Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Pubmed

Human transcription factor protein interaction networks.

MBTD1 CAD ZEB1 HIVEP1 EP400 WDR33 MARS1 MBNL1 UTP14A ETV3 TFIP11 RBM28 CUL7 MIDEAS CXXC1 CIC SDAD1 PHF21A TAB3 HNRNPL C3P1 KMT2D RESF1 CHD5 RLIM SEC16A CCAR1 ANKRD17 NKX2-5 HELZ ASXL2 EIF3B SUFU PRRC2B SYMPK

1.82e-1414291813535140242
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TPR FILIP1 RANBP2 ZEB1 HIVEP1 EP400 USP24 AAK1 TFIP11 CIC MYOF KMT2D GZMB SEC16A CCAR1 ANKRD17 HELZ TIMELESS EIF3B SUZ12 SYMPK

8.11e-107741812115302935
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

EFL1 RANBP2 ACOT8 CAD VEZT PDLIM7 MCAM CUL7 ANKLE2 CIC SDAD1 TAB3 HNRNPL KMT2D TOX4 STXBP3 PTPRS SEC16A HELZ TANC1 SUFU CTDSPL PRRC2B SYMPK

1.38e-0910491812427880917
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

MBTD1 ZEB1 HIVEP1 EP400 PCLO APC PHF21A KMT2D RESF1 SEC16A CIZ1 BICRAL SUZ12 SUFU SMCR8

3.21e-093981811535016035
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

TPR EXOSC10 CAD EP400 WDR33 PDLIM7 USP24 TFIP11 SHTN1 MIDEAS TAB3 KMT2D TOX4 SEC16A CIZ1 PRRC2B SYMPK

5.26e-095491811738280479
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TPR RANBP2 ZEB1 HIVEP1 USP24 APC SHTN1 CIC PHF21A KMT2D TOX4 RESF1 USO1 SEC16A ANKRD17

6.19e-094181811534709266
Pubmed

A human MAP kinase interactome.

TPR RANBP2 HIVEP1 APC PLEKHA6 ARHGEF11 CBLB MIDEAS CIC HIPK3 TOX4 USF3 ARHGAP31 ANKRD17 HELZ BICRAL

6.42e-094861811620936779
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

RANBP2 CAD WDR33 MBNL1 UTP14A AAK1 ETV3 TFIP11 RBM28 MIDEAS HNRNPL USO1 HELZ SUZ12

1.04e-083701811422922362
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

TPR RANBP2 EXOSC10 EP400 MARS1 UTP14A AAK1 TFIP11 SHTN1 PICALM CIC PHF21A USP8 TOX4 SEC16A CIZ1 ANKRD17 HELZ SMCR8 JPT2 PRRC2B

2.15e-089341812133916271
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MBTD1 ACOT8 EP400 VWA8 VEZT E2F2 SCEL CUL7 C11orf16 PHF21A RESF1 HMCN2 CHD5 SEC16A CIZ1 FOXL2NB ANKRD17 HELZ BICRAL TANC1 SUZ12 CDH15 PRRC2B

2.17e-0811161812331753913
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

TPR MBTD1 RANBP2 EP400 POLE UTP14A CUL7 MDM4 CIC PHF21A HNRNPL KMT2D USO1 DMKN ANKRD17 NKX2-5 ASXL2 SUFU NOTCH3 SYMPK

2.60e-088571812025609649
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

TPR RANBP2 EXOSC10 HIVEP1 EP400 WDR33 MBNL1 UTP14A TFIP11 RBM28 MIDEAS PICALM CIC HNRNPL TOX4 SEC16A CIZ1 CCAR1 NKX2-5 SPATA22 SYMPK

3.09e-089541812136373674
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

STK36 MAGEL2 EP400 PDLIM7 MDM4 PICALM CIC USF3 ARHGAP31 AP5B1 PLCH2 CHD5 NKX2-5 SUFU

6.74e-084301811435044719
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

UNC13B ATMIN STK36 EP400 VWA8 POLE PIEZO1 OBSCN FAM110A ARHGEF11 CIC MYOF KMT2D CELSR2 PTPRS CHD5 SCN8A SEC16A TANC1 SUFU PRRC2B SYMPK

8.21e-0811051812235748872
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

MBTD1 CAD HIVEP1 EP400 WDR33 APC E2F2 CUL7 MDM4 CIC RESF1 USO1 SEC16A HELZ TANC1 PRRC2B

8.94e-085881811638580884
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

EXOSC10 HIVEP1 EP400 WDR33 ETV3 BCL6 MIDEAS CIC PHF21A KMT2D PRRC2B

1.83e-072681811133640491
Pubmed

BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.

TPR RANBP2 PDLIM7 AAK1 SHTN1 MYOF USO1 ANKRD17 TANC1 JPT2

2.22e-072161811031519766
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TPR MBTD1 EXOSC10 FN1 MAP6 MARS1 ERO1A MBNL1 UTP14A OBSCN APC TFIP11 CAMTA2 RBM28 ANKLE2 RESF1 RLIM SEC16A ANKRD17 TIMELESS ASXL2

2.59e-0710841812111544199
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

RANBP2 ACOT8 CAD EP400 PDLIM7 MARS1 PIEZO1 UTP14A AAK1 APC TFIP11 FAM110A ARHGEF11 CIC SDAD1 MYOF EXD2 CIZ1 CCAR1 ANKRD17 HELZ TANC1 EIF3B SUZ12 ATP1B1

2.84e-0714971812531527615
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ERICH1 EP400 VEZT WDR33 ERO1A APC TFIP11 RBM28 USP8 SPINT2 STXBP3 USO1 TBC1D22A SEC16A HELZ DCLRE1A TANC1

3.34e-077331811734672954
Pubmed

Interaction network of human early embryonic transcription factors.

MBTD1 RANBP2 ZEB1 HIVEP1 EP400 MIDEAS PHF21A KMT2D RESF1 SEC16A ASXL2 PRRC2B

3.58e-073511811238297188
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TPR RANBP2 EXOSC10 CAD FN1 POLE UTP14A USP24 RBM28 CUL7 SEC16A CCAR1 ANKRD17 HELZ PRRC2B SYMPK

3.65e-076531811622586326
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

STK36 EP400 VWA8 CUL7 ARHGEF11 SHTN1 RESF1 BICRAL

4.36e-07130181812421765
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

ERICH1 TDRD15 EXOSC10 FN1 EP400 UTP14A MCAM APC ARFIP2 USO1 EXD2 SEC16A DCLRE1A DEPDC7 SMCR8 PRRC2B AP3S2

7.45e-077771811735844135
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TPR CACNA2D1 RANBP2 CAD ZEB1 MAP6 AAK1 APC ARHGEF11 SHTN1 PICALM CELSR2 PTPRS SEC16A CCAR1 PPP1R3F ANKRD17 UBASH3B PRRC2B

7.63e-079631811928671696
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

TPR RANBP2 PDLIM7 MCAM APC SHTN1 MYOF SEC16A ANKRD17 TANC1

1.05e-062561811033397691
Pubmed

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.

PECR POLE VPS33A USP24 USP8 USP32 TIMELESS MINDY4

1.11e-06147181829576527
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

RANBP2 PDLIM7 APC ANKLE2 PICALM TAB3 SEC16A HELZ TANC1 PRRC2B

1.34e-062631811034702444
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

TPR CACNA2D1 RANBP2 EXOSC10 CAD EP400 PDLIM7 MARS1 UTP14A RBM28 CUL7 HNRNPL SPINT2 EXD2 SEC16A CIZ1 EIF3B ATP1B1 LYN

1.88e-0610241811924711643
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ATRN PCLO MBNL1 CIC BICRAL TANC1

6.51e-0687181612465718
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

TPR FILIP1 RANBP2 UTP14A APC HNRNPL CCAR1 HELZ EIF3B

7.12e-06250181933536335
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

EXOSC10 WDR33 UTP14A TFIP11 SDAD1 HNRNPL ANKRD17 EGFLAM PRRC2B

7.35e-06251181928077445
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

TPR RANBP2 EXOSC10 CAD FN1 EP400 PDLIM7 MARS1 POLE UTP14A AAK1 TFIP11 RBM28 MIDEAS CXXC1 HNRNPL SEC16A CCAR1 ANKRD17 TANC1 EIF3B

8.47e-0613531812129467282
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

PDLIM7 AAK1 FAM110A PLEKHA6 SCEL ARFIP2 SHTN1 PICALM USP8 USO1 TANC1 JPT2 NOTCH3

9.24e-065651811325468996
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

TPR RANBP2 VEZT PDLIM7 MCAM TRAPPC8 ARFIP2 SHTN1 ANKLE2 EXD2 SEC16A TANC1 JPT2

9.77e-065681811337774976
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

UNC13B PECR EXOSC10 ACOT8 FN1 EP400 VWA8 WDR33 AAK1 TFIP11 RBM28 MIDEAS SDAD1 C3P1 TOX4 USO1 SEC16A CCAR1 ANKRD17 ATP1B1 PRRC2B

1.03e-0513711812136244648
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ATMIN ATRN CDS1 VEZT MARS1 MBNL1 OBSCN AAK1 MDM4 SHTN1 HNRNPL HIPK3 USF3 PTPRS TBC1D22A CCAR1 ACSF3 ANKRD17 TANC1 CTDSPL CDH15 NOTCH3

1.10e-0514891812228611215
Pubmed

Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging.

ZEB1 USP24 USP32

1.14e-059181337149635
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

TPR WDR33 HNRNPL TOX4 ANKRD17 HELZ PRRC2B SYMPK

1.21e-05203181822083510
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

TPR RANBP2 EXOSC10 WDR33 PDLIM7 POLE VPS33A USP24 PICALM TOX4 USO1 DEPDC7 SYMPK

1.26e-055821811320467437
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

MCAM PLEKHA6 ERICH5 CBLB ANKLE2 PICALM USP8 STXBP3 CELSR2 SEC16A CTDSPL

1.43e-054211811136976175
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

MBTD1 RANBP2 EXOSC10 EP400 WDR33 TFIP11 RBM28 MIDEAS CXXC1 CIC PHF21A HNRNPL KMT2D TOX4 CIZ1 CCAR1 DCLRE1A ASXL2 SUZ12 SYMPK

1.50e-0512941812030804502
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

WDR33 MIDEAS CIC TAB3 RESF1 CIZ1 PRRC2B

1.58e-05152181738360978
Pubmed

Functional analysis of secreted and transmembrane proteins critical to mouse development.

ATRN FN1 SPINT2 NOTCH3

2.00e-0531181411431694
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

RANBP2 EXOSC10 CAD HIVEP1 EP400 MARS1 MBNL1 RBM28 MIDEAS CIC PHF21A HNRNPL KMT2D RESF1 CCAR1 BICRAL ASXL2 PRRC2B

2.01e-0511031811834189442
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

EXOSC10 CAD WDR33 PDLIM7 MARS1 USP24 RBM28 MIDEAS SDAD1 HNRNPL ANKRD17 EIF3B PRRC2B

2.25e-056151811331048545
Pubmed

The functional interactome landscape of the human histone deacetylase family.

TPR CAD WDR33 UTP14A TFIP11 RBM28 MIDEAS PHF21A SEC16A

2.25e-05289181923752268
Pubmed

Identification of novel interactions between domains of Myosin binding protein-C that are modulated by hypertrophic cardiomyopathy missense mutations.

MYBPC2 MYBPC3

2.69e-052181212386147
Pubmed

Obscurin interacts with a novel isoform of MyBP-C slow at the periphery of the sarcomeric M-band and regulates thick filament assembly.

OBSCN MYBPC3

2.69e-052181219403693
Pubmed

Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.

CBLB PTK2B

2.69e-052181225099615
Pubmed

Loss of circadian gene Timeless induces EMT and tumor progression in colorectal cancer via Zeb1-dependent mechanism.

ZEB1 TIMELESS

2.69e-052181235034102
Pubmed

Support for a trimeric collar of myosin binding protein C in cardiac and fast skeletal muscle, but not in slow skeletal muscle.

MYBPC2 MYBPC3

2.69e-052181218201573
Pubmed

Understanding the organisation and role of myosin binding protein C in normal striated muscle by comparison with MyBP-C knockout cardiac muscle.

MYBPC2 MYBPC3

2.69e-052181218817784
Pubmed

Myocardin regulates fibronectin expression and secretion from human pleural mesothelial cells.

FN1 MYOCD

2.69e-052181238349126
Pubmed

Mammalian hemicentin 1 is assembled into tracks in the extracellular matrix of multiple tissues.

HMCN2 HMCN1

2.69e-052181232035013
Pubmed

Differential methylation of CpG sites in two isoforms of myosin binding protein C, an important hypertrophic cardiomyopathy gene.

MYBPC2 MYBPC3

2.69e-052181220740642
Pubmed

Intact calcium signaling in adrenergic-deficient embryonic mouse hearts.

CACNA2D1 DBH

2.69e-052181229288665
Pubmed

Coagulation induced by C3aR-dependent NETosis drives protumorigenic neutrophils during small intestinal tumorigenesis.

APC C3AR1

2.69e-052181226996437
Pubmed

ZEB1 and CtBP form a repressive complex at a distal promoter element of the BCL6 locus.

ZEB1 BCL6

2.69e-052181220175752
Pubmed

Monocyte chemoattractant protein 1 causes differential signalling mediated by proline-rich tyrosine kinase 2 in THP-1 cells.

PTK2B LYN

2.69e-052181211311138
Pubmed

A 7q21.11 microdeletion presenting with apparent intellectual disability without epilepsy.

CACNA2D1 PCLO

2.69e-052181228240412
Pubmed

Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver.

APC C3AR1

2.69e-052181233798472
Pubmed

The mapping of the Lyn kinase binding site of the common beta subunit of IL-3/granulocyte-macrophage colony-stimulating factor/IL-5 receptor.

CSF2RB LYN

2.69e-05218129973406
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

RANBP2 PDLIM7 MBNL1 UTP14A AAK1 APC MYOF CCAR1 ANKRD17 HELZ DCLRE1A JPT2 PRRC2B AP3S2

2.88e-057241811436232890
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DNHD1 TPR EXOSC10 CAD HNRNPL KMT2D FAM186A CCAR1

3.35e-05234181836243803
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

ACOT8 FN1 PCLO MBNL1 HNRNPL EXD2 NYNRIN RLIM ANKRD17 HELZ PRRC2B

3.36e-054621811131138677
Pubmed

The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.

EP400 APC KMT2D

3.82e-0513181316510874
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

RANBP2 PDLIM7 AAK1 APC ARFIP2 ARHGEF11 ANKLE2 TAB3 STXBP3 TANC1 MINDY4 LYN SUFU JPT2 PRRC2B

4.41e-058531811528718761
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

WDR33 MBNL1 ETV3 ARHGEF11 SEC16A CCAR1 NOTCH3

4.66e-05180181735198878
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

TPR EXOSC10 CAD EP400 PCLO ZNF524 DNAAF2 RESF1 CCAR1 SUZ12

4.71e-053961811026687479
Pubmed

Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions.

CACNA2D1 PDLIM7 MBNL1

4.84e-0514181328826478
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

HIVEP1 AAK1 APC MDM4 SHTN1 CIC TAB3 PTK2B USP8 RESF1 USO1 SEC16A ANKRD17 HELZ TANC1

4.90e-058611811536931259
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UNC13B ATMIN EP400 CAMTA2 TRIL USP8 SEC16A ASXL2 SUZ12 PRRC2B

5.91e-054071811012693553
Pubmed

Regulation of the Mdm2-p53 pathway by the ubiquitin E3 ligase MARCH7.

RANBP2 MDM4 SUZ12

6.02e-0515181329295817
Pubmed

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.

EP400 APC KMT2D

6.02e-0515181316510875
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

EP400 UTP14A TFIP11 CXXC1 PICALM SDAD1 KMT2D TOX4 EIF3B SUZ12

6.28e-054101811026949251
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

CELF5 FN1 MARS1 OBSCN CCDC187 TFIP11 ARHGEF11 SDAD1 HP USP32 CCAR1

6.46e-054971811136774506
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

TPR RANBP2 CAD USP24 AAK1 APC PLEKHA6 ANKLE2 SEC16A TIMELESS JPT2

7.19e-055031811116964243
Pubmed

Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere.

HMCN2 HMCN1

8.05e-053181212388743
Pubmed

A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.

ZEB1 NOTCH3

8.05e-053181221890822
Pubmed

The MBNL1/circNTRK2/PAX5 pathway regulates aerobic glycolysis in glioblastoma cells by encoding a novel protein NTRK2-243aa.

MBNL1 PAX5

8.05e-053181236064939
Pubmed

Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosis.

GAB4 LYN

8.05e-053181212821647
Pubmed

Bcl6 controls granzyme B expression in effector CD8+ T cells.

BCL6 GZMB

8.05e-053181217125145
Pubmed

Association of increased eomesodermin, BCL6, and granzyme B expression with major clinical manifestations of Hashimoto's thyroiditis - an observational study.

BCL6 GZMB

8.05e-053181229319368
Pubmed

Regulation of collagen type I in vascular smooth muscle cells by competition between Nkx2.5 and deltaEF1/ZEB1.

ZEB1 NKX2-5

8.05e-053181215226419
Pubmed

Regulation of cardiac growth and development by SRF and its cofactors.

NKX2-5 MYOCD

8.05e-053181212858529
Pubmed

Quantitative proteomics identifies myoferlin as a novel regulator of A Disintegrin and Metalloproteinase 12 in HeLa cells.

ADAM12 MYOF

8.05e-053181227432471
Pubmed

A Discrete Subset of Monocyte-Derived Cells among Typical Conventional Type 2 Dendritic Cells Can Efficiently Cross-Present.

APC CSF2RB

8.05e-053181229091760
Pubmed

MBNL142 and MBNL143 gene isoforms, overexpressed in DM1-patient muscle, encode for nuclear proteins interacting with Src family kinases.

MBNL1 LYN

8.05e-053181223949219
Pubmed

SRC-dependent outside-in signalling is a key step in the process of autoregulation of beta2 integrins in polymorphonuclear cells.

PTK2B LYN

8.05e-053181214969582
Pubmed

Myocardin expression is regulated by Nkx2.5, and its function is required for cardiomyogenesis.

NKX2-5 MYOCD

8.05e-053181214645532
Pubmed

A secreted protein promotes cleavage furrow maturation during cytokinesis.

HMCN2 HMCN1

8.05e-053181221215633
Pubmed

The transcriptional coactivator CAMTA2 stimulates cardiac growth by opposing class II histone deacetylases.

CAMTA2 NKX2-5

8.05e-053181216678093
Pubmed

Complement component C3a plays a critical role in endothelial activation and leukocyte recruitment into the brain.

C3AR1 C6

8.05e-053181226822321
Pubmed

Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells.

CBLB LYN

8.05e-053181231282857
Pubmed

Thyroid Carcinomas That Occur in Familial Adenomatous Polyposis Patients Recurrently Harbor Somatic Variants in APC, BRAF, and KTM2D.

APC KMT2D

8.05e-053181232024448
Pubmed

β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness.

ZEB1 APC

8.05e-053181222080605
Pubmed

Differential Regulation of NOTCH2 and NOTCH3 Contribute to Their Unique Functions in Vascular Smooth Muscle Cells.

MYOCD NOTCH3

8.05e-053181225957400
Pubmed

Zinc finger protein 277 is an intestinal transit-amplifying cell marker and colon cancer oncogene.

ZEB1 APC

8.05e-053181235015732
Pubmed

Hemicentins assemble on diverse epithelia in the mouse.

HMCN2 HMCN1

8.05e-053181217015624
InteractionBICD2 interactions

TPR RANBP2 PDLIM7 VPS33A MBNL1 UTP14A AAK1 CCDC187 TFIP11 FAM110A ARFIP2 PHF21A TAB3 TANC1 SUFU JPT2

1.38e-0642617916int:BICD2
InteractionMARCHF1 interactions

HNRNPL VPS9D1 USP8 STXBP3 PTPRS EXD2 NOTCH3

2.90e-06701797int:MARCHF1
InteractionSP7 interactions

CAD HIVEP1 EP400 WDR33 MBNL1 TFIP11 RBM28 CBLB MIDEAS CIC KMT2D CCAR1 PRRC2B

3.45e-0630417913int:SP7
InteractionRCOR1 interactions

TPR RANBP2 HIVEP1 VPS33A USP24 APC ZNF524 SHTN1 CIC PHF21A KMT2D TOX4 RESF1 SEC16A ANKRD17 SUZ12

9.07e-0649417916int:RCOR1
InteractionNSUN5P1 interactions

EP400 VPS33A ETV3 CUL7 HNRNPL HELZ

1.38e-05591796int:NSUN5P1
InteractionFEV interactions

ZEB1 HIVEP1 EP400 MIDEAS CXXC1 CIC PHF21A KMT2D ASXL2 PRRC2B

1.42e-0520317910int:FEV
InteractionFBXO42 interactions

CAD HIVEP1 EP400 WDR33 APC HNRNPL USO1 SEC16A HELZ TANC1 PRRC2B

2.11e-0525917911int:FBXO42
InteractionEGR2 interactions

HIVEP1 EP400 MIDEAS PHF21A KMT2D RESF1 SEC16A JPT2 PRRC2B

2.28e-051711799int:EGR2
InteractionAR interactions

TPR DPH1 EXOSC10 HIVEP1 FN1 EP400 WDR33 ETV3 BCL6 MIDEAS CIC PHF21A HNRNPL HIPK3 KDM4D KMT2D AP5B1 SEC16A CCAR1 SUZ12 LYN PRRC2B SYMPK

2.46e-0599217923int:AR
InteractionSMC5 interactions

TPR RANBP2 EXOSC10 HIVEP1 EP400 WDR33 MBNL1 UTP14A TFIP11 RBM28 MIDEAS PICALM CIC HNRNPL TOX4 SEC16A CIZ1 CCAR1 NKX2-5 TIMELESS SPATA22 SUZ12 SYMPK

2.78e-05100017923int:SMC5
InteractionRNF43 interactions

RANBP2 PDLIM7 OBSCN APC ANKLE2 PICALM TAB3 HNRNPL EXD2 CHD5 SEC16A HELZ TANC1 PRRC2B

2.94e-0542717914int:RNF43
InteractionFOXP3 interactions

RANBP2 CAD WDR33 MBNL1 UTP14A AAK1 ETV3 TFIP11 RBM28 MIDEAS HNRNPL USO1 HELZ SUZ12

3.33e-0543217914int:FOXP3
InteractionKLF8 interactions

MBTD1 ZEB1 HIVEP1 EP400 RBM28 CIC PHF21A HNRNPL KMT2D SEC16A EIF3B PRRC2B

3.99e-0532917912int:KLF8
InteractionZYX interactions

FN1 PDLIM7 AAK1 APC PHF21A HIPK3 ARHGAP31 SEC16A CCAR1 HELZ TANC1 SMCR8

3.99e-0532917912int:ZYX
InteractionEN1 interactions

ZEB1 HIVEP1 EP400 MIDEAS CIC KMT2D ASXL2

5.72e-051101797int:EN1
InteractionPHF21A interactions

TPR RANBP2 HIVEP1 USP24 APC CIC PHF21A KMT2D TOX4 RESF1 USO1 SEC16A

5.96e-0534317912int:PHF21A
InteractionPLEKHG7 interactions

POLE VPS33A ETV3 CUL7 AP5B1 RLIM HELZ SYMPK

5.96e-051501798int:PLEKHG7
InteractionPPARD interactions

POLE APC ETV3 CUL7 BCL6 MDM4 SYMPK

8.46e-051171797int:PPARD
InteractionARHGEF9 interactions

TFIP11 BCL6 HNRNPL JPT2

9.00e-05271794int:ARHGEF9
InteractionGOLGA2 interactions

HIVEP1 MBNL1 APC CCDC187 TFIP11 FAM110A RBM28 SCEL BCL6 ZNF524 ARFIP2 CIC KMT2D C12orf50 USO1 SEC16A CCAR1 SPATA22

9.72e-0573317918int:GOLGA2
InteractionDDX17 interactions

RANBP2 ZEB1 FN1 MBNL1 EMC9 CCDC187 TFIP11 RBM28 CUL7 CIC SDAD1 HNRNPL ASXL2

1.17e-0442617913int:DDX17
InteractionH4C4 interactions

FN1 CUL7 CIC RLIM

1.20e-04291794int:H4C4
InteractionHDAC1 interactions

TPR RANBP2 CAD ZEB1 HIVEP1 FN1 EP400 USP24 APC BCL6 SHTN1 MIDEAS CIC PHF21A KMT2D TOX4 USO1 CHD5 ANKRD17 NKX2-5 SUZ12 UBASH3B SYMPK

1.32e-04110817923int:HDAC1
GeneFamilyFibronectin type III domain containing

FN1 OBSCN CSF2RB PTPRS EGFLAM LRRN4 MYBPC2 MYBPC3

4.25e-061601058555
GeneFamilyUbiquitin specific peptidases

USP49 USP24 USP8 USP32

3.13e-04561054366
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

OBSCN HMCN2 HMCN1 PTPRS MYBPC2 MYBPC3

3.54e-041611056593
GeneFamilyFibronectin type III domain containing|I-set domain containing|Myosin binding proteins

MYBPC2 MYBPC3

9.14e-0481052658
GeneFamilyFibulins

HMCN2 HMCN1

9.14e-0481052556
GeneFamilyPHD finger proteins

CXXC1 PHF21A KMT2D CHD5

1.87e-0390105488
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

DPH1 PTK2B RESF1

3.24e-03511053870
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MBNL1 BCL6 SDAD1 PHF21A VPS9D1 TOX4 CSF2RB HP FAM186A

3.43e-081711809dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MBNL1 BCL6 SDAD1 PHF21A VPS9D1 TOX4 CSF2RB HP FAM186A

3.43e-0817118092b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FILIP1 ZEB1 FN1 PDLIM7 AAK1 MYOF MYOCD ATP1B1

6.71e-0717818080fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

FN1 PDLIM7 MCAM MYOF SPINT2 HMCN2 MYOCD NOTCH3

8.27e-071831808818fd886e0188091310825f9145fa53328f2c979
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

FN1 PDLIM7 MCAM MYOF SPINT2 HMCN2 MYOCD NOTCH3

8.27e-071831808cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

FN1 PDLIM7 MBNL1 MCAM MYOF HMCN2 MYOCD NOTCH3

1.05e-0618918086b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

ATRN RANBP2 USP8 USF3 USP32 ASXL2 SUZ12 SMCR8

1.23e-061931808abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

B3GNT7 SCEL SHTN1 CSF2RB CD300LG C3AR1 DEPDC7

3.16e-061541807c663e9834be0b45389a862dc3c13a1f988a3e5ee
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGEL2 OBSCN HP NKX2-5 ATP1B1 MYBPC2 MYBPC3

3.59e-0615718079021900d9b1a71210c9c414a9d165eaf399eb607
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGEL2 OBSCN HP NKX2-5 ATP1B1 MYBPC2 MYBPC3

3.59e-061571807c8c627ca181856cd31dba4cf073c2be659a49dc1
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

FN1 PDLIM7 MCAM SPINT2 HMCN2 EGFLAM NOTCH3

4.24e-06161180747b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACOT8 B3GNT7 SCEL SHTN1 CD300LG TIMELESS DEPDC7

5.61e-061681807cc0dd43d5cda01e643d8e8d74ec7617d61890760
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8|TCGA-Liver / Sample_Type by Project: Shred V9

TDRD15 VWA8 C3P1 HMCN2 PLCH2 CD300LG C6

6.30e-061711807c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MCAM ADAM12 MYOF EGFLAM SUFU CTDSPL NOTCH3

1.02e-051841807327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA2D1 ZEB1 FN1 PDLIM7 MYOCD SLITRK6 UBASH3B

1.13e-051871807c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF5 PCLO PTK2B CELSR2 PLCH2 CHD5 ATP1B1

1.13e-051871807e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF5 PCLO PTK2B CELSR2 PLCH2 CHD5 ATP1B1

1.13e-05187180724cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF5 PCLO PTK2B CELSR2 PLCH2 CHD5 ATP1B1

1.13e-0518718072f153b203fe79f206319603cf94d3a03ab49a05d
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

FN1 PDLIM7 MBNL1 MYOF HMCN2 MYOCD NOTCH3

1.17e-05188180734e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FN1 PLEKHA6 CBLB TRIL HMCN1 PTPRS SLITRK6

1.25e-0519018071196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 ZEB1 FN1 PDLIM7 ADAM12 MYOCD NOTCH3

1.25e-05190180770c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 CACNA2D1 MCAM TRIL MYOCD EGFLAM NOTCH3

1.29e-0519118078597a8af294f24496c317d995f07eb5dcc25c13c
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 FN1 BCL6 MYOF PTPRS LRRN4 ATP1B1

1.34e-0519218070dc1f46e40346ed0b286e53b106a812441575100
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF5 CACNA2D1 PCLO PTK2B CELSR2 CHD5 SCN8A

1.38e-0519318078689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FILIP1 FN1 PDLIM7 MYOF HMCN2 MYOCD ATP1B1

1.38e-0519318070256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF5 CACNA2D1 PCLO PTK2B CELSR2 CHD5 SCN8A

1.38e-051931807be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF5 CACNA2D1 PCLO PTK2B CELSR2 CHD5 SCN8A

1.38e-0519318070c652ebe22ce5d2927599dd97ef1920547858395
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZEB1 FN1 PDLIM7 MCAM HMCN1 MYOCD NOTCH3

1.38e-0519318075de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 CACNA2D1 MCAM TRIL MYOCD EGFLAM NOTCH3

1.43e-05194180780be44e9ddd9f6ddd9dff7cba0eb457431204c2d
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

CELF5 MAP6 PCLO SHTN1 SPINT2 CHD5 ATP1B1

1.69e-0519918075de2a32bc2e9c752eb19a013b1807949153728fc
ToppCellSigmoid-T_cell-gd_T|T_cell / Region, Cell class and subclass

ABI3 PDLIM7 B3GNT7 CBLB GZMB UBASH3B LYN

1.74e-05200180720844293c155d3f319ceeea9476979bc86515b53
ToppCellfacs-Marrow-B-cells-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DBH ADAM12 CSF2RB PTPRS EGFLAM ATP1B1

2.56e-0514318066df16bf0324661cd9707df69cb39f4b5498d6d49
ToppCellPericytes-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

ZEB1 MCAM TRIL MYOCD TANC1 NOTCH3

3.35e-051501806dbc202bd6db4fb5c8b2abd1200e074a2a9e63a59
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

PCLO CCDC187 C11orf16 ERICH5 C6 SLITRK6

4.17e-05156180610d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

FN1 PDLIM7 HMCN1 PTPRS NYNRIN SLC4A9

4.64e-0515918063f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellP15-Epithelial-epithelial_progenitor_cell-epi_progenitor|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYOF SPINT2 SLCO4C1 DMKN C6 ATP1B1

4.64e-051591806a4bfd59c53237964fc24a24de5c1925fdd01db99
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

FN1 PDLIM7 MCAM SPINT2 EGFLAM NOTCH3

4.80e-05160180629c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBTD1 CDS1 OBSCN CSF2RB PTPRS NOTCH3

4.80e-051601806237430af14830b38e58da8a4224036e5c6b71c5b
ToppCellMild-MAIT|Mild / Disease group and Cell class

MCAM TDRD1 ADAM12 NYNRIN TANC1 LYN

4.97e-0516118060c1a04485708d5302600cdc2d7dac1cb76b4033a
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1A PLEKHA6 CIC USF3 SPINT2 CELSR2

4.97e-0516118063f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCelldroplet-Kidney-nan-24m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABI3 FN1 CSF2RB HP C6 LYN

5.51e-051641806d57faa4fce1f1e9a92aaf5cb920af99323252e4b
ToppCelldroplet-Kidney-nan-24m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABI3 FN1 CSF2RB HP C6 LYN

5.51e-051641806d0b6c29e61d15f4dbe4c1f6e5ed3e10f41f820ab
ToppCelldroplet-Kidney-nan-24m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABI3 FN1 CSF2RB HP C6 LYN

5.51e-051641806718cc64b7ef7d03d095be4b2b54c449154da568c
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

E2F2 SHTN1 RESF1 CSF2RB HP DMKN

6.09e-0516718061bd27ffe381d26731b6d4cc5f29b27f1bac4473b
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

CACNA2D1 PDLIM7 MCAM TRIL HMCN2 NOTCH3

6.09e-051671806c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B PIEZO1 SPINT2 HMCN1 ARHGAP31 SLC4A9

6.30e-05168180606dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B PIEZO1 SPINT2 HMCN1 ARHGAP31 SLC4A9

6.30e-0516818061002f058a340763e3d8de0bd1f0547a903526ec6
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|Myeloid_cells / Location, Cell class and cell subclass

UNC13B DNHD1 EXOSC10 ETV3 STXBP3 HP

6.51e-051691806dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCelldroplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDS1 OBSCN CSF2RB PTPRS ATP1B1 NOTCH3

6.51e-0516918067962165cab84af73d20b56eb70b1ed87c94025ef
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FN1 E2F2 CSF2RB DMKN AP5B1 CTDSPL

6.51e-051691806813472d429c0b12580b17b440e00a6d8beb7947f
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDS1 SPINT2 SLCO4C1 DMKN C6 ATP1B1

6.51e-05169180653e863de064d44e1d36e21fb3dbba37ae020f6e9
ToppCellP03-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPINT2 SLCO4C1 HP DMKN C6 ATP1B1

6.72e-0517018063fd37e9b377d6485cea1262c31a8507d18a78514
ToppCellfacs-Trachea-nan-18m-Myeloid-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV3 SHTN1 PTK2B CSF2RB C3AR1 LYN

6.72e-051701806774b0c1b453e19651f9481dc6bcabac538c5acb7
ToppCellP15-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPINT2 SLCO4C1 HP DMKN C6 ATP1B1

6.72e-0517018066c0619cbe2f01a6de18da0a137f92bda0cbdf075
ToppCellfacs-Trachea-nan-18m-Myeloid|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV3 SHTN1 PTK2B CSF2RB C3AR1 LYN

6.94e-0517118069d496a6edac9663791cda684188d49895246f6fe
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECR VWA8 COL6A5 ARHGEF11 ADAM12 C3AR1

6.94e-051711806a474aaed3ca4cacb0ab565c35f25d92a10f531b7
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FILIP1 ZEB1 FN1 PDLIM7 MYOCD ATP1B1

6.94e-051711806fe0665c5ca01b0b2cc8f20d64587f0847c3d215c
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

CACNA2D1 PDLIM7 MCAM TRIL MYOCD NOTCH3

7.17e-051721806c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellLeuk-UTI-Myeloid-cDC1|Leuk-UTI / Disease, Lineage and Cell Type

CDS1 B3GNT7 PLEKHA6 SHTN1 ERICH5 STPG4

7.41e-051731806226bb8d881f32d65c60f5e4c034c6d465f8e7ba5
ToppCelldroplet-Thymus-nan-24m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 SHTN1 MYOF CSF2RB HP C3AR1

7.64e-05174180644c21521991ad4789783d73d5aa4993a22876886
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

RANBP2 ETV3 ZNF251 USF3 USP32 HELZ

7.64e-0517418062274648b80dd74f3c948a779bba3391095964c34
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ZEB1 EMC9 ZNF524 USP32 C3AR1 SUZ12

7.89e-051751806da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GALNAC1 PIEZO1 ANKRD30B B3GNT7 SCEL SCN8A

7.89e-051751806019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABI3 PTK2B CSF2RB C3AR1 UBASH3B LYN

8.14e-0517618064f37854124d77ee64dcb40fd491eaed2ba389891
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABI3 PTK2B CSF2RB C3AR1 UBASH3B LYN

8.14e-051761806d687e6c3f9043f2574d072f815b8c2258f9dc7b5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABI3 PTK2B CSF2RB C3AR1 UBASH3B LYN

8.14e-0517618060afba8707b847e5bdf6f38fe4379967631fe2240
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STK36 C11orf16 DMKN SLITRK6 DNAH6 CCDC33

8.40e-05177180612a52a12a87a31e501ced611f46a90d172ca7e35
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPH1 HMCN1 DMKN NYNRIN PLCH2 CTDSPL

8.40e-05177180675cb2067a3f2d1b5a964890b02b604d1e79bd163
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STK36 C11orf16 DMKN SLITRK6 DNAH6 CCDC33

8.40e-0517718063cfde67b93f3986312f5e74e42504214d966e7dc
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA2D1 ZEB1 OBSCN MCAM CTDSPL NOTCH3

8.66e-051781806185b44700f06ec58b3c09c80520502166c965fd6
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 CSF2RB HP DMKN CD300LG CTDSPL

8.66e-051781806be8af4d85b8835a85a168639c37857dcaa6b00bf
ToppCellfacs-Trachea-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 C11orf16 C12orf50 SLITRK6 DNAH6 CCDC33

9.21e-051801806cf6e9f757afeb342c5023f6e6152a1b4d0d164b4
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

CACNA2D1 FN1 PDLIM7 MCAM MYOCD NOTCH3

9.21e-051801806d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

CELF5 ZEB1 FN1 MCAM MYOCD EGFLAM

9.21e-0518018067085a851807e6a833965e1366946db0bbc5174e2
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA2D1 ZEB1 MCAM RIPOR3 EGFLAM NOTCH3

9.50e-05181180633cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA2D1 FN1 HMCN1 NRK MYOCD DEPDC7

9.50e-051811806b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellfacs-Marrow-T-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 CSF2RB PTPRS CD300LG C3AR1 ATP1B1

9.50e-0518118067286700396676fdc41d9723979b8b408177aceb9
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CELF5 MAP6 PCLO DBH ERICH5 PTPRS

9.50e-0518118067f99002a6411117cc2361334c7c9228e20c574b4
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HIVEP1 POLE SHTN1 TAB3 ATP1B1 SYMPK

1.01e-041831806807d64deaf4e50dccf6f831f88578a6d903c1421
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 PCLO OBSCN HMCN1 NRK MYOCD

1.04e-0418418062cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 PCLO OBSCN HMCN1 NRK MYOCD

1.04e-0418418062b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

FILIP1 CACNA2D1 OBSCN AAK1 MYOCD MYBPC3

1.04e-041841806ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 PCLO OBSCN HMCN1 NRK MYOCD

1.04e-041841806ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

FILIP1 VWA8 OBSCN AAK1 MYOCD MYBPC3

1.07e-0418518066baccb26f999145e51b91d94315bf8d4655bef31
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FILIP1 MAP6 C11orf16 CC2D2A DNAH6 CCDC33

1.07e-0418518065e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZEB1 HIVEP1 MIDEAS HNRNPL DMKN RLIM

1.07e-041851806eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellMild-Myeloid-Neutrophil|Mild / Condition, Lineage, Cell class and cell subclass

BCL6 CELSR2 C12orf50 DMKN

1.08e-04611804b2c4413cf80537fd4e9914d6285278ad9c27dc76
ToppCellMild-Myeloid-Neutrophil-|Mild / Condition, Lineage, Cell class and cell subclass

BCL6 CELSR2 C12orf50 DMKN

1.08e-046118048793db9dd73c7ea4b8ed9f1acf5193a5a2dd1468
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

UNC13B CELF5 CACNA2D1 ADAM12 PTK2B SPINT2

1.10e-04186180656c139e679d640ea901ead657a8e8887e0fca098
ToppCellfacs-Trachea-nan-24m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 C11orf16 SPINT2 DMKN PLCH2 ATP1B1

1.10e-0418618066c06163d7315f1c71b15fe76f2e696bf3fa73b67
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FILIP1 MAP6 C11orf16 CC2D2A DNAH6 CCDC33

1.10e-04186180676033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellCOVID_vent-Myeloid-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

PLEKHA6 SHTN1 MYOF SPINT2 ARHGAP31 ATP1B1

1.10e-04186180663a5cdd3f60681762a218be32db84be8f29b88fd
ToppCellCOVID_vent-Myeloid-Dendritic-cDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

PLEKHA6 SHTN1 MYOF SPINT2 ARHGAP31 ATP1B1

1.10e-04186180639457a7b43537f2c3e221f9375c95d4515424d7d
ToppCellfacs-Trachea-nan-24m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 C11orf16 SPINT2 DMKN PLCH2 ATP1B1

1.10e-04186180678e3b00eb347d1aa197671e31be9b0c6e4235760
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

TPR APC USP8 RESF1 HMCN1 ASXL2

1.10e-04186180603db813598b67b1e08f759758a1c2023396921fa
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

CACNA2D1 FN1 PDLIM7 MCAM MYOCD NOTCH3

1.14e-041871806464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

OBSCN MCAM MYOF EGFLAM TANC1 NOTCH3

1.14e-041871806a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FILIP1 USP24 HMCN1 ARHGAP31 NYNRIN MYOCD

1.17e-0418818066468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FILIP1 USP24 HMCN1 ARHGAP31 NYNRIN MYOCD

1.17e-0418818067a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FILIP1 USP24 HMCN1 ARHGAP31 NYNRIN MYOCD

1.17e-0418818069cb718bfe1358c6fd842f096e228eb0abb9aefc6
DrugPepstatin A [26305-03-3]; Up 200; 5.8uM; MCF7; HT_HG-U133A

FN1 MARS1 UTP14A USP24 CAMTA2 MYOF TOX4 NYNRIN CTDSPL SYMPK MYBPC3

5.03e-07199178113264_UP
DrugScopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A

PECR AAK1 APC ARHGEF11 PICALM PTK2B TOX4 PTPRS CHD5 PAX5

3.62e-06197178104803_UP
DrugNorgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; PC3; HT_HG-U133A

UTP14A AAK1 APC TFIP11 SCEL CUL7 ADAM12 HIPK3 PTPRS TIMELESS

3.62e-06197178103708_DN
DrugNatamycin [7681-93-8]; Up 200; 6uM; MCF7; HT_HG-U133A

MBTD1 VEZT WDR33 UTP14A AAK1 APC C11orf16 MYOF CSF2RB CIZ1

3.78e-06198178103548_UP
DrugTocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A

MARS1 CAMTA2 CUL7 PHF21A MYOF CIZ1 BICRAL TIMELESS SYMPK

2.49e-0519617893256_UP
DrugNorethindrone [68-22-4]; Down 200; 13.4uM; PC3; HT_HG-U133A

VPS33A PLEKHA6 CUL7 ARHGEF11 HIPK3 MYOF SCN8A LYN NOTCH3

2.59e-0519717895055_DN
DrugZimelidine dihydrochloride monohydrate [61129-30-4]; Down 200; 9.8uM; HL60; HG-U133A

UNC13B ATRN RANBP2 FN1 AAK1 MYOF TOX4 CIZ1 PRRC2B

2.59e-0519717892012_DN
Drug16, 16-dimethylprostaglandin E2 methyl acetate solution; Down 200; 10uM; PC3; HT_HG-U133A

DPH1 MBTD1 EP400 PDLIM7 AAK1 PLEKHA6 MYOF CELSR2 CTDSPL

2.70e-0519817896592_DN
DrugRanitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; PC3; HT_HG-U133A

MARS1 PIEZO1 USP24 PLEKHA6 ARHGEF11 ADAM12 TOX4 CTDSPL NOTCH3

2.70e-0519817892088_DN
DrugThyroxine (L) [51-48-9]; Up 200; 5.2uM; MCF7; HT_HG-U133A

CACNA2D1 APC CUL7 MDM4 MYOF TBC1D22A TIMELESS CTDSPL SYMPK

2.80e-0519917893249_UP
Diseasecolorectal cancer (implicated_via_orthology)

POLE APC LYN NOTCH3

3.04e-05301774DOID:9256 (implicated_via_orthology)
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

TDRD15 CELSR2 ANKRD17

7.36e-05141773EFO_0004611, EFO_0008589
DiseaseGlioblastoma

FN1 APC MDM4 SUZ12 NOTCH3

1.16e-04791775C0017636
DiseaseGiant Cell Glioblastoma

FN1 APC MDM4 SUZ12 NOTCH3

1.54e-04841775C0334588
Diseasefree cholesterol measurement, low density lipoprotein cholesterol measurement

TDRD15 USP24 CELSR2 NYNRIN ANKRD17 CD300LG

1.84e-041371776EFO_0004611, EFO_0008591
Diseasecholesteryl esters to total lipids in small VLDL percentage

TDRD15 CELSR2 SEC16A CD300LG

2.15e-04491774EFO_0022256
Diseasepulmonary alveolar proteinosis (implicated_via_orthology)

MARS1 CSF2RB

3.54e-0451772DOID:12120 (implicated_via_orthology)
Diseaseelectrocardiography

HIVEP1 OBSCN B3GNT7 DBH PLEKHA6 USP8 HMCN2 MYOCD ATP1B1 SUFU MYBPC3

3.80e-0453017711EFO_0004327
DiseaseIntellectual Disability

PECR APC RBM28 CIC PHF21A TBC1D20 ZDHHC9 RLIM SCN8A SUZ12

3.91e-0444717710C3714756
Diseasediabetic angiopathy (implicated_via_orthology)

FN1 PTK2B

5.28e-0461772DOID:11713 (implicated_via_orthology)
DiseaseGlioblastoma Multiforme

FN1 APC MDM4 SUZ12 NOTCH3

5.63e-041111775C1621958
DiseaseMalignant neoplasm of breast

CDS1 ZEB1 FN1 PDLIM7 OBSCN TRAPPC8 MDM4 ADAM12 CIC HNRNPL KMT2D HP CHD5 GZMB TIMELESS NOTCH3

7.85e-04107417716C0006142
Diseasecongenital heart disease (implicated_via_orthology)

KMT2D NKX2-5 MYBPC2 MYBPC3

7.98e-04691774DOID:1682 (implicated_via_orthology)
Diseaseesterified cholesterol measurement, intermediate density lipoprotein measurement

TDRD15 CELSR2

9.78e-0481772EFO_0008589, EFO_0008595
DiseaseSudden Cardiac Death

NKX2-5 MYBPC3

9.78e-0481772C0085298
Diseaseovarian cancer (implicated_via_orthology)

POLE APC

9.78e-0481772DOID:2394 (implicated_via_orthology)
Diseaseesterified cholesterol measurement

TDRD15 CELSR2 NYNRIN ANKRD17 CD300LG

1.07e-031281775EFO_0008589
Diseaselung cancer (implicated_via_orthology)

TPR POLE

1.25e-0391772DOID:1324 (implicated_via_orthology)
Diseasenon-high density lipoprotein cholesterol measurement

TDRD15 MBTD1 HIVEP1 FN1 MIDEAS ENAM CELSR2 USO1 HP NYNRIN HELZ UBASH3B

1.30e-0371317712EFO_0005689
Diseasecholesteryl esters to total lipids in very large HDL percentage

TDRD15 CELSR2 CD300LG

1.31e-03361773EFO_0022257
Diseasefree cholesterol to total lipids in large VLDL percentage

TDRD15 CELSR2 SEC16A

1.42e-03371773EFO_0022281
DiseaseAnemia, Sickle Cell

CAD HP

1.56e-03101772C0002895
Diseasemedulloblastoma (is_implicated_in)

APC SUFU

1.56e-03101772DOID:0050902 (is_implicated_in)
Diseaselipoprotein measurement, phospholipid measurement

TDRD15 CELSR2 NYNRIN CD300LG

1.74e-03851774EFO_0004639, EFO_0004732
Diseaselate-onset Alzheimers disease

ABI3 ERO1A PICALM HMCN1 PTPRS USP32 DNAH6

1.99e-032921777EFO_1001870
Diseaseendometrial carcinoma (is_implicated_in)

POLE APC

2.27e-03121772DOID:2871 (is_implicated_in)
DiseaseAbruptio Placentae

TDRD15 ADAM12

2.27e-03121772EFO_1001754
Diseaseapolipoprotein B measurement

TDRD15 CACNA2D1 FN1 USP24 MIDEAS USP8 MYOF STXBP3 CELSR2 NYNRIN SYMPK

2.30e-0366317711EFO_0004615
Diseasewhite matter microstructure measurement

CACNA2D1 BCL6 SHTN1 ASXL2 SUZ12 SUFU CCDC157 SLC4A9

2.55e-033901778EFO_0005674
Diseasemonocyte count

ATRN HIVEP1 FN1 RNLS PIEZO1 ETV3 RIPOR3 B3GNT7 PLEKHA6 BCL6 TDRD1 CIC PTK2B UBASH3B LYN CTDSPL MYBPC3

2.57e-03132017717EFO_0005091
Diseasesexual dimorphism measurement

USP49 FILIP1 MARS1 VPS33A APC BCL6 SPATA31C1 PHF21A AP5B1 NYNRIN SEC16A CD300LG ASXL2 SUFU MYBPC3

2.83e-03110617715EFO_0021796
DiseaseGastrointestinal Stromal Sarcoma

STK36 CC2D2A SUFU

2.83e-03471773C3179349
DiseaseImpaired cognition

PICALM NOTCH3

3.11e-03141772C0338656
Disease5-methyluridine (ribothymidine) measurement

PCLO PTPRS

3.11e-03141772EFO_0020013
Diseaselymphocyte count

HIVEP1 FN1 PCDHGA6 PIEZO1 MBNL1 RIPOR3 E2F2 PLEKHA6 ARHGEF11 ANKLE2 TDRD1 TOX4 ARHGAP31 NKX2-5 HELZ CD300LG UBASH3B CTDSPL

3.16e-03146417718EFO_0004587
Diseasephospholipids in medium LDL measurement

TDRD15 CELSR2 NYNRIN

3.19e-03491773EFO_0022183
Diseasehematocrit

TDRD15 STK36 CACNA2D1 HIVEP1 RNLS PIEZO1 MBNL1 AAK1 PLEKHA6 BCL6 ANKRD17 ASXL2 CTDSPL CCDC157

3.24e-03101117714EFO_0004348
Diseasemultiple sclerosis

RNLS VWA8 ETV3 BCL6 CBLB CSF2RB ACSF3 UBASH3B CDH15 MYBPC3

3.26e-0359417710MONDO_0005301
Diseasemean reticulocyte volume

USP49 CAD EP400 PIEZO1 E2F2 USP8 RESF1 NYNRIN CC2D2A ACSF3 LYN CDH15

3.32e-0379917712EFO_0010701
DiseaseGastrointestinal Stromal Tumors

STK36 CC2D2A SUFU

3.38e-03501773C0238198
DiseaseColorectal Carcinoma

UNC13B ERICH1 CAD FN1 POLE OBSCN APC DMKN PTPRS CHD5 CCAR1

3.55e-0370217711C0009402
Diseaseresponse to statin, LDL cholesterol change measurement

TDRD15 CELSR2

3.57e-03151772EFO_0007804, GO_0036273
Diseaseanemia (implicated_via_orthology)

APC SLC4A9

3.57e-03151772DOID:2355 (implicated_via_orthology)
Diseasecholesterol to total lipids in small VLDL percentage

TDRD15 CELSR2 CD300LG

3.58e-03511773EFO_0022242
DiseaseOrofacial cleft

SHTN1 EGFLAM SUFU

3.58e-03511773HP_0000202
Diseasetotal lipids in LDL measurement

TDRD15 CELSR2 NYNRIN

3.78e-03521773EFO_0022308
Diseasecorpus callosum posterior volume measurement

CACNA2D1 SHTN1 SUFU

3.78e-03521773EFO_0010298
Diseasecholesteryl esters to total lipids in very large VLDL percentage

TDRD15 CELSR2 CD300LG

3.99e-03531773EFO_0022258
DiseaseT-Cell Lymphoma

BCL6 KMT2D

4.06e-03161772C0079772
Diseasehair colour measurement

PIEZO1 MBNL1 SCEL VPS9D1 KMT2D C12orf50 TBC1D22A ACSF3 ASXL2 CDH15

4.15e-0361517710EFO_0007822
Diseasecholesterol to total lipids in very large VLDL percentage

TDRD15 CELSR2 CD300LG

4.21e-03541773EFO_0022244
DiseaseBenign neoplasm of stomach

POLE APC

4.59e-03171772C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

POLE APC

4.59e-03171772C0496905
DiseaseCarcinoma in situ of stomach

POLE APC

4.59e-03171772C0154060
Diseasecholesterol to total lipids in chylomicrons and extremely large VLDL percentage

TDRD15 CELSR2

4.59e-03171772EFO_0022232
Diseasecholesterol to total lipids in large LDL percentage

TDRD15 CELSR2 MYBPC3

4.66e-03561773EFO_0022235
Diseasefree cholesterol to total lipids in large HDL percentage

TDRD15 CELSR2 CD300LG

4.66e-03561773EFO_0022279
Diseasemonocyte percentage of leukocytes

RNLS PIEZO1 E2F2 B3GNT7 BCL6 ARHGEF11 USP8 SEC16A C3AR1 UBASH3B LYN

4.80e-0373117711EFO_0007989
Diseasefree cholesterol to total lipids in medium VLDL percentage

TDRD15 CELSR2 CD300LG

4.90e-03571773EFO_0022284
Diseaseessential hypertension (is_implicated_in)

RNLS ATP1B1

5.14e-03181772DOID:10825 (is_implicated_in)
Diseaselevel of Sphingomyelin (d34:1) in blood serum

USP24 ANKRD17

5.14e-03181772OBA_2045175
Diseasevery low density lipoprotein cholesterol measurement, esterified cholesterol measurement

TDRD15 CELSR2

5.14e-03181772EFO_0008317, EFO_0008589
Diseaselow density lipoprotein particle size measurement

TDRD15 CELSR2 CD300LG

5.14e-03581773EFO_0008593
Diseasetriglycerides to total lipids in small VLDL percentage

TDRD15 CELSR2 CD300LG

5.14e-03581773EFO_0022338
Diseasecholesterol in IDL measurement

TDRD15 CELSR2 CD300LG

5.14e-03581773EFO_0021899
Diseasephospholipids in LDL measurement

TDRD15 CELSR2 NYNRIN

5.14e-03581773EFO_0022294
DiseaseMalignant neoplasm of skin

POLE PTK2B NOTCH3

5.39e-03591773C0007114
Diseasephospholipids in small LDL measurement

TDRD15 CELSR2 NYNRIN

5.39e-03591773EFO_0022297
DiseaseSkin Neoplasms

POLE PTK2B NOTCH3

5.39e-03591773C0037286
Diseasetotal lipids in IDL

TDRD15 CELSR2 CD300LG

5.65e-03601773EFO_0022161
Diseaseglomerulonephritis (is_marker_for)

FN1 PTK2B

5.72e-03191772DOID:2921 (is_marker_for)
Diseasehydrocephalus (implicated_via_orthology)

STK36 CELSR2

5.72e-03191772DOID:10908 (implicated_via_orthology)
Diseasetotal blood protein measurement

CACNA2D1 RNLS MBNL1 KMT2D NYNRIN SEC16A ACSF3 UBASH3B

5.91e-034491778EFO_0004536
Diseasefree cholesterol in IDL measurement

TDRD15 CELSR2 CD300LG

5.92e-03611773EFO_0022181

Protein segments in the cluster

PeptideGeneStartEntry
SPPKEVNIKPGNNVR

TDRD1

121

Q9BXT4
EIKPVNPSPLSQLQR

ACOT8

186

O14734
GKREPQTLAVQNPPK

ERICH1

26

Q86X53
LVQQQQVLQGPPLPR

EP400

276

Q96L91
QCQNPLRQKLPPGAE

SLC4A9

211

Q96Q91
SQDPQRILKPAEGNP

ANKLE2

131

Q86XL3
RVAPPGLTQIPQIQK

ATP1B1

71

P05026
VAPQPIPIQRKGKNG

EGFLAM

321

Q63HQ2
PRPPTLLSQEQIKQI

EIF3B

706

P55884
PQVLGPQQRPRKSDA

CCDC187

136

A0A096LP49
IRKLPKNPQNTNPEG

ANKRD30B

261

Q9BXX2
PNPSKVLQQLLVLQP

CDS1

421

Q92903
QDRSKPPPLNRQQGK

CCDC33

776

Q8N5R6
PGAQKPRQPLEVQAL

CHD5

1581

Q8TDI0
KAGQTQPNPGILPIQ

AAK1

371

Q2M2I8
QPQQKAGLLQPPVRI

CCAR1

271

Q8IX12
PQNKPRPLTQEEIAQ

EFL1

426

Q7Z2Z2
QFSIKLQPPPVGRKN

ETV3

341

P41162
PLRLPSNKAQVKPGQ

GZMB

126

P10144
QRITGPKPLQDPEVQ

ARHGEF11

161

O15085
KNINLPEIPRNINIG

AP3S2

166

P59780
LKQNQELEGLPQPGL

CAMTA2

1186

O94983
GLNVPQPQSTQRVLP

ADAM12

806

O43184
PLPGVQVRIVSENPQ

ACSF3

381

Q4G176
QQFNIKLRPPGAEKP

ARFIP2

321

P53365
RPPPRQSLQEQLNGV

CELSR2

2881

Q9HCU4
LQREQLSPPQVQPGF

DNHD1

3706

Q96M86
QQEAVPKIPQPKRQS

DEPDC7

226

Q96QD5
IKNPVNNVRPGFPVS

ANKRD17

1866

O75179
GRVANQIPPEILKNP

DPH1

31

Q9BZG8
PLENRSLENIVQPPG

C3AR1

191

Q16581
QPLPQKGANQRETPT

CCDC157

136

Q569K6
GKTLQSKQLPQVPRP

ASXL2

1021

Q76L83
QNLNPSNKELVGPPL

RANBP2

1376

P49792
NNNPEIFGPLKRPIV

RBM28

561

Q9NW13
NRIIRTKVQQPPNQP

PAX5

136

Q02548
QRLPPGQKVIAPENL

ABI3

116

Q9P2A4
KGEPRQLQQAPPNTD

PCDHGA6

801

Q9Y5G7
DQGPTVLQPPKNQGR

MAP6

726

Q96JE9
VLQPPKNQGRIVPEP

MAP6

731

Q96JE9
PAQEAQRQAPPLVQL

MAGEL2

631

Q9UJ55
QRQAPPLVQLEQPFQ

MAGEL2

636

Q9UJ55
KPKNPANPVQRILGG

HP

151

P00738
APLPSNLPIIKNNGQ

MBTD1

26

Q05BQ5
PGQINQVRPKLPLLK

MDM4

21

O15151
PRIQPQSLQGDLNPL

DNAAF2

541

Q9NVR5
QKTGPGILQQRQKPP

FOXL2NB

71

Q6ZUU3
GILQQRQKPPAPRAS

FOXL2NB

76

Q6ZUU3
QVPPQVQPGPRVLKV

HMCN2

1161

Q8NDA2
SGAVRNRKQQPPAQP

ATRN

1411

O75882
NIFGPTEEPQNIPKR

JPT2

46

Q9H910
LAQRRKPQPDPLQIP

CBLB

486

Q13191
QQPQQKVLGSRELPP

EXD2

41

Q9NVH0
AAVQQLRIQPTKPPN

PCLO

4921

Q9Y6V0
LPPTKQARVIPIQCN

PECR

66

Q9BY49
KVKPLLLQLQRQPQP

CUL7

651

Q14999
NTRQEPVQPLLSKQP

FAM110A

61

Q9BQ89
QLGPQPEVTPKRQVL

NOTCH3

2306

Q9UM47
LPQVRPKPVAQNNIP

PHF21A

231

Q96BD5
PPQKLRAQELTLQTP

KDM4D

456

Q6B0I6
NLRQQPQPQELGVIP

GOLGA2P5

66

Q9HBQ8
NGNIESVPKQIPPRP

LRRC63

261

Q05C16
QGQPPALFKPQLVRL

AP5B1

301

Q2VPB7
TIPAALQQVKNPVPR

POLE

1146

Q07864
IVQPNPSVLIGNPIR

HELZ

1146

P42694
TQAPAVQPLQIRPGV

HIPK3

656

Q9H422
QRQDQTLELVGLPPP

NKX2-5

196

P52952
QNGQPLRPLVPDASK

PDLIM7

131

Q9NR12
EQLANQGIIPPLKRP

MYOCD

31

Q8IZQ8
ILTVNVPPNIKGGPQ

HMCN1

3706

Q96RW7
PLSDPIQVKTQQGVP

PTPRS

511

Q13332
QQQQEPLAAVRPPLG

OBSCN

4846

Q5VST9
GQQPLQKIPPLQGVS

ERVK-5

636

Q9HDB9
KNQQPVLPAGLQVPK

EXOSC10

136

Q01780
NKTIESLNNQPIPRP

ATMIN

241

O43313
RRPLPTQQQPQPSQK

CXXC1

236

Q9P0U4
TQLEKGLPPNSVVPQ

DNAH6

931

Q9C0G6
PGQAVPQVPVIQLFK

CSF2RB

861

P32927
GLAPNSNKVPINIQP

BICRAL

301

Q6AI39
ENGIPLIPPLSQQNI

CC2D2A

811

Q9P2K1
PTRPGKQQQLGQELK

E2F2

201

Q14209
LEPQGQTQTKLVPRQ

C3P1

136

Q6ZMU1
QPVPPENGFIRNEKQ

C6

646

P13671
INKNQVPPPSTRALL

DMKN

376

Q6E0U4
NLQPKPIGVGIPTIN

CACNA2D1

526

P54289
LQKGDQRQVIPIPSP

CTDSPL

76

O15194
PANGQTPIQRTIKPD

FN1

1941

P02751
QLPPVNRSLKPNQKA

GAB4

416

Q2WGN9
IPVPPNGENQTLERL

COL6A5

1921

A8TX70
RQQQQLLQPRPSPVG

CELF5

11

Q8N6W0
GLQRVQLLKPNIPEP

DBH

191

P09172
APLNRKGLVSPQSPQ

BCL6

321

P41182
PQTIKRPLNPLASGQ

ERO1A

211

Q96HE7
PPPHLKTQLEINGRN

MBNL1

71

Q9NR56
QQRPVPESQLLPGQR

LYN

41

P07948
PLQPPQQSIRVKEEQ

MIDEAS

31

Q6PJG2
KPPSGNKQQLPLVNE

CCDC38

536

Q502W7
PGSNPNKRQRQPPLL

HNRNPL

296

P14866
GPKPGPVVRNEKIQN

ENAM

421

Q9NRM1
LDNQKLVPQPRVPPV

EMC9

116

Q9Y3B6
EGINLNPVPSPNQKR

DCLRE1A

581

Q6PJP8
TPKQVQELGIPLTPQ

FAM186A

1256

A6NE01
PKQAQELGIPLNPQQ

FAM186A

1281

A6NE01
PQQAQELGIPLTPQQ

FAM186A

1461

A6NE01
PQAQELGIPLTPQQA

FAM186A

1486

A6NE01
QQVQALGIPLIPPQA

FAM186A

1546

A6NE01
PQQAQELGIPLTPQQ

FAM186A

1581

A6NE01
IPLTPQQAQAQGIPL

FAM186A

1601

A6NE01
PQTNLLAPKLQFQVP

PTK2B

726

Q14289
PTANGVKPLQEQPLA

ERICH5

71

Q6P6B1
PTLEPQKAQKPNGQL

B3GNT7

41

Q8NFL0
LRDSGQPPQQREQPL

CDH15

561

P55291
AQEPPGVENIPRQIL

FAM166A

111

Q6J272
PQEKVPLFRVTQQGP

LRRN4

21

Q8WUT4
QLKLPGQNPLPLNLE

NYNRIN

401

Q9P2P1
IQVNPLGIPVNSKEP

MCAM

141

P43121
PKPLKGQAQAPQRLQ

NRK

426

Q7Z2Y5
KQLGPQVQQIILVSP

USO1

151

O60763
PPQNPRKLILAGNII

SLITRK6

361

Q9H5Y7
GAQQQKQLRIPEPPN

SPATA22

151

Q8NHS9
GQTVPRALQILPQIP

TAB3

206

Q8N5C8
HRGILQQLLPPNQVK

TDRD15

306

B5MCY1
GNQKPRITIIPSPNV

FILIP1

946

Q7Z7B0
VEPQKPSLPNQQGIG

RESF1

921

Q9HCM1
QKVVTRFPPVPQQQL

ST6GALNAC1

336

Q9NSC7
LQKRVNQSENSVPPP

SHTN1

341

A0MZ66
QKQQGPLPAPLNDSE

TANC1

1426

Q9C0D5
EPVAQPGLLLQPSKQ

TANC1

1516

Q9C0D5
SNLPQLQNLIKRDPP

SDAD1

11

Q9NVU7
QNEGVQLLPSKKQPP

SPATA31C1

996

P0DKV0
GVPIVPQSQQGKPLR

STXBP3

446

O00186
TPQGAPQVSQPLREQ

STK36

636

Q9NRP7
QVGPQPLLTIPNDTK

SMCR8

66

Q8TEV9
QAIAKQPINRGQPKP

APC

1911

P25054
QPINRGQPKPILQKQ

APC

1916

P25054
LQPKAKAQQTQPPGL

CD300LG

146

Q6UXG3
VPVQNGAQPPSKIIQ

CIC

951

Q96RK0
QSQEPLKPQENISRP

C12orf50

61

Q8NA57
KEPPGQLQVKAQPQA

CIZ1

271

Q9ULV3
APLVAGPKLPAQQQR

C11orf16

121

Q9NQ32
QNQNLPVAKLPPSKL

PICALM

521

Q13492
LKQILSAPLPRQQGP

TIMELESS

646

Q9UNS1
KLQPELQPKVPGEQG

TIMELESS

1106

Q9UNS1
AARVQIPPAQKSVPQ

PLEKHA6

156

Q9Y2H5
VPQGQRPPPRIKNFQ

ZDHHC9

116

Q9Y397
RPPPRIKNFQINNQI

ZDHHC9

121

Q9Y397
GSQPAPVRKNQLLPS

MINDY4

351

Q4G0A6
QPGLERAQQELVPPQ

SEC16A

1051

O15027
LQGKRLGQLQPLPQT

RIPOR3

806

Q96MK2
VFQQLENILPGLPQP

RNLS

266

Q5VYX0
PQEPSNKVPEQQRQI

TPR

1631

P12270
RENSQPQELQKPQEP

SLCO4C1

41

Q6ZQN7
KSNPNLRATGQRPPI

PLCH2

1201

O75038
KKPPLVQRNNPVLND

STPG4

81

Q8N801
QQENPPLPLGSKVVV

SPINT2

186

O43291
PNQLRQDNRQIHPPK

SCEL

201

O95171
VPTGKKQVPLNPDLN

SUZ12

206

Q15022
KQVPLNPDLNQTKPG

SUZ12

211

Q15022
RRLQQIKEGPPPQNS

RLIM

66

Q9NVW2
LAEELPPQPQLQQQG

TRIL

446

Q7L0X0
KPVLPPINPQRQNGL

SUFU

321

Q9UMX1
VVLPQRAPQGQPQML

USP49

126

Q70CQ1
PQPGLQKSVSNLQKP

PRRC2B

111

Q5JSZ5
QKPIPRPLNKIQGIV

SCN8A

1501

Q9UQD0
QVFVTEQNPRPPKNR

SIRPD

136

Q9H106
AEGLPQQQQLPQLEP

PPP1R3F

296

Q6ZSY5
RISQNTGPPPIDRQK

USF3

1776

Q68DE3
QELPPEEQGPSIRNL

UNC13B

951

O14795
GPPRKDKNLPNVIIN

UTP14A

656

Q9BVJ6
QGAQARPPPEQLKVF

ARHGAP31

421

Q2M1Z3
RPTLQEGPGLQQKPR

TBC1D22A

111

Q8WUA7
EQHRGQPLPPDLLQQ

CAD

851

P27708
KPQSFQVILQLPPQQ

SYMPK

1046

Q92797
PPLKVIQPNGNQDER

ZEB1

856

P37275
QLTPPQQTRVGEKPA

ZNF251

636

Q9BRH9
QRNVAPGIFKQRPPI

USP24

2356

Q9UPU5
VTQPPQPGAIRKLLN

TRAPPC8

76

Q9Y2L5
VNANDPPPISGKNLR

TBC1D20

76

Q96BZ9
RAPNGPEANPVKQLQ

PIEZO1

2361

Q92508
RQPLPTGLQKKRQPG

VPS33A

526

Q96AX1
QPLRVNSQPGPQKRC

UBASH3B

371

Q8TF42
RPPKSGQEPPLVQVQ

ZNF524

56

Q96C55
GRGVQPEPQLQQLKT

VPS9D1

396

Q9Y2B5
SQGPIPFQQQKTPLL

WDR33

896

Q9C0J8
QQKPPTRVLPKQGIL

VEZT

46

Q9HBM0
LEPQLGSPQQKPKRL

VWA8

1701

A3KMH1
QPVPSIKNVPQIDRT

USP8

396

P40818
EKGLESLPPLRPQQN

MARS1

241

P56192
QKQQITLQPTPGLPS

HIVEP1

2361

P15822
VPDDGLPLQSQQLPQ

TFIP11

291

Q9UBB9
RINLQQQPPPLQIKS

TOX4

481

O94842
LNPQKPGAIDNQPLV

USP32

516

Q8NFA0
GDSQLLLVQPQPQPQ

KMT2D

4071

O14686
PQEKNNGPKVPVELR

MYOF

821

Q9NZM1
EQLNLVVPFQGKPRP

MYBPC2

856

Q14324
VNLLIPFQGKPRPQV

MYBPC3

991

Q14896