Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

4.71e-0651573GO:0030156
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RANBP2 RAPGEF6 RGPD8 ARHGAP23 ARHGAP36 SLC38A9 RGPD1 ARHGAP39 EIF2B5 KNDC1 TNK2 FGD5 SIPA1L2 RASAL1 RGPD5

1.17e-0550715715GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RANBP2 RAPGEF6 RGPD8 ARHGAP23 ARHGAP36 SLC38A9 RGPD1 ARHGAP39 EIF2B5 KNDC1 TNK2 FGD5 SIPA1L2 RASAL1 RGPD5

1.17e-0550715715GO:0030695
GeneOntologyMolecularFunctionprotein kinase activity

NEK10 INSR RIPK4 ULK3 JAK2 IKBKE MTOR MAP4K5 EPHA2 PAK2 MAST1 ULK4 TNK2 PRKG2 PLK4

8.06e-0560015715GO:0004672
GeneOntologyMolecularFunctionkinase activity

NEK10 INSR RIPK4 ULK3 JAK2 IKBKE MTOR MAP4K5 EPHA2 PI4KB PAK2 MAST1 ULK4 TNK2 CARD11 PRKG2 PLK4

1.11e-0476415717GO:0016301
GeneOntologyMolecularFunctionenzyme regulator activity

RANBP2 GBP6 RAPGEF6 RGPD8 ARHGAP23 ARHGAP36 SLC38A9 TPRN RGPD1 ARHGAP39 PPARD NLRC4 TEFM RING1 PARP6 EIF2B5 KNDC1 PAK2 TNK2 FGD5 SIPA1L2 GMPPA RASAL1 PPP1R12C RGPD5

1.16e-04141815725GO:0030234
GeneOntologyMolecularFunctionprotein serine kinase activity

NEK10 RIPK4 ULK3 MTOR MAP4K5 PAK2 MAST1 ULK4 TNK2 PRKG2 PLK4

1.45e-0436315711GO:0106310
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

NEK10 INSR RIPK4 ULK3 JAK2 IKBKE MTOR MAP4K5 EPHA2 PI4KB PAK2 MAST1 ULK4 TNK2 PRKG2 PLK4

1.52e-0470915716GO:0016773
GeneOntologyMolecularFunctionenzyme activator activity

RANBP2 RGPD8 ARHGAP23 ARHGAP36 RGPD1 ARHGAP39 PPARD NLRC4 TEFM RING1 PARP6 PAK2 SIPA1L2 RASAL1 RGPD5

2.14e-0465615715GO:0008047
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

NEK10 RIPK4 ULK3 IKBKE MTOR MAP4K5 PAK2 MAST1 ULK4 TNK2 PRKG2 PLK4

2.19e-0444615712GO:0004674
GeneOntologyMolecularFunctionGTPase activator activity

RANBP2 RGPD8 ARHGAP23 ARHGAP36 RGPD1 ARHGAP39 SIPA1L2 RASAL1 RGPD5

3.73e-042791579GO:0005096
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

NEK10 INSR RIPK4 ULK3 PARP6 JAK2 IKBKE MTOR MAP4K5 EPHA2 PI4KB PAK2 MAST1 ULK4 TNK2 CARD11 PRKG2 PLK4

4.27e-0493815718GO:0016772
GeneOntologyMolecularFunctionSUMO ligase activity

RANBP2 RGPD8 RGPD1

4.93e-04201573GO:0061665
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RANBP2 RGPD8 RGPD1 RGPD5

1.39e-05201564GO:0006607
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RANBP2 RGPD8 RGPD1

2.40e-0581603GO:1990723
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RANBP2 RGPD8 RGPD1

5.08e-05101603GO:0044614
GeneOntologyCellularComponentannulate lamellae

RANBP2 RGPD8 RGPD1

1.51e-04141603GO:0005642
GeneOntologyCellularComponentnuclear pore nuclear basket

RANBP2 RGPD8 RGPD1

3.30e-04181603GO:0044615
GeneOntologyCellularComponentnuclear inclusion body

RANBP2 RGPD8 RGPD1

4.56e-04201603GO:0042405
GeneOntologyCellularComponentSUMO ligase complex

RANBP2 RGPD8 RGPD1

5.29e-04211603GO:0106068
GeneOntologyCellularComponentdendrite

MAP1A IFT57 ACAD9 ERO1A PCLO INSR SYAP1 GPR179 PGR MTOR BRINP2 KNDC1 MAST1 TNK2 IGSF9B KIF17

9.23e-0485816016GO:0030425
GeneOntologyCellularComponentdendritic tree

MAP1A IFT57 ACAD9 ERO1A PCLO INSR SYAP1 GPR179 PGR MTOR BRINP2 KNDC1 MAST1 TNK2 IGSF9B KIF17

9.46e-0486016016GO:0097447
GeneOntologyCellularComponentsex chromatin

RING1 RNF2

1.19e-0371602GO:0001739
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C RIMBP3B

1.25e-03281603GO:0002177
GeneOntologyCellularComponentnuclear envelope

RANBP2 RGPD8 INSR RGPD1 SMPD4 PARP6 TNRC18 MTOR EPC1 NAV3 PRKG2 RGPD5

1.29e-0356016012GO:0005635
GeneOntologyCellularComponentorganelle envelope

RANBP2 RGPD8 ACAD9 INSR RGPD1 SMPD4 TST CPT2 DARS2 PGR PARP6 TNRC18 SLC44A1 IKBKE MTOR PI4KB EPC1 NAV3 PISD PRKG2 TAFAZZIN RGPD5

1.41e-03143516022GO:0031967
GeneOntologyCellularComponentcilium

MAP1A IFT57 PRAMEF22 PDZD7 CEP170 SPTBN5 ULK3 PROM1 PPP3CC CFAP77 ULK4 CEP126 DNAH6 KIF17 DNAH8 TEDC1

1.48e-0389816016GO:0005929
GeneOntologyCellularComponentcaveola

INSR JAK2 SCN5A CTNNA1 CDH13

1.65e-031111605GO:0005901
DomainKinase-like_dom

NEK10 INSR RIPK4 ULK3 JAK2 IKBKE MTOR MAP4K5 EPHA2 PI4KB KNDC1 PAK2 MAST1 ULK4 TNK2 PRKG2 DNM1 PLK4

5.49e-0754215418IPR011009
DomainRan_BP1

RANBP2 RGPD8 RGPD1 RGPD5

2.09e-06121544PF00638
DomainRANBD1

RANBP2 RGPD8 RGPD1 RGPD5

2.09e-06121544PS50196
DomainPH_dom-like

RANBP2 RGPD8 ARHGAP23 RGPD1 SH2B2 SH2B1 SPTBN5 JAK2 MTMR4 FGD5 FRMPD3 DNM1 EPB41L1 RASAL1 RGPD5

2.51e-0642615415IPR011993
DomainRanBD

RANBP2 RGPD8 RGPD1 RGPD5

3.00e-06131544SM00160
DomainRan_bind_dom

RANBP2 RGPD8 RGPD1 RGPD5

3.00e-06131544IPR000156
DomainPDZ

RAPGEF6 ARHGAP23 PCLO PDZD7 MAST1 CARD11 FRMPD3 SIPA1L2 TJP3

4.54e-061511549PS50106
DomainPDZ

RAPGEF6 ARHGAP23 PCLO PDZD7 MAST1 CARD11 FRMPD3 SIPA1L2 TJP3

4.79e-061521549IPR001478
DomainPROTEIN_KINASE_ATP

NEK10 INSR RIPK4 ULK3 JAK2 IKBKE MAP4K5 EPHA2 PAK2 MAST1 ULK4 TNK2 PRKG2 PLK4

2.76e-0545915414PS00107
DomainPDZ

RAPGEF6 ARHGAP23 PDZD7 MAST1 CARD11 FRMPD3 SIPA1L2 TJP3

3.16e-051481548SM00228
Domain-

RAPGEF6 ARHGAP23 PDZD7 MAST1 CARD11 FRMPD3 SIPA1L2 TJP3

3.48e-0515015482.30.42.10
DomainFN3

MYOM1 INSR CMYA5 RIMBP3 PTPRD EPHA2 RIMBP3C IGSF9B RIMBP3B

4.13e-051991549PS50853
DomainProt_kinase_dom

NEK10 INSR RIPK4 ULK3 JAK2 IKBKE MAP4K5 EPHA2 PAK2 MAST1 ULK4 TNK2 PRKG2 PLK4

5.48e-0548915414IPR000719
DomainPROTEIN_KINASE_DOM

NEK10 INSR RIPK4 ULK3 JAK2 IKBKE MAP4K5 EPHA2 PAK2 MAST1 ULK4 TNK2 PRKG2 PLK4

5.98e-0549315414PS50011
DomainFN3_dom

MYOM1 INSR CMYA5 RIMBP3 PTPRD EPHA2 RIMBP3C IGSF9B RIMBP3B

6.05e-052091549IPR003961
DomainGrip

RGPD8 RGPD1 RGPD5

8.64e-05111543SM00755
DomainGRIP

RGPD8 RGPD1 RGPD5

8.64e-05111543PF01465
Domain-

RANBP2 RGPD8 ARHGAP23 RGPD1 SH2B2 SH2B1 SPTBN5 MTMR4 FGD5 DNM1 EPB41L1 RASAL1

9.92e-05391154122.30.29.30
DomainGRIP_dom

RGPD8 RGPD1 RGPD5

1.15e-04121543IPR000237
DomainGRIP

RGPD8 RGPD1 RGPD5

1.15e-04121543PS50913
DomainFN3

MYOM1 INSR CMYA5 PTPRD EPHA2 RIMBP3C IGSF9B RIMBP3B

1.52e-041851548SM00060
DomainPROTEIN_KINASE_TYR

NEK10 INSR JAK2 EPHA2 TNK2 PLK4

1.52e-04971546PS00109
DomainTyr_kinase_AS

NEK10 INSR JAK2 EPHA2 TNK2 PLK4

1.52e-04971546IPR008266
DomainPDZ

RAPGEF6 ARHGAP23 PDZD7 MAST1 FRMPD3 SIPA1L2 TJP3

1.70e-041411547PF00595
DomainPhe_ZIP

SH2B2 SH2B1

2.02e-0431542PF08916
DomainPhe_ZIP

SH2B2 SH2B1

2.02e-0431542IPR015012
DomainSH2B

SH2B2 SH2B1

2.02e-0431542IPR030523
DomainProtein_kinase_ATP_BS

NEK10 INSR ULK3 JAK2 IKBKE MAP4K5 EPHA2 PAK2 TNK2 PRKG2 PLK4

3.14e-0437915411IPR017441
DomainHexapep

EIF2B5 GMPPA

6.65e-0451542IPR001451
DomainHexapep

EIF2B5 GMPPA

6.65e-0451542PF00132
DomainPkinase

NEK10 RIPK4 ULK3 IKBKE MAP4K5 PAK2 MAST1 ULK4 PRKG2 PLK4

1.26e-0338115410PF00069
DomainRab_bind

RGPD8 RGPD1

1.38e-0371542PF16704
DomainGCC2_Rab_bind

RGPD8 RGPD1

1.38e-0371542IPR032023
DomainRAWUL

RING1 RNF2

1.38e-0371542IPR032443
DomainRAWUL

RING1 RNF2

1.38e-0371542PF16207
DomainCARD

CRADD NLRC4 CARD11

1.55e-03281543PF00619
DomainFYVE

MTMR4 ZFYVE26 FGD5

1.72e-03291543PF01363
DomainFYVE

MTMR4 ZFYVE26 FGD5

1.72e-03291543SM00064
Domain-

ATP13A1 ATP10A NT5M NT5DC2

1.92e-036415443.40.50.1000
DomainCARD

CRADD NLRC4 CARD11

2.09e-03311543IPR001315
Domainfn3

MYOM1 INSR CMYA5 PTPRD EPHA2 IGSF9B

2.27e-031621546PF00041
DomainCARD

CRADD NLRC4 CARD11

2.50e-03331543PS50209
DomainZnf_FYVE-rel

MTMR4 ZFYVE26 FGD5

2.73e-03341543IPR017455
Domain-

RGPD8 RGPD1

2.91e-031015421.10.220.60
DomainPROTEIN_KINASE_ST

RIPK4 ULK3 IKBKE MAP4K5 PAK2 MAST1 ULK4 PRKG2 PLK4

3.16e-033621549PS00108
DomainCadherin_tail

PCDHA9 PCDHA7 PCDHA2

3.48e-03371543PF15974
DomainCadherin_CBD

PCDHA9 PCDHA7 PCDHA2

3.48e-03371543IPR031904
DomainZnf_FYVE

MTMR4 ZFYVE26 FGD5

3.75e-03381543IPR000306
DomainSH3_9

RIMBP3 TNK2 RIMBP3C RIMBP3B

3.95e-03781544PF14604
DomainHAD-like_dom

ATP13A1 ATP10A NT5M NT5DC2

4.14e-03791544IPR023214
DomainSulfotransfer_2

CHST12 HS6ST3

4.22e-03121542PF03567
DomainSulfotransferase

CHST12 HS6ST3

4.22e-03121542IPR005331
DomainPkinase_Tyr

INSR JAK2 EPHA2 TNK2 PLK4

4.33e-031291545PF07714
DomainZF_FYVE

MTMR4 ZFYVE26 FGD5

4.34e-03401543PS50178
DomainSH3_2

RIMBP3 RIMBP3C RIMBP3B TJP3

5.59e-03861544PF07653
DomainSH3_2

RIMBP3 RIMBP3C RIMBP3B TJP3

5.59e-03861544IPR011511
DomainSer-Thr/Tyr_kinase_cat_dom

INSR JAK2 EPHA2 TNK2 PLK4

5.75e-031381545IPR001245
DomainDynein_heavy_chain_D4_dom

DNAH6 DNAH8

5.76e-03141542IPR024317
DomainDynein_HC_stalk

DNAH6 DNAH8

5.76e-03141542IPR024743
DomainDynein_heavy_dom-2

DNAH6 DNAH8

5.76e-03141542IPR013602
DomainDHC_N2

DNAH6 DNAH8

5.76e-03141542PF08393
DomainATPase_dyneun-rel_AAA

DNAH6 DNAH8

5.76e-03141542IPR011704
DomainMT

DNAH6 DNAH8

5.76e-03141542PF12777
DomainAAA_8

DNAH6 DNAH8

5.76e-03141542PF12780
DomainAAA_5

DNAH6 DNAH8

5.76e-03141542PF07728
DomainTyr_kinase_cat_dom

INSR JAK2 EPHA2 TNK2

6.06e-03881544IPR020635
DomainRho_GTPase_activation_prot

ARHGAP23 ARHGAP36 ARHGAP39 RASAL1

6.06e-03881544IPR008936
DomainTyrKc

INSR JAK2 EPHA2 TNK2

6.06e-03881544SM00219
DomainTPR_1

RANBP2 RGPD8 RGPD1 RGPD5

6.56e-03901544IPR001440
DomainTPR_1

RANBP2 RGPD8 RGPD1 RGPD5

6.56e-03901544PF00515
DomainDHC_fam

DNAH6 DNAH8

6.61e-03151542IPR026983
DomainDynein_heavy

DNAH6 DNAH8

6.61e-03151542PF03028
DomainPI3/4_kinase_CS

MTOR PI4KB

6.61e-03151542IPR018936
DomainDynein_heavy_dom

DNAH6 DNAH8

6.61e-03151542IPR004273
Domain-

THOC1 CRADD NLRC4 CARD11

7.36e-039315441.10.533.10
DomainZnf_FYVE_PHD

PCLO CXXC1 MTMR4 ZFYVE26 FGD5

7.47e-031471545IPR011011
DomainVWF_type-D

MUC4 MUC6

7.51e-03161542IPR001846
Domain-

MTOR PI4KB

7.51e-031615421.10.1070.11
DomainVWFD

MUC4 MUC6

7.51e-03161542PS51233
DomainPI3Kc

MTOR PI4KB

7.51e-03161542SM00146
DomainVWD

MUC4 MUC6

7.51e-03161542SM00216
DomainVWD

MUC4 MUC6

7.51e-03161542PF00094
DomainFERM_central

JAK2 FRMPD3 EPB41L1

7.68e-03491543IPR019748
DomainFERM_domain

JAK2 FRMPD3 EPB41L1

7.68e-03491543IPR000299
DomainFERM_1

JAK2 FRMPD3 EPB41L1

8.12e-03501543PS00660
DomainFERM_2

JAK2 FRMPD3 EPB41L1

8.12e-03501543PS00661
DomainFERM_3

JAK2 FRMPD3 EPB41L1

8.12e-03501543PS50057
DomainBand_41_domain

JAK2 FRMPD3 EPB41L1

8.12e-03501543IPR019749
DomainB41

JAK2 FRMPD3 EPB41L1

8.12e-03501543SM00295
DomainTPR-contain_dom

RANBP2 RGPD8 RGPD1 EDRF1 RGPD5

8.12e-031501545IPR013026
Pubmed

Kinase activation through dimerization by human SH2-B.

INSR SH2B2 SH2B1 JAK2

2.26e-095162415767667
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

RAPGEF6 ATP13A1 SH2B2 JAK2 SCAF1 TNRC18 ZFP36L2 INF2 KCNG1 MTOR SCN5A ZNF500 PIGW ULK4 TNK2 ZFYVE26 SIPA1L2 RASAL1 RAI1 TJP3

2.44e-0711051622035748872
Pubmed

Lnk inhibits myeloproliferative disorder-associated JAK2 mutant, JAK2V617F.

SH2B2 SH2B1 JAK2

3.95e-074162319293402
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

3.95e-074162319091768
Pubmed

Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.

RANBP2 RGPD8 RGPD5

3.95e-07416239480752
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

9.85e-075162317855024
Pubmed

Regulation of insulin and type 1 insulin-like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteins.

INSR SH2B2 SH2B1

1.96e-066162323190452
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

RANBP2 ACAD9 ERO1A APRT MTMR4 PTPRD WDR97 MTOR NT5DC2 EPHA2 AGL BOP1 CTNNA1 PRORP SIPA1L2 HSP90AA4P HSP90AB3P

3.36e-069741621728675297
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RANBP2 RGPD8 RGPD1

3.42e-06716239037092
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD8 RGPD1 RGPD5

3.42e-067162315710750
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RANBP2 RGPD8 RGPD1

3.42e-067162311353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RANBP2 RGPD8 RGPD1

3.42e-067162330944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RANBP2 RGPD8 RGPD1

3.42e-067162338838144
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RANBP2 RGPD8 RGPD1

3.42e-06716237559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RANBP2 RGPD8 RGPD1

3.42e-067162317372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RANBP2 RGPD8 RGPD1

3.42e-067162338657106
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RANBP2 RGPD8 RGPD1

3.42e-067162321205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RANBP2 RGPD8 RGPD1

3.42e-067162318949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RANBP2 RGPD8 RGPD1

3.42e-067162325187515
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RANBP2 RGPD8 RGPD1

3.42e-06716238603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RANBP2 RGPD8 RGPD1

3.42e-067162326632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RANBP2 RGPD8 RGPD1

3.42e-067162324403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RANBP2 RGPD8 RGPD1

3.42e-067162323818861
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RANBP2 RGPD8 RGPD1

3.42e-067162323536549
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RANBP2 RGPD8 RGPD1

3.42e-067162312191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RANBP2 RGPD8 RGPD1

3.42e-067162322821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RANBP2 RGPD8 RGPD1

3.42e-067162320682751
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RANBP2 RGPD8 RGPD1

5.46e-068162321670213
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RANBP2 RGPD8 RGPD1

5.46e-068162327412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RANBP2 RGPD8 RGPD1

5.46e-068162321310149
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RANBP2 RGPD8 RGPD1

5.46e-068162322262462
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RANBP2 RGPD8 RGPD1

5.46e-068162328745977
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

GBP6 ARHGAP23 INSR DARS2 RING1 CEP170 ULK3 JAK2 RNF2 IKBKE MAP4K5 EPHA2 TNK2 BOP1 IGSF9B PLK4

6.04e-069101621636736316
Pubmed

The DNA sequence and biological annotation of human chromosome 1.

EPHX1 PADI4 PRAMEF22 CPT2 RUNX3 PPCS DARS2 CEP170 VPS13D RNF2 PER3 IKBKE MTOR PI4KB BRINP2 SIPA1L2 KIF17

7.09e-0610311621716710414
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RANBP2 RGPD8 RGPD1

8.16e-069162318394993
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RANBP2 RGPD8 RGPD1

8.16e-069162328100513
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RANBP2 RGPD8 RGPD1

8.16e-069162317887960
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RANBP2 RGPD8 RGPD1

8.16e-069162311553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RANBP2 RGPD8 RGPD1

8.16e-069162310601307
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RANBP2 RGPD8 RGPD1

8.16e-06916239733766
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RANBP2 RGPD8 RGPD1

8.16e-069162328877029
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RANBP2 RGPD8 RGPD1

1.16e-0510162327160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RANBP2 RGPD8 RGPD1

1.16e-0510162316332688
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RANBP2 RGPD8 RGPD1

1.16e-051016238857542
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RANBP2 RGPD8 RGPD1

1.16e-0510162321859863
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RANBP2 RGPD8 RGPD1

1.59e-0511162317069463
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RANBP2 RGPD8 RGPD1

1.59e-0511162335771867
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RANBP2 RGPD8 RGPD1

1.59e-0511162334110283
Pubmed

DHHC protein family targets different subsets of glioma stem cells in specific niches.

INSR RING1 RNF2 MTOR

1.67e-0533162430658672
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CYP4V2 CRADD SLC38A9 INSR ARHGAP39 ATP10A SH2B1 CEP170 JAK2 TNRC18 INF2 KNDC1 MAST1 TNK2 PISD IGSF9B PRORP USP3 EPB41L1 RAI1

2.16e-0514891622028611215
Pubmed

Whole Exome Sequencing in Eight Thai Patients With Leber Congenital Amaurosis Reveals Mutations in the CTNNA1 and CYP4V2 Genes.

CYP4V2 CTNNA1

2.16e-052162228453600
Pubmed

USP3 promotes osteosarcoma progression via deubiquitinating EPHA2 and activating the PI3K/AKT signaling pathway.

EPHA2 USP3

2.16e-052162238531846
Pubmed

APS-mediated ubiquitination of the insulin receptor enhances its internalization, but does not induce its degradation.

INSR SH2B2

2.16e-052162217102568
Pubmed

Polycomb directs timely activation of germline genes in spermatogenesis.

RING1 RNF2

2.16e-052162228924034
Pubmed

Elevated glucose represses lysosomal and mTOR-related genes in renal epithelial cells composed of progenitor CD133+ cells.

PROM1 MTOR

2.16e-052162233764985
Pubmed

PPARδ induces estrogen receptor-positive mammary neoplasia through an inflammatory and metabolic phenotype linked to mTOR activation.

PPARD MTOR

2.16e-052162223811944
Pubmed

Identification of host variants associated with overall survival of esophageal cancer patients receiving platinum-based therapy.

PPARD SLC22A1

2.16e-052162232285752
Pubmed

Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling.

SH2B1 JAK2

2.16e-05216229343427
Pubmed

Polycomb function during oogenesis is required for mouse embryonic development.

RING1 RNF2

2.16e-052162222499591
Pubmed

METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity.

ADAMTS1 ADAMTS8

2.16e-052162210438512
Pubmed

Associations between INSR and MTOR polymorphisms in type 2 diabetes mellitus and diabetic nephropathy in a Northeast Chinese Han population.

INSR MTOR

2.16e-052162225867326
Pubmed

Differential role of SH2-B and APS in regulating energy and glucose homeostasis.

SH2B2 SH2B1

2.16e-052162216455776
Pubmed

Citrullinating enzyme PADI4 and transcriptional repressor RING1B bind in cancer cells.

PADI4 RNF2

2.16e-052162238878927
Pubmed

High activity of fatty acid oxidation enzymes in human placenta: implications for fetal-maternal disease.

ACAD9 CPT2

2.16e-052162212971426
Pubmed

Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.

SLC38A9 MTOR

2.16e-052162225963655
Pubmed

Identification of the APS protein as a novel insulin receptor substrate.

INSR SH2B2

2.16e-052162210196204
Pubmed

The role of ADAMTS genes in the end stage of hip osteoarthritis.

ADAMTS1 ADAMTS8

2.16e-052162230655094
Pubmed

EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation.

MTOR EPHA2

2.16e-052162220360610
Pubmed

Structural basis for phosphotyrosine recognition by the Src homology-2 domains of the adapter proteins SH2-B and APS.

SH2B1 JAK2

2.16e-052162216824542
Pubmed

Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease.

MTOR GAA

2.16e-052162220554235
Pubmed

Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells.

RING1 RNF2

2.16e-052162218037880
Pubmed

Gene Body Methylation of the Lymphocyte-Specific Gene CARD11 Results in Its Overexpression and Regulates Cancer mTOR Signaling.

MTOR CARD11

2.16e-052162234348992
Pubmed

Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases.

ADAMTS1 PGR

2.16e-052162210781075
Pubmed

Loss- and gain-of-function mutations show a polycomb group function for Ring1A in mice.

RING1 RNF2

2.16e-052162211060235
Pubmed

Molecular features of 23 patients with glycogen storage disease type III in Turkey: a novel mutation p.R1147G associated with isolated glucosidase deficiency, along with 9 AGL mutations.

AGL GAA

2.16e-052162219834502
Pubmed

CFP1 governs uterine epigenetic landscapes to intervene in progesterone responses for uterine physiology and suppression of endometriosis.

CXXC1 PGR

2.16e-052162237270588
Pubmed

PLK4 is a determinant of temozolomide sensitivity through phosphorylation of IKBKE in glioblastoma.

IKBKE PLK4

2.16e-052162230529153
Pubmed

Pro-Apoptotic Activity of Ruxolitinib Alone and in Combination with Hydroxyurea, Busulphan, and PI3K/mTOR Inhibitors in JAK2-Positive Human Cell Lines.

JAK2 MTOR

2.16e-052162225931349
Pubmed

Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression.

RING1 RNF2

2.16e-052162219412891
Pubmed

Immunohistochemical expression profiles of mucin antigens in salivary gland mucoepidermoid carcinoma: MUC4- and MUC6-negative expression predicts a shortened survival in the early postoperative phase.

MUC4 MUC6

2.16e-052162228649694
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RANBP2 RGPD8 RGPD1

2.74e-0513162331427429
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

3.48e-0514162317662146
Pubmed

Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.

PCDHA9 PCDHA7 PCDHA2

4.33e-0515162315640798
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RANBP2 RGPD8 RGPD1

4.33e-0515162314697343
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RAPGEF6 ITPRID2 CEP170 VPS13D MTMR4 ZFP36L2 IKBKE MTOR PI4KB SIPA1L2 PLK4 EDRF1 EPB41L1 PPP1R12C

5.50e-058611621436931259
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

RAPGEF6 MAP1A RGPD1 SYAP1 VPS13D EPHA2 SIPA1L2

5.94e-05209162736779422
Pubmed

Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.

PCDHA9 PCDHA7 PCDHA2

6.43e-0517162329911975
Pubmed

Periovulatory insulin signaling is essential for ovulation, granulosa cell differentiation, and female fertility.

INSR PGR

6.45e-053162231908002
Pubmed

Secretory carcinoma of breast: pattern of MUC 2/MUC 4/MUC 6 expression.

MUC4 MUC6

6.45e-053162223305535
Pubmed

Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome.

RING1 RNF2

6.45e-053162226323060
Pubmed

Tyrosine 813 is a site of JAK2 autophosphorylation critical for activation of JAK2 by SH2-B beta.

SH2B1 JAK2

6.45e-053162215121872
Pubmed

Targeted inhibition of ACK1 can inhibit the proliferation of hepatocellular carcinoma cells through the PTEN/AKT/mTOR pathway.

MTOR TNK2

6.45e-053162232162707
Pubmed

Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program.

RING1 RNF2

6.45e-053162227913604
Pubmed

Interaction between Calpain 5, Peroxisome proliferator-activated receptor-gamma and Peroxisome proliferator-activated receptor-delta genes: a polygenic approach to obesity.

PPARD CAPN5

6.45e-053162218657264
Pubmed

Heightened uterine mammalian target of rapamycin complex 1 (mTORC1) signaling provokes preterm birth in mice.

PGR MTOR

6.45e-053162222025690
Pubmed

Structural Basis of Diverse Homophilic Recognition by Clustered α- and β-Protocadherins.

PCDHA9 PCDHA7

6.45e-053162227161523
Pubmed

Polycomb potentiates meis2 activation in midbrain by mediating interaction of the promoter with a tissue-specific enhancer.

RING1 RNF2

6.45e-053162224374176
Pubmed

Progesterone acts via the progesterone receptor to induce adamts proteases in ovarian cancer cells.

ADAMTS1 PGR

6.45e-053162226916548
Pubmed

Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation.

RING1 RNF2

6.45e-053162224856970
Pubmed

The nuclear import of ribosomal proteins is regulated by mTOR.

RANBP2 MTOR

6.45e-053162225294810
GeneFamilyPDZ domain containing

RAPGEF6 ARHGAP23 PCLO PDZD7 MAST1 CARD11 FRMPD3 SIPA1L2 TJP3

1.38e-071529891220
GeneFamilyFibronectin type III domain containing

MYOM1 INSR CMYA5 PTPRD EPHA2 IGSF9B

2.35e-04160986555
GeneFamilyWD repeat domain containing|Caspase recruitment domain containing|Apoptosome

CRADD NLRC4 CARD11

5.64e-0430983959
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

MTMR4 ZFYVE26 FGD5

6.22e-043198381
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGAP23 SH2B2 SH2B1 FGD5 DNM1 RASAL1

8.97e-04206986682
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

JAK2 FRMPD3 EPB41L1

2.52e-03509831293
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP23 ARHGAP36 ARHGAP39

2.52e-0350983721
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RANBP2 RGPD8 RGPD1 RGPD5

3.54e-03115984769
GeneFamilyDyneins, axonemal

DNAH6 DNAH8

3.75e-0317982536
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS1 ADAMTS8

4.68e-031998250
GeneFamilyClustered protocadherins

PCDHA9 PCDHA7 PCDHA2

5.07e-036498320
GeneFamilyCD molecules|Mucins

MUC4 MUC6

5.71e-0321982648
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A IFT57 NEK10 PROM1 CEP126 DNAH6 MUC4 PLK4

4.91e-071911618683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

NEK10 BCO2 CFAP77 EPHA2 KNDC1 CAPN5 CEP126 MUC4

5.11e-0719216189cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYOM1 ADAMTS1 LRRTM3 CPED1 GUCY1A2 IGSF9B HS6ST3 CDH13

6.95e-072001618a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellBiopsy_IPF-Epithelial|Biopsy_IPF / Sample group, Lineage and Cell type

EPHX1 IFT57 COLCA1 PROM1 CEP126 DNAH6 MUC4 TJP3

6.95e-07200161876f1ac00b34d07057d8da03d276438b719b46b1d
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS1 LRRTM3 CPED1 PROM1 PTPRD NT5DC2 PRKG2

2.02e-061611617b19f82dd98a3064581793711bb70373f18abecd9
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYOM1 LRRTM3 CMYA5 CPED1 BCO2 SCN5A CDH13

3.65e-0617616179df7a124ebafb0087da0cda133a394275d7bed81
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 LRRTM3 CPED1 ATP10A GUCY1A2 SIPA1L2 HS6ST3

3.79e-0617716174943d040eee0f9dceaddc7498171281d170e271f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 LRRTM3 CPED1 ATP10A GUCY1A2 SIPA1L2 HS6ST3

3.79e-0617716173f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEK10 ARHGAP39 PROM1 WDR97 CEP126 DNAH6 MUC4

3.94e-0617816173b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYOM1 LRRTM3 CMYA5 CPED1 BCO2 SCN5A CDH13

4.39e-061811617719eb532453ab7cd7893726885bc75d74a10b21e
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

MYOM1 LRRTM3 CMYA5 CPED1 BCO2 HS6ST3 CDH13

5.07e-0618516176baccb26f999145e51b91d94315bf8d4655bef31
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

MYOM1 NEK10 LRRTM3 CMYA5 CPED1 BCO2 CDH13

5.64e-0618816170758b474457efa36488e0195f7357100f4b6a090
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MAP1A ACAD9 FAM131A ITPRID2 PARP6 VPS13D EPB41L1

5.64e-061881617b1ec7c45aedcc3d22cac898c6a3679e7f8b44c77
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

MYOM1 CRADD NEK10 LRRTM3 CMYA5 SCN5A CDH13

5.84e-0618916179c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A IFT57 NEK10 PROM1 CEP126 DNAH6 MUC4

5.84e-061891617b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MAP1A NEK10 PROM1 BCO2 CFAP77 CEP126 DNAH6

6.04e-061901617a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCellCiliated_cells-A|World / lung cells shred on cell class, cell subclass, sample id

MAP1A NEK10 PROM1 CFAP77 CEP126 DNAH6 MUC4

6.04e-061901617cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 ADAMTS1 CPED1 ATP10A JAK2 IGSF9B CDH13

6.47e-061921617bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 ADAMTS1 CPED1 ATP10A JAK2 IGSF9B CDH13

6.47e-061921617b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EPHX1 MAP1A NEK10 PROM1 CFAP77 KNDC1 DNAH6

6.47e-06192161703acd4a26b986e34eee608747347791122f1aa52
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EPHX1 MAP1A NEK10 PROM1 CFAP77 KNDC1 DNAH6

6.47e-06192161731c6046589e2fbb0486fd044c5b128099d37872f
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

MYOM1 INSR LRRTM3 CMYA5 CPED1 BCO2 SCN5A

6.69e-061931617dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 CPED1 ATP10A PGR JAK2 GUCY1A2 HS6ST3

7.40e-0619616171522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 CPED1 ATP10A PGR JAK2 GUCY1A2 HS6ST3

7.40e-0619616171c8294014713684b50885e638668f2ce75f357f0
ToppCellControl-Endothelial-Epi-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PADI4 SYAP1 EPHA2 PRKG2 DNAH6 TJP3

2.31e-0515716164d02c50d5d1b892ea241e98724386d8a5a156a46
ToppCellControl-Endothelial-Epi-like-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PADI4 SYAP1 EPHA2 PRKG2 DNAH6 TJP3

2.31e-0515716162c369660c752c0fb3bd798a561d3359e2f9aa983
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

ATP13A1 ITPRID2 INF2 EPHA2 MUC4 TEDC1

2.48e-051591616655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPHX1 INSR PROM1 EPHA2 BRINP2 MUC4

2.66e-0516116162d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellBAL-Mild-cDC_5|Mild / Compartment, Disease Groups and Clusters

PADI4 MAP1A INSR EPHA2 ZNF500 RGPD5

2.66e-0516116167a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ADAMTS1 SLC38A9 PDZD7 ADAMTS8 IGSF9B CDH13

2.86e-0516316161e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Sc17a7.Tshz2-Smoc1_(Agranular_Retrosplenial_cortex_(RSG)_(Smoc1+))-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TDRD9 NEK10 SLC22A1 MUC6

2.95e-054916144845246699a56fea657fd2697b612e93248f590f
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Sc17a7.Tshz2-Smoc1_(Agranular_Retrosplenial_cortex_(RSG)_(Smoc1+))|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TDRD9 NEK10 SLC22A1 MUC6

2.95e-054916145f1c5ebb6f113513b7e6945dfab07c3c34ebab41
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYOM1 LRRTM3 CMYA5 CPED1 BCO2 SCN5A

3.62e-0517016163f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEK10 ARHGAP39 EPHA2 KNDC1 DNAH6 PLK4

3.74e-0517116161854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO SCAF1 MTOR ULK4 IGSF9B MUC4

4.12e-051741616f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-5|TCGA-Pancreas / Sample_Type by Project: Shred V9

ARHGAP23 ERO1A EPHA2 MUC4 CDCA5 PLK4

4.12e-05174161673e1ad4007d94fca25ed7c6fbe5d205d4e1b8a3b
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A NEK10 PROM1 CEP126 DNAH6 MUC4

4.97e-0518016161f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

MYOM1 CRADD LRRTM3 CMYA5 CPED1 BCO2

5.29e-051821616287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPHX1 CRACR2A INSR COLCA1 PROM1 MUC4

5.29e-0518216163f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

PROM1 INF2 CAPN5 SIPA1L2 MUC4 EPB41L1

5.45e-05183161615d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

MYOM1 LRRTM3 CMYA5 CPED1 HS6ST3 CDH13

5.62e-051841616ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellCiliated_cells-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MAP1A PROM1 CFAP77 CEP126 DNAH6 MUC4

5.62e-05184161607c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYOM1 LRRTM3 CMYA5 CPED1 BCO2 SCN5A

5.62e-051841616e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYOM1 LRRTM3 CMYA5 CPED1 SCN5A CDH13

5.79e-051851616549eeb521c3985bff396ea0f202db21822efa51f
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MAP1A NEK10 PROM1 CFAP77 CEP126 DNAH6

5.79e-051851616f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCelldroplet-Marrow-nan-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1A PPM1M APRT PROM1 IKBKE PLK4

5.96e-051861616332931f92352b464c7f23aeebf313cf7db6d499c
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ADAMTS8 ITPRID2 CPED1 PROM1 FGD5 CDH13

5.96e-051861616cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 LRRTM3 CPED1 ATP10A GUCY1A2 HS6ST3

6.14e-05187161648bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

CRADD NEK10 LRRTM3 CMYA5 SCN5A CDH13

6.14e-05187161678cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 LRRTM3 CPED1 ATP10A GUCY1A2 HS6ST3

6.14e-051871616958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 LRRTM3 CPED1 ATP10A GUCY1A2 HS6ST3

6.33e-051881616b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MAP1A NEK10 BCO2 CFAP77 CEP126 DNAH6

6.33e-05188161682c006f43c93f4a867953a446864f02b44536a23
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ACAD9 FAM131A ITPRID2 PARP6 VPS13D EPB41L1

6.33e-0518816162c4e791df69a9df29922f9117e5cac7787c129ce
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MAP1A NEK10 BCO2 CFAP77 CEP126 DNAH6

6.33e-051881616da59b5c0a4b11690a39a964c1a0a83e66aa0972b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 CPED1 ATP10A JAK2 IGSF9B CDH13

6.52e-051891616127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 CPED1 ATP10A JAK2 IGSF9B CDH13

6.52e-0518916162cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

MYOM1 LRRTM3 CMYA5 CPED1 JAK2 CDH13

6.52e-0518916160a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

MYOM1 LRRTM3 CMYA5 CPED1 JAK2 CDH13

6.71e-05190161693c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYOM1 LRRTM3 CMYA5 CPED1 SCN5A CDH13

6.71e-051901616918ad5037881212008f9f69d5df5da91fd01422c
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|343B / Donor, Lineage, Cell class and subclass (all cells)

NEK10 PROM1 CFAP77 CEP126 DNAH6 MUC4

6.71e-051901616169e600e95878000acf5d11f813f9028c7249646
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|343B / Donor, Lineage, Cell class and subclass (all cells)

NEK10 PROM1 CFAP77 CEP126 DNAH6 MUC4

6.71e-0519016160cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCellEpithelial_cells-Ciliated_cells-A|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

MAP1A NEK10 PROM1 CFAP77 CEP126 MUC4

6.71e-051901616549d813a8f23b175875e53347928941f143e236c
ToppCellfacs-Lung-nan-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PNMA1 CFAP77 KNDC1 ULK4 KLHDC7A DNAH6

6.71e-051901616e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

MAP1A NEK10 PROM1 CFAP77 CEP126 DNAH6

6.71e-0519016167031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

MAP1A NEK10 PROM1 CFAP77 CEP126 DNAH6

6.71e-051901616426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellfacs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PNMA1 CFAP77 KNDC1 ULK4 KLHDC7A DNAH6

6.71e-051901616fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

MYOM1 NEK10 LRRTM3 CMYA5 SCN5A CDH13

6.71e-051901616fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEK10 CMYA5 SLC44A1 CARD11 RASAL1 TJP3

6.91e-0519116163e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell356C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MAP1A NEK10 PROM1 CFAP77 CEP126 MUC4

6.91e-051911616dad675251e129254955eac179c84a641a4864586
ToppCell356C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MAP1A NEK10 PROM1 CFAP77 CEP126 MUC4

6.91e-0519116166d2cf41ee946137c039ddcc13593fc3f670afbba
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NEK10 PROM1 CFAP77 CEP126 DNAH6 MUC4

6.91e-051911616e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NEK10 PROM1 CFAP77 CEP126 DNAH6 MUC4

6.91e-0519116169d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NEK10 PROM1 CFAP77 CEP126 DNAH6 MUC4

6.91e-0519116161c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

MYOM1 LRRTM3 CMYA5 CPED1 BCO2 CDH13

7.11e-051921616ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

NEK10 PROM1 CFAP77 CEP126 DNAH6 MUC4

7.11e-051921616eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPHX1 NEK10 COLCA1 BCO2 CEP126 DNAH6

7.31e-051931616ea345d34440b25f65358a53dc72831998d1c3620
ToppCellLAM-Epithelial-AirwayEpi|Epithelial / Condition, Lineage and Cell class

MAP1A NEK10 PROM1 CFAP77 CEP126 MUC4

7.31e-051931616f2672d2c495ee12c3b7d132452bde581fa5a7856
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

GBP6 NEK10 PROM1 KNDC1 DNAH6 MUC4

7.53e-051941616756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEK10 CMYA5 SLC44A1 CARD11 RASAL1 TJP3

7.53e-05194161604bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEK10 CMYA5 SLC44A1 CARD11 RASAL1 TJP3

7.53e-05194161669bff17df4a760ccf081cf52ff04af02c14f448d
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PADI4 TST PGR PROM1 TNK2 CAPN5

7.53e-051941616715e02e5f3250b1bfdc26b7dfd656ba4e705ea84
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 CPED1 ATP10A JAK2 IGSF9B CDH13

7.53e-0519416165c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

MYOM1 LRRTM3 CMYA5 BCO2 SCN5A CDH13

7.53e-051941616c3535f7cc0076653c72db582047cff053c322397
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 CPED1 ATP10A JAK2 IGSF9B CDH13

7.53e-051941616ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEK10 PROM1 ULK4 CEP126 DNAH6 MUC4

7.53e-0519416164a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 CPED1 ATP10A GUCY1A2 HS6ST3 CDH13

7.53e-051941616ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

NEK10 PROM1 CFAP77 CEP126 DNAH6 MUC4

7.53e-05194161643be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

MYOM1 LRRTM3 CMYA5 CPED1 BCO2 SCN5A

7.74e-051951616f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A IFT57 NEK10 PROM1 CEP126 DNAH6

7.74e-051951616649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCellParenchymal-NucSeq-Immune_Myeloid-Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PADI4 PNMA1 MYOM1 MAP1A RHD NT5M

7.74e-051951616027075e9c62b5754a014a9d1393e1b0f5ae42e41
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

MYOM1 INSR LRRTM3 CMYA5 CPED1 SCN5A

7.74e-05195161675fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellParenchymal-NucSeq-Immune_Myeloid-Myeloid-Megakaryocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PADI4 PNMA1 MYOM1 MAP1A RHD NT5M

7.74e-0519516161bcc0c8b1281396b1433ce5a2ec8681de47ce9ad
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEK10 PROM1 BCO2 CEP126 DNAH6 MUC4

7.74e-05195161679dc031258579ea328181dda33710dd897f1064a
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A IFT57 NEK10 PROM1 CEP126 DNAH6

7.74e-051951616129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A IFT57 NEK10 PROM1 CEP126 DNAH6

7.74e-0519516163e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A IFT57 NEK10 PROM1 CEP126 DNAH6

7.74e-0519516166365e3893e38231090ec2dbef010dec71dea3d07
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYOM1 GPRC6A LRRTM3 CPED1 IGSF9B HS6ST3

7.96e-0519616169830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYOM1 CPED1 PGR GUCY1A2 IGSF9B CDH13

8.19e-051971616bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A NEK10 PROM1 CEP126 DNAH6 MUC4

8.19e-05197161691637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A NEK10 PROM1 CEP126 DNAH6 MUC4

8.19e-05197161622c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
DiseaseAcute necrotizing encephalopathy of childhood

RANBP2 CPT2

2.74e-0521552C4706387
DiseaseLuo-Schoch-Yamamoto syndrome (implicated_via_orthology)

RING1 RNF2

2.74e-0521552DOID:0070416 (implicated_via_orthology)
DiseaseSarcomatoid Renal Cell Carcinoma

CRADD APRT MTOR NAV3 CARD11 MUC4

6.10e-051281556C1266043
DiseaseChromophobe Renal Cell Carcinoma

CRADD APRT MTOR NAV3 CARD11 MUC4

6.10e-051281556C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

CRADD APRT MTOR NAV3 CARD11 MUC4

6.10e-051281556C1266044
DiseasePapillary Renal Cell Carcinoma

CRADD APRT MTOR NAV3 CARD11 MUC4

6.10e-051281556C1306837
DiseaseRenal Cell Carcinoma

CRADD APRT MTOR NAV3 CARD11 MUC4

6.10e-051281556C0007134
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

CRADD APRT MTOR NAV3 CARD11 MUC4

1.36e-041481556C0279702
Diseasemonoclonal gammopathy

PTPRD ULK4 HS6ST3 CDH13

1.76e-04531554EFO_0000203
Diseaselung carcinoma (is_marker_for)

JAK2 MUC4

2.71e-0451552DOID:3905 (is_marker_for)
Diseasemucinous adenocarcinoma (is_marker_for)

MUC4 MUC6

2.71e-0451552DOID:3030 (is_marker_for)
Disease4-hydroxychlorothalonil measurement

CXXC1 HSP90AB3P

2.71e-0451552EFO_0800992
Diseaseinflammatory bowel disease (implicated_via_orthology)

RUNX3 ANKZF1 EPB41L1

3.00e-04251553DOID:0050589 (implicated_via_orthology)
Diseaseperipheral neuropathy, response to bortezomib

CMYA5 CDH13

4.06e-0461552EFO_0003100, EFO_0007808
Diseaseneural cell adhesion molecule 1, 120 kda isoform measurement

MAP4K5 NT5DC2

4.06e-0461552EFO_0020593
Diseaseadipoylcarnitine (C6-DC) measurement

CPT2 SLC22A1

4.06e-0461552EFO_0800380
Disease1,5 anhydroglucitol measurement

PCDHA9 PCDHA7 PCDHA2

4.70e-04291553EFO_0008009
DiseaseOvarian Mucinous Adenocarcinoma

NEK10 MTOR TNK2

5.74e-04311553C1335167
DiseaseL-Selectin measurement

NT5M MAP4K5 TENM1

5.74e-04311553EFO_0008202
Diseasegout

PPARD CXXC1 PTPRD MAP4K5 SLC22A1 HSP90AB3P

6.12e-041961556EFO_0004274
Diseasebody surface area

CRADD SLC38A9 INSR RGPD1 CPED1 MTOR MAP4K5 ULK4 PRKG2 HS6ST3 CDH13

6.17e-0464315511EFO_0022196
Diseaseciliopathy (implicated_via_orthology)

IFT57 MAP4K5 PLK4

1.22e-03401553DOID:0060340 (implicated_via_orthology)
Diseaseparental longevity

GBP6 ADAMTS1 ATP13A1 PCLO PTPRD GUCY1A2 SLC22A1 HS6ST3 CDH13

1.25e-034941559EFO_0007796
Diseaseautosomal dominant nonsyndromic deafness (is_implicated_in)

THOC1 PI4KB

1.46e-03111552DOID:0050564 (is_implicated_in)
Diseaseendometrial carcinoma, endometriosis

PGR PTPRD

1.46e-03111552EFO_0001065, EFO_1001512
Disease3-methylglutarylcarnitine (2) measurement

CPT2 SLC22A1

1.46e-03111552EFO_0800074
DiseaseLiver carcinoma

EPHX1 ADAMTS1 TST RUNX3 BCO2 MTOR SLC22A1 CDCA5 CDH13

1.50e-035071559C2239176
DiseaseFamilial dilated cardiomyopathy

PPCS SCN5A TAFAZZIN

1.61e-03441553C0340427
Diseaseureteral obstruction (biomarker_via_orthology)

ADAMTS1 MTOR PAK2

1.72e-03451553DOID:5199 (biomarker_via_orthology)
DiseaseGastric Adenocarcinoma

INSR EPHA2 TNK2

1.72e-03451553C0278701
Diseaseendometrial carcinoma (is_implicated_in)

RUNX3 CDH13

1.75e-03121552DOID:2871 (is_implicated_in)
Diseasebrain disease (is_implicated_in)

RANBP2 CPT2

1.75e-03121552DOID:936 (is_implicated_in)
DiseaseMajor Depressive Disorder

PCLO CMYA5 APRT PROM1 IKBKE MTOR

1.85e-032431556C1269683
DiseaseMammary Carcinoma, Human

ADAMTS1 APRT PGR PTPRD PER3 GUCY1A2 MTOR FGD5 KLHDC7A

1.90e-035251559C4704874
DiseaseMammary Neoplasms, Human

ADAMTS1 APRT PGR PTPRD PER3 GUCY1A2 MTOR FGD5 KLHDC7A

1.90e-035251559C1257931
DiseaseMammary Neoplasms

ADAMTS1 APRT PGR PTPRD PER3 GUCY1A2 MTOR FGD5 KLHDC7A

1.95e-035271559C1458155
Diseaseserum alanine aminotransferase measurement

RAPGEF6 PCLO INSR ARHGAP39 PPARD CMYA5 PARP6 MAP4K5 EPHA2 PISD USP3 TJP3

2.20e-0386915512EFO_0004735
DiseaseBreast Carcinoma

ADAMTS1 APRT PGR PTPRD PER3 GUCY1A2 MTOR FGD5 KLHDC7A

2.24e-035381559C0678222
DiseaseUnipolar Depression

PCLO CMYA5 APRT PROM1 IKBKE MTOR

2.54e-032591556C0041696
Diseaseglucose homeostasis measurement, glucose effectiveness measurement

MAP4K5 CDH13

2.75e-03151552EFO_0006833, EFO_0006896
Diseaselysophosphatidylcholine 14:0 measurement

GUCY1A2 MAP4K5

2.75e-03151552EFO_0010356
Diseasethird ventricle volume measurement

PTPRD GUCY1A2

2.75e-03151552EFO_0010335
Diseasepulse pressure measurement

PCDHA9 CRADD NEK10 INSR PCDHA7 PCDHA2 ADAMTS8 PPCS ULK3 PROM1 PTPRD ULK4 FGD5 CMAHP HS6ST3 CDH13

2.77e-03139215516EFO_0005763
DiseaseMetastatic melanoma

NEK10 MTOR MAST1

2.90e-03541553C0278883
Diseasecardiovascular disease

INSR SPTBN5 SCAF1 MAP4K5 EPHA2 FGD5 SIPA1L2 CDCA5

2.96e-034571558EFO_0000319
Diseasecancer (implicated_via_orthology)

PPCS RING1 RNF2 MTOR HSP90AA4P HSP90AB3P

3.01e-032681556DOID:162 (implicated_via_orthology)
DiseaseHOMA-B

ATP10A SLC22A1 NAV3

3.05e-03551553EFO_0004469
Diseaselinoleic acid measurement

PPARD RHD MAP4K5 SLC22A1 RFPL2

3.08e-031861555EFO_0006807
Diseasefocal segmental glomerulosclerosis

PPCS DNAH6

3.13e-03161552EFO_0004236
Diseasedental caries

PROM1 MTMR4 PTPRD CDH13 HSP90AA4P

3.15e-031871555EFO_0003819
Diseasediastolic blood pressure, alcohol drinking

NEK10 INSR CEP170 ULK4

3.53e-031181554EFO_0004329, EFO_0006336
DiseaseGlycogen storage disease

AGL GAA

3.54e-03171552cv:C0017919
Diseaseurate measurement, spine bone mineral density

COLCA1 PTPRD CDH13

3.55e-03581553EFO_0004531, EFO_0007701
Diseaseglycoprotein measurement

RUNX3 SCAF1 MAP4K5 SLC22A1

3.64e-031191554EFO_0004555
Diseaseinsulin resistance

PTPRD MTOR MAP4K5

3.73e-03591553EFO_0002614
Diseaseresponse to clozapine

PPARD CDH13

3.97e-03181552GO_0097338
DiseaseAcute Myeloid Leukemia, M1

EPHX1 RUNX3 JAK2 CTNNA1

4.34e-031251554C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

EPHX1 RUNX3 JAK2 CTNNA1

4.34e-031251554C1879321
DiseaseIGF-1 measurement

MAP1A CRADD ADAMTS8 JAK2 MAP4K5 SLC22A1 CMAHP PLK4

4.39e-034881558EFO_0004627
Diseaseportal hypertension (implicated_via_orthology)

JAK2 MTOR

4.42e-03191552DOID:10762 (implicated_via_orthology)
Diseasepuberty, height growth measurement

CRADD PRKG2

4.42e-03191552EFO_0001382, EFO_0005201
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

EPHX1 CTNNA1

4.42e-03191552C1333991
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

EPHX1 CTNNA1

4.42e-03191552C2936783
Diseaseserum dimethylarginine measurement

MYOM1 EPC1 CDH13

4.48e-03631553EFO_0005418
DiseaseMalignant neoplasm of breast

ADAMTS1 FAM131A APRT RHD PGR PTPRD PER3 GUCY1A2 MTOR TENM1 ZFYVE26 FGD5 KLHDC7A

4.49e-03107415513C0006142
Diseasecholangiocarcinoma (is_marker_for)

RUNX3 MUC4 MUC6

4.69e-03641553DOID:4947 (is_marker_for)
Diseaseresponse to COVID-19 vaccine, SARS-CoV-2 neutralizing antibody measurement

PTPRD GUCY1A2

4.90e-03201552EFO_0803359, EFO_0803362
DiseaseCardiomyopathies

PPARD SCN5A GAA TAFAZZIN

4.99e-031301554C0878544

Protein segments in the cluster

PeptideGeneStartEntry
SFLPRKFPSLRAVPA

BOP1

341

Q14137
DRVFDESLNFRKIPP

CEP170

1356

Q5SW79
FRARALDASKPLPVF

EPC1

6

Q9H2F5
PRRSPRISFFLEKEN

CDCA5

76

Q96FF9
FGIRARPSTPFFDLL

CFAP77

206

Q6ZQR2
REDRPSLPLFEAFTA

CPED1

666

A4D0V7
LRLAPDDSFLAPEFK

ADAMTS8

66

Q9UP79
VPDFSELFKERATAP

ATP13A1

231

Q9HD20
PFATSIRPLDTFRAL

EVX2

311

Q03828
LTPLDSLIDFKRFHP

GSDMA

21

Q96QA5
RTSPPVRAFAKELFL

ACAD9

31

Q9H845
ESSPSAPDRLFKIVF

CRACR2A

536

Q9BSW2
RRRKVLFEDPLFPAT

CAPN5

21

O15484
LQDIFKFARTSPVPR

CDH13

121

P55290
NSAAKSFPRRFVLPL

BCO2

401

Q9BYV7
SPVKTIEDFLRRFTP

ATP10A

601

O60312
KPEDRPTFVALRDFL

TNK2

371

Q07912
FRDISPVLKDPASFR

APRT

26

P07741
FNSTRLPKPSRDELF

CPT2

221

P23786
LRFFAPAILTPKLFD

RASAL1

471

O95294
RTPAFSPFVRVEKRD

RAI1

1591

Q7Z5J4
SPLASSPVRKNLFRF

RANBP2

2246

P49792
FIAESRPLDSRFPLE

PCDHA9

141

Q9Y5H5
PLASSPVRKNLFRFD

RGPD5

1271

Q99666
FLSEFKPDRALPIDR

ARHGAP36

76

Q6ZRI8
PLASSPVRKNLFRFD

RGPD8

1271

O14715
FFPERRPSPFLKRAE

ARHGAP39

266

Q9C0H5
KFLEAFFEEPPRRQS

RIMBP3B

1241

A6NNM3
KFLEAFFEEPPRRQS

RIMBP3C

1241

A6NJZ7
AALERIRSFSPLKEP

ADAMTS1

806

Q9UHI8
EPDFRPSFRAIIRDL

JAK2

791

O60674
RFPESRLLDSRFPLE

PCDHA2

141

Q9Y5H9
FIAESRPLDSRFPLE

PCDHA7

141

Q9UN72
VVFDSPRNRGLKEFP

PADI4

366

Q9UM07
VRRTVDFTSPLFKPA

MUC4

4331

Q99102
KDAFPTFSVQLRRGP

MUC6

76

Q6W4X9
ASALIDRPAPFFERS

EPB41L1

406

Q9H4G0
FFNVPEKLRLPDASR

MAP1A

136

P78559
DFSTKEFLPDPALVR

NLRC4

971

Q9NPP4
ATRREFFPTAPEKPL

GPR179

2261

Q6PRD1
SSAPPRTAFARLEEK

EDRF1

56

Q3B7T1
NFRPDDPARKTKALL

DNM1

316

Q05193
FSPRRAPFDLFENKK

HSP90AB3P

276

Q58FF7
RPAEPAFLARFKERV

KIAA1143

11

Q96AT1
LFSTAIPKGLAFRDP

IKBKE

381

Q14164
RFEDVPALRAFPDLK

C1orf109

56

Q9NX04
SFDRRFFPISKDQPR

EIF2B5

51

Q13144
LPAKPRPFFRSSSLD

PCLO

2386

Q9Y6V0
FPSERRNKPSTLDAL

PER3

66

P56645
RNRPLFKRLFPTDLF

NEK10

451

Q6ZWH5
AFEALKSRAVRPPAL

PDZD7

636

Q9H5P4
PDIASPTFRRLFGAK

NAV3

1241

Q8IVL0
KRLLFPRFFFVSDPV

DNAH8

1576

Q96JB1
LEASRALPAKPRAFT

FGD5

531

Q6ZNL6
TSNFPRECIRRFFPK

GBP6

216

Q6ZN66
RLIQAPSKFAFLRSP

KCNG1

286

Q9UIX4
PSKFAFLRSPLTLID

KCNG1

291

Q9UIX4
FKTRPEDFRDLSFPK

INSR

66

P06213
RDEPDIASKIPSRFF

ITPRID2

191

P28290
PRFVPRFNFSLKDLT

HS6ST3

121

Q8IZP7
SIERLFSFPAAKPKE

INF2

601

Q27J81
LNKPPEFSFEKARVR

PRKG2

136

Q13237
RRFSALLEPSRFSAP

MAST1

796

Q9Y2H9
RATARPAKPEDLFAF

MTMR4

116

Q9NYA4
ATSPLEEFKRAAVPR

SMPD4

396

Q9NXE4
LSDKIRFPSFLRTVP

GPRC6A

176

Q5T6X5
ALVPKEDSRFSAPRV

PGR

266

P06401
KVPLEARPVRFLDNF

PPCS

46

Q9HAB8
PEKLSPIFRDFLNRC

PAK2

466

Q13177
FSPEALKPLRDVFQR

GMPPA

186

Q96IJ6
EESPFLDPALRKRAV

CXXC1

311

Q9P0U4
RTELPDNLKALFRPF

DNAH6

1581

Q9C0G6
ELRSFGRTADFPPSK

IFT57

121

Q9NWB7
RIDKFRFTPPLEDSC

EPHX1

66

P07099
LASDFRKLDFSRPEP

COLCA1

96

Q6ZS62
VDPLSFSEERFRPSL

CTNNA1

291

P35221
RERATFEKLSRPPGF

ANKZF1

146

Q9H8Y5
LEFEPSRKPSRRAAI

FBXL8

76

Q96CD0
AFKRERPLVTESPTF

CEP126

401

Q9P2H0
FRISFFPKDPVELLR

FRMPD3

261

Q5JV73
RAPDSLKTLADFDPR

EPHA2

876

P29317
FPSKESERTLARPFD

CMYA5

2786

Q8N3K9
LPSRGPKAFDTFLDS

CRADD

61

P78560
LLAKLPPSRESAFRS

FAM131A

281

Q6UXB0
KETLRLFPSVPLFAR

CYP4V2

386

Q6ZWL3
FERNPFPDIATRKKL

DUXB

121

A0A1W2PPF3
ELRALSKVLPFFERP

ERO1A

311

Q96HE7
ETVARPLFLEFPKDS

GAA

721

P10253
LSRPSPFDLFIRKSP

IGHE

221

P01854
FLADSVSPRFVPKEL

KLHDC7A

736

Q5VTJ3
LPISELFSPDPRKAF

KNDC1

331

Q76NI1
LFSPDPRKAFLDRKN

KNDC1

336

Q76NI1
FTRDKRNLPFTPILA

SLC44A1

416

Q8WWI5
FVPRLAPFELLETRK

HSP90AA4P

146

Q58FG1
LFKPPTSDAEFLERL

PNMA1

91

Q8ND90
SPSFADLFRTPRLRK

SLC22A1

331

O15245
NIQFEPSDLRSKRPF

SLC38A9

26

Q8NBW4
RKFSLERPFRPSVTS

CARD11

641

Q9BXL7
LVSKRSLRPDPNFDA

RING1

91

Q06587
SKRSLRPDPNFDALI

RNF2

96

Q99496
FPDRILPRKFALTTK

MAP4K5

601

Q9Y4K4
FLLLSSPPAKEARFR

PARP6

446

Q2NL67
LLTFFLRTDAETPPR

PTPRD

11

P23468
FLAFLRRVKTCNPPD

PTPRD

1531

P23468
PLASSPVRKNIFRFD

RGPD1

1256

P0DJD0
RPFRLESLDIPFTKA

KIF17

1001

Q9P2E2
LPRLAAFRPSAFTDT

MTOR

396

P42345
SFTFIPRSREELPDN

GUCY1A2

671

P33402
KFRARFPDQPFIALE

NT5M

56

Q9NPB1
TKPFPDRFGDLERLR

RUNX3

191

Q13761
DRFQTRSFLAPVKPI

SPATA48

296

A4D263
LEFFVPPKASRPRLS

SH2B1

306

Q9NRF2
PSIRDVIAFPKSFRG

DARS2

596

Q6PI48
RPLSKEDTFEAVAPF

PSAPL1

151

Q6NUJ1
DKTRFSILPPKLFSD

RAPGEF6

681

Q8TEU7
EPEPSAFSFLSLRRE

SPATA2L

301

Q8IUW3
KSPVQLEEAPFSRRF

PPP1R12C

406

Q9BZL4
FLRSLRKPFSDIIEP

PPARD

316

Q03181
FSRNPTERFKTLPAV

TDRD9

816

Q8NDG6
TERFDLARALPKPTF

LRRTM3

366

Q86VH5
KFLEAFFEEPPRRQS

RIMBP3

1241

Q9UFD9
ELFPPLFVEAFTSRR

PRAMEF22

36

A3QJZ6
VQPRDFPEDTLRKFL

PROM1

66

O43490
DFADALSEPLRIAKP

SCN5A

1816

Q14524
AAIPRSTSFDRKLPD

SIPA1L2

1101

Q9P2F8
ILIFDRSPFLPEKRT

TENM1

936

Q9UKZ4
DSILKADPRVFFPSD

TEFM

306

Q96QE5
LALSADKRNFLRDPP

SYAP1

141

Q96A49
FSSPVRLAPEREFIK

PI4KB

316

Q9UBF8
ISEEERKTRSAPFFP

PLK4

786

O00444
LKRFENFIKSRPPFD

PRORP

391

O15091
VVPARLKRASAPTFD

RIPK4

361

P57078
AAFTIFRTQEKPPRL

SPTBN5

346

Q9NRC6
AVDFPLFPRRFAKTE

PIGW

146

Q7Z7B1
ALERKDFFSLPLPLA

BRINP2

101

Q9C0B6
DFLDLSFPKERPQRE

CMAHP

391

Q9Y471
SLAFPTKERAFDDIP

CHST12

136

Q9NRB3
DPFVRLISAFRSKFE

CHST12

246

Q9NRB3
VKPEAFLPFSAGRRA

CYP2D7

446

A0A087X1C5
DDIRKLDRFTEPPAF

PPP3CC

206

P48454
PRLAERLSPFLAESK

TNRC18

256

O15417
PSFNSALLRSPIERK

RHD

221

Q02161
KPFSALPVLERLRAE

TAFAZZIN

211

Q16635
EPSLKSRRIEGFPFA

IGSF9B

866

Q9UPX0
FSRDRESRSPFLKPD

SCAF1

866

Q9H7N4
DKEPLSSLRGFFPAT

WDR97

1016

A6NE52
LKSFFRKLPEPLFTD

ARHGAP23

981

Q9P227
QPLRKLPFRAFRTDA

PISD

36

Q9UG56
VRRDEIRPLSFEFTP

PPM1M

241

Q96MI6
PEIFRRAKFDRPEAT

TEDC1

36

Q86SX3
EERFRLEFFVPPKAS

SH2B2

231

O14492
FRSVSAEEPLRPFLA

RFPL2

331

O75678
VQADKPSFFTDRRKP

NT5DC2

296

Q9H857
PSFFTDRRKPFRKLD

NT5DC2

301

Q9H857
VFFIPESRPALKALR

TJP3

696

O95049
SRKFDPFLDLSLDIP

USP3

331

Q9Y6I4
TPRTAALALRFDKPI

TMEM245

36

Q9H330
EEKPFALFLPRATFV

TPRN

626

Q4KMQ1
SRPEPAVFKATLDRS

TST

146

Q16762
FQLPRRLSDSPVFDA

ZFP36L2

431

P47974
TDFPPSKISRDSEFR

ZP2

446

Q05996
AAREKFSRCLKPPFD

ZFYVE26

2081

Q68DK2
PLFSLPEARTRFTKS

THOC1

6

Q96FV9
TEDPSPETFRQLFRL

ZNF500

41

O60304
FRLENPTEFRPKSTL

ULK4

336

Q96C45
PPFASRSFSELEEKI

ULK3

211

Q6PHR2
SLFETPRKTREPFIL

VPS13D

1341

Q5THJ4
PFPGETFNREKFRSL

AGL

51

P35573
PVKSPRFALFDLAEG

MYOM1

691

P52179