Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsynaptic receptor adaptor activity

SHANK2 SHANK3

5.85e-054632GO:0030160
GeneOntologyCellularComponentextracellular matrix of synaptic cleft

LAMA5 SPARCL1

2.59e-053622GO:0098965
DomainLamG

HSPG2 COL18A1 FAT2 LAMA5

1.35e-0544624SM00282
DomainLaminin_G

HSPG2 COL18A1 FAT2 LAMA5

4.08e-0558624IPR001791
DomainLY6_UPAR

LY6G6D CD177 CD59

5.13e-0522623PS00983
DomainConA-like_dom

HSPG2 COL18A1 FAT2 LAMA5 ADGRD2 HERC1

8.63e-05219626IPR013320
DomainDMAP_binding

DIP2B DIP2C

1.08e-045622PF06464
DomainEGF

NID2 HSPG2 FAT2 FCGBP LAMA5 SORL1

1.27e-04235626SM00181
DomainDMAP1-bd

DIP2B DIP2C

1.61e-046622IPR010506
DomainDMAP_binding

DIP2B DIP2C

1.61e-046622SM01137
DomainEGF-like_dom

NID2 HSPG2 FAT2 FCGBP LAMA5 SORL1

1.74e-04249626IPR000742
DomainLAM_G_DOMAIN

HSPG2 FAT2 LAMA5

2.71e-0438623PS50025
DomainLAMININ_IVA

HSPG2 LAMA5

3.00e-048622PS51115
DomainLaminin_B

HSPG2 LAMA5

3.00e-048622PF00052
DomainLamB

HSPG2 LAMA5

3.00e-048622SM00281
DomainLaminin_IV

HSPG2 LAMA5

3.00e-048622IPR000034
DomainLaminin_G_2

HSPG2 FAT2 LAMA5

3.15e-0440623PF02210
DomainFol_N

FCGBP SPARCL1

5.85e-0411622IPR003645
DomainFOLN

FCGBP SPARCL1

5.85e-0411622SM00274
DomainLdl_recept_b

NID2 SORL1

9.62e-0414622PF00058
DomainLDLRB

NID2 SORL1

9.62e-0414622PS51120
DomainLY

NID2 SORL1

1.11e-0315622SM00135
DomainLDLR_classB_rpt

NID2 SORL1

1.11e-0315622IPR000033
DomainSAM_1

SHANK2 SHANK3 ARAP1

1.50e-0368623PF00536
DomainEGF-like_CS

NID2 HSPG2 FAT2 LAMA5 SORL1

1.73e-03261625IPR013032
DomainGrowth_fac_rcpt_

NID2 HSPG2 LAMA5 PCSK4

1.79e-03156624IPR009030
DomainEGF_2

NID2 HSPG2 FAT2 LAMA5 SORL1

1.85e-03265625PS01186
DomainRCC1

FBXO24 HERC1

1.98e-0320622PF00415
DomainUPAR_LY6

CD177 CD59

1.98e-0320622PF00021
DomainRCC1_1

FBXO24 HERC1

2.19e-0321622PS00625
DomainRCC1_2

FBXO24 HERC1

2.19e-0321622PS00626
DomainRCC1_3

FBXO24 HERC1

2.19e-0321622PS50012
DomainReg_chr_condens

FBXO24 HERC1

2.40e-0322622IPR000408
DomainLY6_UPA_recep-like

CD177 CD59

2.40e-0322622IPR016054
Domain-

FBXO24 HERC1

2.40e-03226222.130.10.30
DomainRCC1/BLIP-II

FBXO24 HERC1

2.62e-0323622IPR009091
DomainSAM

SHANK2 SHANK3 ARAP1

3.13e-0388623SM00454
Domain-

USP49 BRPF1 RNF8 UBR3 KDM5D PIAS2

3.68e-034496263.30.40.10
DomainFHA

STARD9 RNF8

3.88e-0328622SM00240
DomainSAM_DOMAIN

SHANK2 SHANK3 ARAP1

3.88e-0395623PS50105
Domain-

HSPG2 FAT2 LAMA5

3.88e-03956232.60.120.200
DomainZnf_RING/FYVE/PHD

USP49 BRPF1 RNF8 UBR3 KDM5D PIAS2

4.10e-03459626IPR013083
DomainSAM

SHANK2 SHANK3 ARAP1

4.11e-0397623IPR001660
DomainAMP-binding

DIP2B DIP2C

4.44e-0330622PF00501
DomainAMP-dep_Synth/Lig

DIP2B DIP2C

4.44e-0330622IPR000873
DomainEGF_LAM_2

HSPG2 LAMA5

4.44e-0330622PS50027
DomainEGF_LAM_1

HSPG2 LAMA5

4.44e-0330622PS01248
DomainFHA

STARD9 RNF8

4.74e-0331622PF00498
DomainJMJC

HSPBAP1 KDM5D

5.04e-0332622PS51184
DomainJmjC_dom

HSPBAP1 KDM5D

5.04e-0332622IPR003347
Domain-

SHANK2 SHANK3 ARAP1

5.27e-031066231.10.150.50
DomainJmjC

HSPBAP1 KDM5D

5.36e-0333622SM00558
DomainLaminin_EGF

HSPG2 LAMA5

6.01e-0335622PF00053
DomainEGF_Lam

HSPG2 LAMA5

6.01e-0335622SM00180
DomainFHA_dom

STARD9 RNF8

6.35e-0336622IPR000253
Domain-

STARD9 RNF8

6.35e-03366222.60.200.20
DomainSAM/pointed

SHANK2 SHANK3 ARAP1

6.93e-03117623IPR013761
DomainLaminin_EGF

HSPG2 LAMA5

7.06e-0338622IPR002049
Domain-

NID2 SORL1

7.42e-03396222.120.10.30
DomainEGF_3

NID2 HSPG2 FAT2 SORL1

7.71e-03235624PS50026
DomainEGF_CA

NID2 HSPG2 FAT2

7.77e-03122623SM00179
DomainLDLR_class-A_CS

HSPG2 SORL1

7.80e-0340622IPR023415
PathwayREACTOME_LAMININ_INTERACTIONS

NID2 HSPG2 COL18A1 LAMA5

2.13e-0630444M27216
Pubmed

Membrane-type MMPs are indispensable for placental labyrinth formation and development.

NID2 HSPG2 COL18A1 LAMA5

9.65e-091463420858856
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

NID2 HSPG2 COL18A1 LAMA5

2.24e-072963422613833
Pubmed

Loss of nidogen-1 and -2 results in syndactyly and changes in limb development.

NID2 HSPG2 COL18A1

9.25e-071163317023412
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

NID2 HSPG2 COL18A1 LAMA5

2.11e-065063423658023
Pubmed

Basement membrane composition in the early mouse embryo day 7.

NID2 HSPG2 LAMA5

2.54e-061563315895400
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

CHL1 RHCG NID2 HSPG2 COL18A1 FCGBP RNH1 CD177 CD59 LAMA5 DCXR

3.16e-061070631123533145
Pubmed

Characterization of the Shank family of synaptic proteins. Multiple genes, alternative splicing, and differential expression in brain and development.

SHANK2 SHANK3

3.23e-06263210506216
Pubmed

RNF8-dependent and RNF8-independent regulation of 53BP1 in response to DNA damage.

RNF8 TP53BP1

3.23e-06263218337245
Pubmed

Differentially altered social dominance- and cooperative-like behaviors in Shank2- and Shank3-mutant mice.

SHANK2 SHANK3

3.23e-06263233126897
Pubmed

Deletion of the basement membrane heparan sulfate proteoglycan type XVIII collagen causes hypertriglyceridemia in mice and humans.

HSPG2 COL18A1

3.23e-06263221085708
Pubmed

Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney.

HSPG2 COL18A1

3.23e-06263212514129
Pubmed

The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair.

KIF18B TP53BP1

3.23e-06263234192545
Pubmed

RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids.

RNF8 TP53BP1

3.23e-06263223249736
Pubmed

Expression profiles of the autism-related SHANK proteins in the human brain.

SHANK2 SHANK3

3.23e-06263237953224
Pubmed

Shank2/3 double knockout-based screening of cortical subregions links the retrosplenial area to the loss of social memory in autism spectrum disorders.

SHANK2 SHANK3

3.23e-06263236100669
Pubmed

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2.

SHANK2 SHANK3

3.23e-06263222699619
Pubmed

Proline-rich synapse-associated protein-1 and 2 (ProSAP1/Shank2 and ProSAP2/Shank3)-scaffolding proteins are also present in postsynaptic specializations of the peripheral nervous system.

SHANK2 SHANK3

3.23e-06263220800661
Pubmed

Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model.

SHANK2 SHANK3

3.23e-06263231052177
Pubmed

Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8.

RNF8 TP53BP1

3.23e-06263220385748
Pubmed

Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus.

SHANK2 SHANK3

3.23e-06263227199660
Pubmed

SHANK3 in vagal sensory neurons regulates body temperature, systemic inflammation, and sepsis.

SHANK2 SHANK3

3.23e-06263236845137
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

NID2 HSPG2 COL18A1 LAMA5 SPARCL1

7.03e-0614663527068509
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

CHL1 MST1 HSPG2 FAT2 FCGBP SPARCL1

7.33e-0625763616335952
Pubmed

Regulation of 53BP1 protein stability by RNF8 and RNF168 is important for efficient DNA double-strand break repair.

RNF8 TP53BP1

9.68e-06363225337968
Pubmed

The Shank family of scaffold proteins.

SHANK2 SHANK3

9.68e-06363210806096
Pubmed

Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis.

RNF8 TP53BP1

9.68e-06363218504301
Pubmed

Translational neurobiology in Shank mutant mice--model systems for neuropsychiatric disorders.

SHANK2 SHANK3

9.68e-06363225917711
Pubmed

Genetic dissection of susceptibility to audiogenic seizures in inbred mice.

TYR DOCK7

9.68e-0636322052619
Pubmed

CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1.

DIP2B DIP2C

9.68e-06363217236128
Pubmed

Modeling autism by SHANK gene mutations in mice.

SHANK2 SHANK3

9.68e-06363223583105
Pubmed

The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination.

RNF8 TP53BP1

9.68e-06363220080757
Pubmed

Heterogeneity of Cell Surface Glutamate and GABA Receptor Expression in Shank and CNTN4 Autism Mouse Models.

SHANK2 SHANK3

9.68e-06363229970989
Pubmed

S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis.

SHANK2 SHANK3

9.68e-06363234741005
Pubmed

Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events.

RNF8 TP53BP1

9.68e-06363221412056
Pubmed

Dynamic Change of Shanks Gene mRNA Expression and DNA Methylation in Epileptic Rat Model and Human Patients.

SHANK2 SHANK3

9.68e-06363232564287
Pubmed

Functional proteomics mapping of a human signaling pathway.

NID2 HSPG2 ARFGEF2 CD59 LAMA5 SPARCL1 HERC1 PIAS2

1.13e-0559163815231748
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

NID2 HSPG2 COL18A1 LAMA5

1.33e-057963418757743
Pubmed

Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.

DIP2B DIP2C SHANK3

1.80e-052863331600191
Pubmed

The collagen type XVIII endostatin domain is co-localized with perlecan in basement membranes in vivo.

HSPG2 COL18A1

1.93e-05463212588956
Pubmed

SHANK3 gene mutations associated with autism facilitate ligand binding to the Shank3 ankyrin repeat region.

SHANK2 SHANK3

1.93e-05463223897824
Pubmed

Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage.

RNF8 TP53BP1

1.93e-05463219124460
Pubmed

PTIP regulates 53BP1 and SMC1 at the DNA damage sites.

RNF8 TP53BP1

1.93e-05463219414588
Pubmed

Lack of association between NLGN3, NLGN4, SHANK2 and SHANK3 gene variants and autism spectrum disorder in a Chinese population.

SHANK2 SHANK3

1.93e-05463223468870
Pubmed

A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses.

RNF8 TP53BP1

1.93e-05463220075863
Pubmed

RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1.

RNF8 TP53BP1

1.93e-05463222865450
Pubmed

Subendothelial heparan sulfate proteoglycans become major L-selectin and monocyte chemoattractant protein-1 ligands upon renal ischemia/reperfusion.

HSPG2 COL18A1

1.93e-05463217525255
Pubmed

The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42.

SHANK2 SHANK3

1.93e-05463212626503
Pubmed

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly.

HSPG2 COL18A1 CD59 LAMA5

2.53e-059363438245532
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

HECTD4 UBR3 HERC1 PIAS2

2.75e-059563429643511
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HSPG2 SHANK2 HECTD4 ARFGEF2 DIP2C LAMA5 HERC1 ESPL1 ADCY9 ARAP1

2.79e-051105631035748872
Pubmed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

NID2 HSPG2 COL18A1 LAMA5

2.98e-059763427559042
Pubmed

Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor.

SHANK2 SHANK3

3.22e-05563216606358
Pubmed

Characterization of human RhCG and mouse Rhcg as novel nonerythroid Rh glycoprotein homologues predominantly expressed in kidney and testis.

RHCG TYR

3.22e-05563210852913
Pubmed

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.

DIP2B LAMA5

3.22e-05563220972440
Pubmed

The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42.

SHANK2 SHANK3

3.22e-05563212504591
Pubmed

Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens.

NID2 HSPG2

3.22e-05563212243745
Pubmed

Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan.

NID2 HSPG2

3.22e-05563211493006
Pubmed

Model-based prediction of human hair color using DNA variants.

TYR EXOC2

3.22e-05563221197618
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

NID2 HSPG2 COL18A1 LAMA5

3.50e-0510163420551380
Pubmed

Organization, evolution and functions of the human and mouse Ly6/uPAR family genes.

LY6G6D CD177 CD59

4.57e-053863327098205
Pubmed

A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction.

NID2 LAMA5

4.82e-05663218817539
Pubmed

Genetic mouse models of autism spectrum disorder present subtle heterogenous cardiac abnormalities.

SHANK3 VPS13B

4.82e-05663235445787
Pubmed

The proximity ligation assay reveals that at DNA double-strand breaks WRAP53β associates with γH2AX and controls interactions between RNF8 and MDC1.

RNF8 TP53BP1

4.82e-05663226734725
Pubmed

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.

RNF8 TP53BP1

4.82e-05663218001824
Pubmed

The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.

NID2 HSPG2

4.82e-05663211956183
Pubmed

Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly.

HSPG2 LAMA5

4.82e-05663215668394
Pubmed

Nidogen-2: a new basement membrane protein with diverse binding properties.

NID2 HSPG2

4.82e-0566329733643
Pubmed

Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins.

NID2 HSPG2

4.82e-05663210544250
Pubmed

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly.

RNF8 TP53BP1

6.74e-05763218001825
Pubmed

An Analysis of Translocations in the Mouse.

TYR DOCK7

6.74e-05763217247190
Pubmed

A comparative analysis of the fibulin protein family. Biochemical characterization, binding interactions, and tissue localization.

NID2 COL18A1

6.74e-05763217324935
Pubmed

Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells.

SHANK2 SHANK3

6.74e-05763215207857
Pubmed

Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin.

HSPG2 COL18A1

6.74e-05763237174615
Pubmed

Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family.

SHANK2 SHANK3

6.74e-05763210527873
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

RHCG HSPG2 COL18A1 FCGBP RNH1 CD59 LAMA5 DCXR SORL1

8.60e-05101663919056867
Pubmed

Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development.

NID2 HSPG2

8.98e-05863212015298
Pubmed

The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family.

SHANK2 SHANK3

8.98e-05863210958799
Pubmed

The leucine-rich repeat protein PRELP binds perlecan and collagens and may function as a basement membrane anchor.

NID2 HSPG2

8.98e-05863211847210
Pubmed

Dual role of laminin‑511 in regulating melanocyte migration and differentiation.

TYR LAMA5

8.98e-05863230273664
Pubmed

Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment.

COL18A1 LAMA5

8.98e-05863219651211
Pubmed

Sex Hormones Regulate SHANK Expression.

SHANK2 SHANK3

8.98e-05863230319350
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

NID2 HSPG2 COL18A1 LAMA5

1.08e-0413563428675934
Pubmed

ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking.

TP53BP1 ARAP1

1.15e-04963221275903
Pubmed

Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners.

NID2 HSPG2

1.15e-04963222952693
Pubmed

Perlecan maintains microvessel integrity in vivo and modulates their formation in vitro.

HSPG2 COL18A1

1.15e-04963223320101
Pubmed

Laminin γ1 C-terminal Glu to Gln mutation induces early postimplantation lethality.

HSPG2 LAMA5

1.15e-04963230456378
Pubmed

BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.

RNF8 TP53BP1

1.15e-04963230704900
Pubmed

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.

RNF8 TP53BP1

1.15e-04963220016603
Pubmed

The chromosomal distribution of mouse odorant receptor genes.

TYR OR8B2 OR8B3

1.32e-04546338570653
Pubmed

Generation of a conditionally null allele of the laminin alpha1 gene.

HSPG2 LAMA5

1.44e-041063216100707
Pubmed

Replication study of candidate genes for cognitive abilities: the Lothian Birth Cohort 1936.

SHANK3 SORL1

1.44e-041063219077115
Pubmed

Genetic determinants of hair, eye and skin pigmentation in Europeans.

TYR EXOC2

1.44e-041063217952075
Pubmed

Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo.

HSPG2 LAMA5

1.44e-041063216554364
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NID2 ZFHX4 RNH1 BRPF1 KIF18B TSSK4 ADCY9 UNC80 SORL1

1.74e-04111663931753913
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

MST1 HSPG2 COL18A1 LAMA5

1.75e-0415363425037231
Pubmed

Extracellular matrix protein composition dynamically changes during murine forelimb development.

NID2 HSPG2

1.76e-041163238303699
Pubmed

Two new cataract loci, Ccw and To3, and further mapping of the Npp and Opj cataracts in the mouse.

TYR DOCK7

1.76e-04116328812411
Pubmed

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair.

RNF8 TP53BP1

1.76e-041163220081839
Pubmed

Genome-wide association study of tanning phenotype in a population of European ancestry.

TYR EXOC2

1.76e-041163219340012
Pubmed

Behavioral phenotypes of genetic mouse models of autism.

SHANK2 SHANK3

1.76e-041163226403076
InteractionFGF4 interactions

NID2 HSPG2 COL18A1 LAMA5

7.69e-0644584int:FGF4
Cytoband9q33.3

WDR38 ADGRD2

1.20e-03376329q33.3
GeneFamilyCD molecules|Complement system|LY6/PLAUR domain containing

LY6G6D CD177 CD59

9.31e-05344731226
GeneFamilySterile alpha motif domain containing

SHANK2 SHANK3 ARAP1

1.55e-0388473760
CoexpressionNABA_BASEMENT_MEMBRANES

NID2 HSPG2 COL18A1 LAMA5

2.28e-0640614M5887
ToppCell3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 COL18A1 CD59 LAMA5 SPARCL1 SHANK3

2.74e-07188636be3d287ca60ec9b42be1a8eb0a9b911c16cd8c3a
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TYMS HSPG2 SPARCL1 KIF18B ESPL1 SHANK3

3.50e-07196636eb8c9a4a5eb21d43ff7b25deae5896c236f669b9
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|Epithelial / Condition, Lineage and Cell class

CHL1 FAT2 FCGBP SCNN1G SPARCL1 SORL1

3.60e-0719763678ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

DIP2B SHANK2 DIP2C UBR3 HERC1 VPS13B

3.82e-0719963694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellnormal_Lung-Endothelial_cells-Tumor_ECs|Endothelial_cells / Location, Cell class and cell subclass

TYMS HSPG2 RPL32 DZIP1L SPARCL1

2.64e-06154635afdc385397c7b13c9348eeef95f109f2363057ae
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RHCG RPL32 FCGBP KCNH1 DCXR

5.06e-0617663537a73c1980db2a2b2da67742bf05f6a5cf936bbe
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHL1 WDR38 NID2 HSPG2 COL18A1

5.65e-06180635b294f9db1e2ff51c94cde64fae4c2b057c0030a1
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 CD59 LAMA5 SPARCL1 SHANK3

6.12e-06183635a644258ba90acc62d571623e429d72ffc4b69203
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 CD59 LAMA5 SPARCL1 SHANK3

7.34e-06190635141266bf411ea675fbf889b20c1b08673c45ff95
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 CD59 LAMA5 SPARCL1 SHANK3

8.54e-06196635c5fe470f11ee4962bcfb30cddfd8c078af5b1222
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 COL18A1 CD59 SPARCL1 SHANK3

8.54e-06196635d5d3028fcbfa251a206d17ec33b3b313968f9d79
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

CHL1 STARD9 LAMA5 SPARCL1 SHANK3

8.54e-061966354ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 CD59 LAMA5 SPARCL1 SHANK3

8.75e-06197635e8e879b7634a29569061d3515d180784094a31e7
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TYMS HSPG2 SPARCL1 KIF18B SHANK3

8.75e-0619763576b61e60a757e58b465569538e632d6d9953e89a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 COL18A1 CD59 SHANK3

8.97e-061986357cddd474416651088a4e08edfc0ac420ff10a5fe
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CHL1 FAT2 PLEKHG7 SCNN1G LAMA5

8.97e-0619863519d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CHL1 FCGBP SHANK2 PLEKHG7 SCNN1G

8.97e-06198635fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 CD59 LAMA5 SPARCL1 SHANK3

9.19e-0619963507bda4ac8ffdce1a865ebc99e46c2a27925ff7a8
ToppCellcontrol-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CHL1 FAT2 SPARCL1 DCXR SORL1

9.19e-061996353d01f90ffd271ca00129192787e4921bdca7e01e
ToppCellBiopsy_Control_(H.)-Epithelial-MUC5AC+_High|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CHL1 FAT2 FCGBP CD177 SCNN1G

9.19e-06199635a5240868cea40574ed4ee45eb27a00c1812957ed
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 CD59 LAMA5 SPARCL1 SHANK3

9.41e-06200635cd3c638961144a2fc91c437a173cc37c7452fa74
ToppCell5'-Adult-SmallIntestine-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 CD59 LAMA5 SPARCL1 SHANK3

9.41e-062006352554b77edfe3d378296b0b25625caacbfb1c0e76
ToppCell3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 CD59 LAMA5 SPARCL1 SHANK3

9.41e-06200635074b5766c61fa8e61d0b1b76688ea0d1ec401e5b
ToppCellLPS-IL1RA-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TYMS MST1 SHANK2 AJUBA

3.17e-051276346b24630978eb0772b4cd3bf59e5bc4390be47619
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_A|TCGA-Thymus / Sample_Type by Project: Shred V9

MST1 COL18A1 RNH1 CD59

5.04e-051436342d77eaa8b4d8d2cec3f3e52d73502b3e2150f925
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TYR ZFHX4 MOV10L1 UNC80

7.79e-05160634c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

HSPG2 SCNN1G LAMA5 ADGRD2

7.79e-0516063458ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TYR ZFHX4 MOV10L1 UNC80

7.79e-0516063425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell10x5'-Liver-Hematopoietic_progenitors|Liver / Manually curated celltypes from each tissue

TYMS DZIP1L KIF18B ESPL1

8.98e-05166634ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Liver / Manually curated celltypes from each tissue

TYMS DZIP1L KIF18B ESPL1

8.98e-05166634a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

CHL1 STARD9 SPARCL1 SHANK3

9.20e-051676345af9127bae05768a5164d5708a4ad37edca99324
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHL1 WDR38 COL18A1 CD59

9.41e-0516863495dc690c1987b05685d36e6bb20eb79308696e30
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TYMS MST1 COL18A1 ESPL1

1.01e-04171634621f9da0bfa09c86fc89fd26919403e94cd56d2b
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CHL1 NID2 COL18A1 UNC80

1.03e-041726348d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCellNS-critical-d_0-4-Epithelial-FOXN4+|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TYMS HSPG2 DIP2C PCSK4

1.03e-04172634a00bb44d33658cb3a98accd6b60f3ce964c425b4
ToppCellmetastatic_Brain-Myeloid_cells-CD207+CD1a+_LCs|Myeloid_cells / Location, Cell class and cell subclass

CHL1 FCGBP SCNN1G UNC80

1.03e-0417263438d17e769fe8eac8b57b820490d4ddd969243ee7
ToppCellEndothelial-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 COL18A1 SPARCL1 SHANK3

1.03e-04172634a3201773a25832e92dd113fad165f1ecd37f5e91
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CHL1 FAT2 FCGBP SCNN1G

1.05e-04173634d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CHL1 HSPG2 COL18A1 SPARCL1

1.13e-04176634bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCell356C-Endothelial_cells-Endothelial-D|356C / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 CD59 SPARCL1 SHANK3

1.15e-04177634a0b172f40e0df97a288a5549ae7066697ad469b3
ToppCell3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCNH1 MOV10L1 SCNN1G SORL1

1.15e-041776346d89042bda8e244babb68929e84b25edcb545a77
ToppCell3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCNH1 MOV10L1 SCNN1G SORL1

1.15e-04177634daaccf1249dcf816df4caca695a944f53078291a
ToppCell3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCNH1 MOV10L1 SCNN1G SORL1

1.15e-04177634338bdda26796bf4e16072878c070212d1006cf57
ToppCell356C-Endothelial_cells-Endothelial-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 CD59 SPARCL1 SHANK3

1.15e-04177634ab8f09e118e4df696b0b4d33f013da020bdbd351
ToppCell3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCNH1 MOV10L1 SCNN1G SORL1

1.15e-04177634c5a16f984c836dbf7d0faf061677844167ab612a
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD59 LAMA5 SPARCL1 SHANK3

1.18e-04178634360d7a987f91d6d721487a921824057ec31a7332
ToppCelldroplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 COL18A1 ZFHX4 TSSK4

1.18e-041786343e8aacb27ed1a3c3978e21dddddd0828f8000692
ToppCell10x5'-blood-Lymphocytic_NK-Cycling_NK|blood / Manually curated celltypes from each tissue

TYMS FBXO24 KIF18B TSSK4

1.20e-04179634c93711273055a999335ba8d0f6500e4549f46cec
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac|lymph-node_spleen / Manually curated celltypes from each tissue

TYMS DZIP1L KIF18B ESPL1

1.23e-041806344eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 NID2 ZFHX4 KCNH1

1.25e-041816340b1e7335648823b1d83bdfa878ccd44efe7bba9a
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHL1 WDR38 COL18A1 CD59

1.25e-04181634098dbb3e0ff531c9720a233123250c1e39a97d4c
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

HSPG2 COL18A1 SPARCL1 SHANK3

1.28e-04182634d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 RHCG COL18A1 SCNN1G

1.28e-04182634fe4fb213dc0ca482b0f94097fe1b0a51fc2690e2
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TYMS KIF18B ESPL1 DCXR

1.28e-04182634f549b986caebc5eb1b2d12f34fe33087e8324a31
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CHL1 HSPG2 ZFHX4 ESPL1

1.28e-04182634a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

FCGBP SHANK2 PLEKHG7 SCNN1G

1.28e-041826343f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellBasal|World / shred by cell class for mouse tongue

COL18A1 KCNH1 LAMA5 AJUBA

1.31e-04183634c6729a207526ff4aa48176207b9353176f631fea
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

FCGBP SHANK2 PLEKHG7 SCNN1G

1.31e-04183634940cbe298e9c53b5622af09264586ed823d3141f
ToppCellControl-T/NK_proliferative|Control / Disease group and Cell class

TYMS RNF8 KIF18B ESPL1

1.31e-0418363409c2b4e630f1c338f02c1242e3598e870d6b0a28
ToppCell(7)_Epithelial-H_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

FAT2 CD177 SCNN1G LAMA5

1.34e-041846341f76b37c265b519171b767a52d48f31f0cdc4a3c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 COL18A1 FCGBP CD59

1.36e-041856346da9a06e1514d5d5f47359a14637f02539846096
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 COL18A1 FCGBP CD59

1.36e-041856344a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCellEndothelial-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 COL18A1 SPARCL1 SHANK3

1.36e-04185634dee0b7ba2f338f0979d2306aedf52ac35a36b60c
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAT2 FCGBP LAMA5 DCXR

1.39e-0418663437b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 COL18A1 SPARCL1 SHANK3

1.39e-041866342e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 COL18A1 SPARCL1 SHANK3

1.39e-04186634c3449e54454009973818fc1101933c6f0168258c
ToppCellCOPD-Epithelial-ATI|COPD / Disease state, Lineage and Cell class

HSPG2 SHANK2 SCNN1G LAMA5

1.39e-04186634df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HSPG2 COL18A1 SPARCL1 SHANK3

1.39e-04186634a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCellCOVID-19_Mild-Neu_4|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

TYMS RNF8 EXOC2 ESPL1

1.42e-04187634714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALPK3 CD59 LAMA5 SPARCL1

1.42e-0418763437d8ee5c8bd6324749e5a2adef1d0482c75da80c
ToppCellAT1_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 COL18A1 SCNN1G LAMA5

1.42e-04187634f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCelldroplet-Pancreas-Exocrine-24m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 HSPG2 RTP3 SPARCL1

1.42e-04187634a178b1fed80a0bf83aedb6262493ee17374734b5
ToppCell3'-Adult-Appendix-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALPK3 CD59 LAMA5 SPARCL1

1.42e-04187634ec98d5e480b08854dfd0ba6b1dc6610455f90640
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-Cycling_NK|GI_small-bowel / Manually curated celltypes from each tissue

TYMS FCGBP KIF18B ESPL1

1.42e-04187634265c690c2921fd201361a0ec8bc4d2a996fbcaf4
ToppCelldroplet-Pancreas-Exocrine-24m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 HSPG2 RTP3 SPARCL1

1.42e-04187634e60cbccf5842f25123fd34b9475759b7424b32e9
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

CHL1 LAMA5 SPARCL1 SHANK3

1.42e-0418763454d7588172ac145ff5045ad9771636729ca3f0ca
ToppCellEndothelial-A-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 COL18A1 MOV10L1 SPARCL1

1.42e-04187634febe0b99a6a815ce687160a0e7af55228b1d5beb
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RHCG COL18A1 SCNN1G SORL1

1.42e-04187634b7689e7f6511920cd2beff27389555fddf685f61
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

HSPG2 COL18A1 SPARCL1 SHANK3

1.42e-04187634be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCelldroplet-Pancreas-Exocrine-24m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 HSPG2 RTP3 SPARCL1

1.42e-041876342b8eda2812be0be68a6f01aa4038925d3d5b1e65
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAT2 FCGBP LAMA5 DCXR

1.45e-041886348ffb5394f7b00ea483a5fe4df894d22fda935e5c
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHCG COL18A1 FCGBP SCNN1G

1.45e-04188634315ce1736e3a84a63a8d5dfa70d411b501cb2532
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 LAMA5 SPARCL1 SHANK3

1.45e-04188634a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAT2 FCGBP LAMA5 DCXR

1.45e-04188634137ed9958044fab7a13648affb469585d1c48cf6
ToppCellEndothelial-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 COL18A1 SPARCL1 SHANK3

1.45e-041886340824d567356d360fd8e78e840c30529c139f98a1
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

SHANK2 SCNN1G DIP2C LAMA5

1.48e-041896345a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CHL1 STARD9 SPARCL1 SHANK3

1.51e-041906340e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CHL1 LAMA5 SPARCL1 SHANK3

1.51e-041906340a351609a72fd638c84b2435782e312ee6a33aac
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Notum))|Striatum / BrainAtlas - Mouse McCarroll V32

RHCG KIF18B PCSK4

1.52e-047363350a8164d967f2706344adcdc1562dc08c9f16c8f
ToppCellfacs-SCAT-Fat-3m-Endothelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTP3 LAMA5 SPARCL1 SHANK3

1.54e-04191634a0018f88f7132477cc467ee15db029a585290595
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 CD59 SPARCL1 SHANK3

1.54e-04191634adb2e3efcad02889d8229325080da5e7830fd3ae
ToppCellfacs-Skin|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 FAT2 FCGBP AJUBA

1.54e-04191634ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CHL1 STARD9 SPARCL1 SHANK3

1.54e-04191634f229abf69a1217194f74b0502486907e07dba989
ToppCellBasal_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

COL18A1 FAT2 CD177 LAMA5

1.54e-04191634a98915bad9a4a61dd4cbca798914849b805f4a19
ToppCellfacs-SCAT-Fat-3m-Endothelial-endothelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTP3 LAMA5 SPARCL1 SHANK3

1.54e-041916346b9bbf4a63d4e9a8075bb06c2aa644fcf4ee88b8
ToppCellfacs-SCAT-Fat-3m-Endothelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTP3 LAMA5 SPARCL1 SHANK3

1.54e-0419163490f0c193dce267a4f1a9b2501f636dafd0a34cf7
ToppCell5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 LAMA5 SPARCL1 SHANK3

1.57e-04192634eafead22bba48ac5ee568faa8946c444445c1034
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TYMS KIF18B ESPL1 DCXR

1.57e-04192634849ac3c115e6f913e68ca050c308bc4c32cf662b
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

DIP2B SHANK2 DIP2C VPS13B

1.57e-04192634e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 STARD9 SPARCL1 SHANK3

1.57e-04192634c0e59e642b42c055cf73d029cf54d07d9b719359
ComputationalNeighborhood of RRM2

TYMS KIF18B ESPL1

3.13e-0440363GNF2_RRM2
ComputationalNeighborhood of CENPE

TYMS KIF18B ESPL1

3.37e-0441363GNF2_CENPE
ComputationalNeighborhood of HMMR

TYMS KIF18B ESPL1

5.06e-0447363GNF2_HMMR
ComputationalNeighborhood of MCM4

TYMS KIF18B ESPL1

7.20e-0453363GNF2_MCM4
ComputationalNeighborhood of CDC20

TYMS KIF18B ESPL1

8.47e-0456363GNF2_CDC20
ComputationalNeighborhood of CCNB2

TYMS KIF18B ESPL1

8.92e-0457363GNF2_CCNB2
ComputationalNeighborhood of CCNA2

TYMS KIF18B ESPL1

1.49e-0368363GNF2_CCNA2
ComputationalNeighborhood of PCNA

TYMS KIF18B ESPL1

1.49e-0368363GNF2_PCNA
DrugE)-11-hexadecenyl acetate

KCNH1 KDM5D

7.54e-062632CID005352788
Druggamma-L-glutaminyl-3,4-benzoquinone

TYMS TYR

7.54e-062632CID000193125
Drughyaluronan

TYMS HSPG2 COL18A1 RNH1 LAMA5 KDM5D VPS13B

8.07e-06263637CID000024759
Drug0179445-0000 [211246-22-9]; Down 200; 10uM; MCF7; HT_HG-U133A

SHANK2 HECTD4 DIP2C ESPL1 VPS13B ADCY9

1.23e-051856364755_DN
Drugob-B

TYMS RNH1 SCNN1G

1.34e-0517633CID003032840
DrugAC1L1C2F

TYMS NID2 HSPG2 COL18A1 LAMA5

1.35e-05110635CID000001711
DrugN-Ac-4-S-CAP

TYMS TYR

2.26e-053632CID000124470
Drug1-tetradecene

KCNH1 DCXR

4.51e-054632CID000014260
DiseaseMental Retardation, Psychosocial

CHL1 COL18A1 SHANK2 SHANK3

1.76e-04139594C0025363
DiseaseProfound Mental Retardation

CHL1 COL18A1 SHANK2 SHANK3

1.76e-04139594C0020796
DiseaseMental deficiency

CHL1 COL18A1 SHANK2 SHANK3

1.76e-04139594C0917816
DiseaseIschemic stroke, fibrinogen measurement

DIP2B HECTD4 SHANK3

1.85e-0455593EFO_0004623, HP_0002140
Diseasefibrinogen measurement, factor VII measurement

DIP2B HECTD4 SHANK3

2.17e-0458593EFO_0004619, EFO_0004623
DiseaseMalignant neoplasm of breast

TYMS MST1 NID2 KCNH1 ARFGEF2 DIP2C VPS13B TP53BP1 SORL1

2.65e-041074599C0006142
Diseasevenous thromboembolism, fibrinogen measurement

DIP2B HECTD4 SHANK3

3.32e-0467593EFO_0004286, EFO_0004623
Diseasehair color

CHL1 TYR KCNH1 HECTD4 EXOC2

3.96e-04311595EFO_0003924
Diseasesyndromic intellectual disability (implicated_via_orthology)

BRPF1 KDM5D

4.63e-0416592DOID:0050888 (implicated_via_orthology)
DiseaseManic

SHANK2 STARD9 SHANK3

5.19e-0478593C0338831
DiseaseFEV/FEC ratio

NID2 HSPG2 FCGBP DZIP1L EXOC2 HERC1 AJUBA ARAP1 SORL1

7.01e-041228599EFO_0004713
Diseasefreckles

TYR EXOC2

7.30e-0420592EFO_0003963
Diseaseatrial fibrillation

HSPG2 ZFHX4 ADGRD2 HERC1 SORL1

8.78e-04371595EFO_0000275
Diseasesunburn

TYR USP49 EXOC2

9.51e-0496593EFO_0003958
Diseasemean corpuscular hemoglobin concentration

TYMS USP49 HECTD4 ARFGEF2 EXOC2 VPS13B ADCY9 CAPN15

1.54e-031105598EFO_0004528
Diseaselongitudinal BMI measurement, response to amisulpride

KIF18B ADCY9

1.54e-0329592EFO_0005937, EFO_0010718

Protein segments in the cluster

PeptideGeneStartEntry
ACQALDSLYHTQCFV

AJUBA

351

Q96IF1
TCNHALYAICDVFTQ

ARFGEF2

1401

Q9Y6D5
SSHQCNAYCELLGLT

ALPK3

1811

Q96L96
LVASYTHFCSSDLCN

CD177

286

Q8N6Q3
LAVFCHSGHSLQCYN

CD59

16

P13987
SSINSCAHTVYALCI

OR2L2

151

Q8NH16
AGVYICTCRNLHQSN

HSPG2

1741

P98160
AYLHVQCDCTDSFNV

CAPN15

996

O75808
YLLHCQDCLSASVAQ

DZIP1L

96

Q8IYY4
YCCLLAHSISSQVSA

MOV10L1

1046

Q9BXT6
QGIYCCSAHTALDSA

CHL1

586

O00533
DVYTAACNSVIHRCA

HERC1

1436

Q15751
HSSAQFIDSYICQVC

KDM5D

306

Q9BY66
DNCNCDGYTNSIHTL

PCSK4

306

Q6UW60
SNCCYLERHTFLNIA

EXOC2

716

Q96KP1
LTQCCLHSDYCSQNT

FAT2

3941

Q9NYQ8
QSAASCHHAYIVLCI

COL18A1

1731

P39060
SQCSQRAVTNHSVYC

DCXR

136

Q7Z4W1
MLSHCQALSQACNYS

DIP2B

536

Q9P265
QSCANVRALTYCDLH

KCNH1

656

O95259
QYCDICTAANSNKAH

LAMA5

101

O15230
LTFCSANIINHYLCD

OR8B3

166

Q8NGG8
HCIHSQNCSATDLFY

HECTD4

2511

Q9Y4D8
SLDCHISQYATICQQ

KIF18B

361

Q86Y91
NHRQCSRHAFCTDYA

NID2

491

Q14112
TSHAVNCCYLNAAVS

HSPBAP1

316

Q96EW2
YCALSNGHACLENRS

CEFIP

781

Q711Q0
LCYHDFTQQTNCSAL

ESPL1

636

Q14674
ACNQSAVYLQHCFAT

DOCK7

1516

Q96N67
LCSNIHAYVSACQAA

FCGBP

1501

Q9Y6R7
ILCSNIHAYVSACQA

FCGBP

2701

Q9Y6R7
SILCSNIHAYVSACQ

FCGBP

3901

Q9Y6R7
ALLTHCQALTQACGY

DIP2C

516

Q9Y2E4
AALIAVVHYCNFCQL

ADCY9

901

O60503
AQACEEYLSQIHSCQ

FBXO24

516

O75426
CRAFHYNVSSHGCQL

MST1

66

P26927
CSVSQRYCNLNHFNA

SLC15A5

526

A6NIM6
NAAYSLQICLHSCFQ

SCNN1G

386

P51170
LTFCSANIINHYLCD

OR8B2

166

Q96RD0
TCTHLQCFDAALYLQ

PIAS2

361

O75928
CYLGDLCNSAVASHV

LY6G6D

96

O95868
YACQNHICRNLSIFC

RTP3

201

Q9BQQ7
NCTAIYHTCEASNFQ

SORL1

1191

Q92673
CNKSYCAEIAHNVSS

RPL32

91

P62910
IEAVTLNCAHSFCSY

RNF8

411

O76064
AACSDNLHNLFSCQA

STARD9

4501

Q9P2P6
HICALYNQDSCARVL

SHANK2

336

Q9UPX8
HKANCYTAFHVTCAQ

BRPF1

401

P55201
VAALYLDSTACFCNH

ADGRD2

621

Q7Z7M1
ISHLYCVQCFSDTNQ

ARAP1

1086

Q96P48
SQYHAIRAATMCNLC

ZFHX4

1371

Q86UP3
RQVNCFSHLSQTYCG

TSSK4

186

Q6SA08
LCNQQSFICTHVDYC

UNC80

1466

Q8N2C7
ALHICALYNQESCAR

SHANK3

286

Q9BYB0
VCGTDNQTYASSCHL

SPARCL1

471

Q14515
HGQLLSQVTCISCNY

USP49

446

Q70CQ1
CSRLEEYNSHQSLCN

TYR

276

P14679
HALCQFYVVNSELSC

TYMS

196

P04818
TAACCSHFSSVLAQN

RNH1

326

P13489
CNTAYQCLLIADQHC

TP53BP1

1796

Q12888
QHRAAINTYCSLAAC

RHCG

246

Q9UBD6
QALEGHSANISCLCY

WDR38

186

Q5JTN6
QSYCECVLHSQNCGA

UBR3

1796

Q6ZT12
DYCHNSGAVLLCSIQ

VPS13B

936

Q7Z7G8
CQSHQTYCLNYSAAI

PLEKHG7

386

Q6ZR37
SHRDCQANNICCSTY

WFDC10A

56

Q9H1F0