Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R33 TAS2R36 TAS2R20 TAS2R19

1.71e-05271164GO:0033038
GeneOntologyMolecularFunctiontaste receptor activity

TAS2R33 TAS2R36 TAS2R20 TAS2R19

3.88e-05331164GO:0008527
GeneOntologyMolecularFunctionmicrotubule binding

CENPE CENPF LRRK2 JAKMIP3 OPA1 DST CCSER2 MTCL1 CDK5

7.91e-053081169GO:0008017
GeneOntologyMolecularFunctionmyosin phosphatase regulator activity

PPP1R16B PPP1R16A

1.99e-0441162GO:0017020
GeneOntologyMolecularFunctioncentromeric DNA binding

CENPC MLH3

6.89e-0471162GO:0019237
GeneOntologyMolecularFunctionprotein kinase activity

NRBP1 PLK2 CAD LRRK2 MAP3K12 JAK2 NEK1 NEK5 MAPK7 PRKX CDK5

7.47e-0460011611GO:0004672
GeneOntologyMolecularFunctiontubulin binding

CENPE CENPF LRRK2 JAKMIP3 OPA1 DST CCSER2 MTCL1 CDK5

8.87e-044281169GO:0015631
MousePhenoabnormal skin appearance

PDS5B PLK2 ABCA12 SPTA1 MAEA NFKBIZ TSC1 JAK2 DST TMCC2 WDFY3 RAPGEF2 MAPK7 TPH1

2.09e-064739114MP:0009931
MousePhenopallor

PDS5B PLK2 SPTA1 MAEA TSC1 JAK2 TMCC2 WDFY3 MAPK7 TPH1

3.38e-062399110MP:0003717
DomainARM-like

PDS5B SETX LRRK2 HEATR1 ARMCX2 ECPAS ARID1A TRRAP LTN1 WDFY3 STAG3

5.66e-0727011011IPR011989
Domain-

PDS5B LRRK2 HEATR1 ARMCX2 ECPAS ARID1A TRRAP WDFY3 STAG3

6.61e-0622211091.25.10.10
DomainKinase-like_dom

NRBP1 PLK2 LRRK2 ARHGAP35 TRRAP MAP3K12 JAK2 NEK1 DST NEK5 MAPK7 PRKX CDK5

1.82e-0554211013IPR011009
DomainARM-type_fold

PDS5B LRRK2 HEATR1 ARMCX2 ECPAS ARID1A TRRAP LTN1 WDFY3 STAG3

3.20e-0533911010IPR016024
DomainPase-1_reg_su_16AB

PPP1R16B PPP1R16A

3.44e-0521102IPR017417
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

EDC3 SETX TBC1D30 CENPE CENPF MYO7A RPS9 LCA5L ZBTB41 ECPAS JAK2 FRY DST MTHFD1 ZNF408 MTCL1

3.82e-097361171629676528
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

NCOA2 EDC3 SETX NFKBIZ ZBTB41 HEATR1 ZBTB24 ZNF182 SEPSECS ALKBH8 GBP4 VPS33B MTHFD1 LTN1 CCSER2 AEBP2 PCNT

1.40e-0710841171711544199
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOA2 CAD CENPE CENPF TSC1 JAKMIP3 OPA1 FRY DST SEC23IP MTCL1 WDFY3 RAPGEF2 GOLGA4 CDK5 PCNT

1.56e-079631171628671696
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

SPTA1 RPS9 TRRAP TRAP1 DST MTHFD1 NINL PCNT

2.49e-07187117826460568
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PDS5B CENPC CENPF SPTA1 NMRAL1 TSC1 ZBTB41 HEATR1 CFAP210 ARID1A CCDC57 TRAP1 OR13D1 DST STXBP2 SEC23IP RPL3L MYBPC1 PCNT

3.50e-0714421171935575683
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PPFIBP1 ARHGAP35 ZBTB24 DST TMCC2 PPP1R16B WDFY3 PCNT

1.01e-06225117812168954
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

PDS5B CENPE CENPF MYO7A TSC1 ECPAS CCDC57 TRRAP OPA1 MTHFD1 ZNF408

1.01e-064971171136774506
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NCOA2 NRBP1 PLK2 PPFIBP1 ZNF521 JAKMIP3 ARID1A FRY DST ZNF92 SEC23IP DENND6B PPP1R16B LRRCC1 WDFY3 RAPGEF2 PCNT

1.47e-0612851171735914814
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

EDC3 PPFIBP1 ECPAS ARID1A DST VPS33B CCSER2 NINL MTCL1 RAPGEF2

2.86e-064461171024255178
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

PDS5B CAD CENPF RPS9 RTN3 RO60 HEATR1 ECPAS OPA1 TRAP1 VPS33B MTHFD1 SEC23IP TDRD6 CLUH GOLGA4 MYBPC1

5.83e-0614251171730948266
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TBC1D30 PPFIBP1 ARHGAP35 ARMCX2 NEK1 TMCC2 LTN1 LRRCC1 UBR3 MBD5

6.89e-064931171015368895
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NCOA2 MAEA RTN3 ARHGAP35 ECPAS ARID1A CCDC57 TRRAP LRRC8D MAP3K12 JAK2 FAM13A RAPGEF2 MBD5 PRKX GOLGA4 PCNT

1.03e-0514891171728611215
Pubmed

Identification of De Novo JAK2 and MAPK7 Mutations Related to Autism Spectrum Disorder Using Whole-Exome Sequencing in a Chinese Child and Adolescent Trio-Based Sample.

JAK2 MAPK7

1.12e-052117231838722
Pubmed

Identification of a novel GOLGA4-JAK2 fusion gene in B-cell acute lymphoblastic leukaemia.

JAK2 GOLGA4

1.12e-052117234697799
Pubmed

[Interferon-inducible genes 2', 5'-ollgoadenylate synthetase-like and tetratricopeptide repeats 2 are correlated with clinical features of patients with systemic lupus erythematosus].

IFIT2 OASL

1.12e-052117220506645
Pubmed

Parkinson-Related LRRK2 Mutation R1628P Enables Cdk5 Phosphorylation of LRRK2 and Upregulates Its Kinase Activity.

LRRK2 CDK5

1.12e-052117226930193
Pubmed

Comparison of munc-18 and cdk5 expression in the nervous system during mouse embryogenesis.

STXBP2 CDK5

1.12e-052117210579588
Pubmed

Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex.

RAPGEF2 CDK5

1.12e-052117225189171
Pubmed

Chromosomal localization of the genes encoding the kinetochore proteins CENPE and CENPF to human chromosomes 4q24-->q25 and 1q32-->q41, respectively, by fluorescence in situ hybridization.

CENPE CENPF

1.12e-05211727851898
Pubmed

Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells.

APTX OPA1

1.12e-052117230986824
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

PDS5B CAD SETX CENPC RPS9 TSC1 HEATR1 ARID1A TRRAP DST VPS33B MTHFD1 LTN1 TXNDC9 WDFY3 GOLGA4

1.26e-0513531171629467282
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

EDC3 SETX PPFIBP1 LRRK2 PKHD1L1 ARL6 DST MTHFD1 SEC23IP TXNDC9 RAPGEF2 GOLGA4

1.28e-057771171235844135
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PDS5B CAD CENPF HEATR1 ECPAS ARID1A TRRAP DST OASL CLUH PCNT

1.35e-056531171122586326
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MYO7A MAEA ARHGAP35 ARID1A TRRAP JAK2 DST ZNF408 TMCC2 NINL WDFY3 MBD5 PCNT PPP1R16A

2.16e-0511051171435748872
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

CENPF HEATR1 ARHGAP35 ECPAS ARID1A TRAP1 DST TXNDC9 GOLGA4

3.28e-05472117938943005
Pubmed

CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis.

MAPK7 CDK5

3.36e-053117227735944
Pubmed

LRRK2 Facilitates tau Phosphorylation through Strong Interaction with tau and cdk5.

LRRK2 CDK5

3.36e-053117226268594
Pubmed

Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1.

CENPE CENPF

3.36e-05311729763420
Pubmed

Loss of RTN3 phenocopies chronic kidney disease and results in activation of the IGF2-JAK2 pathway in proximal tubular epithelial cells.

RTN3 JAK2

3.36e-053117235596061
Pubmed

The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases.

CENPE CENPF

3.36e-053117229748388
Pubmed

The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth and chemosensitivity under hypoxic conditions.

PLK2 TSC1

3.36e-053117220054236
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

EDC3 MYO7A PPFIBP1 MAEA HEATR1 OPA1 ARL6 NEK1 TRAP1 SEPSECS NEK5 SEC23IP NINL CLUH CDK5

3.83e-0513211171527173435
Pubmed

Defining the membrane proteome of NK cells.

CAD EDC3 CENPE RPS9 HEATR1 ECPAS LRRC8D OPA1 TRAP1 MTHFD1 GLE1 OASL RPL3L PCNT

3.96e-0511681171419946888
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

CAD CENPE CENPF RTN3 TSC1 HEATR1 ARMCX2 OPA1 TRAP1 DST VPS33B SEC23IP TXNDC9 MCUB CLUH PCNT

4.24e-0514961171632877691
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

CAD IL1RAPL1 TRAP1 DST LRRCC1 TDRD6 PCNT

5.19e-05284117729459677
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

CENPF DST ZNF92 CCSER2 GOLGA4

5.54e-05120117531413325
Pubmed

Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules.

CENPE CENPF

6.70e-054117210852915
Pubmed

Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly.

MYO7A LRRC4C

6.70e-054117215590698
Pubmed

Expression of the NEK family in normal and cancer tissue: an immunohistochemical study.

NEK1 NEK5

6.70e-054117231906878
Pubmed

R-loops in proliferating cells but not in the brain: implications for AOA2 and other autosomal recessive ataxias.

SETX APTX

6.70e-054117224637776
Pubmed

Distribution of centromeric proteins and PARP-1 during mitosis and apoptosis.

CENPE CENPF

6.70e-054117219723035
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

EDC3 RPS9 TSC1 HEATR1 ARHGAP35 NEK1 TRAP1 DST MTHFD1 SEC23IP TXNDC9 PCNT

7.60e-059341171233916271
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

EDC3 PPFIBP1 ARHGAP35 NEK1 DST MTCL1

7.87e-05209117636779422
Pubmed

Mammalian centromeres: DNA sequence, protein composition, and role in cell cycle progression.

CENPC CENPE

1.11e-04511729925740
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

CAD EDC3 PPFIBP1 RPS9 ECPAS OPA1 DST MTHFD1 SEC23IP GOLGA4

1.45e-047081171039231216
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

EDC3 CENPE PPFIBP1 TSC1 ECPAS CCDC57 STXBP2 VPS33B NINL LRRCC1 PCNT

1.48e-048531171128718761
Pubmed

Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

CAD RPS9 RO60 HEATR1 ARID1A OPA1 DST MTHFD1

1.56e-04454117833226137
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PLK2 EDC3 SETX PPFIBP1 NEK1 DST FAM13A CCSER2 MTCL1 RAPGEF2 GOLGA4

1.61e-048611171136931259
Pubmed

The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon.

RPS9 LTN1

1.67e-046117225877867
Pubmed

Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype.

CENPE CENPF

1.67e-046117211084331
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

NCOA2 CAD SETX CENPE RTN3 TSC1 ARID1A ZNF92 PCNT

1.74e-04588117938580884
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

PDS5B CAD CENPF RPS9 HEATR1 TRRAP TRAP1 DST STXBP2 MTHFD1 GLE1 PCNT

1.79e-0410241171224711643
Pubmed

Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A.

CENPC CENPE

2.33e-047117211682612
Pubmed

Systematic discovery of nonobvious human disease models through orthologous phenotypes.

SEC23IP MAPK7

2.33e-047117220308572
Pubmed

Asymmetric distribution of prickle-like 2 reveals an early underlying polarization of vestibular sensory epithelia in the inner ear.

MYO7A PCNT

2.33e-047117217376975
Pubmed

The E3 ubiquitin ligase protein associated with Myc (Pam) regulates mammalian/mechanistic target of rapamycin complex 1 (mTORC1) signaling in vivo through N- and C-terminal domains.

TSC1 MAP3K12

2.33e-047117222798074
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

SETX RPS9 HEATR1 ARMCX2 OPA1 MTHFD1

2.69e-04262117636880596
Pubmed

Exploration of the cell-cycle genes found within the RIKEN FANTOM2 data set.

NEK1 NEK5

3.10e-048117212819135
Pubmed

Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13.

PDS5B FRY

3.10e-04811728812419
Pubmed

Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor γ (PPARγ) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes.

NCOA2 CDK5

3.10e-048117223178929
Pubmed

Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily.

LRRK2 OPA1

3.10e-048117224282027
Pubmed

Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico.

CAD COL16A1 ARID1A

3.10e-0439117325859222
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOA2 GALNT3 MYO7A ARID1A IL1RAPL1 LRR1 SEC23IP MTCL1 WDFY3

3.17e-04638117931182584
Pubmed

Identification of host proteins required for HIV infection through a functional genomic screen.

HEATR1 MND1 LRRC8D ZNF182 ALKBH8 PRKX

3.28e-04272117618187620
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CAD MYO7A SPTA1 RPS9 RTN3 TSC1 ARHGAP35 ARID1A OPA1 DST MTHFD1 LRRCC1 RAPGEF2 CDK5

3.30e-0414311171437142655
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

CAD MYO7A ABCA12 RPS9 LRRK2 ARHGAP35 TRAP1 DST

3.55e-04513117825798074
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

PDS5B NRBP1 EDC3 PPFIBP1 RPS9 TSC1 RO60 HEATR1 ECPAS TRRAP OPA1 ZBTB24 MTHFD1

3.94e-0412841171317353931
Pubmed

Large-scale population-based metabolic phenotyping of thirteen genetic polymorphisms related to one-carbon metabolism.

PON1 MTHFD1

3.98e-049117217436311
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PDS5B TBC1D30 NINL WDFY3

4.01e-04102117410231032
Pubmed

A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.

CAD MTHFD1 GLE1

4.44e-0444117326471122
Pubmed

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.

CAD EDC3 PPFIBP1 SPTA1 RAPGEF2

4.72e-04190117515161933
Pubmed

Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.

RPS9 RTN3 HEATR1 ECPAS OPA1 ZBTB24 LTN1

4.76e-04408117733766124
Pubmed

Postnatal refinement of auditory hair cell planar polarity deficits occurs in the absence of Vangl2.

MYO7A PCNT

4.96e-0410117223986237
Pubmed

The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor.

NCOA2 ARID1A

4.96e-0410117217363140
Pubmed

Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis.

LRRK2 NEK1

4.96e-0410117229891719
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

EDC3 COL16A1 CENPC PPFIBP1 ARHGAP35 NEK1 MTCL1 MBD5 CLUH

5.52e-04689117936543142
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NCOA2 CAD HEATR1 ARHGAP35 ARID1A TRRAP NEK1 SEC23IP

5.55e-04549117838280479
Pubmed

Identification of DeltaNp63alpha protein interactions by mass spectrometry.

CAD CENPE GOLGA4

5.75e-0448117320085233
Pubmed

Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation.

LRRC8D OPA1 ALKBH8 AEBP2 MAPK7 RPL3L

6.00e-04305117621244100
Pubmed

LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome.

CENPF PCNT

6.05e-0411117211163258
Pubmed

Proteomic profiling of Myc-associated proteins.

PDS5B TRRAP OPA1 MLH3

6.10e-04114117421150319
Pubmed

Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes.

TRAP1 TMCC2 PPP1R16A

6.11e-0449117319019082
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

PDS5B ECPAS OPA1 TRAP1 VPS33B SEC23IP LTN1 CLUH

6.32e-04560117835241646
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

PDS5B CAD CENPF HEATR1 TRRAP STXBP2 VPS33B LTN1 CDK5

6.43e-04704117929955894
Pubmed

The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.

TAS2R20 TAS2R19

7.24e-0412117212379855
Pubmed

A new meiosis-specific cohesin complex implicated in the cohesin code for homologous pairing.

CENPC STAG3

7.24e-0412117221274006
Pubmed

Identification and characterization of the potential promoter regions of 1031 kinds of human genes.

TBXAS1 CENPE STXBP2

7.27e-0452117311337467
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

CENPC CENPE CENPF MTCL1 PCNT

7.41e-04210117516565220
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

PDS5B PPFIBP1 APTX NMRAL1 TRRAP SEC23IP OASL GOLGA4 PPP1R16A

7.46e-04719117935337019
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

NCOA2 CENPE LRRK2 HEATR1 ARMCX2 OPA1 ZNF182 SEPSECS LTN1 RAPGEF2 MCUB PPP1R16A

8.25e-0412151171215146197
Pubmed

Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.

TAS2R20 TAS2R19

8.54e-0413117215938754
Pubmed

Delineating WWOX Protein Interactome by Tandem Affinity Purification-Mass Spectrometry: Identification of Top Interactors and Key Metabolic Pathways Involved.

RO60 TRAP1 SEC23IP LRRCC1 RAPGEF2

8.59e-04217117530619736
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

CENPF ARID1A TRAP1 DST DENND6B MTCL1

9.31e-04332117637433992
Pubmed

The c-Jun N-terminal kinase activator dual leucine zipper kinase regulates axon growth and neuronal migration in the developing cerebral cortex.

MAP3K12 CDK5

9.94e-0414117217108173
Pubmed

Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3.

TBC1D30 STXBP2

9.94e-0414117226553929
Pubmed

Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients.

ECPAS WDR87

9.94e-0414117228878358
Pubmed

Interactome Analysis Reveals a Novel Role for RAD6 in the Regulation of Proteasome Activity and Localization in Response to DNA Damage.

SPTA1 RPS9 RO60 CDK5

1.03e-03131117428031328
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

CENPF PPFIBP1 MAEA HEATR1 ECPAS SEPSECS LTN1 NINL PCNT

1.04e-03754117933060197
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

PDS5B SETX NFKBIZ ARMCX2 ARID1A TRRAP AEBP2

1.08e-03469117727634302
Pubmed

Cold-inducible RBM3 inhibits PERK phosphorylation through cooperation with NF90 to protect cells from endoplasmic reticulum stress.

NFKBIZ RO60 UBR3

1.10e-0360117326472337
InteractionGAN interactions

SPTA1 RPS9 TRRAP TRAP1 DST MTHFD1 NINL CLUH PCNT

1.29e-052531139int:GAN
InteractionYWHAB interactions

NRBP1 EDC3 CENPE PPFIBP1 LRRK2 RTN3 TSC1 TRRAP NEK1 DST FAM13A VPS33B CCSER2 NINL MTCL1 RAPGEF2 MAPK7 PDE7B

1.34e-05101411318int:YWHAB
InteractionRNF123 interactions

EDC3 SETX TBC1D30 CENPE CENPF MYO7A RPS9 LCA5L ZBTB41 ECPAS JAK2 FRY DST MTHFD1 ZNF408 MTCL1

1.43e-0582411316int:RNF123
InteractionGPR17 interactions

PDS5B SETX PPFIBP1 HEATR1 ECPAS OPA1 LTN1 UBR3 WDFY3

3.12e-052831139int:GPR17
GeneFamilyTaste 2 receptors

TAS2R33 TAS2R36 TAS2R20 TAS2R19

1.71e-05397241162
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

NCOA2 PDS5B SETX CENPC CENPE CENPF ARHGAP35 TRRAP OPA1 NEK1 DST LTN1 CCSER2 MTCL1 WDFY3 RAPGEF2 GOLGA4 PCNT

2.74e-0885611318M4500
CoexpressionGSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN

NCOA2 TBXAS1 GALNT3 RO60 ARHGAP35 ECPAS PPP1R16B

2.48e-051981137M6511
CoexpressionGSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_DN

KANSL1L PPFIBP1 NFKBIZ CFAP210 ARMCX2 JAK2 OASL

2.64e-052001137M9839
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

CENPC CENPF ZBTB24 MLH3 DST MTCL1 WDFY3 RAPGEF2

4.85e-053001138M8702
CoexpressionBROWNE_HCMV_INFECTION_2HR_DN

CENPE CENPF IFIT2 DST

5.50e-05481134M521
CoexpressionGSE6259_DEC205_POS_DC_VS_BCELL_DN

CENPC NMRAL1 IFIT2 GBP4 RAPGEF2 PDE7B

1.03e-041721136M6772
CoexpressionLAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS

PDS5B IL1RAPL1 DST UBR3 RAPGEF2 PDE7B

1.21e-041771136M39245
CoexpressionZHANG_BREAST_CANCER_PROGENITORS_UP

PDS5B KANSL1L SETX CENPF TRRAP NEK1 MTHFD1 AEBP2 ZNF814

1.43e-044481139MM1044
CoexpressionLINDGREN_BLADDER_CANCER_WITH_LOH_IN_CHR9Q

SETX APTX TSC1 ECPAS GLE1

1.49e-041161135M8411
CoexpressionBILBAN_B_CLL_LPL_UP

HEATR1 ARMCX2 TRRAP FRY

1.70e-04641134M19930
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

CENPE CENPF TRRAP OPA1 DST CCSER2 MTCL1 RAPGEF2 GOLGA4

1.92e-044661139M13522
CoexpressionMEK_UP.V1_DN

ABCA12 JAK2 LTN1 OASL MTCL1 GOLGA4

1.99e-041941136M2724
CoexpressionGSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN

KANSL1L SETX IFIT2 JAK2 OASL MCUB

2.23e-041981136M8969
CoexpressionGSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP

NCOA2 JAK2 NEK1 PPP1R16B MTCL1 WDFY3

2.23e-041981136M3200
CoexpressionGSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP

TRIM49 NFKBIZ ARMCX2 ARID1A CCSER2 OASL

2.23e-041981136M5856
CoexpressionGSE3982_NEUTROPHIL_VS_TH2_DN

COL16A1 CENPF ARMCX2 DST MTHFD1 PCNT

2.23e-041981136M5535
CoexpressionGSE3982_CTRL_VS_LPS_4H_MAC_DN

KANSL1L IFIT2 CSRNP2 CCSER2 OASL GOLGA4

2.29e-041991136M5368
CoexpressionGSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_DN

SETX SPTA1 IFIT2 CSRNP2 SEC23IP OASL

2.29e-041991136M5206
CoexpressionGSE7548_NAIVE_VS_DAY7_PCC_IMMUNIZATION_CD4_TCELL_DN

SETX SPTA1 IFIT2 CSRNP2 OASL RAPGEF2

2.29e-041991136M6837
CoexpressionGSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_UP

ARMCX2 LRRC8D GBP4 LRRCC1 MCUB TPH1

2.29e-041991136M5692
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP

SETX GALNT3 TSC1 RO60 ECPAS LRRC8D OPA1 JAK2 FAM13A LTN1 PPP1R16B ZNF814 RAPGEF2 MCUB GOLGA4

2.30e-04121511315M41122
CoexpressionHOWARD_PBMC_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_19_39YO_AS03_ADJUVANT_VS_BUFFER_1DY_UP

LRRK2 IFIT2 PKHD1L1 JAK2 GBP4 OASL WDFY3 TDRD6

2.34e-043771138M40997
CoexpressionGSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN

PLK2 CENPC RO60 IFIT2 AEBP2 GOLGA4

2.35e-042001136M5130
CoexpressionGSE8835_HEALTHY_VS_CLL_CD8_TCELL_DN

NFKBIZ RO60 CFAP210 ECPAS GBP4 OASL

2.35e-042001136M6263
CoexpressionGSE22886_TH1_VS_TH2_48H_ACT_DN

SETX RTN3 ZBTB24 JAK2 MBD5 PRKX

2.35e-042001136M4512
CoexpressionGSE13306_RA_VS_UNTREATED_TREG_UP

KANSL1L ALKBH8 MTHFD1 GLE1 LRRCC1 TPH1

2.35e-042001136M3232
CoexpressionGSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP

CENPE CENPF NMRAL1 MND1 ARL6 LRR1

2.35e-042001136M3580
CoexpressionGSE17721_CTRL_VS_PAM3CSK4_6H_BMDC_DN

KANSL1L JAK2 GBP4 WDFY3 RPL3L TPH1

2.35e-042001136M3742
CoexpressionGSE33424_CD161_INT_VS_NEG_CD8_TCELL_UP

NMRAL1 CFAP210 IFIT2 MTHFD1 OASL PDE7B

2.35e-042001136M8554
CoexpressionGSE18893_TCONV_VS_TREG_24H_CULTURE_DN

CENPE CENPF LRRK2 IFIT2 ARL6 OASL

2.35e-042001136M7289
CoexpressionGSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_DN

PLK2 LCA5L NFKBIZ GBP4 AEBP2 RAPGEF2

2.35e-042001136M8643
CoexpressionGSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN

TBXAS1 SPTA1 TSC1 IL1RAPL1 LRRCC1 WDFY3

2.35e-042001136M7495
CoexpressionGSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP

SPTA1 TSC1 NEK1 MTHFD1 NINL WDFY3

2.35e-042001136M7525
CoexpressionGSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_DN

PDS5B CENPF RTN3 LRR1 SEC23IP RAPGEF2

2.35e-042001136M3067
CoexpressionFISCHER_DREAM_TARGETS

PDS5B CAD CENPC CENPE CENPF HEATR1 MND1 OPA1 LRR1 MTHFD1 ZNF92 LRRCC1 PCNT

2.81e-0496911313M149
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

PDS5B CENPE CENPF RTN3 NFKBIZ ARHGAP35 ECPAS ARID1A MAP3K12 NEK1 UBR3 WDFY3 RAPGEF2

1.87e-0562910813Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
ToppCelldroplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE CENPF LRR1 SEPSECS NEK5 LRRCC1 STAG3

2.47e-07165115796f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCellcontrol-Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TBXAS1 LRRK2 RTN3 NFKBIZ ARID1A FAM13A MS4A6A

9.02e-072001157b5d197472799cc61d7497faed91ac2564ae4930a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF521 ARMCX2 IFIT2 FRY OASL LRRCC1

1.13e-06130115692913960e4367261ba08a405b61a421bc5e18169
ToppCellControl-Myeloid-Mast|World / Disease state, Lineage and Cell class

GALNT3 ZNF521 MTCL1 RAPGEF2 PDE7B PRKX

5.51e-061711156ed8e61d524f4cddc6084b261175df54d2a64a60f
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EDC3 CENPE CENPF HEATR1 ECPAS PCNT

8.38e-061841156a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EDC3 CENPE CENPF HEATR1 ECPAS PCNT

8.38e-061841156081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

EDC3 CENPE CENPF HEATR1 ECPAS PCNT

8.38e-06184115645f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

EDC3 CENPE CENPF HEATR1 ECPAS PCNT

8.38e-06184115684c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EDC3 CENPE CENPF HEATR1 ECPAS PCNT

8.38e-061841156d31d4116d1d196633784863781fa45673607a421
ToppCellControl-immature_Neutrophil-|Control / Disease condition and Cell class

EDC3 CENPE CENPF HEATR1 ECPAS PCNT

8.38e-061841156c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCellControl-immature_Neutrophil|Control / Disease condition and Cell class

EDC3 CENPE CENPF HEATR1 ECPAS PCNT

8.38e-0618411562fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIBP1 MND1 IFIT2 LRRC9 SEPSECS GBP4

8.92e-0618611564ae3c0fe8640a8d029875cf3f0f5ffbba38e85f8
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-classical_monocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LRRK2 RTN3 IFIT2 STXBP2 OASL MS4A6A

9.77e-061891156cce6602ad68c177985a5e43cfb2776d615cfbca0
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

NCOA2 KANSL1L FRY WDFY3 MBD5 PDE7B

9.77e-061891156830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellCOVID-19-Myeloid-MoAM1,_IL1R2|Myeloid / Condition, Lineage and Cell class

IFIT2 JAK2 GBP4 OASL RAPGEF2 MS4A6A

1.07e-051921156be9d5685fa03563322f147a4b38ed31e4da59487
ToppCellerythropoietic-Basophilic_Erythroblast|World / Lineage and Cell class

CENPF SPTA1 MND1 TRAP1 MTHFD1 LRRCC1

1.27e-051981156b3db4db02c0e659163cefb3d83f53e4940cc04bf
ToppCellsystemic_lupus_erythematosus-treated-Myeloid|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TBXAS1 LRRK2 RTN3 IFIT2 STXBP2 MS4A6A

1.27e-051981156f37578f156e8aed2ce30cfa837ae04dd18de05d0
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRRK2 RTN3 NFKBIZ STXBP2 WDFY3 MS4A6A

1.27e-051981156df546a9afc0e15398f33c1b511c7281771f9aea0
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

EDC3 CENPE CENPF HEATR1 GOLGA4 PCNT

1.35e-052001156118321ac443feb42aee171baccfc4610f00a8822
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TBXAS1 LRRK2 RTN3 NFKBIZ STXBP2 MS4A6A

1.35e-0520011566da31ce0a70ad5621444d731c082c0db572c20c5
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SETX CENPC NFKBIZ JAK2 OASL GOLGA4

1.35e-05200115612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellerythropoietic-Polychromatic_Erythroblast|erythropoietic / Lineage and Cell class

CENPF SPTA1 RO60 FAM13A LRRCC1 GOLGA4

1.35e-05200115627056f28328df2a51d5634a7927b7084241e3ca2
ToppCellmild-CD163+_Monocytes_(Sample_ID1_d7)|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LRRK2 IFIT2 JAK2 STXBP2 OASL MS4A6A

1.35e-05200115699eb02f974ddc8d1882f4a5b34d4503d6ec0a5f5
ToppCellCOVID-19-kidney-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPFIBP1 ZNF521 PKHD1L1 OR52I2 PDE7B

4.13e-051481155f777aa1674e898e2594b2b7c029d3d05dda04df9
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBXAS1 JAK2 LRR1 STXBP2 MCUB

6.53e-0516311557af3d3ae7e0de733a18d0486c7ffbb5a7ef7230a
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPF IFIT2 LRR1 GBP4 OASL

6.53e-051631155d005115aa1e1458b51de7eb719794617a4168608
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|390C / Donor, Lineage, Cell class and subclass (all cells)

CENPE CENPF MND1 CFAP210 MS4A6A

6.72e-051641155ad508f53009efdd1dae7abcdb5431387f3f7e7b2
ToppCellsevere-unassigned|World / disease stage, cell group and cell class

NCOA2 ZBTB24 SEPSECS MTHFD1 WDFY3

6.72e-051641155b3a45c150df6594debeeca400cc58d30ef662756
ToppCellsevere-unassigned|severe / disease stage, cell group and cell class

NCOA2 ZBTB24 SEPSECS MTHFD1 WDFY3

6.92e-051651155f9ddd547992fec065d539a1d0305acba8fc7d79c
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBXAS1 CENPE CENPF MYO7A STAG3

6.92e-0516511551dcd6b8aa192baeaa1f7bb334843edab6049b96f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL16A1 CENPE ABCA12 MND1 MAP3K12

7.12e-05166115543f84d3cd58e93ce00c241656c4cba27604b4932
ToppCellfacs-Spleen-nan-24m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 CENPE CENPF SPTA1 TMCC2

7.33e-05167115516bb7293fc8ca582b7cb4450917aff07b34fc70a
ToppCellfacs-Spleen-nan-24m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 CENPE CENPF SPTA1 TMCC2

7.33e-051671155515988c7035c550a2f072430d9d7027869593d17
ToppCellCOVID-19-kidney-Lymphatic_EC|kidney / Disease (COVID-19 only), tissue and cell type

PPFIBP1 ZNF521 PKHD1L1 OR52I2 PDE7B

7.33e-05167115597d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCellfacs-Spleen-nan-24m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 CENPE CENPF SPTA1 TMCC2

7.33e-051671155f12d00e6c600b0bba3e4e1b1c80b791e095de931
ToppCellControl-Myeloid-Mast|Control / Disease state, Lineage and Cell class

GALNT3 ZNF521 MTCL1 PDE7B PRKX

7.97e-0517011559a14deb7f7cd4a49c217eba4023f7bf1dec6c902
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBXAS1 CENPE CENPF JAK2 MCUB

7.97e-0517011559e94fa0d05abed3438b28296a293767096d517d6
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE CENPF SPTA1 LRR1 TMCC2

8.19e-051711155ff117bf1a0755aa7d7c3db29749a7b9b90cc0b2f
ToppCellImmune_cells-pro-B|Immune_cells / Lineage and Cell class

KANSL1L MYO7A DST PPP1R16B RPL3L

8.42e-051721155096636f2589fa56d15942aac96641c16fd5fa78d
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE CENPF SPTA1 LRR1 TMCC2

8.42e-05172115595219814e37259e34be053572cc95d4639360c27
ToppCelldroplet-Spleen-SPLEEN-30m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE CENPF SPTA1 LRR1 TMCC2

8.42e-05172115502cc4a9fb7902c572cee37ba828749db4913ee87
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA2 CFAP210 ZNF182 RPL3L PDE7B

8.89e-051741155c58328c2f262506a4518f49f148e29874faf9171
ToppCellControl-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

GALNT3 ZNF521 MTCL1 PDE7B PRKX

9.38e-0517611550c5916d63e1ada09105e46d2429b75129b7329ec
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRK2 ZNF521 CCDC168 LRRC4C PDE7B

9.38e-05176115540993c41c1017b53039a337174fc56632b278609
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

PPFIBP1 ZNF521 PKHD1L1 PPP1R16B PDE7B

9.89e-051781155c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac|lymph-node_spleen / Manually curated celltypes from each tissue

CENPE CENPF MND1 WDFY3 MS4A6A

1.04e-0418011554eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPFIBP1 ZNF521 PKHD1L1 DST PDE7B

1.10e-04182115553c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPFIBP1 ZNF521 PKHD1L1 DST PDE7B

1.13e-0418311554d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

NFKBIZ IFIT2 DST GBP4 OASL

1.13e-0418311558f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellIPF-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

GALNT3 ZNF521 MTCL1 PDE7B PRKX

1.16e-0418411557326a16d7d3ae41b8c9d2beaec7f977b374f3469
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TBXAS1 PPFIBP1 RTN3 DST MS4A6A

1.19e-041851155ae966929fb5bbb08ffcbac76cb21941638727f55
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TBXAS1 PPFIBP1 RTN3 DST MS4A6A

1.19e-0418511553beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TBXAS1 PPFIBP1 RTN3 DST MS4A6A

1.19e-041851155ceff11cfa679147ccfd0a0f8079e697a6bea34d9
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 GALNT3 MYO7A DST RPL3L

1.19e-041851155afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 GALNT3 MYO7A DST RPL3L

1.19e-041851155775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TBXAS1 PPFIBP1 RTN3 DST MS4A6A

1.19e-0418511559aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TBXAS1 PPFIBP1 RTN3 DST MS4A6A

1.19e-04185115542939b294ea3e871274d8b73124c850dc1904fd2
ToppCellSevere_COVID-19-Myeloid-transitional_Macro|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

TBXAS1 PPFIBP1 RTN3 DST MS4A6A

1.19e-041851155f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TBXAS1 PPFIBP1 RTN3 DST MS4A6A

1.19e-0418511557a3612520ae4f0cd61480eadba31eecce001419d
ToppCellCOPD-Myeloid-Mast|COPD / Disease state, Lineage and Cell class

GALNT3 MTCL1 RAPGEF2 PDE7B PRKX

1.22e-041861155def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPFIBP1 ZNF521 PKHD1L1 DST PDE7B

1.22e-04186115540070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE CENPF SPTA1 LRR1 TMCC2

1.22e-041861155ac6e32cf07f0f013101ca7aedae0c562857f182b
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE CENPF SPTA1 LRR1 TMCC2

1.22e-0418611557cdcf507a9a1349ed2cf62b79116367c3fc732dd
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CENPE CENPF PPFIBP1 ZNF521 MND1

1.22e-0418611555d527050cd554cc46c6d8dcb7981900725d79fc6
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating-Lymphatic_EC_proliferating_L.2.5.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CENPE CENPF PPFIBP1 ZNF521 MND1

1.22e-041861155ee1c3e2adfa2900542200a218746b576c7ed10dc
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE CENPF SPTA1 PKHD1L1 LRR1

1.25e-041871155dceca7ae3dae96078cccc17a0d8a61b06fa6dffb
ToppCell343B-Lymphocytic-ILC-ILC-1|343B / Donor, Lineage, Cell class and subclass (all cells)

MYO7A HEATR1 ZNF814 CLUH PRKX

1.28e-0418811558f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

PPFIBP1 ZNF521 PKHD1L1 PPP1R16B PDE7B

1.28e-04188115580910dcbb51990f2baed240f319456c0d3fa2065
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PPFIBP1 ZNF521 PKHD1L1 PPP1R16B PDE7B

1.28e-0418811552db80767903703e7e0a1a37c598f7877a909ee94
ToppCellNS-critical-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CENPE CENPF MND1 LRR1 TAS2R19

1.31e-041891155d6bd46abb072b13a6b72f1ca25d19f218cceb1ff
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PPFIBP1 ZNF521 PKHD1L1 PPP1R16B PDE7B

1.31e-0418911550d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PPFIBP1 ZNF521 PKHD1L1 PPP1R16B PDE7B

1.31e-04189115555a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRRK2 NFKBIZ CFAP210 LRRC4C PDE7B

1.31e-041891155bd91bdfe35294e60d980259b70fe9e60dca2743f
ToppCellCOPD-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

GALNT3 MTCL1 RAPGEF2 PDE7B PRKX

1.34e-041901155379dbac19110b76079a7a53209569e060a852acb
ToppCellIPF-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

TBXAS1 RPS9 LRRK2 STXBP2 MS4A6A

1.34e-041901155ffa890138394f579fee53fcfac6c121bf86adc26
ToppCellLeuk-UTI-Myeloid-CD14_Mono|Leuk-UTI / Disease, Lineage and Cell Type

RPS9 LRRK2 RTN3 STXBP2 MS4A6A

1.44e-041931155d1eac8627d00629ed2e81d3b86778007304efcb7
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast|World / Lineage, cell class and subclass

CENPE CENPF SPTA1 MND1 LRRCC1

1.48e-041941155008bb0072f414a48d052429101bdc990ee4f80c2
ToppCellCOPD-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

PPFIBP1 ZNF521 PKHD1L1 DST PDE7B

1.52e-041951155e91ce548ae7224661ee5d2f2639794a5f69798ee
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TBXAS1 LRRK2 RTN3 STXBP2 MS4A6A

1.52e-0419511559f7dc9328d244291baf92b03c346c2189b58e7c4
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

CENPE CENPF SPTA1 MND1 PCNT

1.52e-041951155764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellNS-moderate-d_16-33-Myeloid-Monocyte-derived_Macrophage|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IFIT2 STXBP2 GBP4 OASL GOLGA4

1.52e-041951155d87c83d2d421c9291d0a10bc9db850e9fb337667
ToppCellControl-Neu_4|Control / 5 Neutrophil clusters in COVID-19 patients

EDC3 CENPC CENPE HEATR1 PCNT

1.55e-041961155b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCellSepsis-Int-URO-Lymphocyte-B-Plasmablast|Int-URO / Disease, condition lineage and cell class

PLK2 EDC3 CENPE CENPF PKHD1L1

1.55e-041961155e65b47d0ce1a5dd05f5f50e1639c8ec76fb42dc8
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPE CENPF MND1 LRR1 LRRCC1

1.55e-041961155f70a2b227716a0df3c1aa6a414b822e63f209a43
ToppCellBL-critical-LOC-Myeloid-Neutrophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LRRK2 NFKBIZ IFIT2 STXBP2 WDFY3

1.55e-041961155f64d7fed31e418c55fe946744d78c3cbecec9bbf
ToppCellControl-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

PPFIBP1 ZNF521 PKHD1L1 DST PDE7B

1.55e-041961155e0cf617b0f5d9c3c19574f587a3d0ccbf93d8ca4
ToppCelldistal-Endothelial-Lymphatic-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MYO7A PPFIBP1 SPTA1 PKHD1L1 PDE7B

1.55e-041961155b0f23dc802a2c2a56a08d398a464ea78b58ade4c
ToppCell(000)_CD14+_Monocyte|World / immune cells in Peripheral Blood (logTPM normalization)

TBXAS1 LRRK2 RTN3 STXBP2 MS4A6A

1.59e-041971155cff498bc7b153f28dd013eaeb73ead4fb62fb44c
ToppCellICU-SEP-Myeloid-CD14_Mono|ICU-SEP / Disease, Lineage and Cell Type

RPS9 LRRK2 RTN3 STXBP2 MS4A6A

1.59e-041971155fd08bb4fe521d758c99b3f2533570739a920e99c
ToppCellCOVID-19_Severe-T/NK_proliferative|COVID-19_Severe / Disease condition and Cell class

CENPE CENPF MND1 LRR1 MTHFD1

1.59e-041971155718a84e9a8248080f2d964e7c6a3ba183ece9592
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TBXAS1 LRRK2 RTN3 STXBP2 MS4A6A

1.59e-0419711552afc23f7394d9b40bdf06527c5e6b553e1b02dca
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TBXAS1 LRRK2 RTN3 JAK2 MS4A6A

1.59e-0419711550050da0d809075fde3a7f17894dbb410b254988c
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TBXAS1 LRRK2 RTN3 STXBP2 MS4A6A

1.59e-04197115515bcfe6105c0b508811fb9bba0bc4312fea04f4c
ToppCellerythropoietic-Polychromatic_Erythroblast|World / Lineage and Cell class

CENPE CENPF SPTA1 FAM13A LRRCC1

1.59e-041971155604fcbf47f073c2af344e1b16b615a78ef838dc9
ToppCellnormal-na-Myeloid-classical_monocyte-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

LRRK2 RTN3 NFKBIZ STXBP2 MS4A6A

1.63e-04198115558aa5041077fe17ca01c5e6da077d8008d5123ab
ToppCell(00)_Monocyte|World / immune cells in Peripheral Blood (logTPM normalization)

TBXAS1 LRRK2 RTN3 STXBP2 MS4A6A

1.63e-0419811552252e756a8a25d32c16a723e833c1390a772c2a4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TBXAS1 LRRK2 RTN3 STXBP2 MS4A6A

1.63e-041981155110f7ebb3e1ec19508d4d2b973e1f64e7bdbb5b5
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-classical_monocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LRRK2 RTN3 IFIT2 JAK2 MS4A6A

1.63e-041981155c79c1738560d78b63dbed5f2f9621dbc1c2363cb
ToppCellPBMC-Convalescent-Myeloid|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TBXAS1 LRRK2 NFKBIZ STXBP2 MS4A6A

1.63e-0419811553973bbc1bfb5b08dd1becd5e4bb5899b15df9e55
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-classical_monocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LRRK2 RTN3 IFIT2 JAK2 MS4A6A

1.63e-0419811551d1c80569f1e307285ba0ebaf5c72e0b5b538864
DrugRicinine [524-40-3]; Down 200; 24.4uM; HL60; HT_HG-U133A

KANSL1L TBC1D30 CENPF PPFIBP1 ARHGAP35 FAM13A ZNF408 OASL WDFY3

5.24e-0719311392505_DN
DrugCeftazidime pentahydrate [78439-06-2]; Down 200; 6.2uM; PC3; HT_HG-U133A

TBXAS1 RPS9 ARHGAP35 ARID1A MAP3K12 NEK1 MLH3 OASL WDFY3

6.77e-0719911395054_DN
Drugirinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A

NCOA2 PDS5B TBC1D30 CENPE CENPF JAK2 WDFY3 RAPGEF2

2.56e-0617411387530_DN
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

NCOA2 PDS5B SETX TBC1D30 CENPE ARID1A CCSER2 RAPGEF2

3.58e-0618211383887_DN
DrugGW8510; Down 200; 10uM; MCF7; HT_HG-U133A

PLK2 SETX TBC1D30 CENPE CENPF ARID1A CSRNP2 RAPGEF2

4.37e-0618711387080_DN
DrugTracazolate hydrochloride [41094-88-6]; Down 200; 11.8uM; HL60; HT_HG-U133A

TBC1D30 RPS9 MAP3K12 JAK2 MLH3 ZNF408 SEC23IP WDFY3

5.31e-0619211382919_DN
DrugBephenium hydroxynaphthoate [3818-50-6]; Down 200; 9uM; MCF7; HT_HG-U133A

KANSL1L ABCA12 ARHGAP35 ZNF408 CCSER2 OASL WDFY3 PRKX

5.52e-0619311385628_DN
DrugEtofenamate [30544-47-9]; Down 200; 10.8uM; HL60; HT_HG-U133A

NCOA2 EDC3 TBC1D30 ARID1A IFIT2 JAK2 CCSER2 PPP1R16B

6.18e-0619611382907_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 TBC1D30 ECPAS ARID1A JAK2 WDFY3 PCNT

3.05e-0517811371672_DN
DrugDigitoxigenin [143-62-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A

SETX TBC1D30 LRRC8D ZBTB24 JAK2 CSRNP2 PRKX

3.40e-0518111373275_DN
DrugDigoxin [20830-75-5]; Down 200; 5.2uM; MCF7; HT_HG-U133A

PLK2 TBC1D30 LRRC8D ZBTB24 JAK2 MLH3 VPS33B

3.52e-0518211375324_DN
DrugGW8510; Down 200; 10uM; MCF7; HT_HG-U133A

PLK2 SETX TBC1D30 CENPE CENPF JAK2 RAPGEF2

3.64e-0518311377062_DN
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

NCOA2 SETX TBC1D30 ARID1A ZBTB24 MLH3 RAPGEF2

3.77e-0518411372321_DN
DrugApigenin [520-36-5]; Down 200; 14.8uM; MCF7; HT_HG-U133A

PDS5B TBC1D30 NEK1 SEC23IP MTCL1 WDFY3 RAPGEF2

4.32e-0518811373257_DN
DrugPrimaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A

PDS5B SETX RO60 ARID1A CCSER2 NINL PRKX

4.32e-0518811374845_DN
DrugLuteolin [491-70-3]; Down 200; 14uM; MCF7; HT_HG-U133A

NCOA2 PDS5B TBC1D30 RO60 JAK2 NEK1 SEC23IP

4.62e-0519011373379_DN
DrugStrophantine octahydrate [11018-89-6]; Down 200; 5.4uM; PC3; HT_HG-U133A

SERHL2 TBC1D30 ECPAS ARID1A LRRC8D WDFY3 PRKX

4.62e-0519011376680_DN
DrugMesalamine [89-57-6]; Down 200; 26.2uM; HL60; HT_HG-U133A

RO60 IFIT2 OPA1 NEK1 PPP1R16B WDFY3 RAPGEF2

4.94e-0519211376162_DN
DrugRoxarsone [121-19-7]; Down 200; 15.2uM; PC3; HT_HG-U133A

TBC1D30 RO60 JAK2 FAM13A OASL MAPK7 STAG3

5.28e-0519411375051_DN
DrugDobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

KANSL1L CENPF MYO7A SPTA1 ARID1A TMCC2 MAPK7

5.45e-0519511375386_UP
DrugIsradipine [75695-93-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A

NCOA2 KANSL1L MAP3K12 JAK2 ZNF408 MTCL1 WDFY3

5.45e-0519511375447_DN
DrugCefamandole sodium salt [30034-03-8]; Down 200; 8.2uM; PC3; HT_HG-U133A

MAP3K12 JAK2 MLH3 ZNF408 NINL RAPGEF2 MAPK7

5.45e-0519511377394_DN
DrugApomorphine hydrochloride hemihydrate [41372-20-7]; Down 200; 6.4uM; HL60; HG-U133A

PDS5B NRBP1 SETX JAK2 NEK1 ZNF408 RAPGEF2

5.63e-0519611372005_DN
DrugMetampicillin sodium salt [6489-61-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A

NCOA2 KANSL1L ARHGAP35 NEK1 MLH3 MAPK7 PRKX

5.63e-0519611375540_DN
DrugAzaperone [1649-18-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A

NCOA2 CENPF ARID1A MAP3K12 RAPGEF2 PRKX STAG3

5.81e-0519711377231_DN
DrugMyricetin [529-44-2]; Down 200; 12.6uM; PC3; HT_HG-U133A

TBC1D30 CENPF RO60 IFIT2 FAM13A OASL PRKX

6.00e-0519811374090_DN
DrugAlthiazide [5588-16-9]; Up 200; 10.4uM; PC3; HT_HG-U133A

PDS5B KANSL1L MYO7A PON1 RO60 CCDC57 PDE7B

6.00e-0519811374491_UP
DrugChlorpheniramine maleate [113-92-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A

TBC1D30 MYO7A ARHGAP35 ARID1A MAP3K12 NEK1 MAPK7

6.00e-0519811372217_DN
DrugRanitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; PC3; HT_HG-U133A

TBXAS1 COL16A1 TBC1D30 ARID1A MLH3 MAPK7 PRKX

6.20e-0519911376324_UP
DrugIobenguane sulfate; Up 200; 10.8uM; HL60; HG-U133A

CAD SETX TBC1D30 IFIT2 CLUH CDK5 PCNT

6.20e-0519911371729_UP
DrugTrimethoprim [738-70-5]; Down 200; 13.8uM; PC3; HT_HG-U133A

EDC3 COL16A1 TBC1D30 MYO7A ARHGAP35 MLH3 GLE1

6.20e-0519911373678_DN
DrugCinnarizine [298-57-7]; Down 200; 10.8uM; PC3; HT_HG-U133A

EDC3 TRRAP GLE1 SEC23IP CCSER2 WDFY3 STAG3

6.20e-0519911375817_DN
DrugOzagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; MCF7; HT_HG-U133A

PON1 RO60 ARMCX2 CCDC57 OASL MAPK7 RPL3L

6.39e-0520011373503_UP
DrugSulfapyridine [144-83-2]; Down 200; 16uM; PC3; HT_HG-U133A

CENPF ARID1A NEK1 VPS33B CCSER2 WDFY3 RAPGEF2

6.39e-0520011377151_DN
DrugButamben [94-25-7]; Up 200; 20.6uM; MCF7; HT_HG-U133A

NCOA2 RPS9 ECPAS MAP3K12 TMCC2 MAPK7 STAG3

6.39e-0520011376266_UP
DrugCHDM

TSC1 DST

7.30e-0531132CID000007735
DrugWang resin

SPTA1 DST

7.30e-0531132CID000070043
DrugAntigens, Polyomavirus Transforming

NCOA2 SETX CENPF RPS9 NFKBIZ TSC1 ARID1A MAP3K12 OPA1 GLE1 LTN1 PRKX

1.22e-0466811312ctd:D000952
DiseaseSPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 1

SETX APTX

4.20e-0531112C1853761
DiseaseChronic myeloproliferative disorder

CENPE CENPF PCNT

4.80e-05191113C1292778
DiseaseAmyotrophic Lateral Sclerosis

SETX PON1 NEK1 GLE1

6.88e-05581114C0002736
DiseaseSeckel syndrome

CENPE CENPF PCNT

7.57e-05221113C0265202
DiseaseOvarian Serous Adenocarcinoma

LRRK2 TRRAP JAK2

8.69e-05231113C1335177
DiseaseOvarian Mucinous Adenocarcinoma

NRBP1 LRRK2 TRRAP

2.16e-04311113C1335167
DiseaseHereditary spherocytosis

CAD SPTA1

3.87e-0481112C0037889
Diseasethrombosis (implicated_via_orthology)

TBXAS1 JAK2

6.19e-04101112DOID:0060903 (implicated_via_orthology)
DiseaseCiliopathies

MYO7A TSC1 ARL6 NEK1

8.06e-041101114C4277690
DiseaseHematologic Neoplasms

PON1 JAK2

9.03e-04121112C0376545
DiseaseCakut

TRAP1 VPS33B

1.06e-03131112C1968949
Diseasequinate measurement

LRRK2 OR13D1

1.43e-03151112EFO_0021167
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

TSC1 NEK1

1.63e-03161112DOID:0110861 (implicated_via_orthology)
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

NFKBIZ MLH3

2.30e-03191112C1333991
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

NFKBIZ MLH3

2.30e-03191112C2936783
DiseaseProstatic Neoplasms

NCOA2 TBXAS1 GALNT3 CENPF PON1 ARID1A JAK2 GOLGA4

2.32e-036161118C0033578
DiseaseMalignant neoplasm of prostate

NCOA2 TBXAS1 GALNT3 CENPF PON1 ARID1A JAK2 GOLGA4

2.32e-036161118C0376358
Diseasesphingomyelin 22:0 measurement

HEATR1 PDE7B

2.55e-03201112EFO_0010395
DiseaseDown syndrome (is_marker_for)

MTHFD1 PCNT

3.08e-03221112DOID:14250 (is_marker_for)
Diseaseresponse to clopidogrel, cardiovascular event measurement

NCOA2 LRRC4C

3.37e-03231112EFO_0006919, GO_1903493
Diseasesquamous cell lung carcinoma

PDS5B ECPAS LRRC8D FRY

3.55e-031651114EFO_0000708

Protein segments in the cluster

PeptideGeneStartEntry
ERHQLKTKVVHLSKL

AEBP2

466

Q6ZN18
KQIKAKHTLLRHEGI

ALKBH8

21

Q96BT7
KELKHKNIVRLHDVL

CDK5

56

Q00535
KNIVRLHDVLHSDKK

CDK5

61

Q00535
ALVLTLLLKKHTHQK

COL16A1

101

Q07092
ILREHLKEEKLHAKK

CSRNP2

121

Q9H175
IKETVHKLLRRLHLM

ABCA12

2366

Q86UK0
SLKAVAREHLELLKH

APTX

226

Q7Z2E3
KAEHRHRAKILNLKL

GLE1

206

Q53GS7
RLSVLLGLKKKEVHV

ARL6

6

Q9H0F7
TAHLHRDKALLKRLL

DENND6B

386

Q8NEG7
HHDLLVKVKVIKLVN

ARMCX2

616

Q7L311
IRSALLPVLHHKSKK

PDS5B

706

Q9NTI5
LQKHKERIDHIKLLQ

JAK2

941

O60674
KVAKDVSVRLHHELK

MTCL1

426

Q9Y4B5
KISLKHELFRHGILL

LRRC9

536

Q6ZRR7
IIVRLHETLFKTKKL

LTN1

796

O94822
LGKLILLHHKHPERK

ARID1A

2011

O14497
RELKILKHFKHDNII

MAPK7

101

Q13164
HARLLHCVSKQKILL

KANSL1L

221

A0AUZ9
KELLLHIRSHKQKAS

NFKBIZ

121

Q9BYH8
AKLCKRRIEHLKEHS

MAEA

96

Q7L5Y9
QKKREHHLLEKIDHL

MCUB

181

Q9NWR8
ALLTKHTRKVVHDAK

NMRAL1

226

Q9HBL8
QICLALKHVHDRKIL

NEK1

111

Q96PY6
LKHVHDRKILHRDIK

NEK1

116

Q96PY6
LKSLRKLDLSHNHIK

LRR1

176

Q96L50
LEKELGIKHSLHRKK

PPFIBP1

686

Q86W92
GIKHSLHRKKLQLAL

PPFIBP1

691

Q86W92
LKVVSVLHHLSIKRA

PPFIBP1

761

Q86W92
LELLLKERDKHLKEH

GOLGA4

761

Q13439
HKKHLEVLHSLLKEI

DST

4316

Q03001
LLSLVRKLSTHKEVK

ECPAS

966

Q5VYK3
ALKHTIKLLTVIKWH

IL1RAPL1

526

Q9NZN1
KRLVLRTKLHKLIDF

MLH3

256

Q9UHC1
SKALHARKHKLEVLE

MND1

76

Q9BWT6
LTRLKAHLHNKDLRL

PDE7B

291

Q9NP56
LKHIHDRKILHRDIK

NEK5

116

Q6P3R8
EKLETTLRHKHLAFL

FAM205A

771

Q6ZU69
HILTKLNFHLRKKVL

FAM205A

886

Q6ZU69
EKLETTLRHKHLAFL

FAM205BP

501

Q63HN1
HKTAVLLTELKTKLH

JAKMIP3

66

Q5VZ66
RVEKLHLSHNKLKEI

LRRK2

1246

Q5S007
HRILSARLHKIKGLK

LCA5L

141

O95447
LLREHERLLKHKLKV

GBP4

556

Q96PP9
IKVNSFKHLRHLEIL

LRRC4C

91

Q9HCJ2
LHKKLLSVAEKHGLT

EDC3

286

Q96F86
HIKAKLRLLEVLISK

FAM13A

1001

O94988
RAVSKLEKLLKHHLQ

PCNT

3071

O95613
HLTLLLKLEDKLNRH

NRBP1

461

Q9UHY1
HRPTKLKSLLRLVKH

OASL

201

Q15646
EFKVLLLELKHKHDV

PPP1R16B

306

Q96T49
DDKGIHHRKLKKSLI

OPA1

251

O60313
KTQLLKLKRLLHQHD

CCSER2

676

Q9H7U1
LRLHEAEKKHQALLL

CENPF

2701

P49454
SKVIPKNRIHHKLVL

CENPC

716

Q03188
MAHLKRLVKLHIKRH

GALNT3

1

Q14435
FRHLHLKLKRLKLEE

CFAP97D2

46

A0A1B0GU71
IRTLKHKFKTLEKHL

CCDC57

586

Q2TAC2
DLKETDIKHLRKLKH

MAP3K12

156

Q12852
DIKHLRKLKHPNIIT

MAP3K12

161

Q12852
SLKKHLHAEIKVIGT

MS4A6A

36

Q9H2W1
IHKRKIIAVATLHKS

MBD5

101

Q9P267
KLLELIGHAVAHLKK

IFIT2

311

P09913
KRHLEAILTKISLKN

HEATR1

376

Q9H583
EVFEHSKKLLLHLLI

FRY

1681

Q5TBA9
ITLKGKKSLFRHLLH

CCDC168

3811

Q8NDH2
HSIRKLQAHVLLIKA

SERHL2

231

Q9H4I8
TKAKVLLSALERLKH

MTHFD1

351

P11586
LQTKEELKIAHIHLK

CENPE

1231

Q02224
ELRHLKILHVKSNLT

LRRC8D

586

Q7L1W4
EAVKKVLSRHLHLLK

OR13D1

331

Q8NGV5
LLIHHLCINRKKVSL

OR52I2

11

Q8NH67
KLGLAKSIHHARVLI

RPS9

116

P46781
KTELVKKHVLARLLT

RTN3

826

O95197
LISLHLKKRIKSVVL

TAS2R19

116

P59542
LIFHHLKRKAKSVVL

TAS2R20

116

P59543
LIFLHLKKRIKSVVL

TAS2R33

116

P0DSN6
LIFHHLKRKAKSVVL

TAS2R36

116

P0DTE0
LKKKGKEIFHRLHLS

TRIM49

201

P0CI25
KKTVLHKELVIHILD

TDRD6

621

O60522
KSLLHLKTIRHKLLP

PON1

151

P27169
KAAIDHLHQKILKIT

TMCC2

286

O75069
KKRVITLRKSLLVHH

RPL3L

341

Q92901
KKHVRKLHDSSLGLA

FEZF1

416

A0PJY2
RAKLLELKHKHDALL

PPP1R16A

311

Q96I34
LSHVIKKQHRKSTLV

SETX

791

Q7Z333
LKAVLIPHHKGRKRL

SEC23IP

841

Q9Y6Y8
KLLHLEDVVRALEKH

NINL

1061

Q9Y2I6
EKLLKKARIHPFHIL

RO60

311

P10155
KAKKLFLQHIHRLKH

ARHGAP35

316

Q9NRY4
RVALAKDHLKQIKEH

CFAP210

211

Q0VFZ6
KALKVALSHHLVARV

CLUH

1141

O75153
TSLKEKHKILHRLLQ

NCOA2

681

Q15596
KIIKHFIKIALHCRE

RAPGEF2

786

Q9Y4G8
KHVNLLHIESRKSKR

TPH1

41

P17752
LLEVKLTLLHVLHKF

TBXAS1

486

P24557
AHHFVIRKTEELLKK

TSC1

616

Q92574
KSKLIIHQRIHTGEK

ZNF182

526

P17025
AFRVFSILKKHKIIH

ZNF92

321

Q03936
LKKKRSLLNSHILHL

WDFY3

1461

Q8IZQ1
TLHDKHREVRLKCVK

STAG3

351

Q9UJ98
LKKKGKEIFHRLHLS

TRIM49C

201

P0CI26
KAFHAIILLEKHLRE

ZNF521

816

Q96K83
RIKKTLTKHLVIHSD

ZBTB41

706

Q5SVQ8
ATKLRRHLKSHLEDK

ZNF408

591

Q9H9D4
SRLAKVVKTLKEIHL

STXBP2

121

Q15833
KLLRHLKQKDRLLHK

TBC1D30

181

Q9Y2I9
LLKKHKRLEGELVAH

SPTA1

1751

P02549
TRSIVKILHDHKILI

PKHD1L1

3211

Q86WI1
HLDFHVKDLIKKLLV

PRKX

266

P51817
HICHVARKEEILLIK

CAD

1611

P27708
RLDNLKAHLKIHSKE

ZBTB24

501

O43167
LLHLREFDKKKLISV

TRAP1

536

Q12931
KESILSLLIKLHHKL

UBR3

1086

Q6ZT12
RSHEHLIRLLLEKGK

SEPSECS

26

Q9HD40
KIDKEIELHRILHHK

PLK2

126

Q9NYY3
ILDRHLAILSKKHLE

TXNDC9

106

O14530
SKDHIALTLKRLQKI

WDR87

1161

Q6ZQQ6
HLRKELLIAAKHILT

TRRAP

326

Q9Y4A5
LLAHIIAKFAIHKKI

TRRAP

1886

Q9Y4A5
IHKKIVLQVFHSLLK

TRRAP

1896

Q9Y4A5
LKGLKQEHRLLSLHI

VPS33B

331

Q9H267
LFKKKSHLLVHQRIH

ZNF814

696

B7Z6K7
DHLKHLRTLEKTLEK

LRRCC1

516

Q9C099
SVRHKLVHLTLKKKS

MYO7A

1106

Q13402
RLKVVHKGRIHKLVI

MYBPC1

476

Q00872