Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	scaffold protein binding	NLGN4X NLGN4Y KIF1B GRIA1 NOS3	1.12e-05	93	63	5	GO:0097110
GeneOntologyBiologicalProcess	territorial aggressive behavior	NLGN4X NLGN4Y	2.75e-05	3	63	2	GO:0002124
GeneOntologyBiologicalProcess	male courtship behavior	NLGN4X NLGN4Y	5.49e-05	4	63	2	GO:0008049
GeneOntologyCellularComponent	symmetric, GABA-ergic, inhibitory synapse	NLGN4X NLGN4Y	5.69e-05	4	65	2	GO:0098983
MousePheno	abnormal mineral level	MYO7A KIF1B CYP27B1 MTMR3 SCUBE3 BAZ1B GRIA1 UBE3C NOS3 MYSM1 HYAL2 EPB42	4.69e-05	1066	42	12	MP:0000192
MousePheno	abnormal mineral homeostasis	MYO7A KIF1B CYP27B1 MTMR3 SCUBE3 BAZ1B GRIA1 UBE3C NOS3 MYSM1 HYAL2 EPB42	5.14e-05	1076	42	12	MP:0005636
MousePheno	anovulation	KISS1R CYP27B1 NOS3	1.29e-04	33	42	3	MP:0008869
MousePheno	absent alveolar lamellar bodies	ABCA12 NOS3	1.31e-04	6	42	2	MP:0010814
MousePheno	increased mineral level	MYO7A KIF1B MTMR3 SCUBE3 BAZ1B GRIA1 MYSM1 HYAL2 EPB42	1.33e-04	668	42	9	MP:0014535
MousePheno	abnormal blood urea nitrogen level	KISS1R MYO7A KIF1B SCAPER SCUBE3 GRIA1 NOS3	1.42e-04	389	42	7	MP:0005265
MousePheno	increased circulating alkaline phosphatase level	FCGBP KISS1R CYP27B1 MTMR3 GRIA1 UBE3C MYSM1 MPG	1.45e-04	526	42	8	MP:0002968
MousePheno	abnormal ion homeostasis	MYO7A KIF1B CYP27B1 MTMR3 SCUBE3 BAZ1B GRIA1 UBE3C NOS3 MYSM1 HYAL2 EPB42	1.89e-04	1232	42	12	MP:0001765
Domain	NLGN4	NLGN4X NLGN4Y	1.12e-05	2	63	2	IPR030025
Domain	Nucleoside_tran	SLC29A1 SLC29A4	6.69e-05	4	63	2	PF01733
Domain	Eqnu_transpt	SLC29A1 SLC29A4	6.69e-05	4	63	2	IPR002259
Domain	Nlgn	NLGN4X NLGN4Y	1.11e-04	5	63	2	IPR000460
Domain	TSP_3	THBS1 THBS2	1.11e-04	5	63	2	PF02412
Domain	TSP3	THBS1 THBS2	1.11e-04	5	63	2	PS51234
Domain	TSP_CTER	THBS1 THBS2	1.11e-04	5	63	2	PS51236
Domain	-	THBS1 THBS2	1.11e-04	5	63	2	4.10.1080.10
Domain	Thrombospondin_C	THBS1 THBS2	1.11e-04	5	63	2	IPR008859
Domain	TSP_C	THBS1 THBS2	1.11e-04	5	63	2	PF05735
Domain	Thrombospondin_3_rpt	THBS1 THBS2	1.11e-04	5	63	2	IPR017897
Domain	Thrombospondin_3-like_rpt	THBS1 THBS2	1.11e-04	5	63	2	IPR003367
Domain	TSP_type-3_rpt	THBS1 THBS2	1.11e-04	5	63	2	IPR028974
Domain	VWC	THBS1 THBS2 FCGBP	2.84e-04	38	63	3	SM00214
Domain	HATC_C_dom	ZBED4 ZNF862	3.09e-04	8	63	2	IPR008906
Domain	Dimer_Tnp_hAT	ZBED4 ZNF862	3.09e-04	8	63	2	PF05699
Domain	VWF_dom	THBS1 THBS2 FCGBP	3.82e-04	42	63	3	IPR001007
Domain	PH_dom-spectrin-type	PSD PSD4	3.97e-04	9	63	2	IPR001605
Domain	EGF_3	THBS2 SCUBE3	7.23e-04	12	63	2	PF12947
Domain	EGF_dom	THBS2 SCUBE3	7.23e-04	12	63	2	IPR024731
Domain	Carboxylesterase_B_CS	NLGN4X NLGN4Y	8.53e-04	13	63	2	IPR019819
Domain	CARBOXYLESTERASE_B_2	NLGN4X NLGN4Y	9.93e-04	14	63	2	PS00941
Domain	COesterase	NLGN4X NLGN4Y	9.93e-04	14	63	2	PF00135
Domain	CarbesteraseB	NLGN4X NLGN4Y	9.93e-04	14	63	2	IPR002018
Domain	-	PSD PSD4	1.14e-03	15	63	2	1.10.1000.11
Domain	Sec7	PSD PSD4	1.14e-03	15	63	2	PF01369
Domain	Sec7_alpha_orthog	PSD PSD4	1.14e-03	15	63	2	IPR023394
Domain	EGF	THBS1 THBS2 FCGBP SCUBE3 HYAL2	1.17e-03	235	63	5	SM00181
Domain	Sec7	PSD PSD4	1.30e-03	16	63	2	SM00222
Domain	SEC7	PSD PSD4	1.30e-03	16	63	2	PS50190
Domain	Sec7_dom	PSD PSD4	1.30e-03	16	63	2	IPR000904
Domain	EGF-like_dom	THBS1 THBS2 FCGBP SCUBE3 HYAL2	1.52e-03	249	63	5	IPR000742
Domain	IQ	MYH10 MYO7A UBE3C	1.78e-03	71	63	3	PF00612
Domain	-	PSD MYO7A KIF1B MTMR3 FAM43B PSD4	2.01e-03	391	63	6	2.30.29.30
Domain	IQ	MYH10 MYO7A UBE3C	2.59e-03	81	63	3	SM00015
Domain	TSPN	THBS1 THBS2	2.71e-03	23	63	2	SM00210
Domain	EGF_CA	THBS1 THBS2 SCUBE3	3.07e-03	86	63	3	PF07645
Domain	PH_dom-like	PSD MYO7A KIF1B MTMR3 FAM43B PSD4	3.08e-03	426	63	6	IPR011993
Domain	IQ_motif_EF-hand-BS	MYH10 MYO7A UBE3C	3.49e-03	90	63	3	IPR000048
Domain	IQ	MYH10 MYO7A UBE3C	3.82e-03	93	63	3	PS50096
Domain	VWC	THBS1 THBS2	4.00e-03	28	63	2	PF00093
Domain	VWFC_1	THBS1 THBS2	6.55e-03	36	63	2	PS01208
Domain	Myosin_head_motor_dom	MYH10 MYO7A	7.28e-03	38	63	2	IPR001609
Domain	VWFC_2	THBS1 THBS2	7.28e-03	38	63	2	PS50184
Domain	MYOSIN_MOTOR	MYH10 MYO7A	7.28e-03	38	63	2	PS51456
Domain	Myosin_head	MYH10 MYO7A	7.28e-03	38	63	2	PF00063
Domain	MYSc	MYH10 MYO7A	7.28e-03	38	63	2	SM00242
Domain	EGF_CA	THBS1 THBS2 SCUBE3	8.12e-03	122	63	3	SM00179
Domain	EGF_3	THBS1 THBS2 SCUBE3 HYAL2	8.15e-03	235	63	4	PS50026
Pubmed	Distinct spatiotemporal expression of EFA6D, a guanine nucleotide exchange factor for ARF6, among the EFA6 family in mouse brain.	PSD GRIA1 PSD4	7.41e-07	10	65	3	16707115
Pubmed	Induced thrombospondin expression in the mouse pancreas during pancreatic injury.	THBS1 THBS2	3.44e-06	2	65	2	16181801
Pubmed	Immunochemical analysis of the structure of the signature domains of thrombospondin-1 and thrombospondin-2 in low calcium concentrations.	THBS1 THBS2	3.44e-06	2	65	2	17620335
Pubmed	Human cytomegalovirus infection modulates thrombospondins 1 and 2 in primary fetal astrocytes.	THBS1 THBS2	3.44e-06	2	65	2	23660684
Pubmed	Increased excitatory connectivity and epileptiform activity in thrombospondin1/2 knockout mice following cortical trauma.	THBS1 THBS2	3.44e-06	2	65	2	39122122
Pubmed	Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts.	THBS1 THBS2	3.44e-06	2	65	2	34425286
Pubmed	Thrombospondin-1 (TSP1)-null and TSP2-null mice exhibit lower intraocular pressures.	THBS1 THBS2	3.44e-06	2	65	2	22930728
Pubmed	Modulation of thrombospondin expression during differentiation of embryonal carcinoma cells.	THBS1 THBS2	3.44e-06	2	65	2	8126073
Pubmed	THBS1 and THBS2 Enhance the In Vitro Proliferation, Adhesion, Migration and Invasion of Intrahepatic Cholangiocarcinoma Cells.	THBS1 THBS2	3.44e-06	2	65	2	38339060
Pubmed	Unusually rapid evolution of Neuroligin-4 in mice.	NLGN4X NLGN4Y	3.44e-06	2	65	2	18434543
Pubmed	Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Temporal Lobe Epilepsy Before and After Surgery.	THBS1 THBS2	3.44e-06	2	65	2	33372257
Pubmed	An association study of thrombospondin 1 and 2 SNPs with coronary artery disease and myocardial infarction among South Indians.	THBS1 THBS2	3.44e-06	2	65	2	21762961
Pubmed	Restricted localization of thrombospondin-2 protein during mouse embryogenesis: a comparison to thrombospondin-1.	THBS1 THBS2	3.44e-06	2	65	2	9694593
Pubmed	Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.	NLGN4X NLGN4Y	3.44e-06	2	65	2	23183221
Pubmed	Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.	NLGN4X NLGN4Y	3.44e-06	2	65	2	24855039
Pubmed	The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice.	THBS1 THBS2	3.44e-06	2	65	2	12213711
Pubmed	Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.	NLGN4X NLGN4Y	3.44e-06	2	65	2	37001827
Pubmed	Thrombospondin expression in aldosterone-producing adenomas.	THBS1 THBS2	3.44e-06	2	65	2	12358136
Pubmed	Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out Mice.	NLGN4X NLGN4Y	3.44e-06	2	65	2	37080762
Pubmed	A second, expressed thrombospondin gene (Thbs2) exists in the mouse genome.	THBS1 THBS2	3.44e-06	2	65	2	1712771
Pubmed	Expression of thrombospondin-1 in ischemia-induced retinal neovascularization.	THBS1 THBS2	3.44e-06	2	65	2	10027393
Pubmed	Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex.	NLGN4X NLGN4Y	3.44e-06	2	65	2	29106499
Pubmed	Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.	NLGN4X NLGN4Y	3.44e-06	2	65	2	26456829
Pubmed	Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro.	NLGN4X NLGN4Y	3.44e-06	2	65	2	24104404
Pubmed	A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y.	NLGN4X NLGN4Y	3.44e-06	2	65	2	32243781
Pubmed	Contribution of Thrombospondin-1 and -2 to Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.	THBS1 THBS2	3.44e-06	2	65	2	33981184
Pubmed	Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2.	THBS2 NOS3	3.44e-06	2	65	2	21949402
Pubmed	Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke.	THBS1 THBS2	3.44e-06	2	65	2	18594557
Pubmed	Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.	NLGN4X NLGN4Y	3.44e-06	2	65	2	22989184
Pubmed	Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis.	THBS1 THBS2	3.44e-06	2	65	2	15037577
Pubmed	TSP1 and TSP2 Have Unique and Overlapping Roles in Protecting against Noise-Induced Auditory Synaptopathy.	THBS1 THBS2	3.44e-06	2	65	2	30928339
Pubmed	Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization.	THBS1 THBS2	3.44e-06	2	65	2	17143334
Pubmed	Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Common Brain Tumors.	THBS1 THBS2	3.44e-06	2	65	2	33759165
Pubmed	Increased sensitivity to kindling in mice lacking TSP1.	THBS1 THBS2	1.03e-05	3	65	2	26241338
Pubmed	Expression and function of thrombospondin-1 in myelinating glial cells of the central nervous system.	THBS1 THBS2	1.03e-05	3	65	2	9373030
Pubmed	Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury.	THBS1 THBS2	1.03e-05	3	65	2	18787106
Pubmed	USP9x-mediated deubiquitination of EFA6 regulates de novo tight junction assembly.	PSD PSD4	1.03e-05	3	65	2	20339350
Pubmed	Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells.	THBS1 THBS2	1.03e-05	3	65	2	18032585
Pubmed	Postsynaptic action potentials are required for nitric-oxide-dependent long-term potentiation in CA1 neurons of adult GluR1 knock-out and wild-type mice.	GRIA1 NOS3	1.03e-05	3	65	2	19109486
Pubmed	Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis.	THBS1 THBS2	1.03e-05	3	65	2	19818485
Pubmed	GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension.	THBS1 NOS3	1.03e-05	3	65	2	21059996
Pubmed	Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents.	NLGN4X NLGN4Y	1.03e-05	3	65	2	32011705
Pubmed	EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins.	THBS1 THBS2	1.03e-05	3	65	2	17638877
Pubmed	TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro.	THBS1 THBS2	1.03e-05	3	65	2	30939949
Pubmed	Interactions between CD47 and thrombospondin reduce inflammation.	THBS1 THBS2	1.03e-05	3	65	2	17442977
Pubmed	Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.	THBS1 THBS2	1.03e-05	3	65	2	19004835
Pubmed	Thrombospondin is a tight-binding competitive inhibitor of neutrophil elastase.	THBS1 THBS2	1.03e-05	3	65	2	8463250
Pubmed	Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction.	THBS1 THBS2	1.03e-05	3	65	2	12482844
Pubmed	Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration.	THBS1 NOS3	1.03e-05	3	65	2	16311602
Pubmed	Thrombospondin-1, -2 and -5 have differential effects on vascular smooth muscle cell physiology.	THBS1 THBS2	1.03e-05	3	65	2	26168731
Pubmed	Reduced expression of thrombospondins and craniofacial dysmorphism in mice overexpressing Fra1.	THBS1 THBS2	1.03e-05	3	65	2	16598380
Pubmed	Analysis of the neuroligin 4Y gene in patients with autism.	NLGN4X NLGN4Y	1.03e-05	3	65	2	18628683
Pubmed	Differential Expression Pattern of THBS1 and THBS2 in Lung Cancer: Clinical Outcome and a Systematic-Analysis of Microarray Databases.	THBS1 THBS2	1.03e-05	3	65	2	27513329
Pubmed	Regulation of VEGF-A, VEGFR-I, thrombospondin-1, -2, and -3 expression in a human pituitary cell line (HP75) by TGFbeta1, bFGF, and EGF.	THBS1 THBS2	1.03e-05	3	65	2	15347840
Pubmed	Association between single nucleotide polymorphisms in thrombospondins genes and coronary artery disease: A meta-analysis.	THBS1 THBS2	1.03e-05	3	65	2	25976449
Pubmed	The Pathological Significance and Prognostic Roles of Thrombospondin-1, and -2, and 4N1K-peptide in Bladder Cancer.	THBS1 THBS2	1.03e-05	3	65	2	31092423
Pubmed	mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.	THBS1 THBS2	1.03e-05	3	65	2	34669362
Pubmed	Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers.	THBS1 THBS2	1.03e-05	3	65	2	1459996
Pubmed	Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina.	NLGN4X NLGN4Y	1.03e-05	3	65	2	21282647
Pubmed	Polymorphisms in thrombospondin genes and myocardial infarction: a case-control study and a meta-analysis of available evidence.	THBS1 THBS2	1.03e-05	3	65	2	18178577
Pubmed	Differential expression of thrombospondin 1, 2, and 3 during murine development.	THBS1 THBS2	1.03e-05	3	65	2	8400410
Pubmed	Cocaine Triggers Astrocyte-Mediated Synaptogenesis.	THBS1 THBS2	1.03e-05	3	65	2	33069367
Pubmed	Nucleoside transporters are widely expressed in ovarian carcinoma effusions.	SLC29A1 SLC29A4	2.06e-05	4	65	2	21822668
Pubmed	Thrombospondin 2 potentiates notch3/jagged1 signaling.	THBS1 THBS2	2.06e-05	4	65	2	19147503
Pubmed	Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.	NLGN4X NLGN4Y	2.06e-05	4	65	2	12669065
Pubmed	Homodimerization and isoform-specific heterodimerization of neuroligins.	NLGN4X NLGN4Y	2.06e-05	4	65	2	22671294
Pubmed	Ultrasonic vocalizations in mouse models for speech and socio-cognitive disorders: insights into the evolution of vocal communication.	NLGN4X NLGN4Y	2.06e-05	4	65	2	20579107
Pubmed	The mouse and human genes encoding the recognition component of the N-end rule pathway.	THBS1 EPB42	2.06e-05	4	65	2	9653112
Pubmed	Analysis of four neuroligin genes as candidates for autism.	NLGN4X NLGN4Y	2.06e-05	4	65	2	16077734
Pubmed	Molecular evolution of the equilibrative nucleoside transporter family: identification of novel family members in prokaryotes and eukaryotes.	SLC29A1 SLC29A4	2.06e-05	4	65	2	12446811
Pubmed	Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.	THBS1 THBS2	2.06e-05	4	65	2	6338048
Pubmed	Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations.	NLGN4X NLGN4Y	2.06e-05	4	65	2	17292328
Pubmed	Thrombospondin-1 and thrombospondin-2 mRNA and TSP-1 and TSP-2 protein expression in uterine fibroids and correlation to the genes COL1A1 and COL3A1 and to the collagen cross-link hydroxyproline.	THBS1 THBS2	2.06e-05	4	65	2	18089612
Pubmed	Recognition of the N-terminal modules of thrombospondin-1 and thrombospondin-2 by alpha6beta1 integrin.	THBS1 THBS2	2.06e-05	4	65	2	12909644
Pubmed	Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior.	THBS1 THBS2	2.06e-05	4	65	2	11980922
Pubmed	Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity.	THBS1 THBS2	2.06e-05	4	65	2	10900205
Pubmed	Spontaneous bacterial keratitis in CD36 knockout mice.	THBS1 THBS2	2.06e-05	4	65	2	20847111
Pubmed	Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.	THBS1 THBS2	3.43e-05	5	65	2	30622267
Pubmed	Assessment of myosin II, Va, VI and VIIa loss of function on endocytosis and endocytic vesicle motility in bone marrow-derived dendritic cells.	MYH10 MYO7A	3.43e-05	5	65	2	17615572
Pubmed	Neuroligins and neurexins link synaptic function to cognitive disease.	NLGN4X NLGN4Y	3.43e-05	5	65	2	18923512
Pubmed	Synapse formation: if it looks like a duck and quacks like a duck ...	NLGN4X NLGN4Y	3.43e-05	5	65	2	10996085
Pubmed	Central corneal thickness does not correlate with TonoLab-measured IOP in several mouse strains with single transgenic mutations of matricellular proteins.	THBS1 THBS2	3.43e-05	5	65	2	23806329
Pubmed	EFA6 activates Arf6 and participates in its targeting to the Flemming body during cytokinesis.	PSD PSD4	3.43e-05	5	65	2	23603394
Pubmed	Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.	NLGN4X NLGN4Y	3.43e-05	5	65	2	37865312
Pubmed	The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?	NLGN4X NLGN4Y	5.13e-05	6	65	2	21838267
Pubmed	Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.	NLGN4X NLGN4Y	5.13e-05	6	65	2	29724786
Pubmed	Expression and localization of somatostatin receptor types 3, 4 and 5 in the wild-type, SSTR1 and SSTR1/SSTR2 knockout mouse cochlea.	MYO7A SSTR3	7.18e-05	7	65	2	25149275
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	SCAPER BAZ1B DGCR8 XPO1 UBE3C RPL13A MPG RPL18A	8.36e-05	759	65	8	35915203
Pubmed	Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.	NLGN4X NLGN4Y	9.56e-05	8	65	2	30871858
Pubmed	Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.	THBS1 THBS2	9.56e-05	8	65	2	24460873
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MYH10 ZBED4 KIF1B MTMR3 UBE3C SIPA1L2	1.14e-04	407	65	6	12693553
Pubmed	Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development.	THBS1 THBS2	1.23e-04	9	65	2	1371115
Pubmed	Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions.	NLGN4X NLGN4Y	1.23e-04	9	65	2	23010509
Pubmed	Microglia ablation alleviates myelin-associated catatonic signs in mice.	NLGN4X NLGN4Y	1.23e-04	9	65	2	29252214
Pubmed	Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.	THBS1 THBS2 MYH10	1.29e-04	52	65	3	30389913
Pubmed	USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses.	MYH10 ERCC4	1.53e-04	10	65	2	25538220
Pubmed	SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.	NLGN4X NLGN4Y	1.87e-04	11	65	2	32973045
Pubmed	Behavioral phenotypes of genetic mouse models of autism.	NLGN4X NLGN4Y	1.87e-04	11	65	2	26403076
Pubmed	Advancing the understanding of autism disease mechanisms through genetics.	NLGN4X NLGN4Y	2.65e-04	13	65	2	27050589
Pubmed	Contribution of adenosine related genes to the risk of depression with disturbed sleep.	SLC29A1 SLC29A4	2.65e-04	13	65	2	20392501
Cytoband	7p22.1	RSPH10B2 SLC29A4 RSPH10B	4.20e-05	47	65	3	7p22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr7p22	RSPH10B2 SLC29A4 RSPH10B	9.30e-04	134	65	3	chr7p22
Cytoband	Ensembl 112 genes in cytogenetic band chr7q36	ZNF862 UBE3C NOS3	1.52e-03	159	65	3	chr7q36
ToppCell	facs-Skin-nan-24m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 THBS2 FCGBP GDPD2 RPL13A	5.75e-06	175	65	5	21542be95059983d2c8bdf01ec711fdbf1ec1f62
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 HOXC9 PSD SCAPER NFASC	5.91e-06	176	65	5	b4a23d8d1414434adeb237a96f28c825f1aebd77
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 HOXC9 PSD SCAPER NFASC	5.91e-06	176	65	5	66c9c6b59030f67e8d746a9c6930e50923f2ded1
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP95 MYH10 MYO7A SCUBE3 DGCR8	6.24e-06	178	65	5	6178706db4a855d72abc156537604d575624df56
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP95 MYH10 MYO7A SCUBE3 DGCR8	6.24e-06	178	65	5	f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	THBS1 THBS2 MYH10 GRIA1 NFASC	8.57e-06	190	65	5	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	THBS2 HOXC9 PSD NFASC FAM43B	1.02e-05	197	65	5	31c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS1 THBS2 MYH10 GRIA1 NFASC	1.10e-05	200	65	5	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS1 THBS2 MYH10 GRIA1 NFASC	1.10e-05	200	65	5	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	367C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NLGN4X GRIA1 SLC29A4 PSD4	1.24e-05	97	65	4	a1279377bf0ee5662db8b9303f5f1fd418dee6df
ToppCell	367C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NLGN4X GRIA1 SLC29A4 PSD4	1.24e-05	97	65	4	12cbd03b33e76e5e471bbee2a9c11f27e8b21123
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PSD SCUBE3 ST8SIA5 SLC29A4	9.24e-05	162	65	4	478cf560ef33c5c324142c76417447d4a571a2c9
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	THBS2 HOXC9 FAM43B LDB2	1.02e-04	166	65	4	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	THBS2 HOXC9 FAM43B LDB2	1.02e-04	166	65	4	7c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF1B SCUBE3 NFASC SLC29A4	1.14e-04	171	65	4	dd37e1693a5cfc42e40992d504f92048a8038b52
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR15 JRK SCUBE3 PSD4	1.16e-04	172	65	4	33c201aaa98acbf1901b6fa6ce0d3ff8012a4d94
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	ANKRD42 ZBED4 NOS3 MPG	1.19e-04	173	65	4	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FCGBP KCNJ16 SCUBE3 FER1L5	1.19e-04	173	65	4	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXC9 MYO7A HYAL2 LDB2	1.19e-04	173	65	4	7dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGD NFASC ST8SIA5 SLC29A4	1.24e-04	175	65	4	182e45f5c02214d6b9f317ff5dc43af8b42de978
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KISS1R HYAL2 RSPH10B LDB2	1.27e-04	176	65	4	5d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(INS+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFAP95 KCNJ16 SSTR3 SLC29A1	1.27e-04	176	65	4	6b04672f295d7680ba00714a72785314a619c893
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NLGN4X NOS3 HYAL2 LDB2	1.30e-04	177	65	4	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYH10 GRIA1 HYAL2 LDB2	1.30e-04	177	65	4	b1775e05c28883a15c56628028770bc59d3233fb
ToppCell	Mid-temporal_gyrus_(MTG)\|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GALNTL6 MCHR2 SCAPER GRIA1	1.33e-04	178	65	4	ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCell	-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	MYH10 HOXC9 GRIA1 NFASC	1.36e-04	179	65	4	10fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	GALNTL6 PSD SIPA1L2 LDB2	1.42e-04	181	65	4	7e3bcfa2ba5b98a7df5854aa6e7a31e9a71faa8a
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGD PDZD9 SSTR3 SLC29A4	1.42e-04	181	65	4	2392af8c7f040c23a7d416c2e37419954970c8f4
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PSD NFASC ST8SIA5 SSTR3	1.51e-04	184	65	4	9e5f98f9113e5e38bdadba6d9d2c346177fb35fe
ToppCell	remission-CD8+_T_naive\|remission / disease stage, cell group and cell class	FCGBP PEX12 RPL13A RPL18A	1.51e-04	184	65	4	fe20fa4457d4a4a75689978275b0afb5f6243faf
ToppCell	P28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SLC12A7 NOS3 HYAL2 LDB2	1.51e-04	184	65	4	8ed22b1af04a711203293e7a8b3df6fb9222fad5
ToppCell	remission-CD8+_T_naive\|World / disease stage, cell group and cell class	FCGBP PEX12 RPL13A RPL18A	1.54e-04	185	65	4	69304d7dd406ac7e96d51c239d7035a06d88704f
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HGD NOS3 HYAL2 LDB2	1.57e-04	186	65	4	9c7924875f70420720149287c500b4dfa8d24673
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	THBS1 THBS2 MYH10 NFASC	1.60e-04	187	65	4	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THBS1 THBS2 MYH10 NFASC	1.60e-04	187	65	4	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HGD NOS3 HYAL2 LDB2	1.60e-04	187	65	4	12129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_NK-NK_CD56bright_CD16-\|lymph-node_spleen / Manually curated celltypes from each tissue	P2RY11 HELZ LDB2 MPG	1.60e-04	187	65	4	9000241566f48e435db9409b7255db68b68f6059
ToppCell	facs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 THBS2 FCGBP GDPD2	1.60e-04	187	65	4	9c1013720c248ef201d010806b6e7ad24205e8ee
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HGD NOS3 HYAL2 LDB2	1.60e-04	187	65	4	83930ef55191eff9006113feaeabb3c2fa21fd05
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SIPA1L2 CA5B SLC29A1 NOS3	1.64e-04	188	65	4	524d1d928c9386acf20e53d31894107dd7290dc7
ToppCell	ICU-SEP-Lymphocyte-B-B_memory\|ICU-SEP / Disease, Lineage and Cell Type	KISS1R NLGN4Y RPL13A RPL18A	1.64e-04	188	65	4	b6d81be72bbd72a68722ab51d1a72c436ef9bc17
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SIPA1L2 CA5B SLC29A1 NOS3	1.64e-04	188	65	4	1b57995d70cf81212e8d46dfaf44dbaf9c7bc4d5
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SIPA1L2 CA5B SLC29A1 NOS3	1.64e-04	188	65	4	cd2d1f8e43c252dd8730a5758458ef63e7ffc836
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SIPA1L2 CA5B SLC29A1 NOS3	1.64e-04	188	65	4	f5a2f324f3f6c5078d57130392d3f1ba74f29094
ToppCell	droplet-Lung-nan-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGD NOS3 HYAL2 LDB2	1.64e-04	188	65	4	405efea75233ecf70f7d19b630230798d817b7f2
ToppCell	P28-Endothelial-large_vessel_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SLC12A7 NOS3 HYAL2 RPL18A	1.64e-04	188	65	4	263169029293e005bcffd87db20221fdd2d3917e
ToppCell	5'-Airway_Nasal-Endothelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SIPA1L2 CA5B SLC29A1 NOS3	1.64e-04	188	65	4	6c9d5e4014f807149328ff4eabd5e86dfe18094d
ToppCell	facs-Skin-Telogen-3m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 THBS2 FCGBP GDPD2	1.64e-04	188	65	4	8cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCell	MS-CD4-proli_CD4\|MS / Condition, Cell_class and T cell subcluster	RSPH10B2 RPL13A RPL18A	1.67e-04	73	65	3	b23c66d8028cd122df76311a47b0f2cefc2efcc6
ToppCell	facs-Skin-nan-18m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 THBS2 FCGBP GDPD2	1.67e-04	189	65	4	6c71e81373cb7822de23c193a6350b6df9f567bc
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 FCGBP HOXC9 SLC29A1	1.67e-04	189	65	4	6f0fc5271a7d3682f145e734abc3be6473dda2e2
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NLGN4X NOS3 HYAL2 LDB2	1.67e-04	189	65	4	55a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 FCGBP HOXC9 SLC29A1	1.67e-04	189	65	4	3b9ce8964b16cb2200d30cbb0bfc711dcad2380e
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 FCGBP HOXC9 SLC29A1	1.67e-04	189	65	4	38acb307907fde68b992057714448c1561d69ee3
ToppCell	droplet-Skin-nan-21m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 THBS2 FCGBP SLC29A1	1.71e-04	190	65	4	c1bfc1960a3df49c0f459454a7363804c32418ee
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron\|World / Primary Cells by Cluster	GALNTL6 ST8SIA5 RPL13A RPL18A	1.74e-04	191	65	4	4dd9c8117c4499ed9bde127baf2598603a82080d
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC12A7 NOS3 HYAL2 LDB2	1.74e-04	191	65	4	6e6b2cb390cc5cd0356924a2c36fbe5b5bd5966c
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC12A7 NOS3 HYAL2 LDB2	1.74e-04	191	65	4	482db995930346be69072ace2fd78fd453e97fb5
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS1 NOS3 HYAL2 LDB2	1.78e-04	192	65	4	eafead22bba48ac5ee568faa8946c444445c1034
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	THBS2 MYH10 GRIA1 NFASC	1.81e-04	193	65	4	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	THBS1 THBS2 MYH10 NFASC	1.85e-04	194	65	4	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-proliferating_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FAM43B NOS3 HYAL2 LDB2	1.85e-04	194	65	4	8a4be91414a2e69dd410aa75791f16008204c9a1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 MYH10 NFASC LDB2	1.85e-04	194	65	4	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 MYH10 NFASC LDB2	1.85e-04	194	65	4	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	FCGBP MYO7A RPL13A RPL18A	1.85e-04	194	65	4	58046894446cb250814252a23f60fdd59c114d77
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SIPA1L2 NOS3 HYAL2 LDB2	1.88e-04	195	65	4	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	ASK428-Mesenchymal\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	THBS1 THBS2 MYH10 GRIA1	1.88e-04	195	65	4	2b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCell	(0)_NK_cells-(0)_NK_CD160pos\|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	P2RY11 HELZ LDB2 MPG	1.88e-04	195	65	4	6cbeceb52bb207f3c074e57b5b3f7cfb24fd5877
ToppCell	ASK428-Mesenchymal-Fibroblast\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	THBS1 THBS2 MYH10 GRIA1	1.88e-04	195	65	4	c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-basal_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 GDPD2 RPL13A RPL18A	1.88e-04	195	65	4	eaadc79f53b1cb208c6f7999925f318e1378197f
ToppCell	facs-Skin-nan-18m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXC9 FAM43B RPL13A RPL18A	1.92e-04	196	65	4	81f9754567bbfa67edd304b9ef7b03e7bd9a3b52
ToppCell	10x5'-Liver-Lymphocytic_NK-NK_CD56bright_CD16-\|Liver / Manually curated celltypes from each tissue	P2RY11 HELZ LDB2 MPG	1.92e-04	196	65	4	4ad73515af265432235b698fceb0ba370ced3e52
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	THBS2 MYH10 GRIA1 NFASC	1.92e-04	196	65	4	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	moderate-Lymphoid-NKT\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFAP95 FCGBP RPL13A RPL18A	1.96e-04	197	65	4	003950f6ed32df64014845f9ec56179512a6cecc
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THBS1 THBS2 MYH10 GRIA1	2.00e-04	198	65	4	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	Sepsis-ICU-SEP-Lymphocyte-B-B_memory\|ICU-SEP / Disease, condition lineage and cell class	KISS1R NLGN4Y RPL13A RPL18A	2.00e-04	198	65	4	4ba2eb32889bbf043f4bbb822e08eb45a2b576ef
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	THBS2 MYH10 GRIA1 NFASC	2.00e-04	198	65	4	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	background-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	THBS1 THBS2 NLGN4X NFASC	2.00e-04	198	65	4	79f32f965aed6a10c5cb803173e3db7b32e07a91
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	THBS2 MYH10 GRIA1 NFASC	2.00e-04	198	65	4	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell-(7)_ACKR1+_endothelial_cells\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RPL13A SLC29A1 HYAL2 RPL18A	2.04e-04	199	65	4	6df0e8ec701c763b1cae5cabcc9e3c25cdbfe4bf
ToppCell	18-Airway-Mesenchymal-Cartilage\|Airway / Age, Tissue, Lineage and Cell class	THBS1 SCUBE3 RPL13A RPL18A	2.04e-04	199	65	4	f5d0aa4170367c080d3c2f01d9af3529762917fa
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 MYH10 KCNJ16 SCUBE3	2.04e-04	199	65	4	3cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCell	COVID-19-kidney-Fibroblast-1\|kidney / Disease (COVID-19 only), tissue and cell type	THBS1 THBS2 NFASC LDB2	2.04e-04	199	65	4	9503646ff1ad248181146ce767e9d12e882ec3bd
ToppCell	Sepsis-Bac-SEP-Lymphocyte-T/NK-Treg\|Bac-SEP / Disease, condition lineage and cell class	PEX12 RPL13A NOS3 RPL18A	2.04e-04	199	65	4	e0b6136e28b813299b7ffbe37f1cf830e60cd7d8
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NLGN4X NOS3 HYAL2 LDB2	2.08e-04	200	65	4	ac6b8bc9998d303f788511b8f111e682ea9f3df8
ToppCell	COVID-19-Fibroblasts-Pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	THBS1 THBS2 RPL13A RPL18A	2.08e-04	200	65	4	73e01b7bc43320a991c67a4fd0c04708f893c7ea
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS2 MYH10 GRIA1 NFASC	2.08e-04	200	65	4	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS1 MYH10 GRIA1 NFASC	2.08e-04	200	65	4	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SIPA1L2 NOS3 HYAL2 LDB2	2.08e-04	200	65	4	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS1 THBS2 MYH10 GRIA1	2.08e-04	200	65	4	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS1 MYH10 GRIA1 NFASC	2.08e-04	200	65	4	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	facs-Skin-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM43B RPL13A RPL18A	3.19e-04	91	65	3	48a2c7c4ce9d23762b314e7d2537b3bb38ce6c8e
ToppCell	LA-12._Cytoplasmic_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	FAM43B RPL13A PSD4	4.09e-04	99	65	3	aed68765f60e54b7e2406c5f09fa744fcd844354
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_and_Papillary_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	CFAP95 MYO7A GRIA1	4.86e-04	105	65	3	cfd271e2cd004d6815bcc3ce7cad86fe62b5299b
ToppCell	mild_COVID-19-RBC\|World / disease group, cell group and cell class (v2)	GALNTL6 MYH10 EPB42	6.66e-04	117	65	3	85210be67ddc31903764b7fa6d7029d9656753d3
ToppCell	mild_COVID-19-RBC\|mild_COVID-19 / disease group, cell group and cell class (v2)	GALNTL6 MYH10 EPB42	7.16e-04	120	65	3	cccea760901558ec18d5cbb71c7971c5a51da571
ToppCell	control-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RPL13A EPB42 RPL18A	8.06e-04	125	65	3	30f593fadbe850cedd622711005f9069ad57cc03
ToppCell	LA-10._Endothelium_II\|World / Chamber and Cluster_Paper	ZDHHC16 GRIA1 LDB2	8.64e-04	128	65	3	071becbe97598c2b65580b0989eb664d6fd6c85a
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Rectal_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	GALNTL6 CFAP95 FCGBP	1.07e-03	138	65	3	e1e936ff4080bda2810c5fd1154a706359f377a5
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac1_Htr1d\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	THBS2 GRIA1 SLC29A1	1.10e-03	139	65	3	fe1657ef9aeda7c530dc7febcd3dcd0e1d5f8a48
Drug	BDCRB	SLC29A1 SLC29A4 MPG	3.60e-06	11	65	3	CID000465094
Disease	Diabetic Angiopathies	THBS1 THBS2 NOS3	4.39e-06	16	60	3	C0011875
Disease	Microangiopathy, Diabetic	THBS1 THBS2 NOS3	4.39e-06	16	60	3	C0025945
Disease	uridine measurement	ERCC4 FAM43B	1.94e-03	32	60	2	EFO_0010546

Protein segments in the cluster

Peptide	Gene	Start	Entry
ESHAWRQRLPRKYLS	C2orf16	876	Q68DN1
IHRERSYRFRSVWPE	EPB42	631	P16452
YKTRNRALHPLWESV	CA5B	41	Q9Y2D0
VIFKLPSNRSWHRGY	ABCA12	956	Q86UK0
ILHKIVKYRFSWPFR	BAZ1B	1351	Q9UIG0
RYLAIVWPVVSRKFR	GPR15	131	P49685
HRESRVVTWSRPYFL	DGCR8	321	Q8WYQ5
VTDKREWRPVHYAAF	ANKRD42	126	Q8N9B4
HFPRTVRWFHRLRSI	QPCTL	281	Q9NXS2
VLVYSWHRDREAFPK	CFAP95	46	Q5VTT2
KYASRVFHRVRWAPE	CYP27B1	6	O15528
HTWFLKRIRSSQYPL	RSPH10B	266	P0C881
HTWFLKRIRSSQYPL	RSPH10B2	266	B2RC85
WIHARSTRKKRCPYT	HOXC9	186	P31274
YRFSIRKQRPWHPAV	P2RY11	51	Q96G91
LRYVKAVRPRHLWGF	HYAL2	191	Q12891
SNWAKHFVVVRRPYV	KIF1B	1716	O60333
PRVFAWVYRHQARHK	FAM43B	156	Q6ZT52
KTWHFTIRQYRELVP	LDB2	156	O43679
NAVPSHVFRRAWRKL	JRK	371	O75564
ARRPISISRDWHGYK	PDZD9	176	Q8IXQ8
WYVTVFPLRALHRRT	KISS1R	141	Q969F8
LAWPVADTFYRIHRR	GDPD2	171	Q9HCC8
RVYFRNRWVKTVHPV	HELZ	726	P42694
RDIFSPKRSWKRQRY	NOS3	721	P29474
VQPFRLTRWRTRYKT	MCHR2	136	Q969V1
RHTISVRVKAAPYWL	NFASC	326	O94856
PRVRDHYRATKVAFW	NLGN4Y	576	Q8NFZ3
WQLTLHSRPNYTRKR	CBY2	21	Q8NA61
IYNHSLTLSARWPRK	FCGBP	2136	Q9Y6R7
HAGEWARKPLRFYVR	MPG	266	P29372
KFWGRLERYLPTHSI	ENGASE	381	Q8NFI3
RDHTRVDWKRPKYTS	GRIA1	276	P42261
TYFHRKHWVRIRPLR	CA5BP1	106	Q8WTZ4
LLRTPNWRPRFKFYH	SLC12A7	601	Q9Y666
YERPIAFTARSRKLW	SCUBE3	881	Q8IX30
RHPRKIDLRARYWAF	SCAPER	91	Q9BY12
PRVRDHYRATKVAFW	NLGN4X	576	Q8N0W4
KATYERLFRWLVHRI	MYH10	426	P35580
SFRSWKRIPAVIYRH	MTMR3	211	Q13615
NKRSWLYRILPSVSH	HGD	56	Q93099
LWGYRKDRTLFHPVS	GALNTL6	541	Q49A17
SKRPHVFYLRTADWR	PSD	831	A5PKW4
RYLAVVHPTRSARWR	SSTR3	141	P32745
WSPVEKTYHSCRRRR	FER1L5	931	A0AVI2
KPHVFQLRTADWRLY	PSD4	856	Q8NDX1
YKTPFRRNTTWHRVP	SIPA1L2	1056	Q9P2F8
RFHKLEKWRRPFYRV	ST8SIA5	221	O15466
HPPSSRWKRFYRAFL	PEX12	146	O00623
RIFAPNHVVAKSRFW	RPL18A	31	Q02543
KPRRYLTVVFEHDAW	SLC29A1	381	Q99808
YPRFLRAHWKFLKTV	XPO1	551	O14980
TAYRWRLSHRPKTGF	THBS1	1106	P07996
AYRHLEWPRKTQVSL	nan	401	Q6ZTK2
LFSFTVKWLRRSRHI	TVP23C	146	Q96ET8
YHFRAPSRIFWRTVR	RPL13A	71	P40429
RSSYVPREILWGHRF	KCNJ16	296	Q9NPI9
ILRTYSVPRLCWHFF	ZDHHC16	106	Q969W1
IKRTYRPRSIQRSWF	ZNF862	456	O60290
KVFRYRSGLARHWSI	ZNF841	656	Q6ZN19
WPTFRALLLHRYVVA	SLC29A4	336	Q7RTT9
FVRKLYLWPRFHVAV	ERCC4	186	Q92889
RWHLTHRPKTGYIRV	THBS2	1111	P35442
QLYVPASRHVWRFRR	UBE3C	641	Q15386
RRSAVWKHFYLSPLD	ZBED4	286	O75132
AYLVRKAFRHRLWAV	MYO7A	826	Q13402
RWIIEKYRLSHSSVP	MYSM1	746	Q5VVJ2