Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Ig_E-set	FLNC RBPJ	6.60e-03	104	22	2	IPR014756
Domain	7TM_GPCR_Srsx	CHRM4 GPR19	7.61e-03	112	22	2	SM01381
Pubmed	M. tuberculosis-Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1.	GRB2 IGF2R	1.15e-06	3	22	2	28978467
Pubmed	SH3 binding domains in the dopamine D4 receptor.	GRB2 CHRM4	8.01e-06	7	22	2	9843378
Pubmed	Identification of genes showing altered expression in preimplantation and early postimplantation parthenogenetic embryos.	COX7C IGF2R	1.37e-05	9	22	2	8565329
Pubmed	Role of Tet1 in erasure of genomic imprinting.	SGCE IGF2R	2.51e-05	12	22	2	24291790
Pubmed	Generalized disruption of inherited genomic imprints leads to wide-ranging placental defects and dysregulated fetal growth.	SGCE IGF2R	5.81e-05	18	22	2	23085235
Pubmed	The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis.	GRB2 GPR19	5.81e-05	18	22	2	34407391
Pubmed	Disruption of parental-specific expression of imprinted genes in uniparental fetuses.	SGCE IGF2R	1.53e-04	29	22	2	16987518
Pubmed	TAPP2 links phosphoinositide 3-kinase signaling to B-cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B-cell leukemia.	GRB2 SEC23A	3.09e-04	41	22	2	19786618
Pubmed	Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions.	GRB2 FLNC	5.16e-04	53	22	2	15306695
GeneFamily	G protein-coupled receptors, Class A orphans	GPR87 GPR19	8.09e-04	78	10	2	262
ToppCell	facs-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COX7C SIDT2 SEC23A IGF2R	2.40e-06	196	22	4	44f5b1b474399c9316729155f2ea95a82ca66e30
ToppCell	facs-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COX7C SIDT2 SEC23A IGF2R	2.40e-06	196	22	4	c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
Disease	lysophosphatidylethanolamine 20:4 measurement	SEC23A GCKR	2.13e-04	29	22	2	EFO_0010370
Disease	cholesteryl esters to total lipids in medium LDL percentage	GCKR IGF2R	3.48e-04	37	22	2	EFO_0022252
Disease	triglycerides in large LDL measurement	GCKR IGF2R	4.70e-04	43	22	2	EFO_0022319
Disease	triacylglycerol 56:6 measurement	GCKR FCGBP	4.70e-04	43	22	2	EFO_0010433
Disease	phospholipids in medium LDL measurement	GCKR IGF2R	6.11e-04	49	22	2	EFO_0022183
Disease	total lipids in LDL measurement	GCKR IGF2R	6.88e-04	52	22	2	EFO_0022308
Disease	total lipids in medium VLDL	GCKR IGF2R	7.42e-04	54	22	2	EFO_0022153
Disease	triglycerides in LDL measurement	GCKR IGF2R	7.98e-04	56	22	2	EFO_0022320
Disease	total lipids in large LDL	GCKR IGF2R	8.26e-04	57	22	2	EFO_0022163
Disease	cholesterol in large LDL measurement	GCKR IGF2R	8.26e-04	57	22	2	EFO_0021901
Disease	triglycerides in IDL measurement	GCKR IGF2R	8.55e-04	58	22	2	EFO_0022149
Disease	phospholipids in small LDL measurement	GCKR IGF2R	8.85e-04	59	22	2	EFO_0022297
Disease	phospholipids in VLDL measurement	GCKR IGF2R	8.85e-04	59	22	2	EFO_0022301
Disease	cholesteryl ester measurement	SIDT2 GCKR IGF2R	8.90e-04	257	22	3	EFO_0010351
Disease	total lipids in VLDL measurement	GCKR IGF2R	9.15e-04	60	22	2	EFO_0022314
Disease	free cholesterol in VLDL measurement	GCKR IGF2R	9.46e-04	61	22	2	EFO_0022276
Disease	triglycerides in medium LDL measurement	GCKR IGF2R	9.77e-04	62	22	2	EFO_0022322
Disease	triglyceride measurement, high density lipoprotein cholesterol measurement	GRB2 GCKR IGF2R	1.07e-03	274	22	3	EFO_0004530, EFO_0004612
Disease	cholesterol in very large VLDL measurement	GCKR IGF2R	1.07e-03	65	22	2	EFO_0022230
Disease	cholesterol in large VLDL measurement	GCKR IGF2R	1.07e-03	65	22	2	EFO_0021902
Disease	total lipids in small VLDL	GCKR IGF2R	1.14e-03	67	22	2	EFO_0022148
Disease	triglycerides in very small VLDL measurement	GCKR IGF2R	1.17e-03	68	22	2	EFO_0022144
Disease	monounsaturated fatty acids; 16:1, 18:1 measurement	GCKR IGF2R	1.54e-03	78	22	2	EFO_0022187

Protein segments in the cluster

Peptide	Gene	Start	Entry
VRLVTSSSHNRYETV	CHRM4	16	P08173
IRRFTTSVVRRSHYE	COX7C	6	P15954
HRSRRTQSTTNYFVV	GPR19	91	Q15760
QQFKQYSRHVTTRAA	M1AP	121	Q8TC57
QERLTRTFTRSSHTY	FLNC	2171	Q14315
RTFTRSSHTYTRTER	FLNC	2176	Q14315
LVDYHRSTSVSRNQQ	GRB2	131	P62993
RYIHKSSRQFISQSS	GPR87	231	Q9BY21
LRTFERAHQVTYSQS	GCKR	296	Q14397
HRGSQTVSYTRAVRV	FCGBP	911	Q9Y6R7
HRGSQAVSYTRSVTL	FCGBP	3321	Q9Y6R7
RTHFVISTYREQLQR	C5orf34	56	Q96MH7
SEVRYNQRSQTSRTR	nan	371	A6NNC1
EVRYNQRSQTSRTRS	nan	646	A6NNC1
RQTTYTTRIHLVCSR	IGF2R	881	P11717
YTFNHTVTRNRTEGV	SIDT2	51	Q8NBJ9
TTYRVVAHSSVFRVL	ST6GALNAC6	151	Q969X2
ITAYNRRTFETARHN	SGCE	131	O43556
FVTQYQHSSGQRRIR	SEC23A	481	Q15436
RIYFVDHNNRTTQFT	SMURF1	321	Q9HCE7
FENVTFTYRTRPHTQ	ABCB9	506	Q9NP78
TSAHQSSFRIQIYRI	VPS13A	2636	Q96RL7
NRLRSQTVSTRYLHV	RBPJ	191	Q06330
ARVIVLSSSHSYQRN	PSMG2	116	Q969U7
KTFTTRSYRNRHQQF	ZNF584	361	Q8IVC4
RSFSQKSTLVYHQRT	ZNF337	411	Q9Y3M9