Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

ATP6V1A ABCA1 MYO1C ABCA13 ACSS1 RSF1 ABCA7 DHX9 UBA7 KIF19 ABCC2 DYNC1H1 ACSS3 DNAH3 DHX57 BTAF1 MSH3 FANCM HELQ CCT6A MSH6 DNAH12 SMC3 MACF1 DHX32 KIF13A

8.05e-1061420326GO:0140657
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ATP6V1A NUGGC ABCA1 GBP6 ABCA13 MTG2 RSF1 GBP1 GBP2 ABCA7 DHX9 GBP4 GBP5 KIF19 ABCC2 DYNC1H1 DNAH3 DHX57 BTAF1 FANCM HELQ CCT6A DNAH12 SMC3 MACF1 DHX32 KIF13A

2.38e-0877520327GO:0017111
GeneOntologyMolecularFunctionATP hydrolysis activity

ATP6V1A ABCA1 ABCA13 RSF1 ABCA7 DHX9 KIF19 ABCC2 DYNC1H1 DNAH3 DHX57 BTAF1 FANCM HELQ CCT6A DNAH12 SMC3 MACF1 DHX32 KIF13A

2.67e-0844120320GO:0016887
GeneOntologyMolecularFunctionpyrophosphatase activity

ATP6V1A NUGGC ABCA1 GBP6 ABCA13 MTG2 RSF1 GBP1 GBP2 ABCA7 DHX9 GBP4 GBP5 KIF19 ABCC2 DYNC1H1 DNAH3 DHX57 BTAF1 FANCM HELQ CCT6A DNAH12 SMC3 MACF1 DHX32 KIF13A

1.20e-0783920327GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ATP6V1A NUGGC ABCA1 GBP6 ABCA13 MTG2 RSF1 GBP1 GBP2 ABCA7 DHX9 GBP4 GBP5 KIF19 ABCC2 DYNC1H1 DNAH3 DHX57 BTAF1 FANCM HELQ CCT6A DNAH12 SMC3 MACF1 DHX32 KIF13A

1.23e-0784020327GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ATP6V1A NUGGC ABCA1 GBP6 ABCA13 MTG2 RSF1 GBP1 GBP2 ABCA7 DHX9 GBP4 GBP5 KIF19 ABCC2 DYNC1H1 DNAH3 DHX57 BTAF1 FANCM HELQ CCT6A DNAH12 SMC3 MACF1 DHX32 KIF13A

1.23e-0784020327GO:0016818
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO1C KIF19 DYNC1H1 DNAH3 DNAH12 SMC3 KIF13A MYO16

2.80e-051182038GO:0003774
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF19 DYNC1H1 DNAH3 DNAH12 SMC3 KIF13A

7.83e-05702036GO:0003777
GeneOntologyMolecularFunctionapolipoprotein A-I receptor activity

ABCA1 ABCA7

1.03e-0422032GO:0034188
GeneOntologyMolecularFunctioncalcium ion binding

TTYH1 ADGRV1 ADGRE2 RYR3 FAT2 SYT11 PLA2G4F HSPG2 PCDHGA7 PCDHGA4 PPEF2 PPEF1 GRM7 THBS2 CDH22 LRP2 MACF1 UNC13C PCDH1

2.41e-0474920319GO:0005509
GeneOntologyMolecularFunctionapolipoprotein receptor activity

ABCA1 ABCA7

3.06e-0432032GO:0030226
GeneOntologyMolecularFunctionsingle guanine insertion binding

MSH3 MSH6

3.06e-0432032GO:0032142
GeneOntologyMolecularFunctionsingle-stranded 3'-5' DNA helicase activity

DHX9 HELQ

3.06e-0432032GO:1990518
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

RSF1 DHX9 BTAF1 MSH3 FANCM HELQ MSH6

3.23e-041272037GO:0008094
GeneOntologyMolecularFunctionligase activity

ATP6V1A ACSS1 GART UBA7 ACSS3 FPGS LARS1 PARS2

4.17e-041742038GO:0016874
GeneOntologyMolecularFunction3'-5' DNA helicase activity

DHX9 FANCM HELQ

5.26e-04162033GO:0043138
GeneOntologyMolecularFunctionpropionate-CoA ligase activity

ACSS1 ACSS3

6.09e-0442032GO:0050218
GeneOntologyMolecularFunctionshort-chain fatty acid-CoA ligase activity

ACSS1 ACSS3

6.09e-0442032GO:0031955
GeneOntologyMolecularFunctionadenylate cyclase inhibitor activity

ADGRV1 GRM7

6.09e-0442032GO:0010855
GeneOntologyMolecularFunctionguanine/thymine mispair binding

MSH3 MSH6

6.09e-0442032GO:0032137
GeneOntologyMolecularFunctionsingle base insertion or deletion binding

MSH3 MSH6

6.09e-0442032GO:0032138
GeneOntologyMolecularFunctionacetate-CoA ligase activity

ACSS1 ACSS3

6.09e-0442032GO:0003987
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DYNC1H1 DNAH3 DNAH12

7.55e-04182033GO:0008569
GeneOntologyMolecularFunctioncyclase inhibitor activity

ADGRV1 GRM7

1.01e-0352032GO:0010852
GeneOntologyMolecularFunctionDNA insertion or deletion binding

MSH3 MSH6

1.50e-0362032GO:0032135
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA1 ABCA13 ABCA7 ABCC2

1.54e-03492034GO:0140359
GeneOntologyMolecularFunctioncytoskeletal protein binding

MYO1C GBP1 GBP2 ADGRV1 ADD2 ADD3 EML5 SYT11 ANKRD2 KIF19 ANTXR1 MAP4K4 AGBL1 KLC3 KPTN SMC3 MACF1 ARHGEF2 KIF13A MYO16 MTSS2 MYBPC3

1.89e-03109920322GO:0008092
GeneOntologyBiologicalProcesspositive regulation of pyroptotic inflammatory response

GBP1 GBP2 GBP4 GBP5

1.13e-0692044GO:0140639
GeneOntologyBiologicalProcesscytolysis in another organism

GBP1 GBP2 GBP4 GBP5

1.13e-0692044GO:0051715
GeneOntologyBiologicalProcesspositive regulation of AIM2 inflammasome complex assembly

GBP1 GBP2 GBP5

3.79e-0642043GO:0140973
GeneOntologyBiologicalProcesscytolysis

GBP1 GBP2 GBP4 GBP5

4.32e-06122044GO:0019835
GeneOntologyBiologicalProcessregulation of AIM2 inflammasome complex assembly

GBP1 GBP2 GBP5

1.87e-0562043GO:0140971
GeneOntologyBiologicalProcessadhesion of symbiont to host

GBP6 GBP1 GBP2 GBP4

3.98e-05202044GO:0044406
GeneOntologyBiologicalProcesscellular response to interferon-beta

GBP6 GBP1 GBP2 GBP4 NDUFA13

5.06e-05412045GO:0035458
GeneOntologyBiologicalProcessAIM2 inflammasome complex assembly

GBP1 GBP2 GBP5

5.15e-0582043GO:0140970
GeneOntologyBiologicalProcesspyroptotic inflammatory response

GBP1 GBP2 DHX9 GBP4 GBP5

5.69e-05422045GO:0070269
GeneOntologyBiologicalProcessresponse to interferon-beta

GBP6 GBP1 GBP2 GBP4 NDUFA13

1.09e-04482045GO:0035456
GeneOntologyCellularComponenthost intracellular region

GBP6 GBP1 GBP2 GBP4

1.41e-0762084GO:0043656
GeneOntologyCellularComponenthost cell cytoplasm

GBP6 GBP1 GBP2 GBP4

1.41e-0762084GO:0030430
GeneOntologyCellularComponenthost cell part

GBP6 GBP1 GBP2 GBP4

1.41e-0762084GO:0033643
GeneOntologyCellularComponenthost intracellular part

GBP6 GBP1 GBP2 GBP4

1.41e-0762084GO:0033646
GeneOntologyCellularComponenthost cell cytoplasm part

GBP6 GBP1 GBP2 GBP4

1.41e-0762084GO:0033655
GeneOntologyCellularComponentsymbiont-containing vacuole

GBP6 GBP1 GBP2 GBP4

1.41e-0762084GO:0020003
GeneOntologyCellularComponentsymbiont-containing vacuole membrane

GBP6 GBP1 GBP2 GBP4

1.41e-0762084GO:0020005
GeneOntologyCellularComponentleading edge membrane

MYO1C ADGRV1 ADGRE2 ABCA7 SLC12A5 ANTXR1 PLA2G4F CSPG4 MACF1 ARHGEF2 SPATA13 MTSS2

1.37e-0621020812GO:0031256
GeneOntologyCellularComponentcell projection membrane

TTYH1 MYO1C PKD1L1 ADGRV1 ADGRE2 ABCA7 SLC12A5 ANTXR1 PLA2G4F ABCC2 CSPG4 LRP2 MACF1 ARHGEF2 SPATA13 MTSS2

7.08e-0643120816GO:0031253
GeneOntologyCellularComponenthost cellular component

GBP6 GBP1 GBP2 GBP4

1.19e-05152084GO:0018995
GeneOntologyCellularComponentruffle membrane

MYO1C ADGRE2 ABCA7 PLA2G4F MACF1 ARHGEF2 SPATA13 MTSS2

1.26e-051082088GO:0032587
GeneOntologyCellularComponentsymbiont cell surface

GBP1 GBP2 GBP5

5.24e-0582083GO:0106139
GeneOntologyCellularComponentother organism part

GBP1 GBP2 GBP5

7.80e-0592083GO:0044217
GeneOntologyCellularComponentruffle

MYO1C ADGRE2 ABCA7 PLA2G4F CSPG4 MACF1 ARHGEF2 SPATA13 MTSS2

2.29e-042062089GO:0001726
GeneOntologyCellularComponentasymmetric synapse

TNIK ADD2 ADD3 SORT1 SYT11 KALRN CNKSR2 GRIN2D GRM7 SLC8A3 AKAP9 MACF1 GRIP2 ARHGEF2

3.18e-0447720814GO:0032279
GeneOntologyCellularComponentactin-based cell projection

TTYH1 ATP6V1A MYO1C ADGRV1 ANTXR1 DYNC1H1 PKHD1L1 KPTN NPTXR SPATA13

4.92e-0427820810GO:0098858
GeneOntologyCellularComponentneuron to neuron synapse

TNIK ADD2 ADD3 SORT1 SYT11 KALRN CNKSR2 GRIN2D GRM7 SLC8A3 AKAP9 MACF1 GRIP2 ARHGEF2

7.89e-0452320814GO:0098984
GeneOntologyCellularComponentstereocilium membrane

MYO1C ADGRV1

1.44e-0362082GO:0060171
GeneOntologyCellularComponentcell leading edge

MYO1C ADGRV1 ADGRE2 ABCA7 SLC12A5 ANTXR1 PLA2G4F KPTN CSPG4 MACF1 ARHGEF2 SPATA13 MTSS2

1.57e-0350020813GO:0031252
GeneOntologyCellularComponentpostsynaptic specialization

TNIK ADD2 ADD3 SLC12A5 SYT11 KALRN CNKSR2 GRIN2D SLC8A3 AKAP9 MACF1 GRIP2 ARHGEF2

1.65e-0350320813GO:0099572
GeneOntologyCellularComponentpostsynaptic density

TNIK ADD2 ADD3 SYT11 KALRN CNKSR2 GRIN2D SLC8A3 AKAP9 MACF1 GRIP2 ARHGEF2

1.95e-0345120812GO:0014069
GeneOntologyCellularComponentmitotic cohesin complex

STAG1 SMC3

2.00e-0372082GO:0030892
DomainGBP_C

GBP6 GBP1 GBP2 GBP4 GBP5

3.84e-08102075PF02841
DomainG_GB1_RHD3_dom

GBP6 GBP1 GBP2 GBP4 GBP5

6.97e-08112075IPR030386
DomainGuanylate-bd_N

GBP6 GBP1 GBP2 GBP4 GBP5

6.97e-08112075IPR015894
DomainGuanylate-bd_C

GBP6 GBP1 GBP2 GBP4 GBP5

6.97e-08112075IPR003191
DomainGBP

GBP6 GBP1 GBP2 GBP4 GBP5

6.97e-08112075PF02263
DomainG_GB1_RHD3

GBP6 GBP1 GBP2 GBP4 GBP5

6.97e-08112075PS51715
DomainP-loop_NTPase

ATP6V1A NUGGC ABCA1 GBP6 MYO1C ABCA13 MTG2 GBP1 GBP2 ABCA7 DHX9 GBP4 GBP5 KIF19 ABCC2 DYNC1H1 DNAH3 DHX57 BTAF1 MSH3 FANCM HELQ MSH6 DNAH12 SMC3 DHX32 KIF13A MYO16

2.37e-0784820728IPR027417
Domain-

ATP6V1A NUGGC ABCA1 GBP6 ABCA13 MTG2 GBP1 GBP2 ABCA7 DHX9 GBP4 GBP5 ABCC2 DYNC1H1 DNAH3 DHX57 BTAF1 MSH3 FANCM HELQ MSH6 DNAH12 SMC3 DHX32

2.91e-06746207243.40.50.300
DomainTF_AP2

TFAP2E TFAP2A TFAP2C

1.32e-0552073IPR004979
DomainTF_AP2_C

TFAP2E TFAP2A TFAP2C

1.32e-0552073IPR013854
DomainTF_AP-2

TFAP2E TFAP2A TFAP2C

1.32e-0552073PF03299
DomainCalx_beta

ADGRV1 FREM1 SLC8A3

1.07e-0492073IPR003644
DomainCalx-beta

ADGRV1 FREM1 SLC8A3

1.07e-0492073PF03160
DomainDUF3657

FAM135A FAM135B

1.22e-0422072IPR022122
DomainDUF676

FAM135A FAM135B

1.22e-0422072PF05057
DomainCNKSR2

CNKSR2 CNKSR3

1.22e-0422072IPR010599
DomainDNA_mismatch_repair_MutS_N

MSH3 MSH6

1.22e-0422072IPR016151
DomainDUF3657

FAM135A FAM135B

1.22e-0422072PF12394
DomainDUF676_lipase-like

FAM135A FAM135B

1.22e-0422072IPR007751
Domain-

MSH3 MSH6

1.22e-04220723.40.1170.10
DomainDUF1170

CNKSR2 CNKSR3

1.22e-0422072PF06663
DomainSer/Thr-Pase_EF-hand_contain

PPEF2 PPEF1

1.22e-0422072IPR012008
DomainABC_A

ABCA1 ABCA13 ABCA7

2.74e-04122073IPR026082
DomainQuinoprotein_ADH-like_supfam

FAM234A EML5 WDR72 SEMA6C WDR36

2.97e-04532075IPR011047
DomainCRIC

CNKSR2 CNKSR3

3.64e-0432072PS51290
DomainCRIC_domain

CNKSR2 CNKSR3

3.64e-0432072IPR017874
DomainCRIC_ras_sig

CNKSR2 CNKSR3

3.64e-0432072PF10534
DomainDNA_mismatch_repair_MutS-lik_N

MSH3 MSH6

3.64e-0432072IPR007695
DomainMutS_I

MSH3 MSH6

3.64e-0432072PF01624
DomainARM-type_fold

STAG1 USP9X RYR3 XPO6 ANKAR ULK4 GCN1 AGBL1 USP24 RICTOR BTAF1 UPF2

4.18e-0433920712IPR016024
DomainDynein_heavy_chain_D4_dom

DYNC1H1 DNAH3 DNAH12

4.46e-04142073IPR024317
DomainDynein_heavy_dom-2

DYNC1H1 DNAH3 DNAH12

4.46e-04142073IPR013602
DomainDHC_N2

DYNC1H1 DNAH3 DNAH12

4.46e-04142073PF08393
DomainATPase_dyneun-rel_AAA

DYNC1H1 DNAH3 DNAH12

4.46e-04142073IPR011704
DomainAAA_8

DYNC1H1 DNAH3 DNAH12

4.46e-04142073PF12780
DomainAAA_5

DYNC1H1 DNAH3 DNAH12

4.46e-04142073PF07728
DomainDHC_fam

DYNC1H1 DNAH3 DNAH12

5.53e-04152073IPR026983
DomainDynein_heavy

DYNC1H1 DNAH3 DNAH12

5.53e-04152073PF03028
DomainDynein_heavy_dom

DYNC1H1 DNAH3 DNAH12

5.53e-04152073IPR004273
Domain-

ADGRV1 FAT2 HSPG2 THBS2 NPTXR CSPG4

6.60e-049520762.60.120.200
DomainACAS_N

ACSS1 ACSS3

7.23e-0442072PF16177
DomainACAS_N

ACSS1 ACSS3

7.23e-0442072IPR032387
DomainPPP5

PPEF2 PPEF1

7.23e-0442072PF08321
DomainSHR-BD

VPS13A VPS13B

7.23e-0442072IPR009543
DomainG8_domain

PKHD1 PKHD1L1

7.23e-0442072IPR019316
DomainG8

PKHD1 PKHD1L1

7.23e-0442072PS51484
DomainDNA_mmatch_repair_MutS_con_dom

MSH3 MSH6

7.23e-0442072IPR007860
DomainPPP_dom

PPEF2 PPEF1

7.23e-0442072IPR013235
DomainAldolase_II

ADD2 ADD3

7.23e-0442072SM01007
DomainG8

PKHD1 PKHD1L1

7.23e-0442072SM01225
DomainMutS_II

MSH3 MSH6

7.23e-0442072PF05188
DomainAldolase_II/adducin_N

ADD2 ADD3

7.23e-0442072IPR001303
DomainAldolase_II

ADD2 ADD3

7.23e-0442072PF00596
DomainG8

PKHD1 PKHD1L1

7.23e-0442072PF10162
DomainVPS13_C

VPS13A VPS13B

7.23e-0442072PF16909
DomainVPS13_C

VPS13A VPS13B

7.23e-0442072IPR031645
Domain-

ADD2 ADD3

7.23e-04420723.40.225.10
DomainSHR-BD

VPS13A VPS13B

7.23e-0442072PF06650
DomainConA-like_dom

ADGRV1 RYR3 FAT2 HSPG2 TRIM7 THBS2 NPTXR CSPG4 NEURL4

7.74e-042192079IPR013320
DomainDUF1605

DHX9 DHX57 DHX32

8.14e-04172073IPR011709
DomainAcyl_Trfase/lysoPLipase

FASN PLA2G4F PNPLA7

8.14e-04172073IPR016035
DomainOB_NTP_bind

DHX9 DHX57 DHX32

8.14e-04172073PF07717
DomainHA2

DHX9 DHX57 DHX32

9.68e-04182073SM00847
DomainHA2

DHX9 DHX57 DHX32

9.68e-04182073PF04408
DomainHelicase-assoc_dom

DHX9 DHX57 DHX32

9.68e-04182073IPR007502
DomainAAA

ABCA1 ABCA13 ABCA7 ABCC2 DYNC1H1 DNAH3 DNAH12

1.13e-031442077SM00382
DomainAAA+_ATPase

ABCA1 ABCA13 ABCA7 ABCC2 DYNC1H1 DNAH3 DNAH12

1.13e-031442077IPR003593
DomainMUTSd

MSH3 MSH6

1.20e-0352072SM00533
DomainMUTSac

MSH3 MSH6

1.20e-0352072SM00534
DomainMutS_V

MSH3 MSH6

1.20e-0352072PF00488
DomainDNA_mismatch_repair_MutS_clamp

MSH3 MSH6

1.20e-0352072IPR007861
DomainDNA_MISMATCH_REPAIR_2

MSH3 MSH6

1.20e-0352072PS00486
DomainAutophagy-rel_C

VPS13A VPS13B

1.20e-0352072IPR015412
DomainWHIM1_dom

RSF1 BAZ1A

1.20e-0352072IPR028942
DomainATG_C

VPS13A VPS13B

1.20e-0352072PF09333
DomainMutS_IV

MSH3 MSH6

1.20e-0352072PF05190
DomainMutS_III

MSH3 MSH6

1.20e-0352072PF05192
DomainDNA_mismatch_repair_MutS_C

MSH3 MSH6

1.20e-0352072IPR000432
DomainWHIM1

RSF1 BAZ1A

1.20e-0352072PF15612
DomainDNA_mismatch_repair_MutS_core

MSH3 MSH6

1.20e-0352072IPR007696
DomainHELICASE_CTER

DHX9 DHX57 BTAF1 FANCM HELQ DHX32

1.35e-031092076PS51194
DomainHELICASE_ATP_BIND_1

DHX9 DHX57 BTAF1 FANCM HELQ DHX32

1.35e-031092076PS51192
DomainHelicase_ATP-bd

DHX9 DHX57 BTAF1 FANCM HELQ DHX32

1.42e-031102076IPR014001
DomainDDT

RSF1 BAZ1A

1.78e-0362072PS50827
DomainPbH1

PKHD1 PKHD1L1

1.78e-0362072SM00710
DomainPbH1

PKHD1 PKHD1L1

1.78e-0362072IPR006626
DomainABC_tran

ABCA1 ABCA13 ABCA7 ABCC2

1.95e-03482074PF00005
DomainABC_TRANSPORTER_2

ABCA1 ABCA13 ABCA7 ABCC2

1.95e-03482074PS50893
DomainSpectrin

KALRN CCDC141 MACF1

2.02e-03232073PF00435
DomainCadherin

FREM1 FAT2 PCDHGA7 PCDHGA4 CDH22 PCDH1

2.03e-031182076IPR002126
DomainABC_TRANSPORTER_1

ABCA1 ABCA13 ABCA7 ABCC2

2.10e-03492074PS00211
DomainABC_transporter-like

ABCA1 ABCA13 ABCA7 ABCC2

2.27e-03502074IPR003439
DomainSAM

EPHB3 LRSAM1 PPFIA4 CNKSR2 CNKSR3

2.97e-03882075SM00454
DomainARM-like

STAG1 USP9X XPO6 ANKAR ULK4 GCN1 AGBL1 RICTOR BTAF1

3.25e-032702079IPR011989
DomainChorein_N

VPS13A VPS13B

3.28e-0382072PF12624
DomainPectin_lyase_fold/virulence

PKHD1 PKHD1L1

3.28e-0382072IPR011050
DomainCalx_beta

ADGRV1 SLC8A3

3.28e-0382072SM00237
DomainVPS13_N

VPS13A VPS13B

3.28e-0382072IPR026854
DomainLAMININ_IVA

HSPG2 LAMC2

3.28e-0382072PS51115
DomainLaminin_B

HSPG2 LAMC2

3.28e-0382072PF00052
Pubmed

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.

GBP6 GBP1 GBP2 GBP4 GBP5

4.02e-108208516689661
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

USP9X UNC5B GART ADD2 DHX9 FASN BOD1L1 MAP4K4 GCN1 FAM135A DYNC1H1 NOP56 USP24 LARS1 ISOC1 RICTOR ANKRD50 CCT6A SMC3 FANCI MACF1

2.13e-097082082139231216
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

STAG1 PFKP RXRB DHX9 FASN XPO6 GCN1 DYNC1H1 USP24 ELP1 BTAF1 CCT6A MSH6 NSUN5 SMC3 FANCI MACF1 ARHGEF2 MAP2K3

2.76e-095822081920467437
Pubmed

Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.

GBP6 GBP1 GBP2 GBP4 GBP5

3.27e-0911208518025219
Pubmed

Murine GBP-5, a new member of the murine guanylate-binding protein family, is coordinately regulated with other GBPs in vivo and in vitro.

GBP6 GBP1 GBP2 GBP5

6.19e-095208412396730
Pubmed

Unique features of different members of the human guanylate-binding protein family.

GBP1 GBP2 GBP4 GBP5

6.19e-095208417266443
Pubmed

Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.

GBP1 GBP2 GBP4 GBP5

6.19e-095208421151871
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYO1C LRSAM1 GART RSF1 PFKP BIRC6 DHX9 FASN GCN1 DYNC1H1 WDR36 NOP56 LARS1 ELP1 ISOC1 DHX57 RICTOR MSH3 CCT6A MSH6 NSUN5 UPF2 SMC3 BAZ1A FANCI MACF1 ARHGEF2 MAP2K3

1.18e-0813532082829467282
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

TNIK STAG1 LYPLA2 GMPR2 PFKP BIRC6 DHX9 FASN GCN1 DYNC1H1 NOP56 LARS1 ELP1 MSH3 CCT6A MSH6 NSUN5 UPF2 SMC3

5.72e-087042081929955894
Pubmed

A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection.

GBP6 GBP1 GBP2 GBP4 GBP5

7.92e-0819208521551061
Pubmed

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.

GBP1 GBP2 GBP4 GBP5

1.53e-079208424739961
Pubmed

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.

GBP1 GBP2 GBP4 GBP5

3.97e-0711208424715728
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

MYO1C DHX9 FASN GCN1 DHX57 RICTOR BTAF1 MSH6 ARHGEF2 NEURL4

4.33e-072022081033005030
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYO1C STAG1 RSF1 PFKP SLC30A2 FASN VPS13A PKHD1 ANTXR1 BOD1L1 ABCC2 NOP56 PCDHGA7 PCDHGA4 PPFIA4 DHX57 SKI DHRS7B CCT6A BAZ1A CSPG4 CNKSR3 MACF1 ARHGEF2 CFAP46 SPATA13

5.86e-0714422082635575683
Pubmed

Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling.

GBP1 GBP2 GBP4 GBP5

5.93e-0712208435906252
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

GART PFKP DHX9 MAP4K4 GCN1 DYNC1H1 HSPG2 NOP56 ELP1 DHX57 RICTOR NDUFA13 CCT6A MSH6 MACF1 ARHGEF2

7.94e-076012081633658012
Pubmed

Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of Brucella abortus infection.

GBP1 GBP2 GBP5

8.40e-074208338404575
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

USP9X PFKP FASN BOD1L1 GCN1 DYNC1H1 LARS1 MSH3 CCT6A MSH6 SMC3 BAZ1A

8.77e-073322081232786267
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

MYO1C MTG2 PFKP SORT1 VPS13A FPGS ELP1 RICTOR PARS2 DHRS7B MSH6 NSUN5 FANCI CNKSR3 DHX32 MAP2K3

8.84e-076062081636538041
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SPHK2 MTG2 BIRC6 ABCA7 FASN XPO6 ULK4 GCN1 DYNC1H1 ANKRD16 SEMA6C HSPG2 KALRN BTAF1 GRIN2D TXNRD2 TRIM7 FANCI CSPG4 ARHGEF2 SPATA13 HR

9.30e-0711052082235748872
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

TNIK ATP6V1A PFKP ADD2 ADD3 SLC12A5 DHX9 FASN MAP4K4 DYNC1H1 BMP2K NDUFA13 SLC6A11 CCT6A EHHADH ARHGEF2

1.21e-066212081622794259
Pubmed

The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.

PFKP FASN GCN1 DYNC1H1 LARS1 ELP1 DHX57 MSH6 SMC3 EHHADH

1.85e-062372081029564676
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ATP6V1A MYO1C GART PFKP DHX9 FASN GCN1 DYNC1H1 NOP56 LARS1 ISOC1 RICTOR NDUFA13 CCT6A MSH6 AKAP9 MACF1 MYO16

2.01e-068072081830575818
Pubmed

Analysis of transcription factor AP-2 expression and function during mouse preimplantation development.

TFAP2E TFAP2A TFAP2C

2.09e-065208316672719
Pubmed

The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.

PKHD1 PKHD1L1 LRP2

2.09e-065208320048263
Pubmed

AP-2α and AP-2β regulate dorsal interneuron specification in the spinal cord.

TFAP2E TFAP2A TFAP2C

2.09e-065208327984181
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYO1C USP9X GART RSF1 PFKP BIRC6 FASN GCN1 DYNC1H1 WDR36 USP24 ELP1 DHX57 MSH6 FANCI MACF1

2.32e-066532081622586326
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

ATP6V1A USP9X LRSAM1 GART GBP1 GBP2 SCRN1 GMPR2 PFKP POLA2 BIRC6 DHX9 FASN CLNS1A GCN1 DYNC1H1 USP24 LARS1 ELP1 ISOC1 CCT6A MSH6 FANCI MACF1 KIF13A

2.32e-0614552082522863883
Pubmed

Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.

MYO1C PFKP DHX9 FASN DYNC1H1 WDR36 NOP56 DHX57

2.68e-06144208835681168
Pubmed

Interactome of the Autoimmune Risk Protein ANKRD55.

USP9X DHX9 FASN GCN1 DYNC1H1 NOP56 LARS1 SMC3 FANCI

3.19e-06197208931620119
Pubmed

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.

MYO1C GART PFKP DHX9 FASN GCN1 DYNC1H1 LARS1 RICTOR CCT6A ARHGEF2

3.20e-063122081137120454
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

TNIK ATP6V1A ARRDC1 USP9X BOD1L1 MAP4K4 GCN1 WDR36 FANCI ARHGEF2 NEURL4

3.30e-063132081138270169
Pubmed

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

TNIK ABCA1 SORT1 EXOC3L1 LAMC2

3.56e-0639208521347282
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

FREM1 LAMC2 CSPG4 GRIP2

3.56e-0618208414730302
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

TNIK ATP6V1A MYO1C GART SCRN1 PFKP POLA2 BIRC6 DHX9 FASN CLNS1A ANTXR1 BOD1L1 DYNC1H1 NOP56 USP24 LARS1 CCT6A NSUN5 SMC3 BAZ1A LAMTOR3 MACF1

3.63e-0612972082333545068
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

ATP6V1A USP9X GART PFKP DHX9 FASN MAP4K4 GCN1 DYNC1H1 WDR36 NOP56 LARS1 ELP1 BTAF1 CCT6A SMC3 BAZ1A MACF1 ARHGEF2 NEURL4

3.97e-0610242082024711643
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

ADGRV1 FREM1 FAT2 EML5 AKAP9 EHHADH FANCI MACF1

4.01e-06152208834299191
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

MYO1C ABCA13 SYTL2 CEP95 VPS13A PKHD1 BOD1L1 HELQ LRP2

4.97e-06208208933230847
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ATP6V1A MYO1C USP9X SCRN1 PFKP HDHD2 ADD2 ADD3 SLC12A5 DHX9 FASN DYNC1H1 KALRN PPFIA4 LARS1 ELP1 DHX57 CNKSR2 NDUFA13 CCT6A UPF2 MACF1 ARHGEF2 PCDH1

5.65e-0614312082437142655
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

USP9X ADD3 FASN NFKBIE BOD1L1 MAP4K4 GCN1 DYNC1H1 NOP56 USP24 TFAP2A DHRS7B CCT6A MSH6

6.44e-065492081438280479
Pubmed

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.

GBP6 GBP1 GBP2 GBP4

6.87e-0621208419158679
Pubmed

Cloning and characterization of the mouse AP-2 epsilon gene: a novel family member expressed in the developing olfactory bulb.

TFAP2E TFAP2A TFAP2C

7.25e-067208314572467
Pubmed

Arf4 is required for Mammalian development but dispensable for ciliary assembly.

PKHD1 PKHD1L1 LRP2

7.25e-067208324586199
Pubmed

AP-2ε Expression in Developing Retina: Contributing to the Molecular Diversity of Amacrine Cells.

TFAP2E TFAP2A TFAP2C

7.25e-067208329467543
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

FAM234A BIRC6 ADD2 ADD3 SORT1 XPO6 ABCC2 MAP4K4 FAM135A WDR72 RICTOR CNKSR2 BTAF1 CNKSR3 MACF1 KIF13A

7.80e-067192081635337019
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

ATP6V1A USP9X GART ADD3 DHX9 FASN GCN1 DYNC1H1 NOP56 USP24 LARS1 ELP1 CCT6A SMC3 FANCI

7.91e-066382081533239621
Pubmed

LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.

PFKP DHX9 FASN GCN1 CCT6A SMC3

8.23e-0679208626446488
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

FASN GCN1 ELP1 RICTOR BTAF1 MSH6 FANCI

8.31e-06120208727320910
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

TNIK UNC5B LRSAM1 MTMR10 ADD2 ADD3 ABCC2 MAP4K4 FAM135A RICTOR CSPG4 MPZL2 PCDH1 VPS13B

9.63e-065692081430639242
Pubmed

MCM9 Is Required for Mammalian DNA Mismatch Repair.

PFKP NOP56 MSH3 MSH6

1.01e-0523208426300262
Pubmed

Proteomic data on the nuclear interactome of human MCM9.

PFKP NOP56 MSH3 MSH6

1.01e-0523208426870752
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

TNIK MYO1C STAG1 USP9X DHX9 BOD1L1 GCN1 NOP56 USP24 LARS1 MSH6 SMC3 MACF1

1.08e-054982081336634849
Pubmed

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.

PFKP FASN GCN1 DYNC1H1 CCT6A MSH6 FANCI

1.09e-05125208721654808
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

TNIK MYO1C USP9X ADGRV1 ADD2 ADD3 SYT11 BMP2K ELP1 DHRS7B MACF1 MTSS2

1.23e-054302081232581705
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

ATP6V1A MYO1C ARRDC1 LYPLA2 TM7SF3 ADGRV1 HDHD2 FASN EML5 FAM151A PKHD1 DYNC1H1 HSPG2 DPYS KALRN CNKSR2 CCT6A LRP2 LAMTOR3

1.29e-0510162081919056867
Pubmed

TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.

USP9X GART DHX9 FASN LARS1 ELP1 MSH6 SMC3

1.33e-05179208836261009
Pubmed

Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.

GBP6 GBP1 GBP2 GBP5

1.42e-0525208435139355
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

ATP6V1A MYO1C USP9X PFKP BOD1L1 MAP4K4 DYNC1H1 DNAH3 NOP56 LARS1 CCT6A MSH6 NSUN5 UPF2 SMC3 MACF1 MAP2K3

1.53e-058472081735235311
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

ATP6V1A FAM234A USP9X PFKP SORT1 FASN XPO6 GCN1 DYNC1H1 USP24 LARS1 ELP1 BTAF1 DHRS7B NDUFA13 SMC3 FANCI ARHGEF2

1.65e-059422081831073040
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

TNIK ATP6V1A KIZ PKD1L1 CEP95 NFKBIE MAP4K4 DYNC1H1 BMP2K FPGS WDR83 KLHL22 CCT6A CNKSR3 LRP2 ARHGEF2 NEURL4

1.68e-058532081728718761
Pubmed

Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins.

GBP1 GBP2 GBP5

1.72e-059208333479228
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

STAG1 RXRB SORT1 ZBTB37 FASN UBA7 DYNC1H1 LARS1 BTAF1 MSH3 SKI TFAP2A PARS2 SMC3 BAZ1A ARHGEF2 MAP2K3

1.78e-058572081725609649
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MYO1C USP9X BIRC6 MTMR10 ADD2 SORT1 CLNS1A VPS13A GCN1 ELP1 RICTOR PPEF2 PPEF1 TFAP2A MSH6 AKAP9 FANCI ARHGEF2 NEURL4

2.00e-0510492081927880917
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

ATP6V1A MYO1C BIRC6 ADD3 DHX9 VPS13A GCN1 FAM135A DYNC1H1 WDR36 BMP2K RICTOR CNKSR2 ANKRD50 PKHD1L1 CCT6A

2.02e-057772081635844135
Pubmed

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly.

PFKP DHX9 FASN DYNC1H1 HSPG2 CCT6A

2.10e-0593208638245532
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

RSF1 POLA2 BIRC6 BOD1L1 GCN1 WDR36 NOP56 CCDC141 TFAP2C CCT6A BAZ1A FANCI

2.88e-054692081227634302
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

CYP1B1 MYO1C USP9X GART PFKP DHX9 SORT1 XPO6 GCN1 DYNC1H1 KLC3 NOP56 LARS1 DHX57 CNKSR2 KPTN MSH6 SMC3 FANCI ARHGEF2 NEURL4

3.24e-0512842082117353931
Pubmed

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.

GBP1 GBP2 GBP5

3.36e-0511208327693356
Pubmed

The mouse adducin gene family: alternative splicing and chromosomal localization.

ADD2 ADD3 ABCC2

3.36e-0511208310602987
Pubmed

The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins.

RSF1 BAZ1A FANCI

3.36e-0511208324800743
Pubmed

Immunohistochemical expression patterns of AP2alpha and AP2gamma in the developing fetal human breast.

TFAP2A TFAP2C

3.56e-052208218042070
Pubmed

Identification and characterization of a new gene family induced during macrophage activation.

GBP6 GBP2

3.56e-05220821753106
Pubmed

Genetic Regulation of Guanylate-Binding Proteins 2b and 5 during Leishmaniasis in Mice.

GBP2 GBP5

3.56e-052208229467757
Pubmed

Dimerization and its role in GMP formation by human guanylate binding proteins.

GBP1 GBP2

3.56e-052208220923658
Pubmed

Homo and hetero dimerisation of the human guanylate-binding proteins hGBP-1 and hGBP-5 characterised by affinities and kinetics.

GBP1 GBP5

3.56e-052208229618166
Pubmed

Expression of adducin genes during erythropoiesis: a novel erythroid promoter for ADD2.

ADD2 ADD3

3.56e-052208215963851
Pubmed

Perlecan and basement membrane-chondroitin sulfate proteoglycan (bamacan) are two basement membrane chondroitin/dermatan sulfate proteoglycans in the Engelbreth-Holm-Swarm tumor matrix.

HSPG2 SMC3

3.56e-05220828621634
Pubmed

Preferential incorporation of shorter and less unsaturated acyl phospholipids into high density lipoprotein-like particles in the ABCA1- and ABCA7-mediated biogenesis with apoA-I.

ABCA1 ABCA7

3.56e-052208225665932
Pubmed

Msh3 is a limiting factor in the formation of intergenerational CTG expansions in DM1 transgenic mice.

MSH3 MSH6

3.56e-052208216552576
Pubmed

Targeted deletion of the gamma-adducin gene (Add3) in mice reveals differences in alpha-adducin interactions in erythroid and nonerythroid cells.

ADD2 ADD3

3.56e-052208219425068
Pubmed

FGF21 increases cholesterol efflux by upregulating ABCA1 through the ERK1/2-PPARγ-LXRα pathway in THP1 macrophage-derived foam cells.

ABCA1 FGF21

3.56e-052208224735204
Pubmed

Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARγ activation to decrease diet-induced obesity.

FASN DHRS7B

3.56e-052208222863804
Pubmed

Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification.

MSH3 MSH6

3.56e-052208215238604
Pubmed

A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination.

MSH3 MSH6

3.56e-052208215238605
Pubmed

Activator protein-2 impairs the invasion of a human extravillous trophoblast cell line.

TFAP2A TFAP2C

3.56e-052208219443578
Pubmed

AP-2.2, a novel gene related to AP-2, is expressed in the forebrain, limbs and face during mouse embryogenesis.

TFAP2A TFAP2C

3.56e-05220828808408
Pubmed

Normal light response, photoreceptor integrity, and rhodopsin dephosphorylation in mice lacking both protein phosphatases with EF hands (PPEF-1 and PPEF-2).

PPEF2 PPEF1

3.56e-052208211713293
Pubmed

The biological characteristics of transcription factors AP-2α and AP-2γ and their importance in various types of cancers.

TFAP2A TFAP2C

3.56e-052208230824562
Pubmed

Cell surface chondroitin sulphate proteoglycan 4 (CSPG4) binds to the basement membrane heparan sulphate proteoglycan, perlecan, and is involved in cell adhesion.

HSPG2 CSPG4

3.56e-052208229462330
Pubmed

Autophagy restricts Chlamydia trachomatis growth in human macrophages via IFNG-inducible guanylate binding proteins.

GBP1 GBP2

3.56e-052208223086406
Pubmed

Serous tubal intraepithelial carcinoma upregulates markers associated with high-grade serous carcinomas including Rsf-1 (HBXAP), cyclin E and fatty acid synthase.

RSF1 FASN

3.56e-052208220228782
Pubmed

AP-2alpha and AP-2gamma regulate tumor progression via specific genetic programs.

TFAP2A TFAP2C

3.56e-052208218443366
Pubmed

Commensal Escherichia coli reduces epithelial apoptosis through IFN-alphaA-mediated induction of guanylate binding protein-1 in human and murine models of developing intestine.

GBP1 GBP2

3.56e-052208220483731
Pubmed

Functional genomics of AP-2α and AP-2γ in cancers: in silico study.

TFAP2A TFAP2C

3.56e-052208233213447
Pubmed

Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.

GBP2 GBP5

3.56e-052208233876762
Pubmed

The human guanylate-binding proteins hGBP-1 and hGBP-5 cycle between monomers and dimers only.

GBP1 GBP5

3.56e-052208228580591
Pubmed

Identification and characterization of a conserved family of protein serine/threonine phosphatases homologous to Drosophila retinal degeneration C.

PPEF2 PPEF1

3.56e-05220829326663
Pubmed

Interference with activator protein-2 transcription factors leads to induction of apoptosis and an increase in chemo- and radiation-sensitivity in breast cancer cells.

TFAP2A TFAP2C

3.56e-052208220459791
Pubmed

ATP-binding cassette transporter 1 (ABCA1) deficiency decreases platelet reactivity and reduces thromboxane A2 production independently of hematopoietic ABCA1.

ABCA1 ABCA7

3.56e-052208226749169
Pubmed

The mismatch repair protein Msh6 influences the in vivo AID targeting to the Ig locus.

MSH3 MSH6

3.56e-052208216618598
InteractionKCNA3 interactions

MYO1C ABCA13 USP9X UNC5B GART SYTL2 ADD2 DHX9 FASN CEP95 VPS13A PKHD1 BOD1L1 MAP4K4 GCN1 FAM135A DYNC1H1 NOP56 USP24 LARS1 ISOC1 RICTOR ANKRD50 HELQ CCT6A SMC3 FANCI LRP2 MACF1

2.11e-0887120629int:KCNA3
Cytoband1p22.2

GBP6 GBP1 GBP2 GBP4 GBP5

1.68e-072820951p22.2
CytobandEnsembl 112 genes in cytogenetic band chr1p22

GBP6 GBP1 GBP2 GBP4 GBP5 CLCA4

4.15e-051372096chr1p22
Cytoband1q21-q22

DUSP12 NPR1 ARHGEF2

1.54e-042320931q21-q22
GeneFamilyBlood group antigens|CD molecules|Proteoglycans

HSPG2 SMC3 CSPG4

1.49e-0571383570
GeneFamilyATP binding cassette subfamily A

ABCA1 ABCA13 ABCA7

1.49e-04141383805
GeneFamilyDEAH-box helicases

DHX9 DHX57 DHX32

2.27e-04161383500
GeneFamilySterile alpha motif domain containing

EPHB3 LRSAM1 PPFIA4 CNKSR2 CNKSR3

5.68e-04881385760
GeneFamilyMTOR complex 1|MTOR complex 2

PRR5 RICTOR

5.70e-04513821333
GeneFamilyMutS homologs|PWWP domain containing

MSH3 MSH6

5.70e-04513821026
GeneFamilyCohesin complex

STAG1 SMC3

1.57e-03813821060
GeneFamilyAnkyrin repeat domain containing

ANKRD2 ANKAR NFKBIE ANKRD16 ANKRD50 SOWAHA MYO16

2.59e-032421387403
GeneFamilyX-linked mental retardation|RNA helicases

FANCM HELQ

3.04e-031113821168
GeneFamilyKelch like|BTB domain containing

KLHL40 KLHL22 KLHL11

4.02e-03421383617
GeneFamilyProtein phosphatase catalytic subunits|EF-hand domain containing

PPEF2 PPEF1

4.27e-03131382693
CoexpressionHOWARD_B_CELL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

GBP1 GBP2 GBP4 GBP5

3.56e-06142074M41166
CoexpressionLI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN

SCRN1 PFKP ADD2 MAP4K4 GCN1 BTAF1 MSH6 BAZ1A FANCI

6.61e-061642079M13108
CoexpressionBENPORATH_SUZ12_TARGETS

EPHB3 TTYH1 CYP1B1 CRLF1 TFAP2E UNC5B ACSS1 OTOP3 DNAJC22 SLC30A2 RYR3 SLC12A5 EML5 CYP26C1 MGAT5B ZMYND15 GRIN2D GRM7 TFAP2C SLC6A11 SLC8A3 APCDD1L LRP2

8.25e-06103520723M9898
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MID_MESOTHELIAL_CELL

FAM234A MYO1C ARRDC1 USP9X UNC5B TM7SF3 PSMB9 DNAJC22 METTL21A XPO6 VPS13A HSPG2 NPR1 PRR5 LAMC2 ANKRD50 GRM7 PKHD1L1 NSUN5 FRY KIF13A

2.43e-0595520721M45680
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

TTYH1 ATP6V1A MTG2 SCRN1 ADGRV1 SORT1 SYT11 MGAT5B KALRN HELQ ZNF3 FANCI CARF KIF13A SPATA13

1.40e-0541920415Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K1
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#2

TTYH1 ADGRV1 SYT11 MAP4K4 MGAT5B RTL1 LRP2 SPATA13

2.39e-051222048Facebase_RNAseq_e8.5_Floor Plate_1000_K2
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#4

TTYH1 ADGRV1 SYT11 MGAT5B RTL1 LRP2 SPATA13

2.59e-05902047Facebase_RNAseq_e8.5_Floor Plate_500_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

EPHB3 TTYH1 ABCA1 ACSS1 SCRN1 ADGRV1 SYT11 MGAT5B SEMA6C FANCM RTL1 NPTXR SPATA13

2.60e-0533920413Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000

EPHB3 TTYH1 ABCA1 ARRDC1 ACSS1 PSMB9 SCRN1 ADGRV1 SORT1 EML5 SYT11 MGAT5B SEMA6C FANCM TMTC1 AKAP9 SMC3 BAZ1A RTL1 NPTXR LRP2 MACF1 DHX32 SPATA13

2.81e-0598620424Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000
CoexpressionAtlaskidney_adult_GlomCapSys_Tie2_k-means-cluster#2_top-relative-expression-ranked_100

GBP6 PSMB9

9.19e-0522042gudmap_kidney_adult_GlomCapSys_Tie2_k2_100
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 ADGRV1 FREM1 RYR3 PKHD1 KALRN CNKSR2 PKHD1L1 LRP2 UNC13C MYO16

1.19e-09184208112cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 ADGRV1 FREM1 RYR3 PKHD1 KALRN CNKSR2 PKHD1L1 LRP2 UNC13C MYO16

1.19e-09184208112b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 ADGRV1 FREM1 RYR3 PKHD1 KALRN CNKSR2 PKHD1L1 LRP2 UNC13C MYO16

1.19e-0918420811ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

USP9X RSF1 ADGRV1 BIRC6 DYNC1H1 MSH3 ANKRD50 KLHL11 AKAP9 VPS13B

2.69e-0819320810abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK SYTL2 ZBTB37 VPS13A USP24 RICTOR BTAF1 AKAP9 MACF1 VPS13B

3.59e-0819920810f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA13 GBP1 ADGRV1 ANKAR PKHD1 ABCC2 TDRD5 PKHD1L1 SLC6A11

7.44e-081622089bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellwk_15-18-Epithelial-Proximal_epithelial-SMG_basal_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TM7SF3 KLC3 TFAP2A TFAP2C TRIM7 CSPG4 APCDD1L MPZL2 HR

1.51e-071762089045b12c90f7dd49a9778dadcdf8f18125b380531
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP6 STAG1 PSMB9 GBP2 GBP4 GBP5 CCT6A AKAP9 SMC3

1.66e-07178208901dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

TNIK VPS13A ABCC2 WDR72 DPYS BMP2K EHHADH CNKSR3 LRP2

2.53e-071872089d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

SYTL2 RYR3 SORT1 ANTXR1 KALRN FRY MACF1 UNC13C KIF13A

2.77e-0718920896b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK SYTL2 ZBTB37 VPS13A USP24 BTAF1 AKAP9 MACF1 VPS13B

3.30e-0719320899337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellChildren_(3_yrs)-Immune-mast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TNIK SYTL2 ADGRE2 RYR3 UBA7 BMP2K PRR5 SLC8A3

5.75e-071512088bbf735c6433c3fc2feedb24ed6f48c51d545fb60
ToppCelldroplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHX9 UBA7 EML5 NFKBIE PLA2G4F ZMYND15 BMP2K MTSS2

1.82e-06176208824b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCA13 PKHD1 ABCC2 WDR72 DPYS EHHADH CNKSR3 LRP2

2.44e-0618320886878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

TNIK SLC30A2 PKHD1 ABCC2 WDR72 DPYS EHHADH LRP2

2.86e-061872088738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

SYTL2 RYR3 SORT1 KALRN FRY MACF1 UNC13C KIF13A

2.98e-06188208834e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellCOVID-19-kidney-CD-PC|COVID-19 / Disease (COVID-19 only), tissue and cell type

KIZ SYTL2 PFKP FREM1 PKHD1 WDR72 TFAP2A APCDD1L

2.98e-0618820888f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell(2)_Fibroblasts-(22)_Fibro-3|World / Cell class and subclass of bone marrow stroma cells in homeostatis

TTYH1 CRLF1 FREM1 ADD3 FGF21 TMEM200C CNKSR2 THBS2

3.22e-0619020883aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRLF1 FASN PLA2G4F TDRD5 LAMC2 CCDC141 LRP2 MPZL2

3.22e-061902088aaf5f1c1ff7b1454f4e5dacfeb48e1c3627e3372
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRLF1 FASN PLA2G4F TDRD5 LAMC2 CCDC141 LRP2 MPZL2

3.22e-061902088a20123d5c6cb8c2f0dfd99bbfdb571a73c36234d
ToppCellrenal_papilla_nuclei-Adult_normal_reference|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 KIZ TM7SF3 SORT1 ACSS3 TMTC1 FRY UNC13C

3.48e-0619220886c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

CYP26C1 WDR72 SEMA6C PRR5 GRM7 FRY CSPG4 MTSS2

3.48e-061922088e16035b3328f9b1b2e28d234c62ba88387540550
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

ABCA1 PSMB9 GBP1 GBP2 GBP4 GBP5 NFKBIE EXOC3L1

3.90e-0619520881992a1673b7213e25f3c76ac77da35c57daceddd
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_4|COVID-19_Severe / Disease condition and Cell class

ABCA1 PSMB9 GBP1 GBP2 GBP4 GBP5 NFKBIE EXOC3L1

3.90e-061952088787ea9f38ad8e2a836222ca97f4d927f7e79517d
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 USP9X FAM151A VPS13A BOD1L1 DYNC1H1 AKAP9 MACF1

3.90e-0619520887796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 USP9X FAM151A VPS13A BOD1L1 DYNC1H1 AKAP9 MACF1

3.90e-0619520883e519cffa6144a62b06124642a14c9ff39b76554
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTYH1 DHDH EXOC3L1 HERC3 CDH22 SOWAHA MTSS2

3.96e-0613820876b83c434895d82eaf3c222eef27acec76f9c0a77
ToppCellStriatum-Neuronal-Excitatory|Striatum / BrainAtlas - Mouse McCarroll V32

ADD2 KALRN CNKSR2 GRM7 FAM135B SOWAHA AKAP9 UPF2

4.05e-06196208867400193ba469cf4d939e94f5ed94995e384bc07
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK SYTL2 ZBTB37 VPS13A USP24 BTAF1 AKAP9 MACF1

4.21e-06197208857ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TNIK ADGRV1 FASN PLA2G4F AGBL1 ACSS3 CCDC141 LRP2

4.37e-0619820882e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellBAL-Severe|BAL / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CYP1B1 PSMB9 GBP1 GBP2 GBP4 GBP5 BAZ1A MACF1

4.37e-061982088454aee3f4fe6d0beeccc55200b4495f4f9b44feb
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

SYTL2 ADD3 GBP4 GBP5 SYT11 USP24 TIGIT MACF1

4.70e-0620020882281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellPND03-Immune-Immune_Myeloid-DC-maDC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PSMB9 GBP2 GBP5 PLA2G4F ZMYND15 BMP2K TRIM7

8.87e-061562087095281ea78aefa0ee638191a03f8d6f62a86a9ff
ToppCellPND03-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PSMB9 GBP2 GBP5 PLA2G4F ZMYND15 BMP2K TRIM7

8.87e-06156208729b04143f71a0ecc600ac670abd1d521bee55fe7
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUGGC CRLF1 ADD2 KIF19 PKHD1L1 SOWAHA MYBPC3

1.09e-05161208760f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 SYTL2 KIF19 DNAH3 GRM7 DNAH12 CFAP46

1.49e-05169208714aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 ADGRV1 RYR3 PKHD1 PKHD1L1 LRP2 UNC13C

1.49e-05169208712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK ADGRE2 BMP2K CCDC141 SLC8A3 APCDD1L MYO16

1.61e-051712087ac37c80c832504986c7a201d84f4b6aff5e5f323
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK ADGRE2 BMP2K CCDC141 SLC8A3 APCDD1L MYO16

1.61e-051712087b6502a81df4f25660f3ae4b7443a1d999df2d32b
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

EPHB3 ABCA1 FAM234A ABCA7 GRIN2D MAP2K3 BBS12

1.67e-051722087f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DUSP12 UBA7 CYP26C1 KLC3 ELP1 THBS2 BBS12

1.80e-05174208732fdeeebeeeca657eac6329caad4c28ca54e4d1c
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DUSP12 UBA7 CYP26C1 KLC3 ELP1 THBS2 BBS12

1.80e-051742087eb8012823b08729b462d1e5212f4873bb6b4eb1e
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

ATP6V1A GBP6 FAT2 FAM135A CLCA4 BAZ1A MPZL2

1.87e-0517520870cc215109d9915af47e4d0a120ce2e46910715fa
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCG ADGRV1 FREM1 FAM151A PKHD1 WDR72 LRP2

1.87e-051752087887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5B GBP4 EXOC3L1 MGAT5B NPR1 CLCA4 TMTC1

1.94e-051762087dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK GBP6 TTC39C SYTL2 GBP4 SYT11 TIGIT

2.01e-0517720876d86b2f97426b552dff5ce6ddf0ead1285ed618e
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK GBP6 TTC39C SYTL2 GBP4 SYT11 TIGIT

2.01e-051772087d8b1bbc224d062a57a6ad40b4b2af5d6e0fe63b3
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 USP9X EML5 FAM151A ULK4 FAM135A RTL1

2.09e-051782087fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC30A2 ABCC2 WDR72 DPYS PRR5 EHHADH LRP2

2.24e-0518020871363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

ADGRV1 FASN PLA2G4F AGBL1 ACSS3 CCDC141 LRP2

2.24e-051802087198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 ABCC2 WDR72 DPYS EHHADH CNKSR3 LRP2

2.24e-051802087864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK SYTL2 DHX9 VPS13A BOD1L1 CCT6A MACF1

2.41e-051822087e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

UNC5B WDR72 PCDHGA7 ITGA10 TFAP2A SLC8A3 GRIP2

2.41e-051822087ba066ff9029cc052b76e2330ec168cb2e9b7e498
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYTL2 MGAT5B CNKSR2 GRM7 CDH22 UNC13C CFAP46

2.41e-05182208714a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK SYTL2 DHX9 VPS13A BOD1L1 CCT6A MACF1

2.41e-0518220871710eab3037a87609d21838be2d2d29c3bc36651
ToppCellHippocampus-Neuronal-Inhibitory|Hippocampus / BrainAtlas - Mouse McCarroll V32

PIP5KL1 SEMA6C GRIN2D ANKRD50 GRIP2 MYO16 MTSS2

2.41e-051822087b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

TNIK ABCA13 VPS13A PKHD1 DPYS CNKSR3 LRP2

2.58e-05184208751ed1ebfdef45149541917c66cbacad87072e51f
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|metastatic_Brain / Location, Cell class and cell subclass

SYT11 HSPG2 NPR1 ITGA10 TMTC1 FRY EHHADH

2.67e-051852087ad52970e88e8947ef256095bd4b40229b912d58a
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC30A2 PKHD1 ABCC2 WDR72 DPYS EHHADH LRP2

2.67e-0518520871bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PSMB9 GBP1 GBP2 GBP4 GBP5 PKHD1 BAZ1A

2.67e-051852087f30fb9d75cdb757b206312992aaf7485bc900f96
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC30A2 ABCC2 WDR72 DPYS PRR5 EHHADH LRP2

2.77e-0518620878287146f0ba415ea04475588117d4668ae00f75c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYTL2 MGAT5B KALRN CNKSR2 GRM7 CDH22 UNC13C

2.77e-051862087bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

TNIK STAG1 BIRC6 ADD3 BOD1L1 UPF2 VPS13B

2.77e-05186208703db813598b67b1e08f759758a1c2023396921fa
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC30A2 ABCC2 WDR72 DPYS PRR5 EHHADH LRP2

2.86e-05187208771eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYTL2 MGAT5B KALRN CNKSR2 GRM7 CDH22 UNC13C

2.86e-051872087f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGRV1 PKHD1 PLA2G4F AGBL1 ACSS3 CCDC141 ARHGEF2

2.86e-0518720875df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TM7SF3 PKHD1 ABCC2 WDR72 DPYS EHHADH LRP2

2.86e-051872087dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TM7SF3 PKHD1 ABCC2 WDR72 DPYS EHHADH LRP2

2.86e-051872087f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIZ MTMR10 FREM1 FRY APCDD1L UNC13C MYO16

2.86e-051872087f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|343B / Donor, Lineage, Cell class and subclass (all cells)

GBP4 EXOC3L1 KALRN PCDHGA7 ITGA10 FRY PCDH1

2.96e-051882087fe7143c36e4a883745862d3c3147cf751b440e46
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Striatum / BrainAtlas - Mouse McCarroll V32

ADD2 CNKSR2 GRM7 FAM135B SOWAHA AKAP9 UPF2

2.96e-051882087e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CRLF1 ADGRV1 VPS13A PKHD1 FRY LRP2 MPZL2

2.96e-051882087beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP9X BIRC6 DYNC1H1 USP24 RICTOR BTAF1 MACF1

2.96e-051882087ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellIPF-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

TNIK FASN PLA2G4F AGBL1 NPR1 CCDC141 LRP2

2.96e-0518820875f5fad2773e421760e67dbace23fd1f847a2e1e0
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|343B / Donor, Lineage, Cell class and subclass (all cells)

GBP4 EXOC3L1 KALRN PCDHGA7 ITGA10 FRY PCDH1

2.96e-051882087cbf32b675a7cd0c808d5c9c22dfa7fa79fbe2437
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNIK ADGRE2 SLC30A2 BMP2K FAM135B SLC8A3 MYO16

3.06e-051892087aba941ba6ce7702418b3f470bde573d123c4aade
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYTL2 MTMR10 FREM1 PKHD1 TFAP2A FRY APCDD1L

3.06e-0518920878ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CYP1B1 HSPG2 ITGA10 PKHD1L1 TMTC1 UNC13C MPZL2

3.06e-0518920877346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

TNIK PKHD1 ABCC2 WDR72 DPYS CNKSR3 LRP2

3.06e-0518920870be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYTL2 MTMR10 FREM1 PKHD1 TFAP2A FRY APCDD1L

3.17e-0519020874836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

ABCA13 RYR3 KIF19 DNAH3 LAMC2 DNAH12 CFAP46

3.28e-051912087ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK PKHD1 ABCC2 WDR72 DPYS FAM135B LRP2

3.28e-0519120871c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

TNIK ADGRV1 FASN PLA2G4F AGBL1 ACSS3 CCDC141

3.28e-051912087a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

CYP1B1 PSMB9 GBP1 GBP2 UBA7 GBP4 BAZ1A

3.28e-0519120872da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK PKHD1 ABCC2 WDR72 DPYS FAM135B LRP2

3.28e-0519120873c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellfacs-Skin|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRLF1 TFAP2E FAT2 KLC3 TFAP2A CSPG4 HR

3.28e-051912087ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

ABCA13 RYR3 KIF19 DNAH3 LAMC2 DNAH12 CFAP46

3.28e-0519120876228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

HSPG2 NPR1 ITGA10 ANKRD50 PKHD1L1 UNC13C MPZL2

3.39e-051922087c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNIK ADGRE2 SLC30A2 BMP2K FAM135B SLC8A3 MYO16

3.39e-051922087690cf19e9b0b2ada80097c63eae827529aa5b6f3
ToppCellfacs-Skin-Anagen-3m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PFKP ANTXR1 WDR36 TFAP2C BAZ1A MPZL2 MAP2K3

3.39e-051922087ec1fd2fb6e71f87189d66261909a84e2be63cacb
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

ADGRV1 FASN PLA2G4F AGBL1 ACSS3 CCDC141 LRP2

3.39e-05192208706013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNIK ADGRE2 SLC30A2 BMP2K FAM135B SLC8A3 MYO16

3.39e-0519220873d6c4c5847ca1e44fa380403d25af45d5b51ee9b
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNIK ADGRE2 SLC30A2 BMP2K FAM135B SLC8A3 MYO16

3.39e-051922087e0412964a3ee1bf3c0ef64f9a6f20f7e7835701e
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

ADGRV1 FASN PLA2G4F AGBL1 ACSS3 CCDC141 LRP2

3.39e-05192208758c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGRV1 PKHD1 PLA2G4F AGBL1 ACSS3 CCDC141 MPZL2

3.39e-051922087fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNIK ADGRE2 SLC30A2 BMP2K FAM135B SLC8A3 MYO16

3.39e-051922087b5871247a5f3e970fa05b33fff21bef9d2ab5741
ToppCellCOVID-19-kidney-CD-PC|kidney / Disease (COVID-19 only), tissue and cell type

KIZ SYTL2 PFKP FREM1 PKHD1 FRY APCDD1L

3.50e-051932087738689d009e4b118d7ce3171a207294b95cbe78b
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TNIK ADGRV1 FASN PLA2G4F ACSS3 CCDC141 LRP2

3.50e-051932087f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CRLF1 ADGRV1 PKHD1 TFAP2C FRY LRP2 MPZL2

3.50e-051932087b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCellMonocytes-Tissue-resident_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

UNC5B PRKD3 SYT11 ANTXR1 FAM135A BMP2K SKI

3.50e-051932087198552810dcac8d0ca63a78badd6702b49ff6edf
Drug3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; MCF7; HT_HG-U133A

TPMT CYP1B1 PRKD3 LAMC2 PPEF1 KLHL22 FRY ARHGEF2 ZMYM6 MTSS2 MYBPC3

2.01e-06197207113382_UP
Diseaseepilepsy (implicated_via_orthology)

TNIK SLC12A5 DHX9 MAP4K4 DYNC1H1 KALRN GRIN2D UNC13C

1.89e-051632048DOID:1826 (implicated_via_orthology)
DiseaseColorectal Carcinoma

CYP1B1 ABCA1 ABCA13 SLC12A5 VPS13A PKHD1 ABCC2 DNAH3 KALRN FPGS CNKSR2 MSH6 CDH22 AKAP9 LRP2 HR

3.34e-0570220416C0009402
Diseasesleep disorder (implicated_via_orthology)

TFAP2E TFAP2A TFAP2C

5.16e-05112043DOID:535 (implicated_via_orthology)
Diseasecystatin C measurement

KIZ ACSS1 ADGRV1 FGF21 PKHD1 WDR72 KALRN CSPG4 LRP2 PPTC7 MYBPC3

1.22e-0440220411EFO_0004617
Diseasespastic quadriplegic cerebral palsy 3 (implicated_via_orthology)

ADD2 ADD3

1.42e-0432042DOID:0081361 (implicated_via_orthology)
DiseaseCohen syndrome (implicated_via_orthology)

VPS13A VPS13B

1.42e-0432042DOID:0111590 (implicated_via_orthology)
DiseaseEndometrial cancer

MSH3 MSH6

2.83e-0442042cv:C0007103
DiseaseENDOMETRIAL CANCER

MSH3 MSH6

2.83e-0442042608089
DiseaseEndometrial carcinoma

MSH3 MSH6

2.83e-0442042cv:C0476089
Diseaseuric acid measurement

TNIK ABCA1 SYTL2 ADGRV1 POLA2 BIRC6 WDR72 DNAH3 RPS6KA4 ANKRD50 SKI LRP2 MPZL2

3.51e-0461020413EFO_0004761
Diseasecolorectal carcinoma (is_implicated_in)

ANTXR1 MSH3 MSH6

4.55e-04222043DOID:0080199 (is_implicated_in)
Diseaseurinary pH measurement

WDR72 KALRN

4.69e-0452042EFO_0010136
Diseaseserum selenium measurement

TTYH1 PKHD1 FAM135B KIF13A

4.98e-04532044EFO_0005266
Diseasepallidum volume

SYTL2 BIRC6 WDR72

6.69e-04252043EFO_0006933
DiseaseDepressive Symptoms

CYP1B1 FASN TXNRD2

7.53e-04262043C0086132
Diseaseintraocular pressure measurement

ABCA1 STAG1 PKHD1 ANTXR1 BOD1L1 KALRN ISOC1 TXNRD2 CSPG4 TANGO2 MYBPC3

8.89e-0450920411EFO_0004695
Diseasealopecia (is_implicated_in)

TPMT HR

9.76e-0472042DOID:987 (is_implicated_in)
Diseasesuicidal ideation

NUGGC WDR36 CFAP46

1.04e-03292043EFO_0004320
Diseaseage at menopause

BIRC6 BOD1L1 DYNC1H1 FANCM HELQ TFAP2C MSH6 FANCI

1.26e-033022048EFO_0004704
Diseasecerebellar ataxia (implicated_via_orthology)

VPS13A PNPLA7

1.30e-0382042DOID:0050753 (implicated_via_orthology)
Diseasexerostomia

ANTXR1 WDR72

1.30e-0382042EFO_0009869
Diseasechildhood trauma measurement, alcohol consumption measurement

HERC3 PCDHGA7 PCDHGA4 CNKSR2

1.50e-03712044EFO_0007878, EFO_0007979
Diseasemean corpuscular hemoglobin concentration

DUSP12 FAM234A LRSAM1 GMPR2 ABCA7 VPS13A ANTXR1 MAF1 BMP2K KALRN SKI BAZ1A MACF1 DHX32 MAP2K3 MYO16 VPS13B

1.83e-03110520417EFO_0004528
Diseaseresponse to serotonin-norephinephrine reuptake inhibitor

GBP6 BIRC6 GBP5

1.97e-03362043EFO_0006325
Diseasecerebral palsy (implicated_via_orthology)

ADD2 ADD3

2.06e-03102042DOID:1969 (implicated_via_orthology)
Diseaseglucagon-like peptide-1 measurement

ULK4 AGBL1

2.06e-03102042EFO_0008465
DiseaseAlzheimer disease

ABCA1 MYO1C ABCA7 SORT1 PRKD3 PKHD1 ANTXR1 MAP4K4 MYO16 MTSS2

2.13e-0348520410MONDO_0004975
DiseaseSecondary Open Angle Glaucoma

WDR36 TXNRD2

3.00e-03122042C0271148
Diseaseautoimmune thyroiditis (is_implicated_in)

PSMB9 LRP2

3.00e-03122042DOID:7188 (is_implicated_in)
DiseaseGlaucoma, Open-Angle

WDR36 TXNRD2

3.00e-03122042C0017612
DiseaseAlzheimer disease, dementia

TFAP2A CFAP46

3.00e-03122042MONDO_0001627, MONDO_0004975
Diseasevolumetric bone mineral density

ACSS1 ADGRV1 SMC3

3.07e-03422043EFO_0007620
DiseaseObesity

CYP1B1 GCG FASN FGF21 BBS12 VPS13B

3.12e-032052046C0028754
DiseaseMalignant neoplasm of breast

CYP1B1 RXRB FASN EXOC3L1 BOD1L1 KALRN ELP1 GRIN2D HELQ TFAP2A MSH6 SLC8A3 AKAP9 MACF1 DHX32 VPS13B

3.39e-03107420416C0006142
Diseasered blood cell density measurement

FAM234A ADGRV1 PRKD3 ZBTB37 PKHD1 ANTXR1 ULK4 BMP2K KALRN RICTOR BAZ1A MPZL2 MYO16 VPS13B

3.40e-0388020414EFO_0007978
Diseasefructose measurement

TNIK ISOC1

3.53e-03132042EFO_0010477
DiseaseGlaucoma, Primary Open Angle

WDR36 TXNRD2

3.53e-03132042C0339573
Diseaseobsolete aging, epigenetic status

TPMT PKHD1 KIF13A

3.97e-03462043EFO_0000473, GO_0007568
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

ABCA1 LRP2

4.10e-03142042DOID:10976 (biomarker_via_orthology)
Diseaserostral middle frontal gyrus volume measurement

ARRDC1 AGBL1

4.10e-03142042EFO_0010328
Diseaseglaucoma

ABCA1 PKHD1 ANTXR1 KALRN TXNRD2

4.43e-031542045MONDO_0005041
DiseaseAlopecia, Male Pattern

ABCC2 HR

4.71e-03152042C4083212
DiseaseReplication Error Phenotype

MSH3 MSH6

4.71e-03152042C1721098
DiseaseProteinuria

LRP2 UNC13C

4.71e-03152042HP_0000093
DiseaseMicrosatellite Instability

MSH3 MSH6

4.71e-03152042C0920269
DiseaseAndrogenetic Alopecia

ABCC2 HR

4.71e-03152042C0162311
DiseaseFemale pattern alopecia (disorder)

ABCC2 HR

4.71e-03152042C0263477
Diseaseserum gamma-glutamyl transferase measurement

TNIK STAG1 SYT11 FGF21 CYP26C1 PKHD1 ABCC2 GCN1 ACSS3 KALRN SKI SOWAHA ARHGEF2 SPATA13

4.73e-0391420414EFO_0004532
Diseaseinflammatory biomarker measurement, YKL40 measurement

MSH6 FANCI MYO16

5.31e-03512043EFO_0004869, EFO_0004872
Diseaseattention deficit hyperactivity disorder, bipolar disorder, autism spectrum disorder, schizophrenia, major depressive disorder

KIZ SLC12A5 CNKSR2

5.31e-03512043EFO_0003756, EFO_0003888, MONDO_0002009, MONDO_0004985, MONDO_0005090
DiseaseDisease Exacerbation

ABCA13 ABCA7 RXRB NOP56 LAMC2

5.91e-031652045C0235874
Diseasehuman papilloma virus infection, oropharynx cancer

TFAP2A UNC13C MYO16

5.92e-03532043EFO_0001668, EFO_1001931
DiseaseSeizures, Focal

SLC12A5 ABCC2 DYNC1H1 SLC8A3

5.96e-031042044C0751495
DiseaseEye Abnormalities

FREM1 TFAP2A

6.04e-03172042C0015393
DiseaseBone marrow hypocellularity

FANCM FANCI

6.77e-03182042C1855710
Diseaseleft ventricular mass

CCDC141 MYBPC3

6.77e-03182042EFO_0009289
Diseasesusceptibility to childhood ear infection measurement

PSMB9 SEMA6C ELP1 SLC8A3 VPS13B

6.85e-031712045EFO_0007904

Protein segments in the cluster

PeptideGeneStartEntry
EVVGRLILGAHSVTA

SYT11

391

Q9BT88
VTELVGALSDILHVE

TDRD5

341

Q8NAT2
ETDTSLIRGLVLDHG

CCT6A

201

P40227
IDHLVLETVERLGEA

TTYH1

136

Q9H313
VSEDHVSALLGLRGD

EXOC3L1

676

Q86VI1
DLLVLTQEREEVSGH

FAM234A

226

Q9H0X4
DVINISGHRLGTAEI

ACSS1

551

Q9NUB1
TTAAVEETIGRHVLG

AKAP9

1741

Q99996
EETIGRHVLGILDRS

AKAP9

1746

Q99996
VAEEVLLGVHAATGL

COX18

66

Q8N8Q8
RESIRISGELIGNAH

C8orf86

176

Q6ZUL3
LLTSLVEGEAVHLAR

TFAP2C

301

Q92754
ELGVDVDVRATSTHL

ANKRD16

261

Q6P6B7
TASVIIALTDGELHE

ANTXR1

141

Q9H6X2
RLVLGVTDDGEGSHI

BIRC6

4186

Q9NR09
SVTRGARHGELELDI

CSPG4

471

Q6UVK1
SHLLDGLEDVLRGLS

ADGRE2

331

Q9UHX3
LRNHGVVALGETLEE

ADD3

291

Q9UEY8
HGIEEERQDLTTALG

ARHGEF2

406

Q92974
VSEARLVEDIGHELT

ABCA1

1191

O95477
GESVELHIIRSRGSL

ADGRV1

791

Q8WXG9
RGGTELVFEVTRAHV

APCDD1L

346

Q8NCL9
VTLLTSLVEGEAVHL

TFAP2A

286

P05549
AEATVHLLRSEGVEL

CFAP46

661

Q8IYW2
AEEEGRLHSVQGLLS

CFAP46

1841

Q8IYW2
EGQELEVIHTTLTGL

ABCA13

1051

Q86UQ4
GHASVVSLLIDRGAE

ANKRD50

726

Q9ULJ7
EIALRSGVFHVEGLD

NPR1

731

P16066
DIHERSIATDVLLGL

DHX32

186

Q7L7V1
VGRHQVTLEESLAEG

BMP2K

46

Q9NSY1
LLVLQTDSEIITGHG

BBS12

681

Q6ZW61
IHDVRTIAEVEGAGV

ARRDC1

216

Q8N5I2
ADVGHLVGTLGRVTE

ABCA7

391

Q8IZY2
EILRLHILASGADVT

BAZ1A

551

Q9NRL2
VLGDLLSVGTDRRIH

AGBL1

31

Q96MI9
LTSLVEGEAVHLARD

TFAP2E

296

Q6VUC0
VGHVTERLDGGTDIT

RBM23

336

Q86U06
LLTVHAIDLDEGVNG

PCDHGA7

261

Q9Y5G6
SGGVVRIAHVELADA

HSPG2

3536

P98160
VHRGVSRNEDLLEVG

NSUN5

111

Q96P11
DHITLSARGVTILVD

ANKAR

1206

Q7Z5J8
GLHTGEVRTARALLD

PCDHGA4

651

Q9Y5G9
SGELRHVEGTIILHI

FANCI

261

Q9NVI1
LVILDELGRGTSTHD

MSH3

971

P20585
LAGTAIHGLEERELD

OTOP3

391

Q7RTS5
IEIRSVETGHLDGVF

MAP4K4

1181

O95819
AVSEGVVHEDLRLLL

NOP56

66

O00567
LELVGRGVEVHIVAD

ISOC1

221

Q96CN7
EVLTQVHEGFELGTL

PIP5KL1

86

Q5T9C9
LTVETGDAHIIGRIE

MAF1

16

Q9H063
HLSVVLQEEEGRDLS

MTMR10

396

Q9NXD2
VGVSEAGLQHEILRR

LRSAM1

611

Q6UWE0
EVVSLILEHGGDLNI

MYO16

236

Q9Y6X6
LVDLSGTLHIEDAAV

HDHD2

11

Q9H0R4
LVGDALRELSIHSDI

HERC3

711

Q15034
LERVTTLEEQLAGAH

PPFIA4

176

O75335
TALHLAVETQERGLV

NFKBIE

406

O00221
VDEVLREGHINLSGL

KIAA1109

876

Q2LD37
LVEDGVVRALGHDLL

DPYS

26

Q14117
LVGGHEITSGLEVIS

FANCM

1821

Q8IYD8
EGTVHRILLGDVQTI

CARF

661

Q8N187
TFGLTLGHVVDEIQR

EHHADH

71

Q08426
DEGSVLLLHRALGDE

HR

931

O43593
ILVHIGFLTEESGDV

MGAT5B

286

Q3V5L5
LIGRAAHIAVLDSEI

FAM135A

1486

Q9P2D6
LTGELVVTGHLDRES

FAT2

871

Q9NYQ8
HVDLTGDGLQELAVV

KPTN

371

Q9Y664
GEITHLQGIIDDLVV

MTSS2

216

Q765P7
TIEIRGIGLVTHQDG

PCDH1

386

Q08174
GTDSALHRIIEVVDA

PFKP

186

Q01813
QTEAHLEIREDGTVG

FGF21

56

Q9NSA1
IGELYGLRTTEEALH

NDUFA13

121

Q9P0J0
NGLRTEHGVFEITLE

FREM1

1486

Q5H8C1
LLTSELGVTEHVEGD

KALRN

1526

O60229
LGALVTIDVHARDVV

DNAH12

1161

Q6ZR08
TDGLHEELEFIRILG

MACF1

2181

O94854
IHEGDLVEVVLSALA

PRKD3

131

O94806
TAEDLLRIGVTLAGH

EPHB3

961

P54753
FNDTLRLIGEHIDGV

KIR2DS3

66

Q14952
VDGVIGEIRLSVVHT

MPZL2

131

O60487
HILVLLDTEGLGDVE

GBP1

91

P32455
HTLVLLDTEGLGDIE

GBP2

91

P32456
HTLVLLDTEGLGDVE

GBP4

106

Q96PP9
HTLVLLDTEGLGDVE

GBP5

91

Q96PP8
HTLVLLDTEGLGDVE

GBP6

91

Q6ZN66
GTVLIGSEHGLIEVD

ELP1

31

O95163
VAIVEELGRRHADGS

GCG

136

P01275
VSHSLEAIELGLGEA

KLC3

71

Q6P597
DGVDIASIGLHDLRE

ABCC2

1361

Q92887
DTGHRIIIEDLLEAT

GCN1

2146

Q92616
VEHTIRDILGGIRST

GMPR2

301

Q9P2T1
TVHDGRIIVAAGVTD

KLHL40

506

Q2TBA0
AVELRITEANLTGHE

RPS6KA4

11

O75676
IGDIHGRSFRILVES

LRP2

406

P98164
VTITAAGVDHRVILG

PSMB9

196

P28065
SSGSEGEILTREHIE

KIZ

296

Q2M2Z5
AHSLVLVDELGRGTA

MSH6

1206

P52701
LGVRERSGHSVSLID

PLA2G4F

446

Q68DD2
LDVLQGRVAELEHGS

NPTXR

271

O95502
VSEHGVGILIESLIV

OOSP4A

81

A0A2R8YFL7
DDHISVRATILLGEL

RICTOR

416

Q6R327
GDLVGVVETLTHQAR

PNPLA7

641

Q6ZV29
ISVAELEEGATLIAH

KIF19

21

Q2TAC6
IVAALLGAHVTITDR

METTL21A

81

Q8WXB1
FLVVRGGEVVHRSDE

PPTC7

161

Q8NI37
SIEADEGLIIGTHSR

BOD1L1

1556

Q8NFC6
RTGQVEIVEHFLSLG

ANKRD2

256

Q9GZV1
HLTAEGQATLERLEG

CLNS1A

176

P54105
IRVSTGSVHEVLELA

KLHL11

166

Q9NVR0
SGILFDVVLVVEGRH

KLHL22

46

Q53GT1
SEGLSLAVLAVRHEE

CCDC141

381

Q6ZP82
LISSLADVHIEVGNR

BTAF1

781

O14981
TLGALTVIDVHARDV

DNAH3

1336

Q8TD57
VHRVAGEGALELVLE

DNLZ

136

Q5SXM8
GHVAGRELLTAVAEV

FAM151A

456

Q8WW52
RRLEGDTALQGVSHI

DHX57

651

Q6P158
ESTGEIIRLGDTAHT

CEP95

176

Q96GE4
VSGAENVRTILLGEH

CYP26C1

96

Q6V0L0
ERETAAVIFLHGLGD

LYPLA2

21

O95372
VEGLHAIVVSDRDGV

LAMTOR3

16

Q9UHA4
EAARLLVVVTDGESH

ITGA10

266

O75578
GRRHETGVDDTVTVL

DHDH

201

Q9UQ10
LERLEGVEGVAHIID

DYNC1H1

2241

Q14204
ILREAAAIHVLVTGS

FPGS

556

Q05932
HSIRIEGDVTLGGLF

GRM7

41

Q14831
LHLLETSIDGILADV

LAMC2

1156

Q13753
LEGHVLSEARELVAL

CYP1B1

166

Q16678
AGTIFLIDELTGDIH

CDH22

106

Q9UJ99
RLASVGIDDSHTVVL

EML5

786

Q05BV3
GGALEELIRELTASH

DHRS7B

86

Q6IAN0
LSDLLSRLVEVIGEH

FRY

1886

Q5TBA9
TLIGRAAHIAVLDSE

FAM135B

1376

Q49AJ0
TGRIDSLGLVVVDEL

HELQ

451

Q8TDG4
AERTGAIHVGDRILA

GRIP2

691

Q9C0E4
VIEGDHRTLLEGSGL

FASN

2476

P49327
VHVSRVGGLEDQLSV

CRLF1

241

O75462
VLGLSEGATNEEIHR

DNAJC22

281

Q8N4W6
DHLREAGITAVLTVD

DUSP12

46

Q9UNI6
TGHRGKDISTILDEE

RSF1

1056

Q96T23
RHEEGITVISDLLLG

PKD1L1

1441

Q8TDX9
EDLVVLVRGGASEHI

C8B

421

P07358
SLDELQEGDHIGLTR

NEURL4

426

Q96JN8
HGVVLSSRALRDGEV

NEURL4

551

Q96JN8
DTVGVVRREDGTLHF

NEURL4

636

Q96JN8
GIRGISHVIVDEIHE

DHX9

501

Q08211
LHGGVSDITDLELLD

PPEF2

291

O14830
VGIHVVDGVLEDIRL

UPF2

841

Q9HAU5
ELVRETTAGHLALLV

SLC12A5

816

Q9H2X9
IVDNEILVIHGGISE

PPEF1

276

O14829
LGEIAVSIVRALEHL

MAP2K3

166

P46734
GSLEVVDSSGEIIHR

KIF13A

851

Q9H1H9
LELRGTIVEESVNGH

RTL1

666

A6NKG5
GLIHGREVGEFSVLE

SYTL2

346

Q9HCH5
GEVLLDDRTHLTIGN

PARS2

406

Q7L3T8
RTGETGIEETILEGH

USP9X

1416

Q93008
TILDSGGIIVAIEHS

SORT1

526

Q99523
EISAILGGLEDHILR

NUGGC

636

Q68CJ6
ITLEGDQVSHRGALT

SMC3

651

Q9UQE7
RSHAIGVEEELESTG

TMEM200C

606

A6NKL6
LLVLQGVHESRGVTE

PRR5

181

P85299
IHLTENGIRVDIGDT

LARS1

1156

Q9P2J5
DHLGQEVIVLSALTG

MTG2

361

Q9H4K7
IELRAHAILVSDGGE

PKHD1

1981

P08F94
GHAGARDIVSIQELI

POLA2

86

Q14181
ELEHLRQALEGGLDT

SKI

541

P12755
ALDVIVSLLEEHGQG

SCRN1

126

Q12765
HRSIDVRDGILLATG

RXRB

386

P28702
VLRNHGVVALGDTVE

ADD2

286

P35612
VAGHRISAGAIEESI

ACSS3

561

Q9H6R3
IGELHSQLDGSEVLL

CLCA4

396

Q14CN2
LGVTRIGHQELVLEA

CNK3/IPCEF1

51

G9CGD6
GVSRIGHQELILEAV

CNKSR2

56

Q8WXI2
LGVTRIGHQELVLEA

CNKSR3

51

Q6P9H4
GLDILDRSSELIHSG

SPATA13

446

Q96N96
AIEIRSVETGHLDGV

TNIK

1301

Q9UKE5
GHLSRVRVALDLEVG

TRIM7

456

Q9C029
GRSDDEVRVLGAVHI

ZBTB37

231

Q5TC79
EISEDTRSHGVLLGR

ZNF3

101

P17036
IDSIFIVLEAGIGHR

VPS13A

1726

Q96RL7
IHTEAVAGIVGRADV

TMTC1

156

Q8IUR5
GIGISTDILTHDIRE

UNC13C

401

Q8NB66
HEEEGRELSGLVIIT

TMEM220

91

Q6QAJ8
IVTVSGDGLLHEVLN

SPHK2

241

Q9NRA0
GHEDAAVLLVVRLGA

SOWAHA

396

Q2M3V2
RSIHVREDGSLEIGD

UBA7

226

P41226
TVTVTLGDERGRVHE

RYR3

1366

Q15413
HELGEEAVLLRGTTV

ZNF75CP

141

Q92670
ALTTLEVVGRRLGVH

nan

86

A6NDN8
IETGTLERHETGERA

WDR72

586

Q3MJ13
VLAISDGIEHIGNLR

SLC6A11

211

P48066
IIGLELDTEGHRLFV

SEMA6C

491

Q9H3T2
VEAIRLVTLILHGSE

STAG1

391

Q8WVM7
ELVRVGHSELVGEII

ATP6V1A

41

P38606
GHSELVGEIIRLEGD

ATP6V1A

46

P38606
RIFLEVLESSVAEHG

TIGIT

121

Q495A1
DDNIIHFTVGEGIRI

PKHD1L1

3361

Q86WI1
HVTQEGLDEATGLRV

UNC5B

91

Q8IZJ1
VSDHEILAGSVDGRV

WDR83

161

Q9BRX9
HLERITEGDVVVGIA

GART

601

P22102
RVIGGSNHLAVVLDD

TMEM87B

341

Q96K49
TDITRIIFEHLEGLS

ZMYM6

1181

O95789
EILLSADHIIIATGG

TXNRD2

176

Q9NNW7
LHSEDIELGAVSALI

USP24

301

Q9UPU5
ALDVVLVRGSGQEHE

VPS13B

3871

Q7Z7G8
DGTRHVVSLEDVGLA

THBS2

131

P35442
ESILHEGSTGCRVVE

XPO6

876

Q96QU8
HIVAEGVSEESLNRL

TTC39C

201

Q8N584
DRGHSVVGVEISELG

TPMT

81

P51580
TDEHGTILGIDLLVD

ZMYND15

211

Q9H091
IILVDADGHVTFTER

TANGO2

241

Q6ICL3
DVVREFGIDLISGLH

ULK4

96

Q96C45
LLVVAVLASEHRVAG

TM7SF3

6

Q9NS93
FGDHIISVDTDGILI

WDR36

171

Q8NI36
VRDLLLSVEGVEALH

SLC30A2

241

Q9BRI3
VEDLLSIVASVLHLG

MYO1C

301

O00159
RTDKHRGIIIETEGD

SLC8A3

266

P57103
GLATEGTRHTLTVRE

MYBPC3

56

Q14896
LLSGLRVHGVVFEDD

GRIN2D

106

O15399