Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmelanocortin receptor activity

MC4R MC5R MC1R

2.32e-086223GO:0004977
GeneOntologyMolecularFunctionmelanocyte-stimulating hormone receptor activity

MC4R MC1R

3.47e-063222GO:0004980
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GPR50 MC4R TLR10 MC5R GPR160 CHRNE TAS2R19 MC1R

5.90e-051353228GO:0004888
GeneOntologyMolecularFunctionhormone binding

MC4R MC5R MC1R

1.91e-04103223GO:0042562
GeneOntologyMolecularFunctionG protein-coupled receptor activity

GPR50 MC4R MC5R GPR160 TAS2R19 MC1R

3.00e-04884226GO:0004930
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

MC4R MC5R MC1R

4.05e-04133223GO:0008528
GeneOntologyMolecularFunctionpeptide receptor activity

MC4R MC5R MC1R

4.71e-04140223GO:0001653
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA10 CFTR

1.32e-0349222GO:0140359
GeneOntologyMolecularFunctiongated channel activity

HVCN1 CFTR CHRNE

5.64e-03334223GO:0022836
GeneOntologyMolecularFunctionubiquitin protein ligase binding

MC4R TMBIM6 MC1R

5.78e-03337223GO:0031625
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA10 CFTR

6.35e-03109222GO:0042626
GeneOntologyMolecularFunctionubiquitin-like protein ligase binding

MC4R TMBIM6 MC1R

6.83e-03358223GO:0044389
GeneOntologyBiologicalProcessregulation of intracellular pH

FASLG HVCN1 CFTR

1.33e-0494223GO:0051453
GeneOntologyBiologicalProcessmonoatomic cation transport

TMBIM6 FASLG CD63 HVCN1 CFTR CHRNE TSPAN18

1.39e-041157227GO:0006812
GeneOntologyBiologicalProcessregulation of cellular pH

FASLG HVCN1 CFTR

1.64e-04101223GO:0030641
GeneOntologyCellularComponentendocytic vesicle

HEATR5B HVCN1 CFTR OCLN

6.31e-04384224GO:0030139
GeneOntologyCellularComponentlysosome

FASLG CD63 USE1 CFTR OCLN

1.32e-03811225GO:0005764
GeneOntologyCellularComponentlytic vacuole

FASLG CD63 USE1 CFTR OCLN

1.32e-03811225GO:0000323
MousePhenoenlarged ileum

CFTR TMEM248

8.34e-064172MP:0009483
MousePhenoabnormal salivary gland morphology

FASLG CFTR OCLN

1.03e-0477173MP:0000613
DomainMelcrt_ACTH_rcpt

MC4R MC5R MC1R

2.44e-086213IPR001671
DomainMelancort_rcpt

MC4R MC5R

3.61e-063212IPR001908
Domain7TM_GPCR_Srsx

GPR50 MC4R MC5R MC1R

6.78e-06112214SM01381
DomainTetraspanin_CS

CD63 TSPAN18

2.50e-0421212IPR018503
DomainTM4_1

CD63 TSPAN18

3.85e-0426212PS00421
DomainTetraspanin

CD63 TSPAN18

5.85e-0432212IPR000301
DomainTetraspanin_EC2

CD63 TSPAN18

5.85e-0432212IPR008952
DomainTetraspannin

CD63 TSPAN18

6.23e-0433212PF00335
DomainTetraspanin/Peripherin

CD63 TSPAN18

6.23e-0433212IPR018499
DomainGPCR_Rhodpsn_7TM

GPR50 MC4R MC5R GPR160 MC1R

7.38e-04670215IPR017452
DomainG_PROTEIN_RECEP_F1_1

GPR50 MC4R MC5R GPR160 MC1R

8.16e-04685215PS00237
DomainG_PROTEIN_RECEP_F1_2

GPR50 MC4R MC5R GPR160 MC1R

8.49e-04691215PS50262
DomainGPCR_Rhodpsn

GPR50 MC4R MC5R GPR160 MC1R

8.54e-04692215IPR000276
DomainABC_transporter_CS

ABCA10 CFTR

1.01e-0342212IPR017871
DomainABC_TRANSPORTER_2

ABCA10 CFTR

1.32e-0348212PS50893
DomainABC_tran

ABCA10 CFTR

1.32e-0348212PF00005
DomainABC_TRANSPORTER_1

ABCA10 CFTR

1.37e-0349212PS00211
DomainABC_transporter-like

ABCA10 CFTR

1.43e-0350212IPR003439
Domain7tm_1

GPR50 MC4R MC5R MC1R

6.26e-03677214PF00001
DomainAAA+_ATPase

ABCA10 CFTR

1.13e-02144212IPR003593
DomainAAA

ABCA10 CFTR

1.13e-02144212SM00382
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

GPR50 MC4R MC5R CHRNE MC1R

1.80e-05272185M13380
PathwayREACTOME_TRANSCRIPTIONAL_AND_POST_TRANSLATIONAL_REGULATION_OF_MITF_M_EXPRESSION_AND_ACTIVITY

MC4R MC5R MC1R

3.50e-0551183M48267
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

GPR50 MC4R MC5R MC1R

7.77e-05186184MM15994
PathwayWP_GPCRS_PEPTIDE

MC4R MC5R MC1R

9.07e-0570183MM15959
PathwayWP_PEPTIDE_GPCRS

MC4R MC5R MC1R

1.11e-0475183M39696
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

GPR50 MC4R MC5R MC1R

2.82e-04260184M39397
PathwayWP_GPCRS_NONODORANT

GPR50 MC4R MC5R MC1R

3.08e-04266184MM15843
PathwayREACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT

MC4R MC5R MC1R

6.58e-04137183M48232
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

MC4R MC5R MC1R

7.46e-04143183MM15055
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

MC4R MC5R MC1R

9.78e-04157183M4904
PathwayKEGG_ABC_TRANSPORTERS

ABCA10 CFTR

1.41e-0344182M11911
PathwayREACTOME_GPCR_LIGAND_BINDING

MC4R MC5R TAS2R19 MC1R

1.86e-03430184MM15160
PathwayREACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

MC4R MC5R MC1R

1.88e-03197183M12289
PathwayREACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

MC4R MC5R MC1R

1.88e-03197183MM14970
PathwayWP_11P112_COPY_NUMBER_VARIATION_SYNDROME

CD63 TSPAN18

2.28e-0356182M48075
PathwayREACTOME_GPCR_LIGAND_BINDING

MC4R MC5R TAS2R19 MC1R

2.44e-03463184M507
Pubmed

Proteochemometric mapping of the interaction of organic compounds with melanocortin receptor subtypes.

MC4R MC5R MC1R

8.78e-10422315470082
Pubmed

Adrenocorticotropic hormone directly stimulates testosterone production by the fetal and neonatal mouse testis.

MC4R MC5R MC1R

2.19e-09522312865302
Pubmed

Molecular cloning, expression, and characterization of a fifth melanocortin receptor.

MC4R MC5R MC1R

2.19e-0952238185570
Pubmed

Biphasic effect of melanocortin agonists on metabolic rate and body temperature.

MC4R MC5R MC1R

4.39e-09622324981835
Pubmed

Melanocortin receptor binding determinants in the agouti protein.

MC4R MC5R MC1R

4.39e-0962239454589
Pubmed

MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family.

MC4R MC5R MC1R

7.68e-09722319329486
Pubmed

Effects of recombinant agouti-signaling protein on melanocortin action.

MC4R MC5R MC1R

7.68e-0972239058374
Pubmed

The structure and evolution of the melanocortin and MCH receptors in fish and mammals.

MC4R MC5R MC1R

7.68e-09722312620396
Pubmed

Agouti/melanocortin interactions with leptin pathways in obesity.

MC4R MC5R MC1R

1.23e-0882239763877
Pubmed

A melanocortin receptor 1 and 5 antagonist inhibits sebaceous gland differentiation and the production of sebum-specific lipids.

MC5R MC1R

3.82e-07222221602033
Pubmed

Melanocortin receptors 1 and 5 might mediate inhibitory effects of α-melanocyte-stimulating hormone on antigen-induced chronic allergic skin inflammation in IgE transgenic mice.

MC5R MC1R

3.82e-07222222437312
Pubmed

Metal ion-mediated agonism and agonist enhancement in melanocortin MC1 and MC4 receptors.

MC4R MC1R

3.82e-07222212244039
Pubmed

Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5.

MC5R MC1R

1.15e-06322225860801
Pubmed

Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells.

FASLG CD63

1.15e-06322219079288
Pubmed

Evidence indicating that the TM4, EL2, and TM5 of the melanocortin 3 receptor Do not participate in ligand binding.

MC5R MC1R

1.15e-0632228954958
Pubmed

Mutational analysis of melanocortin-4 receptor, agouti-related protein, and alpha-melanocyte-stimulating hormone genes in severely obese children.

MC4R MC1R

1.15e-06322211487744
Pubmed

A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism.

MC4R MC1R

1.15e-06322212165561
Pubmed

Detection of functionally active melanocortin receptors and evidence for an immunoregulatory activity of alpha-melanocyte-stimulating hormone in human dermal papilla cells.

MC4R MC1R

1.15e-06322216081629
Pubmed

Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5.

MC4R MC5R

1.15e-06322217482720
Pubmed

A novel MC4R deletion coexisting with FTO and MC1R gene variants, causes severe early onset obesity.

MC4R MC1R

1.15e-06322227394708
Pubmed

Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas.

MC4R MC1R

1.15e-06322219737927
Pubmed

Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor.

MC4R MC1R

1.15e-0632227935841
Pubmed

Novel binding motif of ACTH analogues at the melanocortin receptors.

MC4R MC1R

2.29e-06422219743876
Pubmed

The regulated secretory pathway in CD4(+) T cells contributes to human immunodeficiency virus type-1 cell-to-cell spread at the virological synapse.

FASLG CD63

3.82e-06522221909273
Pubmed

Further evidence for the role of ENPP1 in obesity: association with morbid obesity in Finns.

MC4R MC5R

5.72e-06622218551113
Pubmed

Mapping of the ACTH, MSH, and neural (MC3 and MC4) melanocortin receptors in the mouse and human.

MC4R MC1R

1.07e-0582227949735
Pubmed

Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.

MC4R MC5R MC1R

1.17e-057022312036966
Pubmed

Quantitative trait loci for obesity- and diabetes-related traits and their dietary responses to high-fat feeding in LGXSM recombinant inbred mouse strains.

GPR50 MC1R

1.05e-042422215561968
Pubmed

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.

TMBIM6 FASLG

1.14e-042522226582200
Pubmed

Potential genetic modifiers of the cystic fibrosis intestinal inflammatory phenotype on mouse chromosomes 1, 9, and 10.

FASLG CFTR

1.76e-043122215921521
InteractionTJP3 interactions

FASLG CFTR OCLN

5.09e-0715223int:TJP3
InteractionASIP interactions

MC4R MC5R MC1R

6.26e-0716223int:ASIP
InteractionMC1R interactions

MC4R CFTR MC1R

1.72e-0622223int:MC1R
InteractionMSX1 interactions

MC4R MC5R MC1R

7.88e-0636223int:MSX1
InteractionPOMC interactions

MC4R MC5R MC1R

1.66e-0546223int:POMC
InteractionFUT7 interactions

TLR10 GPR160

3.17e-058222int:FUT7
InteractionSCN3B interactions

TMBIM6 OSTC USE1 OCLN

7.78e-05214224int:SCN3B
InteractionAGRP interactions

MC4R MC5R

1.03e-0414222int:AGRP
InteractionVPS4A interactions

USE1 CFTR TMEM248

1.29e-0491223int:VPS4A
InteractionPZP interactions

CFTR TMEM248

1.53e-0417222int:PZP
InteractionSYNE4 interactions

CFTR TMEM248 OCLN

1.76e-04101223int:SYNE4
Cytoband12q12-q13

TMBIM6 CD63

6.13e-06822212q12-q13
GeneFamilyMelanocortin receptors

MC4R MC5R MC1R

9.83e-095193236
GeneFamilyCD molecules|Tetraspanins

CD63 TSPAN18

5.42e-0433192768
GeneFamilyG protein-coupled receptors, Class A orphans

GPR50 GPR160

3.00e-0378192262
GeneFamilyADAM metallopeptidase domain containing|CD molecules

TLR10 FASLG CD63

7.68e-03394193471
CoexpressionMORI_PLASMA_CELL_UP

OSTC GPR160 TMEM248

1.24e-0554223MM597
CoexpressionMORI_PLASMA_CELL_UP

OSTC GPR160 TMEM248

1.24e-0554223M1487
ToppCelldroplet-Marrow-nan-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD63 HVCN1 GPR160 TMEM248

1.91e-061852243dcafbd02b65a2befbb6e6288cb2591e721cddb6
ToppCelldroplet-Marrow-BM-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD63 HVCN1 GPR160 TMEM248

1.91e-061852244157cc14b06bb99ee67ac1526622cf546e727efc
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPR50 LHFPL3 TSPAN18

1.64e-051012236523c314166dcf66c3ed13c02ca4b886b068e5b8
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MC5R CD63 CFTR

4.08e-05137223d346086f42d8f04d3fa67fe696834284acdc7080
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CD63 CFTR TSPAN18

5.13e-051482239205b26e0d042b342cc643cda0f4f3f8bb392d00
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FASLG CD63 ABCA10

5.45e-0515122309405a450af3ea246d9685a6d3137dfaec80e9bf
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MC5R CD63 CFTR

6.83e-05163223ec9a20cfe0d69430f9c68cddd1ab0e4a3e4554b8
ToppCelldroplet-Fat-Scat-21m-Lymphocytic-T_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MC4R FASLG CHRNE

7.48e-0516822399343f7a76ff70a2252c365d527f9c8ae16b8571
ToppCell367C-Lymphocytic-B_cell-|367C / Donor, Lineage, Cell class and subclass (all cells)

MC4R TLR10 HVCN1

7.48e-05168223f4414d462d35abd00e3c1446302d7060f8a48d48
ToppCell367C-Lymphocytic-B_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

MC4R TLR10 HVCN1

7.48e-051682231943ae24ff90218b8c2c10b4102b5007ae35fc85
ToppCelldroplet-Lung-nan-3m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD63 HVCN1 LHFPL3

7.61e-05169223da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FASLG HVCN1 CHRNE

7.61e-05169223d721dbb317a88113b4f76688111908d00f23e899
ToppCelldroplet-Lung-nan-3m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD63 HVCN1 LHFPL3

7.61e-05169223a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CD63 CFTR TSPAN18

7.74e-0517022314aa86a4f526ed6986afcb28c49225522055550c
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FASLG HVCN1 CHRNE

7.88e-051712232e7cc311005958af52f39ca6c310c85b43a85aaf
ToppCell356C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HEATR5B SAMD8 OCLN

7.88e-051712233d26ef58fe5231373d7df9ac79d225546918cf82
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FASLG HVCN1 CHRNE

7.88e-051712234b599f953c8e5b947b2c8bbbf7fe6f9dc388e336
ToppCell356C-Lymphocytic-ILC-ILC-2|ILC / Donor, Lineage, Cell class and subclass (all cells)

HEATR5B SAMD8 OCLN

8.01e-051722234977e1f4deae781750e27a8054deccd336cfb74a
ToppCellsevere-B_memory|severe / disease stage, cell group and cell class

TLR10 HVCN1 ABCA10

8.15e-051732233a987ac53a0136cc4c70ce8b901a15fc00c795e1
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR160 CFTR OCLN

8.29e-05174223e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR160 CFTR OCLN

8.29e-05174223ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCellHSPCs-Neutro_prog.|HSPCs / Lineage and Cell class

CD63 HVCN1 GPR160

9.17e-05180223328192f4678dcdc01c806362b225e770d23498d6
ToppCelldroplet-Lung-LUNG-30m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD63 HVCN1 SAMD8

9.32e-051812238fcdab61fad2efd324d2b27c58f5a594f1dc15de
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MC4R CD63 LHFPL3

9.32e-051812231037051eb82313c13346617b33f3c4c648181c4d
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-2|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TLR10 HVCN1 GPR160

9.32e-0518122375035a3211e524bb659b82e6979f7d3a3121ae70
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TMBIM6 FASLG CD63

9.47e-05182223c6172aca2475bf0948a78e39f0dae6388504a915
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD63 HVCN1 SAMD8

9.47e-05182223be48ce85991bceeff938ba080e6bf9cc62176b05
ToppCelldroplet-Lung-nan-21m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD63 HVCN1 SAMD8

1.01e-041862238f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCelldroplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD63 HVCN1 SAMD8

1.01e-04186223f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCelldroplet-Marrow-nan-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD63 HVCN1 GPR160

1.01e-04186223332931f92352b464c7f23aeebf313cf7db6d499c
ToppCelldroplet-Marrow-BM-1m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD63 HVCN1 TMEM248

1.03e-041872236be99f71532b7d679d1287ea1bb08245d9538db7
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MC4R MC5R LHFPL3

1.04e-04188223006db2c2c44971ca9241c582bc89f258c785f5ed
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MC4R MC5R LHFPL3

1.04e-04188223d0e6fb4a3b3d79d3512b5500062ea285495ae526
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD63 HVCN1 SAMD8

1.06e-0418922398f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD63 HVCN1 SAMD8

1.06e-04189223f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TLR10 HVCN1 GPR160

1.08e-04190223a7498fe55b7810c482291db782dc5282675d246a
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TLR10 HVCN1 GPR160

1.08e-04190223e63945fa1dcd58bee129f1dd0c23b64a76241554
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TLR10 HVCN1 GPR160

1.08e-04190223fa65bc5a178ae0c80a9bd4b282e4539493128a64
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TMBIM6 CD63 CFTR

1.09e-041912238b34e06c398056e857a10c7653c70c0b1f181692
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

TMBIM6 HVCN1 SAMD8

1.09e-041912237bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

TMBIM6 CD63 HVCN1

1.09e-0419122378ad7c555409ce1391bce406bc0f3ef575329ece
ToppCellMS-NK|MS / Condition, Cell_class and T cell subcluster

FASLG CD63 HVCN1

1.11e-04192223f44f5dd30db169fdd16c9d706d17ad44907a17af
ToppCellMS-NK-|MS / Condition, Cell_class and T cell subcluster

FASLG CD63 HVCN1

1.11e-04192223f97f5f8226f5c65ca93072ef35d753231bee2490
ToppCellBasal-basal-1|World / Class top

TMBIM6 CD63 USE1

1.14e-04194223b870f2d856e08c5c3596ca9da538eb8c93a7c062
ToppCellmetastatic_Brain-B_lymphocytes-Plasma_cells|B_lymphocytes / Location, Cell class and cell subclass

TMBIM6 CD63 OSTC

1.14e-0419422369828d24b3e182f26aa15eb0ae5aa21c640c2922
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMBIM6 CD63 CFTR

1.16e-04195223576142b4e75457c0973051bccc4163bd624496af
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMBIM6 CD63 CFTR

1.16e-041952238f151066ad3ebd9661ea0b733f03c2ce1518f9ad
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMBIM6 CD63 CFTR

1.16e-041952232a9a36df1dbc4eac77a8ddbe939ec8a8d6c41464
ToppCellVE-NK|VE / Condition, Cell_class and T cell subcluster

FASLG CD63 HVCN1

1.20e-04197223cae6ff8763501e7a5897b50188ac2640d65a47c0
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR160 CFTR OCLN

1.20e-041972235027787ab3ce60e1ddcb99e3a01f40bb07b05804
ToppCell5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR160 CFTR OCLN

1.20e-041972236ee6939c492bedf1f96a715da7a26a4c55a7c36f
ToppCellVE-NK-|VE / Condition, Cell_class and T cell subcluster

FASLG CD63 HVCN1

1.20e-04197223ee89b8521fb4faaed9e4d39f7171e45eccf38b00
ToppCellnormal_Lymph_Node-T/NK_cells-NK|T/NK_cells / Location, Cell class and cell subclass

FASLG CD63 HVCN1

1.22e-0419822375e94298bf03d755fef46df685437d0d29fdbca9
ToppCellmoderate-Lymphoid-CTL|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TMBIM6 FASLG CD63

1.22e-041982230a868098b1ee4b28b2149ed766acb09e9c0ce14c
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFTR LHFPL3 OCLN

1.23e-04199223725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellSigmoid-B_cell|Sigmoid / Region, Cell class and subclass

CD63 OSTC GPR160

1.23e-04199223997ee1b622b1e349d5e98026afbc4f8d283b2136
ToppCellSigmoid-(2)_B_cell-(20)_B_cell_IgA_Plasma|Sigmoid / shred on region, Cell_type, and subtype

CD63 OSTC GPR160

1.23e-04199223f3c583f8521f63834d1afbf8b07940fee7712f9a
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR160 CFTR OCLN

1.23e-041992239d24223b571fba202455c5bd49bd79530abf09c0
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR160 CFTR OCLN

1.23e-04199223722b9ebf7e47c361a7f192689a8d46947ec62b45
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR160 CFTR OCLN

1.23e-04199223c9bd712cf401aec256a2cfaec5b580209e52c265
ToppCellSigmoid-(2)_B_cell|Sigmoid / shred on region, Cell_type, and subtype

CD63 OSTC GPR160

1.23e-04199223646960845ede4c5b00cdfe73051d5d4577648bf8
ToppCellTransverse-B_cell-B_cell_IgA_Plasma|Transverse / Region, Cell class and subclass

CD63 OSTC GPR160

1.23e-04199223ea65cadaf464ff4c1040fceb5f3724706f8447c1
ToppCell(2)_B_cell|World / shred on Cell_type and subtype

CD63 HVCN1 GPR160

1.23e-04199223751cfdbc873390bd03837a57367a290f34d53f38
ToppCellSigmoid-B_cell-B_cell_IgA_Plasma|Sigmoid / Region, Cell class and subclass

CD63 OSTC GPR160

1.23e-04199223634e0b614ab45e7520da67375b3498db5442b7ae
ToppCellTransverse-(2)_B_cell-(20)_B_cell_IgA_Plasma|Transverse / shred on region, Cell_type, and subtype

CD63 OSTC GPR160

1.23e-041992238caaa08b046f766af298d03961ccac6e4569e2a6
ToppCellSepsis-Bac-SEP-Lymphocyte-B-B_naive|Bac-SEP / Disease, condition lineage and cell class

TLR10 HVCN1 GPR160

1.25e-04200223d377227314a4684d1bad15a13d87b1fa74b998f1
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR160 CFTR OCLN

1.25e-04200223eef5f6bd9ff5d985def8befcf45786234317f144
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR160 CFTR OCLN

1.25e-042002234b1ae9f71f0fe998b06fa580885572d1fc1544e2
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Macroglial-Glia_progenitor_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

TMBIM6 CD63 OSTC

1.25e-042002234859fbe663ae9372fc8ed3b4e1fa301e06621a31
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-BMP_responsible_cell|5w / Sample Type, Dataset, Time_group, and Cell type.

CD63 OSTC GPR160

1.25e-04200223ce8a3a8367bafdfabc7c2f96b003aa99526a54e4
ToppCell(21)_B_cell_IgG_Plasma|World / shred on Cell_type and subtype

CD63 OSTC GPR160

1.31e-0420322315055e1b1017afbdb2a567972cbb976deb7d4e6a
ToppCell(20)_B_cell_IgA_Plasma|World / shred on Cell_type and subtype

CD63 OSTC GPR160

1.33e-04204223fcca2135876031644a81d4aa3bc04145558f7745
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Pcdh11x_(Neuron.Gad1Gad2.Synpr-Pcdh11x)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GPR50 FASLG

3.84e-0459222439a9d56eeecccd70a4defb430e228329655cb80
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Pcdh11x_(Neuron.Gad1Gad2.Synpr-Pcdh11x)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GPR50 FASLG

3.84e-045922250432c7b52fd197e8856ba0296c34cf66a2faaf5
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Slco3a1_(Slco3a1)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GPR50 CHRNE

6.20e-0475222574ed1836f6bf5fa38a53af0a05fa4437f68f36b
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Slco3a1_(Slco3a1)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GPR50 CHRNE

6.20e-047522245f7861bfeb1c6371b73cf2ea527801342e534bc
ToppCellControl-CD8+_T|Control / Disease group and Cell class

FASLG CD63

1.01e-039622214e53fd2df39ac9d0b9cdc8b7ca2e95e53ac8bfe
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPR50 TSPAN18

1.16e-03103222d8965b338b90ddc0686ea0d94e9a330128566c39
ToppCellMild-Myeloid-Macrophages-|Mild / Condition, Lineage, Cell class and cell subclass

MC5R FASLG

1.63e-03122222b837456a6a236add2c0005cb3ca71568d631014e
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MC5R LHFPL3

1.68e-0312422236dfc702a570e1a1a6dde09f38badf9023ea7287
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-mesenchymal_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MC5R CD63

1.73e-03126222c3261ea8726400de87f1c8a5a5134ba2b2884f66
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Th_Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MC4R CD63

1.73e-031262223a14d4eb8803827946c36faeeb7ae2913418d421
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nts|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MC4R CD63

1.76e-03127222ace2944328529fa029ee56c7ad3b0f283511d3bb
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic-plasmablast|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TLR10 MC1R

1.79e-031282223c810fc4934dee4de2b8b64a2e152547b08c6f8d
ToppCellCerebellum-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nrgn_(Inferior_colliculus)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

MC4R CFTR

1.79e-031282229a800beca5cfc7b41f5eed500d45064cfa61c5de
ToppCellCerebellum-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nrgn_(Inferior_colliculus)|Cerebellum / BrainAtlas - Mouse McCarroll V32

MC4R CFTR

1.79e-03128222920ede29f3de68e4d08644a1da53849e0c0973fb
ToppCellCOVID-19-B_cells-B_cells|COVID-19 / group, cell type (main and fine annotations)

TLR10 HVCN1

1.84e-03130222267b06a0db31e2664cf595cd737402da07ab51cd
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Col15a1_Pde1a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CD63 TSPAN18

1.84e-0313022256b9c3325e011f1dbaf9efc71bd6e1af4f96fda6
ToppCellLymphoid-NK_cells|World / shred on cell class and cell subclass (v4)

FASLG CHRNE

1.87e-03131222b0b62392d1637601115e85f5584fdcd5dbd0c778
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sncg|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPR50 TSPAN18

1.93e-03133222840e8240db29cd21ed9830843c0fa6d65b8f300a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Col15a1_Pde1a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CD63 TSPAN18

1.96e-03134222d63fff23040eada31bc35ba1e05b7c6a663e0037
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp4_Mab21l1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MC5R CD63

2.01e-031362229cf076597e6fd9390850fda259daa13022f15893
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B0|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

TSPAN18 TAS2R19

2.07e-031382222709fb83dfe6c2e27050b08b678a6d6b25d47906
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA10 CHRNE

2.13e-031402225e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPR50 CD63

2.19e-03142222ed91d2ef4c346f7e1a5402846e2a34cee19c24d1
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CD63 CFTR

2.25e-031442220322fef818a963be00535d5f141f028d43de5c6a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CD63 TSPAN18

2.28e-0314522278f5f4b96420c7f391e4d32a9ed151ed95fad90b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CD63 CFTR

2.28e-03145222590ba937c741ae67460f303eca88b1cd3ac87f64
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TLR10 OCLN

2.41e-03149222a85a051e0d82430160967e72fa04b55f43e84513
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FASLG GPR160

2.41e-03149222efa30fcd9370f98eb7445f295eb4d0305ff455c3
Drugindole

MC4R MC5R MC1R

9.35e-0810223ctd:C030374
DrugLys-pro-val

MC4R MC5R MC1R

9.35e-0810223CID000125672
Drug4pal

MC4R MC5R MC1R

8.83e-0720223CID005748175
DrugActh (4-10)

MC4R MC5R MC1R

1.03e-0621223CID000123787
DrugActh(11-24)

MC4R MC5R MC1R

1.19e-0622223CID003037130
DrugShu 9119

MC4R MC5R MC1R

2.01e-0626223CID006440621
Drug2-thienylalanine

MC4R MC5R MC1R

2.26e-0627223CID000091444
Drugpentazocine HCl

MC4R MC5R MC1R

4.60e-0634223CID000004736
DrugAH 21-132

MC4R MC5R MC1R

5.96e-0637223CID003035793
Drugembitol

MC4R MC1R

8.90e-065222CID000005928
Drug1-aminoanthracene

MC4R MC5R MC1R

1.01e-0544223CID000011885
DrugIodogen

MC4R MC5R MC1R

1.01e-0544223CID000040065
Drug2-oxopiperazine

MC4R MC1R

1.33e-056222CID000231360
DrugHis-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2

MC4R MC1R

1.33e-056222CID003010021
Drugmelanotan II

MC4R MC5R MC1R

1.68e-0552223CID000092432
DrugActh (6-9)

MC4R MC1R

1.87e-057222CID000160744
DrugHaatpln

MC4R MC1R

3.20e-059222CID005487257
Druglysine salicylate

MC4R MC1R

3.20e-059222CID003080858
DrugHis-D-Trp-D-Lys-Trp-D-Phe-Lys-NH2

MC4R MC1R

4.88e-0511222CID005311279
DrugL-368,899

MC4R MC1R

4.88e-0511222CID000132857
Drugnitroparacetamol

FASLG CFTR

5.85e-0512222CID006918532
Drugmelanin

MC4R MC5R CD63 MC1R

6.11e-05227224CID006325610
DrugBim 22015

MC4R MC1R

6.91e-0513222CID000132380
DrugD90A

MC4R FASLG MC1R

7.35e-0585223CID000023715
DrugAC1L9NBR

MC4R CFTR MC1R

9.30e-0592223CID000449625
DrugPapaverine

CFTR OCLN

1.06e-0416222ctd:D010208
DrugR-5

MC4R MC5R

1.06e-0416222CID011742733
DrugHp 228

MC4R MC1R

1.20e-0417222CID000130595
Drugkpv

MC4R MC1R

1.20e-0417222CID013294447
Drugisocaproaldehyde

MC4R MC5R

1.35e-0418222CID000000129
Drugsuccinamide

MC4R MC1R

1.35e-0418222CID000008036
Drug6-Formyltetrahydropterin

MC4R MC1R

1.51e-0419222CID011841000
DrugR-4

MC4R MC5R

1.51e-0419222CID009800976
Drugthulium

MC4R CFTR MC1R

1.62e-04111223CID000023961
Drugdeoxycorticosterone

MC4R MC5R MC1R

1.62e-04111223CID000006166
Drugcompound 2a

MC4R MC1R

1.68e-0420222CID000398803
DrugAC1L1UOQ

MC4R MC5R

1.68e-0420222CID000010197
Drugbeta-methylphenylalanine

MC4R MC1R

1.85e-0421222CID000064808
DrugAC1NST48

FASLG CD63 USE1 CFTR MC1R

2.17e-04594225CID005315496
DrugPT 141

MC4R MC1R

2.23e-0423222CID006451163
DrugPL 0

MC4R MC1R

2.43e-0424222CID000016157
DrugA-26

MC4R MC5R

2.64e-0425222CID000037120
Drugaminoglutethimide

MC4R MC5R MC1R

3.02e-04137223CID000002145
Drugprocaine

CFTR CHRNE MC1R

4.17e-04153223CID000004914
Drug1q1m

MC4R MC5R

4.34e-0432222CID000447994
Drugcorticosterone

MC4R TLR10 MC5R MC1R

4.45e-04381224CID000005753
Drugcolchine

MC4R CFTR CHRNE MC1R

4.54e-04383224CID000002833
DrugMZ-m

FASLG CFTR

4.62e-0433222CID000001798
DrugModrenal

MC4R MC5R

4.91e-0434222CID000026163
DrugS-Nitrosoglutathione

FASLG CFTR

4.91e-0434222ctd:D026422
Drugaldosterone

MC4R MC5R CFTR MC1R

5.19e-04397224CID000005839
DrugCPAs

MC4R MC5R

5.20e-0435222CID000016770
Drugnaphthalene

MC4R MC5R CFTR MC1R

5.86e-04410224ctd:C031721
DrugAPAs

MC4R MC5R

6.46e-0439222CID000004649
Drug4-amino 5-hydroxy pentanoic acid

MC4R MC1R

6.46e-0439222CID005326858
DrugAC1Q6S1O

MC4R MC1R

6.80e-0440222CID000000623
Drugvinblastine

CFTR CHRNE MC1R

7.72e-04189223CID000013342
DrugHydralazine

HEATR5B FASLG CD63 TSPAN18 TMEM248

7.82e-04786225ctd:D006830
Drugtetrahydropyran

MC4R MC1R

8.60e-0445222CID000008894
DrugPicrotoxinin [17617-45-7]; Up 200; 13.6uM; MCF7; HT_HG-U133A

MC5R FASLG CHRNE

8.83e-041982232816_UP
DrugAC1L9NAZ

MC4R CFTR MC1R

8.83e-04198223CID000449606
Drugglycidol

FASLG GPR160 CFTR TSPAN18

9.46e-04466224ctd:C004312
Diseasemelanoma (is_implicated_in)

FASLG MC1R

2.93e-0434222DOID:1909 (is_implicated_in)
Diseasecystic fibrosis (is_marker_for)

FASLG CFTR

9.77e-0462222DOID:1485 (is_marker_for)
Diseasepancreatic cancer (is_implicated_in)

FASLG CFTR

3.14e-03112222DOID:1793 (is_implicated_in)
Diseasechronic lymphocytic leukemia

MC4R LHFPL3

3.53e-03119222EFO_0000095

Protein segments in the cluster

PeptideGeneStartEntry
MRIEMIFVIFFIAVT

CFTR

1101

P13569
CFIFIMSIFMALVIT

ABCA10

186

Q8WWZ4
RFLIFVMVVATLIVM

CHRNE

306

Q04844
VCVLLSFFMARVFMR

OSTC

126

Q9NRP0
RILSMLIIVMCIAIF

OCLN

66

Q16625
CLVVFFLAMLVLMAV

MC1R

191

Q01726
CLMITFAIFLSLIML

CD63

81

P08962
LVITFFMLLSAVCVM

FAM189A1

91

O60320
ILVFFMMEIIFKLFV

HVCN1

146

Q96D96
ALIIFMFCAMVITIV

GPR50

26

Q13585
SFFMVMILFVAFITC

GPR160

186

Q9UJ42
LVFATMELLMFILVR

HEATR5B

1711

Q9P2D3
FLDFITVFRKLMMIL

TMBIM6

211

P55061
SAVIICLITMFFTML

MC4R

191

P32245
VILCLISMFFAMLFL

MC5R

186

P33032
MMCFLLIISSILVVF

TAS2R19

1

P59542
FLFVMVITMFCYAVI

TMEM248

276

Q9NWD8
MRLIRNIYIFCSIVM

TLR10

1

Q9BXR5
MGTVFLLRCFTMFVT

SAMD8

236

Q96LT4
AMLIIVCFIFISMIL

USE1

236

Q9NZ43
VCFIFISMILFIRIM

USE1

241

Q9NZ43
LCLLVMFFMVLVALV

FASLG

81

P48023
AIELFAMIFAMCLFR

TSPAN18

231

Q96SJ8
MMLIIACIICFTLFF

LHFPL3

116

Q86UP9