Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	toxic substance binding	AHR CHRFAM7A CHRNA7	1.48e-05	18	54	3	GO:0015643
GeneOntologyMolecularFunction	nitric-oxide synthase activity	NOS1 NOS2	2.15e-05	3	54	2	GO:0004517
GeneOntologyMolecularFunction	tetrahydrobiopterin binding	NOS1 NOS2	4.29e-05	4	54	2	GO:0034617
GeneOntologyMolecularFunction	protein-folding chaperone binding	FICD AHR ATP1A1 DNAJB5 APP	7.36e-05	161	54	5	GO:0051087
GeneOntologyMolecularFunction	ATPase binding	ADCY10 CHRFAM7A NOS1 CHRNA7	2.08e-04	108	54	4	GO:0051117
GeneOntologyMolecularFunction	kinase binding	ADAM9 KIF14 IGSF9B ATP1A1 APP CHRFAM7A NOS2 CHRNA7 STAT3 HTT	2.36e-04	969	54	10	GO:0019900
GeneOntologyMolecularFunction	arginine binding	NOS1 NOS2	2.55e-04	9	54	2	GO:0034618
GeneOntologyMolecularFunction	P-type sodium transporter activity	ATP1A1 ATP12A	3.19e-04	10	54	2	GO:0008554
GeneOntologyMolecularFunction	P-type sodium:potassium-exchanging transporter activity	ATP1A1 ATP12A	3.19e-04	10	54	2	GO:0005391
GeneOntologyMolecularFunction	P-type potassium transmembrane transporter activity	ATP1A1 ATP12A	3.89e-04	11	54	2	GO:0008556
GeneOntologyMolecularFunction	acetylcholine binding	CHRFAM7A CHRNA7	5.49e-04	13	54	2	GO:0042166
GeneOntologyMolecularFunction	NADP binding	DUOX1 NOS1 NOS2	6.32e-04	62	54	3	GO:0050661
GeneOntologyMolecularFunction	chloride channel regulator activity	CHRFAM7A CHRNA7	7.37e-04	15	54	2	GO:0017081
GeneOntologyMolecularFunction	adenylate cyclase binding	CHRFAM7A CHRNA7	8.41e-04	16	54	2	GO:0008179
GeneOntologyMolecularFunction	FMN binding	NOS1 NOS2	8.41e-04	16	54	2	GO:0010181
GeneOntologyMolecularFunction	acetylcholine-gated monoatomic cation-selective channel activity	CHRFAM7A CHRNA7	9.51e-04	17	54	2	GO:0022848
GeneOntologyMolecularFunction	heat shock protein binding	FICD AHR NOS2 HTT	9.85e-04	163	54	4	GO:0031072
GeneOntologyMolecularFunction	channel regulator activity	CACNG3 CHRFAM7A NOS1 CHRNA7	1.25e-03	174	54	4	GO:0016247
GeneOntologyMolecularFunction	transporter regulator activity	CACNG3 CHRFAM7A NOS1 CHRNA7	1.34e-03	177	54	4	GO:0141108
GeneOntologyMolecularFunction	peptide binding	LVRN PCSK5 PFDN5 CHRFAM7A CHRNA7	1.66e-03	318	54	5	GO:0042277
GeneOntologyMolecularFunction	acetylcholine receptor activity	CHRFAM7A CHRNA7	1.75e-03	23	54	2	GO:0015464
GeneOntologyMolecularFunction	scaffold protein binding	CHRFAM7A NOS1 CHRNA7	2.04e-03	93	54	3	GO:0097110
GeneOntologyMolecularFunction	endopeptidase regulator activity	COL7A1 NLRP1 APP BIRC6	2.13e-03	201	54	4	GO:0061135
GeneOntologyMolecularFunction	protein kinase binding	ADAM9 KIF14 ATP1A1 APP CHRFAM7A NOS2 CHRNA7 STAT3	2.26e-03	873	54	8	GO:0019901
GeneOntologyMolecularFunction	amyloid-beta binding	PFDN5 CHRFAM7A CHRNA7	2.66e-03	102	54	3	GO:0001540
GeneOntologyMolecularFunction	monooxygenase activity	AHR NOS1 NOS2	3.73e-03	115	54	3	GO:0004497
GeneOntologyMolecularFunction	P-type transmembrane transporter activity	ATP1A1 ATP12A	4.26e-03	36	54	2	GO:0140358
GeneOntologyMolecularFunction	P-type ion transporter activity	ATP1A1 ATP12A	4.26e-03	36	54	2	GO:0015662
GeneOntologyBiologicalProcess	positive regulation of nucleotide metabolic process	ADCY10 APP SLC4A4 NOS1 NOS2 PRXL2C STAT3	1.19e-10	55	55	7	GO:0045981
GeneOntologyBiologicalProcess	positive regulation of purine nucleotide metabolic process	ADCY10 APP SLC4A4 NOS1 NOS2 PRXL2C STAT3	1.19e-10	55	55	7	GO:1900544
GeneOntologyBiologicalProcess	regulation of purine nucleotide metabolic process	ADCY10 APP SLC4A4 NOS1 NOS2 PRXL2C STAT3	1.89e-08	112	55	7	GO:1900542
GeneOntologyBiologicalProcess	regulation of nucleotide metabolic process	ADCY10 APP SLC4A4 NOS1 NOS2 PRXL2C STAT3	2.01e-08	113	55	7	GO:0006140
GeneOntologyBiologicalProcess	regulation of amyloid fibril formation	PFDN5 APP CHRFAM7A CHRNA7	1.70e-07	19	55	4	GO:1905906
GeneOntologyBiologicalProcess	positive regulation of ATP metabolic process	ADCY10 APP SLC4A4 PRXL2C STAT3	1.76e-07	48	55	5	GO:1903580
GeneOntologyBiologicalProcess	positive regulation of purine nucleotide biosynthetic process	ADCY10 NOS1 NOS2 STAT3	5.49e-07	25	55	4	GO:1900373
GeneOntologyBiologicalProcess	positive regulation of nucleotide biosynthetic process	ADCY10 NOS1 NOS2 STAT3	5.49e-07	25	55	4	GO:0030810
GeneOntologyBiologicalProcess	positive regulation of small molecule metabolic process	ADCY10 APP SLC4A4 NOS1 NOS2 PRXL2C STAT3	7.55e-07	192	55	7	GO:0062013
GeneOntologyBiologicalProcess	positive regulation of long-term synaptic potentiation	APP CHRFAM7A NOS1 CHRNA7	1.98e-06	34	55	4	GO:1900273
GeneOntologyBiologicalProcess	regulation of carbohydrate catabolic process	ADCY10 APP SLC4A4 PRXL2C STAT3	2.61e-06	82	55	5	GO:0043470
GeneOntologyBiologicalProcess	regulation of purine nucleotide biosynthetic process	ADCY10 NOS1 NOS2 STAT3	3.85e-06	40	55	4	GO:1900371
GeneOntologyBiologicalProcess	regulation of nucleotide biosynthetic process	ADCY10 NOS1 NOS2 STAT3	3.85e-06	40	55	4	GO:0030808
GeneOntologyBiologicalProcess	regulation of ATP metabolic process	ADCY10 APP SLC4A4 PRXL2C STAT3	4.37e-06	91	55	5	GO:1903578
GeneOntologyBiologicalProcess	regulation of generation of precursor metabolites and energy	ADCY10 APP SLC4A4 NOS2 PRXL2C STAT3	5.76e-06	169	55	6	GO:0043467
GeneOntologyBiologicalProcess	amyloid fibril formation	PFDN5 APP CHRFAM7A CHRNA7	6.21e-06	45	55	4	GO:1990000
GeneOntologyBiologicalProcess	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	CHRFAM7A CHRNA7	6.98e-06	2	55	2	GO:0001988
GeneOntologyBiologicalProcess	export from cell	EXOC6 MIA2 GPR68 ADAM9 EXOC6B ATP1A1 ATP12A SLC4A4 CHRFAM7A NOS1 NOS2 CHRNA7 HTT	7.83e-06	1153	55	13	GO:0140352
GeneOntologyBiologicalProcess	sodium ion export across plasma membrane	ATP1A1 ATP12A SLC4A4	1.19e-05	17	55	3	GO:0036376
GeneOntologyBiologicalProcess	positive regulation of phosphate metabolic process	ADCY10 ADAM9 KIF14 APP SLC4A4 CHRFAM7A NOS1 NOS2 PRXL2C CHRNA7 STAT3	1.70e-05	879	55	11	GO:0045937
GeneOntologyBiologicalProcess	positive regulation of phosphorus metabolic process	ADCY10 ADAM9 KIF14 APP SLC4A4 CHRFAM7A NOS1 NOS2 PRXL2C CHRNA7 STAT3	1.70e-05	879	55	11	GO:0010562
GeneOntologyBiologicalProcess	baroreceptor response to decreased systemic arterial blood pressure	CHRFAM7A CHRNA7	2.09e-05	3	55	2	GO:0001982
GeneOntologyBiologicalProcess	regulation of interleukin-1 beta production	NLRP1 APP CHRFAM7A CHRNA7 STAT3	2.40e-05	129	55	5	GO:0032651
GeneOntologyBiologicalProcess	regulation of nucleotide catabolic process	APP SLC4A4 PRXL2C STAT3	2.40e-05	63	55	4	GO:0030811
GeneOntologyBiologicalProcess	regulation of purine nucleotide catabolic process	APP SLC4A4 PRXL2C STAT3	2.40e-05	63	55	4	GO:0033121
GeneOntologyBiologicalProcess	regulation of glycolytic process	APP SLC4A4 PRXL2C STAT3	2.40e-05	63	55	4	GO:0006110
GeneOntologyBiologicalProcess	regulation of blood circulation	ADCY10 AHR ATP1A1 APP CHRFAM7A NOS1 CHRNA7	2.45e-05	326	55	7	GO:1903522
GeneOntologyBiologicalProcess	interleukin-1 beta production	NLRP1 APP CHRFAM7A CHRNA7 STAT3	2.98e-05	135	55	5	GO:0032611
GeneOntologyBiologicalProcess	regulation of long-term synaptic potentiation	APP CHRFAM7A NOS1 CHRNA7	3.06e-05	67	55	4	GO:1900271
GeneOntologyBiologicalProcess	postsynaptic signal transduction	CHRFAM7A CHRNA7 STAT3 HTT	3.44e-05	69	55	4	GO:0098926
GeneOntologyBiologicalProcess	pyruvate metabolic process	APP SLC4A4 PRXL2C STAT3 HTT	3.80e-05	142	55	5	GO:0006090
GeneOntologyBiologicalProcess	regulation of blood pressure	AHR ATP1A1 CHRFAM7A NOS1 NOS2 CHRNA7	3.91e-05	237	55	6	GO:0008217
GeneOntologyBiologicalProcess	generation of ovulation cycle rhythm	CHRFAM7A CHRNA7	4.17e-05	4	55	2	GO:0060112
GeneOntologyBiologicalProcess	amyloid precursor protein catabolic process	ADAM9 APP CHRFAM7A CHRNA7	4.30e-05	73	55	4	GO:0042987
GeneOntologyBiologicalProcess	reactive oxygen species biosynthetic process	ADCY10 DUOX1 AHR STAT3	6.16e-05	80	55	4	GO:1903409
GeneOntologyBiologicalProcess	positive regulation of amyloid precursor protein catabolic process	APP CHRFAM7A CHRNA7	6.24e-05	29	55	3	GO:1902993
GeneOntologyBiologicalProcess	positive regulation of glycolytic process	APP SLC4A4 PRXL2C	6.24e-05	29	55	3	GO:0045821
GeneOntologyBiologicalProcess	positive regulation of nucleotide catabolic process	APP SLC4A4 PRXL2C	6.24e-05	29	55	3	GO:0030813
GeneOntologyBiologicalProcess	positive regulation of purine nucleotide catabolic process	APP SLC4A4 PRXL2C	6.24e-05	29	55	3	GO:0033123
GeneOntologyBiologicalProcess	sensory processing	CHRFAM7A CHRNA7	6.95e-05	5	55	2	GO:0050893
GeneOntologyBiologicalProcess	regulation of interleukin-1 production	NLRP1 APP CHRFAM7A CHRNA7 STAT3	7.76e-05	165	55	5	GO:0032652
GeneOntologyBiologicalProcess	negative regulation of blood circulation	ADCY10 ATP1A1 APP	8.42e-05	32	55	3	GO:1903523
GeneOntologyBiologicalProcess	interleukin-1 production	NLRP1 APP CHRFAM7A CHRNA7 STAT3	9.19e-05	171	55	5	GO:0032612
GeneOntologyBiologicalProcess	regulation of hydrolase activity	COL7A1 FICD NLRP1 APP BIRC6 NOS1 PLXNA1 PREX2 STAT3 HTT	9.51e-05	878	55	10	GO:0051336
GeneOntologyBiologicalProcess	positive regulation of guanylate cyclase activity	NOS1 NOS2	1.04e-04	6	55	2	GO:0031284
GeneOntologyBiologicalProcess	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback	CHRFAM7A CHRNA7	1.04e-04	6	55	2	GO:0001978
GeneOntologyBiologicalProcess	regulation of membrane potential	ADCY10 IGSF9B ATP1A1 APP SLC4A4 CHRFAM7A NOS1 CHRNA7	1.10e-04	559	55	8	GO:0042391
GeneOntologyBiologicalProcess	regulation of postsynaptic membrane potential	IGSF9B APP CHRFAM7A NOS1 CHRNA7	1.17e-04	180	55	5	GO:0060078
GeneOntologyBiologicalProcess	reactive oxygen species metabolic process	ADCY10 DUOX1 AHR APP NOS2 STAT3	1.22e-04	291	55	6	GO:0072593
GeneOntologyBiologicalProcess	circulatory system process	ADCY10 AHR ATP1A1 APP SLC4A4 CHRFAM7A NOS1 NOS2 CHRNA7	1.26e-04	733	55	9	GO:0003013
GeneOntologyBiologicalProcess	regulation of small molecule metabolic process	ADCY10 APP SLC4A4 NOS1 NOS2 PRXL2C STAT3	1.48e-04	434	55	7	GO:0062012
GeneOntologyBiologicalProcess	amyloid precursor protein metabolic process	ADAM9 APP CHRFAM7A CHRNA7	1.52e-04	101	55	4	GO:0042982
GeneOntologyBiologicalProcess	positive regulation of peptidyl-serine phosphorylation	APP CHRFAM7A NOS1 CHRNA7	1.52e-04	101	55	4	GO:0033138
GeneOntologyBiologicalProcess	carbohydrate catabolic process	ADCY10 APP SLC4A4 PRXL2C STAT3	1.74e-04	196	55	5	GO:0016052
GeneOntologyBiologicalProcess	positive regulation of carbohydrate metabolic process	ADCY10 APP SLC4A4 PRXL2C	1.77e-04	105	55	4	GO:0045913
GeneOntologyBiologicalProcess	regulation of guanylate cyclase activity	NOS1 NOS2	1.93e-04	8	55	2	GO:0031282
GeneOntologyBiologicalProcess	regulation of systemic arterial blood pressure by baroreceptor feedback	CHRFAM7A CHRNA7	1.93e-04	8	55	2	GO:0003025
GeneOntologyBiologicalProcess	intracellular monoatomic cation homeostasis	PKHD1 ATP1A1 APP ATP12A SLC4A4 NOS1 CHRNA7 HTT	2.02e-04	611	55	8	GO:0030003
GeneOntologyBiologicalProcess	adult behavior	APP CHRFAM7A NOS1 PREX2 CHRNA7	2.05e-04	203	55	5	GO:0030534
GeneOntologyBiologicalProcess	positive regulation of excitatory postsynaptic potential	APP CHRFAM7A CHRNA7	2.05e-04	43	55	3	GO:2000463
GeneOntologyBiologicalProcess	glycolytic process	APP SLC4A4 PRXL2C STAT3	2.12e-04	110	55	4	GO:0006096
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	PKHD1 ATP1A1 APP ATP12A SLC4A4 NOS1 CHRNA7 HTT	2.28e-04	622	55	8	GO:0006873
GeneOntologyBiologicalProcess	cellular homeostasis	GPR68 PKHD1 ATP1A1 APP ATP12A SLC4A4 NOS1 NOS2 CHRNA7 HTT	2.35e-04	981	55	10	GO:0019725
GeneOntologyBiologicalProcess	pyridine-containing compound metabolic process	APP SLC4A4 PRXL2C STAT3 HTT	2.40e-04	210	55	5	GO:0072524
GeneOntologyBiologicalProcess	ADP catabolic process	APP SLC4A4 PRXL2C STAT3	2.43e-04	114	55	4	GO:0046032
GeneOntologyBiologicalProcess	positive regulation of CoA-transferase activity	CHRFAM7A CHRNA7	2.48e-04	9	55	2	GO:1905920
GeneOntologyBiologicalProcess	vesicle tethering involved in exocytosis	EXOC6 EXOC6B	2.48e-04	9	55	2	GO:0090522
GeneOntologyBiologicalProcess	regulation of interleukin-6 production	APP CHRFAM7A NOS2 CHRNA7 STAT3	2.51e-04	212	55	5	GO:0032675
GeneOntologyBiologicalProcess	purine nucleoside diphosphate catabolic process	APP SLC4A4 PRXL2C STAT3	2.68e-04	117	55	4	GO:0009137
GeneOntologyBiologicalProcess	purine ribonucleoside diphosphate catabolic process	APP SLC4A4 PRXL2C STAT3	2.68e-04	117	55	4	GO:0009181
GeneOntologyBiologicalProcess	pyridine nucleotide catabolic process	APP SLC4A4 PRXL2C STAT3	2.86e-04	119	55	4	GO:0019364
GeneOntologyBiologicalProcess	ADP metabolic process	APP SLC4A4 PRXL2C STAT3	2.96e-04	120	55	4	GO:0046031
GeneOntologyBiologicalProcess	regulation of phosphate metabolic process	ADCY10 ADAM9 KIF14 APP SLC4A4 CHRFAM7A NOS1 NOS2 PRXL2C CHRNA7 STAT3 HTT	2.99e-04	1421	55	12	GO:0019220
GeneOntologyBiologicalProcess	blood circulation	ADCY10 AHR ATP1A1 APP CHRFAM7A NOS1 NOS2 CHRNA7	3.01e-04	648	55	8	GO:0008015
GeneOntologyBiologicalProcess	regulation of phosphorus metabolic process	ADCY10 ADAM9 KIF14 APP SLC4A4 CHRFAM7A NOS1 NOS2 PRXL2C CHRNA7 STAT3 HTT	3.03e-04	1423	55	12	GO:0051174
GeneOntologyBiologicalProcess	positive regulation of heart contraction	ATP1A1 CHRFAM7A CHRNA7	3.03e-04	49	55	3	GO:0045823
GeneOntologyBiologicalProcess	interleukin-6 production	APP CHRFAM7A NOS2 CHRNA7 STAT3	3.04e-04	221	55	5	GO:0032635
GeneOntologyBiologicalProcess	ribonucleoside diphosphate catabolic process	APP SLC4A4 PRXL2C STAT3	3.05e-04	121	55	4	GO:0009191
GeneOntologyBiologicalProcess	positive regulation of rRNA processing	RIOK1 WDR75	3.10e-04	10	55	2	GO:2000234
GeneOntologyBiologicalProcess	arginine catabolic process	NOS1 NOS2	3.10e-04	10	55	2	GO:0006527
GeneOntologyBiologicalProcess	pyridine-containing compound catabolic process	APP SLC4A4 PRXL2C STAT3	3.25e-04	123	55	4	GO:0072526
GeneOntologyBiologicalProcess	nucleoside diphosphate catabolic process	APP SLC4A4 PRXL2C STAT3	3.35e-04	124	55	4	GO:0009134
GeneOntologyBiologicalProcess	neuron projection organization	ADCY10 APP CHRFAM7A CHRNA7	3.67e-04	127	55	4	GO:0106027
GeneOntologyBiologicalProcess	regulation of carbohydrate metabolic process	ADCY10 APP SLC4A4 PRXL2C STAT3	3.72e-04	231	55	5	GO:0006109
GeneOntologyBiologicalProcess	establishment or maintenance of transmembrane electrochemical gradient	ATP1A1 ATP12A	3.78e-04	11	55	2	GO:0010248
GeneOntologyBiologicalProcess	regulation of CoA-transferase activity	CHRFAM7A CHRNA7	3.78e-04	11	55	2	GO:1905918
GeneOntologyBiologicalProcess	behavioral response to nicotine	CHRFAM7A CHRNA7	3.78e-04	11	55	2	GO:0035095
GeneOntologyBiologicalProcess	positive regulation of blood circulation	ATP1A1 CHRFAM7A CHRNA7	3.82e-04	53	55	3	GO:1903524
GeneOntologyBiologicalProcess	regulation of actin filament-based movement	ADCY10 ATP1A1 NOS1	3.82e-04	53	55	3	GO:1903115
GeneOntologyBiologicalProcess	positive regulation of synaptic transmission	CACNG3 APP CHRFAM7A NOS1 CHRNA7	3.87e-04	233	55	5	GO:0050806
GeneOntologyBiologicalProcess	chemical homeostasis	MIA2 GPR68 PKHD1 ATP1A1 APP ATP12A SLC4A4 NOS1 CHRNA7 STAT3 HTT	3.90e-04	1249	55	11	GO:0048878
GeneOntologyBiologicalProcess	response to organic cyclic compound	DUOX1 ADAM9 AHR ATP1A1 APP ATP12A NOS1 NOS2 STAT3 HTT	3.98e-04	1048	55	10	GO:0014070
GeneOntologyBiologicalProcess	associative learning	APP CHRFAM7A CHRNA7 HTT	4.01e-04	130	55	4	GO:0008306
GeneOntologyBiologicalProcess	cellular catabolic process	LVRN ADCY10 DUOX1 ADAM9 APP SLC4A4 NOS1 NOS2 PRXL2C STAT3 HTT	4.01e-04	1253	55	11	GO:0044248
GeneOntologyBiologicalProcess	purine nucleoside diphosphate metabolic process	APP SLC4A4 PRXL2C STAT3	4.25e-04	132	55	4	GO:0009135
GeneOntologyBiologicalProcess	purine ribonucleoside diphosphate metabolic process	APP SLC4A4 PRXL2C STAT3	4.25e-04	132	55	4	GO:0009179
GeneOntologyBiologicalProcess	intracellular chemical homeostasis	GPR68 PKHD1 ATP1A1 APP ATP12A SLC4A4 NOS1 CHRNA7 HTT	4.35e-04	866	55	9	GO:0055082
GeneOntologyBiologicalProcess	secretion by cell	EXOC6 MIA2 GPR68 ADAM9 EXOC6B CHRFAM7A NOS1 NOS2 CHRNA7 HTT	4.49e-04	1064	55	10	GO:0032940
GeneOntologyBiologicalProcess	membrane repolarization	ADCY10 ATP1A1 NOS1	4.50e-04	56	55	3	GO:0086009
GeneOntologyBiologicalProcess	regulation of synapse structural plasticity	CHRFAM7A CHRNA7	4.53e-04	12	55	2	GO:0051823
GeneOntologyCellularComponent	spine apparatus membrane	CHRFAM7A CHRNA7	2.04e-05	3	55	2	GO:0098897
GeneOntologyCellularComponent	Flemming body	EXOC6 KIF14 BIRC6	1.16e-04	36	55	3	GO:0090543
GeneOntologyCellularComponent	apical part of cell	ADCY10 DUOX1 PKHD1 ATP1A1 APP ATP12A CHRFAM7A CHRNA7	1.49e-04	592	55	8	GO:0045177
GeneOntologyCellularComponent	spine apparatus	CHRFAM7A CHRNA7	2.42e-04	9	55	2	GO:0097444
GeneOntologyCellularComponent	asymmetric synapse	CACNG3 IGSF9B ATP1A1 CHRFAM7A NOS1 CHRNA7 STAT3	2.43e-04	477	55	7	GO:0032279
GeneOntologyCellularComponent	apical plasma membrane	ADCY10 DUOX1 PKHD1 ATP1A1 ATP12A CHRFAM7A CHRNA7	2.75e-04	487	55	7	GO:0016324
GeneOntologyCellularComponent	postsynaptic specialization	CACNG3 IGSF9B ATP1A1 CHRFAM7A NOS1 CHRNA7 STAT3	3.35e-04	503	55	7	GO:0099572
GeneOntologyCellularComponent	dendrite	CACNG3 ADCY10 PCSK5 IGSF9B APP CHRFAM7A NOS1 CHRNA7 HTT	3.69e-04	858	55	9	GO:0030425
GeneOntologyCellularComponent	dendritic tree	CACNG3 ADCY10 PCSK5 IGSF9B APP CHRFAM7A NOS1 CHRNA7 HTT	3.76e-04	860	55	9	GO:0097447
GeneOntologyCellularComponent	neuron to neuron synapse	CACNG3 IGSF9B ATP1A1 CHRFAM7A NOS1 CHRNA7 STAT3	4.23e-04	523	55	7	GO:0098984
GeneOntologyCellularComponent	growth cone	ADCY10 EXOC6 APP CHRFAM7A CHRNA7	4.58e-04	245	55	5	GO:0030426
GeneOntologyCellularComponent	site of polarized growth	ADCY10 EXOC6 APP CHRFAM7A CHRNA7	5.30e-04	253	55	5	GO:0030427
GeneOntologyCellularComponent	plasma membrane raft	ATP1A1 CHRFAM7A NOS1 CHRNA7	6.06e-04	147	55	4	GO:0044853
GeneOntologyCellularComponent	distal axon	ADCY10 EXOC6 APP CHRFAM7A NOS1 CHRNA7	9.61e-04	435	55	6	GO:0150034
GeneOntologyCellularComponent	dendritic shaft	APP CHRFAM7A CHRNA7	9.79e-04	74	55	3	GO:0043198
GeneOntologyCellularComponent	acetylcholine-gated channel complex	CHRFAM7A CHRNA7	1.01e-03	18	55	2	GO:0005892
GeneOntologyCellularComponent	glycinergic synapse	CHRFAM7A CHRNA7	1.25e-03	20	55	2	GO:0098690
GeneOntologyCellularComponent	postsynapse	CACNG3 IGSF9B ATP1A1 APP CHRFAM7A NOS1 CHRNA7 STAT3 HTT	1.25e-03	1018	55	9	GO:0098794
GeneOntologyCellularComponent	exocyst	EXOC6 EXOC6B	1.38e-03	21	55	2	GO:0000145
GeneOntologyCellularComponent	axolemma	CHRFAM7A CHRNA7	1.38e-03	21	55	2	GO:0030673
GeneOntologyCellularComponent	cholinergic synapse	CHRFAM7A CHRNA7	1.52e-03	22	55	2	GO:0098981
GeneOntologyCellularComponent	main axon	APP CHRFAM7A CHRNA7	1.67e-03	89	55	3	GO:0044304
GeneOntologyCellularComponent	astrocyte projection	ADCY10 APP	1.96e-03	25	55	2	GO:0097449
GeneOntologyCellularComponent	axon	ADCY10 EXOC6 ATP1A1 APP CHRFAM7A NOS1 CHRNA7 HTT	2.17e-03	891	55	8	GO:0030424
GeneOntologyCellularComponent	membrane raft	ATP1A1 APP CHRFAM7A NOS1 CHRNA7	2.59e-03	362	55	5	GO:0045121
GeneOntologyCellularComponent	membrane microdomain	ATP1A1 APP CHRFAM7A NOS1 CHRNA7	2.65e-03	364	55	5	GO:0098857
GeneOntologyCellularComponent	basal part of cell	ADCY10 ADAM9 ATP1A1 ATP12A SLC4A4	3.12e-03	378	55	5	GO:0045178
GeneOntologyCellularComponent	intracellular protein-containing complex	SF3B3 PHF20L1 NFKB2 RPP30 AHR AKAP14 ZSWIM6 FBXO21	3.71e-03	972	55	8	GO:0140535
GeneOntologyCellularComponent	dendritic spine	APP CHRFAM7A NOS1 CHRNA7	3.76e-03	242	55	4	GO:0043197
GeneOntologyCellularComponent	neuron spine	APP CHRFAM7A NOS1 CHRNA7	4.05e-03	247	55	4	GO:0044309
GeneOntologyCellularComponent	receptor complex	CACNG3 AHR APP CHRFAM7A PLXNA1 CHRNA7	4.10e-03	581	55	6	GO:0043235
GeneOntologyCellularComponent	somatodendritic compartment	CACNG3 ADCY10 PCSK5 IGSF9B APP CHRFAM7A NOS1 CHRNA7 HTT	4.46e-03	1228	55	9	GO:0036477
GeneOntologyCellularComponent	spindle midzone	KIF14 APP	4.97e-03	40	55	2	GO:0051233
GeneOntologyCellularComponent	neuronal cell body	ADCY10 PCSK5 IGSF9B APP CHRFAM7A CHRNA7 HTT	6.05e-03	835	55	7	GO:0043025
GeneOntologyCellularComponent	postsynaptic density	CACNG3 IGSF9B ATP1A1 NOS1 STAT3	6.56e-03	451	55	5	GO:0014069
GeneOntologyCellularComponent	glial cell projection	ADCY10 APP	6.81e-03	47	55	2	GO:0097386
GeneOntologyCellularComponent	cation-transporting ATPase complex	ATP1A1 ATP12A	7.38e-03	49	55	2	GO:0090533
MousePheno	airway basal cell hyperplasia	CHRFAM7A CHRNA7	1.01e-05	2	45	2	MP:0011115
MousePheno	abnormal airway basal cell differentiation	CHRFAM7A CHRNA7	1.01e-05	2	45	2	MP:0011114
MousePheno	abnormal airway basal cell morphology	CHRFAM7A CHRNA7	1.01e-05	2	45	2	MP:0011113
MousePheno	abnormal macrophage morphology	SGMS2 GPR68 NFKB2 NLRP1 APP KMT2E NOS1 NOS2 HTT	1.36e-05	463	45	9	MP:0002446
MousePheno	abnormal apoptosis	PCSK5 ADAMTS3 NFKB2 PKHD1 AHR KIF14 NLRP1 PFDN5 BIRC6 CHRFAM7A NOS1 CHRNA7 STAT3 HTT	5.54e-05	1353	45	14	MP:0001648
MousePheno	abnormal programmed cell death	PCSK5 ADAMTS3 NFKB2 PKHD1 AHR KIF14 NLRP1 PFDN5 BIRC6 CHRFAM7A NOS1 CHRNA7 STAT3 HTT	5.87e-05	1360	45	14	MP:0014355
MousePheno	delayed peripheral nervous system regeneration	NOS1 NOS2	6.05e-05	4	45	2	MP:0031330
MousePheno	abnormal nicotine-mediated receptor currents	CHRFAM7A CHRNA7	6.05e-05	4	45	2	MP:0009475
MousePheno	abnormal mononuclear phagocyte morphology	SGMS2 GPR68 NFKB2 AHR NLRP1 APP KMT2E NOS1 NOS2 HTT	6.39e-05	705	45	10	MP:0008248
MousePheno	abnormal urine pH	SLC4A4 NOS1 NOS2	6.82e-05	25	45	3	MP:0009348
MousePheno	abnormal phagocyte morphology	SGMS2 GPR68 NFKB2 AHR NLRP1 APP KMT2E CHRFAM7A NOS1 NOS2 CHRNA7 HTT	7.28e-05	1033	45	12	MP:0008251
MousePheno	abnormal professional antigen presenting cell morphology	SGMS2 GPR68 NFKB2 AHR NLRP1 APP KMT2E NOS1 NOS2 HTT	8.17e-05	726	45	10	MP:0008195
MousePheno	abnormal cerebral cortex pyramidal cell morphology	KIF14 CHRFAM7A CHRNA7	1.45e-04	32	45	3	MP:0009969
MousePheno	failure of neuromuscular synapse presynaptic differentiation	CHRFAM7A CHRNA7	1.51e-04	6	45	2	MP:0001054
MousePheno	bile duct inflammation	PKHD1 AHR	1.51e-04	6	45	2	MP:0003254
MousePheno	abnormal osteoclast differentiation	GPR68 NFKB2 NOS1 NOS2	1.57e-04	85	45	4	MP:0008396
MousePheno	abnormal circulating lipid level	CACNG3 ADCY10 PCSK5 SGMS2 MIA2 CEACAM16 PM20D1 ATP1A1 SLC4A4 CHRFAM7A NOS1 NOS2 CHRNA7	1.63e-04	1305	45	13	MP:0003949
MousePheno	abnormal GABAergic neuron physiology	CHRFAM7A CHRNA7	2.80e-04	8	45	2	MP:0011987
MousePheno	abnormal medium spiny neuron morphology	ZSWIM6 HTT	2.80e-04	8	45	2	MP:0008462
MousePheno	abnormal leukocyte physiology	SGMS2 GPR68 NFKB2 AHR NLRP1 KMT2E BIRC6 CHRFAM7A NOS1 NOS2 PLXNA1 CHRNA7 STAT3	3.91e-04	1425	45	13	MP:0002442
MousePheno	abnormal behavioral response to xenobiotic	ZSWIM6 ATP1A1 CHRFAM7A NOS1 NOS2 CHRNA7	4.38e-04	309	45	6	MP:0009745
MousePheno	decreased susceptibility to induced choroidal neovascularization	NOS1 NOS2	4.49e-04	10	45	2	MP:0003434
MousePheno	abnormal immune cell physiology	SGMS2 GPR68 NFKB2 AHR NLRP1 KMT2E BIRC6 CHRFAM7A NOS1 NOS2 PLXNA1 CHRNA7 STAT3	4.63e-04	1450	45	13	MP:0001819
MousePheno	abnormal anxiety-related response	SF3B3 ZSWIM6 ATP1A1 APP CHRFAM7A NOS1 NOS2 CHRNA7 HTT	4.94e-04	740	45	9	MP:0001362
MousePheno	abnormal cell-mediated immunity	SGMS2 GPR68 NFKB2 AHR NLRP1 KMT2E BIRC6 CHRFAM7A NOS1 NOS2 PLXNA1 CHRNA7 STAT3	5.05e-04	1463	45	13	MP:0002421
MousePheno	abnormal peripheral nervous system regeneration	NOS1 NOS2	5.47e-04	11	45	2	MP:0004220
MousePheno	decreased macrophage cell number	GPR68 NLRP1 KMT2E NOS2	5.50e-04	118	45	4	MP:0003884
MousePheno	abnormal fear/anxiety-related behavior	SF3B3 PHF20L1 ZSWIM6 ATP1A1 APP CHRFAM7A NOS1 NOS2 CHRNA7 HTT	5.54e-04	919	45	10	MP:0002065
MousePheno	abnormal oligodendrocyte morphology	NOS2 PLXNA1 HTT	5.83e-04	51	45	3	MP:0000953
MousePheno	abnormal myeloid leukocyte morphology	SGMS2 GPR68 NFKB2 AHR NLRP1 APP KMT2E CHRFAM7A NOS1 NOS2 CHRNA7 HTT	5.93e-04	1292	45	12	MP:0008250
MousePheno	abnormal adaptive immunity	SGMS2 GPR68 NFKB2 AHR NLRP1 KMT2E BIRC6 CHRFAM7A NOS1 NOS2 PLXNA1 CHRNA7 STAT3	6.03e-04	1490	45	13	MP:0002420
MousePheno	decreased erythroblast number	CHRFAM7A CHRNA7	6.55e-04	12	45	2	MP:0011179
MousePheno	abnormal stomach pyloric region morphology	AHR NOS1	6.55e-04	12	45	2	MP:0010785
MousePheno	metabolic acidosis	SLC4A4 NOS1	6.55e-04	12	45	2	MP:0012551
MousePheno	impaired spatial working memory	CHRFAM7A CHRNA7	6.55e-04	12	45	2	MP:0014370
MousePheno	increased urine pH	NOS1 NOS2	7.73e-04	13	45	2	MP:0009349
MousePheno	abnormal ductus venosus valve topology	ADAMTS3 PRMT7	7.73e-04	13	45	2	MP:0013878
MousePheno	decreased leukocyte cell number	COL7A1 PHF20L1 GPR68 NFKB2 TEDDM1 NLRP1 SLC4A4 KMT2E CHRFAM7A NOS2 CHRNA7 STAT3	8.34e-04	1342	45	12	MP:0000221
MousePheno	abnormal ductus venosus morphology	ADAMTS3 AHR PRMT7	8.50e-04	58	45	3	MP:0013873
Domain	Sec15	EXOC6 EXOC6B	8.21e-06	2	54	2	PF04091
Domain	EXOC6/Sec15	EXOC6 EXOC6B	8.21e-06	2	54	2	IPR007225
Domain	Fd_Rdtase_FAD-bd	DUOX1 NOS1 NOS2	2.14e-05	19	54	3	IPR017927
Domain	FAD_FR	DUOX1 NOS1 NOS2	2.14e-05	19	54	3	PS51384
Domain	Riboflavin_synthase-like_b-brl	DUOX1 NOS1 NOS2	2.14e-05	19	54	3	IPR017938
Domain	-	NOS1 NOS2	2.46e-05	3	54	2	3.90.340.10
Domain	NO_synthase	NOS1 NOS2	2.46e-05	3	54	2	PF02898
Domain	NOS_N	NOS1 NOS2	2.46e-05	3	54	2	IPR004030
Domain	NOS	NOS1 NOS2	2.46e-05	3	54	2	PS60001
Domain	NOS_euk	NOS1 NOS2	2.46e-05	3	54	2	IPR012144
Domain	IPT	NFKB2 PKHD1 PLXNA1	6.36e-05	27	54	3	SM00429
Domain	IPT	NFKB2 PKHD1 PLXNA1	1.07e-04	32	54	3	IPR002909
Domain	FAD_binding_1	NOS1 NOS2	1.22e-04	6	54	2	PF00667
Domain	FAD-binding_1	NOS1 NOS2	1.22e-04	6	54	2	IPR003097
Domain	P-type_ATPase_IIC	ATP1A1 ATP12A	1.22e-04	6	54	2	IPR005775
Domain	-	NOS1 NOS2	1.22e-04	6	54	2	1.20.990.10
Domain	NADPH_Cyt_P450_Rdtase_dom3	NOS1 NOS2	1.22e-04	6	54	2	IPR023173
Domain	FLAVODOXIN_LIKE	NOS1 NOS2	2.27e-04	8	54	2	PS50902
Domain	Flavodoxin/NO_synth	NOS1 NOS2	2.27e-04	8	54	2	IPR008254
Domain	Flavdoxin-like	NOS1 NOS2	2.27e-04	8	54	2	IPR001094
Domain	Flavodoxin_1	NOS1 NOS2	2.27e-04	8	54	2	PF00258
Domain	Flavoprotein-like_dom	NOS1 NOS2	3.64e-04	10	54	2	IPR029039
Domain	Flavoprot_Pyr_Nucl_cyt_Rdtase	NOS1 NOS2	3.64e-04	10	54	2	IPR001709
Domain	-	NOS1 NOS2	3.64e-04	10	54	2	3.40.50.360
Domain	OxRdtase_FAD/NAD-bd	NOS1 NOS2	5.32e-04	12	54	2	IPR001433
Domain	NAD_binding_1	NOS1 NOS2	5.32e-04	12	54	2	PF00175
Domain	-	ATP1A1 ATP12A	9.59e-04	16	54	2	1.20.1110.10
Domain	ATPase_P-typ_TM_dom	ATP1A1 ATP12A	9.59e-04	16	54	2	IPR023298
Domain	ATPase_P-typ_cation-transptr_C	ATP1A1 ATP12A	1.09e-03	17	54	2	IPR006068
Domain	Cation_ATPase_C	ATP1A1 ATP12A	1.09e-03	17	54	2	PF00689
Domain	Cation_ATPase_N	ATP1A1 ATP12A	1.22e-03	18	54	2	PF00690
Domain	Cation_ATPase_N	ATP1A1 ATP12A	1.22e-03	18	54	2	SM00831
Domain	-	COL7A1 APP	1.22e-03	18	54	2	4.10.410.10
Domain	Prtase_inh_Kunz-CS	COL7A1 APP	1.22e-03	18	54	2	IPR020901
Domain	PLAC	PCSK5 ADAMTS3	1.36e-03	19	54	2	PS50900
Domain	BPTI_KUNITZ_2	COL7A1 APP	1.36e-03	19	54	2	PS50279
Domain	ATPase_P-typ_cation-transptr_N	ATP1A1 ATP12A	1.36e-03	19	54	2	IPR004014
Domain	PLAC	PCSK5 ADAMTS3	1.36e-03	19	54	2	IPR010909
Domain	Kunitz_BPTI	COL7A1 APP	1.36e-03	19	54	2	PF00014
Domain	BPTI_KUNITZ_1	COL7A1 APP	1.36e-03	19	54	2	PS00280
Domain	-	CHRFAM7A CHRNA7	2.00e-03	23	54	2	1.20.120.370
Domain	Acetylcholine_rcpt_TM	CHRFAM7A CHRNA7	2.00e-03	23	54	2	IPR027361
Domain	Kunitz_BPTI	COL7A1 APP	2.00e-03	23	54	2	IPR002223
Domain	ZINC_PROTEASE	LVRN ADAMTS3 ADAM9	2.86e-03	98	54	3	PS00142
Domain	Ig_E-set	NFKB2 PKHD1 PLXNA1	3.39e-03	104	54	3	IPR014756
Domain	TIG	PKHD1 PLXNA1	3.62e-03	31	54	2	PF01833
Domain	-	ATP1A1 ATP12A	3.85e-03	32	54	2	3.40.1110.10
Domain	-	ATP1A1 ATP12A	3.85e-03	32	54	2	2.70.150.10
Domain	ATPase_P-typ_cyto_domN	ATP1A1 ATP12A	4.59e-03	35	54	2	IPR023299
Domain	P_typ_ATPase	ATP1A1 ATP12A	4.85e-03	36	54	2	IPR001757
Domain	ATPase_P-typ_P_site	ATP1A1 ATP12A	4.85e-03	36	54	2	IPR018303
Domain	ATPASE_E1_E2	ATP1A1 ATP12A	4.85e-03	36	54	2	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP1A1 ATP12A	5.12e-03	37	54	2	IPR008250
Domain	E1-E2_ATPase	ATP1A1 ATP12A	5.12e-03	37	54	2	PF00122
Domain	Peptidase_M12B_N	ADAMTS3 ADAM9	5.68e-03	39	54	2	IPR002870
Domain	Pep_M12B_propep	ADAMTS3 ADAM9	5.68e-03	39	54	2	PF01562
Pathway	WP_NITRIC_OXIDE_METABOLISM_IN_CYSTIC_FIBROSIS	PRMT7 NOS1 NOS2	7.40e-06	13	43	3	M39894
Pathway	REACTOME_INFLAMMASOMES	NFKB2 NLRP1 APP	3.38e-05	21	43	3	M1072
Pubmed	A novel nicotinic mechanism underlies β-amyloid-induced neuronal hyperexcitation.	APP CHRFAM7A CHRNA7	3.74e-09	3	55	3	23616534
Pubmed	Unphosphorylated STAT3 modulates alpha 7 nicotinic receptor signaling and cytokine production in sepsis.	CHRFAM7A CHRNA7 STAT3	3.74e-09	3	55	3	20706987
Pubmed	Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease.	APP CHRFAM7A CHRNA7	3.74e-09	3	55	3	20164328
Pubmed	Neuromodulatory Action of Picomolar Extracellular Aβ42 Oligomers on Presynaptic and Postsynaptic Mechanisms Underlying Synaptic Function and Memory.	APP CHRFAM7A CHRNA7	3.74e-09	3	55	3	31127002
Pubmed	Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease.	APP CHRFAM7A CHRNA7	3.74e-09	3	55	3	19587288
Pubmed	Role of key aromatic residues in the ligand-binding domain of alpha7 nicotinic receptors in the agonist action of beta-amyloid.	APP CHRFAM7A CHRNA7	3.74e-09	3	55	3	21828053
Pubmed	Activation of nicotinic α(7) acetylcholine receptor enhances long term potentation in wild type mice but not in APP(swe)/PS1ΔE9 mice.	APP CHRFAM7A CHRNA7	3.74e-09	3	55	3	20974225
Pubmed	Amyloid-β peptide increases cell surface localization of α7 ACh receptor to protect neurons from amyloid β-induced damage.	APP CHRFAM7A CHRNA7	3.74e-09	3	55	3	26522221
Pubmed	Cross-talk between α7 nAChR-mediated cholinergic pathway and acylation stimulating protein signaling in 3T3-L1 adipocytes: role of NFκB and STAT3.	CHRFAM7A CHRNA7 STAT3	3.74e-09	3	55	3	25985797
Pubmed	Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway.	CHRFAM7A CHRNA7 STAT3	1.50e-08	4	55	3	16025117
Pubmed	Implications of Oligomeric Amyloid-Beta (oAβ42) Signaling through α7β2-Nicotinic Acetylcholine Receptors (nAChRs) on Basal Forebrain Cholinergic Neuronal Intrinsic Excitability and Cognitive Decline.	APP CHRFAM7A CHRNA7	1.50e-08	4	55	3	33239400
Pubmed	Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins.	APP CHRFAM7A CHRNA7	1.50e-08	4	55	3	11912199
Pubmed	α7 Nicotinic Acetylcholine Receptor Stimulation Attenuates Neuroinflammation through JAK2-STAT3 Activation in Murine Models of Intracerebral Hemorrhage.	CHRFAM7A CHRNA7 STAT3	1.50e-08	4	55	3	28529954
Pubmed	Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus.	APP CHRFAM7A CHRNA7	3.73e-08	5	55	3	19118188
Pubmed	Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease.	APP CHRFAM7A CHRNA7	3.73e-08	5	55	3	11404397
Pubmed	Regulation of NMDA receptor trafficking by amyloid-beta.	APP CHRFAM7A CHRNA7	1.30e-07	7	55	3	16025111
Pubmed	Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	38070724
Pubmed	Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	34453977
Pubmed	Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	26999808
Pubmed	Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	27129924
Pubmed	Sensorimotor gating and spatial learning in α7-nicotinic receptor knockout mice.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	23521765
Pubmed	Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	28258105
Pubmed	The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	19344760
Pubmed	Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	29114104
Pubmed	Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	33995108
Pubmed	E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	32552811
Pubmed	Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	24836856
Pubmed	Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	15948184
Pubmed	Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	35678315
Pubmed	Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	12628457
Pubmed	Activation of α-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	25157794
Pubmed	Mesenchymal Stem Cells or Interleukin-6 Improve Episodic Memory of Mice Lacking α7 Nicotinic Acetylcholine Receptors.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	31202708
Pubmed	Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	22246862
Pubmed	Activation of Nicotinic Acetylcholine Receptors Decreases Apoptosis in Human and Female Murine Pancreatic Islets.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	27471776
Pubmed	Targeting α-7 nicotinic acetylcholine receptor in the enteric nervous system: a cholinergic agonist prevents gut barrier failure after severe burn injury.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	22688057
Pubmed	Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	32028688
Pubmed	Activation of α7 Nicotinic Acetylcholine Receptor Ameliorates Zymosan-Induced Acute Kidney Injury in BALB/c Mice.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	30429582
Pubmed	A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	21501254
Pubmed	Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	21368056
Pubmed	Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes.	NOS1 NOS2	2.46e-06	2	55	2	7682706
Pubmed	Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	1400473
Pubmed	The role of nitric oxide synthases in the sleep responses to tumor necrosis factor-alpha.	NOS1 NOS2	2.46e-06	2	55	2	15157956
Pubmed	Effects of ethanol on neutrophil recruitment and lung host defense in nitric oxide synthase I and nitric oxide synthase II knockout mice.	NOS1 NOS2	2.46e-06	2	55	2	10512307
Pubmed	Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	26937017
Pubmed	[Expression of cell adhesion molecule and nitric oxide synthase in nasal mucosa in allergic rhinitis].	NOS1 NOS2	2.46e-06	2	55	2	16780147
Pubmed	Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	36603528
Pubmed	Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	26650489
Pubmed	Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	22848433
Pubmed	Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	16650968
Pubmed	Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	35413868
Pubmed	Inducible-NOS but not neuronal-NOS participate in the acute effect of TNF-alpha on hypothalamic insulin-dependent inhibition of food intake.	NOS1 NOS2	2.46e-06	2	55	2	16876161
Pubmed	Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	24462939
Pubmed	Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	29261717
Pubmed	Amyloid Precursor Protein Haploinsufficiency Preferentially Mediates Brain Iron Accumulation in Mice Transgenic for The Huntington's Disease Mutation.	APP HTT	2.46e-06	2	55	2	28550267
Pubmed	Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	18199426
Pubmed	Stroke-induced activation of the α7 nicotinic receptor increases Pseudomonas aeruginosa lung injury.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	22490926
Pubmed	Dendritic spine alterations in the hippocampus and parietal cortex of alpha7 nicotinic acetylcholine receptor knockout mice.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	23270857
Pubmed	Role of nitric oxide synthase in the development of bone cancer pain and effect of L-NMMA.	NOS1 NOS2	2.46e-06	2	55	2	26648027
Pubmed	Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	18077004
Pubmed	Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	19462340
Pubmed	Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	16923147
Pubmed	NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	11790782
Pubmed	Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	37746145
Pubmed	A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	19631623
Pubmed	Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	15770102
Pubmed	Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	24326163
Pubmed	Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: studies in transgenic mice.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	23811428
Pubmed	Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	20720594
Pubmed	Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	17019565
Pubmed	Dilinoleoylphosphatidylcholine ameliorates scopolamine-induced impairment of spatial learning and memory by targeting alpha7 nicotinic ACh receptors.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	19100751
Pubmed	Activation of the α7 Nicotinic Acetylcholine Receptor Prevents against Microglial-Induced Inflammation and Insulin Resistance in Hypothalamic Neuronal Cells.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	35883638
Pubmed	Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.	NOS1 NOS2	2.46e-06	2	55	2	1379716
Pubmed	Acidic pH increases cGMP accumulation through the OGR1/phospholipase C/Ca(2+)/neuronal NOS pathway in N1E-115 neuronal cells.	GPR68 NOS1	2.46e-06	2	55	2	25025574
Pubmed	beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology.	APP CHRNA7	2.46e-06	2	55	2	10681545
Pubmed	A conserved Val to Ile switch near the heme pocket of animal and bacterial nitric-oxide synthases helps determine their distinct catalytic profiles.	NOS1 NOS2	2.46e-06	2	55	2	14976216
Pubmed	Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	19368846
Pubmed	Alpha7-nicotinic acetylcholine receptors mediate an Abeta(1-42)-induced increase in the level of acetylcholinesterase in primary cortical neurones.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	15009674
Pubmed	Hydroxynorketamine, but not ketamine, acts via α7 nicotinic acetylcholine receptor to control presynaptic function and gene expression.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	38253622
Pubmed	Family-based association study between NOS-I and -IIA polymorphisms and autism spectrum disorders in Korean trios.	NOS1 NOS2	2.46e-06	2	55	2	18563708
Pubmed	The role of dorsal root ganglia alpha-7 nicotinic acetylcholine receptor in complete Freund's adjuvant-induced chronic inflammatory pain.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	34514543
Pubmed	α7 nicotinic acetylcholine receptor (α7nAChR) expression in bone marrow-derived non-T cells is required for the inflammatory reflex.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	22183893
Pubmed	Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	9364063
Pubmed	Evidence suggesting that the mouse sperm acrosome reaction initiated by the zona pellucida involves an alpha7 nicotinic acetylcholine receptor.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	12606407
Pubmed	Genetic variations in CHRNA7 or CHRFAM7 and susceptibility to dementia.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	22300029
Pubmed	GTS-21 ameliorates polymicrobial sepsis-induced hepatic injury by modulating autophagy through α7nAchRs in mice.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	32018068
Pubmed	CHRNA7 and CHRFAM7A mRNAs: co-localized and their expression levels altered in the postmortem dorsolateral prefrontal cortex in major psychiatric disorders.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	26206074
Pubmed	Nicotine elicits prolonged calcium signaling along ventral hippocampal axons.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	24349346
Pubmed	The role of nicotinic acetylcholine receptor (nAChR) α7 subtype in the functional interaction between nicotine and ethanol in mouse cerebellum.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	21143250
Pubmed	Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	16319313
Pubmed	The spinal cord expression of neuronal and inducible nitric oxide synthases and their contribution in the maintenance of neuropathic pain in mice.	NOS1 NOS2	2.46e-06	2	55	2	21179208
Pubmed	Impaired synaptic plasticity in the visual cortex of mice lacking α7-nicotinic receptor subunit.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	25797465
Pubmed	Spontaneous sleep in mice with targeted disruptions of neuronal or inducible nitric oxide synthase genes.	NOS1 NOS2	2.46e-06	2	55	2	12738065
Pubmed	Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	29197398
Pubmed	Cholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	38178134
Pubmed	In hippocampal oriens interneurons anti-Hebbian long-term potentiation requires cholinergic signaling via α7 nicotinic acetylcholine receptors.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	23325242
Pubmed	Glutamatergic synapse formation is promoted by α7-containing nicotinic acetylcholine receptors.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	22649244
Pubmed	Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	17898229
Pubmed	Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	21901321
Pubmed	Dopamine release in prefrontal cortex in response to beta-amyloid activation of alpha7 * nicotinic receptors.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	17935702
Pubmed	Neuronal nicotinic alpha7 receptors modulate early neutrophil infiltration to sites of skin inflammation.	CHRFAM7A CHRNA7	2.46e-06	2	55	2	20624304
Cytoband	3q21.3	RPN1 PLXNA1	1.35e-03	45	55	2	3q21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr16q22	ZNF821 SF3B3 PRMT7	1.40e-03	183	55	3	chr16q22
GeneFamily	Exocyst complex	EXOC6 EXOC6B	1.79e-04	9	41	2	1055
Coexpression	HEVNER_SUBPLATE_PROJECTION_NEURONS	CHRFAM7A PLXNA1 CHRNA7	1.90e-06	12	55	3	MM416
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	PCSK5 EXOC6 ATP1A1 NOS1 PREX2	3.83e-06	191	55	5	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL7A1 SGMS2 PKHD1 ATP1A1 APP	3.83e-06	191	55	5	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	PCSK5 EXOC6 ATP1A1 NOS1 PREX2	3.93e-06	192	55	5	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Mesothelial-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	LVRN ADAMTS3 CPED1 PREX2 CHRNA7	4.57e-06	198	55	5	9b1a58fcf818f9c4ae57bbe99655f0a64fe87df7
ToppCell	10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-CMP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADCY10 NOS1 NOS2 PREX2	4.56e-05	160	55	4	be46daf3b42591768c83062a3bb4820efbf88bec
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PCSK5 EXOC6 NOS1 PREX2	4.79e-05	162	55	4	25bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PCSK5 EXOC6 NOS1 PREX2	6.18e-05	173	55	4	3a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PCSK5 EXOC6 NOS1 PREX2	6.75e-05	177	55	4	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 CHRFAM7A PREX2 CHRNA7	6.75e-05	177	55	4	fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCell	facs-SCAT\|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUOX1 ATP1A1 SLC4A4 PLXNA1	7.21e-05	180	55	4	6c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIA2 ADAM9 PM20D1 SLC4A4	7.68e-05	183	55	4	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 PKHD1 AHR NOS1	7.85e-05	184	55	4	7f6c8912677764d438ab0555faca344d74c2f483
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 CHRFAM7A PREX2 CHRNA7	8.01e-05	185	55	4	4c42bd3cd72f91f4d4ebb849069a03761a2cd662
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 CHRFAM7A PREX2 CHRNA7	8.01e-05	185	55	4	08fad1e3c3cc5f1c3eb6629a49c094b628e75a92
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS3 ATP12A SLC4A4 C4orf54	8.01e-05	185	55	4	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 PKHD1 AHR NOS1	8.35e-05	187	55	4	85f1678338a47d91e296f0620d4887f057eb7e70
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SGMS2 PKHD1 ATP1A1 NOS1	8.35e-05	187	55	4	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EXOC6 CEACAM16 NOS1 PREX2	8.35e-05	187	55	4	e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DUOX1 PKHD1 ATP1A1 SLC4A4	8.35e-05	187	55	4	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 EXOC6 NLRP1 PREX2	8.52e-05	188	55	4	c2c51c6526defe2600302901159b8abbb58d7595
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 EXOC6 NLRP1 PREX2	8.70e-05	189	55	4	6463890d8dbee4bc198f91628a5f784970de786a
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	PCSK5 MIA2 PKHD1 SLC4A4	8.70e-05	189	55	4	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL7A1 SGMS2 ATP1A1 APP	8.88e-05	190	55	4	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL7A1 SGMS2 ATP1A1 APP	8.88e-05	190	55	4	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 EXOC6 NLRP1 PREX2	9.06e-05	191	55	4	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 EXOC6 NLRP1 PREX2	9.25e-05	192	55	4	56b021c297a21dff357531f21e2464f85186106d
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6B PKHD1 ZSWIM6 SLC4A4	9.25e-05	192	55	4	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 COL7A1 AHR NOS1	9.43e-05	193	55	4	c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP1A1 APP ATP12A SLC4A4	9.82e-05	195	55	4	576142b4e75457c0973051bccc4163bd624496af
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 EXOC6 NLRP1 PREX2	9.82e-05	195	55	4	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP1A1 APP ATP12A SLC4A4	9.82e-05	195	55	4	8f151066ad3ebd9661ea0b733f03c2ce1518f9ad
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP1A1 APP ATP12A SLC4A4	9.82e-05	195	55	4	2a9a36df1dbc4eac77a8ddbe939ec8a8d6c41464
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DUOX1 AHR SLC4A4 NOS2	1.00e-04	196	55	4	b07db4a53ab9be9aad6fae5e45f9547db829d096
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DUOX1 AHR SLC4A4 NOS2	1.00e-04	196	55	4	c366f980cc04abfe1c0c14746c11810c812a42c0
ToppCell	moderate-Epithelial-Secretory\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RPN1 ADAM9 AHR ATP1A1	1.04e-04	198	55	4	7ecce5e266bb08797088cc8f8309e0c7b48df5c9
ToppCell	distal-Endothelial-Artery-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PCSK5 EXOC6 APP NOS1	1.04e-04	198	55	4	f284f59f4ebe55ee132eddfaa2f5d9ecb059654f
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PCSK5 COL7A1 DUOX1 NOS2	1.04e-04	198	55	4	5374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NLRP1 APP SLC4A4 NOS2	1.06e-04	199	55	4	6723287924750a2247a07ab6e561066a97b09771
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ADAMTS3 ADAM9 CPED1 PREX2	1.06e-04	199	55	4	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL7A1 PKHD1 ATP1A1 APP	1.06e-04	199	55	4	2e7f517c0444b4f29ff11c26ab32e9cc0f7e99ef
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL7A1 ADAMTS3 PKHD1 ATP1A1	1.06e-04	199	55	4	3cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	AHR APP BIRC6 PREX2	1.08e-04	200	55	4	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-PCDH20-L1-2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CPED1 CHRFAM7A PREX2 CHRNA7	1.08e-04	200	55	4	1d67c5d2c617749b521e70879950dea2c9d076d6
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Artery\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	PCSK5 EXOC6 NOS1 PREX2	1.08e-04	200	55	4	34b279804475ea58fbb052b96f44128c082627a9
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_1-CASC6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 CHRFAM7A PREX2 CHRNA7	1.08e-04	200	55	4	1d397ad55f0f7a7dd72aa5a3331d2e0db07f0d39
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	PCSK5 IGSF9B SLC4A4 CPED1	1.08e-04	200	55	4	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Artery\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PCSK5 EXOC6 NOS1 PREX2	1.08e-04	200	55	4	8552cc7a439449b30b59760c3e8667217b9852b5
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL7A1 PKHD1 ATP1A1 APP	1.08e-04	200	55	4	ae91dc047dc80560ba298d8d21a772154fa2775d
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Artery\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PCSK5 EXOC6 ATP1A1 PREX2	1.08e-04	200	55	4	b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Artery-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PCSK5 EXOC6 NOS1 PREX2	1.08e-04	200	55	4	45c08f1befe78553bbadcc2fcffb6138306638f3
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PCSK5 APP SLC4A4 CPED1	1.08e-04	200	55	4	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	PCSK5 EXOC6 ATP1A1 PREX2	1.08e-04	200	55	4	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Artery\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PCSK5 EXOC6 ATP1A1 PREX2	1.08e-04	200	55	4	ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_1-CASC6-L2-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 CHRFAM7A PREX2 CHRNA7	1.08e-04	200	55	4	8576906df19ea1383e2221709b3b309b1bbba28d
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-PCDH20\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CPED1 CHRFAM7A PREX2 CHRNA7	1.08e-04	200	55	4	26c7f2b0afe9e50f2a5c43918ad8e91d7553b72c
ToppCell	Control-B_naive-4\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PCSK5 SGMS2 KIF14	3.97e-04	116	55	3	35d471c8dbf408d0be3837c428d9c2a73c805a6f
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Hpgd\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADCY10 PCSK5 KIF14	5.06e-04	126	55	3	9b04ca8a46cc30119baf6ef27711a0b2a6b4a0c9
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)\|Striatum / BrainAtlas - Mouse McCarroll V32	GPR68 IGSF9B NOS2	5.30e-04	128	55	3	7e3f5cea91af005f08d8e9340fb8630bf1c887c3
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6\|Striatum / BrainAtlas - Mouse McCarroll V32	GPR68 IGSF9B NOS2	5.30e-04	128	55	3	a876303c852db2af9418d1a1711d7c950805018a
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)-\|Striatum / BrainAtlas - Mouse McCarroll V32	GPR68 IGSF9B NOS2	5.30e-04	128	55	3	388062f840fd04cb8087f27a9a78e7a192920e3e
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADCY10 ADAMTS3 NOS1	5.79e-04	132	55	3	ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTS3 SLC4A4 NOS1	7.46e-04	144	55	3	b622b605f7ec6083ec06c8ea0fd171e07c52f3de
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PCSK5 AHR ATP12A	7.46e-04	144	55	3	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SGMS2 DNAJB5 CHRFAM7A	7.61e-04	145	55	3	f6ba6cf0c8d0ee87a7904485b27eb9261fcb6edd
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY10 PKHD1 ATP12A	7.61e-04	145	55	3	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SGMS2 ATP1A1 SLC4A4	7.61e-04	145	55	3	47a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	AKAP14 SLC4A4 C4orf54	7.92e-04	147	55	3	b66ccc710b3c04f6fc7fed69f3c892fc110e98fc
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADCY10 COL7A1 CPED1	8.39e-04	150	55	3	7a9d6a7ff8000e9a061e1b586e4c258cc91a2a09
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADCY10 COL7A1 CPED1	8.39e-04	150	55	3	e5b843cb2bc847f6cab4cbec0a2a6a72fac50fee
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CEACAM16 NOS1 PREX2	8.39e-04	150	55	3	4f31867cb85253ff6d22f3b02ef972a42cb41123
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 NFKB2 CHRFAM7A	8.72e-04	152	55	3	88a810d41edb5a917c23cb5ba5a387227e1312cb
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IGSF9B NOS1 PREX2	8.89e-04	153	55	3	61fe71e32fc9c8cad875bc087aad0b0ff680bf45
ToppCell	PND28-Immune-Immune_Myeloid-DC-maDC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL7A1 GPR68 NFKB2	8.89e-04	153	55	3	b03375c54aa701817c0fc2c3fef32b870169e697
ToppCell	PND28-Immune-Immune_Myeloid-DC-maDC-maDC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL7A1 GPR68 NFKB2	8.89e-04	153	55	3	18bd770a18e642581a6df144d47184c1ac383713
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 EXOC6 NLRP1	9.06e-04	154	55	3	e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCell	367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ATP12A SLC4A4 CPED1	9.23e-04	155	55	3	8dab23aad905cc35a35643baa0554acb3f6fe6c8
ToppCell	367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ATP12A SLC4A4 CPED1	9.23e-04	155	55	3	42533beaded07068f00540de704de07e4f19abcf
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGMS2 PM20D1 SLC4A4	9.40e-04	156	55	3	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PCSK5 SLC4A4 CPED1	9.57e-04	157	55	3	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Club\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	ATP12A SLC4A4 CHRNA7	9.75e-04	158	55	3	03281e87780e3bacd089903383c016d03c373bf7
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PFDN5 ATP1A1 APP	9.75e-04	158	55	3	132024892185ab1a8293196b11c290884442564d
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-basal_intermediate_\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL7A1 DUOX1 ATP12A	9.75e-04	158	55	3	98712ed7e8e65e8c5ff9318cf0e0a04e271a055d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DUOX1 PKHD1 ATP1A1	9.93e-04	159	55	3	e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	RPN1 AKAP14 DNAJB5	1.01e-03	160	55	3	6d941e584360975e1fdbb2fc67af8e31f18759d8
ToppCell	facs-Heart-RV-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 AKAP14 IGSF9B	1.01e-03	160	55	3	c1d03c0ac9c12615a06499209fcdf18e9b6f1fba
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGMS2 SLC4A4 FBXO21	1.01e-03	160	55	3	c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCell	facs-Heart-RV-24m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 AKAP14 IGSF9B	1.01e-03	160	55	3	41d6c811c445c0ba9b6a2deb10a3b6b793172582
ToppCell	metastatic_Brain-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	PCSK5 COL7A1 ATP12A	1.03e-03	161	55	3	e6e294b4ba911c1327664f1a0f93207096c6de03
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY10 PKHD1 ATP12A	1.05e-03	162	55	3	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	TCGA-Kidney-Solid_Tissue_Normal\|TCGA-Kidney / Sample_Type by Project: Shred V9	ATP1A1 ATP12A C4orf54	1.05e-03	162	55	3	65549ffdbfe8619693345db78e6ddbdde7b742c9
ToppCell	TCGA-Kidney-Solid_Tissue_Normal-Kidney-Kidney_normal_tissue\|TCGA-Kidney / Sample_Type by Project: Shred V9	ATP1A1 ATP12A C4orf54	1.05e-03	162	55	3	a0367e9af78e4699b9d89d3e0597589e644f844c
ToppCell	TCGA-Kidney-Solid_Tissue_Normal-Kidney\|TCGA-Kidney / Sample_Type by Project: Shred V9	ATP1A1 ATP12A C4orf54	1.05e-03	162	55	3	d007ec42d6458431f6c490df61de7a9caef857f0
ToppCell	Control-MAIT\|World / Disease group and Cell class	DUOX1 PM20D1 SLC4A4	1.07e-03	163	55	3	0ca4b835936b4f82217cbe57210c1dd90986c1d0
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FICD RIOK1 GPR68	1.09e-03	164	55	3	950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCell	droplet-Liver-nan-3m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FICD RIOK1 GPR68	1.09e-03	164	55	3	bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FICD RIOK1 GPR68	1.09e-03	164	55	3	c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNG3 KIF14 ATP12A	1.09e-03	164	55	3	25758fb8112baf296264122d5d4121f1ebb3d0fa
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNG3 KIF14 ATP12A	1.09e-03	164	55	3	1642a67c66eeb77a218e7814e3cfe517d9822955
ToppCell	COVID-19-lung-Mesothelial\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTS3 AHR SLC4A4	1.09e-03	164	55	3	83303e2ba52008391b8dc3fae8225ab5bcb20063
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CEACAM16 KIF14 NOS1	1.10e-03	165	55	3	953c8242a81a39ade63ac8e5b34fe58575771746
Drug	ebselen	DUOX1 ADAM9 NFKB2 NLRP1 PFDN5 NOS1 NOS2	2.51e-08	131	54	7	CID000003194
Drug	NSC-6354	DUOX1 NFKB2 NLRP1 NOS1 NOS2 STAT3	8.15e-08	92	54	6	CID000221534
Drug	haloperidol	ADCY10 NFKB2 NLRP1 PFDN5 CHRFAM7A NOS1 NOS2 CHRNA7 HTT	3.40e-07	394	54	9	CID000003559
Drug	Dirithromycin [62013-04-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A	ZNF821 DUOX1 GPR68 NFKB2 SLC4A4 FBXO21 NOS1	4.39e-07	199	54	7	7446_UP
Drug	AP-5	NLRP1 ZSWIM6 CHRFAM7A NOS1 NOS2 CHRNA7	5.81e-07	128	54	6	CID000001216
Drug	MnTM-2-PyP5+	DUOX1 NLRP1 NOS1 NOS2	9.67e-07	32	54	4	CID000153503
Drug	Sulcrate	NLRP1 APP ATP12A CHRFAM7A NOS2 CHRNA7	1.36e-06	148	54	6	CID006398525
Drug	cloricromene	APP ATP12A CHRFAM7A NOS2 CHRNA7	1.98e-06	87	54	5	CID000068876
Drug	N-methyl-DL-aspartic acid	CACNG3 NFKB2 NLRP1 ZSWIM6 APP CHRFAM7A NOS1 NOS2 CHRNA7 HTT	2.77e-06	655	54	10	CID000004376
Drug	carbachol	CACNG3 ADCY10 NFKB2 AHR APP SLC4A4 CHRFAM7A NOS1 NOS2 CHRNA7	4.28e-06	688	54	10	CID000002551
Drug	AC1L1GI5	DUOX1 NOS1 NOS2 STAT3	4.67e-06	47	54	4	CID000003693
Drug	N-acetylcysteine	COL7A1 DUOX1 NFKB2 AHR NLRP1 NOS1 NOS2 STAT3 HTT	5.00e-06	546	54	9	CID000000581
Drug	N-Omega-Propyl-L-Arginine	NOS1 NOS2	5.52e-06	2	54	2	DB02644
Drug	Cytidine Triphosphate	AHR APP	5.52e-06	2	54	2	ctd:D003570
Drug	tiliroside	AHR APP	5.52e-06	2	54	2	ctd:C052083
Drug	N-(1-azabicyclo(2.2.2)oct-3-yl)furo(2,3-c)pyridine-5-carboxamide	APP CHRNA7	5.52e-06	2	54	2	ctd:C513163
Drug	N-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine	NOS1 NOS2	5.52e-06	2	54	2	DB03449
Drug	MEK1/2 inhibitor	NFKB2 AHR NLRP1 SLC4A4 NOS2 STAT3	6.32e-06	193	54	6	CID009549284
Drug	ramiprilat	NFKB2 APP NOS1 NOS2	8.81e-06	55	54	4	CID005464096
Drug	AC1L1KRE	PFDN5 NOS1 NOS2	1.40e-05	20	54	3	CID000005622
Drug	Gsh-Et	NLRP1 NOS2	1.65e-05	3	54	2	CID003036127
Drug	5-methyl-1,10-phenanthroline	AHR APP	1.65e-05	3	54	2	ctd:C017518
Drug	3-Bromo-7-Nitroindazole	NOS1 NOS2	1.65e-05	3	54	2	DB01997
Drug	N-(3-(Aminomethyl)Benzyl)Acetamidine	NOS1 NOS2	1.65e-05	3	54	2	DB02044
Drug	diphenyleneiodonium	DUOX1 RPN1 NFKB2 NLRP1 NOS1 NOS2	1.80e-05	232	54	6	CID000003101
Drug	NF-kappaB activation inhibitor	NFKB2 NOS2 STAT3	1.88e-05	22	54	3	CID000509554
Drug	verapamil	CACNG3 ADCY10 ATP1A1 BIRC6 CHRFAM7A NOS1 NOS2 CHRNA7	1.90e-05	490	54	8	CID000002520
Drug	paramethoxyphenyl-acetyl dehydroalanine	APP ATP12A CHRFAM7A CHRNA7	2.18e-05	69	54	4	CID000130300
Drug	acetylcholine	DUOX1 AHR NLRP1 CHRFAM7A NOS1 NOS2 CHRNA7	2.22e-05	361	54	7	CID000000187
Drug	SP600125	GPR68 NFKB2 AHR NLRP1 NOS1 NOS2 STAT3	2.26e-05	362	54	7	CID000008515
Drug	tacrine	APP CHRFAM7A NOS1 NOS2 CHRNA7	2.33e-05	144	54	5	CID000001935
Drug	anabaseine	APP CHRFAM7A CHRNA7	2.46e-05	24	54	3	CID000018985
Drug	2-phenylimidazole	PFDN5 NOS1 NOS2	2.46e-05	24	54	3	CID000069591
Drug	triflusal	NFKB2 NOS1 NOS2	2.80e-05	25	54	3	CID000009458
Drug	Nicorette	NFKB2 NLRP1 APP CHRFAM7A NOS1 NOS2 CHRNA7 STAT3	3.27e-05	529	54	8	CID000000942
Drug	(6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin	NOS1 NOS2	3.30e-05	4	54	2	DB02692
Drug	3-O-methylsphingomyelin	APP NOS2	3.30e-05	4	54	2	ctd:C508074
Drug	praeruptorin E	NOS2 STAT3	3.30e-05	4	54	2	ctd:C036455
Drug	N-Omega-Hydroxy-L-Arginine	NOS1 NOS2	3.30e-05	4	54	2	DB03144
Drug	ellagic acid	PCSK5 NFKB2 NLRP1 NOS2 STAT3	3.52e-05	157	54	5	CID005281855
Drug	Selenic Acid	AHR NOS1 STAT3	3.54e-05	27	54	3	ctd:D064586
Drug	Thioglycolates	GPR68 NOS1 NOS2	3.54e-05	27	54	3	ctd:D013864
Drug	ketamine	NFKB2 CHRFAM7A NOS1 NOS2 CHRNA7 STAT3	3.57e-05	262	54	6	CID000003821
Drug	homocysteine	NFKB2 NLRP1 ATP12A CHRFAM7A NOS2 CHRNA7	3.88e-05	266	54	6	CID000000778
Drug	MPTP-HCl	NLRP1 CHRFAM7A NOS1 NOS2 CHRNA7	4.09e-05	162	54	5	CID000001388
Drug	3,3',4,5'-tetrahydroxystilbene	AHR APP NOS2 STAT3	4.11e-05	81	54	4	ctd:C041525
Drug	trimethaphan	ATP1A1 CHRFAM7A NOS2 CHRNA7	4.11e-05	81	54	4	CID000023576
Drug	S-nitrosoacetylcysteine	NLRP1 NOS1 NOS2	4.41e-05	29	54	3	CID000122058
Drug	Melitten	NOS1 NOS2 CHRNA7 STAT3	4.52e-05	83	54	4	ctd:D008555
Drug	aluminum sulfate	ADAM9 APP NOS1	4.89e-05	30	54	3	ctd:C041524
Drug	methylenedioxydimethylamphetamine	NLRP1 CHRFAM7A CHRNA7	4.89e-05	30	54	3	CID000551630
Drug	L-thiocitrulline	NLRP1 NOS1 NOS2	4.89e-05	30	54	3	CID002733514
Drug	DCFH-DA	DUOX1 NLRP1 NOS1 NOS2	5.20e-05	86	54	4	CID000104913
Drug	WHI-P154	NLRP1 NOS2 STAT3	5.41e-05	31	54	3	CID000003795
Drug	deuteroporphyrin	PFDN5 NOS1 NOS2	5.41e-05	31	54	3	CID000067973
Drug	Thiourea	APP NOS1 NOS2	5.41e-05	31	54	3	ctd:D013890
Drug	AC1L1JK6	APP CHRFAM7A CHRNA7	5.41e-05	31	54	3	CID000005077
Drug	nogalonic acid methyl ester	NLRP1 PFDN5 NOS1 NOS2	5.44e-05	87	54	4	CID000443820
Drug	4-(nitroxy)butanoic acid 4-acetylaminophenyl ester	NOS1 NOS2	5.50e-05	5	54	2	ctd:C478738
Drug	C15H20O3	ADAMTS3 NFKB2 NLRP1 NOS2 STAT3	5.91e-05	175	54	5	CID000004692
Drug	lactacystin	AHR ATP1A1 APP NOS2	6.48e-05	91	54	4	ctd:C067713
Drug	methyllycaconitine	APP CHRNA7 STAT3	6.54e-05	33	54	3	ctd:C054634
Drug	FK 409	PFDN5 NOS1 NOS2	6.54e-05	33	54	3	CID006413529
Drug	U0126	GPR68 NFKB2 AHR NLRP1 NOS1 NOS2 STAT3	6.72e-05	430	54	7	CID000005637
Drug	MK-801	NFKB2 NLRP1 CHRFAM7A NOS1 NOS2 CHRNA7	7.02e-05	296	54	6	CID000001207
Drug	lithium chromate	NFKB2 ATP1A1 APP SLC4A4 CHRFAM7A CHRNA7	7.02e-05	296	54	6	CID000026627
Drug	AC1NMVIZ	NLRP1 NOS1 NOS2	7.16e-05	34	54	3	CID005057842
Drug	17-AAG; Up 200; 1uM; HL60; HT_HG-U133A	PCSK5 COL7A1 ATP12A SLC4A4 NOS1	7.30e-05	183	54	5	6185_UP
Drug	dihydroethidium	DUOX1 NLRP1 NOS1 NOS2	7.67e-05	95	54	4	CID000128682
Drug	vitamin E	NFKB2 NLRP1 PFDN5 CHRFAM7A NOS2 CHRNA7 HTT	7.87e-05	441	54	7	CID000002116
Drug	apocynin	DUOX1 NFKB2 NLRP1 NOS1 NOS2	7.88e-05	186	54	5	CID000002214
Drug	Y-27632	COL7A1 DUOX1 ADAM9 PFDN5 APP NOS1 NOS2	8.21e-05	444	54	7	CID000005711
Drug	N-nitroso-L-arginine	NOS1 NOS2	8.23e-05	6	54	2	CID000127762
Drug	NapNa	NOS1 NOS2	8.23e-05	6	54	2	CID000128726
Drug	1-hexacosanol	NOS1 NOS2	8.23e-05	6	54	2	ctd:C051942
Drug	Naphtho[2,3-a]pyrene	AHR APP	8.23e-05	6	54	2	CID000009137
Drug	dimethylfumarate	NLRP1 APP	8.23e-05	6	54	2	CID000010262
Drug	1 Tc1	DUOX1 NLRP1 NOS1 NOS2	9.36e-05	100	54	4	CID000083786
Drug	nsc25485	NFKB2 PFDN5 ATP1A1 ATP12A SLC4A4 NOS2	9.37e-05	312	54	6	CID000004605
Drug	AC1L1B55	COL7A1 NFKB2 AHR NLRP1 NOS1 NOS2 STAT3	9.44e-05	454	54	7	CID000001287
Drug	Iodixanol [92339-11-2]; Down 200; 2.6uM; MCF7; HT_HG-U133A	COL7A1 MIA2 FBXO21 CPED1 PREX2	9.61e-05	194	54	5	4848_DN
Drug	halothane	CACNG3 AHR CHRFAM7A NOS1 NOS2 CHRNA7	9.71e-05	314	54	6	CID000003562
Drug	diethyldithiocarbamate	NFKB2 NLRP1 NOS1 NOS2	9.73e-05	101	54	4	CID000008987
Drug	Phenacetin [62-44-2]; Down 200; 22.4uM; PC3; HT_HG-U133A	MIA2 EXOC6B APP SLC4A4 CPED1	9.85e-05	195	54	5	3992_DN
Drug	Ciprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; MCF7; HT_HG-U133A	MIA2 NFKB2 APP SLC4A4 PLXNA1	9.85e-05	195	54	5	1522_DN
Drug	amiloride	CACNG3 PFDN5 ATP1A1 SLC4A4 CHRFAM7A CHRNA7	9.88e-05	315	54	6	CID000016230
Drug	(S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; HL60; HT_HG-U133A	ZNF821 NLRP1 DNAJB5 SLC4A4 PLXNA1	1.01e-04	196	54	5	2961_UP
Drug	Indoprofen [31842-01-0]; Up 200; 14.2uM; HL60; HT_HG-U133A	PCSK5 EXOC6B NLRP1 SLC4A4 NOS1	1.03e-04	197	54	5	3007_UP
Drug	Chlortetracycline hydrochloride [64-72-2]; Down 200; 7.8uM; MCF7; HT_HG-U133A	ZNF821 MIA2 NFKB2 SLC4A4 PLXNA1	1.03e-04	197	54	5	1541_DN
Drug	AC1Q5S0Y	SLC4A4 NOS1 NOS2 STAT3	1.05e-04	103	54	4	CID000005650
Drug	Neomycin sulfate [1405-10-3]; Up 200; 4.2uM; PC3; HT_HG-U133A	ZNF821 NFKB2 NLRP1 DNAJB5 SLC4A4	1.06e-04	198	54	5	2066_UP
Drug	Practolol [6673-35-4]; Up 200; 15uM; HL60; HG-U133A	SF3B3 NFKB2 AHR APP PLXNA1	1.06e-04	198	54	5	1587_UP
Drug	Carbamazepine [298-46-4]; Up 200; 17uM; HL60; HT_HG-U133A	NFKB2 NLRP1 APP FBXO21 PLXNA1	1.08e-04	199	54	5	1847_UP
Drug	C070379	NFKB2 NLRP1 SLC4A4 NOS1 NOS2	1.08e-04	199	54	5	CID003034747
Drug	1-phenylimidazole	AHR NOS1 NOS2	1.08e-04	39	54	3	CID000081595
Drug	Cefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; PC3; HT_HG-U133A	SF3B3 KIF14 NLRP1 SLC4A4 CPED1	1.11e-04	200	54	5	5830_UP
Drug	phentolamine	ADCY10 CHRFAM7A NOS1 NOS2 CHRNA7	1.11e-04	200	54	5	CID000005775
Drug	potassium	CACNG3 NFKB2 PFDN5 ATP1A1 ATP12A SLC4A4 CHRFAM7A NOS1 NOS2 CHRNA7	1.12e-04	1008	54	10	CID000000813
Drug	Superoxides	APP NOS1 NOS2 HTT	1.13e-04	105	54	4	ctd:D013481
Drug	Toxins, Biological	COL7A1 ADAM9 NFKB2 AHR DNAJB5 NOS1 NOS2 STAT3	1.14e-04	632	54	8	ctd:D014118
Disease	Seizures	ATP1A1 APP KMT2E NOS1 NOS2 CHRNA7	2.61e-06	218	53	6	C0036572
Disease	Congenital exomphalos	PCSK5 CHRNA7	3.17e-06	2	53	2	C1306503
Disease	Congenital omphalocele	PCSK5 CHRNA7	3.17e-06	2	53	2	C0795690
Disease	colon adenocarcinoma (is_marker_for)	PCSK5 NOS2 STAT3	1.22e-05	25	53	3	DOID:234 (is_marker_for)
Disease	lissencephaly (implicated_via_orthology)	WDR75 NOS1 NOS2	1.55e-05	27	53	3	DOID:0050453 (implicated_via_orthology)
Disease	level of Sphingomyelin (d38:1) in blood serum	ADAMTS3 NLRP1 SLC4A4	2.15e-05	30	53	3	OBA_2045180
Disease	level of Sphingomyelin (d40:1) in blood serum	ADAMTS3 NLRP1 SLC4A4	2.62e-05	32	53	3	OBA_2045182
Disease	cognitive disorder (implicated_via_orthology)	CHRFAM7A CHRNA7	4.73e-05	6	53	2	DOID:1561 (implicated_via_orthology)
Disease	rheumatoid arthritis (biomarker_via_orthology)	CHRFAM7A CHRNA7	4.73e-05	6	53	2	DOID:7148 (biomarker_via_orthology)
Disease	Memory Loss	APP CHRNA7 STAT3	6.42e-05	43	53	3	C0751295
Disease	Age-Related Memory Disorders	APP CHRNA7 STAT3	6.42e-05	43	53	3	C0751292
Disease	Memory Disorder, Spatial	APP CHRNA7 STAT3	6.42e-05	43	53	3	C0751294
Disease	Memory Disorder, Semantic	APP CHRNA7 STAT3	6.42e-05	43	53	3	C0751293
Disease	Memory Disorders	APP CHRNA7 STAT3	6.42e-05	43	53	3	C0025261
Disease	familial hemiplegic migraine (implicated_via_orthology)	ATP1A1 ATP12A	6.61e-05	7	53	2	DOID:0060178 (implicated_via_orthology)
Disease	Memory impairment	APP CHRNA7 STAT3	6.88e-05	44	53	3	C0233794
Disease	Silicosis	AHR NOS2	1.13e-04	9	53	2	C0037116
Disease	Necrosis	AHR APP NOS2	1.34e-04	55	53	3	C0027540
Disease	Atrophic	AHR STAT3	1.41e-04	10	53	2	C0333641
Disease	Atherogenesis	AHR NOS2 STAT3	1.66e-04	59	53	3	C1563937
Disease	Atherosclerosis	AHR NOS2 STAT3	1.66e-04	59	53	3	C0004153
Disease	Depressive disorder	APP NOS1 NOS2 STAT3 HTT	1.70e-04	289	53	5	C0011581
Disease	nervous system disease (implicated_via_orthology)	ATP1A1 ATP12A	2.07e-04	12	53	2	DOID:863 (implicated_via_orthology)
Disease	nicotine dependence (implicated_via_orthology)	CHRFAM7A CHRNA7	2.07e-04	12	53	2	DOID:0050742 (implicated_via_orthology)
Disease	retinopathy of prematurity (biomarker_via_orthology)	NOS1 NOS2	2.07e-04	12	53	2	DOID:13025 (biomarker_via_orthology)
Disease	Neurobehavioral Manifestations	NOS1 CHRNA7	2.07e-04	12	53	2	C0525041
Disease	epilepsy (implicated_via_orthology)	ATP1A1 ATP12A NOS1 NOS2	2.13e-04	163	53	4	DOID:1826 (implicated_via_orthology)
Disease	schizophrenia (implicated_via_orthology)	CHRFAM7A NOS1 CHRNA7	2.52e-04	68	53	3	DOID:5419 (implicated_via_orthology)
Disease	Tobacco Dependence	AHR CHRNA7	2.84e-04	14	53	2	C0040332
Disease	Nicotine Dependence	AHR CHRNA7	2.84e-04	14	53	2	C0028043
Disease	Manganese Poisoning	NOS2 HTT	2.84e-04	14	53	2	C0677050
Disease	Nicotine Use Disorder	AHR CHRNA7	2.84e-04	14	53	2	C0376384
Disease	hepatic encephalopathy (biomarker_via_orthology)	NOS1 NOS2	3.27e-04	15	53	2	DOID:13413 (biomarker_via_orthology)
Disease	Nerve Degeneration	APP NOS1 CHRNA7	4.54e-04	83	53	3	C0027746
Disease	impotence (biomarker_via_orthology)	NOS1 NOS2	7.15e-04	22	53	2	DOID:1875 (biomarker_via_orthology)
Disease	Splenomegaly	AHR APP	7.15e-04	22	53	2	C0038002
Disease	hypertension (biomarker_via_orthology)	APP SLC4A4 NOS1 NOS2	7.43e-04	227	53	4	DOID:10763 (biomarker_via_orthology)
Disease	Visual seizure	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0270824
Disease	Epileptic drop attack	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0270846
Disease	Generalized seizures	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0234533
Disease	Clonic Seizures	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0234535
Disease	Vertiginous seizure	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0422855
Disease	Gustatory seizure	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0422854
Disease	Seizures, Somatosensory	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0422850
Disease	Olfactory seizure	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0422853
Disease	Seizures, Auditory	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0422852
Disease	Generalized Absence Seizures	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C4505436
Disease	Convulsive Seizures	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0751494
Disease	Seizures, Sensory	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0751496
Disease	pancreatic cancer (is_marker_for)	ADAM9 AHR NOS2	8.05e-04	101	53	3	DOID:1793 (is_marker_for)
Disease	Jacksonian Seizure	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0022333
Disease	Non-epileptic convulsion	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0751056
Disease	Atonic Absence Seizures	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0751123
Disease	Complex partial seizures	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0149958
Disease	Single Seizure	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C0751110
Disease	Epileptic Seizures	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C4317109
Disease	Nonepileptic Seizures	NOS1 NOS2 CHRNA7	8.05e-04	101	53	3	C3495874
Disease	Tonic Seizures	NOS1 NOS2 CHRNA7	8.29e-04	102	53	3	C0270844
Disease	Weight Gain	AHR APP FBXO21	8.29e-04	102	53	3	C0043094
Disease	Absence Seizures	NOS1 NOS2 CHRNA7	8.29e-04	102	53	3	C4316903
Disease	Convulsions	NOS1 NOS2 CHRNA7	8.29e-04	102	53	3	C4048158
Disease	Seizures, Focal	NOS1 NOS2 CHRNA7	8.77e-04	104	53	3	C0751495
Disease	Myoclonic Seizures	NOS1 NOS2 CHRNA7	8.77e-04	104	53	3	C4317123
Disease	Tonic - clonic seizures	NOS1 NOS2 CHRNA7	8.77e-04	104	53	3	C0494475
Disease	Colitis	AHR NOS2	9.25e-04	25	53	2	C0009319
Disease	JT interval	RIOK1 DNAJB5 SLC4A4 STAT3	1.03e-03	248	53	4	EFO_0007885
Disease	Fever	NOS1 STAT3	1.08e-03	27	53	2	C0015967
Disease	Alzheimer's disease (is_marker_for)	APP NOS1 NOS2 CHRNA7	1.18e-03	257	53	4	DOID:10652 (is_marker_for)
Disease	level of Sphingomyelin (d42:2) in blood serum	ADAMTS3 SLC4A4	1.25e-03	29	53	2	OBA_2045183
Disease	sugar consumption measurement	PKHD1 KIF14 IGSF9B	1.32e-03	120	53	3	EFO_0010158
Disease	Inflammation	AHR NOS2 STAT3	1.56e-03	127	53	3	C0021368
Disease	Alzheimer's disease (is_implicated_in)	APP NOS1 STAT3	1.74e-03	132	53	3	DOID:10652 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SDVIHQSVYELIHTE	AHR	151	P35869
IVVSYVGDHQALVHR	AKAP14	151	Q86UN6
VVHELRVSLEEIYHG	DNAJB5	171	O75953
THVTETIGVFQLHII	nan	196	Q9N2J8
ISAVIESVTFLVHHY	BIRC6	2856	Q9NR09
QHILTQHGYTVVIAE	CPED1	116	A4D0V7
KQYTSIHHGVVEVDA	APP	726	P05067
QTEVGYGHVQVHEIL	CEACAM16	116	Q2WEN9
IVGVVAVHIYIEKHQ	CACNG3	191	O60359
VGHTVRHEYTVIGQK	ADCY10	396	Q96PN6
KTLISYVVSHEIGHQ	LVRN	406	Q6Q4G3
LSVVVTVIVLQYHHH	CHRNA7	306	P36544
IQHEVVEEYSHLFTI	PM20D1	96	Q6GTS8
TVLHSVGHVVNVYLF	DUOX1	1141	Q9NRD9
IHLTVAVVTYHTRDG	NOS2	921	P35228
GAVGYLVQHTLEHIE	FBXO21	466	O94952
VGSYESRVTHIVHQE	KIF14	1556	Q15058
IEIEHFVHIVAGVAV	ATP12A	301	P54707
AEIEHFIHIITGVAV	ATP1A1	286	P05023
HIYHTVAIEGNTLTL	FICD	226	Q9BVA6
LHDVEHVLIDVGTGY	PFDN5	76	Q99471
HVNYLEHVVVRITIT	PCSK5	501	Q92824
LTHLVVHEQTGEVYV	PLXNA1	51	Q9UIW2
VTSVVLLYHRVHPEE	NLRP1	1231	Q9C000
EVRHEIQDGTIHLYI	KMT2E	416	Q8IZD2
QIVGFFVVEDHILHT	EXOC6B	346	Q9Y2D4
FVVEDHILHTTQGLV	EXOC6B	351	Q9Y2D4
LSVVVTVIVLQYHHH	CHRFAM7A	216	Q494W8
TQIVGFFVVEDHILH	EXOC6	336	Q8TAG9
DHILHVTQGLVTRAY	EXOC6	346	Q8TAG9
YDIVHLEHETLVLVV	NOS1	796	P29475
IYHDESLGVHINVVL	ADAMTS3	291	O15072
AEQLVQVYELTLHHT	HTT	351	P42858
VLAHHLGVEQVFTVE	PRMT7	416	Q9NVM4
VSYVIQAEGKEHIIH	ADAM9	66	Q13443
DTEYTVHVRAHVAGV	COL7A1	746	Q02388
HYITTHEIQLSEVEQ	C4orf54	366	D6RIA3
THVVTTVENGYLHQD	IER5L	261	Q5T953
THHLLADVYGVTEVL	PHF20L1	771	A8MW92
ERTIHSYQGQIISHE	MIA2	1051	Q96PC5
DHTIHQTLAPVVYVT	GPR68	16	Q15743
AHLGYSVVAINHIVD	RPP30	26	P78346
GVYIIDVSQSVEHDH	RIOK1	336	Q9BRS2
VSHVKDSEGVELHVY	TEDDM1	116	Q5T9Z0
LVEQHIQDIVVHYTF	RPN1	416	P04843
VSIHSQGVDLHIQYL	PKHD1	1181	P08F94
ILVAHEHYTIDVIIA	SGMS2	266	Q8NHU3
VTLIVIGQSSYHHIE	PRXL2C	91	Q7RTV5
YSIQGEAVHTTHLLV	IGSF9B	211	Q9UPX0
VYSTVTEECVHILHG	WDR75	41	Q8IWA0
LHLITFETEVYHQGL	STAT3	436	P40763
EHVSLTVDNVHLEYG	PREX2	806	Q70Z35
HKANTLVYHVVGVDV	SF3B3	161	Q15393
VQYLITVHHTEVLPT	ZSWIM6	311	Q9HCJ5
GDSHYEIEIVHISTV	ZFYVE21	151	Q9BQ24
EQLIAHVYQHTAAVV	ZNF821	131	O75541
EEVEGHHTIYIGVHV	SLC4A4	21	Q9Y6R1
TSVIEQIVYVIHHAQ	NFKB2	501	Q00653
QIVYVIHHAQDLGVV	NFKB2	506	Q00653