Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	TPR	LONRF1 CDC16 ASPH LONRF2 FKBP4	4.57e-05	129	57	5	SM00028
Domain	TPR_repeat	LONRF1 CDC16 ASPH LONRF2 FKBP4	5.28e-05	133	57	5	IPR019734
Domain	TPR-contain_dom	LONRF1 CDC16 ASPH LONRF2 FKBP4	9.35e-05	150	57	5	IPR013026
Domain	LON	LONRF1 LONRF2	1.36e-04	6	57	2	SM00464
Domain	LON_N	LONRF1 LONRF2	1.36e-04	6	57	2	PS51787
Domain	LON_substr-bd_dom	LONRF1 LONRF2	1.36e-04	6	57	2	IPR003111
Domain	LON_substr_bdg	LONRF1 LONRF2	1.36e-04	6	57	2	PF02190
Domain	TPR_REGION	LONRF1 CDC16 ASPH LONRF2 FKBP4	1.46e-04	165	57	5	PS50293
Domain	TPR	LONRF1 CDC16 ASPH LONRF2 FKBP4	1.46e-04	165	57	5	PS50005
Domain	-	LONRF1 CDC16 ASPH LONRF2 FKBP4	4.18e-04	207	57	5	1.25.40.10
Domain	TPR-like_helical_dom	LONRF1 CDC16 ASPH LONRF2 FKBP4	7.15e-04	233	57	5	IPR011990
Domain	Methyltransf_11	METTL13 ECE2	1.07e-03	16	57	2	PF08241
Domain	Methyltransf_11	METTL13 ECE2	1.07e-03	16	57	2	IPR013216
Domain	PUA-like_domain	LONRF1 LONRF2	1.51e-03	19	57	2	IPR015947
Domain	TPR_1	CDC16 LONRF2 FKBP4	2.62e-03	90	57	3	PF00515
Domain	TPR_1	CDC16 LONRF2 FKBP4	2.62e-03	90	57	3	IPR001440
Domain	Znf-RING_LisH	LONRF1 LONRF2	4.82e-03	34	57	2	IPR027370
Domain	zf-RING_UBOX	LONRF1 LONRF2	4.82e-03	34	57	2	PF13445
Domain	EGF_CA	EYS FBN1 TENM2	6.16e-03	122	57	3	SM00179
Domain	EGF-like_Ca-bd_dom	EYS FBN1 TENM2	6.44e-03	124	57	3	IPR001881
Domain	Laminin_G_2	EYS COL11A1	6.63e-03	40	57	2	PF02210
Domain	SET	SETDB1 KMT5A	6.95e-03	41	57	2	PF00856
Domain	LamG	EYS COL11A1	7.97e-03	44	57	2	SM00282
Domain	SET	SETDB1 KMT5A	8.69e-03	46	57	2	SM00317
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	KBTBD3 COL11A1 MYL6 ACACA RBM12B KMT5A CDC16 HNRNPA3 SMC4 MGA ARHGAP21	5.03e-08	754	59	11	35906200
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	DST MYL6 ACACA ZC3H4 EIF2S1 RPS8 HNRNPA3 SMC4 LARP1 KPNA6 TUBA4A LAP3 FKBP4	5.15e-08	1149	59	13	35446349
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	FANCD2 METTL13 MYL6 ACACA EIF2S1 CDC16 RPS8 HNRNPA3 SMC4 LARP1 KPNA6 LAP3 FKBP4 SDAD1	8.32e-08	1425	59	14	30948266
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	DST MYL6 RBM12B EIF2S1 CDC16 RPS8 ASPH HNRNPA3 SMC4 LARP1 TUBA4A FKBP4 SDAD1	1.45e-07	1257	59	13	36526897
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	ARHGAP5 MYL6 ZC3H4 EIF2S1 RPS8 ASPH HNRNPA3 SMC4 LARP1 TUBA4A SDAD1	1.62e-07	847	59	11	35850772
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	FANCD2 METTL13 ACACA EIF2S1 RPS8 SMC4 KPNA6 TUBA4A LAP3 FKBP4	2.79e-07	704	59	10	29955894
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	DST RBM12B HNRNPA3 SMC4 LARP1 KPNA6 TUBA4A	1.07e-06	315	59	7	26777405
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	DST ACACA EIF2S1 RPS8 HNRNPA3 SMC4 LARP1 FKBP4	1.42e-06	477	59	8	31300519
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	MYL6 ACACA EIF2S1 RPS8 HNRNPA3 SMC4 PALS2 FKBP4	1.58e-06	484	59	8	31995728
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	METTL13 ZC3H4 EIF2S1 RPS8 ASPH HNRNPA3 SMC4 TUBA4A	1.63e-06	486	59	8	30940648
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	ZC3H4 EIF2S1 KMT5A RPS8 PLCL2 HNRNPA3 LARP1 KPNA6 ARHGAP21 SDAD1	3.16e-06	922	59	10	27609421
Pubmed	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.	PTPRC MYL6 EIF2S1 RPS8 PALS2 TUBA4A LAP3 FKBP4	4.94e-06	565	59	8	20458337
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	FANCD2 MYL6 ACACA EIF2S1 RPS8 SMC4 LARP1 KPNA6 USP48 TUBA4A LAP3 FKBP4	4.96e-06	1455	59	12	22863883
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	MYL6 ACACA RBM12B ZC3H4 EIF2S1 RPS8 HNRNPA3 LAP3 FKBP4 SDAD1	5.87e-06	989	59	10	36424410
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	DST RBM12B ZC3H4 EIF2S1 RPS8 HNRNPA3 SMC4 MGA TUBA4A FKBP4	7.95e-06	1024	59	10	24711643
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	SORT1 FANCD2 METTL13 ACACA MTG2 KPNA6 TUBA4A ARHGAP21	8.23e-06	606	59	8	36538041
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	DST MYL6 ACACA RPS8 HNRNPA3 LARP1 PALS2 SPAG17 FKBP4	8.30e-06	807	59	9	30575818
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	SORT1 METTL13 MYL6 ACACA EIF2S1 HNRNPA3 SMC4 LARP1 KPNA6 FKBP4 SDAD1	9.14e-06	1284	59	11	17353931
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	MYL6 EIF2S1 RPS8 ASPH HNRNPA3 LARP1 WDR89 SDAD1	9.16e-06	615	59	8	31048545
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	MYL6 EIF2S1 RPS8 HNRNPA3 SMC4 LARP1 MGA	9.71e-06	441	59	7	31239290
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	METTL13 DST MYL6 ACACA ASPH HNRNPA3 SMC4 LARP1 KPNA6 TUBA4A FKBP4	1.00e-05	1297	59	11	33545068
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	METTL13 MYL6 ACACA EIF2S1 RPS8 HNRNPA3 SMC4 LARP1 KPNA6 TUBA4A LAP3	1.17e-05	1318	59	11	30463901
Pubmed	EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3.	MYL6 ACACA EIF2S1 RPS8 HNRNPA3	1.19e-05	174	59	5	35031058
Pubmed	Functional specialization of beta-arrestin interactions revealed by proteomic analysis.	MYL6 ACACA RPS8 HNRNPA3 TUBA4A ARHGAP21	1.64e-05	317	59	6	17620599
Pubmed	A DNA pooling-based case-control study of myopia candidate genes COL11A1, COL18A1, FBN1, and PLOD1 in a Chinese population.	COL11A1 FBN1	1.69e-05	4	59	2	21527992
Pubmed	Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing.	SETDB1 MGA	1.69e-05	4	59	2	34857746
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	NUGGC ACACA ZC3H4 SMC4 KPNA6 ARHGAP21 SDAD1	2.09e-05	497	59	7	36774506
Pubmed	NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.	MYL6 RPS8 HNRNPA3 SMC4 CCDC180 TUBA4A	2.17e-05	333	59	6	32665550
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	MYL6 ACACA ZC3H4 EIF2S1 RPS8 ASPH HNRNPA3 SMC4 LARP1 KPNA6 TUBA4A	2.26e-05	1415	59	11	28515276
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	MYL6 ACACA RPS8 ASPH HNRNPA3 LARP1 SDAD1	2.26e-05	503	59	7	36217030
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYL6 ACACA ZC3H4 SMC4 LARP1	2.44e-05	202	59	5	33005030
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ARHGAP5 DST MYL6 EIF2S1 PRXL2B RPS8 HNRNPA3 KNDC1 LARP1 TUBA4A ARHGAP21	2.50e-05	1431	59	11	37142655
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	MYL6 EIF2S1 RPS8 ASPH HNRNPA3 LARP1 TUBA4A SDAD1	2.59e-05	711	59	8	33022573
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	MYL6 ZC3H4 EIF2S1 RPS8 ASPH HNRNPA3 LARP1 SDAD1	2.65e-05	713	59	8	29802200
Pubmed	The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors.	MYL6 RPS8 HNRNPA3 LARP1 PALS2 FKBP4	2.86e-05	350	59	6	26549023
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	MYL6 ZC3H4 RPS8 LARP1 KPNA6 ARHGAP21	3.40e-05	361	59	6	30344098
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	DST ACACA ZC3H4 SMC4 PWWP3B MGA	3.51e-05	363	59	6	14691545
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	MYL6 ACACA EIF2S1 RPS8 HNRNPA3 SMC4 LARP1 MGA TUBA4A FKBP4	4.30e-05	1247	59	10	27684187
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	METTL13 MYL6 ACACA EIF2S1 RPS8 HNRNPA3 SMC4 LARP1 KPNA6 TUBA4A	4.60e-05	1257	59	10	37317656
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	FANCD2 METTL13 CDC16 HNRNPA3 SMC4 USP48 TUBA4A	5.69e-05	582	59	7	20467437
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	ACACA EIF2S1 ASPH SMC4 LARP1 FKBP4	5.92e-05	399	59	6	37536630
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	MYL6 EIF2S1 RPS8 HNRNPA3 SMC4 TUBA4A LAP3 FKBP4	6.11e-05	803	59	8	36517590
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	MYL6 EIF2S1 RPS8 ASPH HNRNPA3 SMC4 LARP1 ARHGAP21	6.44e-05	809	59	8	32129710
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	MYL6 EIF2S1 RPS8 HNRNPA3 LARP1 KPNA6 SDAD1	7.26e-05	605	59	7	28977666
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	DST RBM12B RPS8 HNRNPA3 LARP1	7.80e-05	258	59	5	37794589
Pubmed	MYND domain specific interaction of the melanin-concentrating hormone receptor 1 interacting zinc-finger protein with alpha- and beta-tubulin.	RPS8 TUBA4A	7.87e-05	8	59	2	16039987
Pubmed	Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells.	FANCD2 PTPRC	7.87e-05	8	59	2	29323295
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ARHGAP5 DST ACACA PCDH19 PALS2 ARHGAP21	7.96e-05	421	59	6	36976175
Pubmed	Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.	MYL6 EIF2S1 RPS8 ASPH HNRNPA3 LARP1	7.96e-05	421	59	6	34650049
Pubmed	RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.	EIF2S1 RPS8 HNRNPA3 SMC4 TUBA4A SDAD1	8.38e-05	425	59	6	21081503
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	METTL13 DST ACACA EIF2S1 RPS8 ASPH HNRNPA3 SMC4 MGA TUBA4A	8.49e-05	1353	59	10	29467282
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	METTL13 MYL6 EIF2S1 RPS8 LARP1	8.69e-05	264	59	5	32814769
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	MYL6 ACACA EIF2S1 RPS8 SMC4 KPNA6 FKBP4	8.80e-05	624	59	7	33729478
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	ACACA EIF2S1 RPS8 HNRNPA3 SMC4 KPNA6 FKBP4	1.01e-04	638	59	7	33239621
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SETDB1 ACACA CDC16 LARP1 KPNA6 SDAD1	1.01e-04	440	59	6	34244565
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	FANCD2 SETDB1 METTL13 MYL6 ZC3H4 CDC16 PCDH19 KPNA6 MGA	1.04e-04	1116	59	9	31753913
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	FANCD2 MYL6 RBM12B RPS8 HNRNPA3 SMC4 TUBA4A	1.15e-04	652	59	7	31180492
Pubmed	Stromal-cell-derived factor-1/CXCL12-induced chemotaxis of a T cell line involves intracellular signaling through Cbl and Cbl-b and their regulation by Src kinases and CD45.	PTPRC FYB1	1.26e-04	10	59	2	16503409
Pubmed	TGFβ pathway is required for viable gestation of Fanconi anemia embryos.	FANCD2 PTPRC	1.26e-04	10	59	2	36441774
Pubmed	Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.	MYL6 RPS8 HNRNPA3 LARP1 PALS2 TUBA4A	1.35e-04	464	59	6	32457219
Pubmed	Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases.	MYL6 RPS8 ASPH HNRNPA3 LARP1	1.46e-04	295	59	5	26209609
Pubmed	RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.	ZC3H4 RPS8 LARP1 MGA	1.46e-04	156	59	4	26170170
Pubmed	Cell cycle-dependent palmitoylation of protocadherin 7 by ZDHHC5 promotes successful cytokinesis.	MYL6 EIF2S1 RPS8 FKBP4	1.57e-04	159	59	4	36762613
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	DST MYL6 ACACA ZC3H4 RPS8 LARP1 ARHGAP21 FKBP4	1.73e-04	934	59	8	33916271
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	EIF2S1 RPS8 HNRNPA3 LARP1 TUBA4A FKBP4	1.90e-04	494	59	6	26831064
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	METTL13 DST MYL6 EIF2S1 RPS8 HNRNPA3 SMC4 LARP1	1.93e-04	949	59	8	36574265
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	DST RBM12B EIF2S1 RPS8 HNRNPA3 LARP1 FKBP4	2.18e-04	723	59	7	34133714
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	MYL6 ZC3H4 EIF2S1 CDC16 RPS8 HNRNPA3 SMC4 LARP1	2.25e-04	971	59	8	33306668
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	COL11A1 ASPH HNRNPA3 TUBA4A ARHGAP21 FKBP4 SDAD1	2.35e-04	732	59	7	34732716
Pubmed	VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway.	EIF2S1 RPS8 ASPH TUBA4A FKBP4	2.42e-04	329	59	5	35562734
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ARHGAP5 DST ACACA SMC4 LARP1 PWWP3B LONRF2	2.42e-04	736	59	7	29676528
Pubmed	The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.	ACACA RPS8 HNRNPA3 LARP1 FKBP4	2.46e-04	330	59	5	32529326
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	EIF2S1 RPS8 HNRNPA3 SMC4 TUBA4A	2.82e-04	340	59	5	24332808
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RBM12B EIF2S1 RPS8 ASPH HNRNPA3 LARP1 SDAD1	2.92e-04	759	59	7	35915203
Pubmed	EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos.	NAA11 TENM2	2.93e-04	15	59	2	26576615
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ARHGAP5 SETDB1 FBN1 DST LONRF1 KPNA6 PALS2 ARHGAP21 ECE2	2.97e-04	1285	59	9	35914814
Pubmed	ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells.	EIF2S1 RPS8 HNRNPA3	2.99e-04	76	59	3	36380368
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	DST MYL6 RBM12B EIF2S1 RPS8 SMC4	3.00e-04	538	59	6	28524877
Pubmed	Nucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolus.	MYL6 HNRNPA3 FKBP4	3.10e-04	77	59	3	23166591
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	DST RPS8 ASPH SMC4 MGA FKBP4	3.27e-04	547	59	6	37267103
Pubmed	SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.	MYL6 RPS8 LARP1 MGA TUBA4A	3.34e-04	353	59	5	27545878
Pubmed	LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.	RPS8 SMC4 MGA	3.35e-04	79	59	3	26446488
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	DST MYL6 ACACA ZC3H4 RPS8 MGA ARHGAP21	3.36e-04	777	59	7	35844135
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	ZC3H4 RPS8 HNRNPA3 SMC4 LARP1 MGA	3.40e-04	551	59	6	34728620
Pubmed	Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors.	FANCD2 MYL6 HNRNPA3 USP48 MGA	3.61e-04	359	59	5	35559673
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	SORT1 FANCD2 ARHGAP5 PTPRC PLCL2 KPNA6 FKBP4 SDAD1	3.78e-04	1049	59	8	27880917
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	FANCD2 HNRNPA3 LARP1 KPNA6 SDAD1	3.85e-04	364	59	5	24778252
Pubmed	USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.	METTL13 MYL6 ACACA RPS8 HNRNPA3 TUBA4A	3.89e-04	565	59	6	33567341
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	FANCD2 MYL6 EIF2S1 CDC16 RPS8 HNRNPA3 LARP1 KPNA6 SDAD1	3.93e-04	1335	59	9	29229926
Pubmed	Interactomic analysis of REST/NRSF and implications of its functional links with the transcription suppressor TRIM28 during neuronal differentiation.	EIF2S1 RPS8 HNRNPA3 CCDC180	4.14e-04	205	59	4	27976729
Pubmed	USP25 deficiency promotes T cell dysfunction and transplant acceptance via mitochondrial dynamics.	MYL6 RPS8	4.25e-04	18	59	2	36822087
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DST MYL6 RBM12B ZC3H4 EIF2S1 RPS8 HNRNPA3 SDAD1	4.65e-04	1082	59	8	38697112
Pubmed	FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.	ACACA SMC4 USP48 SDAD1	4.70e-04	212	59	4	33462405
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	DST ACACA CDC16 PALS2	4.70e-04	212	59	4	33853758
Pubmed	Functional proteomics mapping of a human signaling pathway.	ARHGAP5 SETDB1 DST PTPRC PLCL2 MGA	4.93e-04	591	59	6	15231748
Pubmed	Identification of a hormone-regulated dynamic nuclear actin network associated with estrogen receptor alpha in human breast cancer cell nuclei.	MYL6 RPS8	5.27e-04	20	59	2	20308691
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	MYL6 EIF2S1 RPS8 ASPH HNRNPA3 LARP1	5.38e-04	601	59	6	33658012
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	DST MYL6 RPS8 HNRNPA3 KPNA6 TUBA4A FKBP4	5.51e-04	844	59	7	25963833
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	CDC16 HNRNPA3 SMC4 KPNA6 USP48	5.51e-04	394	59	5	27248496
Pubmed	The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.	SORT1 KBTBD3 MYL6 RPS8 HNRNPA3 PALS2	5.53e-04	604	59	6	37616343
Coexpression	ZHOU_TNF_SIGNALING_4HR	FBN1 MYL6 RPS8 TUBA4A	4.93e-06	50	59	4	M1520
Coexpression	GSE36009_UNSTIM_VS_LPS_STIM_NLRP10_KO_DC_DN	ACACA RPS8 SLFN12 WDR89 RINL FYB1	5.56e-06	198	59	6	M8768
Coexpression	GSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_UP	ARHGAP5 SOBP LARP1 PALS2 MGA LAP3	5.89e-06	200	59	6	M7613
Coexpression	MARTINEZ_RB1_TARGETS_DN	SORT1 COL11A1 NAA11 KMT5A RPS8 KPNA6 TENM2 TUBA4A	3.93e-05	569	59	8	M12701
Coexpression	MURARO_PANCREAS_BETA_CELL	ARHGAP5 DST SOBP PLCL2 LARP1 PALS2 LONRF2 USP48 TUBA4A FKBP4	4.51e-05	946	59	10	M39169
Coexpression	LIAN_LIPA_TARGETS_6M	DST SLFN12 FYB1 LILRB5	6.86e-05	97	59	4	MM1016
Coexpression	BUSSLINGER_GASTRIC_ISTHMUS_CELLS	DST MYL6 RPS8 SMC4 LARP1 ARHGAP21 FER1L6	7.40e-05	458	59	7	M40010
Coexpression	GSE41867_NAIVE_VS_DAY30_LCMV_ARMSTRONG_MEMORY_CD8_TCELL_DN	SETDB1 MTG2 LARP1 WDR89 ECE2	8.61e-05	199	59	5	M9504
Coexpression	MATSUDA_NATURAL_KILLER_DIFFERENTIATION	COL11A1 DST CLCA3P PRXL2B PALS2 FKBP4 SDAD1	1.07e-04	486	59	7	M18517
ToppCell	10x5'-Liver-Myeloid_Mac-Intestinal_macrophages\|Liver / Manually curated celltypes from each tissue	DST SOBP PCDH19 KNDC1 LILRB5	2.02e-06	156	59	5	9a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCell	facs-MAT-Fat-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC WDR89 RINL FYB1 TUBA4A	2.99e-06	169	59	5	3a18b4ad826e6ab9cbfd1d51a23a1b67c9a08596
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 SMC4 WDR89 FYB1	3.26e-06	172	59	5	25bf2551d698237bfd912c2ff067b1600dfb19ca
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 SMC4 WDR89 FYB1	3.36e-06	173	59	5	46dbc51270cc80d6e0b7118c53cec8516b1bb508
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 SMC4 WDR89 FYB1	3.55e-06	175	59	5	f7547eade69aa1d012db963adf59f36a309beae6
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 SMC4 WDR89 FYB1	3.65e-06	176	59	5	3bf8ef0afad8c96f814355ead5b993d58cd1ce35
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 SMC4 WDR89 FYB1	3.75e-06	177	59	5	0d6167c6a11c7dec0717ae7c8b4c45341585804f
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 SMC4 WDR89 FYB1	3.75e-06	177	59	5	81511383b010ab744ebc622c180f926d469194c1
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 SMC4 WDR89 FYB1	3.86e-06	178	59	5	a8d6aae3c35de6e7d1421cc48e58688adbdf16aa
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 SMC4 WDR89 FYB1	3.86e-06	178	59	5	61363c3365d3e191c47be1b2a35fa8afbfa64ff2
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 SMC4 WDR89 FYB1	3.96e-06	179	59	5	1309d41dbf286e9230fde6a7949e60c24d86766a
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 SMC4 WDR89 FYB1	3.96e-06	179	59	5	20cac7b3035a2bb0b09f58741617550f1f623fc9
ToppCell	droplet-Mammary_Gland-nan-18m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MYL6 ASPH TENM2 TUBA4A	5.30e-06	190	59	5	313ad9ec736e3da5968dc9e9bbdfe508d935b552
ToppCell	normal_Pleural_Fluid-T/NK_cells-Exhausted_CD8+_T\|normal_Pleural_Fluid / Location, Cell class and cell subclass	PTPRC MYL6 SMC4 FYB1 TUBA4A	5.87e-06	194	59	5	68a9e00c9e1a855eeebfc26c038652f3800758db
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FANCD2 PTPRC SMC4 WDR89	5.88e-05	159	59	4	e9c51e611ebd427bbe51e3e036c14122c36ea372
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RINL FYB1 TUBA4A	6.02e-05	160	59	4	741e3b3f4ec5c77752da54746451f332435226e3
ToppCell	facs-GAT-Fat-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC WDR89 RINL FYB1	6.94e-05	166	59	4	d22a08b415ef9e48398d69f3e45b04c33a085411
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC RINL FYB1 TUBA4A	7.11e-05	167	59	4	d72b08b3cbc34b30a11dcf512e472b64d1606ec1
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC RINL FYB1 TUBA4A	7.11e-05	167	59	4	22f7384ff2044898d7b0b01cb9d9a3cbaa93a9a3
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACACA RBM12B PLCL2 SMC4	7.27e-05	168	59	4	4c402a1613fcf0a6e4d9b9d5551812940e91ff32
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FANCD2 COL11A1 FBN1 TENM2	7.44e-05	169	59	4	335619507857383c3b0b507cdf05d786ed59e585
ToppCell	facs-SCAT-Fat-18m-Lymphocytic-T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC SMC4 RINL TUBA4A	7.44e-05	169	59	4	700a3a36c379872585204caa6a6cc269b036ae22
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FANCD2 PTPRC SLFN12 RINL	7.79e-05	171	59	4	6e7ade1d14a3ec4c566476aac3eb509bd2661e39
ToppCell	facs-Thymus-Flowthrough-24m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL6 RPS8 WDR89 RINL	7.79e-05	171	59	4	e2b72282244dee008e3b5d03667be9f26b7c2f6d
ToppCell	facs-Thymus-Flowthrough-24m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL6 RPS8 WDR89 RINL	7.79e-05	171	59	4	1064c20c37fae6cefb2eb4fa0628e4037a78179c
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC GARNL3 WDR89 FYB1	7.97e-05	172	59	4	3f784aed340b50ddbec3f7dc0a5279180d38a2bb
ToppCell	facs-Spleen-nan-24m-Lymphocytic-Cd3e_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMC4 WDR89 RINL FYB1	8.15e-05	173	59	4	f2eeff86e7dc7f4e3c36f775777d56685d7096cf
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 SMC4 WDR89	8.33e-05	174	59	4	76694cd8a1162047a9ee60521ce84201b4378a47
ToppCell	droplet-Bladder-nan-24m-Hematologic-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC RINL FYB1 CCDC180	8.71e-05	176	59	4	0089b50d607f4d2f18639fab0f3fc779227baa7a
ToppCell	facs-MAT-Fat-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC SMC4 RINL TUBA4A	8.71e-05	176	59	4	77c6103639acd0f3d6a2171c5f37a8083b6c2cf0
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC SMC4 RINL FYB1	8.90e-05	177	59	4	9d2d70d53b919fed3328812889a55e5e1a0759de
ToppCell	PND28-Immune\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 WDR89 FYB1	8.90e-05	177	59	4	087bcda36589e3554e6f2c170542a4be7833cfd2
ToppCell	facs-Liver-Non-hepatocytes-24m-Lymphocytic-mature_NK_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC WDR89 RINL FYB1	9.10e-05	178	59	4	291ffc52b824e4f59078147eb640ef34e24fb450
ToppCell	facs-GAT-Fat-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC RINL FYB1 TUBA4A	9.10e-05	178	59	4	44634ba10da34307d6217646b221ddf5d7a65fb0
ToppCell	Immune_cells-T_cells\|Immune_cells / Lineage and Cell class	PTPRC RPS8 WDR89 FYB1	9.10e-05	178	59	4	af420242277e2a4e2524002a2914b0538f79a134
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FANCD2 ARHGAP5 STAP2 PALS2	9.29e-05	179	59	4	5be883d7d0be3180bb9844e4a757f0dd247294e4
ToppCell	facs-MAT-Fat-24m-Lymphocytic-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC WDR89 FYB1 TUBA4A	9.50e-05	180	59	4	f3f7a610db750fcb84d746a5ea0d8b57f9b7d901
ToppCell	PND14-Immune\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 WDR89 FYB1	9.50e-05	180	59	4	1f8c383851d561b17d3a4e5791c4c9f05f58f024
ToppCell	facs-MAT-Fat-24m-Lymphocytic\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC WDR89 FYB1 TUBA4A	9.50e-05	180	59	4	bb2f1b254371924b2045e9e1a81b6dbf4f00dd6a
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS8 SMC4 WDR89	9.70e-05	181	59	4	5e1b784c6bd445593855751329ead0eecd5e1736
ToppCell	facs-Spleen-nan-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP5 DST RINL FYB1	9.91e-05	182	59	4	fbe5bdd642b86010dbef0a567b25c69c7335688f
ToppCell	facs-SCAT-Fat-3m-Lymphocytic-T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC SMC4 FYB1 TUBA4A	1.03e-04	184	59	4	cdacb61878e0824b8416bf365d89965797208359
ToppCell	droplet-Mammary_Gland-nan-3m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC RPS8 SMC4 FYB1	1.06e-04	185	59	4	02a2cbae9238c6c1e80b9a52a575e3b22f0eebb4
ToppCell	343B-Lymphocytic-CD4_T-cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	PTPRC RPS8 FYB1 TUBA4A	1.08e-04	186	59	4	f6743d1f1d57d9d9a4581a88f156078a1da46816
ToppCell	droplet-Mammary_Gland-nan-3m-Lymphocytic-T_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC RPS8 SMC4 FYB1	1.15e-04	189	59	4	e00938e90f0bb0bfe17b74ef601c09079e1c2b17
ToppCell	facs-Marrow-KLS-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC7 PALS2 LAP3 SDAD1	1.15e-04	189	59	4	b28a0e2d5a5f512f9b137b162b195bdc3d5ee9ba
ToppCell	droplet-Limb_Muscle-nan-3m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC RPS8 SMC4 FYB1	1.17e-04	190	59	4	d00fa8eda2454c5f9eddfb0e08913a68bb0bd8fc
ToppCell	facs-Thymus-Epithelium-24m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORT1 DST SOBP TENM2	1.19e-04	191	59	4	eec14997d2bfc7e6b5a601afc43a147f6b96d668
ToppCell	facs-Thymus-Epithelium-24m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORT1 DST SOBP TENM2	1.19e-04	191	59	4	1730ec5dc1cfd2f0cba7e21555641c7bce97e09d
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	PTPRC RPS8 FYB1 TUBA4A	1.19e-04	191	59	4	0583a0db58197af609ae251dcf882fc48cd6c897
ToppCell	Myeloid-Myeloid-B_(Activated_Macrophage)\|Myeloid / shred on cell class and cell subclass (v4)	SORT1 DST HNRNPA3 LAP3	1.19e-04	191	59	4	7bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PTPRC SMC4 FYB1 TUBA4A	1.19e-04	191	59	4	912e2d10d3423aa7f708fcf2b11da1845f12d7d3
ToppCell	droplet-Mammary_Gland-nan-3m-Lymphocytic-T_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC RPS8 SMC4 FYB1	1.19e-04	191	59	4	7943049e935c09cbda6f60ab3f09c4424a5f9d43
ToppCell	facs-Thymus-Epithelium-24m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORT1 DST SOBP TENM2	1.19e-04	191	59	4	4b77abc68bd72c64e7062f9527fe9d9605289ceb
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PTPRC SMC4 FYB1 TUBA4A	1.19e-04	191	59	4	77a2746b6d9c53b08d4405411c16fcc5a6c734ce
ToppCell	Severe-Lymphoid-Plasma\|Severe / Condition, Lineage, Cell class and cell subclass	NUGGC SMC4 USP48 TUBA4A	1.22e-04	192	59	4	8d26584c7897a2c77df9efe787e7c04d1e883df9
ToppCell	Severe-Lymphoid-Plasma-\|Severe / Condition, Lineage, Cell class and cell subclass	NUGGC SMC4 USP48 TUBA4A	1.22e-04	192	59	4	3a900d872da80b47104245440eb09b8c80b0b2b0
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL11A1 ACACA SOBP KNDC1	1.22e-04	192	59	4	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NUGGC PTPRC PLCL2 SMC4	1.24e-04	193	59	4	544de0988510cc57744710d7cafe07aa27a0b99d
ToppCell	ILEUM-inflamed-(1)_T_cell-(1)_TFH-like\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ARHGAP5 PTPRC RPS8 FYB1	1.24e-04	193	59	4	88cc740dd216ea80605b857c27914a8bc6ba6771
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORT1 PRXL2B PCDH19 TUBA4A	1.24e-04	193	59	4	55eab7d2574e9cc2ed8f08e0a7ca7cbf90fb5818
ToppCell	wk_15-18-Hematologic_Lymphocytic-T_&_ILC-Cycling_T\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PTPRC SMC4 FYB1 TUBA4A	1.24e-04	193	59	4	bec113472c40c0106a9427248cbcf54548797596
ToppCell	LAM-Lymphoid-T-cell\|Lymphoid / Condition, Lineage and Cell class	PTPRC RPS8 FYB1 TUBA4A	1.24e-04	193	59	4	0d9ceeb3c4d2bf5d13a29bf1b352cf2b70f3ed12
ToppCell	droplet-Mammary_Gland-nan-3m-Lymphocytic\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC RPS8 SMC4 FYB1	1.24e-04	193	59	4	11bb0c1e506f7f46c2bcbe864867070fb1ce9030
ToppCell	droplet-Mammary_Gland-nan-18m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL6 ASPH TENM2 TUBA4A	1.27e-04	194	59	4	a516839871c4e9683093a1c07b72c682f9ecbb3d
ToppCell	E12.5\|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EIF2S1 CDC16 HNRNPA3 FKBP4	1.27e-04	194	59	4	4b335e4da58de1cd94194dc4208ce83854e5e50a
ToppCell	normal_Lung-T/NK_cells-CD4+_Th\|normal_Lung / Location, Cell class and cell subclass	PTPRC RPS8 FYB1 TUBA4A	1.29e-04	195	59	4	d6c69f149f3d96fe83f920e38277dede102d04b5
ToppCell	(1)_Dll4_loss-of-function\|World / Stress and Cell class	PTPRC RPS8 SMC4 TUBA4A	1.29e-04	195	59	4	def4b2350e08a36ffddca71ea80ef611f2d437d9
ToppCell	(1)_Dll4_loss-of-function-(0)_LMPP_(LSK_cells)\|World / Stress and Cell class	PTPRC RPS8 SMC4 TUBA4A	1.29e-04	195	59	4	f11cf4b6855a26ff6ea572eebaad2aad6bb2434b
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NUGGC PTPRC FYB1 TUBA4A	1.32e-04	196	59	4	ac601d53e20ca2edd022764cf2c239461ec119c7
ToppCell	MS-CD4-exh_CD4\|MS / Condition, Cell_class and T cell subcluster	PTPRC MYL6 SMC4 FYB1	1.32e-04	196	59	4	d0217eccaa2cbf4ce9934e9d2e0c34a7f5c1a57e
ToppCell	367C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MYL6 SMC4 FYB1 TUBA4A	1.32e-04	196	59	4	e38036a5dbaed1488e01616bdc7678b28968470b
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NUGGC PTPRC FYB1 TUBA4A	1.32e-04	196	59	4	2d55f5a683e574873aee908da0b02b450d9340df
ToppCell	droplet-Tongue-nan-3m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORT1 PRXL2B PCDH19 TUBA4A	1.32e-04	196	59	4	159061fd0961b2cfb5941d403acc5b395dd0d3a0
ToppCell	droplet-Mammary_Gland-nan-18m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL6 ASPH TENM2 TUBA4A	1.32e-04	196	59	4	558324d7779463fd5cd438aee7d0f86be7366d3f
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NUGGC PTPRC FYB1 TUBA4A	1.32e-04	196	59	4	756e76440a92fa35ec8f6ad4900110ab202810cf
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NAA11 LONRF1 PCDH19 TENM2	1.34e-04	197	59	4	dfeb4a0eb4dfba90f4a3e6ba31e0ab0e4aba5849
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL11A1 FBN1 SOBP PWWP3B	1.34e-04	197	59	4	c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCell	distal-Hematologic-CD4+_Naive_T-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PTPRC RPS8 FYB1 TUBA4A	1.34e-04	197	59	4	bbb7283cbda60d3efe048a2b501f9bfa533190a6
ToppCell	distal-3-Hematologic-CD4+_Naive_T\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PTPRC RPS8 FYB1 TUBA4A	1.34e-04	197	59	4	9d2b8cc5a3398b41c25a21997314f44b2b429842
ToppCell	MS-CD4-naive_CD4\|MS / Condition, Cell_class and T cell subcluster	RPS8 SMC4 FYB1 TUBA4A	1.34e-04	197	59	4	eb0d4849de4ca374bd9c1e138d4f2b9c19227b15
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / Treatment groups by lineage, cell group, cell type	SORT1 METTL13 KMT5A SMC4	1.34e-04	197	59	4	038fd92750257d43d5e980fd06d77742b543f11a
ToppCell	distal-Hematologic-CD4+_Naive_T\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PTPRC RPS8 FYB1 TUBA4A	1.37e-04	198	59	4	17ea354c1feea9905adfe06a1800bd7c871b2dd7
ToppCell	distal-Hematologic-CD4+_Memory/Effector_T-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NUGGC PTPRC FYB1 TUBA4A	1.37e-04	198	59	4	7a89635f3567b4d2e6cd684c47be2e015d72a357
ToppCell	IIH-CD4-naive_CD4\|IIH / Condition, Cell_class and T cell subcluster	RPS8 SMC4 FYB1 TUBA4A	1.37e-04	198	59	4	85414b283bbcdbf3393ab1b4302ef0e21c7a8181
ToppCell	21-Trachea-Immune-Hematopoietic,_T_Cells\|Trachea / Age, Tissue, Lineage and Cell class	PTPRC RPS8 FYB1 TUBA4A	1.37e-04	198	59	4	da32693a9833ffeced87fe6ec91f076648005f6d
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL11A1 FBN1 LONRF2 TENM2	1.37e-04	198	59	4	7a0c4dbc8c99968d42af00a718f4fedc544599ec
ToppCell	HSPCs\|World / Lineage and Cell class	EIF2S1 SMC4 TUBA4A FKBP4	1.40e-04	199	59	4	df1ffc416c6946f1ba182f242a50ee41a571d565
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell-(7)_ACKR1+_endothelial_cells\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FBN1 MYL6 RPS8 ASPH	1.40e-04	199	59	4	6df0e8ec701c763b1cae5cabcc9e3c25cdbfe4bf
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_DC2\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PTPRC EIF2S1 RPS8 FYB1	1.40e-04	199	59	4	64b320a9e4e65071cff77980dbff7e06526819b3
ToppCell	LPS_only-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-T-cells\|LPS_only / Treatment groups by lineage, cell group, cell type	PTPRC SMC4 FYB1 TUBA4A	1.40e-04	199	59	4	bd7f03bef4660c347da5f16db34d91d563908448
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PTPRC RPS8 FYB1 TUBA4A	1.40e-04	199	59	4	c142c2e5874b811991905ed46f9c5a67a811e8a0
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL11A1 FBN1 PWWP3B TENM2	1.40e-04	199	59	4	45c3b853900d8c3d5965117d904e3714100138bc
ToppCell	Int-URO\|World / Disease, Lineage and Cell Type	PTPRC MYL6 FYB1 LAP3	1.40e-04	199	59	4	792a8717c048854952ca26cdc58d325f2ece6c1a
ToppCell	distal-2-Hematologic-CD4+_Memory/Effector_T\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NUGGC PTPRC FYB1 TUBA4A	1.40e-04	199	59	4	037623d279f4f5120be06bae230e69b8d5222af4
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Radial_glial\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ARHGAP5 COL11A1 ASPH TUBA4A	1.42e-04	200	59	4	4477591efada4007bab1f689017e3ac285267d29
ToppCell	medial-Hematologic-CD8+_Naive_T\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NUGGC PTPRC FYB1 TUBA4A	1.42e-04	200	59	4	2de8fae1011c57270170fb200a8897add7fe9bfc
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal\|3m / Sample Type, Dataset, Time_group, and Cell type.	PTPRC SPAG17 TUBA4A ECE2	1.42e-04	200	59	4	ce012d738cbec1afdd6af0e10e94b2b6c17b036e
ToppCell	medial-2-Hematologic-CD8+_Naive_T\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NUGGC PTPRC FYB1 TUBA4A	1.42e-04	200	59	4	5e5c1c5b6d2fcfad7b93488b976a68f5be1435e5
ToppCell	Sigmoid-Dendritic_cell-cycling_DCs\|Dendritic_cell / Region, Cell class and subclass	ASPH SMC4 LILRB5 SDAD1	1.42e-04	200	59	4	372fe9018481a4e9ac6ab3af43705a48238c4376
Disease	autosomal dominant nonsyndromic deafness (is_implicated_in)	COL11A1 USP48	2.06e-04	11	58	2	DOID:0050564 (is_implicated_in)
Disease	pulse pressure measurement, social deprivation	FBN1 PLCL2	3.40e-04	14	58	2	EFO_0005763, EFO_0009696
Disease	osteoarthritis, hip	COL11A1 PLCL2 SPAG17	7.99e-04	92	58	3	EFO_1000786
Disease	unipolar depression, neuroticism measurement	EYS ARHGAP21	1.02e-03	24	58	2	EFO_0003761, EFO_0007660
Disease	age at menarche	COL11A1 DST RBM12B ZC3H4 TENM2 ECE2	1.08e-03	594	58	6	EFO_0004703

Protein segments in the cluster

Peptide	Gene	Start	Entry
EEEYIEEEEYLGKEG	ERICH6B	106	Q5W0A0
EEEEYLGKEGYLEEE	ERICH6B	111	Q5W0A0
LGKEGYLEEEEYLGK	ERICH6B	116	Q5W0A0
EEHLEEEEYLGKEGY	ERICH6B	131	Q5W0A0
EEEYLGKEGYLEKED	ERICH6B	136	Q5W0A0
YEKGYVKDVDDGLQA	ACACA	286	Q13085
DLVDYEEVLGKLGIY	ASPH	76	Q12797
GEEEDKEEGLEEIYY	CCDC180	801	Q9P1Z9
AEDDIYLLYDDKGVG	RBM12B	426	Q8IXT5
DKIYILGGDYAPDEI	KBTBD3	551	Q8NAB2
AAEGAVLGLYEYDDL	LAP3	151	P28838
TGALDYEEGHVYELD	PCDH19	301	Q8TAB3
KAEDYDEGENGRVTY	PCDH19	591	Q8TAB3
EETVKDYEAGQLYGL	LARP1	976	Q6PKG0
YCGLIEEAYGLDKIE	KPNA6	466	O60684
ELIKLEGYNVYDGDE	EYS	3146	Q5T1H1
DIAAGEELLYDYGDR	KMT5A	366	Q9NQR1
IKEEPLDDYDYELGE	MGA	381	Q8IWI9
VADIFDRDGDGYIDY	DST	7241	Q03001
DLGDYYVVFVKSDDG	FNDC7	311	Q5VTL7
EVACYGYEGIDAVKE	EIF2S1	196	P05198
DGYCTADIEYLEDVK	LONRF1	656	Q17RB8
DLLVDGDLGEYDFYE	COL11A1	371	P12107
ILEPKELDDVYDGYE	ECE2	551	P0DPD6
YEDYVEGLRVFDKEG	MYL6	86	P60660
NDGEIYDDIADGCIY	FYB1	766	O15117
SDVGYDIFVLYKEGE	LILRB5	246	O75023
DGYNTADIEYLEDEK	LONRF2	626	Q1L5Z9
EADIKAGKYLEHGEY	PALS2	396	Q9NZW5
YIGDSEAYIGADIKD	CDC16	526	Q13042
LLEDEGYKGFVGCEY	HYI	236	Q5T013
EDKYDKDYLSGELGD	FBN1	2846	P35555
LYEEDGKDLDFYDFE	KNDC1	11	Q76NI1
EGAIVEVALEGYYKD	FKBP4	166	Q02790
GDYVIEDVQGDDKRY	METTL13	396	Q8N6R0
DGYVLEGKELEFYLR	RPS8	186	P62241
DVYEDGEAGLLLCYN	GARNL3	706	Q5VVW2
KALYGLEEYDTQDGI	FANCD2	681	Q9BXW9
ELYDSDAVGKPEYLG	FER1L6	901	Q2WGJ9
FLDGDYFAGELYLDE	PRXL2B	81	Q8TBF2
DPEDYEDGCILGYKE	SORT1	626	Q99523
LDEDYEKVLGYVEAD	STAP2	246	Q9UGK3
DGLYKELADVGSEYK	NUGGC	741	Q68CJ6
AVDGLDYEAAEAKYL	PWWP3B	651	Q5H9M0
VLDDDYIGDEFIGQY	PLCL2	831	Q9UPR0
RLGDVQYKIDDDGYL	TENM2	2256	Q9NT68
KVLYDAYAEAELGQG	MTG2	386	Q9H4K7
DEYALDGKIYELDLR	ARHGAP5	621	Q13017
EYGELDAKDYIPGAE	SDAD1	466	Q9NVU7
EKGDYYLEEEEEGDE	SPAG17	1086	Q6Q759
YDGEESCYIIDAKLE	SETDB1	1201	Q15047
ADVIVADLYLKYGDD	CLCA3P	101	Q9Y6N3
ELLDPDELRGEAGYY	RINL	481	Q6ZS11
LSYIAEDEDGKIVGY	NAA11	41	Q9BSU3
YGYDKVELKDGEDIE	SOBP	46	A7XYQ1
YGRLGDLGAIDEKYD	SMC4	616	Q9NTJ3
EDYSYTKDGIGLDLE	SLFN12	66	Q8IYM2
GGIKEDTEEYNLRDY	HNRNPA3	131	P51991
LLGDAEDYGHYEELP	ZC3H4	711	Q9UPT8
EDALDYLIGGLYHEK	WDR89	271	Q96FK6
SYDEGLDDYREDAKL	ARHGAP21	881	Q5T5U3
DYMLGDGIQEEKDYE	USP48	126	Q86UV5
EGLEAENKVDVYGYV	PTPRC	871	P08575
AALEKDYEEVGIDSY	TUBA4A	426	P68366