Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ATF7 ZNF384 SP1 SP3 ZNF280C ZNF507 WT1 ZBTB9 ZNF280B E4F1 ZNF236 ZNF260 ZNF711 TBX18 SAFB ZBTB39 SALL2 WIZ SMARCA4 ZFHX2 SP5 PLAG1 KLF17

1.63e-0812449623GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ATF7 ZNF384 SP1 SP3 ZNF280C ZNF507 WT1 ZBTB9 ZNF280B E4F1 ZNF236 ZNF260 ZNF711 TBX18 SAFB ZBTB39 SALL2 WIZ SMARCA4 ZFHX2 SP5 PLAG1 KLF17

2.43e-0812719623GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF438 ATF7 ZNF384 SP1 SP3 ZNF280C ZNF507 WT1 ZBTB9 ZNF280B E4F1 ZNF236 ZNF260 ZNF711 RLF TBX18 ZBTB39 SALL2 WIZ ZNF451 ZFHX2 SP5 PLAG1 KLF17

3.71e-0814129624GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ATF7 ZNF384 SP1 SP3 ZNF280C ZNF507 WT1 ZBTB9 ZNF280B E4F1 ZNF236 ZNF260 ZNF711 TBX18 SAFB ZBTB39 SALL2 WIZ SMARCA4 ZFHX2 SP5 PLAG1 KLF17

2.96e-0714599623GO:0000977
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

SMARCAD1 SUPV3L1 SMARCA2 SMARCA4 ASCC3

3.70e-04127965GO:0008094
GeneOntologyMolecularFunctionmicrotubule binding

KIF27 CENPE CEP290 LRRK2 CCDC66 KIF15 TIAM1

7.16e-04308967GO:0008017
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

SMARCAD1 SMARCA2 SMARCA4

7.43e-0437963GO:0140658
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

ATF7 SP3 E4F1 TBX18 ZBTB39 SP5 KLF17

8.96e-04320967GO:0001227
GeneOntologyMolecularFunctionhelicase activity

SMARCAD1 SUPV3L1 SMARCA2 SMARCA4 ASCC3

9.97e-04158965GO:0004386
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

ATF7 SP3 E4F1 TBX18 ZBTB39 SP5 KLF17

9.98e-04326967GO:0001217
GeneOntologyMolecularFunctioncAMP response element binding

ATF7 E4F1

1.46e-0312962GO:0035497
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

APTX SMARCAD1 SUPV3L1 SMARCA2 SMARCA4 ASCC3

1.67e-03262966GO:0140097
GeneOntologyMolecularFunctioncytoskeletal protein binding

NRAP KIF27 CENPE SYNE1 COBLL1 CEP290 LRRK2 LMTK2 FHOD3 CCDC66 KIF15 TIAM1 FGD4

2.28e-0310999613GO:0008092
GeneOntologyMolecularFunctionprotein kinase A binding

LRRK2 NBEA SPHKAP

2.74e-0358963GO:0051018
GeneOntologyMolecularFunctionATP-dependent activity

KIF27 CENPE CFTR SMARCAD1 KIF15 SUPV3L1 SMARCA2 SMARCA4 ASCC3

2.79e-03614969GO:0140657
GeneOntologyMolecularFunctionC2H2 zinc finger domain binding

WT1 ZXDA

2.97e-0317962GO:0070742
GeneOntologyMolecularFunctiontubulin binding

KIF27 CENPE CEP290 LRRK2 CCDC66 KIF15 TIAM1

4.59e-03428967GO:0015631
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF27 CENPE KIF15

4.67e-0370963GO:0003777
GeneOntologyMolecularFunctiontranscription coregulator binding

ATF7 SP1 WIZ SMARCA4

4.67e-03140964GO:0001221
DomainZINC_FINGER_C2H2_2

ZNF438 ATF7 ZNF384 SP1 SP3 APTX ZNF280C ZNF507 WT1 ZBTB9 ZNF407 ZNF280B E4F1 ZNF236 ZNF804A ZXDA ZNF260 ZNF711 RLF ZBTB39 SALL2 WIZ ZNF451 ZFHX2 SP5 PLAG1 KLF17

8.18e-167759527PS50157
DomainZINC_FINGER_C2H2_1

ZNF438 ATF7 ZNF384 SP1 SP3 APTX ZNF280C ZNF507 WT1 ZBTB9 ZNF407 ZNF280B E4F1 ZNF236 ZNF804A ZXDA ZNF260 ZNF711 RLF ZBTB39 SALL2 WIZ ZNF451 ZFHX2 SP5 PLAG1 KLF17

8.72e-167779527PS00028
DomainZnf_C2H2-like

ZNF438 ATF7 ZNF384 SP1 SP3 APTX ZNF280C ZNF507 WT1 ZBTB9 ZNF407 ZNF280B E4F1 ZNF236 ZNF804A ZXDA ZNF260 ZNF711 RLF ZBTB39 SALL2 WIZ ZNF451 ZFHX2 SP5 PLAG1 KLF17

1.58e-157969527IPR015880
DomainZnf_C2H2

ZNF438 ATF7 ZNF384 SP1 SP3 APTX ZNF280C ZNF507 WT1 ZBTB9 ZNF407 ZNF280B E4F1 ZNF236 ZNF804A ZXDA ZNF260 ZNF711 RLF ZBTB39 SALL2 WIZ ZNF451 ZFHX2 SP5 PLAG1 KLF17

2.08e-158059527IPR007087
DomainZnF_C2H2

ZNF438 ATF7 ZNF384 SP1 SP3 APTX ZNF280C ZNF507 WT1 ZBTB9 ZNF407 ZNF280B E4F1 ZNF236 ZNF804A ZXDA ZNF260 ZNF711 RLF ZBTB39 SALL2 WIZ ZNF451 ZFHX2 SP5 PLAG1 KLF17

2.28e-158089527SM00355
Domain-

ZNF438 ATF7 ZNF384 SP1 SP3 ZNF507 WT1 ZBTB9 ZNF407 E4F1 ZNF236 ZXDA ZNF260 ZNF711 RLF ZBTB39 SALL2 ZFHX2 SP5 PLAG1 KLF17

2.13e-1167995213.30.160.60
Domainzf-C2H2

ZNF438 ATF7 ZNF384 SP1 SP3 ZNF507 WT1 ZBTB9 ZNF407 E4F1 ZNF236 ZXDA ZNF260 ZNF711 RLF ZBTB39 SALL2 ZNF451 ZFHX2 SP5 KLF17

3.11e-116939521PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF438 ATF7 ZNF384 SP1 SP3 ZNF507 WT1 ZBTB9 ZNF407 E4F1 ZNF236 ZXDA ZNF260 ZNF711 RLF ZBTB39 SALL2 ZFHX2 SP5 PLAG1 KLF17

3.20e-116949521IPR013087
DomainSp1_fam

SP1 SP3 SP5

1.49e-0510953IPR030450
DomainSnAC

SMARCA2 SMARCA4

2.56e-052952SM01314
DomainGln-Leu-Gln_QLQ

SMARCA2 SMARCA4

2.56e-052952IPR014978
DomainSnAC

SMARCA2 SMARCA4

2.56e-052952IPR029295
DomainSnAC

SMARCA2 SMARCA4

2.56e-052952PF14619
DomainQLQ

SMARCA2 SMARCA4

2.56e-052952SM00951
DomainQLQ

SMARCA2 SMARCA4

2.56e-052952PS51666
DomainQLQ

SMARCA2 SMARCA4

2.56e-052952PF08880
DomainHSA

SMARCA2 SMARCA4

1.53e-044952SM00573
DomainDUF4195

ZNF280C ZNF280B

1.53e-044952PF13836
DomainHSA

SMARCA2 SMARCA4

1.53e-044952PS51204
DomainHSA_dom

SMARCA2 SMARCA4

1.53e-044952IPR014012
DomainDUF4195

ZNF280C ZNF280B

1.53e-044952IPR025243
DomainHSA

SMARCA2 SMARCA4

1.53e-044952PF07529
DomainHelicase_C

SMARCAD1 SUPV3L1 SMARCA2 SMARCA4 ASCC3

2.16e-04107955PF00271
DomainHELICc

SMARCAD1 SUPV3L1 SMARCA2 SMARCA4 ASCC3

2.16e-04107955SM00490
DomainHelicase_C

SMARCAD1 SUPV3L1 SMARCA2 SMARCA4 ASCC3

2.26e-04108955IPR001650
DomainHELICASE_CTER

SMARCAD1 SUPV3L1 SMARCA2 SMARCA4 ASCC3

2.36e-04109955PS51194
DomainHELICASE_ATP_BIND_1

SMARCAD1 SUPV3L1 SMARCA2 SMARCA4 ASCC3

2.36e-04109955PS51192
DomainBRK

SMARCA2 SMARCA4

3.79e-046952SM00592
DomainBRK_domain

SMARCA2 SMARCA4

3.79e-046952IPR006576
DomainBRK

SMARCA2 SMARCA4

3.79e-046952PF07533
DomainSNF2_N

SMARCAD1 SMARCA2 SMARCA4

5.68e-0432953IPR000330
DomainSNF2_N

SMARCAD1 SMARCA2 SMARCA4

5.68e-0432953PF00176
DomainKinesin-like_fam

KIF27 CENPE KIF15

1.36e-0343953IPR027640
DomainKINESIN_MOTOR_1

KIF27 CENPE KIF15

1.45e-0344953PS00411
Domain-

KIF27 CENPE KIF15

1.45e-03449533.40.850.10
DomainKinesin_motor_dom

KIF27 CENPE KIF15

1.45e-0344953IPR001752
DomainKinesin

KIF27 CENPE KIF15

1.45e-0344953PF00225
DomainKINESIN_MOTOR_2

KIF27 CENPE KIF15

1.45e-0344953PS50067
DomainKISc

KIF27 CENPE KIF15

1.45e-0344953SM00129
DomainSSD

HMGCR PTCHD1

1.93e-0313952IPR000731
DomainSSD

HMGCR PTCHD1

1.93e-0313952PS50156
DomainDEXDc

SMARCAD1 SMARCA2 SMARCA4 ASCC3

2.32e-03109954SM00487
DomainHelicase_ATP-bd

SMARCAD1 SMARCA2 SMARCA4 ASCC3

2.40e-03110954IPR014001
DomainP-loop_NTPase

KIF27 CENPE CFTR LRRK2 SMARCAD1 TRANK1 KIF15 SUPV3L1 SMARCA2 SMARCA4 ASCC3

3.82e-038489511IPR027417
PathwayBIOCARTA_TERT_PATHWAY

SP1 SP3 WT1

2.06e-067563MM1541
PathwayBIOCARTA_TERT_PATHWAY

SP1 SP3 WT1

3.28e-068563M22015
PathwayWP_ESTRADIOL_REGULATION_IN_PORTOSINUSOIDAL_VASCULAR_DISEASE

SP1 SP3

1.54e-045562M45554
PathwayBIOCARTA_TERC_PATHWAY

SP1 SP3

2.30e-046562MM1564
PathwayBIOCARTA_TERC_PATHWAY

SP1 SP3

2.30e-046562M22047
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF438 ATF7 SP1 SP3 NRAP ZNF280C ZNF507 WT1 ZNF280B ZNF236 ZNF260 WIZ ZNF451 SMARCA2 PLAG1 KLF17 KAT6B

9.45e-11808971720412781
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SYNE1 ZNF407 FHOD3 GREB1L ZNF451 SPHKAP DCLK3 ZFHX2

4.82e-1010297811214970
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

GAPVD1 ERC1 ZNF507 ZBTB9 RNF40 GREB1L RLF SALL2 WIZ KIF15 ASCC3

2.61e-08418971134709266
Pubmed

A census of human transcription factors: function, expression and evolution.

ATF7 ZNF384 SP1 SP3 WT1 E4F1 ZNF236 ZNF711 TBX18 SALL2 ZNF451 ZFHX2 SP5 PLAG1

2.32e-07908971419274049
Pubmed

Nkx3.1 binds and negatively regulates the transcriptional activity of Sp-family members in prostate-derived cells.

SP1 SP3 SP5

4.18e-07697316201967
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

SP1 SP3 WT1 E4F1 RLF SALL2 SMARCA2 SMARCA4 ZFHX2 PLAG1 KLF17 KAT6B

6.89e-07709971222988430
Pubmed

Loss of Rearranged L-Myc Fusion (RLF) results in defects in heart development in the mouse.

SP3 WT1 RLF SMARCA4

3.90e-063897427930960
Pubmed

Synphilin-1 attenuates mutant LRRK2-induced neurodegeneration in Parkinson's disease models.

SP1 LRRK2

7.70e-06297226744328
Pubmed

The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

SMARCA2 SMARCA4

7.70e-0629728670841
Pubmed

Sp1 increases expression of cyclooxygenase-2 in hypoxic vascular endothelium. Implications for the mechanisms of aortic aneurysm and heart failure.

SP1 SP3

7.70e-06297210825178
Pubmed

HPV8 activates cellular gene expression mainly through Sp1/3 binding sites.

SP1 SP3

7.70e-06297231299490
Pubmed

Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.

SMARCA2 SMARCA4

7.70e-06297223163725
Pubmed

Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.

SMARCA2 SMARCA4

7.70e-06297223076393
Pubmed

Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and platelet formation and function.

SP1 SP3

7.70e-06297225538045
Pubmed

The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.

SMARCA2 SMARCA4

7.70e-06297215576411
Pubmed

Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.

SMARCA2 SMARCA4

7.70e-06297215240517
Pubmed

Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.

SMARCA2 SMARCA4

7.70e-06297226564006
Pubmed

SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.

SMARCA2 SMARCA4

7.70e-06297233027072
Pubmed

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

SMARCA2 SMARCA4

7.70e-06297223872584
Pubmed

Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors.

SP1 SP3

7.70e-06297231164147
Pubmed

Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.

SMARCA2 SMARCA4

7.70e-06297223088494
Pubmed

SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.

SMARCA2 SMARCA4

7.70e-06297220333683
Pubmed

SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.

SMARCA2 SMARCA4

7.70e-06297234812766
Pubmed

Transcriptional activity and Sp 1/3 transcription factor binding to the P1 promoter sequences of the human AbetaH-J-J locus.

SP1 SP3

7.70e-06297217681019
Pubmed

Endothelial Sp1/Sp3 are essential to the effect of captopril on blood pressure in male mice.

SP1 SP3

7.70e-06297237735515
Pubmed

Sp1 and Sp3 Are the Transcription Activators of Human ek1 Promoter in TSA-Treated Human Colon Carcinoma Cells.

SP1 SP3

7.70e-06297226807725
Pubmed

Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.

SMARCA2 SMARCA4

7.70e-06297230478150
Pubmed

Sp1/Sp3-dependent regulation of human telomerase reverse transcriptase promoter activity by the bioactive sphingolipid ceramide.

SP1 SP3

7.70e-06297215951564
Pubmed

Transcription factors Sp1 and Sp3 regulate basal transcription of the human IRF-3 gene.

SP1 SP3

7.70e-06297222464952
Pubmed

The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.

SMARCA2 SMARCA4

7.70e-06297225808524
Pubmed

Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3.

SP1 SP3

7.70e-0629728845379
Pubmed

Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.

SMARCA2 SMARCA4

7.70e-06297219144648
Pubmed

Regulation of LRRK2 promoter activity and gene expression by Sp1.

SP1 LRRK2

7.70e-06297227004687
Pubmed

High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.

SMARCA2 SMARCA4

7.70e-06297229391527
Pubmed

Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and construction of a nomogram prognostic model.

SMARCA2 SMARCA4

7.70e-06297237634210
Pubmed

Expression of the human endogenous retrovirus (HERV) group HML-2/HERV-K does not depend on canonical promoter elements but is regulated by transcription factors Sp1 and Sp3.

SP1 SP3

7.70e-06297221248046
Pubmed

Sp1 and Sp3 activate transcription of the human dopamine transporter gene.

SP1 SP3

7.70e-06297215816870
Pubmed

Sp family transcription factors regulate expression of rat D2 dopamine receptor gene.

SP1 SP3

7.70e-0629729628590
Pubmed

Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.

SMARCA2 SMARCA4

7.70e-0629728208605
Pubmed

The nuclear abundance of transcription factors Sp1 and Sp3 depends on biotin in Jurkat cells.

SP1 SP3

7.70e-06297214608051
Pubmed

A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.

SMARCA2 SMARCA4

7.70e-06297211163203
Pubmed

Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.

SMARCA2 SMARCA4

7.70e-06297212620226
Pubmed

BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.

SMARCA2 SMARCA4

7.70e-06297227039070
Pubmed

Partial Inactivation of the Chromatin Remodelers SMARCA2 and SMARCA4 in Virus-Infected Cells by Caspase-Mediated Cleavage.

SMARCA2 SMARCA4

7.70e-06297229848589
Pubmed

Differentiation-dependent and cell-specific regulation of the hIGFBP-1 gene in human endometrium.

SP1 SP3

7.70e-0629729329821
Pubmed

Concentration-dependent effects of endogenous S-nitrosoglutathione on gene regulation by specificity proteins Sp3 and Sp1.

SP1 SP3

7.70e-06297214766015
Pubmed

Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.

SMARCA2 SMARCA4

7.70e-0629729603422
Pubmed

Hemogen/BRG1 cooperativity modulates promoter and enhancer activation during erythropoiesis.

HEMGN SMARCA4

7.70e-06297235297980
Pubmed

SWI/SNF gene variants and glioma risk and outcome.

SMARCA2 SMARCA4

7.70e-06297223276717
Pubmed

Differential Expression of SWI/SNF Chromatin Remodeler Subunits Brahma and Brahma-Related Gene During Drug-Induced Liver Injury and Regeneration in Mouse Model.

SMARCA2 SMARCA4

7.70e-06297227097303
Pubmed

SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.

SMARCA2 SMARCA4

7.70e-06297228038711
Pubmed

Proinflammatory stimuli engage Brahma related gene 1 and Brahma in endothelial injury.

SMARCA2 SMARCA4

7.70e-06297223963727
Pubmed

SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level.

SMARCA2 SMARCA4

7.70e-06297212493776
Pubmed

Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4.

SMARCA2 SMARCA4

7.70e-06297231375262
Pubmed

Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.

SMARCA2 SMARCA4

7.70e-06297217075831
Pubmed

An Sp1/Sp3 binding polymorphism confers methylation protection.

SP1 SP3

7.70e-06297218725933
Pubmed

Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.

SMARCA2 SMARCA4

7.70e-06297232855269
Pubmed

Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.

SMARCA2 SMARCA4

7.70e-06297222721696
Pubmed

Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter.

SMARCA2 SMARCA4

7.70e-06297218508913
Pubmed

Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.

SMARCA2 SMARCA4

7.70e-06297211719516
Pubmed

Sp1 and Sp3 regulate transcription of the cyclin-dependent kinase 5 regulatory subunit 2 (p39) promoter in neuronal cells.

SP1 SP3

7.70e-06297219437621
Pubmed

DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes.

SMARCA2 SMARCA4

7.70e-06297228706277
Pubmed

[Expression of BRG1 and BRM proteins in prostatic cancer].

SMARCA2 SMARCA4

7.70e-06297221092585
Pubmed

SWI/SNF Complex-deficient Undifferentiated/Rhabdoid Carcinomas of the Gastrointestinal Tract: A Series of 13 Cases Highlighting Mutually Exclusive Loss of SMARCA4 and SMARCA2 and Frequent Co-inactivation of SMARCB1 and SMARCA2.

SMARCA2 SMARCA4

7.70e-06297226551623
Pubmed

Transcriptional control of human CD2AP expression: the role of Sp1 and Sp3.

SP1 SP3

7.70e-06297221604172
Pubmed

SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity.

SMARCA2 SMARCA4

7.70e-06297219458193
Pubmed

Maximal induction of a subset of interferon target genes requires the chromatin-remodeling activity of the BAF complex.

SP1 SMARCA4

7.70e-06297212192045
Pubmed

The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation.

SMARCA2 SMARCA4

7.70e-06297234289068
Pubmed

SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.

SMARCA2 SMARCA4

7.70e-06297234518526
Pubmed

SMARCA family of genes.

SMARCA2 SMARCA4

7.70e-06297232312722
Pubmed

Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.

SMARCA2 SMARCA4

7.70e-06297226356327
Pubmed

Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness.

SP1 SMARCA4

7.70e-06297220969766
Pubmed

Loss of BRG1/BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis.

SMARCA2 SMARCA4

7.70e-06297212566296
Pubmed

SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines.

SMARCA2 SMARCA4

7.70e-06297231406271
Pubmed

Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits.

SMARCA2 SMARCA4

7.70e-06297229273066
Pubmed

LMTK2-mediated phosphorylation regulates CFTR endocytosis in human airway epithelial cells.

CFTR LMTK2

7.70e-06297224727471
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZNF384 ZNF280C ZBTB9 SMARCAD1 ZNF711 RLF WIZ ZNF451 SMARCA4 BOD1L1

7.97e-06608971036089195
Pubmed

BRG1-SWI/SNF-dependent regulation of the Wt1 transcriptional landscape mediates epicardial activity during heart development and disease.

WT1 SMARCA2 SMARCA4

9.34e-061597328737171
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

RABEP2 FLT1 GAPVD1 CENPE NBEA TRANK1 KIF15 PLCB4 ASCC3

1.09e-0549797936774506
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

CEP290 ZBTB39 TRANK1 SALL2 KAT6B

1.12e-051049759205841
Pubmed

An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse.

RLF WIZ SMARCA4

1.66e-051897324025402
Pubmed

Thymosin beta 4 is dispensable for murine cardiac development and function.

FLT1 WT1 TBX18

1.66e-051897322158707
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ERC1 SYNE1 SMARCAD1 ZNF451 SPHKAP BOD1L1 LRRC7 ADGRL3

1.91e-0540797812693553
Pubmed

Expression patterns of SP1 and SP3 during mouse spermatogenesis: SP1 down-regulation correlates with two successive promoter changes and translationally compromised transcripts.

SP1 SP3

2.31e-05397218417714
Pubmed

Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1.

SP1 SP3

2.31e-05397214701757
Pubmed

Regulation of the human secretin gene is controlled by the combined effects of CpG methylation, Sp1/Sp3 ratio, and the E-box element.

SP1 SP3

2.31e-05397215118068
Pubmed

Modulation of Bone Morphogenetic Protein (BMP) 2 gene expression by Sp1 transcription factors.

SP1 SP3

2.31e-05397217317039
Pubmed

In vivo footprinting of the human 11beta-hydroxysteroid dehydrogenase type 2 promoter: evidence for cell-specific regulation by Sp1 and Sp3.

SP1 SP3

2.31e-05397211850421
Pubmed

DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1.

SMARCA2 SMARCA4

2.31e-05397230287812
Pubmed

Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice.

SP1 SP3

2.31e-05397236759621
Pubmed

Sp1/3 and NF-1 mediate basal transcription of the human P2X1 gene in megakaryoblastic MEG-01 cells.

SP1 SP3

2.31e-05397216529657
Pubmed

Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence.

SP1 SP3

2.31e-05397223028678
Pubmed

Sp proteins and Runx2 mediate regulation of matrix gla protein (MGP) expression by parathyroid hormone.

SP1 SP3

2.31e-05397219306294
Pubmed

Identification of an Sp factor-dependent promoter in GCET, a gene expressed at high levels in germinal center B cells.

SP1 SP3

2.31e-05397215482850
Pubmed

Structural and functional characterization of the mouse tescalcin promoter.

SP1 SP3

2.31e-05397220540995
Pubmed

Transcriptional regulation of the human CD97 promoter by Sp1/Sp3 in smooth muscle cells.

SP1 SP3

2.31e-05397218329191
Pubmed

Human glycolipid transfer protein gene (GLTP) expression is regulated by Sp1 and Sp3: involvement of the bioactive sphingolipid ceramide.

SP1 SP3

2.31e-05397220974858
Pubmed

Histone deacetylase inhibition is associated with transcriptional repression of the Hmga2 gene.

SP1 SP3

2.31e-05397212799440
Pubmed

The constitutive expression of anticoagulant protein S is regulated through multiple binding sites for Sp1 and Sp3 transcription factors in the protein S gene promoter.

SP1 SP3

2.31e-05397216672217
Pubmed

Transcription of the LAT gene is regulated by multiple binding sites for Sp1 and Sp3.

SP1 SP3

2.31e-05397218343609
InteractionHDAC1 interactions

RABEP2 SP1 SP3 GAPVD1 ERC1 ZNF507 ZBTB9 RNF40 SMARCAD1 E4F1 RLF WIZ KIF15 CEP250 SMARCA2 SMARCA4 ASCC3 HECTD1

4.95e-0611089718int:HDAC1
InteractionPHF21A interactions

SP3 GAPVD1 ERC1 ZNF507 ZBTB9 RNF40 RLF SALL2 KIF15 ASCC3

6.06e-063439710int:PHF21A
InteractionKDM1A interactions

GAPVD1 ERC1 ZNF280C ZNF507 ZBTB9 RNF40 SMARCAD1 GREB1L RLF ZBTB39 SALL2 WIZ KIF15 ZNF451 SMARCA2 ASCC3

1.02e-059419716int:KDM1A
InteractionWHAMMP3 interactions

ATF7 CENPE SYNE1 RNF40 CEP250 PIBF1

2.38e-05119976int:WHAMMP3
InteractionCCDC110 interactions

CFTR CEP290 RLF

3.79e-0514973int:CCDC110
InteractionPCM1 interactions

CENPE ERC1 ZNF280C CEP290 CCDC66 KIF15 CEP250 PIBF1 COG5 CFAP97

4.58e-054349710int:PCM1
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF438 ZNF384 SP1 SP3 ZNF507 WT1 ZBTB9 ZNF407 E4F1 ZNF236 ZXDA ZNF260 ZNF711 RLF ZBTB39 SALL2 WIZ ZNF451 ZFHX2 SP5 PLAG1 KLF17

8.39e-16718622228
GeneFamilyZinc fingers C2H2-type|Sp transcription factors

SP1 SP3 SP5

3.18e-069623755
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF27 CENPE KIF15

5.25e-0446623622
GeneFamilyX-linked mental retardation|RNA helicases

SUPV3L1 ASCC3

6.24e-04116221168
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

NBEA SPHKAP

4.43e-0329622396
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SP3 GAPVD1 CENPE ERC1 ZNF804A RLF SGMS1 TIAM1 ZNF451 SMARCA2 PLCB4 ASCC3 PIBF1 KAT6B COG5

5.80e-078569715M4500
CoexpressionLAKE_ADULT_KIDNEY_C16_COLLECTING_SYSTEM_PRINCIPAL_CELLS_CORTEX

ERC1 COBLL1 FHOD3 NBEA SMARCA2 SPAG16

1.44e-05141976M39235
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000

SP1 SP3 GAPVD1 CENPE CEP290 HEMGN HMGCR SMARCAD1 ZNF804A ZNF711 RLF TBX18 ZNF451 SPHKAP SMARCA4 CFAP97

7.18e-078159616gudmap_developingGonad_e11.5_ovary + mesonephros_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

SPATA7 SP3 PDE3B CENPE ERC1 CEP290 FHOD3 HMGCR SMARCAD1 NMNAT3 ZNF711 CCDC66 KIF15 OSGEPL1 PPP1R16B BOD1L1 PLCB4 DBR1

1.09e-0610609618facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000

SP1 SP3 GAPVD1 CENPE CEP290 WT1 HEMGN ZNF711 GREB1L RLF ZNF451 SPHKAP SMARCA4 CFAP97

1.49e-058049614gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

SPATA7 SP3 PDE3B CENPE ERC1 CEP290 FHOD3 HMGCR SMARCAD1 ZNF804A NMNAT3 ZNF711 CCDC66 KIF15 OSGEPL1 PPP1R16B BOD1L1 PLCB4 DBR1

1.59e-0514149619facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5

CENPE WDR33 CEP290 FHOD3 CCDC66 BOD1L1 PIBF1

2.18e-05186967Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

CENPE CEP290 SAFB CCDC66 KIF15 BOD1L1 PIBF1 HECTD1

8.40e-05311968Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_1000

SP3 CENPE CEP290 ZNF711 GREB1L RLF CFAP97

9.11e-05233967gudmap_developingGonad_e12.5_ovary_k5_1000
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_500

SP1 SP3 HEMGN ZNF804A ZNF711 RLF TBX18 SPHKAP SMARCA4

1.14e-04417969gudmap_developingGonad_e11.5_ovary + mesonephros_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

PDE3B CENPE CEP290 FHOD3 SMARCAD1 RLF SAFB KIF15 ASCC3 PIBF1

1.47e-045329610Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

PDE3B CENPE CEP290 FHOD3 HMGCR SMARCAD1 ZNF711 PLEK2 CCDC66 KIF15 OSGEPL1 SUPV3L1 BOD1L1 DBR1 PIBF1 CFAP97

1.54e-0412579616facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

PDE3B DENND4A CENPE CEP290 FHOD3 NBEA SAFB CCDC66 KIF15 FGD4 KAT6B

1.79e-046549611Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 LRRK2 FHOD3 RHEX SGMS1 FGD4 SPAG16

2.55e-071979777e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B ERC1 COBLL1 FHOD3 GREB1L SPAG16

3.03e-06183976b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellControl-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

FLT1 PDE3B SYNE1 COBLL1 PON2 ADGRL3

3.54e-0618897688b3415e33db81726dd29c1f50c886e057af50a0
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CEP290 FHOD3 ZNF804A PTCHD1 TRANK1 SPHKAP

3.88e-061919765d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CEP290 FHOD3 ZNF804A PTCHD1 TRANK1 SPHKAP

3.88e-0619197673dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERC1 COBLL1 FHOD3 GREB1L RHEX SPAG16

4.00e-061929760bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 PDE3B ERC1 SMARCA2 PLCB4 ADGRL3

4.12e-06193976aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 PDE3B ERC1 SMARCA2 PLCB4 ADGRL3

4.12e-06193976c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 PDE3B ERC1 SMARCA2 PLCB4 ADGRL3

4.12e-06193976e1d546165dcc2392f540162206852c4717d7306f
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 PDE3B ERC1 PPP1R16B PLCB4 ADGRL3

4.24e-061949760b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 LRRK2 FHOD3 RHEX FGD4 SPAG16

4.50e-061969766ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellCOVID-19_Mild-PLT_4|COVID-19_Mild / Disease Group and Platelet Clusters

ZNF438 DENND4A WDR33 HEMGN SGMS1 ZNF451

4.77e-061989763d8c33dba759df0974aeb2b9a6b5167ae7a18e1f
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ERC1 ZNF407 NBEA FGD4 PLCB4 COG5

4.91e-0619997694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

IDO1 CEP290 SGMS1 SMARCA2 BOD1L1 CFAP97

4.91e-06199976c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellIPF-Epithelial-Ionocyte|IPF / Disease state, Lineage and Cell class

CFTR FHOD3 THRSP PLCB4 ADGRL3

2.64e-05160975d65d19f4fae60836bfd4303a1bb7de34e9d83e35
ToppCellIPF-Epithelial-Ionocyte|World / Disease state, Lineage and Cell class

CFTR FHOD3 THRSP PLCB4 ADGRL3

2.72e-05161975f1cd5c938cdc08ad8995371b72493850a6cf277a
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE SYNE1 KIF15 PXT1 HSD11B1

2.98e-051649752a230ea066decb798a0e6f2b96c7608c8e608031
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE SYNE1 KIF15 PXT1 HSD11B1

2.98e-05164975d02d39edd0bfef5a53b814ec6d5f026d41253218
ToppCell11.5-Airway-RBC-RBC|Airway / Age, Tissue, Lineage and Cell class

TSGA13 HEMGN NMNAT3 PLEK2 RHEX

3.06e-051659758618b2c5659aa70c7c9d6e51a227ac612b4ad17b
ToppCell11.5-Airway-RBC|Airway / Age, Tissue, Lineage and Cell class

TSGA13 HEMGN NMNAT3 PLEK2 RHEX

3.06e-0516597546042340a373adaf1c439b2301e02fbae3e31a4f
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IDO1 PON2 ZNF711 RHEX ADGRL3

3.15e-05166975b1bebcbe17386cb102b11d551e62d46156ce0c68
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IDO1 PON2 ZNF711 RHEX ADGRL3

3.25e-05167975e44743b20a7435c579d8e999ddc4ca119d6753f2
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

PDE3B DENND4A SYNE1 ZNF407 KAT6B

3.63e-051719752e9a20f8980b78325c52065a9c14ab3656267c05
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 LRRK2 RLF TRANK1 FGD4

3.74e-05172975d354424c1f861b6607dfd63b9724f4c237b30275
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 ZNF711 THRSP COG5 ADGRL3

4.17e-0517697527e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 LRRK2 NMNAT3 RHEX ADGRL3

4.17e-05176975327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRRK2 GREB1L RHEX ZBTB39 ADGRL3

4.40e-05178975c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellNS-moderate-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFTR FHOD3 THRSP ANKRD30A ADGRL3

4.64e-051809758af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 LRRK2 NMNAT3 RHEX PLCB4

4.76e-051819759d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B ERC1 FHOD3 GREB1L FGD4

4.76e-05181975aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellwk_20-22-Hematologic-Meg-ery-Definitive_erythroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

GAPVD1 DENND4A HEMGN PLEK2 ZNF451

4.89e-051829750c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 LRRK2 NMNAT3 RHEX PLCB4

4.89e-05182975eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERC1 COBLL1 FHOD3 GREB1L SPAG16

5.28e-05185975d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATF7 FLT1 LRRK2 ZBTB39 SP5

5.28e-05185975bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCellfacs-Aorta-Heart-3m-Endothelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 THRSP SGMS1 PPP1R16B PLCB4

5.56e-05187975df0279b7e94e26f5541b0e2a0ce56befa96ec8ca
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LGI4 TBX18 PTCHD1 PLCB4 ADGRL3

5.70e-05188975b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCellfacs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 WT1 THRSP PPP1R16B PLCB4

5.70e-05188975ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 PDE3B PPP1R16B PLCB4 ADGRL3

5.70e-05188975789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 LRRK2 NMNAT3 RHEX ADGRL3

5.70e-0518897563a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellfacs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 WT1 THRSP PPP1R16B PLCB4

5.70e-05188975e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCellfacs-Heart-LV-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 WT1 THRSP PPP1R16B PLCB4

5.70e-051889750fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF804A TBX18 PTCHD1 LRRC7 ADGRL3

5.99e-051909752e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF804A TBX18 PTCHD1 LRRC7 ADGRL3

5.99e-051909750028f886c789ba238c031eae5d96acaed4af8c25
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLT1 SYNE1 COBLL1 PLCB4 ADGRL3

5.99e-051909750e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

NRAP FHOD3 GREB1L SPHKAP LRRC7

6.15e-051919755d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 WT1 THRSP SGMS1 PLCB4

6.15e-051919755020fe6c3452e7fab57847f5043d28ebbc5aa381
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 PDE3B PPP1R16B PLCB4 ADGRL3

6.30e-0519297504f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 PDE3B PPP1R16B PLCB4 ADGRL3

6.30e-051929750aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FHOD3 ZNF804A PTCHD1 TRANK1 SPHKAP

6.30e-051929754c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 PDE3B PPP1R16B PLCB4 ADGRL3

6.30e-05192975c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 PDE3B PPP1R16B PLCB4 ADGRL3

6.46e-05193975e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 PDE3B PPP1R16B PLCB4 ADGRL3

6.46e-051939756e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellMS-mDC1|MS / Condition, Cell_class and T cell subcluster

IDO1 LRRK2 PON2 ZNF711 RHEX

6.46e-051939754d08ebf555954d6a873a4b4c4d661dc5dd8a5bcb
ToppCellMS-mDC1-|MS / Condition, Cell_class and T cell subcluster

IDO1 LRRK2 PON2 ZNF711 RHEX

6.46e-05193975ce873f20b93e3b57c9385ee10d4becebe32ada06
ToppCellControl-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

FLT1 PON2 CALHM6 SMARCA2 PPP1R16B

6.46e-051939754cb938c346cc32ec122d11e6b9f25db20e0f7ff6
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFTR LRRK2 LMTK2 PON2 FGD4

6.46e-05193975a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 ERC1 PLCB4 ASCC3 HECTD1

6.61e-05194975e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 COBLL1 LRRK2 RHEX FGD4

6.61e-05194975e577d9e88390b36b5a09b97fe1026089892275a3
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NBEA HMGCR SPHKAP BOD1L1 ASCC3

6.78e-051959753e519cffa6144a62b06124642a14c9ff39b76554
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B DENND4A ZNF507 CCDC66 SUPV3L1

6.78e-05195975ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NBEA HMGCR SPHKAP BOD1L1 ASCC3

6.78e-051959757796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 COBLL1 CFTR LRRK2 HMGCR

6.94e-051969757e5addaa844e66f8160e05858c341866a80aed23
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF804A TBX18 PTCHD1 LRRC7 ADGRL3

6.94e-051969751522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLT1 PDE3B IDO1 SYNE1 PON2

6.94e-0519697549cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF804A TBX18 PTCHD1 LRRC7 ADGRL3

6.94e-051969751c8294014713684b50885e638668f2ce75f357f0
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

KIF27 LRRK2 SGMS1 FGD4 DBR1

7.11e-051979756b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 COBLL1 CFTR LRRK2 HMGCR

7.11e-05197975bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

COBLL1 CEP290 SMARCA2 BOD1L1 CFAP97

7.46e-0519997518a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCellMild/Remission-B_intermediate-0|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

COBLL1 LRRK2 ZNF804A PTCHD1 SUPV3L1

7.46e-05199975592111591f0f6816fc56620cb555eb48dabf0758
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 COBLL1 CFTR LRRK2 HMGCR

7.46e-051999752dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellLPS_IL1RA|World / Treatment groups by lineage, cell group, cell type

FLT1 IDO1 HMGCR ASCC3 ADGRL3

7.64e-05200975a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLT1 PDE3B IDO1 PLCB4 ADGRL3

7.64e-05200975105c67e4f5eff036013d655c8e8ac577d32dae2e
ToppCellLPS-IL1RA-Unknown-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WIZ KIF15 KLF17 PMFBP1

1.29e-04118974aefad0b35aff980b6a2a98057735442e8a65ab04
ToppCellLPS-IL1RA-Unknown|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WIZ KIF15 KLF17 PMFBP1

1.29e-041189746cb4063b83f867b782080ce5b1199b51bb277f2a
ToppCellLPS-IL1RA-Unknown-Endothelial-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTCHD1 WIZ KIF15 KLF17

1.61e-041259742938a1d62afe1e0a3abba5eb92f07b886cc0accd
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF711 PLEK2 TRANK1 LRRC7

2.55e-041419744aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF711 PLEK2 TRANK1 LRRC7

2.55e-04141974e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TSGA13 PTCHD1 SPHKAP ZFHX2

2.62e-04142974819e983688d126d89a71abc03d72525cc759a347
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF711 PLEK2 TRANK1 LRRC7

2.62e-04142974759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SUPV3L1 HSD11B1 DBR1 ADGRL3

2.62e-041429745690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCellP03-Hematopoietic-Erythroid|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HEMGN PLEK2 PXT1 PPP1R16B

2.77e-041449742ee6a834860eac7ed004f366ab4fc38c4b80c905
ToppCellP03-Hematopoietic-Erythroid-enucleate_erythrocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HEMGN PLEK2 PXT1 PPP1R16B

2.77e-041449749fa63904389f4d7163db22ea85ab721d8f6e8d99
ToppCellASK454-Epithelial-Type_2|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CFTR SPAG16

2.99e-0412972f8ea75314b9fa2bdc57564cad9640893a47f0340
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HEMGN ZNF711 RHEX ZFHX2

3.15e-04149974e99b7cd3728ce76b365526734c2e7f845b2e62c8
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-hematopoietic_progenitor|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HEMGN ZNF711 RHEX ZFHX2

3.15e-041499746a28dd4530ed411747fdfe743db138a1b5547ed7
ToppCell368C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

KIF27 IDO1 TRANK1 LRRC7

3.23e-04150974c3ad5fa41eb636a5d691c0268c0f1c32cd0de658
ToppCell368C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

KIF27 IDO1 TRANK1 LRRC7

3.23e-0415097478b8029e71d26f336a46274c8afef3435bf536b9
ToppCellnormal_Lung-Myeloid_cells-Undetermined|normal_Lung / Location, Cell class and cell subclass

ZNF384 IDO1 CALHM6 PMFBP1

3.32e-0415197423b6cf9a36ad0e937f69c75921bddd305a9a526c
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SMARCAD1 ZBTB39 PPP1R16B LRRC7

3.40e-04152974669d8f12fdb110ed72f4e5348b7b5350144a061c
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_memory_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SALL2 SUPV3L1 SMARCA2 PPP1R16B

3.48e-0415397464d0f37d7af9b76234f683379e3689771f71fe70
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRRK2 C16orf96 GREB1L RHEX

3.48e-04153974d6526d17826470534b766df144c74e73eb83fdad
ToppCellCOVID-19_Mild-Neu_0|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

ZNF280B TRIM69 WIZ

3.51e-04639731ab77b6f098686bc168427159282bbf3538d4292
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE SYNE1 KIF15 HSD11B1

3.57e-0415497471ffc23a2e02e27cabbdbeaa622e59e9f4a4cd9d
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SMARCAD1 ZNF236 OSGEPL1 CFAP97

3.57e-04154974ec920cae12ea1d14b6c973f6e903f895f80e3c50
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Matrix_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

FLT1 TSGA13 TRIM69 PPP1R16B

3.57e-04154974928f49839b046b90c2f942458f3e365ddc4e0bc9
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE SYNE1 KIF15 HSD11B1

3.57e-0415497446155f36d3983f637b55d7525b675c8828f6ab2e
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IDO1 PON2 ZNF711 RHEX

3.66e-04155974fab281db4c275d51240b122be78713c839ba5a95
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF804A TBX18 ZBTB39 SPHKAP

3.66e-041559748fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellfacs-Lung-EPCAM-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 ZBTB9 SPHKAP PPP1R16B

3.66e-041559740e942609d3e060f1e589fee5997fc6299f3d18bc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 WT1 ZBTB9 RHEX

3.75e-04156974dd41ed918b07fa248da458a629b3c53cb7ea8764
ComputationalNeighborhood of NF2

DENND4A RETREG2 WDR33 KIAA2013 SAFB BOD1L1 COG5 HECTD1

7.87e-05302518GCM_NF2
Diseasefatty acid measurement, linoleic acid measurement

KIF27 COBLL1 HMGCR SMARCA4

6.45e-0568934EFO_0005110, EFO_0006807
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

SMARCA2 SMARCA4

9.77e-055932C3281201
Diseaseopportunistic bacterial infectious disease (implicated_via_orthology)

SMARCA2 SMARCA4

3.49e-049932DOID:0050340 (implicated_via_orthology)
DiseaseDrug habituation

SYNE1 CFTR FHOD3 ZNF804A

4.89e-04115934C0013170
DiseaseDrug abuse

SYNE1 CFTR FHOD3 ZNF804A

4.89e-04115934C0013146
DiseasePrescription Drug Abuse

SYNE1 CFTR FHOD3 ZNF804A

4.89e-04115934C4316881
DiseaseSubstance-Related Disorders

SYNE1 CFTR FHOD3 ZNF804A

4.89e-04115934C0236969
DiseaseDrug Use Disorders

SYNE1 CFTR FHOD3 ZNF804A

4.89e-04115934C0013222
DiseaseDrug Dependence

SYNE1 CFTR FHOD3 ZNF804A

4.89e-04115934C1510472
DiseaseSubstance Dependence

SYNE1 CFTR FHOD3 ZNF804A

4.89e-04115934C0038580
DiseaseSubstance Use Disorders

SYNE1 CFTR FHOD3 ZNF804A

4.89e-04115934C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

SYNE1 CFTR FHOD3 ZNF804A

4.89e-04115934C0029231
DiseaseSubstance abuse problem

SYNE1 CFTR FHOD3 ZNF804A

5.06e-04116934C0740858
Diseasephospholipids in very small VLDL measurement

HMGCR SMARCA4 PMFBP1

5.66e-0451933EFO_0022300
Diseasetriglycerides to total lipids in very large VLDL percentage

COBLL1 HMGCR SMARCA4

6.33e-0453933EFO_0022340
Diseasecholesteryl esters to total lipids in large VLDL percentage

COBLL1 HMGCR SMARCA4

7.44e-0456933EFO_0022250
DiseaseCoffin-Siris syndrome

SMARCA2 SMARCA4

7.49e-0413932C0265338
DiseaseMental Retardation, X-Linked Nonsyndromic

ZNF711 PTCHD1

7.49e-0413932C3501611
DiseaseHyperlipoproteinemia Type IIb

PON2 HMGCR

7.49e-0413932C1704417
Diseasefree cholesterol to total lipids in medium VLDL percentage

COBLL1 HMGCR SMARCA4

7.84e-0457933EFO_0022284
Diseasetriglycerides to total lipids in medium VLDL percentage

COBLL1 HMGCR SMARCA4

1.05e-0363933EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

COBLL1 HMGCR SMARCA4

1.05e-0363933EFO_0022239
DiseaseHyperlipoproteinemia Type IIa

PON2 HMGCR

1.15e-0316932C0745103
DiseaseLeber congenital amaurosis

SPATA7 CEP290

1.15e-0316932cv:C0339527
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

FLT1 LRRK2 ZNF804A DCLK3

1.26e-03148934C0279702
Diseasecoronary artery disease

FLT1 WDR33 CFTR WT1 HEMGN HMGCR SMARCA4 LRRC7 COG5 ADGRL3 PMFBP1

1.33e-0311949311EFO_0001645
DiseaseHypercholesterolemia, Familial

PON2 HMGCR

1.45e-0318932C0020445
Diseasenephrotic syndrome

ZNF438 CALHM6 CCDC66

1.48e-0371933EFO_0004255
Diseasefree cholesterol to total lipids in small VLDL percentage

COBLL1 HMGCR SMARCA4

1.74e-0375933EFO_0022287
Diseasevital capacity

ZNF438 FLT1 ERC1 SYNE1 WT1 C16orf96 TBX18 SMARCA2 PLAG1 PIBF1 PMFBP1

1.75e-0312369311EFO_0004312
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

KIF27 COBLL1 PON2 SMARCA4 PMFBP1

1.84e-03276935EFO_0004612, EFO_0020943
Diseasenon-high density lipoprotein cholesterol measurement

SP1 PDE3B COBLL1 HMGCR SMARCA4 ASCC3 COG5 PMFBP1

1.87e-03713938EFO_0005689
DiseaseMalignant neoplasm of breast

ZNF438 FLT1 IDO1 SYNE1 WT1 ANKRD30A BOD1L1 LRRC7 HSD11B1 KAT6B

2.06e-0310749310C0006142
DiseaseLeber Congenital Amaurosis

SPATA7 CEP290

2.18e-0322932C0339527
Diseasefree cholesterol:total lipids ratio, intermediate density lipoprotein measurement

COBLL1 HMGCR SMARCA4

2.57e-0386933EFO_0008595, EFO_0020945
Diseaseunipolar depression, schizophrenia

ZNF804A PPP1R16B

2.81e-0325932EFO_0003761, MONDO_0005090
Diseasepre-eclampsia (is_implicated_in)

FLT1 HSD11B1

2.81e-0325932DOID:10591 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
LKNVKFMNHVKHHLE

ZNF280B

316

Q86YH2
LLATKNSHLRHIEHM

RNF40

416

O75150
LDHRHKQKVLHDTMD

CFAP97

331

Q9P2B7
LITVSKILHHKMLHS

CFTR

941

P13569
VLMAHVEVKHSDAVH

ADGRL3

846

Q9HAR2
AREHLELLKHMHTVG

APTX

231

Q7Z2E3
TIDIHFLERKMQHHL

ANKRD30A

1351

Q9BXX3
EDHLAVHKHKHEMTL

ATF7

21

P17544
LNLFHDDIHHVRKSM

HSD11B1

126

P28845
KDDQDMHALGKKHTH

COBLL1

756

Q53SF7
MHALGKKHTHENVKE

COBLL1

761

Q53SF7
HVLPIEKHISHFMHK

DENND4A

341

Q7Z401
MHVHHLESLLEQKEK

ERC1

341

Q8IUD2
LQMAELVTTHKCLHH

RABEP2

361

Q9H5N1
HDIATTLQHLHMIDK

KAT6B

936

Q8WYB5
HHMEAHALTIRLTNK

OSGEPL1

146

Q9H4B0
KLNMLSIDHLTDHKS

IDO1

61

P14902
HVDKLEHHSTQMQEL

KIF15

746

Q9NS87
DMVHLVHARKAQHLA

NRAP

876

Q86VF7
HSFVHMEHEKAVLLL

LRRC7

1506

Q96NW7
HLVKSHMIHNRSKIN

HMGCR

861

P04035
MVKLDIHTLAHHLKQ

GAPVD1

1

Q14C86
LCKALVHMHDKSIVH

DCLK3

461

Q9C098
KEHEQKMQLLLHHFK

KIF27

1171

Q86VH2
LMHHLTENHKIWKEI

PDE3B

1061

Q13370
HHEMKETNEQKLHKI

FGD4

196

Q96M96
IHLNVLELMQKHIHS

LRRK2

441

Q5S007
MHKLHFLHSDLALRN

LMTK2

256

Q8IWU2
HAMEGISHLHLLVVK

GREB1L

1536

Q9C091
MDLGKDQSHLKHHQT

HEMGN

1

Q9BXL5
HKHDVIMKSQLRHKS

PPP1R16B

316

Q96T49
AHEIHVLEKHTNMNL

PON2

241

Q15165
HADHRSTLTKKMHIQ

BOD1L1

1196

Q8NFC6
KLHQSVTKAIHALME

COG5

586

Q9UP83
HLVHKDTLHSAMAVV

HECTD1

156

Q9ULT8
HGILEHIHMAELKKV

C16orf96

31

A6NNT2
MEKFRAVLDLHVKHH

CALHM6

1

Q5R3K3
EMEPKSHHTLKIAHQ

CEP290

1526

O15078
HMTLKERHGELQDHK

CEP250

1851

Q9BV73
HKQSLLHHVCTMVVE

FHOD3

1121

Q2V2M9
HKKHITAENMKSSLV

CCDC66

136

A2RUB6
EFMRSDHLKQHQKTH

KLF17

351

Q5JT82
HLHVKFAALMQHQAK

DBR1

226

Q9UK59
ILKAHMVTHSSRKDH

E4F1

206

Q66K89
ERATLKKHMLLAHHQ

SALL2

951

Q9Y467
EELKIVHMHLKEHQE

CENPE

1721

Q02224
VHMHLKEHQETIDKL

CENPE

1726

Q02224
EKDHLHSVMVHLQQE

PMFBP1

921

Q8TBY8
LRHSIDEVHHKNMII

SPHKAP

676

Q2M3C7
HMAHKSEQILKAASL

RHEX

36

Q6ZWK4
MRSDHLAKHVKTHQN

SP5

366

Q6BEB4
HAKEHSTMQKLHCTQ

PLCB4

946

Q15147
MKNHHCKLTQVLNTH

SMARCA2

856

P51531
MMLDILEVLLKHHQH

SMARCAD1

881

Q9H4L7
EILQDHHKQLMQIKH

SYNE1

8586

Q8NF91
HHKQLMQIKHELLES

SYNE1

8591

Q8NF91
LSHMQLHHLDPKTFK

LGI4

191

Q8N135
MLDQHHTDLILKLHA

PTCHD1

106

Q96NR3
LGHKRKVEIMHTHSL

NBEA

776

Q8NFP9
SMKAEANALHHKHDK

RETREG2

246

Q8NC44
MKNHHCKLTQVLNTH

SMARCA4

886

P51532
FKQKEHLLEHMSQHR

WIZ

276

O95785
HNITKLIKMSETHKL

SUPV3L1

671

Q8IYB8
MRSDHLSKHIKTHQN

SP1

696

P08047
HLHKTELHGKMISVE

SAFB

466

Q15424
LKDMRKDEIGHILHH

ASCC3

1151

Q8N3C0
DHLTRHMKKSHNQEL

PLAG1

226

Q6DJT9
AHKENKLHLQQHVSM

TRIM69

191

Q86WT6
SKELLLKVMESHHQH

TSGA13

121

Q96PP4
TDMNTHIHQVHKEKS

ZNF451

766

Q9Y4E5
HISLHRIVDKMHDSN

PLEK2

126

Q9NYT0
QHTRIHSKMHTETIK

ZNF384

301

Q8TF68
NLVEHKKMHTGEKSH

ZNF260

41

Q3ZCT1
NSVSHLHKMKKAAID

ZFHX2

1211

Q9C0A1
HLDVAIKTMNKVASH

TIAM1

1216

Q13009
FNKLKHHLMEQHNIE

RLF

1421

Q13129
ELDDQGHIILHSMHK

TBX18

251

O95935
MRSDHLAKHIKTHQN

SP3

691

Q02447
HEKHHTLLKEKMLTS

SPAG16

231

Q8N0X2
ILVKMHSKHSENSLL

PIBF1

691

Q8WXW3
KLSHLQMHSRKHTGE

WT1

336

P19544
TLKMEHHLEAHKNGH

SGMS1

66

Q86VZ5
HIKQNKHLEEEKMRH

SPATA7

396

Q9P0W8
KHLEEEKMRHLLHVL

SPATA7

401

Q9P0W8
HLLEKHMAVHQSLED

ZBTB39

521

O15060
KLKHHLTEHMKTHAG

ZBTB9

421

Q96C00
SKDLESHMIHHCKTR

ZNF507

681

Q8TCN5
KHQLKMHLLTHSSSQ

ZXDA

281

P98168
KRATHLKEHMQTHQA

ZNF236

1696

Q9UL36
HILLQHMKDTHKPGE

ZNF280C

396

Q8ND82
LEKHAESHMQQPKEH

ZNF407

201

Q9C0G0
LATLHAHKNTVMEVK

WDR33

281

Q9C0J8
GSKEHSHMLQKVQEH

TRANK1

2826

O15050
MTELKILTHIGHHLN

FLT1

876

P17948
SEKNQHIMRHHKEAL

ZNF711

746

Q9Y462
HHILMHLTEKAQEVT

THRSP

121

Q92748
STHMKLHHGENRLKK

ZNF438

551

Q7Z4V0
QKHHQEEIIHKLAMQ

PXT1

71

Q8NFP0
KLCQHHHMEKTKESE

ZNF804A

601

Q7Z570
LHLKAILAHDEHMAQ

KIAA2013

571

Q8IYS2
METVKVLRHHHSKLL

NMNAT3

91

Q96T66