Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
MousePheno	decreased vocalization	ARHGAP32 LBR SHANK2 HNRNPU	9.51e-06	46	41	4	MP:0020351
Domain	PTPc	PTPRH PTPN20	3.54e-03	36	46	2	SM00194
Domain	TYR_PHOSPHATASE_PTP	PTPRH PTPN20	4.15e-03	39	46	2	PS50055
Domain	PTPase_domain	PTPRH PTPN20	4.58e-03	41	46	2	IPR000242
Domain	Y_phosphatase	PTPRH PTPN20	4.58e-03	41	46	2	PF00102
Domain	PX	ARHGAP32 PIK3C2A	6.48e-03	49	46	2	PF00787
Domain	PX	ARHGAP32 PIK3C2A	6.74e-03	50	46	2	PS50195
Domain	-	ARHGAP32 PIK3C2A	7.01e-03	51	46	2	3.30.1520.10
Domain	Phox	ARHGAP32 PIK3C2A	7.28e-03	52	46	2	IPR001683
Pubmed	Mesocortical Dopamine Phenotypes in Mice Lacking the Sonic Hedgehog Receptor Cdon.	MKI67 NR4A2	1.12e-05	4	48	2	27419218
Pubmed	Wnt2 regulates progenitor proliferation in the developing ventral midbrain.	MKI67 NR4A2	1.12e-05	4	48	2	20018874
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	SEMA3A NAV2 PNRC2 CEP152 SHANK2 PZP TEX35 SUSD1	1.43e-05	814	48	8	23251661
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDK9 NAV2 ARHGAP32 CEP152 LBR PIK3C2A KIAA1217 MBD1	2.14e-05	861	48	8	36931259
Pubmed	The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.	LBR HNRNPU	2.79e-05	6	48	2	25915022
Pubmed	Nav2 hypomorphic mutant mice are ataxic and exhibit abnormalities in cerebellar development.	MKI67 NAV2	2.79e-05	6	48	2	21419114
Pubmed	Expression pattern of Nav2 in the murine CNS with development.	MKI67 NAV2	3.90e-05	7	48	2	32081718
Pubmed	The protein interaction landscape of the human CMGC kinase group.	CDK9 CHD2 MAGOH ZNF510 LBR SHANK2 HNRNPR	4.46e-05	695	48	7	23602568
Pubmed	Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein.	HNRNPU HNRNPR	5.19e-05	8	48	2	19808671
Pubmed	Functional specialization of beta-arrestin interactions revealed by proteomic analysis.	ARHGAP32 LBR PIK3C2A HNRNPU HNRNPR	7.57e-05	317	48	5	17620599
Pubmed	Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.	ARHGAP32 PIK3C2A BIRC6	7.99e-05	60	48	3	34761192
Pubmed	Dosage-dependent requirements of Magoh for cortical interneuron generation and survival.	MKI67 MAGOH	8.33e-05	10	48	2	31857347
Pubmed	Prolonged Mitosis of Neural Progenitors Alters Cell Fate in the Developing Brain.	MKI67 MAGOH	8.33e-05	10	48	2	26748089
Pubmed	HIV-1 Vif promotes the G₁- to S-phase cell-cycle transition.	CDK9 HNRNPU	8.33e-05	10	48	2	21149631
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MKI67 CHD2 LBR PIK3C2A BIRC6 SLC27A4 HNRNPU HNRNPR SMTN	8.47e-05	1353	48	9	29467282
Pubmed	Tcf12 Is Involved in Early Cell-Fate Determination and Subset Specification of Midbrain Dopamine Neurons.	MKI67 NR4A2	1.02e-04	11	48	2	29163030
Pubmed	Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis.	MKI67 NR4A2	1.02e-04	11	48	2	21347250
Pubmed	Regulation of Tlx3 by Pax6 is required for the restricted expression of Chrnα3 in Cerebellar Granule Neuron progenitors during development.	MKI67 ASTN1	1.02e-04	11	48	2	27452274
Pubmed	Pias1 is essential for erythroid and vascular development in the mouse embryo.	MKI67 SEMA3A	1.02e-04	11	48	2	27155222
Pubmed	RNF125 attenuates hepatocellular carcinoma progression by downregulating SRSF1-ERK pathway.	HNRNPU HNRNPR	1.02e-04	11	48	2	37142680
Pubmed	Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development.	MKI67 NR4A2	1.22e-04	12	48	2	23444360
Pubmed	New functions of Semaphorin 3E and its receptor PlexinD1 during developing and adult hippocampal formation.	SEMA3A SYNPR	1.22e-04	12	48	2	29358640
Pubmed	SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells.	MKI67 NR4A2	1.22e-04	12	48	2	22290867
Pubmed	Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors.	MKI67 NR4A2	1.22e-04	12	48	2	27246266
Pubmed	Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome.	MKI67 SEMA3A	1.22e-04	12	48	2	27693255
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	MKI67 CEP152 PIK3C2A SMTN	1.23e-04	184	48	4	32908313
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	NAV2 C4orf17 CHD2 SHANK2 TEX35 SUSD1 SLC27A4 HNRNPU HNRNPR	1.37e-04	1442	48	9	35575683
Pubmed	Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling.	MKI67 SLC27A4	1.44e-04	13	48	2	20513444
Pubmed	Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins.	HNRNPU HNRNPR	1.44e-04	13	48	2	17765891
Pubmed	hnRNPU is required for spermatogonial stem cell pool establishment in mice.	MKI67 HNRNPU	1.44e-04	13	48	2	38625792
Pubmed	Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon.	MKI67 NR4A2	1.44e-04	13	48	2	16438966
Pubmed	Laminin α2 controls mouse and human stem cell behaviour during midbrain dopaminergic neuron development.	MKI67 NR4A2	1.68e-04	14	48	2	31371375
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	LRP2 MAGOH LBR SMCR8 PIK3C2A BIRC6 NDUFAF7 KIAA1217 HNRNPR	1.81e-04	1496	48	9	32877691
Pubmed	Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.	MAGOH HNRNPU HNRNPR	1.88e-04	80	48	3	11991638
Pubmed	Developmental Requirement of Homeoprotein Otx2 for Specific Habenulo-Interpeduncular Subcircuits.	MKI67 NR4A2	1.94e-04	15	48	2	30593496
Pubmed	Quantitative trait loci for steady-state platelet count in mice.	ASTN1 LBR	1.94e-04	15	48	2	15520881
Pubmed	Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis.	HNRNPU HNRNPR	1.94e-04	15	48	2	28784777
Pubmed	Ebf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse.	MKI67 NR4A2	1.94e-04	15	48	2	25762221
Pubmed	Identification of glucocorticoid-regulated genes that control cell proliferation during murine respiratory development.	MKI67 CHIA	1.94e-04	15	48	2	17901120
Pubmed	Pivotal roles of Fezf2 in differentiation of cone OFF bipolar cells and functional maturation of cone ON bipolar cells in retina.	MKI67 TRPM1	2.21e-04	16	48	2	29559301
Pubmed	Zinc finger genes Fezf1 and Fezf2 control neuronal differentiation by repressing Hes5 expression in the forebrain.	MKI67 NR4A2	2.21e-04	16	48	2	20431123
Pubmed	Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons.	MKI67 NR4A2	2.21e-04	16	48	2	16410412
Pubmed	Proteomic analysis of NMDA receptor-adhesion protein signaling complexes.	APPL1 SHANK2 HNRNPU	2.33e-04	86	48	3	10862698
Pubmed	A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons.	HNRNPU HNRNPR	2.50e-04	17	48	2	12388589
Pubmed	Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons.	MKI67 NR4A2	2.50e-04	17	48	2	20610763
Pubmed	Lmx1b is essential for Fgf8 and Wnt1 expression in the isthmic organizer during tectum and cerebellum development in mice.	MKI67 NR4A2	2.81e-04	18	48	2	17166916
Pubmed	Snf2l regulates Foxg1-dependent progenitor cell expansion in the developing brain.	MKI67 NR4A2	2.81e-04	18	48	2	22516202
Pubmed	Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon.	MKI67 NR4A2	2.81e-04	18	48	2	18820178
Pubmed	Loss of Dmrt5 Affects the Formation of the Subplate and Early Corticogenesis.	MKI67 NR4A2	3.14e-04	19	48	2	31845734
Pubmed	Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription.	MKI67 SYNPR	3.14e-04	19	48	2	31442405
Pubmed	PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier.	MKI67 SLC27A4	3.14e-04	19	48	2	28369476
Pubmed	Disruption of the lamin A and matrin-3 interaction by myopathic LMNA mutations.	LBR HNRNPU HNRNPR	3.22e-04	96	48	3	25948554
Pubmed	Germline Chd8 haploinsufficiency alters brain development in mouse.	MKI67 HNRNPR	3.49e-04	20	48	2	28671691
Pubmed	A key role for the HLH transcription factor EBF2COE2,O/E-3 in Purkinje neuron migration and cerebellar cortical topography.	MKI67 SEMA3A	3.49e-04	20	48	2	16774995
Pubmed	Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia.	MKI67 CHIA	3.85e-04	21	48	2	15514019
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	TTC21B ARHGAP32 CEP152 BIRC6	4.02e-04	251	48	4	29778605
Pubmed	The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart.	MKI67 SEMA3A	4.23e-04	22	48	2	36877136
Pubmed	Ctip1 Regulates the Balance between Specification of Distinct Projection Neuron Subtypes in Deep Cortical Layers.	MKI67 NR4A2	4.23e-04	22	48	2	27117402
Pubmed	Serum response factor is required for cortical axon growth but is dispensable for neurogenesis and neocortical lamination.	MKI67 NR4A2	4.63e-04	23	48	2	22090492
Pubmed	Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo.	MKI67 NR4A2	4.63e-04	23	48	2	18953410
Pubmed	Comprehensive proteomic analysis of the human spliceosome.	MAGOH HNRNPU HNRNPR	4.67e-04	109	48	3	12226669
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	MKI67 ARHGAP32 LBR KIAA1217	4.79e-04	263	48	4	34702444
Pubmed	Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype.	MKI67 NR4A2	5.05e-04	24	48	2	34061953
Pubmed	Fibroblast growth factor 2 regulates dopaminergic neuron development in vivo.	MKI67 NR4A2	5.05e-04	24	48	2	22537018
Pubmed	Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium.	MKI67 SMTN	5.05e-04	24	48	2	21803035
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	LRP2 TMEM260 CHD2 BIRC6 HNRNPU HNRNPR	5.07e-04	736	48	6	29676528
Pubmed	Motor innervation directs the correct development of the mouse sympathetic nervous system.	MKI67 SEMA3A	5.48e-04	25	48	2	39152112
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TTC21B APPL1 ARHGAP32 CEP152 BIRC6	5.81e-04	493	48	5	15368895
Pubmed	DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC.	MKI67 MAGOH HNRNPR	5.89e-04	118	48	3	37105989
Pubmed	LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli.	MKI67 LRP2	5.93e-04	26	48	2	26439398
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	APPL1 CHD2 PIK3C2A BIRC6 HNRNPR	6.03e-04	497	48	5	23414517
Pubmed	KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.	CDK9 LBR HNRNPU HNRNPR	6.14e-04	281	48	4	26725010
Pubmed	A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.	MKI67 LBR HNRNPR	6.34e-04	121	48	3	22412018
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	MKI67 CHD2 PZP HNRNPU	6.38e-04	284	48	4	29459677
Pubmed	Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory.	MKI67 CHD2	6.40e-04	27	48	2	30344048
Pubmed	Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.	MKI67 LRP2	6.40e-04	27	48	2	28167773
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	CDK9 CHD2 MAGOH LBR PZP HNRNPU HNRNPR	6.69e-04	1082	48	7	38697112
Pubmed	Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.	MKI67 HNRNPU HNRNPR	6.80e-04	124	48	3	23000965
Pubmed	COUP-TFII controls amygdala patterning by regulating neuropilin expression.	MKI67 SEMA3A	6.89e-04	28	48	2	22492355
Pubmed	The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone.	MKI67 NR4A2	6.89e-04	28	48	2	18794345
Pubmed	Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development.	MKI67 SEMA3A	6.89e-04	28	48	2	37846569
Pubmed	Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases.	CDK9 LBR HNRNPU HNRNPR	7.36e-04	295	48	4	26209609
Pubmed	YAP and TAZ are required for the postnatal development and the maintenance of the structural integrity of the oviduct.	MKI67 SMTN	7.39e-04	29	48	2	32520726
Pubmed	Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors.	MKI67 NR4A2	7.92e-04	30	48	2	21880902
Pubmed	Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development.	MKI67 NR4A2	8.45e-04	31	48	2	23895693
Pubmed	Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells.	MKI67 NR4A2	8.45e-04	31	48	2	19796621
Pubmed	A COFRADIC protocol to study protein ubiquitination.	MKI67 HNRNPU HNRNPR	8.52e-04	134	48	3	24816145
Pubmed	Proteomic analysis of complexes formed by human topoisomerase I.	MKI67 HNRNPR	9.01e-04	32	48	2	15848144
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	ASTN1 APPL1 ARHGAP32 SHANK2 BIRC6 KIAA1217 HNRNPU	9.04e-04	1139	48	7	36417873
Pubmed	Large-scale analysis of the human ubiquitin-related proteome.	MKI67 BIRC6 HNRNPU HNRNPR	9.17e-04	313	48	4	16196087
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	MKI67 LRP2 CHIA BIRC6	9.17e-04	313	48	4	20800603
Pubmed	Distinct expression of select and transcriptome-wide isolated 3'UTRs suggests critical roles in development and transition states.	MKI67 NR4A2	9.58e-04	33	48	2	33951080
Pubmed	Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency.	MKI67 LRP2	1.02e-03	34	48	2	35341793
Pubmed	Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells.	MKI67 NR4A2	1.02e-03	34	48	2	31569049
Pubmed	Defining the membrane proteome of NK cells.	MKI67 CDK9 LBR PIK3C2A BIRC6 SLC27A4 HNRNPU	1.05e-03	1168	48	7	19946888
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	NAV2 ARHGAP32 LBR SHANK2 KIAA1217	1.07e-03	565	48	5	25468996
Pubmed	WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis.	MKI67 LRP2	1.08e-03	35	48	2	30940800
Pubmed	Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development.	MKI67 NR4A2	1.08e-03	35	48	2	22991445
Pubmed	Inflammation-like changes in the urothelium of Lifr-deficient mice and LIFR-haploinsufficient humans with urinary tract anomalies.	MKI67 LRP2	1.08e-03	35	48	2	32179912
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	MKI67 LRP2 SHANK2 HNRNPR	1.10e-03	329	48	4	17474147
Interaction	CDH1 interactions	MKI67 NAV2 ARHGAP32 MAGOH ZNF510 LBR SHANK2 KIAA1217 SLC27A4 PTPRQ	8.77e-06	768	47	10	int:CDH1
Cytoband	1q25.2	ASTN1 TEX35	4.88e-04	31	48	2	1q25.2
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRH PTPRQ	6.24e-04	21	32	2	813
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NAV2 CHD2 SHANK2 KIAA1217 FAAH2	1.29e-06	176	48	5	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	SEMA3A LRP2 TRPM1 SYNPR KIAA1217	2.14e-06	195	48	5	2fa0216ba493d9722324c0a9a0c59c40e72b3c4e
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells-retina_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	SEMA3A LRP2 TRPM1 SYNPR KIAA1217	2.14e-06	195	48	5	06a437459717dc3c41ec343b1ec57cf910ecbdd8
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3A LRP2 ASTN1 PTPRQ	2.65e-05	160	48	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3A LRP2 ASTN1 PTPRQ	2.65e-05	160	48	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAV2 SHANK2 SUSD1 PTPRQ	2.72e-05	161	48	4	0d863d7d369391dd6148e1de6d6f8033dcb8fe0f
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRP2 ASTN1 TRPM1 PTPRQ	3.29e-05	169	48	4	6937c46b119d4ce382fc8c2fa5925ede5ae89c81
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRP2 ASTN1 TRPM1 PTPRQ	3.29e-05	169	48	4	0cece9b2bb1f58e465c20ec8735a4fc3c1021f03
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APPL1 PTPRH PIK3C2A SLC27A4	3.60e-05	173	48	4	e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCell	facs-Large_Intestine-Proximal-3m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APPL1 PTPRH PIK3C2A SLC27A4	3.60e-05	173	48	4	99532bb768ee35fed939a377acb5215d3f8904bd
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NAV2 SHANK2 KIAA1217 FAAH2	4.20e-05	180	48	4	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 LRP2 CHIA NRROS	4.39e-05	182	48	4	81c394959414173016426961478f670cd822f8b3
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 LRP2 CHIA NRROS	4.39e-05	182	48	4	41a7543c8b703441ff6ac2307faffe5f798b2c41
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	NAV2 SHANK2 KIAA1217 FAAH2	4.67e-05	185	48	4	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	NAV2 SHANK2 KIAA1217 FAAH2	4.98e-05	188	48	4	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NAV2 SHANK2 KIAA1217 PTPRQ	5.29e-05	191	48	4	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LRP2 NAV2 SYNPR PTPRQ	5.29e-05	191	48	4	4c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	APPL1 SMCR8 PIK3C2A BIRC6	5.51e-05	193	48	4	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Gad2-Th.Crhbp_(Supramammillary_Nucleus_(SuM)_Dopaminergic?,_Th+/Ddc+)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SEMA3A PZP PTPRQ	5.68e-05	69	48	3	f9c1b871e594e57f0d6da3754f76ee41189f4633
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Gad2-Th.Crhbp_(Supramammillary_Nucleus_(SuM)_Dopaminergic?,_Th+/Ddc+)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SEMA3A PZP PTPRQ	5.68e-05	69	48	3	ee2c7b86ef336c7d0c82a8950bf64457f2683732
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Gad2-Th.Crhbp_(Supramammillary_Nucleus_(SuM)_Dopaminergic?,_Th+/Ddc+)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SEMA3A PZP PTPRQ	5.68e-05	69	48	3	57df6acddf5fe7a1d6bc551c3e3de44102f2f1db
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MKI67 NAV2 LBR RHNO1	5.73e-05	195	48	4	742c82c86487314cdb3178012004adb1164bcbdb
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 SHANK2 KIAA1217 FAAH2	5.73e-05	195	48	4	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	MKI67 NAV2 SHANK2 KIAA1217	5.85e-05	196	48	4	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	MKI67 NAV2 SHANK2 KIAA1217	5.85e-05	196	48	4	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NR4A2 NAV2 SHANK2 PTPRQ	5.97e-05	197	48	4	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PNRC2 CHD2 LBR HNRNPU	6.08e-05	198	48	4	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MKI67 NAV2 LBR RHNO1	6.08e-05	198	48	4	c3dd887c95587f930b7afd32385627a9fa029ca4
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_dorsal_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	MKI67 LBR RHNO1 SMTN	6.08e-05	198	48	4	5f0964c3aa7e1dc52cbb46e754078920b65bcb88
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	MKI67 LBR RHNO1 SMTN	6.08e-05	198	48	4	629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NAV2 SHANK2 KIAA1217 FAAH2	6.08e-05	198	48	4	5fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MKI67 NAV2 CEP152 LBR	6.20e-05	199	48	4	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	Biopsy_IPF-Mesenchymal-Mesothelial_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	LRP2 ASTN1 SLITRK2 PTPRQ	6.33e-05	200	48	4	553386523fd8f8f36617a0d81032224b7ddce442
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	MKI67 NAV2 CEP152 LBR	6.33e-05	200	48	4	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 SHANK2 KIAA1217 FAAH2	6.33e-05	200	48	4	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors_nGenesUnder4k\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	MKI67 MAGOH LBR RHNO1	6.33e-05	200	48	4	243c7f88befd402a57e9226706811c802b28e3fd
Computational	Neighborhood of TDG	MAGOH HNRNPU HNRNPR	7.81e-05	35	26	3	GNF2_TDG
Computational	Neighborhood of HDAC1	PNRC2 MAGOH HNRNPU HNRNPR	1.30e-04	110	26	4	GNF2_HDAC1
Computational	Neighborhood of DAP3	PNRC2 MAGOH HNRNPU HNRNPR	1.77e-04	119	26	4	GNF2_DAP3
Computational	Neighborhood of KPNB1	MAGOH HNRNPU HNRNPR	6.98e-04	73	26	3	GNF2_KPNB1
Disease	Intellectual Disability	NR4A2 LRP2 ASTN1 SHANK2 HNRNPU HNRNPR	5.77e-05	447	45	6	C3714756
Disease	macula measurement	LRP2 NAV2 ARHGAP32 TRPM1	1.98e-04	189	45	4	EFO_0008375
Disease	Epilepsy	ASTN1 CHD2 HNRNPU	6.21e-04	109	45	3	C0014544
Disease	Epileptic encephalopathy	CHD2 HNRNPU	9.63e-04	30	45	2	C0543888
Disease	autism spectrum disorder (implicated_via_orthology)	ARHGAP32 CHD2 SHANK2	1.62e-03	152	45	3	DOID:0060041 (implicated_via_orthology)
Disease	corpus callosum anterior volume measurement	SEMA3A NAV2	1.63e-03	39	45	2	EFO_0010295

Protein segments in the cluster

Peptide	Gene	Start	Entry
IFFQNKYRENNRGPL	SYNPR	101	Q8TBG9
SNRTNPAVGYKLAFN	TTC21B	1261	Q7Z4L5
RPYTNGQKQEFNNQA	CEP152	151	O94986
PLNSANNAQYFLRKP	BIRC6	1946	Q9NR09
AVRANGLYPVANNRN	CHIA	431	Q9BZP6
RINNKARAGSAFLNP	ASTN1	331	O14525
LAYAFSLLGKQNQNR	PZP	1156	P20742
FRGANSQKNAFRKNP	LBR	501	Q14739
QANGAYSREQFKPQA	C22orf23	101	Q9BZE7
TKALRAFQGYSNNQP	MCMDC2	211	Q4G0Z9
FRPDGKLRYANNSNY	MAGOH	26	P61326
FPVNRNLTRKAGYLN	APPL1	271	Q9UKG1
LQPYTNRRQNRKCGA	MBD1	326	Q9UIS9
PRLLFKSQANQNYAG	PNRC2	81	Q9NPJ4
TYSKQAAFQNGFNPR	PIK3C2A	161	O00443
FRGRGNNRGYKNQSQ	HNRNPU	786	Q00839
DGYNQPDSKRRQTNN	HNRNPR	576	O43390
KRAYIPNFESGRNNL	LRP2	4116	P98164
ARPYRVLNNFISNQK	MKI67	731	P46013
LQPAQRYNQARGKFV	OR2I1P	261	Q8NGU4
NRDFAFYNPRLQGKS	ARHGAP32	1686	A7KAX9
RAKNRFPNIKPYNNN	PTPRQ	2061	Q9UMZ3
NSGNQPSNREKNRYR	PTPN20	176	Q4JDL3
QRERKFNYGGGNNNP	CHD2	1641	O14647
GQSNYLEKNRIPFAN	C4orf17	66	Q53FE4
SNKIYGRSNNPYDLQ	FAAH2	186	Q6GMR7
ARAFSLAKNSQPNRY	CDK9	171	P50750
SQNQFQYLPDGFLRK	NRROS	336	Q86YC3
FNNGGLNRPNYLSKL	NR4A2	541	P43354
GSLFPAYQKHQNRAR	RHNO1	66	Q9BSD3
LGAAASYFKLNNRRN	XG	156	P55808
GRYQRNARQSKPFAS	NDUFAF7	416	Q7L592
NRRSQSFNNYDKSKP	NAV2	306	Q8IVL1
KRQFAPSYESRRQNQ	SLITRK2	781	Q9H156
QDPRQYRQANGSAKK	KIAA1217	1771	Q5T5P2
LTARANYQNGKNNVP	SEMA3A	16	Q14563
AGQNALKFIRQYPFA	SMCR8	706	Q8TEV9
LYSRNAGPQANFRNK	SHANK2	966	Q9UPX8
GFRKQPYDNPVRTNQ	TM9SF4	471	Q92544
PLRRFDGYLNQGANN	SLC27A4	456	Q6P1M0
GSFPKQLRPNYQLNS	SPATA31D1	436	Q6ZQQ2
YRATNNNKTFIPNDG	SUSD1	106	Q6UWL2
NRKLIYNFKQGNFPR	SIRPD	71	Q9H106
RKNFRTLYNNLFGPK	TRPM1	551	Q7Z4N2
YELNPSGNNFNRKAH	ZNF510	336	Q9Y2H8
LCALKNNYNRGNIPS	TEX35	186	Q5T0J7
ASENNAKNRYRNVLP	PTPRH	841	Q9HD43
FDYGQLSPQNRRQNF	SMTN	846	P53814
FRLYSQKAPNDPQQA	TMEM260	671	Q9NX78