Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentprotein phosphatase type 2A complex

PPP2R2B PPP2R2C PPP2R2D

2.48e-0518673GO:0000159
GeneOntologyCellularComponentprotein serine/threonine phosphatase complex

PPP2R2B PPP2R2C PPP2R2D

7.33e-0455673GO:0008287
GeneOntologyCellularComponentphosphatase complex

PPP2R2B PPP2R2C PPP2R2D

7.33e-0455673GO:1903293
DomainPP2A_PR55

PPP2R2B PPP2R2C PPP2R2D

1.76e-074673IPR000009
DomainPP2A_PR55_CS

PPP2R2B PPP2R2C PPP2R2D

1.76e-074673IPR018067
DomainPR55_2

PPP2R2B PPP2R2C PPP2R2D

1.76e-074673PS01025
DomainPR55_1

PPP2R2B PPP2R2C PPP2R2D

1.76e-074673PS01024
Domain-

MET NBAS VPS11 PPP2R2B PPP2R2C PPP2R2D NUP43 HPS5

2.45e-053336782.130.10.10
DomainWD40/YVTN_repeat-like_dom

MET NBAS VPS11 PPP2R2B PPP2R2C PPP2R2D NUP43 HPS5

2.56e-05335678IPR015943
DomainWD40_repeat_dom

VPS11 PPP2R2B PPP2R2C PPP2R2D UBR4 NUP43 HPS5

9.21e-05297677IPR017986
DomainDUF3398

DOCK8 DOCK6

1.88e-046672PF11878
DomainDOCK_C/D_N

DOCK8 DOCK6

1.88e-046672IPR021816
DomainOlfact_rcpt

OR8H2 OR1L8 OR51B5 OR52E6 OR10K2 OR51V1 OR2T4

5.08e-04393677IPR000725
DomainGPCR_Rhodpsn_7TM

OR8H2 OR1L8 OR51B5 GPR21 OR52E6 OR10K2 GPR52 OR51V1 OR2T4

6.21e-04670679IPR017452
Domain7tm_1

OR8H2 OR1L8 OR51B5 GPR21 OR52E6 OR10K2 GPR52 OR51V1 OR2T4

6.69e-04677679PF00001
DomainDOCK_C

DOCK8 DOCK6

6.83e-0411672IPR010703
DomainDHR-1_domain

DOCK8 DOCK6

6.83e-0411672IPR027007
DomainDHR_2

DOCK8 DOCK6

6.83e-0411672PS51651
DomainDHR_1

DOCK8 DOCK6

6.83e-0411672PS51650
DomainDOCK-C2

DOCK8 DOCK6

6.83e-0411672PF14429
DomainDHR-2

DOCK8 DOCK6

6.83e-0411672IPR027357
DomainDHR-2

DOCK8 DOCK6

6.83e-0411672PF06920
DomainDOCK

DOCK8 DOCK6

6.83e-0411672IPR026791
DomainG_PROTEIN_RECEP_F1_1

OR8H2 OR1L8 OR51B5 GPR21 OR52E6 OR10K2 GPR52 OR51V1 OR2T4

7.27e-04685679PS00237
DomainG_PROTEIN_RECEP_F1_2

OR8H2 OR1L8 OR51B5 GPR21 OR52E6 OR10K2 GPR52 OR51V1 OR2T4

7.74e-04691679PS50262
DomainGPCR_Rhodpsn

OR8H2 OR1L8 OR51B5 GPR21 OR52E6 OR10K2 GPR52 OR51V1 OR2T4

7.82e-04692679IPR000276
DomainWD_REPEATS_1

NBAS PPP2R2B PPP2R2C PPP2R2D NUP43

3.21e-03278675PS00678
DomainWD_REPEATS_2

NBAS PPP2R2B PPP2R2C PPP2R2D NUP43

3.26e-03279675PS50082
DomainWD_REPEATS_REGION

NBAS PPP2R2B PPP2R2C PPP2R2D NUP43

3.26e-03279675PS50294
DomainARM-type_fold

USP34 VPS11 DOCK8 UBR4 TNPO3

7.37e-03339675IPR016024
PathwayKEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY

PPP2R2B PPP2R2C PPP2R2D

4.15e-0519513M47525
PathwayKEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY

PPP2R2B PPP2R2C PPP2R2D

6.54e-0522513M47919
Pubmed

HSF1 transcriptional activity is modulated by IER5 and PP2A/B55.

PPP2R2B PPP2R2C PPP2R2D

2.38e-07767325816751
Pubmed

Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development.

PPP2R2B PPP2R2C PPP2R2D

5.69e-07967319762425
Pubmed

The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM, and inhibits neuronal adhesion and neurite outgrowth.

NCAN L1CAM

3.66e-0626727513709
Pubmed

Characterization of the L1-neurocan-binding site. Implications for L1-L1 homophilic binding.

NCAN L1CAM

3.66e-06267210934197
Pubmed

Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development.

PPP2R2B PPP2R2C PPP2R2D

6.48e-061967332582689
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP34 ISLR2 PITRM1 PPP2R2D CACNA1G HPS5 DOCK6 METTL14

8.07e-0652967814621295
Pubmed

Essential Role of Linx/Islr2 in the Development of the Forebrain Anterior Commissure.

ISLR2 L1CAM

1.10e-05367229739947
Pubmed

Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits.

PPP2R2B PPP2R2C

1.10e-0536729514514
Pubmed

Aberrant trajectory of thalamocortical axons associated with abnormal localization of neurocan immunoreactivity in the cerebral neocortex of reeler mutant mice.

NCAN L1CAM

2.19e-05467216324103
Pubmed

Activation of protein phosphatase-2A1 by HIV-1 Vpr cell death causing peptide in intact CD(4+) T cells and in vitro.

PPP2R2B PPP2R2C

3.64e-05567215578586
Pubmed

Breakpoint features of genomic rearrangements in neuroblastoma with unbalanced translocations and chromothripsis.

NBAS TENM4

3.64e-05567223991058
Pubmed

Disentangling the Roles of RIM and Munc13 in Synaptic Vesicle Localization and Neurotransmission.

ABCA4 UNC13A

3.64e-05567233139401
Pubmed

Coordinate expression of L1 and 6B4 proteoglycan/phosphacan is correlated with the migration of mesencephalic dopaminergic neurons in mice.

NCAN L1CAM

5.46e-0566729593903
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 TENM4 CACNA1G HPS5 CLEC16A

7.55e-0522567512168954
Pubmed

Selective proteasomal degradation of the B'β subunit of protein phosphatase 2A by the E3 ubiquitin ligase adaptor Kelch-like 15.

PPP2R2B PPP2R2D

7.63e-05767223135275
Pubmed

The human olfactory receptor gene family.

OR8H2 OR1L8 OR51B5 OR52E6 OR10K2 OR51V1 OR2T4

8.23e-0554167714983052
Pubmed

Genome-wide association study reveals two new risk loci for bipolar disorder.

TENM4 NCAN

1.02e-04867224618891
Pubmed

Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A.

PPP2R2B PPP2R2C

1.02e-04867212912990
Pubmed

The role of Vpr in HIV-1 pathogenesis.

PPP2R2B PPP2R2C

1.02e-04867215638722
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

ANKRD44 CNNM4 MET PPP2R2B PPP2R2C PPP2R2D UBR4

1.18e-0457367728330616
Pubmed

Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice.

NCAN L1CAM

1.63e-04106729184108
Pubmed

Linx mediates interaxonal interactions and formation of the internal capsule.

ISLR2 L1CAM

1.99e-041167224930700
Pubmed

Bacterial inhibition of Fas-mediated killing promotes neuroinvasion and persistence.

MET PRF1

1.99e-041167235296858
Pubmed

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.

PPP2R2B TENM4 ANKS1B

2.74e-046567323453885
Pubmed

Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29.

PPP2R2B PPP2R2C

2.81e-041367218971272
Pubmed

Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr.

PPP2R2B PPP2R2C

3.28e-04146729013886
Pubmed

Increasing the ratio of PP2A core enzyme to holoenzyme inhibits Tat-stimulated HIV-1 transcription and virus production.

PPP2R2B PPP2R2C

3.28e-04146729400615
Pubmed

Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.

PPP2R2B PPP2R2C

3.28e-041467216048649
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK8 DOCK6

3.28e-041467212432077
Pubmed

Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

OR51B5 OR51V1

3.78e-041567211121057
Pubmed

Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration.

PPP2R2B PPP2R2C

3.78e-041567216041367
Pubmed

Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study.

PPP2R2B TENM4

4.31e-041667217903297
Pubmed

Regulation of HIV-1 transcription by protein phosphatase 1.

PPP2R2B PPP2R2C

4.88e-041767217266553
Pubmed

[Action of protein phosphatase-1 on Tat-dependent HIV-1 transcription and its related inhibitors].

PPP2R2B PPP2R2C

4.88e-041767221351466
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR8H2 OR1L8 OR10K2 OR51V1 OR2T4

5.10e-0434067511875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR8H2 OR1L8 OR10K2 OR51V1 OR2T4

5.10e-0434067511802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR8H2 OR1L8 OR10K2 OR51V1 OR2T4

5.30e-0434367532295537
Pubmed

Molecular mechanisms involved in HIV-1-Tat mediated inhibition of telomerase activity in human CD4(+) T lymphocytes.

PPP2R2B PPP2R2C

5.48e-041867223287597
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR8H2 OR1L8 OR10K2 OR51V1 OR2T4

5.52e-0434667514611657
Pubmed

LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons.

STRADA L1CAM

6.12e-041967217482548
Pubmed

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.

CNNM4 TENM4

6.12e-041967218711365
Pubmed

Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.

ZNF221 ZNF235

6.79e-042067212743021
Pubmed

Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

ANKS1B UNC13A

7.50e-042167222959728
Pubmed

TCF7L2 regulates postmitotic differentiation programmes and excitability patterns in the thalamus.

L1CAM CACNA1G

8.24e-042267232675279
Pubmed

The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells.

ISLR2 UBR4

9.82e-042467235179492
Pubmed

Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.

MET FLT3

1.07e-032567215254900
Pubmed

An integrated workflow for charting the human interaction proteome: insights into the PP2A system.

PPP2R2B PPP2R2C PPP2R2D

1.11e-0310567319156129
Pubmed

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.

CLEC16A TNPO3

1.15e-032667221399635
Pubmed

AP2gamma regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex.

TFAP2D L1CAM

1.15e-032667219749747
Pubmed

HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25.

PPP2R2B PPP2R2C

1.15e-032667211531413
Pubmed

Genome-wide association studies and heritability estimates of body mass index related phenotypes in Bangladeshi adults.

RGMA TFAP2D

1.24e-032767225133637
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

HIPK3 USP34 MET PPP2R2D STRADA DDX60L LIMS2

1.83e-0391067736736316
InteractionSERTAD4 interactions

PPP2R2B PPP2R2C PPP2R2D ZNF235

3.46e-0719644int:SERTAD4
InteractionIER5 interactions

PPP2R2B PPP2R2C PPP2R2D

8.54e-0613643int:IER5
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2B PPP2R2C PPP2R2D

6.42e-0615453696
CoexpressionGSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY7_UP

LGMN ATXN7L2 UBR4 MARF1 DOCK6 ARHGEF16

1.04e-05200656M9338
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP2R2B PPP2R2C L1CAM ANKS1B ARHGEF16

8.98e-06186675ea936e66ae4b7b40564711fad60ac0137327995f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD44 PPP2R2B FLT3 DOCK8 BATF

1.10e-051946754dfc890bacf133cfb6ec7c8b73f084f2491cf78e
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD44 PPP2R2B DOCK8 BATF PRF1

1.27e-052006755f41906cf1585e09b150a84364d47c3e466dc5b7
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD44 PPP2R2B DOCK8 BATF PRF1

1.27e-05200675dbbc7e16929e744b48017da068479a6046e99cf6
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LGMN PPP2R2B FLT3 NCAN

4.17e-05128674cfc73cb803ba50a4a8709e19e70e1e399118c849
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell|343B / Donor, Lineage, Cell class and subclass (all cells)

ANKRD44 PRF1 DGKK UNC13A

5.28e-05136674b4a934feea46eeb10d407d1545bd225173078792
ToppCellCOVID-19_Mild-Neu_0|World / 5 Neutrophil clusters in COVID-19 patients

TENM4 OR51V1 UNC13A KYAT1

5.91e-0514067493f024473b1bb3bf93ae776fd6a8fc5e93d013f0
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|368C / Donor, Lineage, Cell class and subclass (all cells)

PPP2R2B ATXN7L2 PRF1 ZNF235

7.14e-051476743ed5b020ce1f1277917d79ef1f7da53fa474e8db
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell|368C / Donor, Lineage, Cell class and subclass (all cells)

PPP2R2B ATXN7L2 PRF1 ZNF235

7.93e-05151674512f7f37ddc8dfa1906f7fff92b571929236c9ea
ToppCellRV-17._Lymphocyte|RV / Chamber and Cluster_Paper

ANKRD44 PPP2R2B DOCK8 PRF1

8.34e-05153674e1ea621184014415870e00d511386b8cc3e0833b
ToppCell367C-Lymphocytic-ILC-ILC-1|367C / Donor, Lineage, Cell class and subclass (all cells)

PPP2R2B BATF PRF1 L1CAM

1.04e-0416267474cd0de957fdbe527656befd61f67d6814ce9e98
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ISLR2 PPP2R2B PPP2R2C L1CAM

1.12e-041656749795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCellControl-T_cells-Tregs|Control / group, cell type (main and fine annotations)

ANKRD44 PPP2R2B DOCK8 BATF

1.22e-04169674e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD44 PPP2R2B PRF1 DGKK

1.25e-0417067428fb192b21cdc5a77ba4f276694cff852eb2304b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD44 PPP2R2B PRF1 DGKK

1.25e-04170674239cb4b801b2d71a6facb386f2684c0851504151
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPP2R2B ATXN7L2 PRF1 DGKK

1.28e-04171674187b396059f8802265f54bad2b4882cebb809419
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP2R2C ABCA4 GPR21 NCAN

1.53e-04179674a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellAdult-Immune-T_lymphocyte-D122|Adult / Lineage, Cell type, age group and donor

ANKRD44 PPP2R2B DOCK8 BATF

1.56e-0418067406c371d0f0c5a7b234dd143e98800e19af95a8b5
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLHL38 PADI4 DOCK8 BATF

1.56e-041806741c5515f29ead129bee3b4ca27799796956811a39
ToppCellFLU-Healthy-0|FLU / Virus stimulation, Condition and Cluster

ANKRD44 L1CAM ZNF221 LIMS2

1.66e-04183674058604ddb06b3bef131183d86b83b422dae8f6cb
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP2R2C ABCA4 GPR21 NCAN

1.66e-041836746f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP2R2B L1CAM ANKS1B ARHGEF16

1.66e-041836742cf36ad89584eb9f8b04de52a1b511b7f3527884
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP2R2B L1CAM ANKS1B ARHGEF16

1.66e-0418367498fee6838acfaee5e2e449ba088764ec06b8bc57
ToppCellRA-17._Lymphocyte|World / Chamber and Cluster_Paper

PPP2R2B DOCK8 BATF PRF1

1.66e-041836746397f684a50346fc42cccb5afbe10350f4b2d9b0
ToppCellFLU-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

ANKRD44 L1CAM ZNF221 LIMS2

1.66e-041836747a6f18246c39864479e114f698581f667fa9c600
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ISLR2 PPP2R2B L1CAM UNC13A

1.70e-04184674571136c832cb8c08457744152231537aa8e8abd7
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP2R2C ABCA4 GPR21 NCAN

1.70e-04184674f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP2R2C ABCA4 GPR21 NCAN

1.70e-041846748bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP2R2B L1CAM ANKS1B ARHGEF16

1.70e-04184674da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCellControl-T_cells-CD8+_T_cells|Control / group, cell type (main and fine annotations)

ANKRD44 PPP2R2B DOCK8 PRF1

1.73e-0418567402ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell18-Distal-Epithelial-Epithelial|Distal / Age, Tissue, Lineage and Cell class

PPP2R2B PPP2R2C L1CAM UNC13A

1.73e-04185674d2a266724f3f70f746a78034f308d98f8b7a66e3
ToppCellControl-T_cells-NK_cells|Control / group, cell type (main and fine annotations)

ANKRD44 PPP2R2B PRF1 DGKK

1.73e-04185674755c0998c729f462399f1d5e88adf4bfae31be30
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPP2R2B L1CAM ANKS1B UNC13A

1.77e-0418667424b23880d4ff8fb4a23e2012d5890b9e2fcf7283
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANKRD44 LGMN DOCK8 CH25H

1.81e-04187674ba822dbceb47257129d6a8c9639c08d76de6d6a3
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

ANKRD44 PPP2R2B DOCK8 PRF1

1.81e-04187674f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCellASK454-Epithelial-Type_1|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

CNNM4 HCFC1R1 UBALD1 LIMS2

1.84e-0418867413f8ce8f24ac7d7ed87f4ae3b8f4096de29383c2
ToppCellCOVID-19-kidney-T-cells-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANKRD44 PPP2R2B BATF PRF1

1.84e-0418867415484c05cb496cd98ed3f79a6134c5cec8f09a4d
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ISLR2 PPP2R2B DGKK L1CAM

1.88e-04189674cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPP2R2B BATF PRF1 L1CAM

1.92e-04190674ce049630ed69d31f00acbc1b5b0896efc592121f
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

L1CAM ANKS1B GPR52 ARHGEF16

1.92e-04190674ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCellControl-T_cells-CD4+_T_cells|Control / group, cell type (main and fine annotations)

ANKRD44 PPP2R2B DOCK8 BATF

1.92e-041906740733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

L1CAM ANKS1B GPR52 ARHGEF16

1.92e-041906744971857eac9af17d66d673ed2ab7072639f60a10
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ISLR2 PPP2R2B L1CAM UNC13A

1.96e-041916743a5081dc542ac6262acfe5f8084a86616fee8082
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD44 PPP2R2B DOCK8 BATF

1.96e-04191674d9506b88d806aadd4c2b9bf86fe994c47799e7f6
ToppCellcontrol-Lymphoid-CTL|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ANKRD44 PPP2R2B DOCK8 PRF1

1.96e-041916748df23473e24cfa51c09986102ddd391ed0f0b9cc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD44 PPP2R2B DOCK8 BATF

1.96e-04191674b42c54308abe1241cc38ddce96b9d38d07983891
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD44 DOCK8 BATF PRF1

1.96e-0419167496a7179a845d3daa046ed71fa45c51255f130a7f
ToppCellCOVID-19-lung-CD8+_T_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANKRD44 PPP2R2B DOCK8 PRF1

1.96e-04191674543f8ae07cc2e6950c888115a5ca9445e3c0f618
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD44 PPP2R2B DOCK8 BATF

1.96e-041916749aabbc65430e2233b8f2d3fff9face7807b88b48
ToppCellCOPD-Lymphoid|COPD / Disease state, Lineage and Cell class

ANKRD44 PPP2R2B BATF PRF1

2.00e-04192674064fefb8212fadab0ff441f4bf643559b7fdb25d
ToppCellCOVID-19-kidney-Myeloid|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANKRD44 PADI4 DOCK8 DDX60L

2.00e-041926740b9d22a222f1201e375f8e55cace9ef939febae4
ToppCellIPF-Lymphoid|IPF / Disease state, Lineage and Cell class

ANKRD44 PPP2R2B BATF PRF1

2.04e-04193674bf9d50aea909a28dd1d0933af33842d5f1ae7818
ToppCellhuman_hepatoblastoma-NK.T_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

ANKRD44 DOCK8 BATF PRF1

2.08e-04194674997b02a22d7c89a8fd5615bb79a2a8a34fc3fee6
ToppCellControl-Lymphoid|Control / Disease state, Lineage and Cell class

ANKRD44 PPP2R2B BATF PRF1

2.08e-04194674d5b124f15c953eeb7e8e990df44d7fa466f2b31f
ToppCellCOVID-19-lung-CD4+_T_cells_metabolically_active|lung / Disease (COVID-19 only), tissue and cell type

ANKRD44 PPP2R2B DOCK8 PRF1

2.08e-041946742a144a1c2d537c8a59aa419206ddd96c23f0aeab
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ANKRD44 PPP2R2B BATF PRF1

2.12e-04195674ffb40486f8097b2c08e8f3b3685d0b8cb8d1bc66
ToppCellnucseq-Immune-Lymphocytic_T/NK|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ANKRD44 PPP2R2B BATF PRF1

2.12e-04195674b8124e8a23e6d37b40023608674e67285c6ffe84
ToppCelldistal-Hematologic-Natural_Killer_T-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPP2R2B BATF PRF1 L1CAM

2.16e-0419667405d2a15ba702b07ef59c55891a06da02cdd15f7f
ToppCelldistal-Hematologic-Natural_Killer_T|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPP2R2B BATF PRF1 L1CAM

2.20e-041976745cb1b45f5dc8fbd9e54db9c943450ce2cc7000e4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD44 LGMN FLT3 DOCK8

2.20e-041976748af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

PADI4 FLT3 DOCK8 DDX60L

2.20e-04197674a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellTransverse-T_cell-Treg|T_cell / Region, Cell class and subclass

LGMN PADI4 BATF ANKS1B

2.20e-04197674b7a1637e4baadd657f6279f4aa96cd590c9cd8c9
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD44 PADI4 FLT3 HPS5

2.25e-0419867433690e16e4549b110e5b67f84b9515c696fe05e1
ToppCelldistal-3-Hematologic-Natural_Killer_T|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPP2R2B BATF PRF1 L1CAM

2.25e-04198674b5da18f2a3554dca36e88be3b96a89089c2f2e1d
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD44 PPP2R2B DOCK8 BATF

2.29e-04199674bc93e5c36ab60b66fb633c954b05d4dc09a7f152
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-T-T_CD3-NKT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PRF1 NCAN DGKK

2.29e-041996748a64437fecdf0b13247f2582bd2ab55ab58f8066
ToppCelldistal-1-Hematologic-CD8+_Naive_T|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPP2R2B BATF PRF1 DGKK

2.29e-0419967456eca2f1e6ac1bba0a742a1824c54d0d97541ff1
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-T-T_CD3|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R2B PRF1 NCAN DGKK

2.29e-041996743bf6d35e0f9be58f01a0b43cb707635595186bb0
ToppCellTracheal-10x5prime-Immune_Lymphocytic-T-T_CD8-CD8|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD44 PPP2R2B DOCK8 PRF1

2.29e-04199674c3aa72555fa3c2a0d85172682972d91fd9bb7b6a
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD44 PPP2R2B DOCK8 BATF

2.29e-04199674fbdde57dd88656621801e65ee2818251588f3874
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD44 PPP2R2B DOCK8 BATF

2.33e-04200674d8459e45a8396a9ee063666a1928c649162c5727
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal-BMP_responsible_cell|GW23 / Sample Type, Dataset, Time_group, and Cell type.

LGMN DOCK8 CH25H DOCK6

2.33e-0420067401d707c4f8ee0daac635b7260937b1baebc6fc23
ToppCellBiopsy_IPF-Immune-T_cells|Biopsy_IPF / Sample group, Lineage and Cell type

ANKRD44 PPP2R2B BATF PRF1

2.33e-04200674368c7334d211054f1e914a1be4027aa75e2df66c
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD44 PPP2R2B DOCK8 BATF

2.33e-0420067420ffb3436d08042f77800513e6ddb3bbc38ae6fe
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANKRD44 USP34 DOCK8 DDX60L

2.33e-0420067412f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD44 PPP2R2B DOCK8 BATF

2.33e-042006748474e5d031d25bfb8461d39fa2053da01a6304fc
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD44 PPP2R2B DOCK8 PRF1

2.33e-0420067413d8c5d65d7f900979319433e7044efa6d06de20
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD44 PPP2R2B DOCK8 PRF1

2.33e-04200674893bb7c25ad7c6589a4c7c0364c2ace666e9b4be
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD44 PPP2R2B DOCK8 BATF

2.33e-042006749de4d6ebb7e9bee5d811519eb05913ef30f70786
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal|GW10 / Sample Type, Dataset, Time_group, and Cell type.

ANKRD44 PPP2R2B NCAN L1CAM

2.33e-0420067404699d1149a143b96d6f292c0d70c4d3e6dfc611
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-gdT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD44 PADI4 PPP2R2B DOCK8

2.33e-042006749996803c35444d32b76ab78b716674c3743f155a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Cortical_neuron|6m / Sample Type, Dataset, Time_group, and Cell type.

PPP2R2B L1CAM ANKS1B UNC13A

2.33e-042006746f7ff0533339fcc9d316f2c77334a79c1409ec4f
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2B PPP2R2C PPP2R2D

2.01e-0612633DOID:1441 (implicated_via_orthology)
Diseaseeosinophil measurement

ANKRD44 USP34 LGMN CLEC16A

8.56e-05108634EFO_0803540
DiseaseThromboembolism

OR51B5 DOCK8 OR51V1

1.15e-0444633HP_0001907
Diseasebipolar I disorder

CNNM4 TENM4 NCAN ANKS1B

2.39e-04141634EFO_0009963
Diseaseoral squamous cell carcinoma (is_marker_for)

MET FLT3 DOCK6

3.36e-0463633DOID:0050866 (is_marker_for)
Diseasemultiple sclerosis (is_implicated_in)

RGMA PRF1 CLEC16A

5.19e-0473633DOID:2377 (is_implicated_in)
Diseaserenal fibrosis (implicated_via_orthology)

GPR21 GPR52

5.98e-0417632DOID:0050855 (implicated_via_orthology)
Diseaseattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia

PPP2R2B TENM4 ANKS1B

1.33e-03101633EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090

Protein segments in the cluster

PeptideGeneStartEntry
HVQYTCLHENLFHFV

UNC13A

816

Q9UPW8
TAAEFHPHHCNTFVY

PPP2R2B

226

Q00005
TASEFHPHHCNLFVY

PPP2R2C

226

Q9Y2T4
HPHHCNLFVYSSSKG

PPP2R2C

231

Q9Y2T4
SAHEFLFHYCGQHLH

ARSD

451

P51689
HFNTTHLLALCDYFH

C8orf74

101

Q6P047
NPLYSHHECHFPNKA

ABCA4

46

P78363
HAEKHFHPYIAYCSN

ARHGEF16

366

Q5VV41
TAAEFHPHQCNVFVY

PPP2R2D

236

Q66LE6
HCPAHDDFYLVVCNH

ATXN7L2

71

Q5T6C5
HQSFHYEFQHSHPAV

TFAP2D

71

Q7Z6R9
SALSHLQLYHNPFHC

ISLR2

171

Q6UXK2
EVHFHPSNPEHLFTC

NUP43

266

Q8NFH3
NHHYCHVFTAFDVNL

ANKS1B

1156

Q7Z6G8
NDFFTYHIRHGEVHC

PADI4

631

Q9UM07
LHFYDSNVIHHFFCD

OR8H2

166

Q8N162
YFAHHPAFAHFETID

DGKK

246

Q5KSL6
SDAYHPDHFNCTHCG

LIMS2

156

Q7Z4I7
DHHTHENGYNPHCIF

LINS1

481

Q8NG48
LHHLYNASCHPAFPV

IRF1-AS1

46

Q8N8D9
HNDYCQHFVDTGHRP

METTL14

116

Q9HCE5
QLCHHHPAEFLAYLD

HPS5

881

Q9UPZ3
DDVYFDHFHPCAALT

DDX60L

976

Q5H9U9
KSHPHTECHSYVFAI

DDX60L

1136

Q5H9U9
IHCDAHLHTPMYFFI

OR2T4

81

Q8NH00
YCHSHVLSHAFCLHQ

OR51B5

166

Q9H339
NYCHFHILSHSFCLH

OR51V1

176

Q9H2C8
FTHCFGHDIPQYIHI

OR52E6

261

Q96RD3
CRFYSFHVVHTPPLH

PRF1

176

P14222
IHHVSPHETYFCITT

PEDS1

216

A5PLL7
FSQAVTPLAHHHTDY

MANSC1

146

Q9H8J5
SDNHSDYICHAHFPG

L1CAM

201

P32004
PLHYAAANCHFHCIE

ANKRD44

441

Q8N8A2
DQGCHPYVDHYDHTI

PLA2G2F

76

Q9BZM2
VIFVFHCAPLLHHYT

GPR52

61

Q9Y2T5
HCAPLLHHYTTSYFI

GPR52

66

Q9Y2T5
LDFPHSNHVKSCFHI

HIPK3

531

Q9H422
SHCFSFSSHYPHGIN

NBAS

226

A2RRP1
FCNHKHQPGEYIFHA

FLT3

406

P36888
HHLLFTFYHVSCQPR

DOCK6

631

Q96HP0
VNHHLLFTFYHISCQ

DOCK8

641

Q8NF50
ESVHSFYHADCHLEP

CACNA1G

551

O43497
VVYSAHAFHQPHVSS

BATF

106

Q16520
FAAHHLPECTFTKAH

C9orf43

66

Q8TAL5
PSYHHHFAKQCRVSD

MARF1

1126

Q9Y4F3
THFSQLSLHNDHPYC

HCFC1R1

66

Q9NWW0
FVFHCAPLLNHHTTS

GPR21

51

Q99679
LHHSHFNCNFAPYFT

CH25H

241

O95992
AVCDPFHYVTTMSHH

OR1L8

126

Q8NGR8
VAFSCSFPHLHSLLH

OR1L8

146

Q8NGR8
LPFYSSNQLHHFFCD

OR10K2

166

Q6IF99
LQHFYGPNHEHCFNR

MET

386

P08581
RTFSPHFHHFVEQCL

STRADA

346

Q7RTN6
SDVHCLSHPHFTTLY

PKDREJ

1261

Q9NTG1
SVPHQKHFDHYIRFC

KYAT1

386

Q16773
FDAYCFRAHHPTSQH

NCAN

351

O14594
KQFHATHYHPSNARF

PITRM1

251

Q5JRX3
QPHLAFLHICTHAFF

MT-ND5

321

P03915
FHKHSATPNYTHCGL

RGMA

151

Q96B86
HTVHFFYNEHTNDFA

CLEC16A

156

Q2KHT3
ITRFYNHPVHFVFHD

CNNM4

441

Q6P4Q7
FLCGHSFHQHCFESY

VPS11

836

Q9H270
HHSTHFLENYYNCNE

ZNF519

171

Q8TB69
CHFTYPASHDLHLAQ

TEX37

106

Q96LM6
HSHHLQFFYADLTNP

TENM4

2306

Q6N022
VYHVHQHSCFLYLGS

TNPO3

691

Q9Y5L0
AFNYHHSFQTQERPH

ZNF442

161

Q9H7R0
SFCYSPALHIHQRVH

ZNF221

206

Q9UK13
PFLQHNHCTYHHSNI

USP34

3071

Q70CQ2
SHFNIVHYDCHLAAV

UBR4

4881

Q5T4S7
APYVDIFSCISHHHD

ZNF235

211

Q14590
FFQETNIPYSHHHHQ

UBALD1

46

Q8TB05
YIHPAFFHHFIANDA

KLHL38

226

Q2WGJ6
HSCYPEALLHFRTHC

LGMN

376

Q99538