Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	bitter taste receptor activity	TAS2R40 TAS2R39 TAS2R60	2.90e-04	27	96	3	GO:0033038
GeneOntologyMolecularFunction	RNA polymerase III type 3 promoter sequence-specific DNA binding	MTOR SNAPC4	3.39e-04	6	96	2	GO:0001006
GeneOntologyMolecularFunction	RNA polymerase III cis-regulatory region sequence-specific DNA binding	MTOR SNAPC4	4.73e-04	7	96	2	GO:0000992
GeneOntologyMolecularFunction	taste receptor activity	TAS2R40 TAS2R39 TAS2R60	5.29e-04	33	96	3	GO:0008527
GeneOntologyMolecularFunction	RNA polymerase III transcription regulatory region sequence-specific DNA binding	MTOR SNAPC4	6.29e-04	8	96	2	GO:0001016
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	DCAF1 PRAMEF7 PRAMEF12 PRAMEF8	6.59e-04	82	96	4	GO:1990756
GeneOntologyBiologicalProcess	ubiquitin-dependent protein catabolic process	UBR2 RC3H2 FBXL14 WDR81 CUL9 RNF213 CUL7 OTUD7B FBXL16 CCAR1 UBR3 RNF26	5.11e-05	640	98	12	GO:0006511
GeneOntologyBiologicalProcess	modification-dependent protein catabolic process	UBR2 RC3H2 FBXL14 WDR81 CUL9 RNF213 CUL7 OTUD7B FBXL16 CCAR1 UBR3 RNF26	6.02e-05	651	98	12	GO:0019941
GeneOntologyBiologicalProcess	modification-dependent macromolecule catabolic process	UBR2 RC3H2 FBXL14 WDR81 CUL9 RNF213 CUL7 OTUD7B FBXL16 CCAR1 UBR3 RNF26	6.48e-05	656	98	12	GO:0043632
GeneOntologyCellularComponent	ubiquitin ligase complex	DCAF1 UBR2 PRAMEF7 FBXL14 CUL9 PRAMEF12 CUL7 PRAMEF8 FBXL16 UBR3	6.66e-06	352	99	10	GO:0000151
GeneOntologyCellularComponent	cullin-RING ubiquitin ligase complex	DCAF1 PRAMEF7 FBXL14 CUL9 PRAMEF12 CUL7 PRAMEF8 FBXL16	7.61e-06	212	99	8	GO:0031461
Domain	ARM-type_fold	DCAF1 SMG1 USP24 CUL9 CUL7 MTOR PI4KA TERB1 EIF4G3 HEATR5B	1.16e-05	339	98	10	IPR016024
Domain	PI3/4_kinase_CS	SMG1 MTOR PI4KA	6.09e-05	15	98	3	IPR018936
Domain	-	SMG1 MTOR PI4KA	7.47e-05	16	98	3	1.10.1070.11
Domain	PI3Kc	SMG1 MTOR PI4KA	7.47e-05	16	98	3	SM00146
Domain	Cul7	CUL9 CUL7	8.15e-05	3	98	2	PF11515
Domain	Parvin	PARVB PARVG	8.15e-05	3	98	2	IPR028433
Domain	CPH_domain	CUL9 CUL7	8.15e-05	3	98	2	IPR021097
Domain	PI3/4_kinase_cat_dom	SMG1 MTOR PI4KA	1.08e-04	18	98	3	IPR000403
Domain	PI3_PI4_kinase	SMG1 MTOR PI4KA	1.08e-04	18	98	3	PF00454
Domain	PI3_4_KINASE_3	SMG1 MTOR PI4KA	1.08e-04	18	98	3	PS50290
Domain	PI3_4_KINASE_1	SMG1 MTOR PI4KA	1.08e-04	18	98	3	PS00915
Domain	PI3_4_KINASE_2	SMG1 MTOR PI4KA	1.08e-04	18	98	3	PS00916
Domain	PRAME_family	PRAMEF7 PRAMEF12 PRAMEF8	1.28e-04	19	98	3	IPR026271
Domain	GATASE_TYPE_2	ASNSD1 PPAT	2.70e-04	5	98	2	PS51278
Domain	FATC	SMG1 MTOR	2.70e-04	5	98	2	PF02260
Domain	GATase_2_dom	ASNSD1 PPAT	2.70e-04	5	98	2	IPR017932
Domain	TAS2R	TAS2R40 TAS2R39 TAS2R60	3.34e-04	26	98	3	PF05296
Domain	T2R	TAS2R40 TAS2R39 TAS2R60	3.34e-04	26	98	3	IPR007960
Domain	FAT	SMG1 MTOR	4.03e-04	6	98	2	PS51189
Domain	FATC	SMG1 MTOR	4.03e-04	6	98	2	PS51190
Domain	FATC_dom	SMG1 MTOR	4.03e-04	6	98	2	IPR003152
Domain	PIK_FAT	SMG1 MTOR	4.03e-04	6	98	2	IPR014009
Domain	FATC	SMG1 MTOR	4.03e-04	6	98	2	SM01343
Domain	HEAT_REPEAT	SMG1 MTOR EIF4G3 HEATR5B	5.01e-04	70	98	4	PS50077
Domain	ARM-like	DCAF1 SMG1 CUL9 CUL7 MTOR TERB1 HEATR5B	5.51e-04	270	98	7	IPR011989
Domain	APC_su10/DOC_dom	CUL9 CUL7	5.63e-04	7	98	2	IPR004939
Domain	ZF_UBR	UBR2 UBR3	5.63e-04	7	98	2	PS51157
Domain	DOC	CUL9 CUL7	5.63e-04	7	98	2	PS51284
Domain	zf-UBR	UBR2 UBR3	5.63e-04	7	98	2	PF02207
Domain	Znf_UBR	UBR2 UBR3	5.63e-04	7	98	2	IPR003126
Domain	ZnF_UBR1	UBR2 UBR3	5.63e-04	7	98	2	SM00396
Domain	APC10	CUL9 CUL7	5.63e-04	7	98	2	SM01337
Domain	ANAPC10	CUL9 CUL7	5.63e-04	7	98	2	PF03256
Domain	Cullin_Nedd8	CUL9 CUL7	7.48e-04	8	98	2	PF10557
Domain	Cullin_Nedd8	CUL9 CUL7	7.48e-04	8	98	2	SM00884
Domain	Cullin_neddylation_domain	CUL9 CUL7	7.48e-04	8	98	2	IPR019559
Domain	Cullin_homology	CUL9 CUL7	9.58e-04	9	98	2	IPR016158
Domain	-	DCAF1 CUL9 CUL7 MTOR TERB1 HEATR5B	1.12e-03	222	98	6	1.25.10.10
Domain	PAS_9	KCNH7 KCNH4	1.19e-03	10	98	2	PF13426
Domain	Cullin	CUL9 CUL7	1.19e-03	10	98	2	PF00888
Domain	CULLIN_2	CUL9 CUL7	1.19e-03	10	98	2	PS50069
Domain	Cullin_N	CUL9 CUL7	1.19e-03	10	98	2	IPR001373
Domain	CULLIN_1	CUL9 CUL7	1.19e-03	10	98	2	PS01256
Domain	Cyt_P450_E_grp-I	TBXAS1 CYP4B1 CYP20A1	1.69e-03	45	98	3	IPR002401
Domain	-	DCAF1 NWD1 WDR81 ZNF106 SEMA3D WDR11 PLXNB3	1.86e-03	333	98	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	DCAF1 NWD1 WDR81 ZNF106 SEMA3D WDR11 PLXNB3	1.92e-03	335	98	7	IPR015943
Domain	K_chnl_volt-dep_EAG/ELK/ERG	KCNH7 KCNH4	2.38e-03	14	98	2	IPR003938
Domain	-	TBXAS1 CYP4B1 CYP20A1	3.51e-03	58	98	3	1.10.630.10
Domain	p450	TBXAS1 CYP4B1 CYP20A1	3.51e-03	58	98	3	PF00067
Domain	Cyt_P450	TBXAS1 CYP4B1 CYP20A1	3.86e-03	60	98	3	IPR001128
Domain	Rib_L2_dom2	CUL9 CUL7	3.95e-03	18	98	2	IPR014722
Domain	-	CUL9 CUL7	3.95e-03	18	98	2	2.30.30.30
Domain	Leu-rich_rpt_Cys-con_subtyp	FBXL14 FBXL16	4.40e-03	19	98	2	IPR006553
Domain	LRR_CC	FBXL14 FBXL16	4.40e-03	19	98	2	SM00367
Domain	ZF_RING_2	UBR2 RC3H2 CUL9 RNF213 UBR3 RNF26	4.85e-03	298	98	6	PS50089
Pubmed	Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.	DCAF1 UBR2 UBR3	1.97e-06	9	101	3	17855541
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	PRAMEF7 CYP20A1 USP24 CDH23 PRAMEF12 PRAMEF8 KCNH4 GPR107 OTUD7B ZNF106 SYNJ2 MTOR VPS13A SNAPC4 PLXNB3	3.02e-06	1242	101	15	30973865
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	KCNH7 CUL9 NCKAP5 CUL7 MIA2 SYNJ2 VPS13A DKKL1	5.55e-06	329	101	8	17474147
Pubmed	SPAG5 upregulation predicts poor prognosis in cervical cancer patients and alters sensitivity to taxol treatment via the mTOR signaling pathway.	SPAG5 MTOR	8.35e-06	2	101	2	24853425
Pubmed	A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart.	CDH23 SYNJ2	8.35e-06	2	101	2	21423608
Pubmed	Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation.	MTOR NOTCH2	8.35e-06	2	101	2	34473651
Pubmed	Genetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size.	SYNJ2 PI4KA	8.35e-06	2	101	2	24077433
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	UBR2 FBXL14 RNF213 CUL7 FAM171B TBC1D10B FBXL16 WDR11 WASHC5 PI4KA VPS13A UBR3 PLK4	1.11e-05	1049	101	13	27880917
Pubmed	Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the receptor protein of CRL2Prame complex.	DCAF1 FBXL14 CUL9 CUL7	1.18e-05	48	101	4	33504946
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF7 PRAMEF12 PRAMEF8	1.57e-05	17	101	3	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF7 PRAMEF12 PRAMEF8	1.57e-05	17	101	3	37781892
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF7 PRAMEF12 PRAMEF8	1.88e-05	18	101	3	23894331
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF7 PRAMEF12 PRAMEF8	1.88e-05	18	101	3	12890732
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF7 PRAMEF12 PRAMEF8	1.88e-05	18	101	3	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF7 PRAMEF12 PRAMEF8	1.88e-05	18	101	3	14675769
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF7 PRAMEF12 PRAMEF8	1.88e-05	18	101	3	39181896
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF7 PRAMEF12 PRAMEF8	2.23e-05	19	101	3	28604677
Pubmed	NOTCH knockdown affects the proliferation and mTOR signaling of leukemia cells.	MTOR NOTCH2	2.50e-05	3	101	2	24122995
Pubmed	SPAG5 promotes proliferation and suppresses apoptosis in bladder urothelial carcinoma by upregulating Wnt3 via activating the AKT/mTOR pathway and predicts poorer survival.	SPAG5 MTOR	2.50e-05	3	101	2	29662193
Pubmed	Expression of a mutant p193/CUL7 molecule confers resistance to MG132- and etoposide-induced apoptosis independent of p53 or Parc binding.	CUL9 CUL7	2.50e-05	3	101	2	17229476
Pubmed	Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development.	CUL9 CUL7	2.50e-05	3	101	2	15964813
Pubmed	The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53.	CUL9 CUL7	2.50e-05	3	101	2	17298945
Pubmed	MicroRNA-18a promotes cancer progression through SMG1 suppression and mTOR pathway activation in nasopharyngeal carcinoma.	SMG1 MTOR	2.50e-05	3	101	2	31659158
Pubmed	A novel p53-binding domain in CUL7.	CUL9 CUL7	2.50e-05	3	101	2	16875676
Pubmed	Genomic organization and expression profile of the parvin family of focal adhesion proteins in mice and humans.	PARVB PARVG	2.50e-05	3	101	2	11722847
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF7 PRAMEF12 PRAMEF8	2.61e-05	20	101	3	26694250
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF7 PRAMEF12 PRAMEF8	2.61e-05	20	101	3	16580637
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF7 PRAMEF12 PRAMEF8	2.61e-05	20	101	3	21425410
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF7 PRAMEF12 PRAMEF8	3.52e-05	22	101	3	31729367
Pubmed	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.	TAS2R40 TAS2R39 TAS2R60	3.52e-05	22	101	3	12734386
Pubmed	The molecular receptive ranges of human TAS2R bitter taste receptors.	TAS2R40 TAS2R39 TAS2R60	4.04e-05	23	101	3	20022913
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF7 PRAMEF12 PRAMEF8	4.04e-05	23	101	3	19480014
Pubmed	[Association of single nucleotide polymorphisms of cytochrome P450 gene with susceptibility to gout in ethnic Han males from coastal regions of Shandong province].	TBXAS1 CYP4B1	4.99e-05	4	101	2	26252103
Pubmed	Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol.	TAS2R40 TAS2R60	4.99e-05	4	101	2	23632330
Pubmed	Tex19.1 inhibits the N-end rule pathway and maintains acetylated SMC3 cohesin and sister chromatid cohesion in oocytes.	UBR2 UBR3	4.99e-05	4	101	2	32232464
Pubmed	Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells.	F10 MTOR	4.99e-05	4	101	2	18612547
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF7 PRAMEF12 PRAMEF8	5.22e-05	25	101	3	37451217
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF7 PRAMEF12 PRAMEF8	5.22e-05	25	101	3	12620990
Pubmed	Receptors for bitter and sweet taste.	TAS2R40 TAS2R39 TAS2R60	5.22e-05	25	101	3	12139982
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF7 PRAMEF12 PRAMEF8	5.89e-05	26	101	3	18500982
Pubmed	Molecular mechanisms of bitter and sweet taste transduction.	TAS2R40 TAS2R39 TAS2R60	5.89e-05	26	101	3	11696554
Pubmed	Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.	TAS2R40 TAS2R39 TAS2R60	6.61e-05	27	101	3	12581520
Pubmed	Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.	TAS2R40 TAS2R39 TAS2R60	7.39e-05	28	101	3	15744053
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	PRAMEF7 PRAMEF12 PRAMEF8	7.39e-05	28	101	3	25089626
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	DCAF1 SPAG5 ZNF106 WASHC5 SCML1 EIF4G3	7.79e-05	242	101	6	34011540
Pubmed	Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells.	SPAG5 MTOR	8.30e-05	5	101	2	23953116
Pubmed	CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity.	CUL9 CUL7	8.30e-05	5	101	2	24793696
Pubmed	The focal adhesion protein β-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load.	PARVB PARVG	8.30e-05	5	101	2	35688156
Pubmed	PARC and CUL7 form atypical cullin RING ligase complexes.	CUL9 CUL7	8.30e-05	5	101	2	17332328
Pubmed	Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.	PRAMEF7 PRAMEF12 PRAMEF8	9.12e-05	30	101	3	38786026
Pubmed	Adaptive diversification of bitter taste receptor genes in Mammalian evolution.	TAS2R40 TAS2R39 TAS2R60	9.12e-05	30	101	3	12679530
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	PRAMEF7 WDR81 NCKAP5 PRAMEF12 TMC4 PRAMEF8 ZNF106	9.45e-05	363	101	7	14691545
Pubmed	LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.	PRAMEF7 PRAMEF12 PRAMEF8	1.11e-04	32	101	3	37889087
Pubmed	Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.	UBR2 FBXL14 RNF213 FBXL16	1.13e-04	85	101	4	19028597
Pubmed	Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily.	PARVB PARVG	1.24e-04	6	101	2	11171322
Pubmed	Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway.	UBR2 UBR3	1.24e-04	6	101	2	10805755
Pubmed	eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy.	MTOR EIF4G3	1.24e-04	6	101	2	18426977
Pubmed	Evolution of bitter taste receptors in humans and apes.	TAS2R40 TAS2R39 TAS2R60	1.33e-04	34	101	3	15496549
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	PRAMEF7 PRAMEF12 PRAMEF8	1.45e-04	35	101	3	19389355
Pubmed	The rapid activation of protein synthesis by growth hormone requires signaling through mTOR.	CSHL1 MTOR	1.74e-04	7	101	2	17284572
Pubmed	SPAG5-AS1 inhibited autophagy and aggravated apoptosis of podocytes via SPAG5/AKT/mTOR pathway.	SPAG5 MTOR	1.74e-04	7	101	2	31957155
Pubmed	microRNA-449a reduces growth hormone-stimulated senescent cell burden through PI3K-mTOR signaling.	CSHL1 MTOR	1.74e-04	7	101	2	36976763
Pubmed	TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.	OTUD7B MTOR	1.74e-04	7	101	2	28489822
Pubmed	The collagen derived dipeptide hydroxyprolyl-glycine promotes C2C12 myoblast differentiation and myotube hypertrophy.	SLC15A2 MTOR	1.74e-04	7	101	2	27553280
Pubmed	Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins.	UBR2 UBR3	1.74e-04	7	101	2	21816346
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	UBR2 CUL9 RNF213 UBR3	1.74e-04	95	101	4	29643511
Pubmed	Proteomic analysis of mammalian primary cilia.	EVC2 WDR11	2.31e-04	8	101	2	22326026
Pubmed	A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.	SMG1 MTOR	2.31e-04	8	101	2	20810650
Pubmed	Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells.	RC3H2 MTOR	2.31e-04	8	101	2	29246441
Pubmed	High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism.	RASA1 NOTCH2	2.31e-04	8	101	2	15068794
Pubmed	Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.	TBXAS1 CYP4B1 CYP20A1	2.89e-04	44	101	3	12745259
Pubmed	Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.	PRAMEF7 PRAMEF12 PRAMEF8	3.30e-04	46	101	3	17287250
Pubmed	Tel2 regulates the stability of PI3K-related protein kinases.	SMG1 MTOR	3.70e-04	10	101	2	18160036
Pubmed	Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.	KCNH7 KCNH4	3.70e-04	10	101	2	26503718
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	UBR2 USP24 CUL9 CUL7 CCAR1	3.96e-04	212	101	5	33853758
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	PRAMEF7 PRAMEF12 PRAMEF8	4.22e-04	50	101	3	31806660
Pubmed	Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.	SMG1 MTOR	4.51e-04	11	101	2	20427287
Pubmed	Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.	CUL9 CUL7	4.51e-04	11	101	2	31570706
Pubmed	HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1.	UBR2 UBR3	5.41e-04	12	101	2	17360488
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	CUL9 CUL7 SYNJ2 PLXNB3	5.75e-04	130	101	4	12421765
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	NWD1 VPS50 PARVG ZNF106 KIAA0825 CCAR1 IGLL1	6.32e-04	497	101	7	36774506
Pubmed	Identification and characterization of human taste receptor genes belonging to the TAS2R family.	TAS2R40 TAS2R60	6.38e-04	13	101	2	12584440
Pubmed	ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation.	PRAMEF7 PRAMEF12 PRAMEF8	6.53e-04	58	101	3	31598710
Pubmed	Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.	USP24 MTOR PI4KA	6.53e-04	58	101	3	31067491
Pubmed	An abundance of X-linked genes expressed in spermatogonia.	PRAMEF7 PRAMEF12 PRAMEF8	6.87e-04	59	101	3	11279525
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	UBR2 SLC39A1 RNF213 DIPK2A SPAG5 GPR107 MIA2 TMEM245 ALG3 EIF4G3 NOTCH2	7.41e-04	1201	101	11	35696571
Pubmed	Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion.	CUL9 CUL7	7.43e-04	14	101	2	22653443
Pubmed	Platelet storage pool deficiency associated with inherited abnormalities of the inner ear in the mouse pigment mutants muted and mocha.	CDH23 PMEL	7.43e-04	14	101	2	1912584
Pubmed	UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.	DCAF1 UBR2 WDR11	7.94e-04	62	101	3	18775313
Pubmed	FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation.	MTOR NOTCH2	8.55e-04	15	101	2	31285543
Pubmed	CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability.	SMG1 MTOR	8.55e-04	15	101	2	20864032
Pubmed	Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.	CYP4B1 CYP20A1 SLC15A2	9.52e-04	66	101	3	19898482
Pubmed	Modifier genes and protective alleles in humans and mice.	CDH23 NOTCH2	9.76e-04	16	101	2	12787792
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	SEMA3D PLXNB3	1.10e-03	17	101	2	17626059
Pubmed	Association analyses identify three susceptibility Loci for vitiligo in the Chinese Han population.	CDH23 PMEL	1.10e-03	17	101	2	22951725
Pubmed	Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.	MTOR PI4KA	1.10e-03	17	101	2	25327288
Pubmed	Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.	TBXAS1 CYP4B1 CYP20A1	1.13e-03	70	101	3	15128046
Pubmed	Integrin-linked kinase is an adaptor with essential functions during mouse development.	PARVB MTOR	1.24e-03	18	101	2	19829382
Pubmed	CRL7SMU1 E3 ligase complex-driven H2B ubiquitylation functions in sister chromatid cohesion by regulating SMC1 expression.	DCAF1 CUL7	1.24e-03	18	101	2	29507117
Pubmed	Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.	TERB1 GPAT2	1.38e-03	19	101	2	17660561
Cytoband	12q13-q14	MYO1A PMEL	7.15e-05	6	101	2	12q13-q14
Cytoband	1p36.21	PRAMEF7 PRAMEF12 PRAMEF8	3.73e-04	63	101	3	1p36.21
Cytoband	6p21.1	UBR2 CUL9 CUL7	7.51e-04	80	101	3	6p21.1
Cytoband	22q11.21	PI4KAP2 PI4KAP1 PI4KA	1.93e-03	111	101	3	22q11.21
GeneFamily	Parvins	PARVB PARVG	4.55e-05	3	71	2	673
GeneFamily	PRAME family	PRAMEF7 PRAMEF12 PRAMEF8	1.11e-04	24	71	3	686
GeneFamily	Ubiquitin protein ligase E3 component n-recognins	UBR2 UBR3	3.15e-04	7	71	2	785
GeneFamily	Cullins	CUL9 CUL7	4.19e-04	8	71	2	1032
GeneFamily	Taste 2 receptors	TAS2R40 TAS2R39 TAS2R60	4.79e-04	39	71	3	1162
GeneFamily	F-box and leucine rich repeat proteins	FBXL14 FBXL16	3.04e-03	21	71	2	558
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBXAS1 CDH23 PARVB LRRC70 F10 OTUD7B VPS13A CNR2	7.24e-09	177	101	8	84591e28482ab62a5ef41e61043eb64912766356
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBXAS1 CDH23 PARVB LRRC70 F10 OTUD7B VPS13A CNR2	7.24e-09	177	101	8	4bc100062891d07cacd10ffba38966cc6302c92f
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBXAS1 CDH23 PARVB LRRC70 F10 OTUD7B VPS13A CNR2	7.24e-09	177	101	8	9f3a2adb9cd4f0a059afc87b6e377a9702154bb1
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 GPR182 CYP20A1 CUL7 SEMA3D CLCA1 SYNJ2	2.20e-07	185	101	7	bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell	Club-club-2\|World / Class top	CYP4B1 ESPNL WFDC1 SEMA3D CLCA1 SLC15A2	2.19e-06	166	101	6	56f11efb6b686b3ee2c34a051f626e3d761b5112
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBXAS1 CDH23 PARVB LRRC70 F10 OTUD7B	3.27e-06	178	101	6	9e1f2596fcea5b79cc50b58d83706bb8605e224f
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBXAS1 CDH23 PARVB LRRC70 F10 OTUD7B	3.27e-06	178	101	6	aa659bd283c4dfbe292cd8698bbf6b1999ca3314
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBXAS1 CDH23 PARVB LRRC70 F10 OTUD7B	3.27e-06	178	101	6	bf1d273802a4f42e52ea1bd2a0cae2039559c093
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	UBR2 SMG1 RNPC3 USP24 RNF213 VPS13A	6.21e-06	199	101	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Rassf10\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NCKAP5 PARVB PMEL SEMA3D PLXNB3	7.69e-06	119	101	5	ec3af1253f03b3ec403f73243237acf08ad56789
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DCAF1 PARVG TLCD2 MTOR DKKL1	4.92e-05	175	101	5	bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCell	(03)_Secretory\|World / shred by cell type and Timepoint	CYP4B1 WFDC1 CLCA1 SLC15A2 NOTCH2	5.06e-05	176	101	5	cb7b1945788196ca79007f0768b6576ec885a0e5
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Drd1_(Deep_layer_pyramidal_cells)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	RC3H2 MYO1A SAMD8 KCNH4 WDR11	5.06e-05	176	101	5	3c76a5c4ca2b378667cb155fbb9675519572b35d
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBXAS1 NWD1 PARVB LRRC70 CLCA1	5.34e-05	178	101	5	63f5880a5b514e20ef2c07a6a9cb8df34e6cede5
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBXAS1 NWD1 PARVB LRRC70 CLCA1	5.34e-05	178	101	5	82c84f8b8a7e6a3d3be3351b348a37143279c100
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBXAS1 NWD1 PARVB LRRC70 CLCA1	5.34e-05	178	101	5	cb91558469ae0748106fb0b6d702edb0ff21a884
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBXAS1 PARVB LRRC70 VPS13A CNR2	5.63e-05	180	101	5	ca2a35bfb67347e47f511589a3d0f763e6664634
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBXAS1 PARVB LRRC70 VPS13A CNR2	5.63e-05	180	101	5	4e9e8cde2919610c4ac0025b1c9819808048bc1d
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBXAS1 PARVB LRRC70 VPS13A CNR2	5.63e-05	180	101	5	466381bf93c3da6a2a241daadb68e9aad2964eae
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPR182 PARVB SEMA3D SNAPC4 GPAT2	5.93e-05	182	101	5	f231e86524b628e6e11ac33d5c34be99d454a92a
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 ZNF106 MIA2 IGLL1 EIF4G3	6.41e-05	185	101	5	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NWD1 CYP4B1 GPR182 SEMA3D CNR2	6.91e-05	188	101	5	0aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NWD1 CYP4B1 GPR182 SEMA3D CNR2	7.27e-05	190	101	5	a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NWD1 CYP4B1 GPR182 SEMA3D CNR2	7.27e-05	190	101	5	25525fee1da8a808034d9c916159fd0b6b26bce8
ToppCell	proximal-Hematologic-Platelet/Megakaryocyte\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MYO1A PI4KAP2 KIAA0825 PI4KA PLK4	7.64e-05	192	101	5	522d1bb15edf1d6006b80289bd3baadb99584ae8
ToppCell	proximal-3-Hematologic-Platelet/Megakaryocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MYO1A PI4KAP2 KIAA0825 PI4KA PLK4	7.64e-05	192	101	5	f5f83dec37dff32a0c471cb05d23d13b0b0ad0c9
ToppCell	droplet-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 GPR182 WFDC1 NCKAP5 PARVB	7.64e-05	192	101	5	42e4dafbe3e8b4a3c25d594f06b95430a1dd8b28
ToppCell	proximal-Hematologic-Platelet/Megakaryocyte-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MYO1A PI4KAP2 KIAA0825 PI4KA PLK4	7.64e-05	192	101	5	57899a905ca3e336bb7f31edc6418a2546b9891a
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP4B1 GPR182 WFDC1 NCKAP5 PARVB	7.64e-05	192	101	5	6b69bb8fab9b470850eba1a070a500435ec233cd
ToppCell	droplet-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 GPR182 WFDC1 NCKAP5 PARVB	7.82e-05	193	101	5	7cff1e859b296b1032eebcfc0f99a504f3bda2c9
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP4B1 GPR182 WFDC1 NCKAP5 PARVB	7.82e-05	193	101	5	1b6317b740cad2439f08b9e9895426d861e7a161
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP4B1 GPR182 WFDC1 NCKAP5 PARVB	7.82e-05	193	101	5	f5861cfa4401b476229a7c61cd64abad79a4bbfc
ToppCell	droplet-Lung-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP4B1 GPR182 WFDC1 NCKAP5 PARVB	7.82e-05	193	101	5	95c9c63bddfed1a84393ccd3578cfe65bc0c1c05
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Dendritic_cell-DC_2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBXAS1 TARM1 NDST2 SIRPB2 PARVG	8.41e-05	196	101	5	8862964090f9a679a548103bfbb12e91295aae62
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 RNPC3 USP24 RNF213 VPS13A	8.62e-05	197	101	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Dendritic_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBXAS1 TARM1 NDST2 SIRPB2 PARVG	8.62e-05	197	101	5	e0fc098bfb5a8b7824ae339f3adda30f78360d0b
Disease	chromosome 22q11.2 deletion syndrome, distal (implicated_via_orthology)	PI4KAP2 PRODH2 PI4KA	1.04e-05	14	92	3	DOID:0060413 (implicated_via_orthology)
Disease	colonic neoplasm, overall survival	ISM1 PARVG	8.54e-04	14	92	2	EFO_0000638, EFO_0004288
Disease	Neoplasm of uncertain or unknown behavior of bladder	MTOR NOTCH2	9.83e-04	15	92	2	C0496930
Disease	Benign neoplasm of bladder	MTOR NOTCH2	9.83e-04	15	92	2	C0154017
Disease	Carcinoma in situ of bladder	MTOR NOTCH2	9.83e-04	15	92	2	C0154091
Disease	Carcinoma of bladder	MTOR NOTCH2	1.42e-03	18	92	2	C0699885
Disease	sciatic neuropathy (implicated_via_orthology)	MTOR CNR2	2.33e-03	23	92	2	DOID:11446 (implicated_via_orthology)
Disease	information processing speed	CDH23 NCKAP5 TMEM245	2.41e-03	85	92	3	EFO_0004363
Disease	migraine disorder, Headache	MYO1A GPR182 RNF213	2.49e-03	86	92	3	HP_0002315, MONDO_0005277
Disease	Depressive Symptoms	NCKAP5 SYNJ2	2.98e-03	26	92	2	C0086132

Protein segments in the cluster

Peptide	Gene	Start	Entry
LVALTLVAGKLTHLI	ARSL	206	P51690
TLGLHLSRAQVKKLL	CCAR1	951	Q8IX12
THLLRLLVLGLIELS	ALG3	381	Q92685
KSNLELLHISLLLIE	CSHL1	101	Q14406
IGLLNSTAHLLITIL	CDH23	2046	Q9H251
VRLAKTLGLVLAVLL	CNR2	241	P34972
HLKGTGELTRALLVL	PRODH2	106	Q9UF12
LLGHKTVTVLRLLGT	NWD1	361	Q149M9
GRHLTLNLLSKEIEL	RC3H2	1021	Q9HBD1
LLSTLHLLVALAKRF	PARVG	136	Q9HBI0
LLASILLRIFLHEKL	RASA1	751	P20936
THLLKGALLFITIAL	GPR107	336	Q5VW38
LASVILSLEVKLHLL	OTUD7B	411	Q6GQQ9
LRALGTLLHTNLRIK	NOTCH2	1566	Q04721
LLLIRNHLISKGLGE	DCAF1	851	Q9Y4B6
RSLSLLLKGVHGLVQ	ESPNL	601	Q6ZVH7
KASLLALVLGHILLN	MAGEE2	176	Q8TD90
TLLHHDGLLLRILLK	KIAA0825	816	Q8IV33
HVLSLALAGLLLLLV	NTSR2	71	O95665
SRILLLTKGHVILTD	MYO1A	911	Q9UBC5
TLIGLLKTARLLRLV	KCNH7	521	Q9NS40
RRHLLVLLLLLSTLV	DKKL1	11	Q9UK85
LLNSKLFLLTLIHTL	PLXNB3	1376	Q9ULL4
LLLIALVLSAKLGHF	CSTL1	11	Q9H114
VLSCILHLLGKGTLR	CUL7	1621	Q14999
LLKELGAFHITIALL	MS4A10	56	Q96PG2
KLLTLGLSLLHADVV	PI4KA	1351	P42356
PRFKLLTLGLSLLHA	PI4KAP1	91	Q8N8J0
SLVHLLKTVRLLRLL	KCNH4	331	Q9UQ05
IIALLLKNLTSSGHL	EVC2	406	Q86UK5
KHISRGLTGLRLLNL	FBXL14	221	Q8N1E6
RLKSATHLVILLIAL	BBS9	726	Q3SYG4
LLLLLHKEILGCSSV	LRRC70	21	Q7Z2Q7
GKNLVAILHLLVSLA	PARVB	176	Q9HBI1
LLRHTVGLSKLSLEL	PRAMEF12	396	O95522
LLLLGLAVVTHGLLR	IGLL1	26	P15814
LIGVELLSVLHRLLL	HEATR5B	1636	Q9P2D3
RLSRSLKLAALGSLL	DIPK2A	11	Q8NDZ4
LLSTHKTLLDGILLP	GPAT2	201	Q6NUI2
IGHSLESDLLALKLI	REXO1L1P	581	Q8IX06
VIHKLGITLVSLLLF	MBOAT1	241	Q6ZNC8
KLLLRLAAVELGLTA	ASNSD1	581	Q9NWL6
LLSCLLVRILKAHGE	CUL9	1871	Q8IWT3
ILVLGFLKLIHLLLR	CYP4B1	21	P13584
SKLELIDLLARLSIH	FRY	621	Q5TBA9
VLLSVLVKRLHLLSV	CYP20A1	421	Q6UW02
HLVLLSASLAGLLLL	F10	6	P00742
LLRHTVGLSKLSLEL	PRAMEF8	396	Q5VWM4
VHTVLSLIGLSLIAL	SLC15A2	141	Q16348
LTLSELKRLFNLHLA	POLR3E	576	Q9NVU0
RAGVLLSEILHLLCK	EIF4G3	1351	O43432
LLGLLLLTLHITVLR	ISM1	11	B1AKI9
TLLLGLAVVLLKARL	FAM171B	11	Q6P995
VHRILLLAISLTKCL	MIA2	6	Q96PC5
LALAHKTLVLLLGVD	MTOR	1666	P42345
KHLLALGSLRLLSLA	FBXL16	416	Q8N461
LTATLLILSLKRHTL	TAS2R39	226	P59534
LAATLLILSLKRHTL	TAS2R40	211	P59535
LITSLGRHRKKALLT	TAS2R60	216	P59551
ALLLLTSDVLLKHLG	SCML1	291	Q9UN30
SKELISLLHLSLLHL	SPAG5	511	Q96R06
ALEVLHLQLKTLGLS	SYNJ2	401	O15056
LLVLLLHKHRSILLR	SAMD8	216	Q96LT4
LLLQKLHSRLLDLSS	NCKAP5	266	O14513
VTLLLLTLHGTHISL	GPR182	276	O15218
HFSIILNLLGILLKK	SMG1	706	Q96Q15
LTSLLHLGRGVLLSL	RNF26	51	Q9BY78
KRCLLHLAVIGALLA	PMEL	6	P40967
PRFKLLTLGLSLLHA	PI4KAP2	91	A4QPH2
GILHRDLTLSNLLLT	PLK4	131	O00444
RLLLGAKDHIFLLSL	SEMA3D	81	O95025
LILHLLEGALSNSLI	CLCA1	11	A8K7I4
LLLGVLSLLVESHHL	TMEM95	156	Q3KNT9
LLRHTVGLSKLSLEL	PRAMEF7	396	Q5VXH5
LLLRRCLTLGSLGHK	RNF213	1876	Q63HN8
LIRLLTHLALLLGAS	RNF213	4581	Q63HN8
IRALCLLLLLLHAGS	WFDC1	16	Q9HC57
LLIGLLKSLRTIKTL	VPS50	166	Q96JG6
VLGLKAITLAALLLA	SIRPB2	296	Q5JXA9
GVRLGLLEVKLTLLH	TBXAS1	481	P24557
FSLLLCSLALLHRKG	ZPLD1	386	Q8TCW7
LVLGLLTLLKQFHSR	WASHC5	1076	Q12768
LLLDLGHLKVTSKSR	VPS13A	671	Q96RL7
ALTRLHQLKLLGHTL	RNPC3	81	Q96LT9
LLLELNSACLHLRKL	TLCD2	136	A6NGC4
CLALLLHKGILAVSL	SLC39A1	211	Q9NY26
LHKGILAVSLSLRLL	SLC39A1	216	Q9NY26
LLLILHRSVSGLKQT	TMC4	266	Q7Z404
LRKKLLRHGIGLSTS	PPAT	131	Q06203
RLQLSHDLLGILLLK	NMB	81	P08949
LHRLILLLIAFSLGS	NDST2	16	P52849
ALVLLRHTLGSVEKL	TBC1D10B	556	Q4KMP7
IGTLLLALLLTAKVH	TMEM245	471	Q9H330
ADNILLAGHLRLIKT	USP24	1561	Q9UPU5
LAGHLRLIKTLLSLC	USP24	1566	Q9UPU5
LKSLHQLLEVLLALL	USP24	2256	Q9UPU5
LTFLVILLSLRLHLG	UBR3	766	Q6ZT12
LRALSGLLLHKKALE	SNAPC4	1311	Q5SXM2
ILREVHLKFLLTGLL	WDR11	446	Q9BZH6
RLLAGLHVLLSKSEV	UBR2	616	Q8IWV8
IVSKLLALLLHESLD	TERB1	296	Q8NA31
LLLRTLEGHSKTILC	ZNF106	1691	Q9H2Y7
LTSLALLPTKRHLLL	WDR81	1916	Q562E7
HSVASALLGVLLLVL	ZDHHC1	181	Q8WTX9
RSDVLLLLVTGHLSK	TARM1	111	B6A8C7