Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionarachidonate binding

CYP4F8 HNF4A CYP4F11

9.60e-05151223GO:0050544
GeneOntologyMolecularFunctionlow voltage-gated calcium channel activity

CACNA1I CACNA1H

1.11e-0431222GO:0008332
GeneOntologyMolecularFunctionheparan sulfate N-deacetylase activity

NDST1 NDST3

1.11e-0431222GO:0102140
GeneOntologyMolecularFunctionicosanoid binding

CYP4F8 HNF4A CYP4F11

1.18e-04161223GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F8 HNF4A CYP4F11

1.18e-04161223GO:0050543
GeneOntologyMolecularFunction[heparan sulfate]-glucosamine N-sulfotransferase activity

NDST1 NDST3

2.20e-0441222GO:0015016
GeneOntologyMolecularFunctionN-acetylglucosamine deacetylase activity

NDST1 NDST3

2.20e-0441222GO:0050119
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F8 CYP4F11

3.66e-0451222GO:0052871
GeneOntologyMolecularFunctionlysophosphatidic acid receptor activity

LPAR3 LPAR4

3.66e-0451222GO:0070915
GeneOntologyMolecularFunctionprotein kinase A binding

ARFGEF2 ARFGEF1 LRBA ACBD3

4.36e-04581224GO:0051018
GeneOntologyMolecularFunctionprotein kinase A regulatory subunit binding

ARFGEF2 ARFGEF1 ACBD3

4.64e-04251223GO:0034237
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

NALCN CACNA1I CACNA1H

5.22e-04261223GO:0005248
GeneOntologyMolecularFunction3'-5' exonuclease activity

POLE WRN CNOT6 CNOT6L

5.29e-04611224GO:0008408
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

POLE WRN SLFN12 QTRT2 RFC1 ZRANB3 NARS2 CNOT6 CNOT6L PUS10 DDX18 TOP2A

5.94e-0464512212GO:0140640
GeneOntologyMolecularFunctionlong-chain fatty acid binding

CYP4F8 HNF4A CYP4F11

6.52e-04281223GO:0036041
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F8 CYP4F11

7.62e-0471222GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F8 CYP4F11

7.62e-0471222GO:0018685
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F8 CYP4F11

1.61e-03101222GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F8 CYP4F11

1.61e-03101222GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F8 CYP4F11

1.61e-03101222GO:0102033
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

CYP4F8 CYP46A1 CYP4F11

1.86e-03401223GO:0016709
DomainARM-type_fold

DOCK1 VPS11 ARMC3 COPB1 MROH2A TOGARAM2 ARFGEF2 ARFGEF1 DOCK5 ARFGEF3 NUP188 LRBA AP4B1 UNC79 XPOT

7.50e-0933912415IPR016024
DomainDCB_dom

ARFGEF2 ARFGEF1 ARFGEF3

1.14e-0641243IPR032629
DomainSec7_C

ARFGEF2 ARFGEF1 ARFGEF3

1.14e-0641243IPR015403
DomainDUF1981

ARFGEF2 ARFGEF1 ARFGEF3

1.14e-0641243PF09324
DomainDCB

ARFGEF2 ARFGEF1 ARFGEF3

1.14e-0641243PF16213
DomainDHR-1_domain

DOCK1 DOCK5 DOCK7

4.53e-05111243IPR027007
DomainDHR_2

DOCK1 DOCK5 DOCK7

4.53e-05111243PS51651
DomainDHR_1

DOCK1 DOCK5 DOCK7

4.53e-05111243PS51650
DomainDHR-2

DOCK1 DOCK5 DOCK7

4.53e-05111243PF06920
DomainDOCK

DOCK1 DOCK5 DOCK7

4.53e-05111243IPR026791
DomainDOCK_C

DOCK1 DOCK5 DOCK7

4.53e-05111243IPR010703
DomainDOCK-C2

DOCK1 DOCK5 DOCK7

4.53e-05111243PF14429
DomainDHR-2

DOCK1 DOCK5 DOCK7

4.53e-05111243IPR027357
DomainARM-like

ARMC3 COPB1 MROH2A TOGARAM2 ARFGEF2 ARFGEF1 LRBA AP4B1 XPOT

8.05e-052701249IPR011989
Domain-

ARMC3 COPB1 TOGARAM2 ARFGEF2 ARFGEF1 LRBA AP4B1 XPOT

1.19e-0422212481.25.10.10
DomainVDCC_T_a1

CACNA1I CACNA1H

1.31e-0431242IPR005445
DomainSEC7

ARFGEF2 ARFGEF1 ARFGEF3

1.50e-04161243PS50190
DomainSec7

ARFGEF2 ARFGEF1 ARFGEF3

1.50e-04161243SM00222
DomainSec7_dom

ARFGEF2 ARFGEF1 ARFGEF3

1.50e-04161243IPR000904
DomainHeparan_SO4_deacetylase

NDST1 NDST3

2.60e-0441242IPR021930
DomainSec7_N

ARFGEF2 ARFGEF1

2.60e-0441242IPR032691
DomainSec7_N

ARFGEF2 ARFGEF1

2.60e-0441242PF12783
DomainHSNSD

NDST1 NDST3

2.60e-0441242PF12062
DomainDOCK_N

DOCK1 DOCK5

4.32e-0451242PF16172
DomainDOCK_N

DOCK1 DOCK5

4.32e-0451242IPR032376
DomainP-loop_NTPase

NDST1 MYO5B WRN RNF213 RFC1 ZRANB3 DNAH1 NDST3 NWD2 DDX18 DSEL PARPBP RAB1A RAB5A RAB5C

5.02e-0484812415IPR027417
DomainIon_trans_dom

TRPC3 NALCN KCNH2 CACNA1I CACNA1H

9.81e-041141245IPR005821
DomainIon_trans

TRPC3 NALCN KCNH2 CACNA1I CACNA1H

9.81e-041141245PF00520
Domain-

NDST1 WRN RNF213 RFC1 ZRANB3 DNAH1 NDST3 NWD2 DDX18 DSEL RAB1A RAB5A RAB5C

1.38e-03746124133.40.50.300
DomainSulfotransfer_1

NDST1 NDST3 DSEL

1.74e-03361243PF00685
DomainSulfotransferase_dom

NDST1 NDST3 DSEL

1.74e-03361243IPR000863
DomainVDCCAlpha1

CACNA1I CACNA1H

1.90e-03101242IPR002077
DomainCyt_P450_E_grp-I

CYP4F8 CYP46A1 CYP4F11

3.31e-03451243IPR002401
DomainClathrin/coatomer_adapt-like_N

COPB1 AP4B1

4.34e-03151242IPR002553
DomainAdaptin_N

COPB1 AP4B1

4.34e-03151242PF01602
Domain-

ARFGEF2 ARFGEF1

4.34e-031512421.10.1000.11
DomainSec7

ARFGEF2 ARFGEF1

4.34e-03151242PF01369
DomainSec7_alpha_orthog

ARFGEF2 ARFGEF1

4.34e-03151242IPR023394
DomainCyt_P450_CS

CYP4F8 CYP46A1 CYP4F11

5.25e-03531243IPR017972
DomainCYTOCHROME_P450

CYP4F8 CYP46A1 CYP4F11

6.44e-03571243PS00086
DomainChannel_four-helix_dom

NALCN CACNA1I CACNA1H

6.44e-03571243IPR027359
Domain-

NALCN CACNA1I CACNA1H

6.44e-035712431.20.120.350
PathwayKEGG_MEDICUS_REFERENCE_EARLY_ENDOSOMAL_FUSION

RABEP1 RAB5A RAB5C

2.01e-0581023M47778
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

CYP4F8 POLE NDN HNF4A GTF3C3 TBC1D4 CNOT6L BABAM1 RHPN2 FANCI RABEP1 NUP188 LRBA TAGLN AP4B1 SNRPB2 PSMD14 UNC79 RAB5A RAB5C

3.43e-0812841252017353931
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

COPB1 ADAR GTF3C3 WTAP TBC1D4 FANCI DOCK7 NUP188 CDC73 PSMD14 ACBD3 RAB5A RAB5C

7.30e-085341251335032548
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DOCK1 COPB1 POLE ARFGEF2 RNF17 CCNB1 DOCK5 BABAM1 FANCI MACF1 CDC73 SNRPB2 TOP2A

1.96e-075821251320467437
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

VPS11 CYP4F8 GCNT3 ARFGEF2 ARFGEF1 RNF213 ACAD10 NARS2 DOCK5 FANCI VPS13A MACF1 NUP188 LRBA RAB1A RAB5A XPOT

2.74e-0710611251733845483
Pubmed

Large-scale profiling of Rab GTPase trafficking networks: the membrome.

RAB1A RAB5A RAB5C

4.51e-075125315944222
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

POLE RBM26 QTRT2 PREPL CCNB1 PTPDC1 BABAM1 FANCI PYGL NUP188 CDC73 PSMD14 ACBD3 RAB5A RAB5C XPOT

4.56e-079741251628675297
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

COPB1 ADAR GTF3C3 TBC1D4 FANCI DDX18 NUP188 CDC73 LRBA PSMD14 ACBD3 RAB5C XPOT

5.53e-076381251333239621
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

CFAP36 SYNE1 POLE TTLL5 RNF213 ADCK2 MRPS18C PREPL NARS2 CCNB1 ARFGEF3 BABAM1 DDX18 VPS13A NUP188 RAB1A ACBD3 TOP2A RAB5C

1.71e-0614961251932877691
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FILIP1 SYNE1 CNOT6 ARFGEF3 NWD2 MACF1

2.05e-06103125610574462
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

ARFGEF2 ARFGEF1 RNF213 ARFGEF3 FANCI XPOT

2.17e-06104125631240132
Pubmed

Identification of rabaptin-5, rabex-5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER.

RABEP1 RAB1A RAB5A

2.50e-068125311718716
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

COPB1 APMAP SYNE1 POLE RBM26 RFC1 ADAR GTF3C3 FANCI DDX18 DOCK7 NUP188 CDC73 SNRPB2 RAB1A PSMD14 TOP2A XPOT

3.57e-0614251251830948266
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

COPB1 RBM26 AIF1L RFC1 ADAR PREPL GTF3C3 TBC1D4 FANCI DOCK7 MACF1 PYGL RAB1A PSMD14 ACBD3 RAB5C

3.87e-0611491251635446349
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

COPB1 POLE RFC1 GTF3C3 FANCI DDX18 DOCK7 MACF1 PYGL NUP188 RAI1 XPOT

4.44e-066531251222586326
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

COPB1 CFAP36 WRN ARFGEF2 ARFGEF1 RNF213 GTF3C3 DOCK5 ARFGEF3 DDX18 VPS13A DOCK7 LRBA

4.82e-067771251335844135
Pubmed

Lysophosphatidic acid induces neurite branch formation through LPA3.

LPAR3 LPAR4 LIPH

5.34e-0610125322465231
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

COPB1 APMAP SYNE1 DNAH1 DDX18 MACF1 LRBA RAB1A PSMD14 UNC79 RAB5A RAB5C XPOT

7.23e-068071251330575818
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

RBM26 WRN RFC1 ADAR PPP1R10 PAPOLA CDC73 TOP2A

9.00e-06283125830585729
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

NDST1 SIKE1 COPB1 ARFGEF2 FANCI RABEP1 KIT XPOT

9.47e-06285125832838362
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

COPB1 RNF213 TBC1D4 VPS13A DOCK7 PKHD1 PYGL

1.09e-05208125733230847
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

COPB1 RNF213 RFC1 ADAR GTF3C3 TXNIP DOCK7 MACF1 PYGL TOP2A XPOT

1.17e-056011251133658012
Pubmed

A T-type calcium channel required for normal function of a mammalian mechanoreceptor.

CACNA1I CACNA1H

1.28e-052125212808460
Pubmed

Rebound burst firing in the reticular thalamus is not essential for pharmacological absence seizures in mice.

CACNA1I CACNA1H

1.28e-052125225071191
Pubmed

CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development.

CNOT6 CNOT6L

1.28e-052125234788619
Pubmed

Whole Exome Sequencing of Hemiplegic Migraine Patients Shows an Increased Burden of Missense Variants in CACNA1H and CACNA1I Genes.

CACNA1I CACNA1H

1.28e-052125236786913
Pubmed

Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex.

ARFGEF2 ARFGEF1

1.28e-052125223918382
Pubmed

Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma.

ARFGEF2 ARFGEF1

1.28e-052125217360629
Pubmed

Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex.

ARFGEF2 ARFGEF1

1.28e-052125210716990
Pubmed

Membrane association of the Arabidopsis ARF exchange factor GNOM involves interaction of conserved domains.

ARFGEF2 ARFGEF1

1.28e-052125218203920
Pubmed

Identification of a mouse B-type cyclin which exhibits developmentally regulated expression in the germ line.

CCNB1 KIT

1.28e-05212521280449
Pubmed

Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle.

TBC1D4 AKT2

1.28e-052125219923418
Pubmed

Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion.

RABEP1 RAB5A

1.28e-05212528521472
Pubmed

Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes.

ARFGEF2 ARFGEF1

1.28e-052125218417613
Pubmed

Structural basis of Rab5-Rabaptin5 interaction in endocytosis.

RABEP1 RAB5A

1.28e-052125215378032
Pubmed

Investigation of Potential Mechanisms Associated with Non-small Cell Lung Cancer.

CCNB1 TOP2A

1.28e-052125232048869
Pubmed

TRPC3 and NALCN channels drive pacemaking in substantia nigra dopaminergic neurons.

TRPC3 NALCN

1.28e-052125234409942
Pubmed

Expression and function of a T-type Ca2+ conductance in interstitial cells of Cajal of the murine small intestine.

CACNA1H KIT

1.28e-052125224477235
Pubmed

Global identification of miR-373-regulated genes in breast cancer by quantitative proteomics.

TXNIP RABEP1

1.28e-052125221271679
Pubmed

The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence.

CNOT6 CNOT6L

1.28e-052125221233283
Pubmed

Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors.

ARFGEF2 ARFGEF1

1.28e-052125210212200
Pubmed

Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle.

TBC1D4 AKT2

1.28e-052125216804077
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK1 DOCK5 DOCK7

1.60e-0514125312432077
Pubmed

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

WRN RFC1 GTF3C3 BABAM1 NUP188 RAI1

1.79e-05150125630154076
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

L3MBTL2 TCN1 COPB1 SYNE1 AIF1L TUBGCP5 GTF3C3 CCNB1 CNOT6 PPP1R10 CNOT6L NUP188 SNRPB2 TOP2A RAB5C

1.80e-0511551251520360068
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

COPB1 ARFGEF2 TBC1D4 BABAM1 PAPOLA FANCI RABEP1 MACF1 PYGL NUP188 CDC73 LRBA SNRPB2 RAB1A PSMD14 ACBD3 XPOT

1.87e-0514551251722863883
Pubmed

A protein interaction landscape of breast cancer.

MYO5B CCNB1 PPP1R10 BABAM1 FANCI MACF1 AKT2 NUP188 CDC73 TOP2A RAB5C

1.92e-056341251134591612
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

FRAS1 SYNE1 ADAR FANCI MACF1 NUP188

1.93e-05152125634299191
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

COPB1 MYO5B APMAP SYNE1 ADAR PPP1R10 DDX18 DOCK7 MACF1 NUP188 SNRPB2 RAB1A TOP2A RAB5C

1.99e-0510241251424711643
Pubmed

Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication.

POLE RFC1 TOP2A

2.00e-0515125312393188
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

SYNE1 RNF213 ADAR WTAP DDX18 DOCK7 NUP188 TOP2A

2.83e-05332125825693804
Pubmed

PD-L1 translocation to the plasma membrane enables tumor immune evasion through MIB2 ubiquitination.

RAB1A RAB5A RAB5C

2.97e-0517125336719382
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

COPB1 CFAP36 APMAP ARFGEF1 QTRT2 RNF213 RFC1 ADAR WTAP DDX18 PYGL TAGLN SNRPB2 RAB1A PSMD14 TOP2A

3.29e-0513671251632687490
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

RBM26 WRN RFC1 ADAR PPP1R10 RAB1A TOP2A RAB5C

3.35e-05340125824332808
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

COPB1 APMAP RBM26 RFC1 ADAR CCNB1 PPP1R10 FANCI TOP2A XPOT

3.66e-055601251035241646
Pubmed

Mutations in UNC80, Encoding Part of the UNC79-UNC80-NALCN Channel Complex, Cause Autosomal-Recessive Severe Infantile Encephalopathy.

NALCN UNC79

3.84e-053125226708753
Pubmed

Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity.

ARFGEF2 ARFGEF1

3.84e-053125219332778
Pubmed

Specific functions of BIG1 and BIG2 in endomembrane organization.

ARFGEF2 ARFGEF1

3.84e-053125220360857
Pubmed

Ethanol inhibition of a T-type Ca²+ channel through activity of protein kinase C.

CACNA1I CACNA1H

3.84e-053125223488970
Pubmed

Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5.

RABEP1 RAB5A

3.84e-05312529524117
Pubmed

Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies).

NALCN UNC79

3.84e-053125230167850
Pubmed

Identification of the t-type calcium channel (Ca(v)3.1d) in developing mouse heart.

CACNA1I CACNA1H

3.84e-053125211230107
Pubmed

AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors.

ARFGEF2 ARFGEF1

3.84e-053125216866877
Pubmed

Mechanism of Rab geranylgeranylation: formation of the catalytic ternary complex.

RAB1A RAB5A

3.84e-05312529730828
Pubmed

Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis.

CNOT6 CNOT6L

3.84e-053125230926667
Pubmed

Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.

CACNA1I CACNA1H

3.84e-053125233547341
Pubmed

Calmodulin regulates Cav3 T-type channels at their gating brake.

CACNA1I CACNA1H

3.84e-053125228972185
Pubmed

Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes.

RAB1A RAB5A

3.84e-053125233692360
Pubmed

CNOT6L couples the selective degradation of maternal transcripts to meiotic cell cycle progression in mouse oocyte.

CNOT6 CNOT6L

3.84e-053125230478191
Pubmed

Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.

CACNA1I CACNA1H

3.84e-053125211897840
Pubmed

Involvement of BIG1 and BIG2 in regulating VEGF expression and angiogenesis.

ARFGEF2 ARFGEF1

3.84e-053125231199673
Pubmed

Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex.

NALCN UNC79

3.84e-053125221040849
Pubmed

Enhancement of β-catenin activity by BIG1 plus BIG2 via Arf activation and cAMP signals.

ARFGEF2 ARFGEF1

3.84e-053125227162341
Pubmed

The Sec7 guanine nucleotide exchange factor GBF1 regulates membrane recruitment of BIG1 and BIG2 guanine nucleotide exchange factors to the trans-Golgi network (TGN).

ARFGEF2 ARFGEF1

3.84e-053125223386609
Pubmed

DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation.

DOCK5 KIT

3.84e-053125224913231
Pubmed

Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex.

NALCN UNC79

3.84e-053125232620897
Pubmed

Delayed onset of positive feedback activation of Rab5 by Rabex-5 and Rabaptin-5 in endocytosis.

RABEP1 RAB5A

3.84e-053125220169068
Pubmed

T-type channels: release a brake, engage a gear.

CACNA1I CACNA1H

3.84e-053125226488564
Pubmed

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis.

RABEP1 RAB5A

3.84e-05312529045618
Pubmed

Differential interactions of Na+ channel toxins with T-type Ca2+ channels.

CACNA1I CACNA1H

3.84e-053125218591418
Pubmed

Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation.

CACNA1I CACNA1H

3.84e-053125228846697
Pubmed

Rab1a and Rab5a preferentially bind to binary lipid compositions with higher stored curvature elastic energy.

RAB1A RAB5A

3.84e-053125223815289
Pubmed

Rab5 isoforms orchestrate a "division of labor" in the endocytic network; Rab5C modulates Rac-mediated cell motility.

RAB5A RAB5C

3.84e-053125224587345
Pubmed

Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function.

TBC1D4 AKT2

3.84e-053125229170369
Pubmed

Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability.

CACNA1I CACNA1H

3.84e-053125211927664
Pubmed

Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family.

NDST1 NDST3

3.84e-05312529915799
Pubmed

Increased expression of cholesterol 24S-hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: a potential role in Alzheimer's disease.

SLC1A2 CYP46A1

3.84e-053125220193040
Pubmed

A C-terminal sequence in the guanine nucleotide exchange factor Sec7 mediates Golgi association and interaction with the Rsp5 ubiquitin ligase.

ARFGEF2 ARFGEF1

3.84e-053125218832381
Pubmed

Thioredoxin-interacting protein mediates sustained VEGFR2 signaling in endothelial cells required for angiogenesis.

TXNIP RAB5A

3.84e-053125223393387
Pubmed

Rab5 is necessary for the biogenesis of the endolysosomal system in vivo.

RAB5A RAB5C

3.84e-053125222622570
Pubmed

Distinct functions for Arf guanine nucleotide exchange factors at the Golgi complex: GBF1 and BIGs are required for assembly and maintenance of the Golgi stack and trans-Golgi network, respectively.

ARFGEF2 ARFGEF1

3.84e-053125218003980
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

COPB1 APMAP POLE QTRT2 RFC1 GTF3C3 WTAP FANCI PYGL NUP188 SNRPB2 PSMD14 ACBD3 RAB5C XPOT

4.75e-0512571251537317656
Pubmed

Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.

ZNF233 ZNF226 ZNF112

4.94e-0520125312743021
Pubmed

SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination.

POLE RFC1 ZRANB3

5.75e-0521125324958773
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

L3MBTL2 WRN ZNF226 RFC1 GTF3C3 PPP1R10 FANCI KDM4A TOP2A RAI1

7.27e-056081251036089195
Pubmed

Lowered expression of heparan sulfate/heparin biosynthesis enzyme N-deacetylase/n-sulfotransferase 1 results in increased sulfation of mast cell heparin.

NDST1 NDST3

7.65e-054125222049073
Pubmed

Human NB-2 of the contactin subgroup molecules: chromosomal localization of the gene (CNTN5) and distinct expression pattern from other subgroup members.

ARFGEF2 ARFGEF1

7.65e-054125211013081
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F8 CYP4F11

7.65e-054125222665481
Pubmed

Exome analysis of Smith-Magenis-like syndrome cohort identifies de novo likely pathogenic variants.

NDN RAI1

7.65e-054125228213671
Pubmed

Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy.

CACNA1I CACNA1H

7.65e-054125228165634
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F8 CYP4F11

7.65e-054125211185557
GeneFamilyLysophosphatidic acid receptors

LPAR3 LPAR4

3.31e-046862205
GeneFamilyCCR4-NOT transcription complex

CNOT6 CNOT6L

1.20e-03118621023
CoexpressionKENNY_CTNNB1_TARGETS_UP

SYNE1 RBM26 ARFGEF2 CCNB1 SERPIND1

3.46e-06501215M11067
CoexpressionDODD_NASOPHARYNGEAL_CARCINOMA_UP

SIKE1 FRAS1 APMAP WRN QTRT2 RNF213 MND1 ZNF112 RFC1 ADAR GTF3C3 CCNB1 SLC44A1 FANCI DDX18 DOCK7 PARPBP PSMD14 TOP2A XPOT

6.77e-06140712120M14427
CoexpressionBORCZUK_MALIGNANT_MESOTHELIOMA_UP

DOCK1 WTAP CCNB1 PAPOLA DDX18 RAB1A ACBD3 TOP2A XPOT

1.43e-053101219M10236
CoexpressionGSE3982_EOSINOPHIL_VS_MAC_UP

NDST1 SYNE1 PPP1R10 SLC44A1 DDX18 KIT SERPIND1

3.73e-051971217M5401
CoexpressionSAKAI_TUMOR_INFILTRATING_MONOCYTES_DN

WRN MACF1 CDC73 SNRPB2 TOP2A

3.74e-05811215M8180
CoexpressionGSE32423_CTRL_VS_IL4_MEMORY_CD8_TCELL_UP

SYNE1 ZNF112 RNF17 NARS2 KCNH2 PYGL LRBA

4.11e-052001217M5085
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000

POLE ARFGEF2 QTRT2 RNF213 MND1 RNF17 ZRANB3 GTF3C3 CCNB1 SLCO4C1 BRDT RHPN2 LIPH FANCI VPS13A NUP188 KIT XPOT

8.42e-0782212018gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000

POLE QTRT2 MND1 RNF17 ZRANB3 GTF3C3 CCNB1 SLCO4C1 BRDT RHPN2 LIPH FANCI DDX18 NUP188 KIT XPOT

1.05e-0579512016gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_500

DOCK1 GCNT3 ARFGEF2 SLCO4C1 PAPOLA RHPN2 KCNJ16 VPS13A PKHD1 LRBA PARPBP

1.35e-0539012011gudmap_developingKidney_e15.5_cortic collect duct_500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

POLE TTLL5 ARFGEF2 MND1 RNF17 ZRANB3 BRDT RHPN2 LIPH FANCI VPS13A NUP188 LRBA PARPBP KIT

6.06e-0582012015gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500

POLE ARFGEF2 MND1 RNF17 BRDT RHPN2 LIPH FANCI VPS13A KIT

6.76e-0538512010gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_500

POLE MND1 RNF17 CCNB1 SLCO4C1 BRDT LIPH FANCI KIT XPOT

7.05e-0538712010gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

CWF19L2 CYP4F8 L3MBTL2 POLE RBM26 ARFGEF2 AIF1L RFC1 ZRANB3 CCNB1 CNOT6L PAPOLA RABEP1 VPS13A DOCK7 MACF1 PARPBP PSMD14 TOP2A

7.93e-05125712019facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_500

POLE MND1 RNF17 ZRANB3 GTF3C3 CCNB1 BRDT LIPH KIT XPOT

8.53e-0539612010gudmap_dev gonad_e13.5_M_GermCell_Oct_500
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_100

DOCK1 GCNT3 SLCO4C1 PKHD1 PARPBP

1.08e-04831205gudmap_developingKidney_e15.5_ureter tip_100_flank cortic collct
CoexpressionAtlasdev gonad_e11.5_M_PrimGermCell_Oct_top-relative-expression-ranked_1000

POLE TTLL5 MND1 RNF17 ZRANB3 CCNB1 SLCO4C1 RHPN2 LIPH FANCI DDX18 NUP188 KIT XPOT

1.34e-0478112014gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000

ZCCHC18 FRAS1 MYO5B POLE MROH2A AIF1L MND1 CCNB1 ARFGEF3 CNOT6L KCNJ16 PYGL LRBA TOP2A

1.38e-0478312014gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000

SYNE1 RBM26 ARFGEF2 ARFGEF1 RNF213 ZNF226 SLC1A2 ZRANB3 WTAP RHPN2 MACF1 KEL LRBA PARPBP KIT ACBD3

1.43e-0498912016Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_top-relative-expression-ranked_1000

POLE ARFGEF2 MND1 RNF17 ZRANB3 GTF3C3 CCNB1 RHPN2 LIPH FANCI DDX18 NUP188 KIT XPOT

1.70e-0479912014gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

CWF19L2 CYP4F8 L3MBTL2 POLE RBM26 ARFGEF2 AIF1L RFC1 ZRANB3 CCNB1 CNOT6L PAPOLA RABEP1 KCNJ16 VPS13A DOCK7 MACF1 PARPBP PSMD14 TOP2A

1.90e-04145912020facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000

POLE QTRT2 RNF213 MND1 RNF17 ZRANB3 GTF3C3 CCNB1 BRDT LIPH DDX18 NUP188 KIT XPOT

1.95e-0481012014gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

POLE TTLL5 ARFGEF2 MND1 RNF17 ZRANB3 FANCI NUP188 PARPBP

2.14e-043611209gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_500

POLE ARFGEF2 MND1 RNF17 LIPH FANCI

2.28e-041521206gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_500
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_200

DOCK1 ARFGEF2 HNF4A KCNJ16 PKHD1 PARPBP

2.53e-041551206gudmap_developingKidney_e15.5_anlage of loop of Henle_200
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#1_top-relative-expression-ranked_500

DOCK1 ARFGEF2 PARPBP

2.87e-04231203gudmap_developingKidney_e15.5_Endothelial cells_500_k1
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_top-relative-expression-ranked_200

DOCK1 GCNT3 RHPN2 KCNJ16 PKHD1 PARPBP

3.00e-041601206gudmap_developingKidney_e15.5_Medullary collecting duct_200
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_top-relative-expression-ranked_200

FILIP1 GCNT3 ART3 LIPH PKHD1 TAGLN

3.10e-041611206gudmap_developingLowerUrinaryTract_P1_bladder_200_J
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#3_top-relative-expression-ranked_500

DOCK1 ARFGEF2 PARPBP

3.70e-04251203DevelopingKidney_e15.5_Endothelial cells_emap-29977_k3_500
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_1000

DOCK1 FILIP1 COPB1 SYNE1 TRPC3 PREPL WTAP PAPOLA NALCN VPS13A PYGL TAGLN PARPBP

4.28e-0477212013gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_1000

DOCK1 GCNT3 ARFGEF2 AIF1L SLCO4C1 PAPOLA RHPN2 KCNJ16 VPS13A PKHD1 CDC73 LRBA PARPBP

4.39e-0477412013gudmap_developingKidney_e15.5_cortic collect duct_1000
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#4_top-relative-expression-ranked_1000

QTRT2 MND1 RNF17 ZRANB3 GTF3C3 LIPH XPOT

4.68e-042431207gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k4_1000
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MYO5B AIF1L SLCO4C1 RHPN2 KCNJ16 PKHD1 LRBA

8.04e-0819612486ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CWF19L2 SYNE1 ARFGEF1 RNF213 ZNF407 VPS13A MACF1 LRBA

9.03e-081991248f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 MROH2A RNF17 DNAH1 NALCN PKHD1 UNC79

4.85e-07169124712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Marrow-B-cells-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 LPAR4 APMAP TTLL5 SLC1A2 RHPN2 CACNA1H

5.46e-071721247a7fd4d61fb5017dce001d69d6b9a01e6cdf58828
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-neutrophil-myelocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TCN1 APMAP SYNE1 POLE TOGARAM2 PREPL PYGL

7.98e-07182124752eac2f892ea7f26731e0b21c578fd2665a1657a
ToppCellBac-SEP-Lymphocyte-T_NK-T_NK_proliferative|Bac-SEP / Disease, Lineage and Cell Type

FILIP1 MND1 STARD6 CCNB1 FANCI PARPBP TOP2A

8.58e-071841247848d05afd5a2ef61fb8a09c0f5fa2a56fd5c160b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC3 NDN NDST3 NWD2 TBC1D4 KCNH2 UNC79

8.90e-071851247cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TCN1 SYNE1 SLCO4C1 KCNH2 PYGL KEL TOP2A

1.14e-061921247072281344d58e85c9a290750b488d0c101f75d54
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FRAS1 SYNE1 RNF213 TUBGCP5 VPS13A MACF1 LRBA

1.18e-0619312479337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

POLE MND1 ZRANB3 CCNB1 FANCI PARPBP TOP2A

1.18e-0619312474b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 GCNT3 MYO5B RHPN2 KCNJ16 PKHD1 AKT2

1.35e-0619712477e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FRAS1 SYNE1 RNF213 TUBGCP5 VPS13A MACF1 LRBA

1.35e-06197124757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellCOVID-19_Severe-immature_Neutrophil|COVID-19_Severe / Disease condition and Cell class

TCN1 APMAP SYNE1 POLE FANCI PYGL TOP2A

1.45e-061991247f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCellCOVID-19_Severe-immature_Neutrophil-|COVID-19_Severe / Disease condition and Cell class

TCN1 APMAP SYNE1 POLE FANCI PYGL TOP2A

1.45e-06199124742ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCellCOVID-19-COVID-19_Severe-Myeloid-immature_Neutrophil|COVID-19_Severe / Disease, condition lineage and cell class

TCN1 APMAP SYNE1 POLE SLCO4C1 PYGL TOP2A

1.50e-062001247cbe667eda1af222467df8bfa157aa22df488f133
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-T/NK_proliferative|Bac-SEP / Disease, condition lineage and cell class

FILIP1 MND1 STARD6 CCNB1 FANCI PARPBP TOP2A

1.50e-062001247a09b4e07b273880e94032b939ab191caaf6d656e
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SYNE1 RNF213 PKHD1 MACF1 LRBA TOP2A

2.18e-061351246ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

POLE MND1 CCNB1 FANCI PARPBP TOP2A

7.95e-061691246b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

POLE MND1 CCNB1 FANCI PARPBP TOP2A

9.39e-06174124684da9faff088d05233183b425385beb054c92d1b
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POLE RNF17 CCNB1 TBC1D4 PARPBP TOP2A

9.71e-06175124673f25bd54309aed1480ddc44bdab518b17e71f92
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A|E18.5-samps / Age Group, Lineage, Cell class and subclass

POLE RNF213 CCNB1 PARPBP KIT TOP2A

1.21e-051821246ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 MROH2A DNAH1 ARFGEF3 PKHD1 UNC79

1.29e-0518412462cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 MROH2A DNAH1 ARFGEF3 PKHD1 UNC79

1.29e-051841246ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 MROH2A DNAH1 ARFGEF3 PKHD1 UNC79

1.29e-0518412462b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MYO5B MROH2A HNF4A SLC1A2 ARFGEF3 PKHD1

1.29e-051841246fa4915b0498f3069fd5ef497286445528f75187e
ToppCellURO-Lymphocyte-T_NK-T_NK_proliferative|URO / Disease, Lineage and Cell Type

MND1 STARD6 CCNB1 FANCI PARPBP TOP2A

1.33e-0518512460ae9c646679c69a553eda670aef0e0495feb0286
ToppCellfacs-Brain_Non-Myeloid-Cerebellum|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC3 NDN NDST3 NWD2 TBC1D4 KCNH2

1.33e-051851246c083a4974590b9ed3ecafedd3e9cdebc5047fe39
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FILIP1 NDN AIF1L ZNF112 KCNH2 TAGLN

1.37e-05186124626458ff8cad5577de4306cffa0ca69eb26940e0d
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FILIP1 NDN AIF1L ZNF112 KCNH2 TAGLN

1.37e-051861246a71397efc68d2916ddc373d92cfd07be58033e1c
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MND1 KCNH2 PYGL KEL KIT TOP2A

1.37e-051861246722da08cd978249a19855fd3ec8ddda780c99d83
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ARFGEF1 RNF213 ZNF407 PPP1R10 MACF1 LRBA

1.46e-051881246ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TCN1 SYNE1 KCNH2 PYGL KEL TOP2A

1.46e-051881246557a0ac069a6ff4e687cac032f64170b9b247165
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CWF19L2 MYO5B WRN TUBGCP5 DDX18 TOP2A

1.46e-0518812460476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CYP4F8 MND1 CCNB1 KCNH2 FANCI TOP2A

1.46e-051881246f5102e8d95506c25c675094b86162a6a50087b64
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 TRPC3 MND1 ART3 CACNA1H TAGLN

1.55e-0519012461ab3f19f1ce9f58e5125135704d94655a2e330a0
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 TRPC3 MND1 ART3 CACNA1H TAGLN

1.69e-051931246b9e11cd0896c0868aab7faec4ab7ab4d4e4d1b47
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MND1 NDST3 FANCI TAGLN PARPBP TOP2A

1.69e-051931246bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MYO5B RHPN2 KCNJ16 PKHD1 LRBA

1.69e-05193124682e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MND1 NDST3 FANCI TAGLN PARPBP TOP2A

1.69e-051931246516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CWF19L2 LPAR4 TOGARAM2 SLC44A1 DDX18 TOP2A

1.74e-05194124640c6e17e9e48d4fa6da3a0a1066c4c6565a1e096
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MND1 NDST3 FANCI TAGLN PARPBP TOP2A

1.74e-051941246590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MYO5B SLCO4C1 KCNJ16 PKHD1 LRBA

1.74e-05194124693c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellControl-Lymphocyte-T_NK-T_NK_proliferative|Control / Disease, Lineage and Cell Type

AIF1L MND1 CCNB1 FANCI PARPBP TOP2A

1.74e-051941246844731b7943d1cfca819b7b89e4e62067bfa0230
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MYO5B AIF1L RHPN2 KCNJ16 PKHD1

1.74e-0519412465eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FILIP1 MYO5B SYNE1 ARFGEF3 LIPH LRBA

1.79e-0519512469406866f99555198a9be311fbd65751b70f35446
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SYNE1 RNF17 CYP46A1 TXNIP CNOT6L MACF1

1.85e-051961246ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 AIF1L LIPH KCNJ16 PKHD1 LRBA

1.85e-051961246c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

APMAP SYNE1 RNF213 TXNIP CNOT6L MACF1

1.85e-0519612460f3c7fd450aaa1f866b8558692534c0ea2a34e75
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

APMAP SYNE1 RNF213 TXNIP CNOT6L MACF1

1.85e-0519612464e1f8828413896ab8a4ec92a89d6789e8e37e05a
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CWF19L2 RFC1 CCNB1 PARPBP SNRPB2 TOP2A

1.90e-05197124641bdea47b9b1f6415a866a515d1535ea942fdede
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CWF19L2 SYNE1 RNF213 VPS13A CACNA1I LRBA

1.90e-051971246e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

APMAP SYNE1 RNF213 TXNIP SLCO4C1 MACF1

1.95e-0519812460e918e9db9b884f5328d438e90efe065e27266ee
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

MND1 CCNB1 FANCI PARPBP PSMD14 TOP2A

1.95e-051981246880f9817f5145f10f29fc05c5866090433532fe2
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

APMAP SYNE1 RNF213 TXNIP SLCO4C1 MACF1

1.95e-051981246ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

APMAP SYNE1 RNF213 TXNIP SLCO4C1 MACF1

1.95e-051981246fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

APMAP SYNE1 RNF213 TXNIP SLCO4C1 MACF1

1.95e-0519812461ef3a6bd681c223eed58300348adfef89df5563c
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

APMAP SYNE1 RNF213 TXNIP SLCO4C1 MACF1

2.01e-051991246e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellCOVID-19_Moderate-NK|World / disease group, cell group and cell class

APMAP SYNE1 TOGARAM2 RNF213 TXNIP SLCO4C1

2.01e-051991246c41b67b760831c7d5e19fabcc932a056dc560f93
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

APMAP SYNE1 RNF213 TXNIP SLCO4C1 MACF1

2.01e-0519912465f914962e2572b0c6372465b81b7496fa663d93c
ToppCellsevere-Lymphocytic-Prol._cells|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MND1 CCNB1 FANCI PARPBP PSMD14 TOP2A

2.01e-051991246b24315952b6ac6c8d2d3a7bd949a5b5392624d4e
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells-Neuroepithelial_cell|3m / Sample Type, Dataset, Time_group, and Cell type.

AIF1L MND1 CCNB1 FANCI PARPBP TOP2A

2.07e-0520012462938a029fa0478be561574ace91f95c4a528b2d4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells|3m / Sample Type, Dataset, Time_group, and Cell type.

AIF1L MND1 CCNB1 FANCI PARPBP TOP2A

2.07e-052001246cfe017b4a4d604a553d0a3df9659687f38e9a7af
ToppCellmild-T/NK_proliferative|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

POLE MND1 CCNB1 FANCI PARPBP TOP2A

2.07e-05200124625b4a1a33348e274bd4457efc0d6faa5421c3d31
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

POLE MND1 CCNB1 FANCI PARPBP TOP2A

2.07e-05200124604bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCellSepsis-URO-Lymphocyte-T/NK-T/NK_proliferative|URO / Disease, condition lineage and cell class

MND1 STARD6 CCNB1 FANCI PARPBP TOP2A

2.07e-052001246f277db6cc288a52a5426120c1067608700ee8ccc
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-NK_activated|COVID-19_Severe / Disease, condition lineage and cell class

APMAP SYNE1 RNF213 TXNIP SLCO4C1 MACF1

2.07e-0520012466a77f9643646bafc1157bf1fc1e4c614860ee642
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

APMAP SYNE1 RNF213 ADAR TXNIP MACF1

2.07e-0520012462281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

POLE MND1 CCNB1 FANCI PARPBP TOP2A

2.07e-052001246f6b5320cdfe640a71e6e2df26f30d42e64b1c921
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright|ICU-NoSEP / Disease, condition lineage and cell class

ZCCHC18 TUBGCP5 SLC44A1 ANKEF1 DOCK7 C12orf60

2.07e-052001246c2df917900872453ea17a39928e39d071a6d3339
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LPAR3 CYP46A1 NWD2 LIPH PKHD1

5.37e-0514512459b69bfdbf91ef197b4c483617aa67498d9d2cd79
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LPAR3 CYP46A1 NWD2 LIPH PKHD1

5.37e-05145124531af9fce1dcd7e8ae1604476598e099232017ee9
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LPAR3 CYP46A1 NWD2 LIPH PKHD1

5.37e-05145124576f0cde9acdc3ad5948c007dccf312665972c9e6
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

POLE CCNB1 FANCI PARPBP TOP2A

5.92e-051481245b9d3421c2eb8e748e9508c1cbd1cb4f96e23db5a
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4|Hippocampus / BrainAtlas - Mouse McCarroll V32

POLE CCNB1 FANCI PARPBP TOP2A

5.92e-0514812452a7671dc27afbdf6a92d976c5f2b728bd18dd609
ToppCelldroplet-Lung-nan-3m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPAR3 TTLL5 RNF17 TBC1D4 FANCI

6.71e-05152124577b319f594d5e4df29034bbf69c7490076f89dd3
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPAR4 SLC1A2 ZRANB3 FANCI KCNJ16

7.14e-0515412455ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CWF19L2 MND1 HNF4A TBC1D4 CACNA1I

7.36e-0515512457aba8ef53c9170ad8ed955c904c8991097ab1e32
ToppCell390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

MND1 CCNB1 FANCI KEL TOP2A

8.30e-0515912450fbfdb18b7ed4bde077add13f2b3636e144b254f
ToppCell367C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

GCNT3 MYO5B AIF1L ANKEF1 TOP2A

8.81e-051611245c61283c301a87bb802f6f8ce79c26067032dd7d9
ToppCell367C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

GCNT3 MYO5B AIF1L ANKEF1 TOP2A

8.81e-0516112459864d8b0929dacf4be7a4e97d2527ac3120ea264
ToppCell390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MND1 KCNH2 FANCI KEL TOP2A

9.33e-051631245aa5ea367f787c1543afb7eb80a801432e1c44011
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|390C / Donor, Lineage, Cell class and subclass (all cells)

MND1 CCNB1 FANCI PARPBP TOP2A

9.61e-051641245ad508f53009efdd1dae7abcdb5431387f3f7e7b2
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CYP4F8 MND1 CCNB1 KEL TOP2A

9.61e-051641245fb18b863152fb3109e2224c791c84c6371680a4e
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MND1 CCNB1 FANCI PARPBP TOP2A

9.89e-051651245a5c3af634d2698f9a01cf074791756b7669f9fff
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MND1 CCNB1 FANCI PARPBP TOP2A

1.02e-0416612452642544070564debe2deb2938d2c33997bf5ef02
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-7|TCGA-Thryoid / Sample_Type by Project: Shred V9

ACAD10 CYP46A1 ANKEF1 AKT2 KIT

1.05e-04167124501c42e555913b17e62846325cc17b3d8f92da1e1
ToppCellICU-NoSEP-Lymphocyte-T_NK-NK_CD56bright|ICU-NoSEP / Disease, Lineage and Cell Type

ZCCHC18 TUBGCP5 SLC44A1 ANKEF1 C12orf60

1.05e-041671245f4f188a8efca8cdd0ecfb857fe4538c10847eadd
ToppCellDividing_Macrophages-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

MND1 CCNB1 FANCI PARPBP TOP2A

1.11e-041691245eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP46A1 CCNB1 KCNJ16 PARPBP TOP2A

1.11e-041691245563c267edaade0e5df192ad953801ef9768d4270
ToppCellfacs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAD10 HNF4A SLC44A1 TBC1D4 NUP188

1.14e-041701245d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell10x5'-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T|Lung / Manually curated celltypes from each tissue

MND1 CCNB1 FANCI PARPBP TOP2A

1.17e-041711245976361f67dd725870e0513ae7a92f2dcaee17148
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SYNE1 RNF213 ZNF407 CNOT6L MACF1

1.17e-0417112452e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCCHC18 ACAD10 PUS10 DSEL SERPIND1

1.20e-04172124510a1d1838492b8ce6dea08844353b51571432c56
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCCHC18 ACAD10 PUS10 DSEL SERPIND1

1.20e-041721245d824e46c8040b0bb9235f9b8a2b35386b303caa0
ToppCellfacs-Marrow-B-cells-24m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 LPAR4 APMAP RHPN2 CACNA1H

1.20e-04172124565b8935a972bf00b7a10dc2d442128fc0ed78bcb
ToppCell10x5'-Lung-Lymphocytic_NK-Cycling_NK|Lung / Manually curated celltypes from each tissue

MND1 CCNB1 LIPH FANCI TOP2A

1.23e-041731245d815832f89f70662706620e3b03ebb1dabec0034
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN1 HNF4A PYGL SERPIND1 XPOT

1.30e-0417512455c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

MND1 ARFGEF3 RHPN2 LIPH TOP2A

1.30e-041751245fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MND1 CCNB1 FANCI PARPBP TOP2A

1.30e-041751245876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

MND1 ARFGEF3 RHPN2 LIPH TOP2A

1.30e-04175124536c140540497bbe1c5f08fac2d94f08cac18fabb
DiseaseColorectal Carcinoma

SYNE1 POLE WRN ARFGEF1 NDST3 RHPN2 PUS10 VPS13A PKHD1 VRTN DSEL SNRPB2 RAB5C

5.42e-0670211913C0009402
Diseasecancer (implicated_via_orthology)

POLE MACF1 AKT2 KIT RAB5A TOP2A RAB5C

1.11e-042681197DOID:162 (implicated_via_orthology)
DiseaseCerebellar Ataxia

SYNE1 RFC1

1.60e-0451192C0007758
Diseasecolorectal cancer (biomarker_via_orthology)

TXNIP AKT2

2.39e-0461192DOID:9256 (biomarker_via_orthology)
Diseasehypoglycemia (is_implicated_in)

HNF4A AKT2

4.44e-0481192DOID:9993 (is_implicated_in)
Diseasebody surface area

FILIP1 COPB1 ACAD10 DOCK5 KCNH2 PKHD1 MACF1 C12orf60 UNC79

1.21e-036431199EFO_0022196
Disease1-stearoyl-2-linoleoyl-GPI (18:0/18:2) measurement

MYO5B DOCK7

1.22e-03131192EFO_0800413
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

COPB1 HNF4A DNAH1 DOCK7 RAI1

1.52e-032061195EFO_0004612, EFO_0020947
DiseaseMalignant Neoplasms

WRN KCNH2 AKT2 KIT

1.83e-031281194C0006826
Diseasecarcinoma (implicated_via_orthology)

KIT RAB5A RAB5C

2.23e-03641193DOID:305 (implicated_via_orthology)
DiseaseIntellectual Disability

NDST1 SYNE1 SLC1A2 PREPL GTF3C3 MACF1 RAI1

2.29e-034471197C3714756
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

HNF4A NARS2 MACF1

2.54e-03671193EFO_0008595, EFO_0020946
DiseaseCholecystitis

HNF4A LRBA

2.64e-03191192HP_0001082
DiseaseDiGeorge syndrome (implicated_via_orthology)

DOCK1 NDST1

2.64e-03191192DOID:11198 (implicated_via_orthology)
Diseaseovulation

FANCI KDM4A

2.64e-03191192GO_0030728
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

HNF4A DNAH1 DOCK7 MACF1 RAI1

3.10e-032431195EFO_0004612, EFO_0020944
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

HNF4A DOCK7 MACF1 LRBA

3.24e-031501194EFO_0004611, EFO_0020947
DiseaseNasopharyngeal carcinoma

SYNE1 AKT2

3.53e-03221192C2931822

Protein segments in the cluster

PeptideGeneStartEntry
MINMKALAALKLIFN

BHLHB9

481

Q6PI77
MEVAVSKARAKVTMN

AKT2

136

P31751
RSAVLKLVMMFEGKA

AIF1L

116

Q9BQI0
GFKTEMAMLVTQARK

ADCK2

541

Q7Z695
AMSVEKIAAIKAKIM

CDC73

176

Q6P1J9
VLMAQALEKLFMQKL

BRDT

116

Q58F21
EQMAKTAKALMEAVS

ARFGEF1

916

Q9Y6D6
LAAEDFTIFKAMMVQ

CFAP36

101

Q96G28
EQMAKTAKALMEAVS

ARFGEF2

861

Q9Y6D5
VVMGATKLFLILAKM

AP4B1

251

Q9Y6B7
NKAAALDIAMIKMVA

ACAD10

986

Q6JQN1
SMEILAKAKADMTIV

ANKEF1

96

Q9NU02
IKRMIFKLFSQETVM

APMAP

341

Q9HDC9
MIESKKAATVVLMLN

ARMC3

21

Q5W041
KFLLILDTAQEMVMV

NWD2

1146

Q9ULI1
QLMEVKAMKLFDASR

NDST3

61

O95803
KLFGLQEAMKVAVDM

RAI1

1841

Q7Z5J4
VEQSFMTMAAEIKKR

RAB1A

161

P62820
MVSKMIIENFEALKS

RBM26

1

Q5T8P6
TSMNVNEIFMAIAKK

RAB5A

166

P20339
KTAMNVNEIFMAIAK

RAB5C

166

P51148
FMLTKDQERAIKAMT

RABEP1

466

Q15276
MAVFNQKSVSDMIKE

PARPBP

1

Q9NWS1
VKVSMMQTKGNFLAA

SERPIND1

321

P05546
VEFVVEKALSMFSKM

FANCI

191

Q9NVI1
FLDSKDTMKMAVVLV

LCNL1

11

Q6ZST4
KEKIREMMDSFQFLV

FRAS1

2521

Q86XX4
LIKSDAAMTVAVKML

KIT

611

P10721
MKGMKVEVLNSDAVL

L3MBTL2

211

Q969R5
KVLKMITVHMAVFVV

LPAR4

246

Q99677
AVIMFILNFEVVMEK

KCNH2

121

Q12809
MIEQIQFIKLFGMAK

HNF4A

351

P41235
MMEIFSETKDVFQLK

MND1

16

Q9BWT6
EEIQMFRKSLVKMFE

CWF19L2

731

Q2TBE0
KKQNSFVAEAMLLMA

COPB1

576

P53618
AKVMDMVQKFLGVTN

NDST1

786

P52848
DMVKISMDVFVRKFQ

KDM4A

311

O75164
AFLLMFIKQLVMKDS

LRBA

656

P50851
KLMKTVMTVLGAFVV

LPAR3

236

Q9UBY5
KEAIMKVLNLALMFA

TUBGCP5

951

Q96RT8
NMSKEDAMVEFVKLL

ACBD3

151

Q9H3P7
KVAMVLKEFIDQMLA

LIPH

126

Q8WWY8
MTLVEVLQKKLMAFT

POLE

2201

Q07864
LDMVKVMTFALQEGK

PTPDC1

171

A2A3K4
LKAIKEMGFTNMTEI

DDX18

191

Q9NVP1
KMLVNLMAENKAISF

OR5AP2

86

Q8NGF4
TAVKLMEKLNMFQGF

MACF1

2326

Q9UPN3
AINSKMFEVDMKIAA

PAPOLA

471

P51003
QSVFTRMAVMKALNK

PUS10

241

Q3MIT2
RVEMTVSKFMAIQKA

QTRT2

121

Q9H974
INTAKLKLVLFMDAM

DNAH1

2551

Q9P2D7
LLDQVKVVASKAQMM

EBLN1

221

P0CF75
KKMLQLVGVTAMFIA

CCNB1

241

P14635
LNVSQKMIEMFVRTK

BABAM1

121

Q9NWV8
METFIMFKNLIGKNV

DOCK1

966

Q14185
LMETFIMFKDLIGKN

DOCK5

986

Q9H7D0
VFNLHMILSDTVKMK

DOCK7

1646

Q96N67
VAKQDAAMKAMTILL

ADAR

556

P55265
AAMKAMTILLEEAKA

ADAR

561

P55265
QFAQMEVKVVMAKLL

CYP46A1

441

Q9Y6A2
MVDFFNILNEIVMKL

SLC1A2

266

P43004
KDFMKQVQTSGVLMV

ARFGEF3

766

Q5TH69
NVVFTSMFALEMILK

CACNA1I

676

Q9P0X4
QAFAMAEMKVVLALT

CYP4F11

471

Q9HBI6
QKFAMAEMKVVLALT

CYP4F8

471

P98187
FPIKSNAEMVQALKM

GCNT3

231

O95395
VLMEFVENSRKAMKE

SLC44A1

621

Q8WWI5
TMVDPAINLFFLKMK

WTAP

111

Q15007
TAIFVAEMMVKVVAL

CACNA1H

1336

O95180
VALKTMKMRGQAFVI

SNRPB2

41

P08579
KQAVVDVMEKTMFLL

DSEL

251

Q8IZU8
VKLVQTMMFLSEVKN

CNOT6

371

Q9ULM6
TMMFLSEVKNIIDKA

CNOT6

376

Q9ULM6
KQAFKSMVQKMIFSL

OR6C75

296

A6NL08
DVLAVMKNMLKSNFL

OR2AJ1

296

Q8NGZ0
AVDPVFQAKMLDMLK

PSMD14

86

O00487
QDICLKMAFMKSVVQ

MROH2A

816

A6NES4
KMAFMKSVVQVTKAI

MROH2A

821

A6NES4
AMRQFKKAVTDAIMS

SYVN1

251

Q86TM6
FNDIMTVAKEKMRKV

SYNE1

2821

Q8NF91
KMVNILMANTKFDAF

TOGARAM2

676

Q6ZUX3
LKSFTVMLVDERKNM

FILIP1

501

Q7Z7B0
RVEQIKGAMMSIAFK

RFC1

776

P35251
IEELFKATTMMVLSK

NARS2

276

Q96I59
QMLQLMVAKKAVDAE

SIKE1

111

Q9BRV8
AILATNKILVDMAKM

WRN

1176

Q14191
MNKILKMIVSFTIGF

PKHD1

621

P08F94
KMIVSFTIGFQNMVK

PKHD1

626

P08F94
MVFKQMEQVAQFLKA

TAGLN

86

Q01995
KMMLAQAQESVFEKI

RHPN2

281

Q8IUC4
EITKAIKRAQIMGFM

MRPS18C

106

Q9Y3D5
KLVMFVQTEMRGKLS

STARD6

166

P59095
VFVLEMVLNRETKKM

GTF3C3

121

Q9Y5Q9
EQMLKIFKEMQSVVD

C12orf60

61

Q5U649
KLIQTMMFVSEVKNI

CNOT6L

371

Q96LI5
MMFVSEVKNILEKAS

CNOT6L

376

Q96LI5
VEFLKMVNNKAVSMK

RNF17

596

Q9BXT8
MVNNKAVSMKVFREE

RNF17

601

Q9BXT8
TIAKNLALKENVFMM

RNF213

2741

Q63HN8
LEMLFKKNLFEMAIN

VPS11

361

Q9H270
MIKMNIDSIFIVLEA

VPS13A

1721

Q96RL7
KNLMKNAVFMCLVLS

SLCO4C1

376

Q6ZQN7
MTMAFKDLKLVNDQI

KCNJ16

231

Q9NPI9
SVFLSVMEKAQKMND

TCN1

356

P20061
VFSAFITVLQMKEMK

NUP188

1206

Q5SRE5
VMNATAALEFLKDMK

SLFN12

136

Q8IYM2
FTMKRNTKVIDLDMF

PREPL

341

Q4J6C6
KMMLTQAQESVFEKI

RHPN2P1

196

A8MT19
MEKIITQVFEMDISK

TBC1D4

1156

O60343
MNMFKEAVTFKDVAV

ZNF226

1

Q9NYT6
KEVFQIVNLSIMVKM

TOPAZ1

1181

Q8N9V7
FKMQSLDKDIVALMV

TOP2A

226

P11388
MTKFQEMVTFKDVAV

ZNF112

1

Q9UJU3
MAETKDAAQMLVTFK

ZNF550

1

Q7Z398
LVVKMAERNMKLFSG

ZCCHC18

36

P0CG32
NVEAIMLAVMKKLTY

XPOT

371

O43592
MTKFQEMVTFKDVAV

ZNF233

1

A6NK53
MASQERAQVAFKKMV

ZNF407

2066

Q9C0G0
LVMDMIATTKFKAQA

VRTN

641

Q9H8Y1
MVMFKKIKSFEVVFN

TXNIP

1

Q9H3M7
MAKMIIKLITSVADV

PYGL

616

P06737
ISKIFSLMKEARKMV

PPP1R10

31

Q96QC0
MMKSQGLVSFKDVAV

ZNF300

1

Q96RE9
LKIKASMISDMFTVV

TTLL5

381

Q6EMB2
TVKDIFKFMVLFIMV

TRPC3

561

Q13507
KMMLQNDSLKFLVFA

ZRANB3

331

Q5FWF4
TVHQLITVLMKFMAK

UNC79

1276

Q9P2D8
GKLFQMVTIDQLKEM

KEL

296

P23276
VIFMSIELNLKIMAD

NALCN

926

Q8IZF0
MLLATMILVDIFQVK

ART3

11

Q13508
LEKAAMDMTVFLKLQ

MYO5B

1136

Q9ULV0
TKMQIMEFLARVFKK

NDN

271

Q99608