Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

MYLK NEK10 DTYMK SPEG OBSCN FGFRL1 PFKL CDK10 POLR3A RNASEL PARP16 UHMK1 POLL MAP2K6 EPHA5

5.73e-059389915GO:0016772
GeneOntologyCellularComponentextracellular matrix

LRRC3C VWC2 MXRA5 CILP WNT2 MATN2 WNT7A LAMA1 TF F12 SVEP1 BMP1 FCGBP HMCN2

3.24e-0665610114GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LRRC3C VWC2 MXRA5 CILP WNT2 MATN2 WNT7A LAMA1 TF F12 SVEP1 BMP1 FCGBP HMCN2

3.35e-0665810114GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

VWC2 MXRA5 CILP WNT2 MATN2 LAMA1 TF F12 BMP1 HMCN2

2.46e-0453010110GO:0062023
GeneOntologyCellularComponentbasement membrane

VWC2 MATN2 LAMA1 TF HMCN2

3.16e-041221015GO:0005604
GeneOntologyCellularComponentendocytic vesicle

WNT7A ATG14 CUBN DYSF TF LRP1 RAB7B LTF

5.51e-043841018GO:0030139
GeneOntologyCellularComponenttransferase complex

UBR1 LZTR1 GTF2A1L MTF2 NEK10 SPTLC2 ATG14 PFKL BCOR CDK10 POLR3A SF3B3 ACTL6B

7.41e-0496310113GO:1990234
HumanPhenoLimited knee flexion/extension

FLNC MYOT DYSF

1.31e-057383HP:0005085
HumanPhenoLimited knee flexion

FLNC MYOT DYSF

1.31e-057383HP:0006389
HumanPhenoFinger flexor weakness

FLNC DYSF

5.42e-052382HP:0031177
DomainIGc2

LILRA3 MXRA5 MYOT MYLK CILP SPEG VSIG4 MYOM3 OBSCN MCAM FGFRL1 HMCN2

3.72e-092359812SM00408
DomainIg_sub2

LILRA3 MXRA5 MYOT MYLK CILP SPEG VSIG4 MYOM3 OBSCN MCAM FGFRL1 HMCN2

3.72e-092359812IPR003598
DomainIg_I-set

MXRA5 MYOT MYLK CILP SPEG VSIG4 MYOM3 OBSCN FGFRL1 HMCN2

6.04e-081909810IPR013098
DomainI-set

MXRA5 MYOT MYLK CILP SPEG VSIG4 MYOM3 OBSCN FGFRL1 HMCN2

6.04e-081909810PF07679
DomainGrowth_fac_rcpt_

MATN2 LAMA1 CUBN SVEP1 BMP1 FAT1 HMCN2 LRP1 EPHA5

1.31e-07156989IPR009030
DomainEGF_CA

MATN2 CUBN F12 SVEP1 BMP1 FAT1 HMCN2 LRP1

2.53e-07122988SM00179
DomainEGF-like_Ca-bd_dom

MATN2 CUBN F12 SVEP1 BMP1 FAT1 HMCN2 LRP1

2.87e-07124988IPR001881
DomainEGF_CA

MATN2 CUBN SVEP1 BMP1 FAT1 HMCN2 LRP1

3.38e-0786987PF07645
DomainEGF-like_dom

MATN2 LAMA1 CUBN F12 SVEP1 BMP1 FAT1 FCGBP HMCN2 LRP1

7.42e-072499810IPR000742
DomainASX_HYDROXYL

MATN2 CUBN SVEP1 BMP1 FAT1 HMCN2 LRP1

9.48e-07100987PS00010
DomainEGF-like_CS

MATN2 LAMA1 CUBN F12 SVEP1 BMP1 FAT1 HMCN2 LRP1 EPHA5

1.14e-062619810IPR013032
DomainEGF_2

MATN2 LAMA1 CUBN F12 SVEP1 BMP1 FAT1 HMCN2 LRP1 EPHA5

1.31e-062659810PS01186
DomainEGF-type_Asp/Asn_hydroxyl_site

MATN2 CUBN SVEP1 BMP1 FAT1 HMCN2 LRP1

1.41e-06106987IPR000152
DomainIG

LILRA3 MXRA5 MYOT MYLK CILP SPEG VSIG4 MYOM3 OBSCN MCAM FGFRL1 HMCN2

2.08e-064219812SM00409
DomainIg_sub

LILRA3 MXRA5 MYOT MYLK CILP SPEG VSIG4 MYOM3 OBSCN MCAM FGFRL1 HMCN2

2.08e-064219812IPR003599
DomainIg-like_fold

FLNC LILRA3 MXRA5 MYOT MYLK CILP SPEG VSIG4 MYOM3 OBSCN MCAM FGFRL1 IFNGR1 HMCN2 EPHA5

3.92e-067069815IPR013783
DomainEGF

MATN2 LAMA1 CUBN F12 SVEP1 BMP1 FAT1 FCGBP LRP1

4.04e-06235989SM00181
DomainEGF

MATN2 CUBN F12 SVEP1 BMP1 FAT1 LRP1

4.47e-06126987PF00008
Domain-

FLNC LILRA3 MXRA5 MYOT MYLK CILP SPEG VSIG4 MYOM3 OBSCN MCAM FGFRL1 IFNGR1 EPHA5

9.14e-0666398142.60.40.10
DomainIG_LIKE

LILRA3 MXRA5 MYOT MYLK CILP SPEG VSIG4 MYOM3 OBSCN MCAM FGFRL1 HMCN2

9.97e-064919812PS50835
DomainTUDOR

ARID4B ARID4A MTF2 SETDB1

1.14e-0527984SM00333
DomainEGF_Ca-bd_CS

CUBN SVEP1 BMP1 FAT1 HMCN2 LRP1

1.20e-0597986IPR018097
DomainIg-like_dom

LILRA3 MXRA5 MYOT MYLK CILP SPEG VSIG4 MYOM3 OBSCN MCAM FGFRL1 HMCN2

1.27e-055039812IPR007110
DomainEGF_CA

CUBN SVEP1 BMP1 FAT1 HMCN2 LRP1

1.35e-0599986PS01187
DomainTudor

ARID4B ARID4A MTF2 SETDB1

1.76e-0530984IPR002999
DomainRBB1NT

ARID4B ARID4A

2.73e-052982PF08169
DomainRBB1NT

ARID4B ARID4A

2.73e-052982IPR012603
DomainEGF_3

MATN2 CUBN F12 SVEP1 BMP1 FAT1 HMCN2 LRP1

3.31e-05235988PS50026
DomainEGF_1

LAMA1 CUBN F12 SVEP1 BMP1 FAT1 HMCN2 LRP1

5.90e-05255988PS00022
DomainTransferrin

TF LTF

8.15e-053982PF00405
DomainTransferrin

TF LTF

8.15e-053982IPR016357
DomainTRANSFERRIN_LIKE_4

TF LTF

8.15e-053982PS51408
DomainTRANSFERRIN_LIKE_1

TF LTF

8.15e-053982PS00205
DomainTRANSFERRIN_LIKE_2

TF LTF

8.15e-053982PS00206
DomainTRANSFERRIN_LIKE_3

TF LTF

8.15e-053982PS00207
DomainTransferrin_Fe_BS

TF LTF

8.15e-053982IPR018195
DomainTR_FER

TF LTF

8.15e-053982SM00094
DomainTransferrin-like_dom

TF LTF

8.15e-053982IPR001156
DomainFN3_dom

FLNC MYLK SPEG MYOM3 OBSCN IFNGR1 EPHA5

1.16e-04209987IPR003961
DomainTudor-knot

ARID4B ARID4A

4.03e-046982PF11717
DomainAA_TRANSFER_CLASS_2

SPTLC2 ALAS2

4.03e-046982PS00599
DomainTudor-knot

ARID4B ARID4A

4.03e-046982IPR025995
DomainAminotrans_II_pyridoxalP_BS

SPTLC2 ALAS2

4.03e-046982IPR001917
DomainFN3

FLNC MYLK SPEG MYOM3 OBSCN EPHA5

4.31e-04185986SM00060
Domainig

LILRA3 VSIG4 MYOM3 OBSCN MCAM FGFRL1

4.97e-04190986PF00047
DomainImmunoglobulin

LILRA3 VSIG4 MYOM3 OBSCN MCAM FGFRL1

4.97e-04190986IPR013151
DomainPre-SET

SETMAR SETDB1

5.63e-047982PF05033
DomainPreSET

SETMAR SETDB1

5.63e-047982SM00468
DomainPre-SET_dom

SETMAR SETDB1

5.63e-047982IPR007728
DomainPRE_SET

SETMAR SETDB1

5.63e-047982PS50867
DomainS_TKc

MYLK NEK10 SPEG OBSCN CDK10 RNASEL UHMK1 MAP2K6

6.03e-04359988SM00220
DomainPROTEIN_KINASE_ATP

MYLK NEK10 SPEG OBSCN CDK10 RNASEL UHMK1 MAP2K6 EPHA5

6.88e-04459989PS00107
Domain-

SPTLC2 CTH ALAS2

8.12e-04359833.90.1150.10
DomainPyrdxlP-dep_Trfase_major_sub2

SPTLC2 CTH ALAS2

8.82e-0436983IPR015422
DomainPkinase

MYLK NEK10 SPEG OBSCN CDK10 RNASEL UHMK1 MAP2K6

8.88e-04381988PF00069
DomainVWC

VWC2 FCGBP VWC2L

1.03e-0338983SM00214
DomainProt_kinase_dom

MYLK NEK10 SPEG OBSCN CDK10 RNASEL UHMK1 MAP2K6 EPHA5

1.08e-03489989IPR000719
Domain-

SPTLC2 CTH ALAS2

1.12e-03399833.40.640.10
DomainPROTEIN_KINASE_DOM

MYLK NEK10 SPEG OBSCN CDK10 RNASEL UHMK1 MAP2K6 EPHA5

1.14e-03493989PS50011
DomainPyrdxlP-dep_Trfase

SPTLC2 CTH ALAS2

1.29e-0341983IPR015424
DomainPyrdxlP-dep_Trfase_major_sub1

SPTLC2 CTH ALAS2

1.29e-0341983IPR015421
DomainVWF_dom

VWC2 FCGBP VWC2L

1.39e-0342983IPR001007
DomainMBD

SETDB1 MBD5

1.45e-0311982SM00391
DomainMBD

SETDB1 MBD5

1.45e-0311982PS50982
DomainMethyl_CpG_DNA-bd

SETDB1 MBD5

1.45e-0311982IPR001739
DomainMBD

SETDB1 MBD5

1.45e-0311982PF01429
DomainDNA-bd_dom

SETDB1 MBD5

1.45e-0311982IPR016177
Domainfn3

MYLK SPEG MYOM3 OBSCN EPHA5

1.64e-03162985PF00041
DomainKinase-like_dom

MYLK NEK10 SPEG OBSCN CDK10 RNASEL UHMK1 MAP2K6 EPHA5

2.18e-03542989IPR011009
Domain-

ARID4B ARID4A

2.74e-03159821.10.150.60
DomainBRIGHT

ARID4B ARID4A

2.74e-0315982SM00501
DomainARID_dom

ARID4B ARID4A

2.74e-0315982IPR001606
DomainARID

ARID4B ARID4A

2.74e-0315982PS51011
DomainARID

ARID4B ARID4A

2.74e-0315982PF01388
DomainPost-SET_dom

SETMAR SETDB1

3.12e-0316982IPR003616
DomainPostSET

SETMAR SETDB1

3.12e-0316982SM00508
DomainPOST_SET

SETMAR SETDB1

3.12e-0316982PS50868
DomainAminotran_1_2

SPTLC2 ALAS2

3.52e-0317982PF00155
DomainAminotransferase_I/II

SPTLC2 ALAS2

3.52e-0317982IPR004839
DomainProtein_kinase_ATP_BS

MYLK NEK10 SPEG OBSCN CDK10 MAP2K6 EPHA5

3.82e-03379987IPR017441
DomainFN3

MYLK SPEG MYOM3 OBSCN EPHA5

3.98e-03199985PS50853
DomainWnt

WNT2 WNT7A

4.40e-0319982IPR005817
DomainWNT1

WNT2 WNT7A

4.40e-0319982PS00246
DomainWnt_CS

WNT2 WNT7A

4.40e-0319982IPR018161
Domainwnt

WNT2 WNT7A

4.40e-0319982PF00110
DomainWNT1

WNT2 WNT7A

4.40e-0319982SM00097
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLNC LZTR1 CEBPB SPEG MYOM3 OBSCN GEMIN5 FGFRL1 DYSF FAT1 TMEM132A KBTBD11 POLL MBD5

3.86e-0611051011435748872
Pubmed

Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance.

LRP1 LTF

8.35e-06210121464627
Pubmed

Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes.

ARID4B ARID4A

8.35e-062101218728284
Pubmed

"Dilysine trigger" in transferrins probed by mutagenesis of lactoferrin: crystal structures of the R210G, R210E, and R210L mutants of human lactoferrin.

TF LTF

8.35e-062101212450380
Pubmed

Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia.

CUBN TF

8.35e-062101211606717
Pubmed

A novel FLNC frameshift and an OBSCN variant in a family with distal muscular dystrophy.

FLNC OBSCN

8.35e-062101229073160
Pubmed

Lactotransferrin is the major estrogen inducible protein of mouse uterine secretions.

TF LTF

8.35e-06210123611056
Pubmed

Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases.

SPEG OBSCN

8.35e-062101215185077
Pubmed

Clearance of Neutrophils From ICH-Affected Brain by Macrophages Is Beneficial and Is Assisted by Lactoferrin and CD91.

LRP1 LTF

8.35e-062101238063014
Pubmed

Multivalent metal-induced iron acquisition from transferrin and lactoferrin by myeloid cells.

TF LTF

8.35e-062101212165535
Pubmed

PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation.

MYLK ITGA4

8.35e-062101235365657
Pubmed

Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.

FLNC MYOT

2.50e-053101211038172
Pubmed

Role of lactoferrin and its receptors on biliary epithelium.

LRP1 LTF

2.50e-053101229550924
Pubmed

Identification of a lactoferrin-derived peptide possessing binding activity to hepatitis C virus E2 envelope protein.

TF LTF

2.50e-053101212522210
Pubmed

Transcriptional changes in dendritic cells underlying allergen specific induced tolerance in a mouse model.

CEBPB IFNGR1

2.50e-053101235181694
Pubmed

Apoptosis inducing factor deficiency causes reduced mitofusion 1 expression and patterned Purkinje cell degeneration.

MFN1 AIFM1

2.50e-053101220974255
Pubmed

Modulation of cell adhesion and motility in the immune system by Myo1f.

MYO1F LTF

2.50e-053101217023661
Pubmed

Downregulation of ARID4A and ARID4B promote tumor progression and directly regulated by microRNA-30d in patient with prostate cancer.

ARID4B ARID4A

2.50e-053101229797600
Pubmed

Differential involvement of sarcomeric proteins in myofibrillar myopathies: a morphological and immunohistochemical study.

FLNC MYOT

2.50e-053101219151983
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

MXRA5 PFKL CUBN DYSF TF LAP3 FAT1 FCGBP SLC12A1 HEBP1 CTH MBD5

3.97e-0510161011219056867
Pubmed

ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways.

ARID4B ARID4A

4.99e-054101223487765
Pubmed

Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain.

ARID4B ARID4A

4.99e-054101217043311
Pubmed

Role of C/EBP-β, p38 MAPK, and MKK6 in IL-1β-mediated C3 gene regulation in astrocytes.

CEBPB MAP2K6

4.99e-054101221308746
Pubmed

Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.

MYLK OBSCN

4.99e-054101226147384
Pubmed

Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans.

LILRA3 RNASEL

4.99e-054101224891332
Pubmed

VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells.

MCAM ITGA4

4.99e-054101225135296
Pubmed

The integrin ligand SVEP1 regulates GPCR-mediated vasoconstriction via integrins α9β1 and α4β1.

ITGA4 SVEP1

4.99e-054101235802072
Pubmed

The expanding role of MBD genes in autism: identification of a MECP2 duplication and novel alterations in MBD5, MBD6, and SETDB1.

SETDB1 MBD5

4.99e-054101223055267
Pubmed

Functional proteomics mapping of a human signaling pathway.

FLNC MTF2 MAN1C1 MCAM UNC45A PFKL SVEP1 SETDB1 LRP1

5.80e-05591101915231748
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DHX40 LAMA1 BCOR SF3B3 LTF HNRNPR

6.47e-05234101636243803
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

GEMIN5 RCC1 PFKL TF LAP3 SF3B3 AIFM1 CTH LTF

7.11e-05607101939147351
Pubmed

Human immunodeficiency virus-1 Tat protein increases the number of inhibitory synapses between hippocampal neurons in culture.

GRIN2A LRP1

8.30e-055101224198379
Pubmed

Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR.

SETMAR SETDB1

8.30e-055101218498648
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

LZTR1 ARID4B ARRDC4 BCOR TF SETDB1 FAT1 SF3B3 HMCN2 LRP1 ACTL6B GARRE1

9.70e-0511161011231753913
Pubmed

Two forms of human Inscuteable-related protein that links Par3 to the Pins homologues LGN and AGS3.

PARD3B GPSM2

1.24e-046101216458856
Pubmed

Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies.

MYOM3 DYSF

1.24e-046101226060189
Pubmed

Phosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in Striatum.

GRIN2A PDE10A

1.24e-046101225762721
Pubmed

Yeast two-hybrid screening for proteins that interact with alpha1-adrenergic receptors.

FLNC BMP1

1.24e-046101215525470
Pubmed

A novel neural-specific BMP antagonist, Brorin-like, of the Chordin family.

VWC2 VWC2L

1.24e-046101219852960
Pubmed

Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue.

WNT2 WNT7A

1.24e-04610128168088
Pubmed

Fungal dissemination is limited by liver macrophage filtration of the blood.

VSIG4 IFNGR1

1.24e-046101231594939
Pubmed

ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex.

SETDB1 MYO1F

1.24e-046101227732843
Pubmed

Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice.

WNT2 WNT7A GRIN2A

1.33e-0434101328069946
Pubmed

Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea.

WNT2 WNT7A GPSM2

1.45e-0435101332907846
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

UBR1 FLNC SPTLC2 DHX40 GEMIN5 RCC1 UNC45A PFKL POLR3A SF3B3 AIFM1 LTF HNRNPR

1.50e-0413531011329467282
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

UBR1 FLNC SPTLC2 DTYMK GEMIN5 PFKL LAP3 SETDB1 FCGBP SF3B3 AIFM1 HEBP1 LRP1

1.66e-0413671011332687490
Pubmed

Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures.

GRIN2A LRP1

1.74e-047101223267846
Pubmed

Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death.

GRIN2A LRP1

1.74e-047101219036954
Pubmed

Low density lipoprotein receptor-related protein 1 (LRP1) modulates N-methyl-D-aspartate (NMDA) receptor-dependent intracellular signaling and NMDA-induced regulation of postsynaptic protein complexes.

GRIN2A LRP1

1.74e-047101223760271
Pubmed

The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.

FLNC MYOT

1.74e-047101216076904
Pubmed

Cooperation between TGF-beta and Wnt pathways during chondrocyte and adipocyte differentiation of human marrow stromal cells.

WNT2 WNT7A

1.74e-047101215040835
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

FLNC MCAM ITGA4 LAP3 FAT1 LRP1

1.90e-04285101621423176
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FLNC CEBPB ARID4B ARID4A RCC1 PFKL RNASEL LRP1 CTH HSPA14

2.00e-048571011025609649
Pubmed

Identification and characterization of three new components of the mSin3A corepressor complex.

ARID4B ARID4A

2.31e-048101212724404
Pubmed

HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes.

GRIN2A LRP1

2.31e-048101217360663
Pubmed

Myofibrillar Myopathy – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

FLNC MYOT

2.31e-048101220301672
Pubmed

Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development.

WNT2 WNT7A

2.31e-04810122279700
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

CILP MAN1C1 CUBN DYSF TF LAP3 F12 FCGBP SLC12A1 TMEM132A LTF

2.83e-0410701011123533145
Pubmed

Sensory inputs control the integration of neurogliaform interneurons into cortical circuits.

GRIN2A BHLHE22

2.97e-049101225664912
Pubmed

Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea.

WNT2 WNT7A

2.97e-049101212702652
Pubmed

Expression of laminin alpha1, alpha2, alpha4, and alpha5 chains, fibronectin, and tenascin-C in skeletal muscle of dystrophic 129ReJ dy/dy mice.

LAMA1 ITGA4

2.97e-04910129882526
Pubmed

Fgf10 is essential for limb and lung formation.

WNT2 WNT7A

2.97e-04910129916808
Pubmed

Identification of the ligands of protein interaction domains through a functional approach.

CUBN LRP1

2.97e-049101217124247
Pubmed

A new nomenclature for int-1 and related genes: the Wnt gene family.

WNT2 WNT7A

2.97e-04910121846319
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

VWC2 MXRA5 LAMA1 MYOM3 OBSCN PFKL AIFM1 CFAP57 HNRNPR

3.00e-04736101929676528
Pubmed

Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds.

WNT2 WNT7A

3.70e-041010128275860
Pubmed

Nomenclature of the ARID family of DNA-binding proteins.

ARID4B ARID4A

3.70e-0410101215922553
Pubmed

Expression patterns of Wnt genes during development of an anterior part of the chicken eye.

WNT2 WNT7A

3.70e-0410101216258938
Pubmed

Mechanisms of Wnt signaling in development.

WNT2 WNT7A

3.70e-041010129891778
Pubmed

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease.

DHX40 RCC1 CDK10 SF3B3 AIFM1 MBD5 MAP2K6

4.15e-04463101727503909
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

UNC45A PFKL FAT1 AIFM1

4.25e-04120101427320910
Pubmed

Ephrin-A5 and EphA5 interaction induces synaptogenesis during early hippocampal development.

GRIN2A EPHA5

4.51e-0411101220824214
Pubmed

Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis.

ARID4B ARID4A

4.51e-0411101226258622
Pubmed

Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice.

CEBPB MATN2 HSPA14

5.29e-0454101319228596
Pubmed

Dysregulated cell signalling and reduced satellite cell potential in ageing muscle.

WNT2 WNT7A

5.41e-0412101231647919
Pubmed

Genome-wide association study implicates PARD3B-based AIDS restriction.

PARD3B LTF

5.41e-0412101221502085
Pubmed

Matrilin-2 interacts with itself and with other extracellular matrix proteins.

MATN2 LAMA1

5.41e-0412101212180907
Pubmed

Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1.

FCGBP AIFM1 MAP2K6

5.89e-0456101320706999
Pubmed

Temporal-Spatial Establishment of Initial Niche for the Primary Spermatogonial Stem Cell Formation Is Determined by an ARID4B Regulatory Network.

ARID4B ARID4A

6.38e-0413101228207192
Pubmed

Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice.

WNT7A LRP1

6.38e-0413101216207730
Pubmed

Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation.

FLNC MYOT

7.43e-0414101233742095
Pubmed

The DNA sequence and biological annotation of human chromosome 1.

ARID4B MAN1C1 OBSCN SETDB1 KCNC4 UHMK1 ALDH4A1 CTH CFAP57 HNRNPR

8.44e-0410311011016710414
Pubmed

Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity.

GRIN2A TF

8.55e-0415101226880306
Pubmed

Expression and estradiol regulation of Wnt genes in the mouse blastocyst identify a candidate pathway for embryo-maternal signaling at implantation.

WNT2 WNT7A

8.55e-0415101215044261
Pubmed

Expression patterns of Wnt genes in mouse gut development.

WNT2 WNT7A

8.55e-0415101211429295
Pubmed

Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.

ARID4B ARID4A PFKL

8.71e-0464101322865885
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

CILP MATN2 MCAM HMCN2

8.87e-04146101427068509
Pubmed

Molecular genetic studies of Wnt signaling in the mouse.

WNT2 WNT7A

9.76e-0416101210585256
Pubmed

Dual role of Fam208a during zygotic cleavage and early embryonic development.

SETDB1 GPSM2

9.76e-0416101234216590
Pubmed

The Wnts.

WNT2 WNT7A

9.76e-041610129889131
Pubmed

Sp6 and Sp8 transcription factors control AER formation and dorsal-ventral patterning in limb development.

WNT7A LAMA1

9.76e-0416101225166858
Pubmed

A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta.

WNT2 ITGA4

9.76e-0416101223610556
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

ARID4B ARID4A RCC1 SF3B3

9.81e-04150101428242625
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

UBR1 DTYMK PFKL POLR3A SF3B3 HNRNPR

9.90e-04390101617643375
Pubmed

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.

MCAM GEMIN5 SF3B3 AIFM1 PARP16 ATP11A

1.02e-03392101633144569
Pubmed

Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.

FLNC WNT7A BMP1 ALAS2

1.03e-03152101411044609
Pubmed

Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected men.

ARRDC4 GPSM2

1.10e-0317101221897333
Pubmed

Conserved and Divergent Features of Human and Mouse Kidney Organogenesis.

CUBN SLC12A1

1.10e-0317101229449453
Pubmed

C/EBPbeta, when expressed from the C/ebpalpha gene locus, can functionally replace C/EBPalpha in liver but not in adipose tissue.

CEBPB TF

1.10e-0317101210982846
Pubmed

Wnt family proteins are secreted and associated with the cell surface.

WNT2 WNT7A

1.10e-031710128167409
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MXRA5 MYOT MYLK SPEG MYOM3 OBSCN SIGLEC16 FGFRL1 HMCN2

1.48e-08161729593
GeneFamilyTransferrins

TF LTF

4.68e-053722908
GeneFamilyImmunoglobulin like domain containing

MXRA5 CILP VSIG4 MYOM3 MCAM HMCN2

1.19e-04193726594
GeneFamilyZinc fingers CXXC-type|Methyl-CpG binding domain containing

SETDB1 MBD5

8.40e-04117221025
GeneFamilyAT-rich interaction domain containing

ARID4B ARID4A

1.59e-0315722418
GeneFamilyWnt family|Endogenous ligands

WNT2 WNT7A

2.56e-0319722360
GeneFamilyFibronectin type III domain containing

MYLK MYOM3 OBSCN EPHA5

3.81e-03160724555
CoexpressionLIM_MAMMARY_STEM_CELL_UP

FLNC MYLK MATN2 LAMA1 MCAM FGFRL1 UNC45A BCOR SVEP1 BMP1 LRP1

2.01e-064799911M2573
CoexpressionLIM_MAMMARY_STEM_CELL_UP

FLNC MYLK MATN2 LAMA1 MCAM FGFRL1 UNC45A BCOR SVEP1 BMP1 LRP1

2.18e-064839911MM1082
CoexpressionGSE3982_EOSINOPHIL_VS_NEUTROPHIL_DN

LILRA3 SPTLC2 DYSF HEBP1 TMEM132A MAP2K6 GARRE1

9.78e-06196997M5405
CoexpressionRHEIN_ALL_GLUCOCORTICOID_THERAPY_UP

CEBPB MFN1 IFNGR1 ALAS2 LTF

1.04e-0576995M12784
CoexpressionPOOLA_INVASIVE_BREAST_CANCER_DN

MYLK MATN2 TF CDK10 ALDH4A1 LTF

1.16e-05133996M6767
CoexpressionNABA_MATRISOME

VWC2 MXRA5 CILP WNT2 MATN2 WNT7A LAMA1 F12 SVEP1 BMP1 HMCN2 CLEC2D VWC2L PSPN

3.11e-0510269914M5889
CoexpressionFORTSCHEGGER_PHF8_TARGETS_DN

UBR1 RGMB MYLK SPEG MATN2 OBSCN DYSF SF3B3 UHMK1 RAB7B ATP11A HNRNPR

3.98e-057839912M2488
CoexpressionBLUM_RESPONSE_TO_SALIRASIB_DN

SETMAR MYLK MTF2 DTYMK MATN2 GPSM2 HSPA14 HNRNPR

4.63e-05341998M2879
CoexpressionBOQUEST_STEM_CELL_UP

MXRA5 CEBPB CILP MAN1C1 SVEP1 FAT1 LRP1

6.11e-05261997M1834
CoexpressionHATADA_METHYLATED_IN_LUNG_CANCER_UP

VWC2 GTF2A1L GRIN2A BCOR DYSF TF KCNC4 EPHA5

9.32e-05377998M19508
CoexpressionNABA_ECM_GLYCOPROTEINS

MXRA5 CILP MATN2 LAMA1 SVEP1 HMCN2

1.02e-04196996M3008
CoexpressionNABA_MATRISOME

VWC2 CILP WNT2 MATN2 WNT7A LAMA1 F12 SVEP1 BMP1 HMCN2 CLEC2D VWC2L PSPN

1.08e-0410089913MM17056
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

MXRA5 MYLK MATN2 LAMA1 BMP1 LRP1

1.14e-04200996M5930
CoexpressionGSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP

UBR1 ARID4A CDK10 MFN1 POLR3A ATG4D

1.14e-04200996M6035
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

MTF2 MATN2 WNT7A GEMIN5 PARD3B PFKL ITGA4 PDE10A SVEP1 RNASEL BHLHE22 LRP1 ZFP62 HNRNPR

1.43e-058019614gudmap_developingGonad_e14.5_ epididymis_1000
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RGMB MYLK SPEG MATN2 LAMA1 MCAM FAT1

3.37e-071971017f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEBPB NEK10 MATN2 CUBN HEBP1 LRP1

1.64e-0615810166811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEBPB MYLK WNT2 SVEP1 IFNGR1 LRP1

3.72e-06182101619c5e3a9d9b3728303b682102e276adfe93aa759
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEBPB MYLK WNT2 SVEP1 IFNGR1 LRP1

3.96e-061841016924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK WNT2 PDE10A SVEP1 LRP1 GPSM2

4.91e-061911016b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXD2 VWC2 CILP PDE10A SVEP1 FAT1

4.91e-061911016b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CEBPB LAMA1 PDE10A DYSF HMCN2 LTF

5.52e-061951016d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CEBPB LAMA1 PDE10A DYSF HMCN2 LTF

5.52e-06195101619853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FLNC MXRA5 CILP MATN2 FAT1 HMCN2

5.69e-06196101624d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellFibroblasts-DKK3+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FLNC MXRA5 CILP MATN2 FAT1 HMCN2

6.03e-0619810164f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC MYLK SPEG MCAM GRIN2A DYSF

6.03e-061981016c12e7511628db819a52959bb68580e27c00c2e41
ToppCell(5)_Fibroblast-E|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

MXRA5 CILP ARID4A MATN2 SVEP1 LRP1

6.39e-06200101675e5ecb05e965e24d569aa2ef5cdf740b1528c06
ToppCelldroplet-Liver-Npc-21m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETMAR AIFM1 HEBP1 GPSM2 CTH

1.87e-0514310150cd332c128710291a39957d3da22953352f5c382
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FOXD2 CUBN ZNF792 LTF EPHA5

3.21e-051601015bb1bb3673059768c0ea0160d29fff127f3a4ecb4
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FOXD2 CUBN ZNF792 LTF EPHA5

3.21e-05160101576f49b8b4450fa8acd36326bfa36a5d1f4bd95fb
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEBPB NEK10 CUBN HEBP1 LRP1

3.41e-051621015d712bc31840ad1523e3dbf884acbb428a8995001
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG4 IFNGR1 MYO1F LRP1 RAB7B

3.62e-051641015e19fc6ba049336ab989a3a968bdbefd567971d73
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG4 IFNGR1 MYO1F LRP1 RAB7B

3.62e-051641015d6526551d0b183c3ef027ba3dbfddeac03fd93bb
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG4 IFNGR1 MYO1F LRP1 RAB7B

3.62e-051641015eba25e4d65ca66b5192a7a4d11423f3fa0956828
ToppCellfacs-Kidney-nan-24m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXD2 SVEP1 FAT1 ALAS2 EPHA5

3.72e-0516510154cdd80580d5638fd649280ba3893251c2f898f3f
ToppCellfacs-Kidney-nan-24m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXD2 SVEP1 FAT1 ALAS2 EPHA5

3.72e-051651015c746bb22ef52d7f7fa6ee9c37ae6bbe0ccce718e
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPEG WNT7A VSIG4 TAGLN3 RAB7B

3.72e-0516510156dda1c7fd812792bd2e4fb1a7ccb82a3552b0a3b
ToppCelldroplet-Kidney-nan-24m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPB ITGA4 IFNGR1 MYO1F LRP1

3.94e-0516710152ee1660be117e20f24557522345572d11cbee813
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

MXRA5 CILP BMP1 BHLHE22 LTF

4.06e-051681015aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCelldroplet-Spleen-SPLEEN|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPB HEBP1 GPSM2 ALAS2 LTF

4.54e-051721015d32731a56e113ff0ef7167b23959d69baf2068f9
ToppCelldroplet-Spleen-SPLEEN-30m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPB HEBP1 GPSM2 ALAS2 LTF

4.54e-05172101502cc4a9fb7902c572cee37ba828749db4913ee87
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC CEBPB MYLK SPEG WNT7A

4.66e-0517310153001dd39244ef0a5a475d569a78f4ae427a55db6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC CEBPB MYLK SPEG WNT7A

4.66e-051731015c88883fb2a33e21d4201aa393674aa3f2ad780c9
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEBPB ITGA4 HEBP1 MYO1F LRP1

4.66e-0517310157713716ec95932b2fac177ce4cfec027b4754cef
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC MYOT CUBN ALAS2 LTF

4.66e-05173101566f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC MYOT CUBN ALAS2 LTF

4.66e-051731015649b08a409095592cccf31883be69c754411280d
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

VWC2 MCAM ITGA4 FAT1 KCNC4

4.79e-051741015015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLNC MYOT MYOM3 OBSCN PDE10A

5.06e-0517610159df7a124ebafb0087da0cda133a394275d7bed81
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

MYLK SPEG MCAM BMP1 FAT1

5.48e-051791015a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEBPB MYLK WNT2 MATN2 SVEP1

5.48e-051791015b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK MYOM3 MCAM FAT1 BHLHE22

5.78e-051811015429df38438d5a7ff490c9ede34b69e2970c7ded2
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK MYOM3 MCAM FAT1 BHLHE22

5.78e-051811015395cf5aa2d89b05328ab516b8c89401020b6d830
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPB WNT2 MATN2 SVEP1 RAB7B

5.78e-051811015c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

MXRA5 MYLK CILP WNT2 SVEP1

5.78e-051811015bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCellP28-Mesenchymal-mesenchymal_fibroblast|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEBPB WNT2 SVEP1 IFNGR1 LRP1

5.78e-051811015091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

CEBPB MYLK WNT2 SVEP1 LRP1

5.93e-051821015ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEBPB ARRDC4 VSIG4 LAP3 LRP1

5.93e-0518210154234d0cc57b5266a5e03133c75c7918abe48465e
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CILP MATN2 HMCN2 LRP1 RAB7B

5.93e-051821015e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CEBPB VSIG4 IFNGR1 FCGBP MYO1F

5.93e-051821015c6b3762ccec326f057819f75fa7fac0145fb7d54
ToppCellP28-Mesenchymal|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEBPB MYLK WNT2 SVEP1 LRP1

5.93e-05182101569f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPTLC2 VSIG4 LAP3 IFNGR1 FCGBP

6.25e-05184101597ae5ffecf90df42cc8eea2a247ca589f35a4783
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CEBPB DYSF TF MYO1F EPHA5

6.25e-0518410157ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FLNC MATN2 BMP1 FAT1 TMEM132A

6.41e-0518510150094f9baddb20214d2a2c166f1637d1a9cf1169a
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

CILP MATN2 SVEP1 HMCN2 GPSM2

6.41e-051851015fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP MATN2 SVEP1 BMP1 LRP1

6.41e-051851015eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCellP15-Mesenchymal-mesenchymal_fibroblast|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEBPB MYLK WNT2 IFNGR1 LRP1

6.41e-05185101546460e74cc613df9043f5404e7342aa13cc34873
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP MATN2 SVEP1 BMP1 LRP1

6.41e-051851015f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP MATN2 SVEP1 BMP1 LRP1

6.41e-051851015ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

MCAM CUBN DYSF HMCN2 TMEM132A

6.57e-0518610152e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

MCAM CUBN DYSF HMCN2 TMEM132A

6.57e-051861015c3449e54454009973818fc1101933c6f0168258c
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

UBR1 MYLK ARID4B ARID4A PARD3B

6.57e-05186101503db813598b67b1e08f759758a1c2023396921fa
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEBPB MYLK WNT2 IFNGR1 LRP1

6.57e-05186101588e6246172d816806a498a5c1f38e699f2f5d7c2
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWC2 FLNC SPEG FAT1 KCNC4

6.74e-051871015218c9b4f28499389c43005d9626af2ac01066027
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MXRA5 CEBPB CILP MATN2 SVEP1

6.74e-0518710156f47a80e612b320f571210483e62ff5db2a8ea43
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWC2 FLNC SPEG FAT1 KCNC4

6.74e-051871015c7ac4b328efc2ebb72f71154661914193ff402ca
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CILP WNT2 SVEP1 BHLHE22 LRP1

6.91e-051881015c32d023a69b6da79687ff8fa7485e7499db57046
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWC2 FLNC SPEG FAT1 KCNC4

6.91e-05188101561f010c165826b434ca3d27553d4c9e13d2c0c51
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RGMB MXRA5 PDE10A BMP1 FAT1

6.91e-051881015ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CEBPB SPTLC2 VSIG4 IFNGR1 FCGBP

6.91e-0518810153f47395db7e6159fc95810545bad4b6e028464c5
ToppCelldroplet-Lung-nan-18m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWC2 FLNC SPEG FAT1 KCNC4

6.91e-0518810157553ef7de3575af4cf34704b405b551c1af8eb83
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNC MYLK SPEG MCAM HMCN2

6.91e-051881015c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellfacs-MAT-Fat-3m|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 BMP1 ATP11A LTF GARRE1

6.91e-0518810157da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNC MYLK SPEG MCAM FAT1

6.91e-0518810154d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CILP WNT2 SVEP1 BHLHE22 LRP1

6.91e-0518810151cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCell(2)_Fibroblasts-(20)_Fibro-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

FLNC WNT2 HMCN2 LRP1 RAB7B

6.91e-051881015409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCellfacs-Skin-Telogen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN1C1 PFKL IFNGR1 FCGBP CFAP57

6.91e-0518810158cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCellfacs-Thymus-Epithelium-3m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK C16orf46 BMP1 FAT1 BHLHE22

7.09e-0518910151db5dd1ef2a65251af2d5696622d1dd9c4ae2b55
ToppCellfacs-Thymus-Epithelium-3m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK C16orf46 BMP1 FAT1 BHLHE22

7.09e-051891015bfb1c183a8a2752a2368b74150e66181c6a9da48
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK SPEG MATN2 MCAM FAT1

7.09e-0518910157ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPB MYLK WNT2 SVEP1 LRP1

7.09e-051891015324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCellfacs-Thymus-Epithelium-3m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK C16orf46 BMP1 FAT1 BHLHE22

7.09e-05189101514833feea8f80744a06ece73f813eaeff8c4dd61
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WNT2 PDE10A SVEP1 LRP1 GPSM2

7.09e-0518910152a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP MATN2 SVEP1 BMP1 KCNC4

7.27e-051901015f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

FLNC MYLK SPEG MCAM FAT1

7.27e-051901015645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CEBPB SPTLC2 VSIG4 IFNGR1 FCGBP

7.27e-0519010154498705c5c1c7ba88a26fd2f412cf1aadd0f572a
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

CEBPB MYLK WNT2 SVEP1 LRP1

7.45e-0519110153379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellP07-Mesenchymal-mesenchymal_fibroblast|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEBPB WNT2 SVEP1 LRP1 GPSM2

7.45e-051911015a05e9a7eb137d804570dd7d8905975d735738767
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CEBPB MYLK WNT2 SVEP1 LRP1

7.45e-051911015094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCellfacs-Lung-24m-Mesenchymal|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CEBPB MYLK WNT2 SVEP1 LRP1

7.45e-051911015ba02cbdfda6a94374a6472eb88499059979af472
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CEBPB MYLK WNT2 SVEP1 LRP1

7.45e-05191101580484d39f34703a33b9bac09826b7a526e883cab
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CEBPB MYLK WNT2 SVEP1 LRP1

7.45e-0519110155c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

ARRDC4 VSIG4 MYO1F LRP1 RAB7B

7.45e-051911015dab953682b8c9ed680a799161f837f792a7e4f33
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CEBPB VSIG4 IFNGR1 FCGBP MYO1F

7.45e-051911015b5715eeb72a97b7bc87b83f6c289e225f58da842
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARRDC4 VSIG4 MYO1F LRP1 RAB7B

7.64e-051921015bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK WNT2 SVEP1 LRP1 GPSM2

7.64e-0519210156f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWC2 CILP MATN2 SVEP1 LRP1

7.64e-051921015853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP MATN2 SVEP1 BMP1 LRP1

7.64e-051921015671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYLK WNT2 SVEP1 LRP1 GPSM2

7.64e-05192101525492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WNT2 PDE10A SVEP1 LRP1 GPSM2

7.64e-051921015f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWC2 FLNC MYLK SPEG FAT1

7.64e-0519210152cc712186e37fb21a964c032765c36a8b4a852cf
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWC2 CILP MATN2 SVEP1 LRP1

7.64e-051921015d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK WNT2 SVEP1 LRP1 GPSM2

7.64e-0519210153d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYLK WNT2 SVEP1 LRP1 GPSM2

7.64e-051921015de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP MATN2 SVEP1 BMP1 LRP1

7.64e-051921015840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWC2 CILP MATN2 SVEP1 LRP1

7.64e-05192101549281626ecad0456fdbded2378b7028d7b589686
ComputationalMetal / Ca ion binding.

TF LAP3 BMP1 FAT1 LRP1 LTF

1.22e-04133636MODULE_324
Drugvibrioferrin

TF LTF

1.91e-0521002CID000197680
Drugc111

TF LTF

1.91e-0521002CID000520630
Drugsodium ferrous citrate

TF LTF

1.91e-0521002CID000162114
DrugCp22

TF LTF

1.91e-0521002CID000121732
DrugCP-319743 [172078-87-4]; Up 200; 10uM; PC3; HT_HG-U133A

MYLK SETDB1 POLL ATP11A ALDH4A1 CTH EPHA5

2.03e-0518910077537_UP
Drugretinoic acid; Up 200; 1uM; MCF7; HG-U133A

WNT2 WNT7A RCC1 PFKL CDK10 KCNC4 MYO1F

2.17e-051911007224_UP
DrugAlbendazole [54965-21-8]; Down 200; 15uM; MCF7; HT_HG-U133A

LZTR1 MTF2 SPTLC2 RCC1 BMP1 PARP16 KBTBD11

2.25e-0519210073164_DN
DrugProcaine hydrochloride [51-05-8]; Up 200; 14.6uM; PC3; HT_HG-U133A

SPTLC2 SPEG MCAM RCC1 LRP1 ALDH4A1 GARRE1

2.65e-0519710071796_UP
DrugMyosmine [532-12-7]; Down 200; 27.4uM; PC3; HT_HG-U133A

SPTLC2 RCC1 CDK10 SVEP1 MFN1 POLL ALDH4A1

2.74e-0519810074293_DN
DrugPizotifen malate [5189-11-7]; Up 200; 9.4uM; HL60; HT_HG-U133A

CILP GRIN2A UNC45A F12 TAGLN3 POLL ALDH4A1

2.74e-0519810073134_UP
DrugTremorine dihydrochloride [300-68-5]; Down 200; 15uM; MCF7; HT_HG-U133A

LZTR1 MAN1C1 RCC1 DYSF POLL ALDH4A1 CTH

2.74e-0519810073196_DN
DrugMedrysone [2668-66-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A

FLNC CILP MAN1C1 WNT2 PDE10A BMP1 TAGLN3

2.83e-0519910073603_UP
DrugLabetalol hydrochloride [32780-64-6]; Up 200; 11uM; MCF7; HT_HG-U133A

FLNC MXRA5 CILP SPTLC2 VSIG4 GRIN2A TAGLN3

2.92e-0520010073167_UP
DrugEDDA

WNT2 TF LTF

3.60e-05151003CID000061974
DrugI ms

WNT2 DTYMK MFN1 BMP1 AIFM1

4.58e-05891005CID000013551
Diseasecystic fibrosis-related diabetes

CEBPB RAB7B

6.52e-054982EFO_0801077
DiseaseOvarian Mucinous Adenocarcinoma

MYLK NEK10 SPEG

1.49e-0431983C1335167
DiseaseMyofibrillar myopathy

FLNC MYOT

1.62e-046982cv:C2678065
Diseaseanemia (biomarker_via_orthology)

TF ALAS2

2.27e-047982DOID:2355 (biomarker_via_orthology)
DiseaseColorectal Carcinoma

FLNC MYOT LAMA1 OBSCN GRIN2A CUBN MFN1 FAT1 LRP1

5.55e-04702989C0009402
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIN2A F12

5.89e-0411982DOID:9279 (implicated_via_orthology)
Diseasecystic fibrosis associated meconium ileus

CEBPB RAB7B

9.68e-0414982EFO_0004608
Diseaseautism spectrum disorder (is_implicated_in)

ITGA4 MBD5

1.27e-0316982DOID:0060041 (is_implicated_in)
Diseasemuscular dystrophy (is_implicated_in)

MYOT DYSF

1.44e-0317982DOID:9884 (is_implicated_in)
DiseaseAlzheimer's disease (is_marker_for)

CEBPB GRIN2A MFN1 KCNC4 AIFM1

1.69e-03257985DOID:10652 (is_marker_for)
Diseasecystathionine measurement

PARD3B CTH

1.80e-0319982EFO_0010474
DiseaseAutistic Disorder

LZTR1 WNT2 GRIN2A ITGA4 TF

1.81e-03261985C0004352
Diseasedisease of metabolism (implicated_via_orthology)

PFKL ALDH4A1

2.20e-0321982DOID:0014667 (implicated_via_orthology)
Diseaselymphocyte:monocyte ratio

CEBPB ARID4B MTF2 ITGA4 LTF

2.78e-03288985EFO_0600088

Protein segments in the cluster

PeptideGeneStartEntry
TVGTDVSAKYRGAFC

ARID4B

11

Q4LE39
TVGTDVSAKYRGAFC

ARID4A

11

P29374
AKCVQSGDFVYFDGR

ATG14

56

Q6ZNE5
AGDAACFYDIKLGRR

AIFM1

436

O95831
FSVRAGYAGEDCPKA

ACTL6B

21

O94805
AGAALCLKYGESASR

BHLHE22

121

Q8NFJ8
CLKYGESASRGSVAE

BHLHE22

126

Q8NFJ8
ADTGGRKDVSYYIAC

EPHA5

381

P54756
ALVGTDAGEVTYFCK

CCDC77

151

Q9BR77
AALDGAKYCLAFASG

CTH

76

P32929
LAGGKCDDSVGYFVE

ALDH4A1

416

P30038
GFFAVYEAICGGDVK

BMP1

426

P13497
IANSAGYVGDRFKCV

BCOR

966

Q6W2J9
GLVFEDERKGCYSSG

ARRDC4

21

Q8NCT1
GSYRRGKATCGDVDV

POLL

416

Q9UGP5
DGCVAYAYGLKTADG

C16orf46

246

Q6P387
FGAAGRIACGEKYRV

MTF2

556

Q9Y483
ACGASVGYAVTKDGR

RCC1

351

P18754
TFYKGSDGCILAFDV

RAB7B

76

Q96AH8
GCYVAKEAGERTFRC

LRRC3C

51

A6NJW4
CFLSVEGTDGDKAYL

MFN1

111

Q8IWA4
YRSAGACTAAAFLKE

LAP3

456

P28838
KLVYAVSGGNEDSCF

FAT1

751

Q14517
GCNESFRAAIDKSYD

PARD3B

776

Q8TEW8
AALRSGDKAISYDGC

OR5B21

81

A6NL26
GDKAISYDGCAAQFF

OR5B21

86

A6NL26
VEGSAARFDCKIEGY

MYLK

1821

Q15746
KSGDCRAGVSFFEAA

GPSM2

36

P81274
YSGYALAEDGKRCVA

MATN2

306

O00339
KAYLEGAGAEFCDIT

LZTR1

656

Q8N653
KGLRASDAGAYTCVA

HMCN2

3286

Q8NDA2
ATDCSSYFRLGVKGV

LRP1

2641

Q07954
DDIRSFKEYSVRGCG

CFAP57

461

Q96MR6
LTADDAGKYRCGIAT

CD300H

101

A0A0K2S4Q6
EGFQASYGKDEDRAC

NEK10

866

Q6ZWH5
REDAGVYVCKATNGF

FGFRL1

91

Q8N441
ATKADGFALYFLGEC

PDE10A

106

Q9Y233
NLYSSEGKGVFDCRT

PFKL

641

P17858
FEDRKDGSCGVSYVV

FLNC

2361

Q14315
RGYAFITFCGKEAAQ

HNRNPR

206

O43390
KAFGCVGGYIASTRD

ALAS2

391

P22557
SYARGDCKDFEALLA

PARP16

46

Q8N5Y8
KTDAGDYSCEARGQR

OBSCN

1046

Q5VST9
AGEYSCKAGDQRLSF

OBSCN

1601

Q5VST9
KASFRAVYQVACGDE

CUBN

806

O60494
CVKTADFGLARAYGV

CDK10

176

Q15131
AKAIGYATAADCGRT

FCGBP

421

Q9Y6R7
YEADCLAAAYGGKAA

CEBPB

31

P17676
KEAGCYNGITSRDDF

GARRE1

376

O15063
ALEKYCRTEAGFSGI

MAN1C1

551

Q9NR34
VNEGDGFEYFKSASC

MBD5

1176

Q9P267
KLGSYFGASVCAVDL

ITGA4

301

P13612
LGSKVGYQVRFDDCS

DHX40

126

Q8IX18
FFASIGEREKCGSYL

DYSF

1481

O75923
SAYAKSEEFAVCRDG

IFNGR1

111

P15260
KLTFQCGSDAGYDRF

LILRA3

241

Q8N6C8
TSACVAVYKDGRAGV

HSPA14

11

Q0VDF9
CDFGISGYLVDSVAK

MAP2K6

196

P52564
DLKREAGGGYRCVAS

MCAM

396

P43121
LGAELGCAKAFYAAS

FOXD2

356

O60548
GAFCDVDTKASCYDG

F12

206

P00748
GFDSEFCKALRAYAG

RGMB

76

Q6NW40
YSGAFKCLRDGAGDV

LTF

211

P02788
ACDAVFVAGKESRGA

TMEM132A

456

Q24JP5
ALGSVAVTKDDGCYR

TAGLN3

131

Q9UI15
ADGFYGDAVTAKNCR

LAMA1

886

P25391
FLSKGADVNECDFYG

RNASEL

111

Q05823
AAYFGQKDSVCGVSE

POLR3A

1331

O14802
KGRFVCEYAGEVLGF

SETMAR

161

Q53H47
AFYAAVAADCFRDGV

SLC12A1

746

Q13621
DGVAGYRCTCVKGFV

SVEP1

1286

Q4LDE5
SGDADARGDAAVYCF

KBTBD11

316

O94819
DDIAKGSFVCIYAGK

SETDB1

821

Q15047
AGEYFCKAQSDAGAV

CILP

371

O75339
GECAYLNDKGASSAR

CLEC2D

161

Q9UHP7
SATGEIYLFCKGADS

ATP11A

566

P98196
PSCTVGFYAGDRKEF

ATG4D

391

Q86TL0
GFYAGDRKEFETLCS

ATG4D

396

Q86TL0
KGDETAAREFCGSFQ

TIGD2

146

Q4W5G0
RGKGCVDESGFVYAI

VWC2

151

Q2TAL6
GCSDNIDYGIKFARA

WNT2

156

P09544
YTGAFRCLVEKGDVA

TF

536

P02787
AAERGDAGFYTCKAV

SPEG

931

Q15772
AAAKVLEEYGAGVCS

SPTLC2

191

O15270
CFGGRDYVFAKAIGD

GTF2A1L

461

Q9UNN4
CLAFGTDDGKVGLYD

GEMIN5

441

Q8TEQ6
EGRRAVKAGAYAACQ

UBR1

266

Q8IWV7
AVIADSGSYFCTAKG

VSIG4

201

Q9Y279
YDTVAGADKFGNICV

SF3B3

1041

Q15393
DDYRGKGCVDDSGFV

VWC2L

46

B2RUY7
GCSADIRYGIGFAKV

WNT7A

151

O00755
TCREGGKDFVATAGF

ZNF792

211

Q3KQV3
DVCGKAFSYSSGLAV

ZFP62

396

Q8NB50
GYASEEKVIFRYCAG

PSPN

81

O60542
TTGAAASAAEYGFRK

UHMK1

61

Q8TAS1
TRAAAACLDKAVEYG

UNC45A

921

Q9H3U1
VKAGDSGRYTCRAEN

SIGLEC16

296

A6NMB1
YEERACEGGKFATVE

HEBP1

31

Q9NRV9
DYACADGSVRKGTFV

KCNC4

596

Q03721
DRYAFSGVAFTGAKE

DTYMK

96

P23919
AGKVSYDVSGFCERN

MYO1F

506

O00160
FYGGDLKVDCVATGL

MXRA5

2256

Q9NR99
GKEYEFCVRSVSEAG

MYOM3

666

Q5VTT5
SDAGAYACVAKNRAG

MYOT

316

Q9UBF9
DAAVLNYKAGRDEGC

GRIN2A

731

Q12879