Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncupric ion binding

ATP13A2 PRNP

3.51e-055382GO:1903135
GeneOntologyMolecularFunctioncholesterol binding

OSBPL7 OSBPL3 SIDT1

1.83e-0458383GO:0015485
GeneOntologyMolecularFunctionsterol binding

OSBPL7 OSBPL3 SIDT1

3.32e-0471383GO:0032934
GeneOntologyMolecularFunctionalcohol binding

OSBPL7 OSBPL3 SIDT1

9.59e-04102383GO:0043178
GeneOntologyMolecularFunctionsteroid binding

OSBPL7 OSBPL3 SIDT1

2.06e-03133383GO:0005496
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

GPD2 ABCC4 PTGR3

2.28e-03138383GO:0016614
GeneOntologyCellularComponentprotein complex involved in cell adhesion

ITGA8 NID1 ITGA5

1.68e-0459383GO:0098636
GeneOntologyCellularComponentvacuole

OSBPL7 FRK C3 MAN2B2 ATP13A2 HPS4 TM9SF1 SIDT1

1.95e-04913388GO:0005773
GeneOntologyCellularComponentvacuolar lumen

FRK C3 MAN2B2 ATP13A2

2.99e-04178384GO:0005775
GeneOntologyCellularComponentlysosome

FRK C3 MAN2B2 ATP13A2 HPS4 TM9SF1 SIDT1

5.68e-04811387GO:0005764
GeneOntologyCellularComponentlytic vacuole

FRK C3 MAN2B2 ATP13A2 HPS4 TM9SF1 SIDT1

5.68e-04811387GO:0000323
GeneOntologyCellularComponentplatelet dense granule

ABCC4 HPS4

6.61e-0421382GO:0042827
GeneOntologyCellularComponentperinuclear endoplasmic reticulum

OSBPL7 OSBPL3

1.27e-0329382GO:0097038
GeneOntologyCellularComponentautophagosome

OSBPL7 ATP13A2 TM9SF1

1.31e-03119383GO:0005776
GeneOntologyCellularComponentintegrin complex

ITGA8 ITGA5

1.54e-0332382GO:0008305
GeneOntologyCellularComponentcell surface

ITGA8 C3 ABCC4 SLC12A1 ITGA5 WNT5A PRNP

3.49e-031111387GO:0009986
DomainIntegrin_alpha

ITGA8 ITGA5

2.19e-0411382PF00357
DomainOxysterol-bd

OSBPL7 OSBPL3

2.63e-0412382IPR000648
DomainOxysterol-bd_CS

OSBPL7 OSBPL3

2.63e-0412382IPR018494
DomainOxysterol_BP

OSBPL7 OSBPL3

2.63e-0412382PF01237
DomainOSBP

OSBPL7 OSBPL3

2.63e-0412382PS01013
DomainIntegrin_alpha_C_CS

ITGA8 ITGA5

4.75e-0416382IPR018184
DomainIntegrin_alpha-2

ITGA8 ITGA5

6.04e-0418382IPR013649
DomainIntegrin_alpha2

ITGA8 ITGA5

6.04e-0418382PF08441
DomainIntegrin_alpha

ITGA8 ITGA5

6.04e-0418382IPR000413
DomainINTEGRIN_ALPHA

ITGA8 ITGA5

6.04e-0418382PS00242
DomainInt_alpha_beta-p

ITGA8 ITGA5

6.74e-0419382IPR013519
DomainInt_alpha

ITGA8 ITGA5

6.74e-0419382SM00191
DomainFG_GAP

ITGA8 ITGA5

9.08e-0422382PS51470
DomainFG-GAP

ITGA8 ITGA5

1.08e-0324382PF01839
DomainFG-GAP

ITGA8 ITGA5

1.08e-0324382IPR013517
DomainIntegrin_dom

ITGA8 ITGA5

1.17e-0325382IPR032695
Domain-

NT5C2 ATP13A2

7.51e-03643823.40.50.1000
DomainHAD-like_dom

NT5C2 ATP13A2

1.13e-0279382IPR023214
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

ITGA8 NID1 ITGA5

6.67e-071638315878328
Pubmed

Complement protein C3 exacerbates prion disease in a mouse model of chronic wasting disease.

C3 PRNP

1.16e-06238224038599
Pubmed

Antibody-mediated inhibition of integrin α5β1 blocks neurotoxic prion peptide PrP106-126-induced activation of BV2 microglia.

ITGA5 PRNP

3.48e-06338222648512
Pubmed

Subfamily III of mammalian oxysterol-binding protein (OSBP) homologues: the expression and intracellular localization of ORP3, ORP6, and ORP7.

OSBPL7 OSBPL3

3.48e-06338214593528
Pubmed

The basement membrane of hair follicle stem cells is a muscle cell niche.

ITGA8 NID1 ITGA5

3.87e-062838321335239
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PLXNA3 KLHL11 NID1 ABCC4 MAN2B2 ITGA5 WNT5A TM9SF1 PRNP

4.47e-06120138935696571
Pubmed

Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.

C3 PRNP

1.16e-05538217947689
Pubmed

Integrins are required for the differentiation of visceral endoderm.

NID1 ITGA5

2.43e-05738219118216
Pubmed

A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors.

ITGA5 TLE1

2.43e-05738215006356
Pubmed

The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.

OSBPL7 OSBPL3

3.24e-05838217428193
Pubmed

The OSBP-related protein family in humans.

OSBPL7 OSBPL3

6.35e-051138211483621
Pubmed

A family of 12 human genes containing oxysterol-binding domains.

OSBPL7 OSBPL3

7.62e-051238211735225
Pubmed

An oxysterol-binding protein family identified in the mouse.

OSBPL7 OSBPL3

7.62e-051238212215260
Pubmed

Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration.

FRK C3

1.05e-041438221665990
Pubmed

Perinatal lethality and endothelial cell abnormalities in several vessel compartments of fibulin-1-deficient mice.

ITGA8 NID1

1.38e-041638211564885
Pubmed

Integrin requirement for hippocampal synaptic plasticity and spatial memory.

ITGA8 ITGA5

1.38e-041638212904471
Pubmed

Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production.

NID1 WNT5A

1.38e-041638216439479
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

NT5C2 GPD2 NID1 PFKL MAN2B2 TLE1 TM9SF1 PRNP

1.44e-04145138830550785
Pubmed

Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs.

NID1 ITGA5

1.76e-041838212571105
Pubmed

ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation.

ITGA8 WNT5A

1.96e-041938226116176
Pubmed

Genetic mapping of 20 novel expressed sequence tags from midgestation mouse embryos suggests chromosomal clustering.

NID1 TLE1

1.96e-04193829070936
Pubmed

IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.

ITGA8 ITGA5

2.18e-042038222687584
Pubmed

Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice.

NID1 WNT5A

2.90e-042338223386589
Pubmed

Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.

ITGA8 ITGA5

2.90e-042338223152823
Pubmed

Identification of proteins that interact with alpha A-crystallin using a human proteome microarray.

SLC25A28 OSBPL3 MYO5C

2.95e-0411838324453475
Pubmed

High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.

NT5C2 ITGA8 NID1 PRNP

3.47e-0430738437499664
Pubmed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.

ITGA8 ITGA5

4.01e-042738231541017
Pubmed

A genetic linkage map of mouse chromosome 2 extending from thrombospondin to paired box gene 1, including the H3 minor histocompatibility complex.

SLC12A1 PRNP

4.63e-04293828617512
Pubmed

Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development.

TLE1 WNT5A

4.96e-043038236305473
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

C3 PFKL MAN2B2 ITGA5

5.32e-0434438430333137
Pubmed

Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.

ITGA8 ITGA5

5.65e-043238223154389
Pubmed

A mutually stimulating loop involving emx2 and canonical wnt signalling specifically promotes expansion of occipital cortex and hippocampus.

TLE1 WNT5A

7.15e-043638215800025
Pubmed

Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay.

ITGA8 SLC12A1

7.56e-043738216319116
Pubmed

Expression profiles and pathway analysis in HEK 293 T cells overexpressing HIV-1 Tat and nucleocapsid using cDNA microarray.

APOBEC1 PRNP

8.83e-044038218051367
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

NID1 FRK C3 MAN2B2 SLC12A1 MYO5C

9.94e-04107038623533145
Pubmed

A gene expression resource generated by genome-wide lacZ profiling in the mouse.

PFKL SLC25A28

1.07e-034438226398943
InteractionFBXO2 interactions

ITGA8 PLXNA3 NID1 SDK2 MAN2B2 ITGA5 PRNP

8.46e-06411377int:FBXO2
InteractionTNC interactions

ITGA8 ITGA5 PRNP

2.72e-0532373int:TNC
InteractionLY86 interactions

PLXNA3 SDK2 MAN2B2 ITGA5 WNT5A

4.55e-05217375int:LY86
Cytoband14q24.3

SYNDIG1L ZDHHC22

2.72e-039338214q24.3
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL7 OSBPL3

1.86e-0412312670
GeneFamilyCD molecules|Integrin alpha subunits

ITGA8 ITGA5

4.28e-04183121160
CoexpressionGSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_UP

GPD2 ITGA8 C3 PFKL ITGA5

6.54e-06183385M7631
CoexpressionCOLINA_TARGETS_OF_4EBP1_AND_4EBP2

C3 ABCC4 PFKL OSBPL3 WNT5A PTGR3

1.21e-05359386M1919
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 SDK2 OSBPL3 MYO5C

5.14e-071863854e94158db52df41d71e67b02b9895a358eebee0f
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 SDK2 OSBPL3 MYO5C

5.28e-0718738558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA8 NID1 C3 COL6A5 SDK2

7.18e-07199385e1f1950d6f840485e263b83dc81b98910be3ae7a
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

ITGA8 C3 COL6A5 SDK2 SLC25A28

7.18e-071993851a0add79f4e34078b3475eb11c85a4234bda197c
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

ITGA8 C3 COL6A5 SDK2 SLC25A28

7.18e-07199385211c3a08f2d484ab7a3368006767289088f0d957
ToppCellClub-club-13|World / Class top

C3 ABCC4 MYO5C SIDT1

1.09e-051623847d18f05a65ac715e62d610df9cc4a26539340dee
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA8 NID1 COL6A5 ABCC4

1.44e-05174384f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 ABCC4 MYO5C

1.61e-05179384fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 ABCC4 MYO5C

1.64e-05180384b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 ABCC4 MYO5C

1.75e-05183384e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 OSBPL3 MYO5C

1.79e-051843847cc5796557379c3d1db078c1aeda40659c6e401c
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 ABCC4 MYO5C

1.79e-05184384ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 ABCC4 MYO5C

1.83e-05185384fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 ABCC4 MYO5C

1.83e-05185384929b68b05b7686341329ac756d7df172cb4b810b
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SYNDIG1L C3 ABCC4 MYO5C

1.87e-05186384acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GPD2 FRK ABCC4 OSBPL3

1.87e-05186384a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 ABCC4 MYO5C

1.87e-05186384e83718fabb057100835d3357df407f283d23fe16
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 ABCC4 MYO5C

1.95e-051883844bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GPD2 FRK ABCC4 OSBPL3

1.95e-05188384e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNDIG1L NID1 SDK2 WNT5A

1.95e-05188384ee572246e0c2f41bdbc29a03edc67b831af95c09
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 ABCC4 MYO5C

1.95e-0518838443a0508d2524a5b310e89e9422843dcaab999bc3
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 OSBPL3 MYO5C

1.99e-051893845f883ef4cc0383142d538ae61f4fb40dfdb8ef18
ToppCellfacs-GAT-Fat-24m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID1 C3 COL6A5 PRNP

2.03e-051903843720e64129f3f3268b1dc14031a76f41c38241c2
ToppCellPND14-Epithelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C3 CFAP251 PRNP MYO5C

2.03e-05190384f1eeef8f201bf7b96c020c8ab53dd7e05b3060ea
ToppCellfacs-GAT-Fat-24m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID1 C3 COL6A5 PRNP

2.03e-0519038473a50426f972f08f9bb525ad5c0b774187ab5d6a
ToppCellfacs-GAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID1 C3 COL6A5 PRNP

2.03e-05190384b55cf1fb586b724295b7b038483249847bb344fc
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA8 NID1 COL6A5 SDK2

2.12e-05192384162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCelldroplet-Fat-Mat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID1 C3 WNT5A PRNP

2.16e-05193384ebd090d7801480b3cee45caac3d30cc991836769
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID1 C3 WNT5A PRNP

2.16e-0519338422c58032e58730715224d7934968ce92d150b0e8
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID1 C3 WNT5A PRNP

2.16e-0519338485faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID1 C3 WNT5A PRNP

2.16e-05193384f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID1 C3 WNT5A PRNP

2.16e-05193384573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCellfacs-MAT-Fat-3m-Mesenchymal|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID1 C3 WNT5A PRNP

2.16e-05193384110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

C3 OSBPL3 CSAD MYO5C

2.34e-05197384b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

C3 ABCC4 CSAD MYO5C

2.34e-0519738444a59dfb889577b3160a5b13ada1276771a00241
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

C3 ABCC4 CSAD MYO5C

2.34e-051973841485933986921ff45669d9b7501c8d17050b3e97
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ITGA8 C3 COL6A5 SDK2

2.44e-05199384ba586690f88fd051f449753bfe7603a2cb431782
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ITGA8 NID1 COL6A5 SDK2

2.44e-0519938430d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ITGA8 C3 COL6A5 SDK2

2.44e-0519938438ed3bc7daa993d9edcf3e7834597ebb06dd24f8
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ITGA8 C3 COL6A5 SDK2

2.44e-0519938406a7d874ff7c4616577f6e59d3118717a8c47c00
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

ITGA8 C3 COL6A5 SLC25A28

2.44e-05199384fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

C3 COL6A5 SDK2 SLC25A28

2.44e-051993848b86c69aaf60feff53aa782559cfece7342a23de
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ITGA8 NID1 COL6A5 SDK2

2.44e-05199384a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

C3 ABCC4 CSAD MYO5C

2.48e-05200384e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ITGA8 NID1 COL6A5 SDK2

2.48e-0520038444a68bacdb3d5bf563bd35952176995850933a81
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

C3 OSBPL3 CSAD MYO5C

2.48e-052003842dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

ITGA8 NID1 COL6A5 SDK2

2.48e-05200384a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ITGA8 NID1 COL6A5 SDK2

2.48e-05200384aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ITGA8 NID1 COL6A5 SDK2

2.48e-05200384dc61016c61729f69649cfb21f6264e685ce83dea
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ITGA8 NID1 COL6A5 SDK2

2.48e-05200384a510deaada669e690329183e18df02870bd204b3
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ITGA8 NID1 COL6A5 SDK2

2.48e-05200384dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Slc17a8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SYNDIG1L APOBEC1 WNT5A

7.07e-05943830dc7e645149fa4255cbe1d288524a1ca7ab66376
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PLXNA3 FRK WNT5A

1.07e-0410838375d635fc5bb004418db2e1328c24d96b718f10b1
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PLXNA3 FRK WNT5A

1.07e-041083839c7f3e25facfb54ef0be45044999bc36438bbea0
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Reln_(Cajal-Retzius)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SYNDIG1L TM9SF1 ZDHHC22

1.32e-041163831bfd3b0ec4cb5a04c6dfe7861a544eb277e473a3
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Reln_(Cajal-Retzius)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SYNDIG1L TM9SF1 ZDHHC22

1.32e-04116383a3dcd18807d14e207438f321be62797384fd3907
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SYNDIG1L TM9SF1 ZDHHC22

1.32e-04116383685484ea4cbefb5aff5f0cd999fdfadc5a5676e1
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_ALM_Olfr111_Nxph1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SYNDIG1L SDK2 ITGA5

1.53e-04122383dba1c647172a11381efcb178a23808161908daa3
ToppCell(09)_Ionocytes-(4)_1wkpi|(09)_Ionocytes / shred by cell type and Timepoint

C3 RBSN

1.59e-0422382b35fb230042a027b10ef3e7ef09bf13ea1cdc506
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Mup5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SYNDIG1L SDK2 ITGA5

1.72e-041273836df92f80b8922ca00eb383f79cd8dda4d602adfc
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_ALM_Olfr111_Spon1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SYNDIG1L SDK2 ITGA5

1.72e-04127383cd69ba386796715e87674f8324d2acaad1d4d094
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

C3 ABCC4 OSBPL3

1.85e-041303836434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NID1 FRK APOBEC1

2.06e-04135383e908aacb72a8c340f06cf5b4a6b70c2faac4d027
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SYNDIG1L SDK2 ITGA5

2.30e-0414038317005ca714ba03d7528fe7979ffb4654a46b666c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SYNDIG1L SDK2 ITGA5

2.35e-041413835ef3166c5271aa90fd0633016edfe2c74b835319
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOBEC1 DNAJB8 MYO5C

2.70e-04148383941bad657064b3d37cae8b66df99c1aa1098c088
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK OSBPL3 MYO5C

2.98e-04153383e7a074ea8232bacf924be78a244a8507c7e1ebc8
ToppCell10x5'-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

CFAP251 HPS4 MYO5C

3.04e-041543838a8c3851888ab86ca2b13ccc042cde1fef8d88f8
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|368C / Donor, Lineage, Cell class and subclass (all cells)

GPD2 MYO5C SIDT1

3.16e-0415638325b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-microglial_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

C3 ABCC4 WNT5A

3.21e-04157383d4908cafd8870c1c225817f589ea2bce116ac7ab
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

OSBPL7 FRK OSBPL3

3.34e-04159383655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ITGA8 KLHL11 COL6A5

3.40e-041603830293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ITGA8 KLHL11 COL6A5

3.40e-041603833eaae86fa08f7651021316f8e5811bf48055591e
ToppCellCD8+_Memory_T_cell-FLU-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

KLHL11 PFKL SIDT1

3.52e-0416238376f39935763848ea6e7917b2f9f1432c543063d9
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OSBPL7 WNT5A HPS4

3.72e-041653837c771f22b58989572c939ed127e637ec28dc0dca
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ITGA8 FRK TLE1

3.72e-04165383f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

OSBPL7 LETM2 SDK2

3.85e-04167383f4943fb5001475ddab82a0273bcbb3fa68fdd7bd
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ITGA8 SDK2 ZDHHC22

3.92e-041683833fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCell-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

ITGA8 NID1 COL6A5

3.99e-041693838ebe9a88111c53a09c25a7b6a164a0a17880458d
ToppCell367C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

CFAP251 ATP13A2 SIDT1

4.06e-04170383fbb7019c6fba87326702b51f6819ea1af5f3a9b7
ToppCellnormal-na-Lymphocytic_B-B_plasma-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

ITGA8 ABCC4 OSBPL3

4.06e-04170383c5b87974dfddf9780051f7f5693eeeb0c606a3fe
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Col27a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ITGA8 ABCC4 SDK2

4.13e-04171383d07e2c5f7d7f12c68860d4161d76372de174f1d8
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

ITGA8 FRK TLE1

4.13e-04171383e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellfacs-BAT-Fat-3m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOBEC1 ITGA5 ATP13A2

4.20e-041723835f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1-2_PAX6_SCGN|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNDIG1L SDK2 WNT5A

4.27e-0417338333170a1cc0bc87504d0501fc257a32ff17e02314
ToppCell-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

ITGA8 NID1 COL6A5

4.27e-0417338388be9182fbb1bc83531cd41e59ea57c112a21d54
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL11 ABCC4 SDK2

4.34e-04174383f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ITGA8 SDK2 ZDHHC22

4.41e-04175383c227fc5d1ccb69b82a96a6354913cafaf27d0eec
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCC4 MYO5C SIDT1

4.49e-041763833bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellCOVID-19-Myeloid-MoAM4|COVID-19 / Condition, Lineage and Cell class

C3 ABCC4 WNT5A

4.56e-04177383ca5d0c3d5c700bbe4c2da068eb02be6229afb9a0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNDIG1L SDK2 WNT5A

4.64e-0417838308b4a497aca0aeabf4f6a8a55c05b56417b69e78
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNDIG1L SDK2 WNT5A

4.64e-04178383e86ed30652c2de70f16430f04b78789b87df4af2
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_LGI2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITGA8 NID1 OSBPL3

4.72e-041793838dd10e3a9ab39d9a770cecac6e2ed3676b79e906
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITGA8 NID1 SDK2

4.72e-04179383b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRK C3 MYO5C

4.72e-041793837db6b97a1c4c7a163d5da4351ba36ac1785d9d7b
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NID1 ABCC4 SDK2

4.72e-04179383a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 NID1 WNT5A

4.79e-04180383fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

OSBPL7 NID1 ITGA5

4.79e-0418038340d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCellfacs-Kidney-nan-24m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID1 C3 COL6A5

4.79e-04180383f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNDIG1L NID1 SDK2

4.79e-04180383392bc71a69653ba12de31bed4e9357f181094641
Diseasecolon cancer (biomarker_via_orthology)

APOBEC1 WNT5A

1.16e-0339382DOID:219 (biomarker_via_orthology)
Diseasesex interaction measurement, inflammatory bowel disease

SLC25A28 RAD50

2.30e-0355382EFO_0003767, EFO_0008343

Protein segments in the cluster

PeptideGeneStartEntry
NSGVTIQIMRASEYY

APOBEC1

136

P41238
ASQVMRYADLYAASF

NT5C2

451

P49902
MNLQRSYTVAIAGYA

C3

1181

P01024
MANYYEVLGVQASAS

DNAJB8

1

Q8NHS0
QYMATADRSFTVAVY

CFAP251

706

Q8TBY9
YIRMAASLNAGETTY

RBSN

296

Q9H1K0
RAMLAGATAVYSQFI

RAD50

656

Q92878
MAFYSYNSVLAIART

LETM2

1

Q2VYF4
AARYGAATANYMEVV

GPD2

236

P43304
LYEMTVRNASTAVYA

HPS4

646

Q9NQG7
TDGMASVAAYTYRQH

PLXNA3

411

P51805
LAQYRISMAAYVSGE

PFKL

751

P17858
YVVMNHGRSYTAIST

NID1

461

P14543
AGAFYRSYTTQLTMN

SLC25A28

221

Q96A46
AAMAAAAATTSSYYG

RBM4B

286

Q9BQ04
QMASYFGYTVVVSDV

ITGA8

316

P53708
MDSVALNTAYAYATV

ABCC4

126

O15439
IRSLYNFSGEQMASY

ITGA5

311

P08648
QMASYFGYAVAATDV

ITGA5

321

P08648
AQVASGMAYLESRNY

FRK

336

P42685
MLQSYTAAGYRVVAL

ATP13A2

676

Q9NQ11
AVAVTESYVYVAGSM

KLHL11

401

Q9NVR0
VAMVSYNSGTSYLIR

COL6A5

1801

A8TX70
GGSISNMYAVNLARY

CSAD

151

Q9Y600
QESMRAYAANVYTSV

MAN2B2

46

Q9Y2E5
TGYTAYMVSVAAFNA

SDK2

1691

Q58EX2
RMVYVAAFAISAYAS

OSBPL3

581

Q9H4L5
ERMVYIAAFAVSAYS

OSBPL7

531

Q9BZF2
YVAVVVALAAYMSQN

SYNDIG1L

221

A6NDD5
VVAAAYGCIYASLMA

LRTM2

326

Q8N967
FANAVAVAMYVVGFA

SLC12A1

266

Q13621
MSAAAAAAAVVAYGR

TLE1

401

Q04724
ACLYSMVAGVAYISA

ZDHHC22

136

Q8N966
AYSAYASFAVVIMVT

SIDT1

601

Q9NXL6
ESQAYYQRGSSMVLF

PRNP

221

P04156
AFTYAVSAAGVVNAM

WNT5A

136

P41221
ASARYTVGQAVAYMA

PTGR3

111

Q8N4Q0
VFYYARRSNMSGAVQ

TM9SF1

551

O15321
GKTVSARYAMRYFAT

MYO5C

166

Q9NQX4
ARYAMRYFATVSKSG

MYO5C

171

Q9NQX4