Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionexopeptidase activity

MMP14 MMP16 CTSC

1.48e-04110193GO:0008238
GeneOntologyMolecularFunctionmetalloaminopeptidase activity

MMP14 MMP16

2.75e-0426192GO:0070006
GeneOntologyMolecularFunctionaminopeptidase activity

MMP14 MMP16

7.57e-0443192GO:0004177
GeneOntologyMolecularFunctionmetalloexopeptidase activity

MMP14 MMP16

1.99e-0370192GO:0008235
GeneOntologyMolecularFunctionpeptidase activity

MMP14 MMP16 CTSC USP24

2.98e-03654194GO:0008233
HumanPhenoPremature loss of primary teeth

CTSC FERMT1

2.40e-042162HP:0006323
HumanPhenoOsteolytic defects of bones

MMP14 CTSC

2.89e-042362HP:0010737
HumanPhenoOsteolysis involving bones of the upper limbs

MMP14 CTSC

2.89e-042362HP:0045039
DomainDUF3377

MMP14 MMP16

5.26e-064182PF11857
DomainPept_M10A_metallopeptidase_C

MMP14 MMP16

5.26e-064182IPR021805
DomainPept_M10A_Zn_BS

MMP14 MMP16

9.14e-0515182IPR021158
DomainHemopexin_CS

MMP14 MMP16

1.18e-0417182IPR018486
DomainPept_M10A_stromelysin-type

MMP14 MMP16

1.33e-0418182IPR016293
DomainPeptidoglycan-bd-like

MMP14 MMP16

1.65e-0420182IPR002477
DomainPG_binding_1

MMP14 MMP16

1.65e-0420182PF01471
DomainHEMOPEXIN

MMP14 MMP16

2.19e-0423182PS00024
Domain-

MMP14 MMP16

2.19e-04231822.110.10.10
DomainHemopexin-like_dom

MMP14 MMP16

2.19e-0423182IPR000585
DomainHEMOPEXIN_2

MMP14 MMP16

2.19e-0423182PS51642
DomainHemopexin-like_repeat

MMP14 MMP16

2.19e-0423182IPR018487
DomainHemopexin

MMP14 MMP16

2.19e-0423182PF00045
DomainHX

MMP14 MMP16

2.19e-0423182SM00120
DomainPept_M10A

MMP14 MMP16

2.19e-0423182IPR021190
DomainM10A_MMP

MMP14 MMP16

2.19e-0423182IPR033739
DomainPeptidase_M10

MMP14 MMP16

2.39e-0424182PF00413
DomainZnMc

MMP14 MMP16

3.51e-0429182SM00235
DomainPeptidase_Metallo

MMP14 MMP16

3.51e-0429182IPR006026
DomainCYSTEINE_SWITCH

MMP14 MMP16

7.04e-0441182PS00546
DomainPept_M10_metallopeptidase

MMP14 MMP16

7.74e-0443182IPR001818
Domain-

MMP14 MMP16

2.72e-03811823.40.390.10
DomainMetalloPept_cat_dom

MMP14 MMP16

2.72e-0381182IPR024079
DomainZINC_PROTEASE

MMP14 MMP16

3.95e-0398182PS00142
PathwayREACTOME_TGFBR3_PTM_REGULATION

MMP14 MMP16

6.12e-0510172MM17232
PathwayREACTOME_TGFBR3_PTM_REGULATION

MMP14 MMP16

7.48e-0511172M48251
PathwayREACTOME_SIGNALING_BY_TGFBR3

MMP14 MMP16

2.84e-0421172MM17231
PathwayWP_MATRIX_METALLOPROTEINASES

MMP14 MMP16

5.45e-0429172MM15981
PathwayWP_MATRIX_METALLOPROTEINASES

MMP14 MMP16

5.84e-0430172M39652
PathwayREACTOME_CARGO_CONCENTRATION_IN_THE_ER

CTSC MIA2

7.07e-0433172M27591
PathwayREACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES

MMP14 MMP16

7.07e-0433172M26976
PathwayREACTOME_CARGO_CONCENTRATION_IN_THE_ER

CTSC MIA2

8.42e-0436172MM15300
PathwayREACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES

MMP14 MMP16

9.38e-0438172MM14611
PathwayWP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION

MMP14 MMP16

1.37e-0346172M46450
PathwayREACTOME_SIGNALING_BY_TGFBR3

MMP14 MMP16

1.56e-0349172M48250
Pubmed

Membrane-type MMPs enable extracellular matrix permissiveness and mesenchymal cell proliferation during embryogenesis.

MMP14 MMP16

2.83e-07219218022611
Pubmed

A cancer cell metalloprotease triad regulates the basement membrane transmigration program.

MMP14 MMP16

8.48e-07319216983145
Pubmed

Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization.

MMP14 MMP16

8.48e-0731929119382
Pubmed

Matrix metalloproteinase gene polymorphisms and bronchopulmonary dysplasia: identification of MMP16 as a new player in lung development.

MMP14 MMP16

8.48e-07319218784838
Pubmed

Changes in the expression of membrane type-matrix metalloproteinases genes (MMP14, MMP15, MMP16, MMP24) during treatment and their potential impact on the survival of patients with non-small cell lung cancer (NSCLC).

MMP14 MMP16

1.70e-06419235062057
Pubmed

Prion fragment peptides are digested with membrane type matrix metalloproteinases and acquire enzyme resistance through Cu²⁺-binding.

MMP14 MMP16

1.70e-06419224970228
Pubmed

Expression pattern of four membrane-type matrix metalloproteinases in the normal and diseased mouse mammary gland.

MMP14 MMP16

1.70e-06419215895410
Pubmed

mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human prostatic cell lines and their down-regulation in human malignant prostatic tissue.

MMP14 MMP16

2.82e-06519212661033
Pubmed

MT3-MMP Promotes Excitatory Synapse Formation by Promoting Nogo-66 Receptor Ectodomain Shedding.

MMP14 MMP16

2.82e-06519229196321
Pubmed

The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells.

MMP14 MMP16

4.24e-06619214645246
Pubmed

Membrane-type matrix metalloproteinases: Their functions and regulations.

MMP14 MMP16

5.93e-06719225794647
Pubmed

Secreted versus membrane-anchored collagenases: relative roles in fibroblast-dependent collagenolysis and invasion.

MMP14 MMP16

5.93e-06719219542530
Pubmed

Cleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinases.

MMP14 MMP16

5.93e-06719212879005
Pubmed

Structural differences of matrix metalloproteinases. Homology modeling and energy minimization of enzyme-substrate complexes.

MMP14 MMP16

1.55e-051119210949161
Pubmed

Membrane-type MMPs are indispensable for placental labyrinth formation and development.

MMP14 MMP16

2.56e-051419220858856
Pubmed

Matrix metalloproteinases in tumor invasion.

MMP14 MMP16

3.38e-051619210949577
Pubmed

Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor.

MMP14 MMP16

3.38e-051619237701782
Pubmed

Matrix metalloproteinases.

MMP14 MMP16

6.49e-052219210419448
Pubmed

Functional interactions between matrix metalloproteinases and glycosaminoglycans.

MMP14 MMP16

6.49e-052219223421805
Pubmed

Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.

AMFR USP24

6.49e-052219237225996
Pubmed

Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo.

MMP14 MMP16

7.75e-052419215734845
Pubmed

Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.

MMP14 MMP16

1.76e-043619220587546
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

AMFR CTSC SOAT1 ZNF551 MIA2

3.81e-04120319529180619
CytobandEnsembl 112 genes in cytogenetic band chr19q13

SLC7A9 ZNF551 SIGLEC7

1.24e-021192193chr19q13
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP14 MMP16

1.75e-0424152891
CoexpressionNABA_ECM_REGULATORS

MMP14 MMP16 CTSC CST9LP1

2.46e-05242194MM17062
ToppCelldroplet-Marrow-nan-3m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC SOAT1 MIA2

4.22e-05171183992df143d76f9e7fb1997a8996f61e941f0f9d4f
ToppCellImmune_cells-Monocytes|Immune_cells / Lineage and Cell class

CTSC SOAT1 MIA2

4.37e-051731833eced40a65453a023a1673658592e7e2a099119b
ToppCellfacs-GAT-Fat-3m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A9 FERMT1 MIA2

5.00e-0518118311cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCellfacs-GAT-Fat-3m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A9 FERMT1 MIA2

5.00e-051811835ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCellfacs-GAT-Fat-3m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A9 FERMT1 MIA2

5.00e-05181183e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCelldroplet-Marrow-nan-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC SOAT1 MIA2

5.08e-05182183bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MMP14 MMP16 FERMT1

5.16e-0518318327a57cd8ea924420e182f3d72f5b29b00dea8fa0
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP14 SOAT1 FERMT1

5.59e-05188183bfd3b4f57785596b2bd2c657e0d2d8b0f40ba36d
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

MMP14 MMP16 CTSC

5.68e-0518918346c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP14 MMP16 CTSC

6.05e-0519318368089ba4123e2f9bea9aae0023a844b5a57bfc0e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 CTSC MIA2

6.05e-05193183ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP14 CTSC SIGLEC7

6.24e-051951835a7c74f96f213c504abd65e751800da7e03e47d9
ToppCellNS-critical-LOC-Myeloid-Macrophage|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MMP14 SOAT1 SIGLEC7

6.43e-051971835fb0696376a5501b7c87e0f2f5e4fff3da2903f2
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MMP14 CTSC SOAT1

6.52e-051981833b4611c9ee4d42e042a29ddb4580a95938d87d65
ToppCelltumor_Lung-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

MMP14 CTSC SOAT1

6.72e-0520018358ff8db0ecf71daa86f9a38208e0d9b712cac0b5
ToppCellCOVID-19|World / group, cell type (main and fine annotations)

MMP14 CTSC SOAT1

6.72e-05200183ac38a468559c33ee00152735ce6e408f3f48df84
ToppCellmetastatic_Lymph_Node-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

MMP14 CTSC SOAT1

6.72e-052001834758b96725699641b55a665533adf2d238032b09
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

MMP14 CTSC SOAT1

6.72e-05200183195862a319794e57f0506757ae45ab70200bc5b4
ToppCellTCGA-Thryoid-Metastatic-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

TAAR9 SIGLEC7

6.60e-0495182ec7d723de94708f14997d82ab254bf5c9d4ed899
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Hilar/Perihilar-3|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

ABCA13 SYCP2

8.83e-041101820dde36429126d95d4e7efd91243ce6402ab11cdb
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MMP14 MAPRE3

1.05e-0312018216c3bd15e3936b68c433c4dd15d655aae64dc960
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT2_progenitor|E18.5-samps / Age Group, Lineage, Cell class and subclass

MTBP MIA2

1.14e-03125182b5fed0e0295aa8ad323c318b59bf23cde3e758c8
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABCA13 MIA2

1.16e-031261826cb89754010d64875e115da6c5805efac7a4a82d
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 MIA2

1.16e-0312618269b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCellIIH-CD4-CD8_2|IIH / Condition, Cell_class and T cell subcluster

SYCP2 ZNF551

1.36e-031371825614a086f5f698e0965f3c7699cffefec5c3b87e
ToppCelltumor_Lung-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

MMP16 CTSC

1.46e-03142182eaf08a0dbacc9ebbd54e377922e76d8ba854dcb8
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A9 ABCA13

1.53e-0314518296712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCelldroplet-Lung-nan-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC MIA2

1.55e-03146182ed932d43e9efd064ee4b49ddef529f3d041be765
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

MMP16 ABCA13

1.55e-03146182c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCelldroplet-Lung-nan-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC MIA2

1.55e-031461820d74962779055c774312d59fc3b1365163741c3a
ToppCellIIF-Lymphocyte-T_NK-dnT|IIF / Disease, Lineage and Cell Type

ABCA13 USP24

1.55e-03146182d0f361662db5f7be26104346e8431f7e30c5ce3a
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

MMP16 FERMT1

1.61e-03149182768877bade04ca0321593b8470b5011ad8270431
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 SYCP2

1.63e-031501826e806a028c0519489151c181d9907e05289e27e0
ToppCellP03-Epithelial-epithelial_progenitor_cell-epi_progenitor|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSC SOAT1

1.65e-03151182fce04bce66411c21cd5d4d41375f26f1f50f3348
ToppCellChildren_(3_yrs)-Immune-mast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAPRE3 FERMT1

1.65e-03151182bbf735c6433c3fc2feedb24ed6f48c51d545fb60
ToppCellMyeloid-C_(Monocyte)|World / shred on cell class and cell subclass (v4)

CTSC MIA2

1.67e-031521829145dc014ed7f154c158d454dc2b9754396afcca
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MMP16 FERMT1

1.70e-0315318261fe71e32fc9c8cad875bc087aad0b0ff680bf45
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 CTSC

1.76e-0315618221baf8c6e62bb7fd1530c2c100f73c0cecee092e
ToppCell368C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

AMFR MTBP

1.76e-031561821d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCell368C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

AMFR MTBP

1.76e-031561824877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 CTSC

1.76e-03156182c841faa1695ff577b0774f531adf1343d05dce9e
ToppCellASK452-Epithelial-Type_2|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

AMFR FERMT1

1.76e-03156182e2b8d65c38cedb8ec6c3c1b138957145af931c51
ToppCellChildren_(3_yrs)-Immune-mast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAPRE3 FERMT1

1.78e-03157182ec185dbeabb67fd9ca85f71cab88463b60f9b1c1
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_4|368C / Donor, Lineage, Cell class and subclass (all cells)

CTSC SIGLEC7

1.81e-03158182f9cfb110342be3c91aba9914805332f22ba89101
ToppCellIIF-Lymphocyte-T_NK-ILC|IIF / Disease, Lineage and Cell Type

SYCP2 ZNF551

1.83e-0315918255e4f21548f480ca414c00cbff5ec3b13bafd271
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SLC7A9 MMP14

1.85e-031601826d941e584360975e1fdbb2fc67af8e31f18759d8
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CTSC SYCP2

1.88e-031611827c9d4410d7142a5f3a05418c994f69978c9ffa17
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTSC SOAT1

1.90e-031621828e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC7A9 ABCA13

1.90e-03162182bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTSC SOAT1

1.90e-03162182e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCellBasal_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

ABCA13 FERMT1

1.92e-03163182679e25e5548d157d49a73057a3b5617dccda260f
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTSC MIA2

1.94e-03164182f88871d3b9307112eb7ced4c629f5704326ecae8
ToppCellfacs-Heart-LV-24m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC FERMT1

1.97e-0316518241707e66542ea27133043740ef9e58ab89b06607
ToppCellP07-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSC SOAT1

1.99e-03166182021b9344de7957762f81b09a647504b8c8289cf1
ToppCellfacs-Heart-LA-18m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC FERMT1

1.99e-0316618219ec59f0a43d4eb5b4cc7bcd6480ada7f469054b
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPRE3 SIGLEC7

1.99e-03166182a42268a02a89fc97272e45c4cbe21acf04b7428c
ToppCellSigmoid-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

MMP14 SOAT1

2.04e-03168182bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCelldroplet-Fat-Scat-18m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC SOAT1

2.04e-0316818202dfe8037e61f9d4ac5f8df3929673bc212fd2cd
ToppCellfacs-Lung-18m-Hematologic-myeloid-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTSC SOAT1

2.04e-031681820ffad93ba2fb5d4cfda2c13011059555475dcfc8
ToppCellP28-Epithelial-epithelial_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSC SOAT1

2.04e-0316818203c95ad3684caec7a6d581006b237cc5fa230685
ToppCelldroplet-Fat-Scat-18m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC SOAT1

2.04e-0316818294916feefd413c84bb7d3fd2d3e403036b705b69
ToppCellfacs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTSC SOAT1

2.04e-03168182ab1fb9b2cc7c5853b7fbd373e1784a9a31f96d38
ToppCellPCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ZNF551 SIGLEC7

2.06e-0316918245ac692a0c9064ce6b6a31c2cd21c85ccf594670
ToppCell356C-Epithelial_cells-Epithelial-D_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SYCP2 SIGLEC7

2.06e-03169182818ab7a6fd1940a22d3bd99fe15f0af888af6b3e
ToppCellPCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_natural_killer_[NK]_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ZNF551 SIGLEC7

2.06e-031691823514a74980c7bd4bb76dbd06693f492e8dce21e0
ToppCellfacs-Lung-nan-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC SOAT1

2.06e-03169182bf0a97f53d6e3f9ffeaeae0402b010c49a6cccb7
ToppCell356C-Epithelial_cells-Epithelial-D_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SYCP2 SIGLEC7

2.06e-03169182f982f2e0d341fa27229f443ebe5c0e4a9e63bda6
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSC SOAT1

2.06e-0316918253e863de064d44e1d36e21fb3dbba37ae020f6e9
ToppCellP07-Epithelial-epithelial_progenitor_cell-epi_progenitor|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSC SOAT1

2.06e-031691821a47a4892a5e6a69555f5332308503526e5422a7
ToppCellP07-Epithelial-epithelial_progenitor_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSC SOAT1

2.06e-03169182ec23caecbb0d969307e33e9df8499ddcd1420305
ToppCelldroplet-Pancreas-Exocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP14 FERMT1

2.06e-0316918253690d6f9712b54aa99a0408aae930d64ae478e5
ToppCellfacs-Lung-nan-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC SOAT1

2.06e-0316918205b138511039f1255a5f647040b1b9bdf222bd52
ToppCellP28-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSC SOAT1

2.09e-03170182d0ed3a8a7ad96c05641ec409b0a69c4fb094893c
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP14 CTSC

2.09e-03170182067657ca7fcf5a0ffbd168b5c4609a30ca508f22
ToppCellP15-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSC SOAT1

2.09e-031701826c0619cbe2f01a6de18da0a137f92bda0cbdf075
ToppCellP03-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSC SOAT1

2.09e-031701823fd37e9b377d6485cea1262c31a8507d18a78514
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA13 CTSC

2.11e-03171182fe27bf581c75ef33c2848878e51ed16b275a4c8e
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA13 CTSC

2.11e-0317118225c1979e972c959e1ce4c57804f976f53a247ad7
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA13 CTSC

2.14e-03172182afa36501d48b1456c511fa0d5d326ec05bdc380f
ToppCelldroplet-Lung-nan-18m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC MIA2

2.14e-0317218298cb64e2a768908105701a7a5b58f336036250fd
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

ABCA13 FERMT1

2.14e-03172182a66402d15853f0c9e3d06394ff9ac08d1da128ff
ToppCelldroplet-Lung-nan-18m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC MIA2

2.14e-0317218235d09640d5b04fa0bbb1b40d4b8f97da587a5046
ToppCelldroplet-Fat-Scat-18m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC SOAT1

2.14e-031721828a4a5ad65eec92ce4fa45c5aa01c28666307455b
ToppCellfacs-BAT-Fat-3m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC SOAT1

2.14e-031721825f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCellASK454-Immune-NK_cell|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

SIGLEC7 MIA2

2.14e-03172182c9e738c3540ee09b08805b1cdb66b4a0d9d40d33
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP14 FERMT1

2.14e-031721823f784aed340b50ddbec3f7dc0a5279180d38a2bb
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT2|E18.5-samps / Age Group, Lineage, Cell class and subclass

CTSC SOAT1

2.16e-03173182f6e36ea98a9c669ff393d141455aaecef083f738
ToppCellIonocyte-iono-2|World / Class top

SYCP2 SOAT1

2.16e-03173182e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCelldroplet-Fat-Gat-18m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FERMT1 MIA2

2.16e-03173182a40a52d8041d45dc3bef74fe55945ae07aa018d6
ToppCellP07-Epithelial|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSC SOAT1

2.16e-031731828b10087a917b825809d35a2b2b349c73a2782472
ToppCellEpithelial-Epithelial-C_(AT2)|Epithelial / shred on cell class and cell subclass (v4)

CTSC SOAT1

2.16e-03173182f57cbf5bd2a9e5db47b4919e9cd5e50781c1a990
ToppCelldroplet-Fat-Gat-18m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FERMT1 MIA2

2.16e-03173182f0b4dd1cf41d6ee6abb0e1968b8b39f4fabebcb5
ToppCelldroplet-Fat-Gat-18m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FERMT1 MIA2

2.16e-03173182f3f67531f72d6d52e19c7f1f2db1ab4026fb70da
ToppCellP03-Epithelial-epithelial_progenitor_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSC SOAT1

2.18e-0317418223c7fdfc73170cfc5cdee5bb7fbee0c8bbbbca07
ToppCellE17.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSC SOAT1

2.18e-0317418268914ec843f58ecff3e6412544a341daf8a01cac
ToppCellP07-Epithelial-alveolar_epithelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CTSC SOAT1

2.18e-031741822739de68e0266054694f99807cfb1f07b6bbb371
ToppCellControl-Myeloid-MoAM2,_CCL18|Control / Condition, Lineage and Cell class

SLC7A9 MMP14

2.18e-031741824c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTSC SOAT1

2.18e-0317418202ab165b064acb91f2d3f59cc5be195899d61a83
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

MAPRE3 SYCP2

2.18e-03174182390bd41ef114464f3db3e0cac4e67fe7571b4c23
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ABCA13 FERMT1

2.18e-031741829e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ComputationalGenes in the cancer module 321.

CTSC SOAT1 SIGLEC7

2.92e-04112133MODULE_321
DrugGossypol [303-45-7]; Up 200; 7.8uM; PC3; HT_HG-U133A

MMP14 MMP16 MAPRE3 MIA2

1.11e-051821843740_UP
Drug(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; PC3; HT_HG-U133A

MMP14 AMFR MAPRE3 MED31

1.40e-051931845050_DN
DrugMethotrimeprazine maleat salt [7104-38-3]; Up 200; 9uM; MCF7; HT_HG-U133A

MMP16 AMFR SOAT1 ZNF551

1.45e-051951844723_UP
DrugAcetazolamide [59-66-5]; Down 200; 18uM; MCF7; HT_HG-U133A

AMFR CTSC MIA2 USP24

1.48e-051961841686_DN
DrugICI182,780; Down 200; 1uM; PC3; HT_HG-U133A

MMP14 AMFR MAPRE3 SIGLEC7

1.51e-051971846867_DN
DrugLincomycin hydrochloride [859-18-7]; Up 200; 9uM; MCF7; HT_HG-U133A

MMP14 MMP16 MAPRE3 MIA2

1.51e-051971847411_UP
DrugCGS 27023A

MMP14 MMP16

2.12e-059182ctd:C097658
Drugtd x

SOAT1 USP24

1.48e-0423182CID000447462
Drughomophenylalanine

MMP14 CTSC

2.53e-0430182CID000102530
DrugAC1MT1OO

CTSC SYCP2

2.89e-0432182CID003593510
Drugmalolactomycin D

MMP14 MMP16

2.89e-0432182CID006449115
DrugAC1NRA2F

CTSC SOAT1

3.66e-0436182CID005287663
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A

AMFR SOAT1 SIGLEC7

4.00e-041861831612_UP
Drugcarmustine; Up 200; 100uM; PC3; HT_HG-U133A

MMP14 MMP16 SIGLEC7

4.06e-041871836883_UP
DrugMonobenzone [103-16-2]; Down 200; 20uM; MCF7; HT_HG-U133A

AMFR CTSC MIA2

4.19e-041891835312_DN
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A

MMP16 SYCP2 MIA2

4.39e-041921834743_DN
DrugFamprofazone [22881-35-2]; Down 200; 10.6uM; PC3; HT_HG-U133A

MMP14 AMFR MED31

4.39e-041921833753_DN
DrugLetrozole [112809-51-5]; Down 200; 14uM; PC3; HT_HG-U133A

MMP14 MAPRE3 SYCP2

4.46e-041931834240_DN
Drug(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; PC3; HT_HG-U133A

MAPRE3 SYCP2 MED31

4.46e-041931833810_DN
Drug(S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; MCF7; HT_HG-U133A

MMP16 MAPRE3 SOAT1

4.46e-041931833870_UP
DrugCefalonium [5575-21-3]; Down 200; 8.8uM; PC3; HT_HG-U133A

MMP14 MAPRE3 MED31

4.46e-041931834245_DN
DrugQuinethazone [73-49-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A

SLC7A9 AMFR MAPRE3

4.52e-041941833875_DN
DrugCinchonine [118-10-5]; Down 200; 13.6uM; PC3; HT_HG-U133A

SLC7A9 MMP14 MAPRE3

4.52e-041941833988_DN
Drugcalmidazolium chloride; Down 200; 5uM; MCF7; HT_HG-U133A_EA

AMFR SOAT1 USP24

4.52e-04194183906_DN
DrugAntazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; HL60; HG-U133A

SLC7A9 MMP14 SOAT1

4.52e-041941831556_UP
DrugEthoxyquin [91-53-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A

MMP14 MMP16 MAPRE3

4.52e-041941833846_UP
DrugNifedipine [21829-25-4]; Down 200; 11.6uM; HL60; HT_HG-U133A

SOAT1 FERMT1 MIA2

4.52e-041941831856_DN
Drugalpha-Santonin [481-06-1]; Up 200; 16.2uM; PC3; HT_HG-U133A

MMP14 MMP16 SOAT1

4.52e-041941834531_UP
DrugBufexamac [2438-72-4]; Up 200; 18uM; HL60; HT_HG-U133A

AMFR FERMT1 SIGLEC7

4.59e-041951832382_UP
Drugestradiol; Down 200; 0.01uM; PC3; HT_HG-U133A

SLC7A9 MMP16 SYCP2

4.59e-041951835910_DN
Drug2-propylpentanoic acid; Down 200; 1000uM; PC3; HT_HG-U133A

MMP16 MAPRE3 MIA2

4.59e-041951834433_DN
DrugCephalexin monohydrate [23325-78-2]; Up 200; 11uM; HL60; HT_HG-U133A

AMFR SIGLEC7 MIA2

4.59e-041951831273_UP
DrugThioperamide maleate [106243-16-7]; Down 200; 9.8uM; MCF7; HT_HG-U133A

MMP14 MMP16 MAPRE3

4.59e-041951833392_DN
DrugHalofantrine hydrochloride [36167-63-2]; Up 200; 7.4uM; MCF7; HT_HG-U133A

MMP16 ZNF551 MIA2

4.59e-041951837469_UP
DrugEtofenamate [30544-47-9]; Up 200; 10.8uM; HL60; HT_HG-U133A

MMP14 MMP16 SIGLEC7

4.59e-041951832907_UP
DrugVerapamyl hydrochloride [152-11-4]; Up 200; 8.2uM; PC3; HG-U133A

SOAT1 SIGLEC7 USP24

4.59e-041951831927_UP
DrugIsopropamide iodide [71-81-8]; Down 200; 8.4uM; MCF7; HT_HG-U133A

MMP16 SYCP2 MIA2

4.59e-041951833461_DN
DrugChloramphenicol [56-75-7]; Up 200; 12.4uM; HL60; HT_HG-U133A

MMP14 FERMT1 SIGLEC7

4.59e-041951831837_UP
DrugZalcitabine [7481-89-2]; Up 200; 19uM; MCF7; HT_HG-U133A

MMP14 MMP16 SOAT1

4.59e-041951834799_UP
DrugCarisoprodol [78-44-4]; Down 200; 15.4uM; PC3; HT_HG-U133A

MMP14 MMP16 ZNF551

4.66e-041961836610_DN
DrugPipenzolate bromide [125-51-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A

MMP16 MAPRE3 MIA2

4.66e-041961836821_UP
Drughaloperidol; Up 200; 10uM; MCF7; HT_HG-U133A_EA

SOAT1 FERMT1 MIA2

4.66e-041961831041_UP
Drug2-propylpentanoic acid; Up 200; 500uM; MCF7; HG-U133A

MMP16 SOAT1 MED31

4.66e-04196183347_UP
DrugAmpyrone [83-07-8]; Up 200; 19.6uM; MCF7; HT_HG-U133A

MMP14 MMP16 AMFR

4.66e-041961836845_UP
DrugSotalol hydrochloride [959-24-0]; Up 200; 13uM; MCF7; HT_HG-U133A

MMP16 AMFR USP24

4.66e-041961837338_UP
DrugAcacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A

SLC7A9 AMFR SIGLEC7

4.66e-041961833849_DN
Drugquercetin dihydrate; Up 200; 1uM; MCF7; HT_HG-U133A_EA

MMP16 MAPRE3 SYCP2

4.66e-04196183917_UP
DrugKetoprofen [22071-15-4]; Up 200; 15.8uM; PC3; HT_HG-U133A

MMP14 MMP16 MIA2

4.66e-041961833729_UP
DrugTridihexethyl chloride; Up 200; 11.4uM; HL60; HT_HG-U133A

MMP14 SIGLEC7 MIA2

4.66e-041961832964_UP
DrugBenzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A

MMP16 MAPRE3 SYCP2

4.66e-041961834760_DN
DrugTolazamide [1156-19-0]; Down 200; 12.8uM; PC3; HT_HG-U133A

MMP14 MAPRE3 MED31

4.66e-041961834003_DN
Drug5253409; Down 200; 17uM; MCF7; HT_HG-U133A_EA

MMP16 AMFR ZNF551

4.66e-04196183844_DN
DrugHydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; HL60; HT_HG-U133A

MMP14 SYCP2 SIGLEC7

4.66e-041961832430_UP
DrugPrilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; MCF7; HT_HG-U133A

MAPRE3 SYCP2 FERMT1

4.66e-041961834749_DN
DrugNifedipine [21829-25-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A

SYCP2 FERMT1 MIA2

4.66e-041961831692_DN
Drugikarugamycin; Up 200; 2uM; MCF7; HT_HG-U133A_EA

MMP14 AMFR MAPRE3

4.66e-04196183918_UP
DrugParomomycin sulfate [1263-89-4]; Up 200; 5.6uM; MCF7; HT_HG-U133A

SLC7A9 MAPRE3 MED31

4.66e-041961834420_UP
DrugBergenin monohydrate [477-90-7]; Up 200; 11.6uM; HL60; HT_HG-U133A

MAPRE3 FERMT1 SIGLEC7

4.66e-041961832726_UP
DrugClemizole hydrochloride [1163-36-6]; Up 200; 11uM; MCF7; HT_HG-U133A

MAPRE3 ZNF551 SIGLEC7

4.66e-041961832301_UP
DrugTinidazole [19387-91-8]; Down 200; 16.2uM; PC3; HT_HG-U133A

AMFR MIA2 USP24

4.66e-041961834548_DN
DrugIopromide [73334-07-3]; Up 200; 5uM; PC3; HT_HG-U133A

MMP14 MAPRE3 MED31

4.73e-041971834504_UP
DrugMolindone hydrochloride [15622-65-8]; Up 200; 12.8uM; PC3; HT_HG-U133A

MMP16 SYCP2 SOAT1

4.73e-041971834199_UP
DrugOleandomycin phosphate [7060-74-4]; Down 200; 5uM; MCF7; HT_HG-U133A

MMP16 AMFR FERMT1

4.73e-041971831518_DN
DrugCefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A

AMFR SOAT1 MED31

4.73e-041971834708_UP
DrugDehydrocholic acid [81-23-2]; Up 200; 9.6uM; PC3; HT_HG-U133A

SLC7A9 MMP16 SYCP2

4.73e-041971834620_UP
DrugPicotamide monohydrate [80530-63-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A

MMP14 MMP16 MIA2

4.73e-041971832233_DN
DrugThiamphenicol [15318-45-3]; Up 200; 11.2uM; PC3; HT_HG-U133A

AMFR SOAT1 USP24

4.73e-041971831826_UP
DrugBenfotiamine [22457-89-2]; Up 200; 8.6uM; HL60; HT_HG-U133A

MMP14 MED31 MIA2

4.73e-041971832177_UP
Drugestradiol, USP; Up 200; 0.01uM; HL60; HT_HG-U133A

SLC7A9 SOAT1 SIGLEC7

4.73e-041971831182_UP
DrugScopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; MCF7; HT_HG-U133A

MMP14 SYCP2 MIA2

4.73e-041971835436_DN
DrugPindolol [13523-86-9]; Down 200; 16.2uM; HL60; HG-U133A

AMFR SIGLEC7 USP24

4.73e-041971831392_DN
DrugGlycopyrrolate [596-51-0]; Up 200; 10uM; HL60; HT_HG-U133A

AMFR MAPRE3 MED31

4.73e-041971832565_UP
DrugAceclofenac [89796-99-6]; Up 200; 11.2uM; PC3; HT_HG-U133A

MMP14 AMFR SYCP2

4.73e-041971832117_UP
DrugEthoxyquin [91-53-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A

SLC7A9 MMP16 AMFR

4.73e-041971833846_DN
DrugLysergol [602-85-7]; Down 200; 15.8uM; PC3; HT_HG-U133A

MMP14 MMP16 MIA2

4.73e-041971836621_DN
DrugSulindac [38194-50-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A

AMFR FERMT1 USP24

4.73e-041971831693_DN
DrugSC 19220; Down 200; 10uM; MCF7; HT_HG-U133A

SYCP2 SOAT1 ZNF551

4.73e-041971837060_DN
Drugfluphenazine dihydrochloride; Up 200; 10uM; PC3; HT_HG-U133A

MMP14 SYCP2 MIA2

4.73e-041971831237_UP
DrugDicumarol [66-76-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A

AMFR SIGLEC7 MIA2

4.73e-041971833848_DN
Drug11-deoxy-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A

MAPRE3 SYCP2 SIGLEC7

4.73e-041971837533_UP
DrugMelatonin [73-31-4]; Up 200; 17.2uM; HL60; HT_HG-U133A

SYCP2 FERMT1 USP24

4.80e-041981832431_UP
DrugSulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A

AMFR SIGLEC7 MIA2

4.80e-041981833847_DN
DrugNorethynodrel [68-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A

ZNF551 MED31 SIGLEC7

4.80e-041981837471_UP
DrugChlorprothixene hydrochloride [6469-93-8]; Up 200; 11.4uM; HL60; HT_HG-U133A

MED31 SIGLEC7 USP24

4.80e-041981831272_UP
Drugpioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A

MMP16 SIGLEC7 MIA2

4.80e-041981837506_DN
DrugUrapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; MCF7; HT_HG-U133A

MMP14 MMP16 MAPRE3

4.80e-041981836455_UP
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

SYCP2 ZNF551 MIA2

4.80e-041981834348_DN
DrugOfloxacin [82419-36-1]; Up 200; 11uM; HL60; HT_HG-U133A

AMFR FERMT1 SIGLEC7

4.80e-041981832340_UP
DrugZidovudine, AZT [30516-87-1]; Up 200; 15uM; HL60; HG-U133A

AMFR MED31 SIGLEC7

4.80e-041981831595_UP
Drugestradiol, USP; Down 200; 0.1uM; PC3; HT_HG-U133A

MMP16 AMFR MIA2

4.80e-041981834432_DN
DrugDorzolamide hydrochloride [130693-82-2]; Down 200; 11uM; MCF7; HT_HG-U133A

SYCP2 SOAT1 MIA2

4.80e-041981833565_DN
DrugSulfasalazine [599-79-1]; Up 200; 10uM; MCF7; HT_HG-U133A

SLC7A9 MMP16 ZNF551

4.80e-041981835446_UP
DrugTrapidil [15421-84-8]; Up 200; 19.4uM; MCF7; HT_HG-U133A

SLC7A9 MMP14 SYCP2

4.80e-041981837475_UP
DrugChlorzoxazone [95-25-0]; Down 200; 23.6uM; PC3; HT_HG-U133A

AMFR ZNF551 USP24

4.80e-041981832100_DN
Drugmonastrol; Up 200; 100uM; PC3; HG-U133A

MMP14 MED31 SIGLEC7

4.80e-04198183668_UP
DrugFlunixin meglumine [42461-84-7]; Up 200; 8.2uM; PC3; HT_HG-U133A

SLC7A9 MMP16 MAPRE3

4.80e-041981834273_UP
Drug(1)-Nipecotic acid [498-95-3]; Down 200; 31uM; MCF7; HT_HG-U133A

MMP14 SYCP2 MIA2

4.80e-041981836500_DN
DrugOxytetracycline dihydrate [6153-64-6]; Up 200; 8uM; HL60; HG-U133A

MMP14 SOAT1 MED31

4.80e-041981831553_UP
DrugCephapirin sodium salt [24356-60-3]; Down 200; 9uM; HL60; HT_HG-U133A

SLC7A9 AMFR SIGLEC7

4.80e-041981832730_DN
DrugAminocaproic acid [60-32-2]; Down 200; 30.4uM; MCF7; HT_HG-U133A

SYCP2 MIA2 USP24

4.80e-041981836501_DN
DiseaseDisease Exacerbation

ABCA13 AMFR CTSC

1.56e-04165193C0235874
Diseasebrain ischemia (biomarker_via_orthology)

MMP14 CTSC

1.95e-03102192DOID:2316 (biomarker_via_orthology)
Diseasepeptide measurement

MMP16 ABCA13

2.22e-03109192EFO_0010520
Diseaseresponse to paliperidone, schizophrenia symptom severity measurement

CTSC USP24

8.40e-03216192EFO_0007925, EFO_0007927

Protein segments in the cluster

PeptideGeneStartEntry
QYWFIFKDTSIAYFK

FERMT1

391

Q9BQL6
QFFLEQAYYWKAFKK

ABCA13

631

Q86UQ4
YFYKGNKYWKFNNQK

MMP14

476

P50281
KAFVNYLKYLLYWKD

MED31

46

Q9Y3C7
YTFNKQSKDWYAYKL

CST9LP1

56

Q5W188
YFLFVHYKFGWAQKI

SLC7A9

451

P82251
LNDYKWFAFFKYKEE

CTSC

96

P53634
EFIQWFKKFFDANYD

MAPRE3

106

Q9UPY8
SKKWFFAVQAIYGFY

MTBP

76

Q96DY7
YLKKFLYNFDNPWNF

MIA2

456

Q96PC5
YAYKDFLWFFSKRFK

SOAT1

431

P35610
YAFFYQWFGKAIKLI

TAAR9

311

Q96RI9
YFFRMEKGNIKWNYK

SIGLEC7

121

Q9Y286
QHLKDKFWNFIFYKF

AMFR

116

Q9UKV5
GNFVFFKGNKYWVFK

MMP16

401

P51512
FYKGKEYWKFNNQIL

MMP16

501

P51512
DFWEKIFQKFSAYQK

SYCP2

1441

Q9BX26
KHIQAFFNAKSYYKW

ZNF551

211

Q7Z340
KLQYYVPENFWKIFK

USP24

1746

Q9UPU5
VLYFDFWFQIFNMKK

UGT2B10

216

P36537