regulatory domains in the intergenic region of the oxytocin and vasopressin genes that control their hypothalamus-specific expression in vitro.

OXT AVP

1.16e-06238212944509
Pubmed

Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase.

ERBB2 ERBB3

1.16e-06238221385943
Pubmed

CRISPR-assisted receptor deletion reveals distinct roles for ERBB2 and ERBB3 in skin keratinocytes.

ERBB2 ERBB3

1.16e-06238228805349
Pubmed

Identification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent association.

ERBB2 ERBB3

1.16e-06238212000754
Pubmed

Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3.

ERBB2 ERBB3

1.16e-06238222248472
Pubmed

Hypothalamic vasopressin and oxytocin mRNA expression in relation to depressive state in Alzheimer's disease: a difference with major depressive disorder.

OXT AVP

1.16e-06238219500216
Pubmed

Linking oxytocin and arginine vasopressin signaling abnormalities to social behavior impairments in Prader-Willi syndrome.

OXT AVP

1.16e-06238236113782
Pubmed

Defensive behavioral strategies and enhanced state anxiety during chronic subordinate colony housing are accompanied by reduced hypothalamic vasopressin, but not oxytocin, expression.

OXT AVP

1.16e-06238219120108
Pubmed

Lung tumorigenesis associated with erb-B-2 and erb-B-3 overexpression in human erb-B-3 transgenic mice is enhanced by methylnitrosourea.

ERBB2 ERBB3

1.16e-06238212483526
Pubmed

Inhibition of ErbB-2 and ErbB-3 expression by quercetin prevents transforming growth factor alpha (TGF-alpha)- and epidermal growth factor (EGF)-induced human PC-3 prostate cancer cell proliferation.

ERBB2 ERBB3

1.16e-06238212888923
Pubmed

The Role of Oxytocin and Vasopressin in Drug-Induced Reward-Implications for Social and Non-Social Factors.

OXT AVP

1.16e-06238236979340
Pubmed

Overexpression and gene amplification of EGFR, HER2, and HER3 in biliary tract carcinomas, and the possibility for therapy with the HER2-targeting antibody pertuzumab.

ERBB2 ERBB3

1.16e-06238225112701
Pubmed

Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016.

ERBB2 ERBB3

1.16e-06238214737100
Pubmed

Expression of mutant human epidermal receptor 3 attenuates lung fibrosis and improves survival in mice.

ERBB2 ERBB3

1.16e-06238215731393
Pubmed

Identification of human neurophysins: complete amino acid sequences of MSEL- and VLDV-neurophysins.

OXT AVP

1.16e-0623826574452
Pubmed

Overexpression of ErbB2 and ErbB3 receptors in Schwann cells of patients with Charcot-Marie-tooth disease type 1A.

ERBB2 ERBB3

1.16e-06238216307437
Pubmed

Functional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells.

ERBB2 ERBB3

1.16e-06238216168116
Pubmed

Increased erbB3 promotes erbB2/neu-driven mammary tumor proliferation and co-targeting of erbB2/erbB3 receptors exhibits potent inhibitory effects on breast cancer cells.

ERBB2 ERBB3

1.16e-06238226261492
Pubmed

Mechanistic Investigations of Diarrhea Toxicity Induced by Anti-HER2/3 Combination Therapy.

ERBB2 ERBB3

1.16e-06238229654069
Pubmed

Ontogeny of the vasopressin and oxytocin RNAs in the mouse hypothalamus.

OXT AVP

1.16e-0623829678638
Pubmed

Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.

ERBB2 ERBB3

1.16e-06238229338072
Pubmed

Sociality, pathogen avoidance, and the neuropeptides oxytocin and arginine vasopressin.

OXT AVP

1.16e-06238221960250
Pubmed

Engineering of a bispecific affibody molecule towards HER2 and HER3 by addition of an albumin-binding domain allows for affinity purification and in vivo half-life extension.

ERBB2 ERBB3

1.16e-06238224678002
Pubmed

Comparison of vasopressin and oxytocin expressions in the hypothalamo-neurohypophysial system of patients with chronic heart failure.

OXT AVP

1.16e-06238219672816
Pubmed

HER family receptor abnormalities in lung cancer brain metastases and corresponding primary tumors.

ERBB2 ERBB3

1.16e-06238219622585
Pubmed

Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted Therapies.

ERBB2 ERBB3

1.16e-06238226138066
Pubmed

Identification of patients with transitional cell carcinoma of the bladder overexpressing ErbB2, ErbB3, or specific ErbB4 isoforms: real-time reverse transcription-PCR analysis in estimation of ErbB receptor status from cancer patients.

ERBB2 ERBB3

1.16e-06238214614020
Pubmed

The protein tyrosine kinase family of the human genome.

EPHB4 ERBB2 ERBB3 TIE1

2.09e-068338411114734
Pubmed

Notch signaling is essential for ventricular chamber development.

EPHB4 ERBB2 ERBB3

3.46e-062738317336907
Pubmed

NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies.

ERBB2 ERBB3

3.48e-06338226770651
Pubmed

EGFR, HER2, and HER3 protein expression in paired primary tumor and lymph node metastasis of colorectal cancer.

ERBB2 ERBB3

3.48e-06338235902718
Pubmed

[Correlation of epidermal growth factor receptor mutations and HER2/3 protein expression with clinical outcome in advanced non-small cell lung cancer patients treated with gefitinib].

ERBB2 ERBB3

3.48e-06338220038315
Pubmed

Growth stimulation of non-small cell lung cancer cell lines by antibody against epidermal growth factor receptor promoting formation of ErbB2/ErbB3 heterodimers.

ERBB2 ERBB3

3.48e-06338217426253
Pubmed

Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1, 2 and 3 in Periampullary Adenocarcinoma.

ERBB2 ERBB3

3.48e-06338227070783
Pubmed

HER2 regulates cancer stem-like cell phenotype in ALK translocated NSCLC.

ERBB2 ERBB3

3.48e-06338228656214
Pubmed

Specific antibodies and sensitive immunoassays for the human epidermal growth factor receptors (HER2, HER3, and HER4).

ERBB2 ERBB3

3.48e-06338228653892
Pubmed

Role of HER3 expression and PTEN loss in patients with HER2-overexpressing metastatic breast cancer (MBC) who received taxane plus trastuzumab treatment.

ERBB2 ERBB3

3.48e-06338224346286
Pubmed

A central role for HER3 in HER2-amplified breast cancer: implications for targeted therapy.

ERBB2 ERBB3

3.48e-06338218632642
Pubmed

Plasma concentrations of peptide hormones: Unrealistic levels of vasopressin (AVP), oxytocin (OXT), and brain natriuretic peptide (BNP).

OXT AVP

3.48e-06338239034759
Pubmed

Antibody targeting of HER2/HER3 signaling overcomes heregulin-induced resistance to PI3K inhibition in prostate cancer.

ERBB2 ERBB3

3.48e-06338225471734
Pubmed

EGFR/ERBB receptors differentially modulate sebaceous lipogenesis.

ERBB2 ERBB3

3.48e-06338225889637
InteractionFBLN2 interactions

ZNF696 LAMA5 LAMC2 ZNF865

7.12e-0666384int:FBLN2
InteractionSLA2 interactions

LAMC2 ERBB2 ERBB3

1.22e-0524383int:SLA2
CytobandXp22

PPEF1 EGFL6

1.98e-0425382Xp22
CytobandEnsembl 112 genes in cytogenetic band chrXp22

ARSD PPEF1 EGFL6

1.17e-03250383chrXp22
Cytoband17p13.3

C1QBP ANKFY1

2.44e-038838217p13.3
Cytoband17q12

ERBB2 SOCS7

3.08e-039938217q12
Cytoband17q25.3

FAAP100 TMC6

3.20e-0310138217q25.3
Cytoband20p13

OXT AVP

3.26e-0310238220p13
CytobandEnsembl 112 genes in cytogenetic band chr20p13

OXT AVP

4.70e-03123382chr20p13
CytobandEnsembl 112 genes in cytogenetic band chr17q12

ERBB2 SOCS7

6.81e-03149382chr17q12
GeneFamilyErb-b2 receptor tyrosine kinases

ERBB2 ERBB3

1.39e-0542821096
GeneFamilyLaminin subunits

LAMA5 LAMC2

1.51e-0412282626
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

MEGF10 STAB1

7.93e-04272821253
GeneFamilyFibronectin type III domain containing

EPHB4 TIE1 TNC

1.89e-03160283555
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA5 CRELD1 LAMC2 SSPOP CRISPLD1 TNC SVEP1

1.02e-08191387MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA5 CRELD1 LAMC2 SSPOP CRISPLD1 TNC SVEP1

1.22e-08196387M3008
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN

EPHB4 FZD8 LAMA5 ERBB2 TIE1 STAB1

4.02e-08135386M5825
CoexpressionNABA_CORE_MATRISOME

LAMA5 CRELD1 LAMC2 SSPOP CRISPLD1 TNC SVEP1

1.09e-07270387MM17057
CoexpressionNABA_CORE_MATRISOME

LAMA5 CRELD1 LAMC2 SSPOP CRISPLD1 TNC SVEP1

1.24e-07275387M5884
CoexpressionNABA_MATRISOME

LAMA5 CRELD1 LAMC2 SSPOP CRISPLD1 TNC SVEP1 MEGF10 EGFL6 WIF1

1.20e-0610083810MM17056
CoexpressionNABA_MATRISOME

LAMA5 CRELD1 LAMC2 SSPOP CRISPLD1 TNC SVEP1 MEGF10 EGFL6 WIF1

1.41e-0610263810M5889
CoexpressionRELA_DN.V1_DN

ECEL1 OXT CLCN1 AVP EGFL6

1.70e-06139385M2695
CoexpressionNABA_MATRISOME_BLEO_FIBROTIC_LUNG

LAMA5 LAMC2 TNC

3.15e-0620383MM17053
CoexpressionWAMUNYOKOLI_OVARIAN_CANCER_LMP_UP

EPHB4 ERBB3 ARSD FAAP100 TMC6

4.25e-05270385M19982
CoexpressionLIM_MAMMARY_STEM_CELL_UP

FZD8 TIE1 CRISPLD1 SVEP1 WIF1 PKD1

6.07e-05479386M2573
CoexpressionLIM_MAMMARY_STEM_CELL_UP

FZD8 TIE1 CRISPLD1 SVEP1 WIF1 PKD1

6.35e-05483386MM1082
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

KCNQ2 LAMC2 ERBB2 ERBB3 MYO16 SVEP1 TMC6 WIF1

1.26e-041074388M1941
CoexpressionGSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY15_EFFECTOR_CD8_TCELL_DN

LAMA5 SERTAD4-AS1 AVP FAAP100

1.50e-04186384M9510
CoexpressionGU_PDEF_TARGETS_UP

FZD8 LAMC2 TNC

1.50e-0471383M3955
CoexpressionDEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP

EPHB4 CRELD1 ERBB3 FCGBP PKD1

1.82e-04368385M16431
CoexpressionAtlasStromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4

EPHB4 TIE1 TNC STAB1

2.08e-0591384GSM777059_100
CoexpressionAtlasStromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4

EPHB4 TIE1 TNC STAB1

2.57e-0596384GSM777063_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#3_top-relative-expression-ranked_500

CRISPLD1 MEGF10 EGFL6 WIF1

3.39e-05103384gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#4_top-relative-expression-ranked_1000

CRISPLD1 TNC MEGF10 WIF1

1.36e-04147384DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k4_1000
ToppCellAT1-AT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

KCNQ2 LAMC2 ECEL1 CRISPLD1 TNC

2.59e-0716238557d627259d27f39885bf416d74bcb6656db6e27b
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LAMA5 ERBB2 ERBB3 ARSD TNC

7.36e-0720038597f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FZD8 CRISPLD1 TNC SVEP1 WIF1

7.36e-07200385a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellGlobus_pallidus|World / BrainAtlas - Mouse McCarroll V32

ECEL1 OXT AVP PKD1

4.02e-0612638444b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FZD8 ERBB3 TIE1 MYO16

8.67e-0615338461fe71e32fc9c8cad875bc087aad0b0ff680bf45
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LAMA5 FBXL17 ERBB3 WIF1

1.20e-0516638489e2b8453180983533faccb4275867861876d7ee
ToppCellwk_20-22-Mesenchymal-Chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FZD8 CRISPLD1 TNC WIF1

1.34e-05171384d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FZD8 LAMA5 LAMC2 ERBB3

1.44e-051743842cd6638b361ca05ab83d09ce657194aed97873b7
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

FZD8 LAMA5 LAMC2 ERBB2

1.61e-051793841603117b52623663458a977c94bf7f9f6c1114b8
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANKFY1 RAPGEF6 FCGBP TIE1

1.61e-0517938406d412fc096d88de168969466ce422f0ab5553b2
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMA5 LAMC2 ERBB2 ERBB3

1.61e-05179384d5763912a4ce7188535675e338799b856edb9dda
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FZD8 ERBB3 ECEL1 MEGF10

1.68e-05181384fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCellwk_15-18-Epithelial-PNS-Early_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KCNQ2 ERBB3 ECEL1 MEGF10

1.75e-051833847e8366ec8117d36cec67f77dcb0e9a6032d87fcb
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPEF1 TNC MEGF10 WIF1

1.75e-05183384f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCelldroplet-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 TIE1 CRISPLD1 STAB1

1.83e-05185384eeb6f55a6f79adf80247baa2c4b0df44553557ad
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNQ2 ERBB3 PPEF1 MEGF10

1.91e-05187384dfc2b95d70daf533bc0cc4ce78af9f65dd75a25b
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMA5 LAMC2 MYO16 WIF1

1.91e-051873844ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCellControl-Epithelial-ATI|Control / Disease state, Lineage and Cell class

LAMA5 LAMC2 ERBB3 MYO16

1.91e-05187384fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCellIPF-Epithelial-Aberrant_Basaloid|IPF / Disease state, Lineage and Cell class

LAMA5 LAMC2 ERBB3 TNC

1.91e-0518738419d6a404fc3651d98a93e3848e372df51a239c57
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)|368C / Donor, Lineage, Cell class and subclass (all cells)

FZD8 LAMA5 ERBB2 ERBB3

1.95e-051883849155b9a92496e75646778c025b02947e9e9ec73a
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMA5 LAMC2 MYO16 WIF1

1.95e-05188384eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)-|368C / Donor, Lineage, Cell class and subclass (all cells)

FZD8 LAMA5 ERBB2 ERBB3

1.95e-05188384c74771584b3ba9561a99a54bf55a9203ddf8eff8
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

EPHB4 LAMA5 TIE1 STAB1

1.99e-051893849a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCellIPF-Epithelial-Aberrant_Basaloid|World / Disease state, Lineage and Cell class

LAMA5 LAMC2 ERBB3 TNC

1.99e-051893848030a353473da34ae92429f2d822171a2e94248f
ToppCellwk_08-11-Epithelial-PNS-Schwann_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KCNQ2 ERBB3 ECEL1 MEGF10

2.03e-051903844a777d8aa19cadd3b61b023772df142421a89113
ToppCellLAM-Epithelial-AT1|LAM / Condition, Lineage and Cell class

LAMA5 LAMC2 ERBB2 ERBB3

2.08e-0519138466875b2ec2c510489407f3e433a90cdf74a15094
ToppCelldroplet-Lung-LUNG-1m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 FZD8 TIE1 CRISPLD1

2.08e-05191384c379a499dabf3c9ed80f47adbb2d949821c5b053
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SERTAD4-AS1 CRISPLD1 MEGF10 WIF1

2.08e-05191384f9a46956778a8773d6656340ecf5d218376d79c2
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 FZD8 TIE1 CRISPLD1

2.08e-051913849fc674a58f20b47255e4457d5195c8cff17b0414
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB4 FZD8 TIE1 CRISPLD1

2.12e-051923841990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB4 FZD8 TIE1 CRISPLD1

2.12e-05192384845cc9c18b4436b07dd3ce7980052683937546d2
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD1 TNC EGFL6 WIF1

2.12e-05192384b35f0e422070ba9c7c1d9ff3eace4edc10286cde
ToppCellEC|World / Lineage and Cell class

EPHB4 LAMA5 TIE1 STAB1

2.12e-05192384478866dd5b0d6ff3a76d07a17c4b5989dd7a27bb
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB4 FZD8 TIE1 CRISPLD1

2.12e-05192384c72a082c93a8825adbfef37f889ba3a7052f201b
ToppCellnormal_Lung-Epithelial_cells-AT1|normal_Lung / Location, Cell class and cell subclass

LAMA5 LAMC2 ERBB2 ERBB3

2.25e-05195384569d1ebc5a5aa110a2430b096755ae35354040c4
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Club|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB2 ERBB3 FCGBP SOCS7

2.25e-05195384b9e8f405f6d837bb39b615836d3e2df349737c0e
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_II_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LAMA5 LAMC2 ERBB3 WIF1

2.25e-051953840e3aac1b1a1fd483f5fb9a394eb90c0e1ce63542
ToppCell(7)_Epithelial-I_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

LAMA5 LAMC2 ERBB2 ERBB3

2.30e-05196384150554fa06868d29b0608189862eef6505ba757f
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMC2 CRISPLD1 MEGF10 WIF1

2.34e-05197384f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

EPHB4 LAMA5 SERTAD4-AS1 TIE1

2.34e-051973847caa2c86dc4d50b57a7db8f7278d1588282ad6db
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNC SVEP1 MEGF10 EGFL6

2.34e-05197384c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

EPHB4 LAMA5 SERTAD4-AS1 TIE1

2.34e-05197384951f18f326967206adbbfc422cce9eea3d2e0854
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD1 TNC EGFL6 WIF1

2.34e-05197384cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TNC SVEP1 MEGF10 WIF1

2.34e-051973842f72fd9a5b6d62c24a95ed2246194ea7458c0f12
ToppCellAT1-AT2_cells|World / lung cells shred on cell class, cell subclass, sample id

LAMA5 LAMC2 ERBB2 ERBB3

2.39e-05198384a5b3617ea2ed4bffba59edcf6284799c2b3bbb29
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB2 ERBB3 FCGBP OXT

2.39e-051983845dd2aa7684c36beffa204ca4c04d0501cabac10f
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMC2 ERBB3 TNC WIF1

2.39e-05198384aed0476248e9637897eefb1623ec4035f2dacd82
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMC2 ERBB3 TNC WIF1

2.39e-05198384691a2f1779225e5519155460eeb6a2aac5f67a92
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

LAMC2 ERBB3 TNC WIF1

2.39e-05198384e115eea04012e9e492e923ed080e1723c38d14fd
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LAMC2 ERBB3 TNC WIF1

2.39e-0519838433d1e0b6f57663544bee0ffdde83a65da764d44c
ToppCellSevere_COVID-19-Epithelial-AT1/AT2|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

LAMC2 ERBB3 TNC WIF1

2.39e-0519838443e33d28d9de5033bd00d39be953542a225236ed
ToppCellwk_15-18-Epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LAMA5 LAMC2 ERBB3 WIF1

2.39e-0519838412bbe77c3d68bf1e545949dbb1eb49ed3641de3d
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

CRISPLD1 MYO16 SVEP1 WIF1

2.39e-051983840c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellnormal_Lung-Fibroblasts-Smooth_muscle_cells|Fibroblasts / Location, Cell class and cell subclass

LAMA5 TNC EGFL6 WIF1

2.44e-05199384d65847ceb68a560798df3f73e6f838e7c3e38a1c
ToppCelltumor_Lung-Epithelial_cells-tS2|tumor_Lung / Location, Cell class and cell subclass

LAMC2 ERBB2 ERBB3 TNC

2.44e-0519938428ec59e01061287fb0892491790b316e2b93e232
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-AT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA5 LAMC2 ERBB2 ERBB3

2.44e-05199384aca81a879ef9c196bd1885eff4c63ffe6c9682b7
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ERBB2 ERBB3 MEGF10 WIF1

2.44e-051993843e35ee426ef06f9af568c37349b62dd1ee9b97ea
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD1 TNC EGFL6 WIF1

2.44e-05199384edd5300da1a3b758210ff8f949e9d1988b8bc7e2
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERBB2 ERBB3 MEGF10 WIF1

2.44e-05199384f8846446ebbc4948cdc69640782db1358bbdc486
ToppCellParenchyma_COVID-19-Epithelial-TX-AT1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ERBB2 ERBB3 MEGF10 WIF1

2.44e-05199384fe9f5bc317be0c35bd96311bf0b3c7b91d98acc5
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LAMA5 LAMC2 ERBB2 ERBB3

2.48e-052003845f7e8d8b05c90a10313775f9f126eb4ab0fe4f67
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNC SVEP1 MEGF10 EGFL6

2.48e-05200384ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMA5 LAMC2 ERBB2 ERBB3

2.48e-05200384c6f211bbadd0c9be776c58807249e06764df47dc
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LAMA5 LAMC2 ERBB2 ERBB3

2.48e-05200384e3a80626941363bfc9d97ef906d38c97080aecb1
ToppCellBiopsy_Other_PF-Epithelial-Transitional_AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

LAMA5 LAMC2 ERBB3 WIF1

2.48e-052003841ba6327851aa61e9a1f1fe1671bc27929d93ac74
ToppCellBiopsy_Other_PF-Epithelial|Biopsy_Other_PF / Sample group, Lineage and Cell type

LAMC2 ERBB2 ERBB3 WIF1

2.48e-052003841ef4d5ae698fa721e0f510bf0d918bd8d3b00591
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ERBB3 FCGBP AVP

2.80e-05693833da27f504e82277fa4a8fb67d60fc26dee0a414f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ECEL1 TNC MEGF10

8.75e-051013836523c314166dcf66c3ed13c02ca4b886b068e5b8
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ECEL1 TNC MEGF10

9.27e-05103383d8965b338b90ddc0686ea0d94e9a330128566c39
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Itih5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAMA5 TNC MEGF10

1.32e-04116383605bd4fdf547cc41783e99cd78425760ef6461ef
ToppCelldroplet-Skin-nan-18m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNC MYO16 SVEP1

1.53e-041223838f675dc341b3f6e22f7e52c34d167d9e37df0982
ToppCelldroplet-Skin-nan-18m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNC MYO16 SVEP1

1.53e-04122383c7e81504e62d132624ec15b7d38dc5b6493a37a4
ToppCellCOVID-19_Mild-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

CRISPLD1 MYO16 SVEP1

1.61e-041243835ef9eb806fb2c8ee5aae0a75503d244b08ee10d4
ToppCelldroplet-Skin-nan-18m|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNC MYO16 SVEP1

1.64e-041253835a309ce803d2b8efd791eb21808121bf5fc3ea8e
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCNQ2 MYO16 SVEP1

1.64e-04125383b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CRISPLD1 MYO16 SVEP1

1.68e-041263836cb89754010d64875e115da6c5805efac7a4a82d
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CRISPLD1 MYO16 SVEP1

1.68e-0412638369b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT1_-_meso|E18.5-samps / Age Group, Lineage, Cell class and subclass

LAMA5 LAMC2 ERBB3

2.39e-0414238377fd145c1c500d580f70ac4e54c3fd879ecf0ab3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TNC SVEP1 WIF1

2.81e-041503837a9d6a7ff8000e9a061e1b586e4c258cc91a2a09
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TNC SVEP1 WIF1

2.81e-04150383e5b843cb2bc847f6cab4cbec0a2a6a72fac50fee
ToppCellURO-Lymphocyte-T_NK-CD4_Naive|URO / Disease, Lineage and Cell Type

OXT AVP MYO16

3.04e-041543836c214ad5cbbfa8bab3f76b593cb598dfb914b566
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ECEL1 PPEF1 PKD1

3.21e-04157383f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCellAT1-AT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

LAMC2 ERBB3 MYO16

3.28e-041583833bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

LAMA5 FBXL17 STAB1

3.34e-0415938324f87c666eff10c1844c900ffd7ad49fa9f80481
ToppCellClub_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ERBB2 ERBB3 SOCS7

3.34e-04159383a7bcff268b1962a561fd2848e01ae16565bce895
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA5 ERBB2 SOCS7

3.34e-041593838680b054622f573a82b1625fb93c2d5db81d1034
ToppCellNS-critical-d_16-33-Myeloid-Mast_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TIE1 MYO16 STAB1

3.40e-04160383c61869d9dbba250270e59366e15af204e5b4395d
ToppCellNS-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

OXT TIE1 MYO16

3.40e-041603838a4746463ca1976f7d6de803496c851249ced797
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC2 FCGBP TNC

3.52e-0416238325323785dd33337bcefd05958a4a1a208a9ceb04
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC2 FCGBP TNC

3.52e-041623833dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCellfacs-Thymus-Epithelium-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC2 FCGBP TNC

3.52e-041623830a7138266054ea5954649c8b61ef93905d56b068
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

LAMA5 ERBB3 WIF1

3.52e-041623832259e9536147e9cdee772e3a30ba7d104573262c
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

FZD8 ERBB2 SVEP1

3.65e-04164383d7053de88ef8e42cac6726a40e72f212659ee034
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERBB3 PPEF1 MEGF10

3.65e-0416438357301178e420983c0cb72178e288a3a0449fdda3
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-MEP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

C1QBP TIE1 AVP

3.65e-0416438347355439e578d1b1a387fb4ee761162028abea4a
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC2 ERBB3 MYO16

3.78e-0416638311b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC2 ERBB3 MYO16

3.78e-04166383fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCellwk_20-22-Epithelial-Airway_epithelial_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LAMA5 ERBB3 WIF1

3.78e-04166383fcd0bd70b553789092249806ace324b77bd10481
ToppCellwk_20-22-Epithelial-Airway_epithelial_progenitor-epi-stalk_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LAMA5 ERBB3 WIF1

3.78e-04166383b60954e5625743657d0fd9264b738b46e72fd8a6
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERBB3 ECEL1 MEGF10

3.85e-0416738349b19159c62d33d65ed1e59a148c11ae902fd41c
DrugPramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; HL60; HT_HG-U133A

ZNF696 ERBB2 ANKFY1 FAAP100 SVEP1 SOCS7

9.04e-071993862198_UP
DrugDemoxytocin

OXT AVP

2.71e-062382CID000008229
DrugAC1NURZQ

OXT AVP

2.71e-062382CID005490952
DrugP9-28

OXT AVP

2.71e-062382CID000139428
DrugPro-arg-gly-amide

OXT AVP

2.71e-062382CID000170777
Drug2-phenylalanine

OXT AVP

2.71e-062382CID000031722
DrugPhasvatocin

OXT AVP

2.71e-062382CID000192334
Drugethyl cyclohexylideneacetate

OXT AVP

2.71e-062382CID000073776
DrugCgp 29325

OXT AVP

2.71e-062382CID000175772
DrugGlumitocin

OXT AVP

2.71e-062382CID003084054
Drugcolchine

LAMA5 LAMC2 ECEL1 OXT AVP TNC PKD1

2.91e-06383387CID000002833
DrugAC1O4Q3H

OXT AVP

8.13e-063382CID006410744
Drug2-acetamidoethanethiol

ERBB2 ERBB3

8.13e-063382ctd:C023704
Drugranatensin C

OXT AVP

8.13e-063382CID005488559
DrugAnnetocin

OXT AVP

8.13e-063382CID000197651
DrugL 366811

OXT AVP

8.13e-063382CID003083084
DrugdE-Vvt

OXT AVP

8.13e-063382CID003083171
DrugAC1L45X9

OXT AVP

8.13e-063382CID000151233
DrugL 366682

OXT AVP

8.13e-063382CID000196819
DrugD-3250

ERBB2 AVP

8.13e-063382CID004124837
DrugDglvp

OXT AVP

8.13e-063382CID000169434
DrugAsvatocin

OXT AVP

8.13e-063382CID000192333
DrugSikvav

LAMA5 LAMC2 TNC

8.47e-0624383CID005487517
DrugNSC 714187

LAMA5 LAMC2 ERBB3 PPEF1

1.21e-0585384CID005288693
DrugPhenypressin

OXT AVP

1.62e-054382CID003082314
DrugPressinamide

OXT AVP

1.62e-054382CID003082272
DrugDpvdavp

OXT AVP

1.62e-054382CID003081540
DrugVasotocin

OXT AVP

1.62e-054382ctd:D014668
DrugZ-PLG

OXT AVP

1.62e-054382CID000151917
DrugConopressin G

OXT AVP

1.62e-054382CID000163847
DrugMpomeovt

OXT AVP

2.70e-055382CID000122244
DrugTgot

OXT AVP

2.70e-055382CID003082106
DrugAGN 190851

OXT AVP

2.70e-055382CID000131829
DrugL 365209

OXT AVP

2.70e-055382CID000196774
DrugFelypressin

OXT AVP

2.70e-055382CID000005956
DrugMifepristone

LAMA5 LAMC2 ERBB3 OXT TNC SVEP1 WIF1

3.15e-05553387ctd:D015735
DrugB-Ms

LAMA5 LAMC2 ERBB2 TNC

3.86e-05114384CID000445091
DrugL-366,509

OXT AVP

4.05e-056382CID003083288
Drug5-methoxy-N-isobutanoyltryptamine

OXT AVP

4.05e-056382CID006455231
DrugL-371,257

OXT AVP

4.05e-056382CID006918320
DrugD3PVP

OXT AVP

4.05e-056382CID000195824
Drugoxypressin

OXT AVP

4.05e-056382CID000164712
DrugZD-6

ERBB2 ERBB3

4.05e-056382CID010062753
DrugDeavp

OXT AVP

4.05e-056382CID000114715
DrugIEM-611

OXT AVP

5.67e-057382CID000039794
DrugB3852

OXT AVP

5.67e-057382CID000086074
DrugVdavp

OXT AVP

5.67e-057382CID000171113
Drugimatinib

EPHB4 FZD8 ERBB2 ERBB3 TIE1 AVP

7.25e-05430386CID000005291
Drugisovaleramide

KCNQ2 AVP

7.55e-058382CID000010930
DrugL 366948

OXT AVP

7.55e-058382CID000188397
DrugFolfox protocol

ERBB2 ERBB3

7.55e-058382ctd:C410216
DrugCI-1033

EPHB4 ERBB2 ERBB3

9.49e-0553383CID000156413
DrugCp 14

OXT AVP

9.69e-059382CID005487244
DrugAC1MIZWH

OXT AVP

9.69e-059382CID003083001
Drugpyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid

OXT AVP

9.69e-059382ctd:C077792
Drugd(CH2)5-Davp

OXT AVP

9.69e-059382CID000123750
DrugMcp-tva-argipressin

OXT AVP

9.69e-059382CID000122322
DrugHydrin 1

OXT AVP

9.69e-059382CID000195374
DrugA-state

ERBB2 TNC

9.69e-059382CID005460479
DrugLMWH

LAMA5 KCNQ2 LAMC2 ERBB3 OXT AVP TNC

9.89e-05663387CID000000772
DrugAC1L3JHX

C1QBP ERBB2 ERBB3 PKD1

1.01e-04146384CID000090206
Drugkalinin

LAMA5 LAMC2 TNC

1.06e-0455383CID000032518
DrugBay K 8644

ECEL1 OXT AVP PKD1

1.12e-04150384CID000002303
DrugDuratocin

OXT AVP

1.21e-0410382CID000071715
DrugJTP 4819

OXT AVP

1.21e-0410382ctd:C094211
Drug6-(methylamino)pyrido(3,4-d)pyrimidine

ERBB2 ERBB3

1.21e-0410382ctd:C107875
Drugcyclo(Leu-Gly)

OXT AVP

1.21e-0410382CID000002902
DrugAC1MIWZV

OXT AVP

1.21e-0410382CID003081474
DrugAC1L9INI

LAMA5 LAMC2 TNC

1.31e-0459383CID000445839
DrugLG 5

LAMA5 LAMC2 ERBB3

1.37e-0460383CID011840957
DrugAC1L1G72

LAMA5 LAMC2

1.48e-0411382CID000003553
DrugBE-23372M

ERBB2 ERBB3

1.48e-0411382CID005311105
DrugBM165

LAMA5 LAMC2

1.48e-0411382CID003352881
DrugDpmetyravp

OXT AVP

1.48e-0411382CID000119517
Drug1-adamantaneacetic acid

OXT AVP

1.77e-0412382CID000123221
Drugsulmazole

ECEL1 TNC

1.77e-0412382CID000005353
DrugP-14

C1QBP ERBB2 TMC6 WIF1

1.90e-04172384CID000017957
DrugCMF regimen

ERBB2 ERBB3

2.09e-0413382ctd:C034456
DrugAC1MIYR4

OXT AVP

2.09e-0413382CID003082393
Drug2-thiazolylethylamine

OXT AVP

2.44e-0414382CID000087653
DrugOvta

OXT AVP

2.44e-0414382CID003081047
DrugAC1NFF1B

OXT AVP

2.44e-0414382CID004657542
DrugUtedrin

OXT AVP

2.44e-0414382CID000005771
DrugA0395

LAMA5 LAMC2 ERBB2

2.67e-0475383CID009906466
DrugCloralosa

OXT AVP TNC

2.77e-0476383CID000027525
DrugNVP-TAE684

ERBB2 ERBB3

2.81e-0415382ctd:C516714
Drug2-amino-5-methylpyridine

LAMA5 LAMC2 ERBB3

2.88e-0477383CID000015348
DrugVitamin K2 [11032-49-8]; Up 200; 9uM; MCF7; HT_HG-U133A

ANKFY1 ARSD SVEP1 EGFL6

2.95e-041933843880_UP
Drugnordihydroguaiaretic acid; Down 200; 1uM; PC3; HT_HG-U133A

EPHB4 ZNF696 LAMA5 FAAP100

3.01e-041943841223_DN
DrugTadjakonine [11087-94-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A

LAMC2 ECEL1 CLCN1 SOCS7

3.07e-041953844424_UP
DrugCyclacillin [3485-14-1]; Up 200; 11.8uM; PC3; HT_HG-U133A

EPHB4 SOCS7 WIF1 STAB1

3.07e-041953843800_UP
DrugSolanine alpha [20562-02-1]; Up 200; 4.6uM; HL60; HT_HG-U133A

LAMC2 ERBB2 ERBB3 TNC

3.07e-041953842152_UP
DrugGemfibrozil [25812-30-0]; Down 200; 16uM; PC3; HT_HG-U133A

CRELD1 LAMC2 ANKFY1 TNC

3.13e-041963845069_DN
DrugAlcuronium chloride [15180-03-7]; Up 200; 5.4uM; MCF7; HT_HG-U133A

LAMC2 ANKFY1 SVEP1 SOCS7

3.13e-041963844409_UP
DrugDeptropine citrate [2169-75-7]; Up 200; 7.6uM; HL60; HT_HG-U133A

EPHB4 ZNF696 FAAP100 TNC

3.13e-041963843144_UP
DrugBudesonide [51333-22-3]; Down 200; 9.2uM; PC3; HT_HG-U133A

EPHB4 FZD8 ZXDC ERBB2

3.13e-041963846330_DN
DrugDropropizine (R,S) [17692-31-8]; Up 200; 17uM; PC3; HT_HG-U133A

ZXDC LAMC2 ARSD TMC6

3.19e-041973845106_UP
DrugFludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A

ZNF696 LAMC2 ERBB3 STAB1

3.19e-041973842328_UP
Drug3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; MCF7; HT_HG-U133A

LAMC2 PPEF1 SVEP1 EGFL6

3.19e-041973843382_UP
Drugbenzanilide

KCNQ2 AVP

3.21e-0416382CID000007168
DiseaseDysmenorrhea

OXT AVP

1.61e-062382C0013390
DiseaseHyponatremia

OXT AVP

9.67e-064382C0020625
DiseasePolyuria

OXT AVP

1.61e-055382C0032617
Diseaseoxytocin-neurophysin 1 measurement

OXT AVP

2.41e-056382EFO_0802839
DiseaseHead and Neck Carcinoma

ERBB2 ERBB3

7.22e-0510382C3887461
Diseasecystic kidney disease (implicated_via_orthology)

EPHB4 LAMA5

7.22e-0510382DOID:2975 (implicated_via_orthology)
Diseasegallbladder neoplasm

ERBB2 ERBB3

8.82e-0511382C0016978
DiseaseMalignant neoplasm of gallbladder

ERBB2 ERBB3

8.82e-0511382C0153452
DiseaseSchizophrenia

KCNQ2 ERBB3 RAPGEF6 OXT AVP MYO16 MEGF10

1.18e-04883387C0036341
Diseasemedian neuropathy (biomarker_via_orthology)

ERBB2 ERBB3

1.46e-0414382DOID:571 (biomarker_via_orthology)
DiseaseBenign neoplasm of stomach

ERBB2 ERBB3

2.17e-0417382C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ERBB2 ERBB3

2.17e-0417382C0496905
DiseaseCarcinoma in situ of stomach

ERBB2 ERBB3

2.17e-0417382C0154060
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

ERBB2 ERBB3

2.72e-0419382DOID:2876 (is_marker_for)
DiseaseStomach Carcinoma

ERBB2 ERBB3

3.34e-0421382C0699791
Diseaseurinary bladder cancer (is_marker_for)

ERBB2 ERBB3 WIF1

3.57e-04107383DOID:11054 (is_marker_for)
DiseaseNasopharyngeal carcinoma

ERBB2 ERBB3

3.67e-0422382C2931822
Diseasestomach carcinoma (is_marker_for)

ERBB2 ERBB3

4.38e-0424382DOID:5517 (is_marker_for)
DiseaseStomach Neoplasms

ERBB2 ERBB3 FCGBP WIF1

5.67e-04297384C0038356
DiseaseMalignant neoplasm of stomach

ERBB2 ERBB3 FCGBP WIF1

5.89e-04300384C0024623
DiseaseIschemia

OXT AVP

5.98e-0428382C0022116
DiseaseCarcinoma, Ovarian Epithelial

ERBB2 SOCS7

6.87e-0430382C4721610
Diseaseintestinal cancer (implicated_via_orthology)

ERBB2 ERBB3

7.82e-0432382DOID:10155 (implicated_via_orthology)
DiseaseHead and Neck Neoplasms

ERBB2 ERBB3

8.31e-0433382C0018671
Diseasenephroblastoma (is_marker_for)

ERBB2 WIF1

8.83e-0434382DOID:2154 (is_marker_for)
Diseaseductal carcinoma in situ (is_marker_for)

ERBB2 ERBB3

1.16e-0339382DOID:0060074 (is_marker_for)
DiseaseDisease Exacerbation

LAMC2 ERBB2 ERBB3

1.25e-03165383C0235874

Protein segments in the cluster

PeptideGeneStartEntry
AGGCARCKGPLPTDC

ERBB2

221

P04626
EPCGGLCPKACEGTG

ERBB3

321

P21860
GAGACYGRGVCPCSG

ARSD

491

P51689
FGECVGPNKCRCFPG

EGFL6

71

Q8IUX8
PGLLRPRGPCACGCG

C1QBP

56

Q07021
GCDATCWGPGPGGCL

ANKFY1

711

Q9P2R3
GTVCGQPCPEGRFGK

MEGF10

261

Q96KG7
CMGAGPGRCKKCSPG

CRELD1

281

Q96HD1
CRECRPGGSCAPCGG

EPHB4

361

P54760
KCCLPDDGGPGAGSF

MYO16

1436

Q9Y6X6
SKGSPCRGPLCGCCP

KCNQ2

416

O43526
FDGCGGCRPCACGPA

LAMA5

2061

O15230
YCLPGPVLCAACGGG

FAAP100

341

Q0VG06
GGGACPEGCPERKAF

ECEL1

91

O95672
PGGGAAPCEPGCQCR

FZD8

221

Q9H461
GGAQGCGECVSKPCP

FCGBP

3436

Q9Y6R7
SKGCGEGCGPQGCPV

FCGBP

5021

Q9Y6R7
GRPCSACPPSFGGGC

CRISPLD1

221

Q9H336
ACTPCKQPRCGGGGC

FBXL17

206

Q9UF56
GGSKGGCGSSCCVPV

KRTAP5-3

81

Q6L8H2
RSDGTCVCKPGFGGP

LAMC2

586

Q13753
PGRGCGPCEPPCLCG

PKD1

26

P98161
GKNGCFPNTCRGGGC

PPEF1

366

O14829
PPCSFGKQFGGKRGC

RAPGEF6

91

Q8TEU7
GFCAPGCTCPPGLFL

SSPOP

2921

A2VEC9
PPPAARLCCLGGGCG

SERTAD4-AS1

86

Q5TG53
CLPCGPGGKGRCFGP

OXT

41

P01178
PGGKGRCFGPNICCA

OXT

46

P01178
VGGFLCKCPPGFLGT

SVEP1

1326

Q4LDE5
CAVGVGCCFGTPLGG

CLCN1

271

P35523
PGKTFCCGICGRGFG

ZNF865

546

P0CJ78
RPFGCPVGGCGKKFT

ZXDC

236

Q2QGD7
GPGCTKECPGCLHGG

TIE1

221

P35590
CLPCGPGGKGRCFGP

AVP

41

P01185
PGGKGRCFGPSICCA

AVP

46

P01185
GCGCVCEPGWKGPNC

TNC

171

P24821
GGGSWKGRPFPCGAC

ZNF696

116

Q9H7X3
CKGFFGPDCTQCPGG

STAB1

721

Q9NY15
CPGFFGTLCEPCPGG

STAB1

1321

Q9NY15
GTLCEPCPGGLGGVC

STAB1

1326

Q9NY15
GGLCVTPGFCICPPG

WIF1

221

Q9Y5W5
PGVKTVGGGCCPCPC

SOCS7

71

O14512
GQPGSGGVCSCCGRL

TMC6

191

Q7Z403