Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioninhibitory extracellular ligand-gated monoatomic ion channel activity

GLRA3 GLRA1 GABRA6

8.93e-0681103GO:0005237
GeneOntologyMolecularFunctiongated channel activity

ASIC2 ASIC1 GLRA3 ANO1 CACHD1 GLRA1 CACNA1I CACNA1H VDAC2 GABRA6

1.60e-0533411010GO:0022836
GeneOntologyMolecularFunctionlow voltage-gated calcium channel activity

CACNA1I CACNA1H

8.99e-0531102GO:0008332
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

GLRA3 ANO1 GLRA1 GABRA6

1.65e-04501104GO:0099095
GeneOntologyMolecularFunctionsodium channel activity

ASIC2 ASIC1 CACNA1I CACNA1H

1.93e-04521104GO:0005272
GeneOntologyMolecularFunctionmonoatomic ion channel activity

ASIC2 ASIC1 GLRA3 ANO1 CACHD1 GLRA1 CACNA1I CACNA1H VDAC2 GABRA6

2.26e-0445911010GO:0005216
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GLRA3 ANO1 GLRA1 VDAC2 GABRA6

2.64e-041031105GO:0005253
GeneOntologyMolecularFunctionzinc ion binding

PDE2A CPXM2 ATP13A2 ZRANB3 RNF11 ZFP37 MAP3K1 RNF14 POLR3B DTX4 GLRA1 ADAMTS15 ANKIB1 NOS1

3.84e-0489111014GO:0008270
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

ASIC2 CACNA1I CACNA1H

3.86e-04261103GO:0005248
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC25A18 ASIC2 ASIC1 GLRA3 ANO1 CACHD1 ATP13A2 GLRA1 CACNA1I CACNA1H DMAC2L VDAC2 GABRA6

4.21e-0479311013GO:0015075
GeneOntologyMolecularFunctionextracellularly glycine-gated ion channel activity

GLRA3 GLRA1

4.45e-0461102GO:0016933
GeneOntologyMolecularFunctionextracellularly glycine-gated chloride channel activity

GLRA3 GLRA1

4.45e-0461102GO:0016934
GeneOntologyMolecularFunctionchannel activity

ASIC2 ASIC1 GLRA3 ANO1 CACHD1 GLRA1 CACNA1I CACNA1H VDAC2 GABRA6

6.48e-0452511010GO:0015267
GeneOntologyMolecularFunctionmonoatomic ion-gated channel activity

ASIC2 ASIC1 ANO1

6.53e-04311103GO:0022839
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

ASIC2 ASIC1 GLRA3 ANO1 CACHD1 GLRA1 CACNA1I CACNA1H VDAC2 GABRA6

6.57e-0452611010GO:0022803
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

ASIC2 ASIC1 GLRA3 ANO1 GLRA1 GABRA6

7.03e-041931106GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

ASIC2 ASIC1 GLRA3 ANO1 GLRA1 GABRA6

7.82e-041971106GO:0022834
GeneOntologyMolecularFunctionchloride channel activity

GLRA3 ANO1 GLRA1 GABRA6

1.31e-03861104GO:0005254
GeneOntologyMolecularFunctioncomplement component C1q complex binding

C4A C4B

1.31e-03101102GO:0001849
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

GLRA3 ANO1 GLRA1 VDAC2 GABRA6

1.50e-031511105GO:0008509
GeneOntologyMolecularFunctionclathrin heavy chain binding

LDLR LRP1

1.91e-03121102GO:0032050
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACHD1 CACNA1I CACNA1H

2.08e-03461103GO:0005245
GeneOntologyMolecularFunctionMDM2/MDM4 family protein binding

TP63 TP73

2.25e-03131102GO:0097371
GeneOntologyMolecularFunctionglycine binding

GLRA3 GLRA1

2.62e-03141102GO:0016594
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1I CACNA1H

2.62e-03141102GO:0008331
GeneOntologyBiologicalProcesscell-matrix adhesion

PCSK5 NEXMIF FERMT1 ITGB6 SNED1 PTPRK LRP1 CCN2 EPHA1

1.35e-052701099GO:0007160
GeneOntologyBiologicalProcessregulation of lysosomal protein catabolic process

ATP13A2 LDLR LRP1

3.05e-05121093GO:1905165
GeneOntologyBiologicalProcessregulation of protein catabolic process in the vacuole

ATP13A2 LDLR LRP1

5.01e-05141093GO:1904350
GeneOntologyCellularComponentsomatodendritic compartment

PCSK5 PDE2A BRINP3 ASIC2 NSF ASIC1 GLRA3 ATP13A2 LDLR NELL2 NRSN2 PTPRK TP63 GLRA1 ARHGAP44 LRP1 ASTN2 C4A CACNA1H C4B BSN NOS1 GABRA6

9.99e-08122811123GO:0036477
GeneOntologyCellularComponentdendrite

PCSK5 PDE2A BRINP3 ASIC2 NSF ASIC1 GLRA3 NELL2 PTPRK TP63 GLRA1 ARHGAP44 LRP1 C4A CACNA1H C4B BSN NOS1 GABRA6

1.22e-0785811119GO:0030425
GeneOntologyCellularComponentdendritic tree

PCSK5 PDE2A BRINP3 ASIC2 NSF ASIC1 GLRA3 NELL2 PTPRK TP63 GLRA1 ARHGAP44 LRP1 C4A CACNA1H C4B BSN NOS1 GABRA6

1.26e-0786011119GO:0097447
GeneOntologyCellularComponentneuronal cell body

PCSK5 BRINP3 ASIC2 GLRA3 ATP13A2 NELL2 NRSN2 PTPRK GLRA1 LRP1 ASTN2 C4A CACNA1H C4B BSN GABRA6

8.53e-0683511116GO:0043025
GeneOntologyCellularComponentcell body

PCSK5 BRINP3 ASIC2 GLRA3 ATP13A2 NELL2 NRSN2 PTPRK GLRA1 LRP1 ASTN2 C4A CACNA1H C4B BSN GABRA6

3.16e-0592911116GO:0044297
GeneOntologyCellularComponentpostsynaptic specialization

ASIC2 NSF ASIC1 GLRA3 DAPK1 GLRA1 ARHGAP44 LRP1 BSN NOS1 GABRA6

7.61e-0550311111GO:0099572
GeneOntologyCellularComponentchloride channel complex

GLRA3 ANO1 GLRA1 GABRA6

2.39e-04571114GO:0034707
GeneOntologyCellularComponentsynaptic membrane

PDE2A ASIC2 ASIC1 GLRA3 ANO1 NRP2 GLRA1 LRP1 CACNA1H BSN GABRA6

2.75e-0458311111GO:0097060
GeneOntologyCellularComponentneuron to neuron synapse

ASIC2 NSF ASIC1 DAPK1 C1QL2 ARHGAP44 LRP1 BSN NOS1 GABRA6

4.75e-0452311110GO:0098984
GeneOntologyCellularComponentvesicle tethering complex

VPS11 NBAS VPS41 VPS53

5.87e-04721114GO:0099023
GeneOntologyCellularComponentpostsynaptic specialization membrane

ASIC2 ASIC1 GLRA3 GLRA1 LRP1 GABRA6

7.19e-042011116GO:0099634
GeneOntologyCellularComponentsymbiont cell surface

C4A C4B

7.66e-0481112GO:0106139
GeneOntologyCellularComponentcell surface

ASIC1 PPFIA4 TNFRSF14 ANO1 LDLR ITGB6 IGF2R SEMA6D PTPRK CLEC4A GLRA1 ADAMTS15 LRP1 BSN NOTCH2

7.84e-04111111115GO:0009986
GeneOntologyCellularComponentpresynapse

VPS11 PDE2A ASIC1 PPFIA4 GLRA3 ANO1 GLRA1 ARHGAP44 CACNA1H BSN NOS1 VDAC2 GABRA6

8.45e-0488611113GO:0098793
GeneOntologyCellularComponentmonoatomic ion channel complex

GLRA3 ANO1 CACHD1 GLRA1 CACNA1I CACNA1H DMAC2L GABRA6

9.29e-043781118GO:0034702
GeneOntologyCellularComponentpresynaptic active zone

VPS11 PPFIA4 ARHGAP44 CACNA1H BSN

9.40e-041411115GO:0048786
GeneOntologyCellularComponentother organism part

C4A C4B

9.82e-0491112GO:0044217
GeneOntologyCellularComponentasymmetric synapse

ASIC2 NSF ASIC1 DAPK1 C1QL2 ARHGAP44 LRP1 BSN NOS1

1.01e-034771119GO:0032279
GeneOntologyCellularComponentperikaryon

PCSK5 GLRA3 NELL2 GLRA1 ASTN2 CACNA1H

1.23e-032231116GO:0043204
GeneOntologyCellularComponentpostsynaptic membrane

ASIC2 ASIC1 GLRA3 NRP2 GLRA1 LRP1 CACNA1H GABRA6

1.44e-034051118GO:0045211
GeneOntologyCellularComponentclathrin-coated vesicle

VPS11 LDLR IGF2R VPS41 LRP1 ASTN2

1.68e-032371116GO:0030136
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACHD1 CACNA1I CACNA1H

1.87e-03461113GO:0005891
GeneOntologyCellularComponentAP-3 adaptor complex

VPS11 VPS41

2.10e-03131112GO:0030123
GeneOntologyCellularComponentHOPS complex

VPS11 VPS41

2.44e-03141112GO:0030897
GeneOntologyCellularComponentpostsynaptic density

ASIC2 NSF ASIC1 DAPK1 ARHGAP44 LRP1 BSN NOS1

2.81e-034511118GO:0014069
GeneOntologyCellularComponentpostsynapse

ASIC2 NSF ASIC1 GLRA3 DAPK1 NRP2 GLRA1 ARHGAP44 LRP1 CACNA1H BSN NOS1 GABRA6

2.90e-03101811113GO:0098794
GeneOntologyCellularComponentvoltage-gated sodium channel complex

CACNA1I CACNA1H

3.61e-03171112GO:0001518
GeneOntologyCellularComponentpresynaptic membrane

PDE2A GLRA3 ANO1 GLRA1 CACNA1H GABRA6

3.64e-032771116GO:0042734
GeneOntologyCellularComponentglutamatergic synapse

ASIC1 PPFIA4 ANO1 DAPK1 NRP2 C1QL2 ARHGAP44 LRP1 CACNA1H BSN NOS1

4.13e-0381711111GO:0098978
GeneOntologyCellularComponentearly endosome

VPS11 FGD2 LDLR RNF11 IGF2R VPS41 LRP1 ASTN2

4.15e-034811118GO:0005769
GeneOntologyCellularComponentglycinergic synapse

GLRA3 GLRA1

4.99e-03201112GO:0098690
GeneOntologyCellularComponentleading edge membrane

FGD2 FERMT1 PTPRK ARHGAP44 GABRA6

5.29e-032101115GO:0031256
GeneOntologyCellularComponenthippocampal mossy fiber to CA3 synapse

C1QL2 BSN GABRA6

5.45e-03671113GO:0098686
DomainGrowth_fac_rcpt_

PCSK5 BRINP3 LDLR NELL2 FBN2 MEGF8 LRP1 CCN2 NOTCH2 EPHA1

2.84e-0815611010IPR009030
DomainEGF_2

ZAN LDLR ITGB6 SNED1 NELL2 FBN2 MEGF8 LRP1 ASTN2 NOTCH2 EPHA1

4.70e-0726511011PS01186
DomainEGF

PCSK5 BRINP3 ZAN LDLR SNED1 NELL2 FBN2 MEGF8 LRP1 NOTCH2

1.28e-0623511010SM00181
DomainEGF_Ca-bd_CS

LDLR SNED1 NELL2 FBN2 MEGF8 LRP1 NOTCH2

1.68e-06971107IPR018097
DomainEGF_CA

LDLR SNED1 NELL2 FBN2 MEGF8 LRP1 NOTCH2

1.93e-06991107PS01187
DomainASX_HYDROXYL

LDLR SNED1 NELL2 FBN2 MEGF8 LRP1 NOTCH2

2.07e-061001107PS00010
DomainEGF_1

ZAN LDLR ITGB6 SNED1 NELL2 FBN2 MEGF8 LRP1 ASTN2 NOTCH2

2.67e-0625511010PS00022
DomainEGF-type_Asp/Asn_hydroxyl_site

LDLR SNED1 NELL2 FBN2 MEGF8 LRP1 NOTCH2

3.06e-061061107IPR000152
DomainEGF-like_CS

ZAN LDLR ITGB6 SNED1 NELL2 FBN2 MEGF8 LRP1 NOTCH2 EPHA1

3.29e-0626111010IPR013032
DomainEGF_CA

LDLR SNED1 NELL2 FBN2 MEGF8 LRP1 NOTCH2

7.78e-061221107SM00179
DomainEGF-like_Ca-bd_dom

LDLR SNED1 NELL2 FBN2 MEGF8 LRP1 NOTCH2

8.66e-061241107IPR001881
DomainEGF_3

ZAN LDLR SNED1 NELL2 FBN2 MEGF8 LRP1 ASTN2 NOTCH2

1.05e-052351109PS50026
DomainEGF_CA

LDLR NELL2 FBN2 MEGF8 LRP1 NOTCH2

1.17e-05861106PF07645
DomainEGF-like_dom

PCSK5 ZAN LDLR SNED1 NELL2 FBN2 MEGF8 LRP1 NOTCH2

1.66e-052491109IPR000742
DomainP53

TP63 TP73

1.03e-0431102PF00870
DomainP53

TP63 TP73

1.03e-0431102PS00348
Domainp53_DNA-bd

TP63 TP73

1.03e-0431102IPR011615
Domainp53_tetrameristn

TP63 TP73

1.03e-0431102IPR010991
DomainVDCC_T_a1

CACNA1I CACNA1H

1.03e-0431102IPR005445
Domainp53_tumour_suppressor

TP63 TP73

1.03e-0431102IPR002117
Domain-

TP63 TP73

1.03e-04311024.10.170.10
DomainP53_tetramer

TP63 TP73

1.03e-0431102PF07710
DomainMAM

ZAN NRP2 PTPRK

1.27e-04171103SM00137
DomainMAM

ZAN NRP2 PTPRK

1.52e-04181103PF00629
DomainMAM_dom

ZAN NRP2 PTPRK

1.52e-04181103IPR000998
DomainMAM_2

ZAN NRP2 PTPRK

1.52e-04181103PS50060
DomainROC_dom

DAPK1 LRRK1

2.05e-0441102IPR020859
DomainROC

DAPK1 LRRK1

2.05e-0441102PS51424
DomainGlycine_rcpt_A

GLRA3 GLRA1

2.05e-0441102IPR008127
DomainGalactose-bd-like

PCSK5 CPXM2 NRP2 PTPRK EPHA1

2.34e-04941105IPR008979
DomainGABAA/Glycine_rcpt

GLRA3 GLRA1 GABRA6

3.23e-04231103IPR006028
DomainAnaphylatoxin_comp_syst

C4A C4B

3.40e-0451102IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

3.40e-0451102IPR001840
Domainp53/RUNT-type_TF_DNA-bd

TP63 TP73

5.08e-0461102IPR012346
Domain-

TP63 TP73

5.08e-04611022.60.40.720
DomainhEGF

SNED1 FBN2 NOTCH2

5.85e-04281103PF12661
DomainANATO

C4A C4B

7.08e-0471102SM00104
DomainENaC

ASIC2 ASIC1

7.08e-0471102IPR004724
DomainClathrin

VPS11 VPS41

7.08e-0471102PF00637
DomainANAPHYLATOXIN_2

C4A C4B

7.08e-0471102PS01178
DomainANAPHYLATOXIN_1

C4A C4B

7.08e-0471102PS01177
DomainANATO

C4A C4B

7.08e-0471102PF01821
DomainCHCR

VPS11 VPS41

7.08e-0471102PS50236
DomainAnaphylatoxin/fibulin

C4A C4B

7.08e-0471102IPR000020
Domain-

PCSK5 CPXM2 NRP2 EPHA1

9.07e-047311042.60.120.260
DomainClathrin_H-chain/VPS_repeat

VPS11 VPS41

9.40e-0481102IPR000547
DomainMacrogloblnA2_thiol-ester-bond

C4A C4B

9.40e-0481102IPR019565
DomainThiol-ester_cl

C4A C4B

9.40e-0481102PF10569
DomainMacrogloblnA2_CS

C4A C4B

9.40e-0481102IPR019742
DomainNa+channel_ASC_CS

ASIC2 ASIC1

9.40e-0481102IPR020903
DomainASC

ASIC2 ASIC1

1.20e-0391102PF00858
DomainASC

ASIC2 ASIC1

1.20e-0391102PS01206
DomainNa+channel_ASC

ASIC2 ASIC1

1.20e-0391102IPR001873
DomainPSI_integrin

ITGB6 MEGF8

1.20e-0391102PF17205
DomainIntegin_beta_N

ITGB6 MEGF8

1.20e-0391102IPR033760
DomainVWFC_1

ZAN NELL2 CCN2

1.23e-03361103PS01208
Domain-

VPS11 FGD2 RNF11 MAP3K1 RNF14 DTX4 VPS41 ANKIB1 BSN

1.35e-0344911093.30.40.10
DomainVWFC_2

ZAN NELL2 CCN2

1.44e-03381103PS50184
DomainVWC

ZAN NELL2 CCN2

1.44e-03381103SM00214
DomainA2M

C4A C4B

1.50e-03101102PF00207
DomainA2M_N_2

C4A C4B

1.50e-03101102IPR011625
DomainA2M_comp

C4A C4B

1.50e-03101102IPR011626
DomainA2M_recep

C4A C4B

1.50e-03101102PF07677
DomainA2M_comp

C4A C4B

1.50e-03101102PF07678
DomainA2M_N

C4A C4B

1.50e-03101102PF01835
DomainA2M_N

C4A C4B

1.50e-03101102IPR002890
DomainA-macroglobulin_rcpt-bd

C4A C4B

1.50e-03101102IPR009048
DomainALPHA_2_MACROGLOBULIN

C4A C4B

1.50e-03101102PS00477
DomainE3_UB_ligase_RBR

RNF14 ANKIB1

1.50e-03101102IPR031127
DomainA2M_N_2

C4A C4B

1.50e-03101102PF07703
DomainVDCCAlpha1

CACNA1I CACNA1H

1.50e-03101102IPR002077
DomainMacroglobln_a2

C4A C4B

1.50e-03101102IPR001599
DomainZnf_RING/FYVE/PHD

VPS11 FGD2 RNF11 MAP3K1 RNF14 DTX4 VPS41 ANKIB1 BSN

1.57e-034591109IPR013083
DomainZF_RING_1

VPS11 RNF11 MAP3K1 RNF14 DTX4 VPS41 ANKIB1

1.68e-032911107PS00518
DomainSAM

PPFIA4 TP63 TP73 EPHA1

1.82e-03881104SM00454
DomainMACPF

BRINP3 ASTN2

1.83e-03111102PF01823
DomainZF_RING_2

VPS11 RNF11 MAP3K1 RNF14 DTX4 VPS41 ANKIB1

1.93e-032981107PS50089
DomainVWF_dom

ZAN NELL2 CCN2

1.93e-03421103IPR001007
DomainSAM_2

PPFIA4 TP63 TP73

2.07e-03431103PF07647
DomainMACPF

BRINP3 ASTN2

2.18e-03121102IPR020864
DomainMACPF

BRINP3 ASTN2

2.18e-03121102SM00457
DomainRING

VPS11 RNF11 MAP3K1 RNF14 DTX4 VPS41 ANKIB1

2.19e-033051107SM00184
DomainPSI

ITGB6 SEMA6D MEGF8

2.21e-03441103IPR016201
DomainNeurotransmitter_ion_chnl_CS

GLRA3 GLRA1 GABRA6

2.36e-03451103IPR018000
DomainSAM_DOMAIN

PPFIA4 TP63 TP73 EPHA1

2.40e-03951104PS50105
DomainNeur_chan_memb

GLRA3 GLRA1 GABRA6

2.51e-03461103PF02932
DomainPSI

ITGB6 SEMA6D MEGF8

2.51e-03461103SM00423
DomainSAM

PPFIA4 TP63 TP73 EPHA1

2.59e-03971104IPR001660
DomainNeurotrans-gated_channel_TM

GLRA3 GLRA1 GABRA6

2.67e-03471103IPR006029
Domain-

GLRA3 GLRA1 GABRA6

2.67e-034711032.70.170.10
DomainNeur_chan_LBD

GLRA3 GLRA1 GABRA6

2.67e-03471103PF02931
DomainNEUROTR_ION_CHANNEL

GLRA3 GLRA1 GABRA6

2.67e-03471103PS00236
DomainNeur_channel

GLRA3 GLRA1 GABRA6

2.67e-03471103IPR006201
DomainNeur_chan_lig-bd

GLRA3 GLRA1 GABRA6

2.67e-03471103IPR006202
DomainIBR

RNF14 ANKIB1

2.99e-03141102PF01485
DomainIBR

RNF14 ANKIB1

2.99e-03141102SM00647
DomainLdl_recept_b

LDLR LRP1

2.99e-03141102PF00058
DomainLDLRB

LDLR LRP1

2.99e-03141102PS51120
DomainZnf_RING

VPS11 RNF11 MAP3K1 RNF14 DTX4 VPS41 ANKIB1

3.18e-033261107IPR001841
DomainLY

LDLR LRP1

3.43e-03151102SM00135
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

FASTKD5 MCM7 CACHD1 PHGDH FBN2 IGF2R NUP155 MEGF8 LRP1 TMEM131L ITPRIP VDAC2

7.92e-076131131222268729
Pubmed

Integral and associated lysosomal membrane proteins.

DAGLB VPS11 NSF ATP13A2 VPS41 LRP1

3.69e-06126113617897319
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

1.05e-052113222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

1.05e-052113216565498
Pubmed

Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis.

ASIC2 ASIC1

1.05e-052113221307247
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

1.05e-052113215998580
Pubmed

Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli.

ASIC2 ASIC1

1.05e-052113224256442
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

1.05e-052113219062096
Pubmed

Characterization of the glycinergic input to bipolar cells of the mouse retina.

GLRA3 GLRA1

1.05e-052113216420443
Pubmed

Acid-sensing ion channel-1b in the stereocilia of mammalian cochlear hair cells.

ASIC2 ASIC1

1.05e-052113216951561
Pubmed

Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice.

ASIC2 ASIC1

1.05e-052113227820848
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

1.05e-052113219933335
Pubmed

A T-type calcium channel required for normal function of a mammalian mechanoreceptor.

CACNA1I CACNA1H

1.05e-052113212808460
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

1.05e-05211322459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

1.05e-052113217645767
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

1.05e-052113212207352
Pubmed

Low density lipoprotein receptor-related protein polymorphisms are not risk factors for venous thromboembolism.

LDLR LRP1

1.05e-052113217889283
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

1.05e-052113227758680
Pubmed

The protein levels of MCM7 and p63 in evaluating lesion severity of cervical disease.

MCM7 TP63

1.05e-052113223318911
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

1.05e-052113222387014
Pubmed

Tumor-specific p73 up-regulation mediates p63 dependence in squamous cell carcinoma.

TP63 TP73

1.05e-052113217018588
Pubmed

Rebound burst firing in the reticular thalamus is not essential for pharmacological absence seizures in mice.

CACNA1I CACNA1H

1.05e-052113225071191
Pubmed

BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels.

ASIC2 ASIC1

1.05e-05211329037075
Pubmed

Phosphorylation of α3 glycine receptors induces a conformational change in the glycine-binding site.

GLRA3 GLRA1

1.05e-052113223834509
Pubmed

Upregulation of acid-sensing ion channel 1 protein expression by chronic administration of cocaine in the mouse striatum in vivo.

ASIC2 ASIC1

1.05e-052113219427358
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

1.05e-052113223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

1.05e-052113223918728
Pubmed

Conformational stability and activity of p73 require a second helix in the tetramerization domain.

TP63 TP73

1.05e-052113219763140
Pubmed

Upregulation of hepatic LDL transport by n-3 fatty acids in LDL receptor knockout mice.

LDLR LRP1

1.05e-052113211971949
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

1.05e-05211323037333
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

1.05e-052113211726230
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

1.05e-05211324216347
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

1.05e-05211326950384
Pubmed

Whole Exome Sequencing of Hemiplegic Migraine Patients Shows an Increased Burden of Missense Variants in CACNA1H and CACNA1I Genes.

CACNA1I CACNA1H

1.05e-052113236786913
Pubmed

p73 and p63 regulate the expression of fibroblast growth factor receptor 3.

TP63 TP73

1.05e-052113220298673
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

1.05e-05211328660986
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

1.05e-05211328428773
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

1.05e-052113224638111
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

1.05e-052113221345967
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

1.05e-05211322572548
Pubmed

The complement component C4 of mammals.

C4A C4B

1.05e-05211322302180
Pubmed

Differential localization of Acid-sensing ion channels 1 and 2 in human cutaneus pacinian corpuscles.

ASIC2 ASIC1

1.05e-052113220306292
Pubmed

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.

C4A C4B

1.05e-052113222151770
Pubmed

C4d-positive chronic rejection: a frequent entity with a poor outcome.

C4A C4B

1.05e-052113218091514
Pubmed

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

C4A C4B

1.05e-052113229080553
Pubmed

LRP: role in vascular wall integrity and protection from atherosclerosis.

LDLR LRP1

1.05e-052113212690199
Pubmed

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.

C4A C4B

1.05e-05211326589636
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

1.05e-052113225339671
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

1.05e-052113217728371
Pubmed

Presynaptic release probability is increased in hippocampal neurons from ASIC1 knockout mice.

ASIC2 ASIC1

1.05e-052113218094106
Pubmed

Structure and organization of the C4 genes.

C4A C4B

1.05e-05211326149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

1.05e-05211326149581
Pubmed

ASIC subunit ratio and differential surface trafficking in the brain.

ASIC2 ASIC1

1.05e-052113226746198
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

1.05e-052113212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

1.05e-05211323542363
Pubmed

Acid-sensing ion channels (ASICs) are differentially modulated by anions dependent on their subunit composition.

ASIC2 ASIC1

1.05e-052113223135698
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

1.05e-05211322387317
Pubmed

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.

C4A C4B

1.05e-052113216908004
Pubmed

Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.

C4A C4B

1.05e-05211327365238
Pubmed

p63 and p73 do not contribute to p53-mediated lymphoma suppressor activity in vivo.

TP63 TP73

1.05e-052113216007185
Pubmed

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

C4A C4B

1.05e-05211327391573
Pubmed

Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.

C4A C4B

1.05e-052113217971360
Pubmed

Low density lipoprotein receptor-related protein (LRP) is a heparin-dependent adhesion receptor for connective tissue growth factor (CTGF) in rat activated hepatic stellate cells.

LRP1 CCN2

1.05e-052113214585398
Pubmed

Clinical features of patients with homozygous complement C4A or C4B deficiency.

C4A C4B

1.05e-052113229928053
Pubmed

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.

C4A C4B

1.05e-052113217971229
Pubmed

Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.

C4A C4B

1.05e-05211326881182
Pubmed

The Role of p63 and p73 in tumor formation and progression: coming of age toward clinical usefulness. Commentary re: F. Koga et al., Impaired p63 expression associates with poor prognosis and uroplakin III expression in invasive urothelial carcinoma of the bladder. Clin. Cancer Res., 9: 5501-5507, 2003, and P. Puig et al., p73 Expression in human normal and tumor tissues: loss of p73alpha expression is associated with tumor progression in bladder Cancer. Clin. Cancer Res., 9: 5642-5651, 2003.

TP63 TP73

1.05e-052113214654522
Pubmed

Partial C4 deficiency in juvenile idiopathic arthritis patients.

C4A C4B

1.05e-052113217921792
Pubmed

Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.

C4A C4B

1.05e-052113221880985
Pubmed

Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.

C4A C4B

1.05e-05211326978711
Pubmed

Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.

C4A C4B

1.05e-052113235898513
Pubmed

Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.

C4A C4B

1.05e-052113228873507
Pubmed

The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers.

TP63 TP73

1.05e-052113217446929
Pubmed

Multifunctional basic motif in the glycine receptor intracellular domain induces subunit-specific sorting.

GLRA3 GLRA1

1.05e-052113219959465
Pubmed

Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.

C4A C4B

1.05e-0521132276882
Pubmed

Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.

C4A C4B

1.05e-05211326832377
Pubmed

Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.

C4A C4B

1.05e-05211323794341
Pubmed

Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants.

LDLR LRP1

1.05e-05211329449704
Pubmed

Changes in H+, K+, and Ca2+ Concentrations, as Observed in Seizures, Induce Action Potential Signaling in Cortical Neurons by a Mechanism That Depends Partially on Acid-Sensing Ion Channels.

ASIC2 ASIC1

1.05e-052113234720879
Pubmed

Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.

C4A C4B

1.05e-052113222785613
Pubmed

Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.

C4A C4B

1.05e-052113232691186
Pubmed

The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.

C4A C4B

1.05e-05211328390682
Pubmed

Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).

C4A C4B

1.05e-05211323902619
Pubmed

Structural polymorphism of murine C4 and its linkage to H-2.

C4A C4B

1.05e-05211327373044
Pubmed

The chemical structure of the C4d fragment of the human complement component C4.

C4A C4B

1.05e-05211323696167
Pubmed

Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.

C4A C4B

1.05e-05211321357031
Pubmed

Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.

C4A C4B

1.05e-052113216098595
Pubmed

LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome.

LDLR LRP1

1.05e-052113217505534
Pubmed

Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.

C4A C4B

1.05e-052113215787745
Pubmed

p63 and p73 expression in extrahepatic bile duct carcinoma and their clinical significance.

TP63 TP73

1.05e-052113217385050
Pubmed

Death-associated protein kinase-mediated cell death modulated by interaction with DANGER.

DAPK1 ITPRIP

1.05e-052113220053891
Pubmed

p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis.

TP63 TP73

1.05e-052113216413471
Pubmed

Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala.

ASIC2 ASIC1

1.05e-052113224889629
Pubmed

Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.

C4A C4B

1.05e-052113230026462
Pubmed

The role of p53 protein family in gastrointestinal malignancies.

TP63 TP73

1.05e-052113216557273
Pubmed

A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.

C4A C4B

1.05e-05211326559257
Pubmed

Probing glycine receptor stoichiometry in superficial dorsal horn neurones using the spasmodic mouse.

GLRA3 GLRA1

1.05e-052113221486794
Pubmed

Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.

C4A C4B

1.05e-052113234299197
Pubmed

Assessment of complement C4 gene copy number using the paralog ratio test.

C4A C4B

1.05e-052113220506482
Pubmed

Diagnostic role of DOG1 and p63 immunohistochemistry in salivary gland carcinomas.

ANO1 TP63

1.05e-052113226464669
InteractionFBXO2 interactions

PCSK5 CACHD1 SNED1 NELL2 FBN2 IGF2R MEGF8 PTPRK TMEM131L NOTCH2 EPHA1

1.30e-0541110811int:FBXO2
InteractionZFP41 interactions

LDLR NELL2 FBN2 LRP1 NOTCH2

1.35e-05571085int:ZFP41
GeneFamilyAcid sensing ion channel subunits

ASIC2 ASIC1

1.78e-045772290
GeneFamilyGlycine receptors

GLRA3 GLRA1

1.78e-045772868
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

6.32e-0497721234
GeneFamilyLow density lipoprotein receptors

LDLR LRP1

1.35e-0313772634
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ASIC2 ASIC1 LDLR XYLT1 C1QL2 LRP1 NOS1 UNC79

4.08e-08199112819a97e27a4758e794ce7246d295e112b47931a48
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 ITGB6 MAP3K1 SLPI VPS41 ADAMTS15 ASTN2

4.63e-0718611273dae539cce15fcf2b1b32e981d7febe94c03c600
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 THSD7B NRP2 C1QL2 FBN2 SEMA6D NOS1

4.98e-0718811278268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 ASIC2 ASIC1 XYLT1 C1QL2 NELL2 LRP1

4.98e-071881127a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 ASIC2 ASIC1 XYLT1 C1QL2 NELL2 LRP1

4.98e-071881127c8530c9ff98666c64a94683261af4288cb790a7e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 NEXMIF DAPK1 ITGB6 SEMA6D ASTN2 NOS1

5.16e-071891127e059be2965cca70ff5576df055d0af1775b76e00
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 THSD7B NRP2 C1QL2 FBN2 SEMA6D NOS1

5.34e-07190112759720dfe9de1b980807644536c919d2a02ba69dd
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 ASIC2 ASIC1 XYLT1 C1QL2 NELL2 LRP1

5.34e-0719011279b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 ASIC2 ASIC1 XYLT1 C1QL2 NELL2 LRP1

5.34e-071901127d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ASIC2 ASIC1 LDLR XYLT1 C1QL2 LRP1 NOS1

7.29e-071991127333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ASIC2 ASIC1 LDLR XYLT1 C1QL2 LRP1 NOS1

7.29e-071991127e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGD2 MCM7 PHGDH GLRA1 CACNA1I NOS1

2.22e-061501126cc8361bdcaa16ab6a0d6a3684690d709bc42ff3b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 SLPI ABCC12 ANKRD12 UNC79 GABRA6

5.40e-06175112665571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 ITGB6 MAP3K1 VPS41 ADAMTS15 ASTN2

6.56e-0618111266a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLRA3 LRRK1 XYLT1 SNED1 NELL2 PTPRK

6.77e-06182112614a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISX ITGB6 TP63 ANKIB1 SPDYA EPHA1

6.77e-0618211269174fb0b7ed8f721a5c513e41fd80476a9f34332
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

CLDN18 CACHD1 LDLR ITGB6 PTPRK SLPI

6.98e-0618311268e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 ITGB6 MAP3K1 VPS41 ADAMTS15 ASTN2

6.98e-061831126cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 ITGB6 MAP3K1 FBN2 ADAMTS15 ASTN2

6.98e-06183112692fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 NEXMIF DAPK1 ITGB6 ASTN2 NOS1

7.20e-061841126d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDE2A THSD7B SEMA6D STARD9 CACNA1H CCN2

7.90e-061871126fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 ITGB6 MAP3K1 SLPI ADAMTS15 ASTN2

8.39e-0618911261ecf9911ff82e0ca0f0c101b735d3b1f3b339d57
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 NRP2 C1QL2 FBN2 SEMA6D NOS1

8.39e-061891126222e67d3fd106c43b0cae6538dddeaa7be1f759f
ToppCellfacs-Skin-Anagen|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BICD2 ATP13A2 ITGB6 RNF11 MAP3K1 EPHA1

8.39e-061891126adbfc723130079b4caf551f66d2aee86fab1903c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CLDN18 DAPK1 CACHD1 ITGB6 PTPRK ARHGAP44

8.65e-0619011268aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 ANO1 SNED1 LRP1 ASTN2 NOTCH2

8.91e-06191112614057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FASTKD5 NUP155 SLPI VPS41 ANKIB1 CCN2

8.91e-06191112639ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CLDN18 DAPK1 CACHD1 ITGB6 PTPRK ARHGAP44

8.91e-061911126ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

CLDN18 DAPK1 CACHD1 ITGB6 PTPRK ARHGAP44

8.91e-061911126d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellE17.5-Epithelial-epithelial_progenitor_cell-epi_progenitor|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CLDN18 NEXMIF FERMT1 MCM7 PHGDH FBN2

8.91e-061911126328b98d371a7d6b6a1adc61ded05a3e52a839894
ToppCellChildren_(3_yrs)-Immune-monocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FGD2 LRRK1 MAP3K1 XYLT1 FBN2 NOTCH2

9.46e-06193112658e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

CLDN18 NEXMIF ANO1 ITGB6 PHGDH ARHGAP44

9.46e-061931126c1817ad675b9f9d2d3436c8b9646edf89f0d4c82
ToppCellE16.5-samps-Epithelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

CLDN18 NEXMIF ANO1 ITGB6 PHGDH ARHGAP44

9.46e-0619311261cb5a1cffa2b4a3bfecca16b791c1992edeb237d
ToppCellControl-Epithelial|Control / Disease state, Lineage and Cell class

CLDN18 CACHD1 ITGB6 PTPRK ARHGAP44 SLPI

1.00e-0519511261798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCelldroplet-Tongue-TONGUE|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPXM2 ARHGAP5 ITPRIP ANKRD12 GPAT2 EPHA1

1.03e-05196112644a30b1a5f3d8c845e5f3bd17d8102a7449f555b
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

NEXMIF DAPK1 ITGB6 SEMA6D CACNA1H NOS1

1.03e-05196112604f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCelldroplet-Tongue-TONGUE-1m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPXM2 ARHGAP5 ITPRIP ANKRD12 GPAT2 EPHA1

1.03e-0519611269935bdb10789e8cfc922dca526ca3bf8317fe270
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

PDE2A THSD7B NRP2 SNED1 ITPRIP CCN2

1.03e-051961126e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPXM2 ARHGAP5 ITPRIP ANKRD12 GPAT2 EPHA1

1.03e-051961126a85f5f1e6acc798e9e02b1a21e0ffe87a323c333
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK5 FERMT1 CACHD1 ITGB6 TP63 TP73

1.09e-0519811265374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DAPK1 CACHD1 LDLR ITGB6 PTPRK ARHGAP44

1.13e-0519911265f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BICD2 PCSK5 FERMT1 CACHD1 TP63 TP73

1.13e-05199112694a7867e800df352731796de8c24cba133c29622
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DAPK1 CACHD1 LDLR ITGB6 PTPRK ARHGAP44

1.13e-0519911265cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ASIC1 LDLR XYLT1 C1QL2 LRP1 NOS1

1.16e-052001126ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

ANO1 PHGDH FBN2 SEMA6D LRP1 NOTCH2

1.16e-052001126bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 THSD7B NRP2 FBN2 GLRA1

4.13e-05152112588a810d41edb5a917c23cb5ba5a387227e1312cb
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PCSK5 ASIC2 ANO1 SNED1 SEMA6D

4.82e-051571125b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellStriatum-Neuronal-Inhibitory|Striatum / BrainAtlas - Mouse McCarroll V32

RNF11 GLRA1 DLEU7 ASTN2 NOS1

4.82e-051571125c41ff3fe9de7187575114febfe9bd8733366fb8a
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLDN18 ANO1 ITGB6 FBN2 TP63

5.59e-05162112534b4cd3d2258f88dfbd6d32abd1db87aff8a6b6f
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLDN18 ANO1 ITGB6 FBN2 TP63

5.76e-05163112556b8668dbf06faa6866ec71f29b92907b73f074d
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Gad1Gad2-Th.Trh_(Th+_interneuron)|Striatum / BrainAtlas - Mouse McCarroll V32

C16orf96 XYLT1 GLRA1 EPHA1

6.31e-0585112467336aa7ec02b64595ce7d5222d43cead92eb52e
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th|Striatum / BrainAtlas - Mouse McCarroll V32

C16orf96 XYLT1 GLRA1 EPHA1

6.31e-05851124a7a5d82924cd4a41ab87b1abf13143635882a4b2
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Gad1Gad2-Th.Trh_(Th+_interneuron)-|Striatum / BrainAtlas - Mouse McCarroll V32

C16orf96 XYLT1 GLRA1 EPHA1

6.31e-0585112486c5d71b66ff55c44d2d457865dda72e07e5ec53
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ASIC1 FBN2 DLEU7 ASTN2 CCN2

6.46e-05167112555c3c68af269fcf40f2b080ae4489523609ad388
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FERMT1 ANO1 GCKR NOTCH2 TP73

6.65e-051681125100ab6d36592b61f4db9f8cb90c48afac016d679
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 GLRA3 LRRK1 SEMA6D PTPRK

6.83e-051691125319cba07263bf41fcbcbfecd117f91b729394241
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 ZAN C4B UNC79 TP73

6.83e-05169112512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

DAPK1 CACHD1 ITGB6 NRP2 PTPRK

7.03e-051701125269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 GLRA3 LRRK1 SEMA6D PTPRK

7.03e-051701125985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Uncommitted_AE_cell|E16.5-samps / Age Group, Lineage, Cell class and subclass

CLDN18 FERMT1 ANO1 PHGDH ARHGAP44

7.03e-0517011255a64e05c263df915085988d881808221e2c0f2e2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIA4 ANO1 ZFP37 TMEM131L GPAT2

7.03e-05170112599dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIA4 ANO1 ZFP37 TMEM131L GPAT2

7.03e-0517011253a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIA4 ANO1 ZFP37 TMEM131L GPAT2

7.03e-051701125cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 ISX ARHGAP5 LRP1 ANKIB1

7.63e-051731125e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCellfacs-Large_Intestine-Proximal-3m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 ISX ARHGAP5 LRP1 ANKIB1

7.63e-05173112599532bb768ee35fed939a377acb5215d3f8904bd
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 GLRA3 LRRK1 SEMA6D PTPRK

7.63e-0517311259a2d42f8d9cb834856522661d524abb91c4637c5
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A ASIC2 NRP2 DLEU7 BSN

8.06e-0517511259d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A ASIC2 NRP2 DLEU7 BSN

8.06e-051751125f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 MAP3K1 FBN2 VPS41 ASTN2

8.06e-051751125284fdc7a9d303636a637041846850d19d114861a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 ASIC1 XYLT1 C1QL2 SPDYA

8.28e-051761125ef0ff02897104e938c8a632357d8f1a6f014e68a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BRINP3 ASIC1 GLRA1 CACNA1H NOS1

8.28e-05176112505ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 ASIC1 XYLT1 C1QL2 SPDYA

8.28e-051761125da0983929fa682a68e536c298a2d7add188b7563
ToppCellHippocampus|World / BrainAtlas - Mouse McCarroll V32

THSD7B NRP2 C1QL2 NELL2 NOS1

8.28e-051761125f120a703f6d2f2d5f55eae1aea2e6382a485828f
ToppCellfacs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPXM2 ANO1 NELL2 ARHGAP44 CACNA1H

8.50e-05177112532fecefba1a55e1f418c9a055236fa11175c692d
ToppCellfacs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPXM2 ANO1 NELL2 ARHGAP44 CACNA1H

8.50e-0517711251b153fbfe1323dc589de4af73a52149ea5ce6763
ToppCellControl-Epithelial_alveolar-AT_1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLDN18 DAPK1 ITGB6 PRSS36 ARHGAP44

8.73e-051781125aa7d43c655df493f1330a5001efaa484e4a19f69
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DAGLB PRSS54 FGD2 PRSS36 KIF25-AS1

8.73e-05178112524e8c62060455159235985f456af0c5023a7f3f5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DAGLB PRSS54 FGD2 PRSS36 KIF25-AS1

8.73e-0517811254f1cc954d4d9b5b2b75a4cf995ba81e2ada27084
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 GLRA3 LRRK1 SEMA6D PTPRK

8.96e-0517911258766a5a066091879f521acfc612abf563ff78808
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN18 ANO1 ITGB6 ARHGAP44 GPAT2

8.96e-05179112588dbec952507d84b85b08165eec80df99ed1e736
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN18 ANO1 ITGB6 ARHGAP44 GPAT2

8.96e-051791125daf8189a22786171e2b629261cf720736aa4ebdb
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CLDN18 DAPK1 ITGB6 PTPRK ARHGAP44

8.96e-051791125cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEXMIF ANO1 C4B CCN2 EPHA1

8.96e-051791125e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 ASIC1 XYLT1 C1QL2 LRP1

9.20e-051801125fa819df81fca95c2cc602fede635cb03e3f35fad
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 ASIC1 XYLT1 C1QL2 LRP1

9.20e-051801125907cd510fd2e21532ce04ba687e8894f7af71f27
ToppCellfacs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE2A ASIC2 NRP2 DLEU7 BSN

9.44e-051811125b0fff0defba9aea6fba36e378b05a59986e2573a
ToppCellCOPD-Epithelial-Basal|World / Disease state, Lineage and Cell class

FERMT1 CACHD1 ITGB6 PTPRK TP63

9.44e-0518111256d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCellfacs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE2A ASIC2 NRP2 DLEU7 BSN

9.44e-051811125cc77ac0e223e012767222e45c5dcadc246d1aa7c
ToppCellfacs-Lung-18m-Endothelial-lymphatic_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE2A ASIC2 NRP2 DLEU7 BSN

9.44e-051811125ecd52f33841f4e9d946a4edad0d58da9b0cc5ffa
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN18 FGD2 FBP1 SLPI BSN

9.69e-05182112581c394959414173016426961478f670cd822f8b3
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN18 FGD2 FBP1 SLPI BSN

9.69e-05182112541a7543c8b703441ff6ac2307faffe5f798b2c41
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGB6 SNED1 SEMA6D ASTN2 NOS1

9.69e-051821125a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellControl-Epithelial-Basal|Control / Disease state, Lineage and Cell class

CACHD1 PTPRK TP63 SLPI CCN2

9.69e-051821125caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 NRP2 FBN2 NOS1 NOTCH2

9.94e-051831125f8b636391f752e379a5c5575fd898bdf0907a3b8
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

FERMT1 CACHD1 ITGB6 PTPRK TP63

9.94e-0518311250f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 THSD7B FBN2 NOS1 NOTCH2

1.02e-041841125e2de27cee3ea80f9b7a9a7884ceceeaa67b3214a
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

CACHD1 LDLR ITGB6 PTPRK ARHGAP44

1.02e-041841125369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 CACHD1 ARHGAP44 CCN2 TP73

1.02e-041841125f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 CACHD1 ARHGAP44 CCN2 TP73

1.02e-0418411258bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 ASIC1 XYLT1 C1QL2 LRP1

1.02e-041841125278a7ed764c326450cb70e69ed2175980eaf5fe0
ComputationalNeurotransmitter (GABA) receptor.

GLRA3 GLRA1 GABRA6

8.70e-0515643MODULE_215
Diseasebody weight

PCSK5 BRINP3 ZBTB38 HIVEP2 NEXMIF WDR70 ANO1 GCKR THSD7B NBAS FBN2 SEMA6D GLRA1 DLEU7 ASTN2 UNC79

1.79e-05126111016EFO_0004338
Diseaseneuropilin-2 measurement

NRP2 NELL2

4.12e-0531102EFO_0801836
Diseaseneuropathy, type 2 diabetes mellitus

NRP2 NELL2

4.12e-0531102EFO_0004149, MONDO_0005148
DiseaseGingival bleeding

ASIC2 PHGDH

8.22e-0541102HP_0000225
Diseasetesticular cancer (implicated_via_orthology)

TP63 TP73

1.37e-0451102DOID:2998 (implicated_via_orthology)
Diseasequality of life during menstruation measurement

ASIC2 ASTN2

1.37e-0451102EFO_0009366
DiseaseGlobal developmental delay

NSF INTS1 NBAS GLRA1 VPS53

1.45e-041331105C0557874
Diseasetemporal lobe epilepsy (biomarker_via_orthology)

NSF NOS1 VDAC2

2.10e-04311103DOID:3328 (biomarker_via_orthology)
DiseaseCrohn's disease

ZBTB38 PSMA6 FERMT1 C16orf96 GCKR PTPRK BSN NOTCH2

2.53e-044411108EFO_0000384
DiseaseCommon Migraine

LRP1 ASTN2

2.86e-0471102C0338480
DiseaseParkinson Disease

ATP13A2 IGF2R FBP1 NOS1

2.93e-04851104C0030567
Diseasecholelithiasis

DAGLB ZNF438 ANO1 GCKR

3.35e-04881104EFO_0004799
DiseaseDevelopmental delay (disorder)

NBAS GLRA1 VPS53

3.57e-04371103C0424605
Diseasetriacylglycerol 50:3 measurement

NEXMIF GCKR VPS53

4.18e-04391103EFO_0010410
Diseasemultiple system atrophy

THSD7B FBN2 ARHGAP44

4.50e-04401103EFO_1001050
Diseasecolonic neoplasm

FGD2 ASTN2 ABCC12

4.85e-04411103EFO_0004288
Diseasesciatic neuropathy (biomarker_via_orthology)

PCSK5 LRP1 CACNA1I CACNA1H

5.24e-04991104DOID:11446 (biomarker_via_orthology)
Diseaseinterleukin 9 measurement

NRP2 NELL2 DLEU7

5.58e-04431103EFO_0008192
Diseasesubiculum volume

NSF SEMA6D ASTN2

5.58e-04431103EFO_0009399
Diseasetriglycerides in large LDL measurement

GCKR LDLR IGF2R

5.58e-04431103EFO_0022319
Diseaseglucose measurement

ZBTB38 ZAN LRRC37A3 GCKR MEGF8 CACNA1I BSN

5.68e-043801107EFO_0004468
Diseaselinoleic acid measurement

FGD2 GCKR THSD7B LDLR IGF2R

6.76e-041861105EFO_0006807
Diseasebody surface area

PCSK5 PDE2A ZBTB38 GCKR ATP13A2 FBN2 DLEU7 ASTN2 UNC79

6.90e-046431109EFO_0022196
Diseasephospholipids in medium LDL measurement

GCKR LDLR IGF2R

8.20e-04491103EFO_0022183
Diseasecerebral white matter volume change measurement

ASIC2 LINC00303

8.87e-04121102EFO_0021499
Diseasetotal lipids in LDL measurement

GCKR LDLR IGF2R

9.75e-04521103EFO_0022308
Diseaseintelligence, self reported educational attainment

FAM193A SEMA6D CACNA1I BSN

9.81e-041171104EFO_0004337, EFO_0004784
Diseasecardiomyopathy (biomarker_via_orthology)

PDE2A NOS1

1.05e-03131102DOID:0050700 (biomarker_via_orthology)
DiseaseCongenital pontocerebellar hypoplasia

EXOSC3 VPS53

1.05e-03131102C0266468
Diseasetotal lipids in medium VLDL

GCKR LDLR IGF2R

1.09e-03541103EFO_0022153
Diseaseasthma, Eczema, allergic rhinitis

ZBTB38 PSMA6 TNFRSF14 PTPRK

1.11e-031211104EFO_0005854, HP_0000964, MONDO_0004979
Diseasetriglycerides in LDL measurement

GCKR LDLR IGF2R

1.21e-03561103EFO_0022320
Diseasenephroblastoma (is_implicated_in)

IGF2R TP73

1.22e-03141102DOID:2154 (is_implicated_in)
Diseasetotal lipids in large LDL

GCKR LDLR IGF2R

1.27e-03571103EFO_0022163
Diseasecholesterol in large LDL measurement

GCKR LDLR IGF2R

1.27e-03571103EFO_0021901
Diseasesmoking status measurement

ZNF438 CPXM2 ASIC2 NSF THSD7B XYLT1 SEMA6D PTPRK ITPRIP UNC79 VDAC2 GABRA6

1.31e-03116011012EFO_0006527
Diseasetriglycerides in IDL measurement

GCKR LDLR IGF2R

1.34e-03581103EFO_0022149
DiseaseYKL40 measurement

PPFIA4 GCKR

1.40e-03151102EFO_0004869
Diseasephospholipids in VLDL measurement

GCKR LDLR IGF2R

1.41e-03591103EFO_0022301
Diseasephospholipids in small LDL measurement

GCKR LDLR IGF2R

1.41e-03591103EFO_0022297
Diseasetotal lipids in VLDL measurement

GCKR LDLR IGF2R

1.48e-03601103EFO_0022314
Diseaseinflammatory bowel disease

PCSK5 FERMT1 TNFRSF14 GCKR SEMA6D PTPRK BSN

1.49e-034491107EFO_0003767
Diseasetotal blood protein measurement

ZNF438 ZBTB38 GCKR LRRK1 TP63 DLEU7 TMEM131L

1.49e-034491107EFO_0004536
Diseasefree cholesterol in VLDL measurement

GCKR LDLR IGF2R

1.55e-03611103EFO_0022276
Diseaseresponse to antineoplastic agent, response to antimicrotubule agent

ARHGAP44 TMEM131L

1.60e-03161102EFO_0005260, GO_0097327
Diseasecoffee consumption, cups of coffee per day measurement

GCKR VDAC2

1.60e-03161102EFO_0004330, EFO_0006782
DiseasePontoneocerebellar hypoplasia

EXOSC3 VPS53

1.60e-03161102cv:C1261175
Diseasemigraine without aura, susceptibility to, 4

LRP1 ASTN2

1.60e-03161102MONDO_0011847
Diseasetriglycerides in medium LDL measurement

GCKR LDLR IGF2R

1.62e-03621103EFO_0022322
Diseasecholesterol in large VLDL measurement

GCKR LDLR IGF2R

1.86e-03651103EFO_0021902
Diseasecholesterol in very large VLDL measurement

GCKR LDLR IGF2R

1.86e-03651103EFO_0022230
Diseasetotal lipids in small VLDL

GCKR LDLR IGF2R

2.03e-03671103EFO_0022148
DiseaseFEV/FEC ratio

ZNF438 PCSK5 CLDN18 HIVEP2 ANO1 MCM7 ATP13A2 MAP3K1 NRP2 NELL2 LRP1 ASTN2

2.11e-03122811012EFO_0004713
DiseaseAbdominal Aortic Aneurysm

FERMT1 LDLR LRP1

2.12e-03681103EFO_0004214
Diseaserenal cell carcinoma (is_implicated_in)

C4A C4B TP73

2.21e-03691103DOID:4450 (is_implicated_in)
DiseaseCongenital hernia of foramen of Morgagni

IGF2R CCN2

2.26e-03191102C0265699
DiseaseCongenital hernia of foramen of Bochdalek

IGF2R CCN2

2.26e-03191102C0265700
Diseaseresponse to supplemental oxygen

ASIC2 ASTN2

2.26e-03191102EFO_0009796
Diseasehemorrhoid

BICD2 ANO1 ITGB6 ASTN2

2.27e-031471104EFO_0009552
Diseaseserum non-albumin protein measurement

ZBTB38 WBP2NL LRRK1 PRSS36 TP63 TMEM131L

2.37e-033611106EFO_0004568
Diseaseblood aluminium measurement

ZBTB38 DAPK1

2.50e-03201102EFO_0007575
Diseasemajor depressive disorder

HIVEP2 SEMA6D ASTN2 BSN

2.75e-031551104MONDO_0002009
DiseaseCongenital diaphragmatic hernia

IGF2R CCN2

2.76e-03211102C0235833
DiseaseAntimigraine preparation use measurement

LRP1 ASTN2

2.76e-03211102EFO_0009939
DiseaseParkinson's disease (implicated_via_orthology)

NSF LRRK1 ATP13A2 VPS41

2.88e-031571104DOID:14330 (implicated_via_orthology)
DiseaseAutistic Disorder

ASIC2 NRP2 ASTN2 CACNA1H C4B

3.00e-032611105C0004352
Diseasetriacylglycerol 48:2 measurement

GCKR VPS53

3.03e-03221102EFO_0010405
Diseasetriacylglycerol 54:6 measurement

GCKR C1QL2

3.03e-03221102EFO_0010424
DiseaseLung diseases

PCSK5 IGF2R CCN2

3.13e-03781103C0024115
DiseaseLung Neoplasms

DAPK1 TP63 CCN2 NOTCH2 TP73

3.20e-032651105C0024121
DiseaseMalignant neoplasm of lung

DAPK1 TP63 CCN2 NOTCH2 TP73

3.25e-032661105C0242379
Diseaseepilepsy (implicated_via_orthology)

NSF LRP1 BSN NOS1

3.29e-031631104DOID:1826 (implicated_via_orthology)
DiseaseImmunologic Deficiency Syndromes

NBAS C4A

3.31e-03231102C0021051
Diseaseclinical and behavioural ideal cardiovascular health

BRINP3 LDLR

3.31e-03231102EFO_0007654
Diseaseinsulin sensitivity measurement

GCKR PHGDH

3.31e-03231102EFO_0004471
Diseasecomplex trait

ZBTB38 ZAN GCKR LDLR NBAS

3.52e-032711105EFO_0010578
DiseaseHodgkins lymphoma

DDX12P PTPRK CACNA1I

3.60e-03821103EFO_0000183
Diseaseeosinophil count

HIVEP2 FERMT1 TNFRSF14 ANO1 WBP2NL C16orf96 CACHD1 GCKR ITGB6 FAM193A CACNA1H NOTCH2 VDAC2

3.63e-03148811013EFO_0004842
Diseasediastolic blood pressure, systolic blood pressure

PSMA6 GLRA3 ANO1 C16orf96 XYLT1 ADAMTS15 LRP1 GABRA6

3.66e-036701108EFO_0006335, EFO_0006336

Protein segments in the cluster

PeptideGeneStartEntry
RMDMDTPHCLTCPQQ

EPHA1

286

P21709
PGCENVSVRSRSMMF

DAPK1

751

P53355
FPECNCPSMDIQAME

BRINP3

286

Q76B58
VCMCNNETPNRVMLD

BICD2

541

Q8TD16
CESMERSCPGNYPMQ

LINC00303

101

Q3SY05
RCCQDGVTRLPMMRS

C4B

701

P0C0L5
MDMNPECFVSPRCAK

FERMT1

511

Q9BQL6
QDCCTIPPSMMEFDG

CACHD1

126

Q5VU97
CMCSISVFEDPVDMP

ANKIB1

336

Q9P2G1
SRCDSDLCEMNAGMP

ANKRD12

1646

Q6UB98
MSPCSCPQCVLVMSV

DTX4

186

Q9Y2E6
SEQRLTCADQMMPFG

DMAC2L

6

Q99766
HMLSSRLSMPDCPNC

FAM193A

191

P78312
ILAMVCGSQMSCPLT

ASTN2

446

O75129
GMADVGTMCDPKRSC

ADAMTS15

331

Q8TE58
NCRMVHMPGDAPFCT

ASIC2

321

Q16515
NGSICMRMEILGCPL

CPXM2

281

Q8N436
MCAEVGPALCRGMER

ISX

1

Q2M1V0
CPMDLKNFPMDVQTC

GLRA3

171

O75311
MAPPCGDMENLLCAT

ITPRIP

276

Q8IWB1
MPCLNGGTCAVASNM

NOTCH2

1311

Q04721
MTSAQCPALACVMSP

LRRC37A3

1

O60309
CRENTMCVNTPGSFM

NELL2

451

Q99435
SSTAMQCVPSDGCAM

IL17REL

11

Q6ZVW7
TRPAQDLLMSVCMNC

INTS1

381

Q8N201
DRGPCTLAQMAMRSA

DLEU7

106

Q6UYE1
NTEKGLMEVQRMCCP

LRRK1

1566

Q38SD2
VPMSRLCNGVQDCMD

LRP1

86

Q07954
PTWMRMSQGVCCNLE

PPFIA4

556

O75335
GMRPESQLACCDMVY

BSN

1891

Q9UPA5
LIMNPRGSCMANEKC

PCSK5

1441

Q92824
MGPRCECGEDMLSTD

ITGB6

486

P18564
CGFLNSFIMCPQTMQ

OR2W5P

151

A6NFC9
SFIMCPQTMQLSRCG

OR2W5P

156

A6NFC9
NCPETFTPDMRCIMG

PDPR

356

Q8NCN5
SMLGCELQAMLCVPV

PDE2A

321

O00408
GCRVTDAPCSNMLGM

NRP2

426

O60462
TMDNMTGLCRPVCAQ

MEGF8

2211

Q7Z7M0
MAGRSMQAARCPTDE

NSF

1

P46459
CPMRLVNFPMDGHAC

GABRA6

156

Q16445
GCATMDENIPSMEMC

ANO1

356

Q5XXA6
MMPSCNRSCSCSRGP

NRSN2

1

Q9GZP1
ACLGDPGSPMMCQLQ

PRSS54

216

Q6PEW0
PQMPSARECCSIVCM

KIF25-AS1

56

Q9Y6Z4
MMHCSACSENPPAGI

NBAS

1141

A2RRP1
MPLIMCPSQECQTNR

MCM7

201

P33993
QCNCMMGVFPPISRA

NUP155

101

O75694
GMNPCPMVLVFGCRQ

NOS1

1276

P29475
GLSAPFVAGQMDCCM

GCKR

181

Q14397
MDCCMNNTAVFLPVL

GCKR

191

Q14397
RCEMTSAPPLLCQMT

PRSS36

761

Q5K4E3
FMCNSSCVGGMNRRP

TP73

256

O15350
LAMDCGVNCFMLDPA

FBP1

176

P09467
FMCNSSCVGGMNRRP

TP63

306

Q9H3D4
LMPCDAALVAGECMV

ATP13A2

326

Q9NQ11
MAGLCPAACMQTPRM

FASTKD5

681

Q7L8L6
MGTCRMICDPYTAAP

C1QL2

26

Q7Z5L3
KCISCDRPVEMMTGP

C16orf96

911

A6NNT2
IMCVSMRGTICNPGP

DAGLB

76

Q8NCG7
GAGMCQVVVTCPMEM

SLC25A18

111

Q9H1K4
VGCMPLCSMDVRLPS

CCN2

131

P29279
LNCVTLGMYQPCDDM

CACNA1I

91

Q9P0X4
MATMLEGRCQTQPRS

GPAT2

1

Q6NUI2
PQMMDEVGRILCNLC

DDX12P

701

Q92771
VTMCMRCQEPFNALT

FGD2

461

Q7Z6J4
IGTFMCICPPGMARR

FBN2

2316

P35556
MLNCVTLGMFRPCED

CACNA1H

111

O95180
CQMFVGMRSPKLEEC

SPACA6

41

W5XKT8
MMCIACRGLAPEETN

CLDN18

191

P56856
PEMVCIDSCGRANGM

EXOSC3

176

Q9NQT5
IMEMAKNCNVDPRGC

CDC37L1

226

Q7L3B6
RCCQDGVTRLPMMRS

C4A

701

P0C0L4
GTMAERCSETSCPVM

MOB3C

76

Q70IA8
MLRYGPIQVECMSCS

PTPRK

1291

Q15262
TSMSPQLCALMLGVC

OR1N2

151

Q8NGR9
QMCPICLLGMLDEES

MAP3K1

441

Q13233
MRSFTCPSCMEPVDA

RNF11

131

Q9Y3C5
LCPQRGMCKSVFVME

FAN1

786

Q9Y2M0
MFNVCGTMPVCGTIL

IGF2R

966

P11717
MRHNQMCCETPPTVT

SPDYA

1

Q5MJ70
CLMLNPPNFCEMDGQ

SLPI

96

P03973
SECSMKEGIQTCMFP

TMEM131L

1071

A2VDJ0
MSALNGDCLMQPSRT

NEXMIF

131

Q5QGS0
CPMDLKNFPMDVQTC

GLRA1

166

P23415
ADLRIVMCAMCGDPF

ARHGAP5

776

Q13017
QPEELLCFSCQMCMA

STARD9

4111

Q9P2P6
MTCGPQGNRTMCEVG

ABCC12

826

Q96J65
PIEACVTMLLECGMQ

ARHGAP44

271

Q17R89
GLLCEFEITAMPCNM

SNED1

496

Q8TER0
FEITAMPCNMNTQCP

SNED1

501

Q8TER0
ENCNCRMVHMPGDAP

ASIC1

321

P78348
NCLGPQRSVCEMMKI

CLEC4A

221

Q9UMR7
TQNAEMRPLGCCMIL

PSMA6

126

P60900
LPVMQEPGCTMGICS

RNF14

316

Q9UBS8
AMDICATGPTACPVM

XYLT1

916

Q86Y38
DCPTCLPENRKVMDM

VPS11

856

Q9H270
SASGLPTMFPMTDCC

WDR70

416

Q9NW82
AGSVCLLMQVSMPCV

RTCA

96

O00442
VITGEGNMCTPQMPC

WBP2NL

156

Q6ICG8
MATHGQTCARPMCIP

VDAC2

1

P45880
MPFCDSGICPDIIMN

POLR3B

916

Q9NW08
CMVQCSQLSTGEPMI

VPS53

481

Q5VIR6
ECLPMPSMNSAAQFC

VPS41

821

P49754
CQMCDPAMGLRASRN

TNFRSF14

96

Q92956
CGMIMCLARQIPQAT

PHGDH

111

O43175
DSPLGLCQSECMEMS

ZBTB38

886

Q8NAP3
ETQSCSLMCPNECVM

THSD7B

1116

Q9C0I4
CMDEECMLPSEPSSS

HIVEP2

2021

P31629
EMVFVCGTNAFNPMC

SEMA6D

131

Q8NFY4
CNQASMGCQAPKPDM

ZFP37

66

Q9Y6Q3
CSKAPAQTQMCPQMS

ZNF438

146

Q7Z4V0
MDQPSGRSFMQVLCE

TBCEL

1

Q5QJ74
CEMCETPQGSAVMQI

ZRANB3

641

Q5FWF4
MIASVPGCGTAAMEC

UNC79

2306

Q9P2D8
CMMQTCSFDIPNDLC

ZAN

206

Q9Y493
CACPDGMLLARDMRS

LDLR

696

P01130