Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

NID2 TRPM4 PEF1 STAB2 FBN1 HMCN2 MEGF6 CD248 CUBN LTBP4 ATP2B2 PCDH17 NOTCH3 NOTCH4

4.59e-077497314GO:0005509
GeneOntologyMolecularFunctionWnt-protein binding

FZD1 ROR1 ROR2 LRP5

7.02e-0634734GO:0017147
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

ROR1 ROR2 LTBP4 EPHA1 NRP1

1.48e-0585735GO:0019199
GeneOntologyMolecularFunctionWnt receptor activity

FZD1 ROR1 LRP5

3.07e-0517733GO:0042813
GeneOntologyMolecularFunctionextracellular matrix structural constituent

NID2 FBN1 HMCN2 LAMA5 LTBP4 SSPOP

6.49e-05188736GO:0005201
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

ROR1 ROR2 EPHA1 NRP1

9.40e-0565734GO:0004714
GeneOntologyMolecularFunctioncoreceptor activity

ROR1 ROR2 LRP5 NRP1

1.40e-0472734GO:0015026
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

KMT2C KMT2D

3.64e-048732GO:0140945
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

KMT2C KMT2D SETD5

5.57e-0444733GO:0140938
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

KMT2C KMT2D

5.82e-0410732GO:0140999
GeneOntologyMolecularFunctionarylsulfatase activity

GALNS ARSD

1.17e-0314732GO:0004065
GeneOntologyMolecularFunctionsulfuric ester hydrolase activity

GALNS ARSD

1.73e-0317732GO:0008484
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

ROR1 ROR2 EPHA1 NRP1

1.97e-03145734GO:0004713
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

KMT2C KMT2D SETD5

1.98e-0368733GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

KMT2C KMT2D SETD5

2.07e-0369733GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

KMT2C KMT2D SETD5

2.24e-0371733GO:0042054
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2C KMT2D

2.40e-0320732GO:0042800
GeneOntologyMolecularFunctionK48-linked deubiquitinase activity

USP9X USP15

2.65e-0321732GO:1990380
GeneOntologyBiologicalProcesssynapse organization

FZD1 HMCN2 SETD5 USP9X ROR2 LAMA5 LRP5 CSMD2 ATP2B2 PCDH17 NRP1

1.82e-056857011GO:0050808
GeneOntologyBiologicalProcessneuron projection development

FZD1 ARID1B HMCN2 KREMEN1 FEZF1 USP9X ROR1 ROR2 FIGNL2 ETV1 LAMA5 ATP2B2 NOTCH3 NRP1

8.90e-0512857014GO:0031175
GeneOntologyBiologicalProcesscell junction organization

FZD1 HMCN2 TRIP6 SETD5 USP9X ROR2 LAMA5 LRP5 CSMD2 ATP2B2 PCDH17 NRP1

9.72e-059747012GO:0034330
GeneOntologyBiologicalProcessregulation of insulin secretion

TRPM4 FBN1 TRPA1 LRP5 NOS2 ADCY5

1.33e-04231706GO:0050796
GeneOntologyBiologicalProcesstrunk neural crest cell migration

LAMA5 NRP1

1.69e-046702GO:0036484
GeneOntologyBiologicalProcesstrunk segmentation

LAMA5 NRP1

1.69e-046702GO:0035290
GeneOntologyBiologicalProcessrenal system vasculature morphogenesis

NOTCH3 NRP1

2.36e-047702GO:0061438
GeneOntologyBiologicalProcesskidney vasculature morphogenesis

NOTCH3 NRP1

2.36e-047702GO:0061439
GeneOntologyBiologicalProcessregulation of insulin secretion involved in cellular response to glucose stimulus

TRPM4 TRPA1 LRP5 ADCY5

2.71e-0492704GO:0061178
GeneOntologyBiologicalProcessaxon development

HMCN2 KREMEN1 FEZF1 USP9X FIGNL2 ETV1 LAMA5 NOTCH3 NRP1

3.10e-04642709GO:0061564
GeneOntologyBiologicalProcessinsulin secretion

TRPM4 FBN1 TRPA1 LRP5 NOS2 ADCY5

3.35e-04274706GO:0030073
GeneOntologyBiologicalProcessneuron development

FZD1 ARID1B HMCN2 KREMEN1 FEZF1 USP9X ROR1 ROR2 FIGNL2 ETV1 LAMA5 ATP2B2 NOTCH3 NRP1

3.44e-0414637014GO:0048666
GeneOntologyBiologicalProcessregulation of peptide hormone secretion

TRPM4 FBN1 TRPA1 LRP5 NOS2 ADCY5

3.55e-04277706GO:0090276
GeneOntologyBiologicalProcessregulation of peptide transport

TRPM4 FBN1 TRPA1 LRP5 NOS2 ADCY5

3.90e-04282706GO:0090087
GeneOntologyBiologicalProcessregulation of peptide secretion

TRPM4 FBN1 TRPA1 LRP5 NOS2 ADCY5

3.90e-04282706GO:0002791
GeneOntologyBiologicalProcessinsulin secretion involved in cellular response to glucose stimulus

TRPM4 TRPA1 LRP5 ADCY5

4.02e-04102704GO:0035773
GeneOntologyBiologicalProcessaxon guidance

HMCN2 FEZF1 ETV1 LAMA5 NOTCH3 NRP1

4.13e-04285706GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

HMCN2 FEZF1 ETV1 LAMA5 NOTCH3 NRP1

4.20e-04286706GO:0097485
GeneOntologyCellularComponentcell surface

FZD1 TSPAN15 NID2 STAB2 CD248 ROR1 ROR2 ITGA10 PLAUR CUBN ADGRA3 NOTCH3 NOTCH4 NRP1

3.03e-0511117414GO:0009986
GeneOntologyCellularComponentextracellular matrix

NID2 FBN1 FCGBP HMCN2 MEGF6 CD248 ADAMTS2 LAMA5 LTBP4 SSPOP

1.02e-046567410GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

NID2 FBN1 FCGBP HMCN2 MEGF6 CD248 ADAMTS2 LAMA5 LTBP4 SSPOP

1.04e-046587410GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

NID2 FBN1 HMCN2 MEGF6 ADAMTS2 LAMA5 LTBP4 SSPOP

5.62e-04530748GO:0062023
GeneOntologyCellularComponentMLL3/4 complex

KMT2C KMT2D

7.97e-0412742GO:0044666
GeneOntologyCellularComponentbasement membrane

NID2 FBN1 HMCN2 LAMA5

9.27e-04122744GO:0005604
GeneOntologyCellularComponentmicrofibril

FBN1 LTBP4

9.40e-0413742GO:0001527
GeneOntologyCellularComponentreceptor complex

ROR1 ROR2 ITGA10 LRP5 CUBN NOTCH3 EPHA1 NRP1

1.02e-03581748GO:0043235
GeneOntologyCellularComponentWnt signalosome

FZD1 LRP5

1.44e-0316742GO:1990909
HumanPhenoInguinal hernia

KMT2C ARID1B KMT2D FBN1 GALNS ADAMTS2 ROR2 LTBP4 NOTCH3

9.22e-06312259HP:0000023
HumanPhenoBlue sclerae

ZNF469 KMT2D FBN1 ADAMTS2 ROR2 LRP5

1.01e-05108256HP:0000592
HumanPhenoAbnormality of the dentition

TRPM4 KMT2C ZNF469 ARID1B KMT2D FBN1 GALNS KREMEN1 ADAMTS2 FEZF1 SETD5 USP9X ROR2 LRP5 NOTCH3

1.47e-0510302515HP:0000164
HumanPhenoJoint hypermobility

ZNF469 ARID1B KMT2D FBN1 GALNS ADAMTS2 USP9X ROR2 LRP5 LTBP4 NOTCH3

2.57e-055572511HP:0001382
HumanPhenoAbnormal sclera morphology

ZNF469 KMT2D FBN1 ADAMTS2 ROR2 LRP5

4.64e-05141256HP:0000591
HumanPhenoShort phalanx of finger

ARID1B KMT2D FBN1 ADAMTS2 SETD5 USP9X ROR2 LAMA5

6.80e-05306258HP:0009803
HumanPhenoAplasia/Hypoplasia of the phalanges of the hand

ARID1B KMT2D FBN1 ADAMTS2 SETD5 USP9X ROR2 LAMA5

9.15e-05319258HP:0009767
HumanPhenoTooth malposition

KMT2D FBN1 GALNS ADAMTS2 SETD5 USP9X ROR2 LRP5 NOTCH3

9.62e-05418259HP:0000692
HumanPhenoAbnormality of external features of the abdomen

KMT2C ARID1B KMT2D FBN1 ADAMTS2 ROR2 LTBP4 NOTCH3

1.07e-04326258HP:0001462
HumanPhenoAbnormal sacrum morphology

ARID1B KMT2D SETD5 USP9X ROR2 NOTCH3

1.20e-04167256HP:0005107
HumanPhenoSacral dimple

ARID1B KMT2D SETD5 USP9X ROR2

1.61e-04110255HP:0000960
HumanPhenoAbnormality of the abdominal wall

KMT2C ARID1B KMT2D FBN1 GALNS ADAMTS2 USP9X ROR2 LTBP4 NOTCH3

1.67e-045602510HP:0004298
HumanPhenoSacrococcygeal pilonidal abnormality

ARID1B KMT2D SETD5 USP9X ROR2

1.91e-04114255HP:0010767
HumanPhenoSkin dimple

ARID1B KMT2D SETD5 USP9X ROR2

2.43e-04120255HP:0010781
HumanPhenoHernia

KMT2C ZNF469 ARID1B KMT2D FBN1 GALNS ADAMTS2 ROR2 LTBP4 NOTCH3

2.56e-045892510HP:0100790
HumanPhenoThick vermilion border

KMT2C ARID1B KMT2D FBN1 KREMEN1 ADAMTS2 USP9X

2.81e-04279257HP:0012471
HumanPhenoMotor delay

KMT2C ARID1B KMT2D FBN1 GALNS ADAMTS2 SETD5 ROR1 LRP5 CUBN LTBP4 ADCY5 NOTCH3

3.53e-0410182513HP:0001270
HumanPhenoDownslanted palpebral fissures

ARID1B KMT2D FBN1 KREMEN1 ADAMTS2 SETD5 USP9X ROR2 NOTCH3

3.65e-04497259HP:0000494
HumanPhenoHernia of the abdominal wall

KMT2C ARID1B KMT2D FBN1 GALNS ADAMTS2 ROR2 LTBP4 NOTCH3

4.17e-04506259HP:0004299
HumanPhenoKyphosis

KMT2C ARID1B KMT2D FBN1 GALNS SETD5 ROR2 LRP5 NOTCH3

4.43e-04510259HP:0002808
HumanPhenoAbdominal wall defect

KMT2C ARID1B KMT2D FBN1 GALNS ADAMTS2 ROR2 LTBP4 NOTCH3

4.50e-04511259HP:0010866
HumanPhenoThoracoabdominal wall defect

KMT2C ARID1B KMT2D FBN1 GALNS ADAMTS2 ROR2 LTBP4 NOTCH3

4.50e-04511259HP:0100656
HumanPhenoLocalized skin lesion

TRPM4 ZNF469 ARID1B KMT2D FBN1 ADAMTS2 SETD5 USP9X ROR2 LRP5 NOTCH3 DDX11

4.53e-048972512HP:0011355
HumanPhenoUmbilical hernia

KMT2C ARID1B FBN1 ADAMTS2 ROR2 LTBP4 NOTCH3

4.95e-04306257HP:0001537
HumanPhenoAbnormal curvature of the vertebral column

KMT2C ZNF469 ARID1B KMT2D FBN1 GALNS ADAMTS2 SETD5 USP9X ROR2 LRP5 LTBP4 ADCY5 NOTCH3

5.52e-0412192514HP:0010674
HumanPhenoAbnormal umbilicus morphology

KMT2C ARID1B FBN1 ADAMTS2 ROR2 LTBP4 NOTCH3

5.67e-04313257HP:0001551
HumanPhenoAbnormal hip bone morphology

ZNF469 ARID1B KMT2D FBN1 GALNS ADAMTS2 USP9X ROR2 LAMA5 LRP5

5.98e-046532510HP:0003272
HumanPhenoAbnormal cardiac septum morphology

ARID1B KMT2D FBN1 SETD5 USP9X ROR2 LAMA5 LRP5 LTBP4 NOTCH3 DDX11

6.19e-047872511HP:0001671
DomainEGF_2

NID2 HGFAC STAB2 FBN1 HMCN2 MEGF6 CD248 LAMA5 LRP5 CUBN LTBP4 SSPOP MEGF11 NOTCH3 NOTCH4 EPHA1

5.53e-152657416PS01186
DomainEGF-like_dom

NID2 HGFAC STAB2 FBN1 FCGBP HMCN2 MEGF6 CD248 LAMA5 LRP5 CUBN LTBP4 MEGF11 NOTCH3 NOTCH4

4.44e-142497415IPR000742
DomainEGF-like_CS

NID2 HGFAC STAB2 FBN1 HMCN2 MEGF6 CD248 LAMA5 LRP5 CUBN LTBP4 MEGF11 NOTCH3 NOTCH4 EPHA1

8.85e-142617415IPR013032
DomainEGF_3

NID2 HGFAC STAB2 FBN1 HMCN2 MEGF6 CD248 LRP5 CUBN LTBP4 SSPOP MEGF11 NOTCH3 NOTCH4

3.95e-132357414PS50026
DomainEGF

NID2 HGFAC STAB2 FBN1 FCGBP MEGF6 CD248 LAMA5 LRP5 CUBN LTBP4 MEGF11 NOTCH3 NOTCH4

3.95e-132357414SM00181
DomainGrowth_fac_rcpt_

NID2 STAB2 FBN1 HMCN2 MEGF6 CD248 LAMA5 CUBN LTBP4 NOTCH3 NOTCH4 EPHA1

1.06e-121567412IPR009030
DomainEGF_1

HGFAC STAB2 FBN1 HMCN2 MEGF6 CD248 LAMA5 LRP5 CUBN LTBP4 SSPOP MEGF11 NOTCH3 NOTCH4

1.20e-122557414PS00022
DomainEGF-like_Ca-bd_dom

NID2 STAB2 FBN1 HMCN2 MEGF6 CD248 LRP5 CUBN LTBP4 NOTCH3 NOTCH4

2.07e-121247411IPR001881
DomainEGF_CA

NID2 FBN1 HMCN2 MEGF6 CD248 LRP5 CUBN LTBP4 NOTCH3 NOTCH4

5.97e-12997410PS01187
DomainEGF_CA

NID2 STAB2 FBN1 HMCN2 MEGF6 CD248 CUBN LTBP4 NOTCH3 NOTCH4

4.91e-111227410SM00179
DomainEGF_CA

NID2 FBN1 HMCN2 MEGF6 CD248 CUBN LTBP4 NOTCH3 NOTCH4

5.25e-1186749PF07645
DomainEGF_Ca-bd_CS

NID2 FBN1 HMCN2 MEGF6 CD248 CUBN LTBP4 NOTCH3 NOTCH4

1.58e-1097749IPR018097
DomainEGF-type_Asp/Asn_hydroxyl_site

NID2 FBN1 HMCN2 MEGF6 CD248 CUBN LTBP4 NOTCH3 NOTCH4

3.52e-10106749IPR000152
DomainEGF

NID2 HGFAC STAB2 MEGF6 CD248 LRP5 CUBN NOTCH3 NOTCH4

1.66e-09126749PF00008
DomainASX_HYDROXYL

NID2 FBN1 HMCN2 MEGF6 CUBN LTBP4 NOTCH3 NOTCH4

5.73e-09100748PS00010
DomainKringle

HGFAC KREMEN1 ROR1 ROR2

5.20e-0717744IPR000001
DomainKringle_CS

HGFAC KREMEN1 ROR1 ROR2

5.20e-0717744IPR018056
DomainKRINGLE_2

HGFAC KREMEN1 ROR1 ROR2

5.20e-0717744PS50070
DomainKringle

HGFAC KREMEN1 ROR1 ROR2

5.20e-0717744PF00051
DomainKRINGLE_1

HGFAC KREMEN1 ROR1 ROR2

5.20e-0717744PS00021
DomainKR

HGFAC KREMEN1 ROR1 ROR2

5.20e-0717744SM00130
DomainhEGF

MEGF6 MEGF11 NOTCH3 NOTCH4

4.33e-0628744PF12661
DomainKringle-like

HGFAC KREMEN1 ROR1 ROR2

7.51e-0632744IPR013806
DomainEGF_Lam

STAB2 MEGF6 LAMA5 MEGF11

1.08e-0535744SM00180
DomainEGF_3

NID2 STAB2 CUBN

1.28e-0512743PF12947
DomainEGF_dom

NID2 STAB2 CUBN

1.28e-0512743IPR024731
DomainLaminin_EGF

STAB2 MEGF6 LAMA5 MEGF11

1.51e-0538744IPR002049
DomainTyr_kinase_rcpt_ROR

ROR1 ROR2

1.55e-052742IPR016247
DomainEMI

MEGF6 SSPOP MEGF11

3.90e-0517743PS51041
DomainCUB

KREMEN1 CUBN CSMD2 NRP1

4.20e-0549744PF00431
DomainCUB

KREMEN1 CUBN CSMD2 NRP1

4.55e-0550744SM00042
Domain-

KREMEN1 CUBN CSMD2 NRP1

5.32e-05527442.60.120.290
DomainCUB

KREMEN1 CUBN CSMD2 NRP1

5.74e-0553744PS01180
DomainCUB_dom

KREMEN1 CUBN CSMD2 NRP1

7.65e-0557744IPR000859
DomainGFP

NID2 HMCN2

9.24e-054742IPR009017
DomainNotch

NOTCH3 NOTCH4

9.24e-054742IPR008297
DomainG2F

NID2 HMCN2

9.24e-054742PF07474
DomainNODP

NOTCH3 NOTCH4

9.24e-054742PF07684
DomainNotch_NODP_dom

NOTCH3 NOTCH4

9.24e-054742IPR011656
DomainNotch_NOD_dom

NOTCH3 NOTCH4

9.24e-054742IPR010660
DomainNOD

NOTCH3 NOTCH4

9.24e-054742PF06816
DomainG2_nidogen/fibulin_G2F

NID2 HMCN2

9.24e-054742IPR006605
DomainNOD

NOTCH3 NOTCH4

9.24e-054742SM01338
DomainNODP

NOTCH3 NOTCH4

9.24e-054742SM01339
DomainNIDOGEN_G2

NID2 HMCN2

9.24e-054742PS50993
DomainEGF_extracell

STAB2 MEGF6 MEGF11 NOTCH3

9.36e-0560744IPR013111
DomainEGF_2

STAB2 MEGF6 MEGF11 NOTCH3

9.36e-0560744PF07974
DomainFrizzled_dom

FZD1 ROR1 ROR2

1.14e-0424743IPR020067
DomainFZ

FZD1 ROR1 ROR2

1.14e-0424743PS50038
DomainFz

FZD1 ROR1 ROR2

1.14e-0424743PF01392
DomainFYrich_C

KMT2C KMT2D

1.54e-045742IPR003889
DomainFYrich_N

KMT2C KMT2D

1.54e-045742IPR003888
DomainFYRC

KMT2C KMT2D

1.54e-045742SM00542
DomainFYRN

KMT2C KMT2D

1.54e-045742SM00541
DomainLNR

NOTCH3 NOTCH4

1.54e-045742PS50258
DomainFYRN

KMT2C KMT2D

1.54e-045742PF05964
DomainFYRC

KMT2C KMT2D

1.54e-045742PF05965
DomainFYRC

KMT2C KMT2D

1.54e-045742PS51543
DomainFYRN

KMT2C KMT2D

1.54e-045742PS51542
DomainTB

FBN1 LTBP4

3.21e-047742PF00683
DomainNotch_dom

NOTCH3 NOTCH4

3.21e-047742IPR000800
DomainNotch

NOTCH3 NOTCH4

3.21e-047742PF00066
DomainNL

NOTCH3 NOTCH4

3.21e-047742SM00004
DomainLaminin_EGF

MEGF6 LAMA5 MEGF11

3.57e-0435743PF00053
Domain-

FBN1 LTBP4

4.27e-0487423.90.290.10
DomainGalactose-bd-like

LAMA5 SSPOP EPHA1 NRP1

5.29e-0494744IPR008979
DomainTB

FBN1 LTBP4

5.48e-049742PS51364
DomainTB_dom

FBN1 LTBP4

5.48e-049742IPR017878
DomainSET

KMT2C KMT2D SETD5

5.71e-0441743PF00856
DomainSET

KMT2C KMT2D SETD5

8.02e-0446743SM00317
Domain-

NID2 STAB2

8.32e-04117422.40.155.10
DomainGFP-like

NID2 STAB2

8.32e-0411742IPR023413
DomainTIL

FCGBP SSPOP

9.96e-0412742PF01826
DomainC8

FCGBP SSPOP

9.96e-0412742PF08742
DomainSET_dom

KMT2C KMT2D SETD5

1.02e-0350743IPR001214
DomainSET

KMT2C KMT2D SETD5

1.02e-0350743PS50280
DomainUnchr_dom_Cys-rich

FCGBP SSPOP

1.17e-0313742IPR014853
DomainC8

FCGBP SSPOP

1.17e-0313742SM00832
DomainTIL_dom

FCGBP SSPOP

1.37e-0314742IPR002919
DomainLdl_recept_b

NID2 LRP5

1.37e-0314742PF00058
DomainLDLRB

NID2 LRP5

1.37e-0314742PS51120
DomainSUSHI

CD248 C4BPB CSMD2

1.42e-0356743PS50923
DomainSushi_SCR_CCP_dom

CD248 C4BPB CSMD2

1.50e-0357743IPR000436
DomainLY

NID2 LRP5

1.57e-0315742SM00135
DomainLDLR_classB_rpt

NID2 LRP5

1.57e-0315742IPR000033
DomainPost-SET_dom

KMT2C KMT2D

1.79e-0316742IPR003616
DomainVWD

FCGBP SSPOP

1.79e-0316742SM00216
DomainEMI_domain

MEGF6 MEGF11

1.79e-0316742IPR011489
DomainPostSET

KMT2C KMT2D

1.79e-0316742SM00508
DomainSulfatase_CS

GALNS ARSD

1.79e-0316742IPR024607
DomainVWF_type-D

FCGBP SSPOP

1.79e-0316742IPR001846
DomainVWFD

FCGBP SSPOP

1.79e-0316742PS51233
DomainPOST_SET

KMT2C KMT2D

1.79e-0316742PS50868
DomainVWD

FCGBP SSPOP

1.79e-0316742PF00094
DomainSULFATASE_1

GALNS ARSD

2.03e-0317742PS00523
DomainSULFATASE_2

GALNS ARSD

2.03e-0317742PS00149
DomainSulfatase

GALNS ARSD

2.27e-0318742PF00884
DomainSulfatase_N

GALNS ARSD

2.27e-0318742IPR000917
DomainVWC_out

FCGBP SSPOP

2.54e-0319742SM00215
DomainZnf_FYVE_PHD

KMT2C KMT2D MTMR3 PHF21B

2.77e-03147744IPR011011
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

ELF3 NOTCH3 NOTCH4

2.17e-067573MM14734
PathwayPID_WNT_SIGNALING_PATHWAY

FZD1 KREMEN1 ROR2 LRP5

4.57e-0628574M77
PathwayWP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA

FZD1 KREMEN1 ROR1 ROR2 LRP5

2.90e-0589575M39563
PathwayKEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY

FZD1 ROR1 ROR2

3.38e-0516573M47823
PathwayWP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER

FZD1 KREMEN1 ROR1 ROR2 LRP5

4.61e-0598575M39731
PathwayWP_WNT_SIGNALING_WP428

FZD1 KREMEN1 ROR1 ROR2 LRP5

9.10e-05113575M39669
PathwayPID_INTEGRIN1_PATHWAY

FBN1 ITGA10 LAMA5 PLAUR

1.44e-0466574M18
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH3 NOTCH4

1.59e-045572M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH3 NOTCH4

1.59e-045572MM14733
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS2 SSPOP NOTCH3 NOTCH4

1.61e-0468574M27303
PathwayREACTOME_SIGNALING_BY_LRP5_MUTANTS

KREMEN1 LRP5

2.38e-046572M27432
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH3 NOTCH4

2.38e-046572M27068
PathwayWP_HAIR_FOLLICLE_DEVELOPMENT_ORGANOGENESIS_STAGE_2_OF_3

FZD1 LAMA5 LRP5

2.86e-0432573M40041
PathwayWP_TYPE_I_COLLAGEN_SYNTHESIS_IN_THE_CONTEXT_OF_OSTEOGENESIS_IMPERFECTA

FZD1 ADAMTS2 LRP5

3.14e-0433573M39870
PathwayWP_PLEURAL_MESOTHELIOMA

FZD1 KMT2C KREMEN1 SETD5 ROR1 ROR2 LAMA5 LRP5

3.59e-04439578M42563
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

FBN1 LTBP4

4.43e-048572M47850
PathwayREACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_WNT_LIGAND_ANTAGONISTS

KREMEN1 LRP5

4.43e-048572MM14976
PathwayREACTOME_DISEASES_OF_METABOLISM

GALNS ADAMTS2 CUBN SSPOP NOTCH3 NOTCH4

4.99e-04250576M27554
PathwayREACTOME_SIGNALING_BY_NOTCH

ELF3 NOTCH3 NOTCH4

5.17e-0439573MM14604
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

FBN1 USP9X USP15 LTBP4

5.59e-0494574M1041
PathwayREACTOME_CHL1_INTERACTIONS

ITGA10 NRP1

5.68e-049572M27379
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

NID2 FBN1 MEGF6 ADAMTS2 ITGA10 LTBP4

5.89e-04258576MM14572
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH3 NOTCH4

8.63e-0411572M47865
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

FBN1 USP15 LTBP4

8.96e-0447573M646
PathwayWP_CANCER_PATHWAYS

FZD1 EGLN3 LAMA5 LRP5 NOS2 ADCY5 NOTCH3 NOTCH4

9.28e-04507578M48302
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH3 NOTCH4

1.03e-0312572M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH3 NOTCH4

1.03e-0312572M47533
PathwayWP_WNT_SIGNALING_WP363

ROR1 ROR2 LRP5

1.14e-0351573M39721
PathwayREACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2

ROR1 ROR2

1.22e-0313572M27415
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH3 NOTCH4

1.22e-0313572M47423
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH3 NOTCH4

1.22e-0313572M47534
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

NID2 FBN1 ADAMTS2 ITGA10 LAMA5 LTBP4

1.29e-03300576M610
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

FZD1 LRP5 NOTCH3 NOTCH4

1.31e-03118574M39852
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4

FZD1 LRP5

1.42e-0314572M47834
PathwayREACTOME_LAMININ_INTERACTIONS

NID2 MEGF6

1.63e-0315572MM14922
PathwayREACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_WNT_LIGAND_ANTAGONISTS

KREMEN1 LRP5

1.63e-0315572M27273
PathwayPID_NOTCH_PATHWAY

SSPOP NOTCH3 NOTCH4

1.74e-0359573M17
PathwayREACTOME_SIGNALING_BY_WNT

FZD1 KMT2D KREMEN1 ROR1 ROR2 LRP5

2.09e-03330576M7847
PathwayPID_INTEGRIN5_PATHWAY

FBN1 PLAUR

2.10e-0317572M212
PathwayWP_HISTONE_MODIFICATIONS

KMT2C KMT2D SETD5

2.29e-0365573M39374
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH3 NOTCH4

2.36e-0318572M614
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS2 SSPOP NOTCH3 NOTCH4

2.64e-03143574M27275
PathwayREACTOME_SIGNALING_BY_WNT

FZD1 KMT2D KREMEN1 ROR1 LRP5

2.74e-03239575MM14756
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

LAMA5 LRP5 PLAUR

3.07e-0372573M39403
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

LAMA5 LRP5 PLAUR

3.19e-0373573MM15906
Pubmed

A high-resolution molecular atlas of the fetal mouse lower urogenital tract.

KREMEN1 ROR1 ROR2 ETV1 LRP5 ELF3

1.47e-087575621905163
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RANBP17 TRPM4 KMT2C MEGF6 SETD5 C11orf54 TSPAN10 ZNF587 ROR2 ETV1 LRP5 TMPRSS5 USP15 SSPOP NOTCH3 NRP1

9.22e-081489751628611215
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

NID2 FBN1 HMCN2 MEGF6 LAMA5 LTBP4 SSPOP

1.08e-0717575728071719
Pubmed

Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis.

FZD1 ROR2 NOTCH4

1.14e-061075317496152
Pubmed

Congenital Diaphragmatic Hernia Overview

ARID1B KMT2D FBN1 LTBP4

3.04e-064675420301533
Pubmed

ROR1 and ROR2 expression in pancreatic cancer.

ROR1 ROR2

4.59e-06275234763666
Pubmed

Transcriptomic data showing differentially expressed genes between Notch3 and Notch4 deleted mice.

NOTCH3 NOTCH4

4.59e-06275233665264
Pubmed

Aberrant Notch3 and Notch4 expression in human hepatocellular carcinoma.

NOTCH3 NOTCH4

4.59e-06275217696940
Pubmed

KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.

KMT2C KMT2D

4.59e-06275231924266
Pubmed

Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases.

ROR1 ROR2

4.59e-06275211713269
Pubmed

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.

KMT2C KMT2D

4.59e-06275228967912
Pubmed

The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation.

ROR1 ROR2

4.59e-06275234155901
Pubmed

Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies.

ROR1 ROR2

4.59e-06275222988987
Pubmed

Stabilization of PTGES by deubiquitinase USP9X promotes metastatic features of lung cancer via PGE2 signaling.

USP9X PTGES

4.59e-06275231285948
Pubmed

A genetic determinant that specifically regulates the frequency of hematopoietic stem cells.

NOTCH3 NOTCH4

4.59e-06275211777956
Pubmed

Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression.

ROR1 ROR2

4.59e-06275237430307
Pubmed

Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system.

ROR1 ROR2

4.59e-06275210231392
Pubmed

Role of the Ror family receptors in Wnt5a signaling.

ROR1 ROR2

4.59e-06275238587578
Pubmed

Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.

KMT2C KMT2D

4.59e-06275236601880
Pubmed

Expression and subcellular localization of Ror tyrosine kinase receptors are developmentally regulated in cultured hippocampal neurons.

ROR1 ROR2

4.59e-06275212898527
Pubmed

Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.

KMT2C KMT2D

4.59e-06275228483418
Pubmed

Expression of the receptor tyrosine kinase genes, Ror1 and Ror2, during mouse development.

ROR1 ROR2

4.59e-06275211429290
Pubmed

Shunting of prostanoid biosynthesis in microsomal prostaglandin E synthase-1 null embryo fibroblasts: regulatory effects on inducible nitric oxide synthase expression and nitrite synthesis.

PTGES NOS2

4.59e-06275217023389
Pubmed

The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.

KMT2C KMT2D

4.59e-06275234156443
Pubmed

A novel family of cell surface receptors with tyrosine kinase-like domain.

ROR1 ROR2

4.59e-0627521334494
Pubmed

Neurite extension in central neurons: a novel role for the receptor tyrosine kinases Ror1 and Ror2.

ROR1 ROR2

4.59e-06275215654020
Pubmed

Evolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains.

ROR1 ROR2

4.59e-06275225029443
Pubmed

Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome.

FBN1 NOTCH3

4.59e-06275232616814
Pubmed

Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.

KMT2C KMT2D

4.59e-06275227280393
Pubmed

Expression of the Ror1 and Ror2 receptor tyrosine kinase genes during mouse development.

ROR1 ROR2

4.59e-06275211455430
Pubmed

Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice.

NOTCH3 NOTCH4

4.59e-06275225658374
Pubmed

Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion.

ROR1 ROR2

4.59e-06275226515598
Pubmed

Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.

KMT2C KMT2D

4.59e-06275236869380
Pubmed

β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases.

ROR1 ROR2

4.59e-06275226862065
Pubmed

ROR1 and ROR2 play distinct and opposing roles in endometrial cancer.

ROR1 ROR2

4.59e-06275229395309
Pubmed

Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.

KMT2C KMT2D

4.59e-06275225346535
Pubmed

Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.

ROR1 ROR2

4.59e-06275224104062
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

FZD1 TMPRSS5 CUBN EPHA1 NRP1

5.65e-0611775517145500
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

NOTCH3 NOTCH4 NRP1

7.68e-061875318093989
Pubmed

GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.

ADGRA3 NOTCH3 NOTCH4 NRP1

8.30e-065975421421844
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

GLIPR1 FBN1 GALNS ROR2 PTGES LAMA5 LRP5 PLAUR USP15 ADGRA3 NOTCH3 NRP1

9.55e-061201751235696571
Pubmed

USP9X promotes apoptosis in cholangiocarcinoma by modulation expression of KIF1Bβ via deubiquitinating EGLN3.

EGLN3 USP9X

1.37e-05375234112167
Pubmed

Notch receptor expression in human brain arteriovenous malformations.

NOTCH3 NOTCH4

1.37e-05375225846406
Pubmed

Ror1-Ror2 complexes modulate synapse formation in hippocampal neurons.

ROR1 ROR2

1.37e-05375219958813
Pubmed

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

KMT2C KMT2D

1.37e-05375223932714
Pubmed

Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.

KMT2C KMT2D

1.37e-05375222183980
Pubmed

Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation.

ROR1 ROR2

1.37e-05375226690702
Pubmed

Mice carrying a R142C Notch 3 knock-in mutation do not develop a CADASIL-like phenotype.

NOTCH3 NOTCH4

1.37e-05375215645445
Pubmed

HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.

KMT2C KMT2D

1.37e-05375221683083
Pubmed

Linking of mPGES-1 and iNOS activates stem-like phenotype in EGFR-driven epithelial tumor cells.

PTGES NOS2

1.37e-05375228257996
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

NID2 FBN1 HMCN2 LAMA5 LTBP4

1.66e-0514675527068509
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

FBN1 LAMA5 NOTCH3

2.42e-052675334189436
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FZD1 TRPM4 KMT2C KMT2D MEGF6 SETD5 ZNF516 MTMR3 LAMA5 LRP5 LTBP4

2.42e-051105751135748872
Pubmed

Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.

KMT2C KMT2D

2.75e-05475219221051
Pubmed

Cancer gene mutation frequencies for the U.S. population.

KMT2C KMT2D

2.75e-05475234645806
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH3 NOTCH4

2.75e-05475224145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH3 NOTCH4

2.75e-05475220069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH3 NOTCH4

2.75e-05475219404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH3 NOTCH4

2.75e-05475228669409
Pubmed

Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis.

KREMEN1 LRP5

2.75e-05475223041840
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH3 NOTCH4

2.75e-05475211401408
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH3 NOTCH4

2.75e-0547528898100
Pubmed

Protein Kinase Cι Drives a NOTCH3-dependent Stem-like Phenotype in Mutant KRAS Lung Adenocarcinoma.

ELF3 NOTCH3

2.75e-05475226977885
Pubmed

Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism.

KREMEN1 LRP5

2.75e-05475218502762
Pubmed

Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates.

ROR1 ROR2

2.75e-05475228885975
Pubmed

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice.

FZD1 LRP5

2.75e-05475231452509
Pubmed

Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome.

FBN1 NOS2

2.75e-05475228067899
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH3 NOTCH4

2.75e-05475223444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH3 NOTCH4

2.75e-05475217920003
Pubmed

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

FBN1 LTBP4

2.75e-05475212429738
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH3 NOTCH4

2.75e-05475228061457
Pubmed

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.

KMT2C KMT2D

2.75e-05475228398509
Pubmed

Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2.

NID2 HMCN2

2.75e-05475236007682
Pubmed

Protocadherin-17 mediates collective axon extension by recruiting actin regulator complexes to interaxonal contacts.

PCDH17 NRP1

2.75e-05475225199687
Pubmed

The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates its intracellular distribution.

ROR1 ROR2

2.75e-05475212754255
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH3 NOTCH4

2.75e-05475211466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH3 NOTCH4

2.75e-05475224151014
Pubmed

A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.

KMT2C KMT2D

2.75e-05475223129768
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH3 NOTCH4

2.75e-05475210194420
Pubmed

Essential role of Wnt5a-Ror1/Ror2 signaling in metanephric mesenchyme and ureteric bud formation.

ROR1 ROR2

2.75e-05475226840931
Pubmed

Differential expression of DKK-1 binding receptors on stromal cells and myeloma cells results in their distinct response to secreted DKK-1 in myeloma.

KREMEN1 LRP5

2.75e-05475220846389
Pubmed

Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow.

FZD1 LRP5

2.75e-05475211433302
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH3 NOTCH4

2.75e-05475211459941
Pubmed

MicroRNA-183 suppresses cancer stem-like cell properties in EBV-associated nasopharyngeal carcinoma.

NOTCH3 NOTCH4

2.75e-05475227431799
Pubmed

The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.

KMT2C KMT2D

2.75e-05475224081332
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH3 NOTCH4

2.75e-05475218184405
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH3 NOTCH4

2.75e-05475215917835
Pubmed

Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.

NUDT6 NOTCH3 NRP1

3.75e-053075319054571
Pubmed

Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.

KMT2C KMT2D

4.57e-05575231127101
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH3 NOTCH4

4.57e-05575211101851
Pubmed

Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.

NOTCH3 NOTCH4

4.57e-05575220554499
Pubmed

Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.

NOTCH3 NOTCH4

4.57e-05575221726900
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH3 NOTCH4

4.57e-05575221124806
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH3 NOTCH4

4.57e-05575223675950
Pubmed

Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells.

NOTCH3 NOTCH4

4.57e-05575221602525
Pubmed

Appropriate crypt formation in the uterus for embryo homing and implantation requires Wnt5a-ROR signaling.

ROR1 ROR2

4.57e-05575225043182
Pubmed

MLL3/MLL4-Associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBPβ and C/EBPδ.

KMT2C KMT2D

4.57e-05575232601106
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH3 NOTCH4

4.57e-05575215882997
Pubmed

A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex.

KMT2C KMT2D

4.57e-05575226744420
Pubmed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

NID2 FBN1 LAMA5 LTBP4

5.94e-059775427559042
InteractionMFAP5 interactions

FBN1 MEGF6 LAMA5 LTBP4 NOTCH3

1.41e-0652755int:MFAP5
InteractionSLURP1 interactions

NID2 ADAMTS2 ROR2 LAMA5 EPHA1 DDX11

1.61e-05144756int:SLURP1
InteractionGSC interactions

KMT2C ARID1B KMT2D TBX21 ZNF516

1.82e-0587755int:GSC
InteractionWNT1 interactions

FZD1 ROR2 LRP5

2.68e-0516753int:WNT1
InteractionNOTCH2 interactions

EGLN3 ROR1 ROR2 PLAUR ZNF417 LTBP4 ZNF783 NOTCH3 NOTCH4

2.68e-05423759int:NOTCH2
InteractionODAPH interactions

FBN1 LAMA5 LRP5 LTBP4

3.30e-0549754int:ODAPH
InteractionSUSD4 interactions

NID2 ADAMTS2 LAMA5 LRP5

3.58e-0550754int:SUSD4
InteractionHOXA1 interactions

FBN1 MEGF6 TRIP6 ZNF587 LAMA5 ZNF417 LTBP4 NOTCH3

5.28e-05356758int:HOXA1
InteractionMAML3 interactions

NID2 NOTCH3 NOTCH4

5.39e-0520753int:MAML3
InteractionATN1 interactions

KMT2C MEGF6 TRIP6 LTBP4 SSPOP MEGF11

6.97e-05187756int:ATN1
InteractionNTN5 interactions

FBN1 LTBP4 NOTCH3

9.47e-0524753int:NTN5
InteractionFZD10 interactions

TSPAN15 LRP5 ATP2B2 NRP1

1.07e-0466754int:FZD10
InteractionTAFAZZIN interactions

NID2 GALNS ADAMTS2 LRP5 PLAUR USP15

1.22e-04207756int:TAFAZZIN
InteractionFBXO2 interactions

NID2 FBN1 LAMA5 C4BPB LTBP4 ADGRA3 NOTCH3 EPHA1

1.43e-04411758int:FBXO2
Cytoband7q36.1

KMT2C SSPOP ZNF783

2.50e-04747537q36.1
GeneFamilySulfatases

GALNS ARSD

1.30e-0318542410
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HMCN2 ROR1 ROR2 ADGRA3

1.35e-03161544593
GeneFamilyPHD finger proteins

KMT2C KMT2D PHF21B

2.46e-039054388
GeneFamilyETS transcription factor family

ETV1 ELF3

3.15e-0328542534
GeneFamilyTransient receptor potential cation channels

TRPM4 TRPA1

3.15e-0328542249
GeneFamilyCD molecules|Tetraspanins

TSPAN15 TSPAN10

4.36e-0333542768
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2C KMT2D

4.62e-0334542487
GeneFamilyReceptor Tyrosine Kinases|CD molecules

ROR1 ROR2

6.35e-0340542321
CoexpressionREN_ALVEOLAR_RHABDOMYOSARCOMA_DN

FZD1 GLIPR1 FBN1 CD248 ADAMTS2 PTGES ELF3 PLAUR NRP1

2.44e-06407759M19541
CoexpressionNABA_ECM_GLYCOPROTEINS

NID2 FBN1 HMCN2 LAMA5 LTBP4 SSPOP

1.84e-05191756MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

NID2 FBN1 HMCN2 LAMA5 LTBP4 SSPOP

2.12e-05196756M3008
CoexpressionMURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL

NID2 ZNF469 FBN1 CD248 ADAMTS2 NHSL2 PTGES PLAUR NOTCH3 NRP1

2.38e-056817510M39175
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FZD1 NID2 CD248 ADAMTS2 PTGES RGS3 ADCY5

2.99e-08187757f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FZD1 NID2 CD248 ADAMTS2 PTGES RGS3 ADCY5

2.99e-0818775702e7246ef5ad41773d14426254e139b156d45c1d
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FZD1 NID2 CD248 ADAMTS2 PTGES RGS3 ADCY5

2.99e-0818775708c73d125e0638c9e9878165bba2442c266c8a48
ToppCell(6)_Endothelial-C_(Capillary_Aerocyte_)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

TSPAN15 ITGA10 LAMA5 NOS2 PCDH17 NOTCH4 DDX11

3.72e-08193757f7f2dc6aff02d096a282835094d26d12b3b73e61
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NID2 ZNF469 FBN1 CD248 ADAMTS2 ROR1 ROR2

4.58e-0819975721335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCellClub_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

FCGBP PTGES ELF3 ADGRA3 NOTCH3 DDX11

5.66e-07178756be64d4be23fb96a4cdd7980c58880fdfe817747f
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ZNF469 FBN1 HMCN2 CD248 ADAMTS2 LTBP4

6.44e-07182756e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TSPAN15 ETV1 NOS2 PCDH17 NOTCH4 NRP1

6.44e-07182756997d37ca2af661c92a56add888762724dfccc890
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|normal_Lung / Location, Cell class and cell subclass

ZNF469 FBN1 HMCN2 CD248 ADAMTS2 ROR2

6.87e-071847560b336489c10e8c3c957795dd845454f03404382b
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2|TCGA-Kidney / Sample_Type by Project: Shred V9

NID2 FBN1 CD248 ADAMTS2 PCDH17 NOTCH3

7.32e-071867561e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRPM4 EGLN3 FCGBP PTGES LRP5 ELF3

7.55e-0718775671d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 FBN1 HMCN2 MEGF6 ROR2 LTBP4

8.28e-07190756efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TSPAN15 EGLN3 ITGA10 NOS2 PCDH17 NOTCH4

8.54e-071917561de0bdfd13bd930691564c2673f2e66393bc0255
ToppCell10x5'v1-week_12-13-Endothelial-stroma-tip_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FBN1 LAMA5 NOS2 PCDH17 NOTCH4 NRP1

8.54e-07191756cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 FBN1 ADAMTS2 ROR1 ROR2 LTBP4

8.54e-0719175639092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 FBN1 ADAMTS2 ROR1 ROR2 LTBP4

8.54e-07191756ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NID2 FBN1 CD248 ROR2 LTBP4 PHF21B

8.80e-07192756b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FZD1 CD248 ADAMTS2 PTGES ADCY5 NOTCH3

9.08e-07193756cf2461af78f65616ce40d552ee9452295e3895ed
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FZD1 CD248 ADAMTS2 PTGES ADCY5 NOTCH3

9.08e-071937566ef9007c9d18fb775d08fb20cdf954a28d54d7eb
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FZD1 CD248 ADAMTS2 PTGES ADCY5 NOTCH3

9.08e-07193756e4ea7ce011a80b81b841c907719aa532bed39d2e
ToppCellPCW_07-8.5-Mesenchymal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FZD1 FBN1 CD248 ROR1 ROR2 LTBP4

9.93e-071967568e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 FBN1 CD248 ADAMTS2 ROR1 LTBP4

9.93e-07196756b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 FBN1 CD248 ADAMTS2 ROR1 LTBP4

9.93e-07196756787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

EGLN3 FBN1 CUBN LTBP4 ATP2B2 NOTCH4

1.02e-06197756ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FZD1 FBN1 ROR1 ROR2 ETV1 LTBP4

1.02e-0619775673a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellPND14-Mesenchymal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD1 FBN1 CD248 ADAMTS2 ETV1 LTBP4

1.02e-061977569a14bc2e7d6081e2ab0e2e5555fc8804f13d3dbe
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD1 FBN1 CD248 ADAMTS2 ETV1 NOTCH3

1.02e-061977568c728cd3c0382c4f3e4b78647b6e1447bb40ace1
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NID2 ZNF469 FBN1 MEGF6 PTGES NRP1

1.05e-061987569541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCell15-Airway-Mesenchymal-Mesenchyme_SERPINF1-high|Airway / Age, Tissue, Lineage and Cell class

FBN1 CD248 ADAMTS2 ROR1 LTBP4 NRP1

1.05e-061987563d76393e72eed59b4dd16130ef5dd1d331ba5711
ToppCell10x5'v1-week_12-13-Endothelial-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TSPAN15 STAB2 LAMA5 PCDH17 NOTCH4 NRP1

1.05e-06198756122215d9288533ad03562cf777e846504863df9a
ToppCell10x5'v1-week_12-13-Endothelial|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TSPAN15 STAB2 LAMA5 PCDH17 NOTCH4 NRP1

1.05e-06198756307dd09e6bc820a148f3000f18dae7aedba4be0b
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

NID2 FBN1 ADAMTS2 ROR2 LTBP4 ADCY5

1.05e-06198756bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FZD1 FBN1 CD248 ADAMTS2 PTGES NOTCH3

1.08e-061997569b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FZD1 FBN1 CD248 ADAMTS2 PTGES NOTCH3

1.08e-06199756251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TSPAN15 ITGA10 LAMA5 PCDH17 NOTCH4 NRP1

1.08e-061997561621ce2968f3100e4c39e0ef8293232a5d76c614
ToppCellPCW_10-12-Mesenchymal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FZD1 FBN1 ROR1 ROR2 ETV1 LTBP4

1.08e-06199756a09292de4c4447b8eee55d401808e43b817321cc
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FZD1 FBN1 CD248 ADAMTS2 PTGES NOTCH3

1.08e-06199756117f4f43b6c06dda553799b1063e827bce697370
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TSPAN15 ITGA10 LAMA5 PCDH17 NOTCH4 NRP1

1.12e-062007563653002c805c314043e2a7b0c9980dfe952dc53e
ToppCell10x5'v1-week_14-16-Endothelial-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EGLN3 STAB2 LRP5 PCDH17 NOTCH4 NRP1

1.12e-062007562488aa12970a43a5af352e2c36c73884d73a1cc5
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD1 FBN1 CD248 ADAMTS2 ROR2 LTBP4

1.12e-062007563dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCell10x5'v1-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EGLN3 STAB2 LRP5 PCDH17 NOTCH4 NRP1

1.12e-06200756ae429f2de652cc1976e63644781197e9ce0e70c8
ToppCell10x5'v1-week_14-16-Endothelial|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EGLN3 STAB2 LRP5 PCDH17 NOTCH4 NRP1

1.12e-06200756e786544cf6f891550c4be55ebb4928c92297b504
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD1 FBN1 CD248 ADAMTS2 ROR2 LTBP4

1.12e-06200756ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCellICU-SEP-Myeloid-cDC1|ICU-SEP / Disease, Lineage and Cell Type

TSPAN15 EGLN3 TRIP6 LAMA5 ADGRA3

7.77e-061617559fb73909fc2ec99f96ca2eed1a053bce89de7d16
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN1 TRPA1 KREMEN1 ETV1 ITGA10

8.50e-06164755a764b79a127c8f360af0b79a1da64658badf0dfa
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|368C / Donor, Lineage, Cell class and subclass (all cells)

EGLN3 LAMA5 NOS2 PCDH17 NOTCH4

9.02e-0616675530a991fc3275b571d53bd0976df4789e5d40b01d
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|368C / Donor, Lineage, Cell class and subclass (all cells)

EGLN3 LAMA5 NOS2 PCDH17 NOTCH4

9.02e-0616675576b4cd32698900797ec009f17e50ea7ae36b85f4
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EGLN3 STAB2 MEGF6 LTBP4 ATP2B2

9.28e-06167755f01b96173deda0239fa482989873cf308e49d48c
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EGLN3 STAB2 MEGF6 LTBP4 ATP2B2

9.28e-061677555fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

NID2 ZNF469 FBN1 CD248 ADAMTS2

9.56e-06168755aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellAdult-Mesenchymal-chondrocyte-D175|Adult / Lineage, Cell type, age group and donor

HMCN2 NHSL2 ZNF587 ROR1 NOTCH4

9.56e-0616875514071b961c9bdb54a8259b12a88237b802cbde36
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN15 ROR1 SSPOP ADCY5 NOTCH3

1.10e-05173755d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN15 ROR1 SSPOP ADCY5 NOTCH3

1.10e-051737553c852ffe22f4a5b632463086b08c669310684e80
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HGFAC LAMA5 TMPRSS5 ELF3 NOTCH3

1.13e-05174755207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FZD1 FBN1 ROR2 ITGA10 LTBP4

1.16e-051757551799a7be623dc3bf53ba580a7c47d2619969d708
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 EGLN3 FCGBP KREMEN1 EPHA1

1.16e-0517575531f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN1 MEGF6 ADAMTS2 LTBP4 NOTCH3

1.26e-051787559fc5688cf705a74398d24e10e0aab4758612e72b
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

FZD1 ZNF469 FBN1 ADAMTS2 ETV1

1.26e-05178755142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CD248 ITGA10 PHF21B NOTCH3 NRP1

1.30e-0517975598c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBN1 HMCN2 CD248 ADAMTS2 LTBP4

1.33e-051807559adebde5f4ca6dcb90e9113622862e14298465ac
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF469 FBN1 HMCN2 ADAMTS2 LTBP4

1.37e-051817553462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCellMesenchymal_cells-Stromal_fibro.|Mesenchymal_cells / Lineage and Cell class

ROR2 PTGES ETV1 LTBP4 ADCY5

1.37e-05181755f8d914fdc06aaa75a4dc9158daf574ca28fa5432
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

TSPAN15 LAMA5 NOS2 PCDH17 NOTCH4

1.37e-05181755c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF469 FBN1 HMCN2 ADAMTS2 LTBP4

1.37e-051817556730e249cac55ae892cc567d9211615882f3dab4
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC FCGBP PER3 ETV1 C4BPB

1.37e-0518175575340f0c06977c88f9d2e56265f4aa84d706d2c6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 CD248 ADAMTS2 LTBP4 NRP1

1.41e-05182755b7d532feb73167e05475855061b35a209583f44c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 CD248 ADAMTS2 LTBP4 NRP1

1.41e-05182755af65f0fc3f9e5d9ce69ee5faaf5b6cb7f8412e0c
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 MEGF6 LAMA5 LTBP4 ATP2B2

1.48e-05184755f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 MEGF6 LAMA5 LTBP4 ATP2B2

1.48e-051847558bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN15 LTBP4 NOS2 NOTCH4 NRP1

1.52e-0518575562cfcb0e2a9e6718e6b200dfbb1a81eaead229b5
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

FBN1 HMCN2 CD248 ADAMTS2 ROR2

1.52e-05185755fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell(2)_Fibroblasts-(20)_Fibro-1|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

FBN1 HMCN2 CD248 LTBP4 NRP1

1.56e-05186755e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_naive-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KREMEN1 ADAMTS2 NHSL2 PLAUR NOTCH3

1.60e-051877553b1439018e265a61d9599e307a202e3c2f60ed32
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_naive|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KREMEN1 ADAMTS2 NHSL2 PLAUR NOTCH3

1.60e-05187755e99bc27d212c74da37770297122a4b30445ccd0d
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN15 PER3 ELF3 KLHDC7A EPHA1

1.60e-05187755aa336fb568a24e12c0454265ddd71ed10a6614cf
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

KREMEN1 ADAMTS2 NHSL2 ROR2 NRP1

1.60e-05187755e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellP15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MEGF6 NHSL2 LTBP4 RGS3 NOTCH4

1.64e-0518875550b27fc12347ca16bd62333baf345c83cb422a8f
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NID2 FBN1 CD248 ADAMTS2 LTBP4

1.64e-051887556c6486cae9a8f2f8200598cb4bfd3fd513eb28a3
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 LTBP4 ATP2B2 NOTCH3 NOTCH4

1.64e-05188755ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic|GI_large-bowel / Manually curated celltypes from each tissue

FZD1 FCGBP ADAMTS2 ZNF516 NRP1

1.64e-05188755d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 FBN1 HMCN2 MEGF6 LTBP4

1.64e-05188755ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes|GI_large-bowel / Manually curated celltypes from each tissue

FZD1 FCGBP ADAMTS2 ZNF516 NRP1

1.64e-051887550bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ITGA10 LAMA5 NOS2 PCDH17 NOTCH4

1.64e-05188755fe7143c36e4a883745862d3c3147cf751b440e46
ToppCelldroplet-Fat-SCAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN15 LAMA5 PCDH17 NOTCH3 NRP1

1.64e-051887555cf060bb8adaefa9964187195d67993c1248ef47
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPA1 KREMEN1 ITGA10 LAMA5 CSMD2

1.64e-05188755997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NHSL2 LAMA5 PCDH17 NOTCH4 NRP1

1.64e-05188755a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|343B / Donor, Lineage, Cell class and subclass (all cells)

ITGA10 LAMA5 NOS2 PCDH17 NOTCH4

1.64e-05188755cbf32b675a7cd0c808d5c9c22dfa7fa79fbe2437
ToppCelldroplet-Fat-SCAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN15 LAMA5 PCDH17 NOTCH3 NRP1

1.64e-05188755449f9602df3c83b2110eb479a00d428d1b55b423
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 FBN1 ADAMTS2 ROR2 LTBP4

1.69e-0518975571397e993a77d70b2eeede240bdfc7660b558987
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 PER3 ADAMTS2 PTGES LTBP4

1.69e-0518975532e6d6285b258831b965281224ff2aaeecdcb5f5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 FBN1 ADAMTS2 ROR2 LTBP4

1.69e-051897554eea4759520c312bd17a681034d8074e47093d2b
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN15 LTBP4 PCDH17 NOTCH4 NRP1

1.69e-051897558ced0381ea042ba47680a02b617a2368fa2c54c8
ToppCellLAM-Endothelial-VasEndo-1|LAM / Condition, Lineage and Cell class

TSPAN15 ITGA10 PCDH17 NOTCH4 NRP1

1.69e-05189755454e64b1ee93edebbc1576fbf7c3a6db332fa927
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN15 LTBP4 PCDH17 NOTCH4 NRP1

1.69e-05189755403a82bb416aed13b9d31411ad17bdc4ce2a95fb
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 PER3 ADAMTS2 PTGES LTBP4

1.69e-05189755385ef7bbd76c8047aeecf6542377d4213b5da5db
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP PTGES ELF3 KLHDC7A NOTCH3

1.69e-0518975527e5d706f10a6221f314faf642eede15deab3165
ToppCelldroplet-Fat-Scat-21m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN15 LTBP4 PCDH17 NOTCH4 NRP1

1.73e-05190755d3e46cf800a07ca9b01c78192962d223b9785d05
ToppCelldroplet-Fat-Scat-21m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN15 LTBP4 PCDH17 NOTCH4 NRP1

1.73e-05190755dd89ef1ecea20b2f6fbdc6cea4ca41b28b3ed822
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEGF6 ADAMTS2 ITGA10 ADCY5 NOTCH3

1.73e-051907557df63e5e0dd395676f4fc18cad0d8b2428390943
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 ADAMTS2 ROR1 ROR2 NOTCH3

1.73e-0519075570c86dd454afb21d4a85db56c5f369d4b342bc97
DrugSpiperone [749-02-0]; Down 200; 10.2uM; PC3; HT_HG-U133A

TSPAN15 NUDT6 ITGA10 LRP5 RGS3 NOTCH3 EPHA1

2.69e-061867575777_DN
DrugEsculin Hydrate [531-75-9]; Up 200; 11.8uM; HL60; HT_HG-U133A

EGLN3 CD248 ACSBG1 PTGES ETV1 PCDH17 NRP1

4.21e-061997573052_UP
DiseaseInflammation

GALNS TRPA1 TBX21 PTGES PLAUR NOS2

6.99e-07127726C0021368
Diseasehair colour measurement

FZD1 ZNF469 KMT2D GALNS KREMEN1 TSPAN10 ETV1 LRP5 RGS3 DDX11

2.41e-066157210EFO_0007822
Diseaseurate measurement, bone density

GLIPR1 RANBP17 FEZF1 ZNF516 ETV1 LAMA5 ATP2B2 MEGF11 PCDH17 NOTCH4

2.56e-066197210EFO_0003923, EFO_0004531
Diseasecortical thickness

EGLN3 ZNF469 ARID1B FBN1 ADAMTS2 SETD5 TSPAN10 ROR1 MTMR3 USP15 KIAA1614 PCDH17 NRP1

2.62e-0611137213EFO_0004840
DiseaseKleefstra syndrome 2 (implicated_via_orthology)

KMT2C KMT2D

5.87e-062722DOID:0080598 (implicated_via_orthology)
Diseaseintraocular pressure measurement

EGLN3 ZNF469 FBN1 KREMEN1 ADAMTS2 TSPAN10 ZNF516 ETV1

3.38e-05509728EFO_0004695
DiseaseBreast Carcinoma

ARID1B KMT2D PER3 ROR1 KLHDC7A NOS2 NOTCH3 NOTCH4

4.99e-05538728C0678222
DiseaseMalignant neoplasm of breast

NID2 ARID1B KMT2D PER3 ROR1 MTMR3 KLHDC7A CUBN NOS2 NOTCH3 NOTCH4

5.58e-0510747211C0006142
DiseaseNeurodevelopmental Disorders

KMT2C ARID1B SETD5 ADCY5

8.07e-0593724C1535926
Diseaseasthma (implicated_via_orthology)

TRPA1 TBX21 NOS2

8.62e-0535723DOID:2841 (implicated_via_orthology)
Diseaseplatelet crit

HGFAC NHSL2 ETV1 LAMA5 PLAUR CUBN USP15 KIAA1614 ADCY5 NOTCH3

1.02e-049527210EFO_0007985
DiseaseFEV/FEC ratio

NID2 FBN1 FCGBP KREMEN1 MEGF6 ADAMTS2 TSPAN10 ZNF516 MTMR3 ETV1 LTBP4

1.82e-0412287211EFO_0004713
DiseaseMarfan Syndrome, Type I

FBN1 NOS2

2.09e-049722C4721845
DiseaseMammary Carcinoma, Human

KMT2D PER3 ROR1 KLHDC7A NOS2 NOTCH3 NOTCH4

2.94e-04525727C4704874
DiseaseMammary Neoplasms, Human

KMT2D PER3 ROR1 KLHDC7A NOS2 NOTCH3 NOTCH4

2.94e-04525727C1257931
DiseaseMammary Neoplasms

KMT2D PER3 ROR1 KLHDC7A NOS2 NOTCH3 NOTCH4

3.01e-04527727C1458155
DiseaseMarfan Syndrome

FBN1 NOS2

3.18e-0411722C0024796
Diseaseresponse to lithium ion

MEGF6 CSMD2 NOTCH4

3.52e-0456723GO_0010226
Diseaselung non-small cell carcinoma (is_implicated_in)

KMT2C ARID1B KMT2D NRP1

3.78e-04139724DOID:3908 (is_implicated_in)
Diseasedementia (is_implicated_in)

NOS2 NOTCH4

3.81e-0412722DOID:1307 (is_implicated_in)
DiseaseProstatic Neoplasms

TRPM4 KMT2C KMT2D STAB2 ETV1 PLAUR NRP1

7.61e-04616727C0033578
DiseaseMalignant neoplasm of prostate

TRPM4 KMT2C KMT2D STAB2 ETV1 PLAUR NRP1

7.61e-04616727C0376358
Diseasecorneal resistance factor

RANBP17 ZNF469 FBN1 ADAMTS2 TSPAN10 ZNF516

8.23e-04451726EFO_0010067
Diseaseischemia (biomarker_via_orthology)

ARID1B PTGES

8.76e-0418722DOID:326 (biomarker_via_orthology)
DiseaseAsthma

TRPA1 TBX21 NOS2

1.00e-0380723C0004096
Diseasechronic hepatitis B virus infection

ETV1 NOTCH4

1.57e-0324722EFO_0004239
DiseaseIntrahepatic Cholangiocarcinoma

KMT2C NOS2

1.57e-0324722C0345905
DiseaseExtrahepatic Cholangiocarcinoma

KMT2C NOS2

1.57e-0324722C3805278
DiseaseCarcinoma, Pancreatic Ductal

NOTCH3 NOTCH4

1.57e-0324722C0887833
Diseasesystemic scleroderma (is_implicated_in)

FBN1 NOTCH4

1.57e-0324722DOID:418 (is_implicated_in)
DiseaseSquamous cell carcinoma of esophagus

KMT2C KMT2D NOTCH3

1.64e-0395723C0279626
DiseaseCholangiocarcinoma

KMT2C NOS2

1.84e-0326722C0206698
DiseaseSezary Syndrome

KMT2C KMT2D

1.98e-0327722C0036920
Diseaseeye colour measurement

ZNF469 ARID1B ROR2 TMPRSS5

2.01e-03218724EFO_0009764
Diseasehypertension (biomarker_via_orthology)

ARID1B FBN1 NOS2 ADCY5

2.33e-03227724DOID:10763 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GHYRAPGEGPQVACT

EPHA1

316

P21709
QFHPEGAGACYGRGV

ARSD

486

P51689
QPGGSIHFGCNAGYR

CSMD2

2486

Q7Z408
CTRNTHGSGIYPGNP

ADGRA3

376

Q8IWK6
EQQCEPGGPQGYSCH

CD248

281

Q9HCU0
DDGQQASPYHPGSCG

ELF3

171

P78545
SQCNHYPGYSRPGAG

ARID1B

376

Q8NFD5
DSRANGYPHAPGGSA

ADCY5

36

O95622
GYVRHVDNPNGDGRC

EGLN3

131

Q9H6Z9
LSFYHPPGEGNEGCA

ATP2B2

121

Q01814
PHPANGGRTCSGLAY

ADAMTS2

591

O95450
NPQGLSDPGNYHEFC

RANBP17

316

Q9H2T7
NCRIAEYSHPQLGGG

PCDH17

741

O14917
GHGNYQNCPVVRPHA

RGS3

521

P49796
NYLPGEHLGVCPGNQ

NOS2

766

P35228
QRICPPGFYGHGCAQ

MEGF11

606

A6BM72
SNGAHFICNYGPGGN

GLIPR1

166

P48060
GGPARYINHSCAPNC

KMT2C

4841

Q8NEZ4
ENTPGGHRCSCPRGY

HMCN2

4731

Q8NDA2
VCQRYAGANGPFPHE

LRP5

1411

O75197
CNNSAPRGLQEPYGG

KIAA1614

881

Q5VZ46
GSGPRRGAHQNAQPC

PER3

756

P56645
GAQGYVRNPPVGACD

NUDT6

31

P53370
PEGGCCNPHPYNEGY

ETV1

461

P50549
RPGYTGAHCQHEADP

NOTCH3

951

Q9UM47
GGLGEHNYCRNPDGD

KREMEN1

76

Q96MU8
YNNGARPCGCHEVGA

LAMA5

1431

O15230
GHQAPEGFCQRSAPG

DDX11

846

Q96FC9
GLGPHAYCRNPDNDE

HGFAC

331

Q04756
APGGPFHCQYGVLGE

HIDE1

81

A8MVS5
YRQGCPGAAGQAPGA

PEF1

6

Q9UBV8
FYGNGKHCLPEGAPH

NID2

516

Q14112
GFPDVGPHIGRYCGQ

NRP1

216

O14786
SHCQACPPGYQGDGR

CUBN

331

O60494
SYAIPCPHLQAGGGA

FZD1

576

Q9UP38
GSPNCHFGPYDNKAR

GALNS

161

P34059
TPGQAQHYEGDRLCG

FCGBP

661

Q9Y6R7
NTEGSYRCECPPGHQ

FBN1

1131

P35555
PRSCDVGGGNAFPHN

CRTC3

241

Q6UUV7
PCRPGIYHFQAQGGS

FSCN3

421

Q9NQT6
MPRNSGAGYGCPHGD

ACSBG1

1

Q96GR2
SRDCDPPGNPVHGYF

C4BPB

136

P20851
CPAGYQAAPHGASCQ

LTBP4

656

Q8N2S1
GDVYRCPVGGAHNAP

ITGA10

71

O75578
YLFVVSGCQGPGHQP

KLHDC7A

541

Q5VTJ3
EPLYAGNACGGPSAA

FIGNL2

141

A6NMB9
GNACGGPSAAPEYAA

FIGNL2

146

A6NMB9
YPTPNGHCANGEAGR

MTMR3

951

Q13615
GYHGPSCQQRCPPGR

MEGF6

1196

O75095
ILQDCYGDGPGPARH

RTP5

121

Q14D33
GNHYSDGPNPEVESC

USP9X

991

Q93008
GPFGQCHAQVSPAEY

SSPOP

401

A2VEC9
DNPAGCSGSAGYPER

NHSL2

446

Q5HYW2
CYLNRGDGPCHPAAG

FEZF1

161

A0PJY2
PGSSHPGEEECRNGY

SETD5

871

Q9C0A6
GHAYCRNPGGQMEGP

ROR2

361

Q01974
NPEDALRHGGPQYCR

PTGES

46

O14684
AHGGTCYPQPSGYNC

NOTCH4

701

Q99466
NGSYFAHVNPADGGC

C11orf54

126

Q9H0W9
RFPELNGGHSYCRNP

ROR1

351

Q01973
GPDGYRQTKPCHGQE

ZNF516

881

Q92618
DMNHPPSGEYFGQCG

TRIP6

266

Q15654
NDGCTPLHYACRQGG

TRPA1

411

O75762
PLHYACRQGGPGSVN

TRPA1

416

O75762
YLPGCPGSNGFHNND

PLAUR

171

Q03405
GANLQPCGTCPGAYH

PHF21B

361

Q96EK2
HGPPFQEGKTNYSCG

ZNF587

201

Q96SQ5
NQYHDCSAPGPLACG

TSPAN15

166

O95858
HGPPFQEGKTNYSCG

ZNF417

201

Q8TAU3
GRGCAEPNHPGVYAK

TMPRSS5

426

Q9H3S3
YSEPGRNNEQPGLCG

USP15

276

Q9Y4E8
GPNRHSCTCQEGYRG

STAB2

256

Q8WWQ8
PCYQGQPGGLNRHSD

ZNF469

336

Q96JG9
AYGPGAHGEDRAGPQ

TSPAN10

326

Q9H1Z9
SPPGPNCQFLGGDHY

TBX21

341

Q9UL17
AHPPGAQAGTCVSQY

TRPM4

1001

Q8TD43
RLHTGNGQGWPACPY

ZNF783

456

Q6ZMS7
TGGPARYINHSCAPN

KMT2D

5466

O14686