Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase activator activity	GAPVD1 PGAM5 TIAM2 JUN TBC1D1 RAB3GAP2 RASA4B AGAP4 ARHGEF19 WNT11 RALGAPB RASA4 AGAP7P ARHGAP33	8.83e-06	279	243	14	GO:0005096
GeneOntologyMolecularFunction	Roundabout binding	LGR4 SLIT2 IGFALS SLIT1	9.81e-06	12	243	4	GO:0048495
GeneOntologyMolecularFunction	MAP kinase tyrosine/serine/threonine phosphatase activity	DUSP5 DUSP8 DUSP14 DUSP16	1.40e-05	13	243	4	GO:0017017
GeneOntologyMolecularFunction	MAP kinase phosphatase activity	DUSP5 DUSP8 DUSP14 DUSP16	5.73e-05	18	243	4	GO:0033549
GeneOntologyMolecularFunction	enzyme activator activity	ERBB3 GAPVD1 WRNIP1 PGAM5 TIAM2 TAOK2 JUN TBC1D1 ANGPT4 RAB3GAP2 RASA4B GNAS AGAP4 ARHGEF19 WNT11 RALGAPB RASA4 AGAP7P POLG2 ARHGAP33	1.63e-04	656	243	20	GO:0008047
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	GAPVD1 PGAM5 TIAM2 PLEKHG1 SLIT2 JUN TBC1D1 RAB3GAP2 GPSM2 RASA4B AGAP4 ARHGEF19 WNT11 RALGAPB RASA4 AGAP7P ARHGAP33	1.69e-04	507	243	17	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	GAPVD1 PGAM5 TIAM2 PLEKHG1 SLIT2 JUN TBC1D1 RAB3GAP2 GPSM2 RASA4B AGAP4 ARHGEF19 WNT11 RALGAPB RASA4 AGAP7P ARHGAP33	1.69e-04	507	243	17	GO:0030695
GeneOntologyMolecularFunction	MAP kinase tyrosine phosphatase activity	DUSP5 DUSP8 DUSP16	2.01e-04	10	243	3	GO:0033550
GeneOntologyMolecularFunction	protein tyrosine/threonine phosphatase activity	DUSP5 DUSP8 DUSP16	2.73e-04	11	243	3	GO:0008330
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	SPSB2 PRAMEF22 PRAMEF19 PRAMEF18 KLHL22 KLHDC10	4.94e-04	82	243	6	GO:1990756
GeneOntologyMolecularFunction	myosin phosphatase activity	PPM1M PGAM5 DUSP5 DUSP8 DUSP14 DUSP16	5.99e-04	85	243	6	GO:0017018
GeneOntologyBiologicalProcess	in utero embryonic development	SLC39A1 NSUN2 SLIT2 BTF3 HES1 MAFF MYO18B NOTCH2 NLRP5 PLOD3 PRAMEF22 PRAMEF19 PRAMEF18 AR EDNRA RTL1 ARMC5 CCNB1IP1 SYVN1 POLG2 SMAD2	7.08e-06	596	240	21	GO:0001701
GeneOntologyBiologicalProcess	embryo development	PCSK5 SLC39A1 TMEM94 NSUN2 SEMA3A SLIT2 USH1G BTF3 DLG3 HES1 MAFF LOXL3 GNAS MYO18B CPLANE1 NOTCH2 NLRP5 PLOD3 DYNC2H1 PRAMEF22 PRAMEF19 DUSP5 WNT11 DYNC2I1 PRAMEF18 AR EDNRA CELSR1 RTL1 MICAL2 ARMC5 SCRIB CCNB1IP1 SYVN1 POLG2 SMAD2	1.08e-05	1437	240	36	GO:0009790
GeneOntologyBiologicalProcess	chordate embryonic development	PCSK5 SLC39A1 NSUN2 SLIT2 BTF3 HES1 MAFF GNAS MYO18B NOTCH2 NLRP5 PLOD3 PRAMEF22 PRAMEF19 DYNC2I1 PRAMEF18 AR EDNRA CELSR1 RTL1 ARMC5 SCRIB CCNB1IP1 SYVN1 POLG2 SMAD2	2.18e-05	906	240	26	GO:0043009
GeneOntologyBiologicalProcess	Golgi organization	CUL7 SPTBN5 COG1 HACE1 GOLGA5 GOLGB1 DYNC2H1 SYNE1 HUWE1 AKAP9	2.85e-05	168	240	10	GO:0007030
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	PCSK5 SLC39A1 NSUN2 SLIT2 BTF3 HES1 MAFF GNAS MYO18B NOTCH2 NLRP5 PLOD3 PRAMEF22 PRAMEF19 DYNC2I1 PRAMEF18 AR EDNRA CELSR1 RTL1 ARMC5 SCRIB CCNB1IP1 SYVN1 POLG2 SMAD2	3.33e-05	929	240	26	GO:0009792
GeneOntologyBiologicalProcess	regulation of GTPase activity	GAPVD1 TIAM2 TBC1D1 RAB3GAP2 RASA4B RIPOR1 AGAP4 ARHGEF19 WNT11 RALGAPB RASA4 SCRIB AGAP7P MMUT	4.11e-05	335	240	14	GO:0043087
GeneOntologyBiologicalProcess	cell cycle process	CCP110 CENPF CCNP MCM2 TUBGCP2 CUL7 TUBGCP5 NSUN2 FANCA TAOK2 STARD9 KLHL21 RECQL4 FES CRNN GPSM2 MTCL1 ANAPC4 KIF22 NLRP5 DDX12P MIS18A CEP192 MAU2 PSTPIP1 XRCC3 EDNRA KLHL22 CEP250 SMARCD3 ZFYVE26 TNKS CCNB1IP1 TP53BP1	6.51e-05	1441	240	34	GO:0022402
GeneOntologyCellularComponent	spindle pole	CENPF TUBGCP2 TUBGCP5 KLHL21 GPSM2 MTCL1 DDX12P DYNC2I1 KLHL22 CEP250 TNKS	2.96e-05	205	243	11	GO:0000922
MousePheno	abnormal urinary bladder morphology	PCSK5 HPSE2 BTF3 PLOD3 PRAMEF22 PRAMEF19 DYNC2I1 LAMC2 PRAMEF18 AR KHSRP DACH2 MICAL2 SLITRK5 PTCH2 ZFYVE26	3.70e-07	247	195	16	MP:0000538
MousePheno	enlarged urinary bladder	BTF3 PRAMEF22 PRAMEF19 DYNC2I1 PRAMEF18 DACH2 MICAL2 PTCH2 ZFYVE26	3.51e-05	116	195	9	MP:0011874
MousePheno	decreased large unstained cell number	PPM1M DYRK2 DYRK1B PKN1	4.44e-05	15	195	4	MP:0012361
Domain	L_dom-like	PODNL1 LRRC3C ERBB3 CARMIL3 LRRC32 LGR4 SLIT2 PXDN AMIGO3 LRRC73 GP5 NLRP5 LRRC8E LRFN1 PRAMEF22 PRAMEF19 CARMIL1 PRAMEF18 LGR5 LGI4 LRRC46 IGFALS LGI2 NISCH SLIT1 SLITRK5 PODN SCRIB LRRN4 LRRC23	3.45e-17	328	241	30	IPR032675
Domain	-	PODNL1 LRRC3C CARMIL3 LRRC32 LGR4 SLIT2 PXDN AMIGO3 LRRC73 GP5 NLRP5 LRRC8E LRFN1 PRAMEF22 PRAMEF19 CARMIL1 PRAMEF18 LGR5 LGI4 LRRC46 IGFALS LGI2 NISCH SLIT1 SLITRK5 PODN SCRIB LRRN4 LRRC23	1.68e-16	321	241	29	3.80.10.10
Domain	Leu-rich_rpt	PODNL1 LRRC3C CARMIL3 LRRC32 LGR4 SLIT2 PXDN AMIGO3 GP5 NLRP5 LRRC8E LRFN1 CARMIL1 LGR5 LGI4 LRRC46 IGFALS LGI2 NISCH SLIT1 SLITRK5 PODN SCRIB LRRN4 LRRC23	1.42e-14	271	241	25	IPR001611
Domain	LRR_TYP	PODNL1 LRRC3C LRRC32 LGR4 SLIT2 PXDN AMIGO3 GP5 LRRC8E LRFN1 LGR5 LGI4 LRRC46 IGFALS LGI2 SLIT1 SLITRK5 PODN SCRIB LRRN4	1.52e-13	177	241	20	SM00369
Domain	Leu-rich_rpt_typical-subtyp	PODNL1 LRRC3C LRRC32 LGR4 SLIT2 PXDN AMIGO3 GP5 LRRC8E LRFN1 LGR5 LGI4 LRRC46 IGFALS LGI2 SLIT1 SLITRK5 PODN SCRIB LRRN4	1.52e-13	177	241	20	IPR003591
Domain	LRR_8	PODNL1 LRRC3C LRRC32 LGR4 SLIT2 PXDN AMIGO3 GP5 LRRC8E LRFN1 LGR5 LGI4 IGFALS LGI2 SLIT1 SLITRK5 PODN SCRIB LRRN4	8.52e-13	171	241	19	PF13855
Domain	LRR_1	PODNL1 LRRC3C LRRC32 LGR4 SLIT2 PXDN AMIGO3 GP5 LRRC8E LGR5 LGI4 LRRC46 IGFALS LGI2 NISCH SLIT1 SLITRK5 PODN SCRIB LRRN4 LRRC23	9.44e-13	219	241	21	PF00560
Domain	LRR	PODNL1 LRRC3C LRRC32 LGR4 SLIT2 PXDN AMIGO3 GP5 LRRC8E LRFN1 LGR5 LGI4 LRRC46 IGFALS NISCH SLIT1 SLITRK5 PODN SCRIB LRRC23	1.68e-12	201	241	20	PS51450
Domain	LRRNT	PODNL1 LRRC3C LRRC32 LGR4 SLIT2 PXDN AMIGO3 GP5 LGR5 IGFALS SLIT1 SLITRK5 PODN	4.05e-10	98	241	13	IPR000372
Domain	LRRNT	PODNL1 LRRC3C LRRC32 LGR4 SLIT2 PXDN AMIGO3 GP5 LGR5 IGFALS SLIT1 SLITRK5 PODN	4.05e-10	98	241	13	SM00013
Domain	LRRNT	LRRC32 LGR4 SLIT2 AMIGO3 LGR5 IGFALS SLIT1 SLITRK5 PODN	2.31e-08	53	241	9	PF01462
Domain	Cys-rich_flank_reg_C	SLIT2 PXDN GP5 LRFN1 LGI4 IGFALS LGI2 SLIT1 SLITRK5 LRRN4	2.46e-07	90	241	10	IPR000483
Domain	LRRCT	SLIT2 PXDN GP5 LRFN1 LGI4 IGFALS LGI2 SLIT1 SLITRK5 LRRN4	2.46e-07	90	241	10	SM00082
Domain	FAD-bd	COQ6 KMO MICAL2	4.12e-05	6	241	3	IPR002938
Domain	FAD_binding_3	COQ6 KMO MICAL2	4.12e-05	6	241	3	PF01494
Domain	MKP	DUSP5 DUSP8 DUSP16	2.38e-04	10	241	3	IPR008343
Domain	CARMIL_C	CARMIL3 CARMIL1	4.93e-04	3	241	2	IPR031943
Domain	-	RASA4B RASA4	4.93e-04	3	241	2	4.10.1130.10
Domain	CARMIL_C	CARMIL3 CARMIL1	4.93e-04	3	241	2	PF16000
Domain	DUSP	DUSP5 DUSP8 DUSP14 DUSP16	6.47e-04	31	241	4	IPR024950
Domain	LRRCT	SLIT2 GP5 LGI4 SLIT1	7.32e-04	32	241	4	PF01463
Domain	RasGAP	GAPVD1 RASA4B RASA4	8.61e-04	15	241	3	PF00616
Domain	RAS_GTPASE_ACTIV_1	GAPVD1 RASA4B RASA4	8.61e-04	15	241	3	PS00509
Domain	RAS_GTPASE_ACTIV_2	GAPVD1 RASA4B RASA4	8.61e-04	15	241	3	PS50018
Domain	TYR_PHOSPHATASE_DUAL	DUSP5 DUSP8 DUSP14 DUSP16	9.25e-04	34	241	4	PS50054
Domain	Growth_fac_rcpt_	PCSK5 ERBB3 NOTCH2 LAMB2 LAMC2 CELSR1 HMCN1 SLIT1	9.64e-04	156	241	8	IPR009030
Domain	DSPc	DUSP5 DUSP8 DUSP14 DUSP16	1.03e-03	35	241	4	SM00195
Domain	TYR_PHOSPHATASE_DUAL_dom	DUSP5 DUSP8 DUSP14 DUSP16	1.03e-03	35	241	4	IPR020422
Domain	-	GAPVD1 RASA4B RASA4	1.05e-03	16	241	3	1.10.506.10
Pathway	REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES	CCP110 SFI1 TUBGCP2 TUBGCP5 CEP192 CEP164 AKAP9 CEP250	6.29e-06	81	172	8	M748
Pathway	REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES	CCP110 SFI1 TUBGCP2 TUBGCP5 CEP192 CEP164 AKAP9 CEP250	1.38e-05	90	172	8	MM14979
Pathway	REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES	CCP110 SFI1 TUBGCP2 TUBGCP5 CEP192 CEP164 AKAP9 CEP250	2.06e-05	95	172	8	M6729
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PCSK5 SPHK2 TMEM94 SFI1 TIAM2 C2CD2L FANCA TAOK2 PCNX2 PLEKHG1 JUN SH3TC1 FAM83F KLHL21 CSAD NFKB2 RIPOR1 MAFF ABCC10 PKN3 NOTCH2 LRRC8E ARHGEF19 KIAA0930 LRFN1 PLOD3 DUSP5 HECTD4 LAMB2 CEP192 HUWE1 TEP1 CELSR1 NISCH DUSP16 ZFYVE26 PKN1 NUP188 SYVN1 ARHGAP33	2.87e-17	1105	248	40	35748872
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TMEM94 C2CD2L PLEKHG1 PXDN STARD9 TBC1D1 RAB3GAP2 DLG3 RIPOR1 CHPF2 MTCL1 SYNE1 RALGAPB CEP192 AKAP9 LGI2 NISCH SLIT1 SCRIB SYVN1	1.85e-11	407	248	20	12693553
Pubmed	Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.	CCP110 SFI1 TUBGCP2 TUBGCP5 CEP192 CEP164 AKAP9 CEP250	2.40e-08	66	248	8	12221128
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	PCSK5 CCP110 TMEM94 SDR39U1 MAP3K3 DMXL1 TAOK2 PXDN GCLM RECQL4 HACE1 DLG3 RIPOR1 GNAS PKN3 DYRK2 CARMIL1 PRSS56 LAMB2 EMILIN1 ADAMTS10 ZBTB44 ZNF26 LTN1 WDR45B NUP188 CFAP46	2.06e-07	1215	248	27	15146197
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	TMEM94 CARMIL3 WRNIP1 TUBGCP2 TUBGCP5 DMXL1 CDAN1 SLIT2 FMN1 BTF3 KCNT1 CACNA1B KHSRP SLIT1 TNKS TP53BP1	3.76e-07	475	248	16	31040226
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	WRNIP1 LGR4 FASTKD5 TUBGCP2 CUL7 TUBGCP5 PGAM5 C2CD2L SLIT2 SH3TC1 KLHL21 CRNN CHPF2 NOTCH2 ANAPC4 PRSS56 TEP1 VANGL1 DROSHA LTN1 SMARCD3 SIGLEC1 NUP188 SCRIB ARHGAP33	5.16e-07	1116	248	25	31753913
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	GAPVD1 LEMD3 WRNIP1 MCM2 PRPF6 NSUN2 ANAPC4 PLOD3 HECTD4 HUWE1 PELP1 NISCH NUP188 SCRIB TP53BP1	7.55e-07	440	248	15	34244565
Pubmed	Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.	JUN DYNC2I1 CELSR1 VANGL1 PTCH2	1.03e-06	26	248	5	37228654
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	GAPVD1 LGR4 DHDDS SDR39U1 TIAM2 MAP3K3 FMN1 EXOC3L1 CPLANE1 GOLGB1 ZNF569 PRAMEF22 PRAMEF19 POLD2 CEP192 HUWE1 PRAMEF18 UBOX5 LTN1 NUP188 ACCSL KLHDC10 TP53BP1 SMAD2	1.08e-06	1084	248	24	11544199
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	LEMD3 WRNIP1 GCLM MTCL1 GNAS POLD2 ISOC2 DROSHA ARMC5 LTN1 SCRIB	1.52e-06	242	248	11	34011540
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	LEMD3 TMEM94 MCM2 DLG3 GOLGA5 GOLGB1 NOTCH2 CARMIL1 RALGAPB ATP6V0D1 VANGL1 NISCH SCRIB SMAD2	2.37e-06	421	248	14	36976175
Pubmed	The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion.	CCP110 SFI1 CEP192 CEP164 AKAP9 CEP250	2.98e-06	56	248	6	11076968
Pubmed	The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation.	CCP110 SFI1 CEP192 CEP164 AKAP9 CEP250	3.31e-06	57	248	6	16462731
Pubmed	Emergent growth cone responses to combinations of Slit1 and Netrin 1 in thalamocortical axon topography.	SEMA3A SLIT2 SLIT1	3.54e-06	5	248	3	22000108
Pubmed	Duplication and positive selection among hominin-specific PRAME genes.	PRAMEF22 PRAMEF19 PRAMEF18	3.54e-06	5	248	3	16159394
Pubmed	Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation.	CCP110 SFI1 CEP192 CEP164 AKAP9 CEP250	3.67e-06	58	248	6	12852856
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	PRPS2 LEMD3 TUBGCP2 RIPOR1 HEATR5B PKN3 KIF22 KIAA0930 LRFN1 VANGL1 SLITRK5 WDR45B SMAD2	3.79e-06	378	248	13	34315543
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CCP110 GAPVD1 MAP3K3 PLEKHG1 STARD9 TBC1D1 RAB3GAP2 MTCL1 GNAS GOLGB1 NOTCH2 DYRK2 KIAA0930 CARMIL1 RALGAPB CEP192 PTPN21 AKAP9 DYRK1B SCRIB	4.38e-06	861	248	20	36931259
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	CCP110 GAPVD1 TUBGCP2 CUL7 PGAM5 PLEKHG1 TBC1D1 ALDH18A1 MTCL1 NOTCH2 KIAA0930 RALGAPB CEP192 AKAP9	4.60e-06	446	248	14	24255178
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	GAPVD1 LEMD3 WRNIP1 FASTKD5 TUBGCP2 NSUN2 FANCA TAOK2 SLIT2 PXDN MOGS COG1 RAB3GAP2 CHPF2 HEATR5B DYNC2H1 HUWE1 ATF6 NISCH NUP188 SCRIB	4.72e-06	942	248	21	31073040
Pubmed	Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.	CCP110 SFI1 CEP192 CEP164 AKAP9 CEP250	4.95e-06	61	248	6	7790358
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TRAF3 CENPF ARMCX4 PGAM5 TAOK2 DLG3 MTCL1 KCNT1 GOLGB1 LRFN1 SYNE1 HECTD4 HUWE1 KHSRP AKAP9 PELP1 NISCH PKN1 TNKS SCRIB TP53BP1	6.61e-06	963	248	21	28671696
Pubmed	Cloning MafF by recognition site screening with the NFE2 tandem repeat of HS2: analysis of its role in globin and GCSl genes regulation.	JUN MOGS MAFF	7.05e-06	6	248	3	12490281
Pubmed	Epidermal wound repair is regulated by the planar cell polarity signaling pathway.	ARHGEF19 CELSR1 SCRIB	7.05e-06	6	248	3	20643356
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	GAPVD1 TRAF3 LEMD3 WRNIP1 MCM2 PGAM5 GNAS PLOD3 DUSP5 DUSP14 LAMB2 HUWE1 PTPN21 KHSRP WDR97 VANGL1 DUSP16 LTN1 TNKS NUP188 SMAD2	7.84e-06	974	248	21	28675297
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	PRPS2 HFE ERBB3 LEMD3 LGR4 COG1 ANGPT4 GOLGA5 PRPF39 GOLGB1 ABCC10 NOTCH2 KIAA0930 LRFN1 DYNC2H1 COQ6 HUWE1 SCARA5 ABCB8 LTN1 PKN1 NUP188	8.72e-06	1061	248	22	33845483
Pubmed	Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves.	SLIT2 HES1 NOTCH2 SLIT1	8.99e-06	19	248	4	25691540
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PCNX2 PXDN SH3TC1 TBC1D1 LMLN TTC12 OSBPL9 RIPOR1 GNAS GOLGB1 NOTCH2 CARMIL1 PCDH11Y RALGAPB HECTD4 DYNC2I1 SRCIN1 CEP192 HUWE1 TEP1 ATP10A AR ATF6 MICAL2 WDR45B PKN1 PCDH1	9.39e-06	1489	248	27	28611215
Pubmed	Flattop regulates basal body docking and positioning in mono- and multiciliated cells.	DLG3 CELSR1 VANGL1	1.23e-05	7	248	3	25296022
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	HFE SLC39A1 LEMD3 LGR4 DMXL1 FANCA SEMA3A PXDN MOGS OSBPL9 CHPF2 GOLGA5 NOTCH2 PLOD3 LAMB2 KHSRP ATF6 CELSR1 MICAL2 LTN1 SLITRK5 SCRIB SMAD2	1.92e-05	1201	248	23	35696571
Pubmed	Probing nuclear pore complex architecture with proximity-dependent biotinylation.	LEMD3 FMN1 GOLGB1 SYNE1 CEP250 NUP188	1.92e-05	77	248	6	24927568
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	GAPVD1 LEMD3 COG1 STARD9 BTF3 OSBPL9 GOLGA5 GOLGB1 NOTCH2 HUWE1 VANGL1 NISCH SCRIB	2.35e-05	449	248	13	31732153
Pubmed	Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss.	GCLM DUSP5 DUSP8 DUSP14 DUSP16	2.36e-05	48	248	5	30938680
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	PXDN CHPF2 CHST7 TRHDE PLOD3 LAMB2 ATF6 SCARA5	2.50e-05	164	248	8	32409323
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	CUL7 SPTBN5 NFKB2 HACE1 IL17RA SYNE1 DUSP5 TEP1 PKN1	2.54e-05	214	248	9	22199357
Pubmed	Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes.	NPHS1 VANGL1 SCRIB	2.92e-05	9	248	3	20534871
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	ERBB3 CENPF LEMD3 MCM2 FASTKD5 TUBGCP2 CDAN1 ANAPC4 HUWE1 KHSRP AKAP9 TP53BP1	3.12e-05	396	248	12	26687479
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	INPP1 NSUN2 PLEKHG1 KLHL21 OSBPL9 ALDH18A1 DLG3 AGAP4 ATG16L2 PRAMEF22 PRAMEF19 CARMIL1 DUSP5 RALGAPB MAU2 PRAMEF18 AKAP9 USHBP1 VANGL1 CEP250 AGAP7P POLG2 LRRC23	3.23e-05	1242	248	23	30973865
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CARMIL3 SH3TC1 ABCC10 ATG16L2 ARMC5 SIGLEC1	3.38e-05	85	248	6	15449545
Pubmed	Cytoplasmic localization of GRHL3 upon epidermal differentiation triggers cell shape change for epithelial morphogenesis.	ARHGEF19 CELSR1 SCRIB	4.14e-05	10	248	3	30283008
Pubmed	Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion.	ERBB3 PKN3 PKN1	4.14e-05	10	248	3	26774483
Pubmed	The protein interaction landscape of the human CMGC kinase group.	CCP110 TMEM94 FASTKD5 PRPF6 CUL7 JUN DYRK2 DUSP8 HUWE1 AKAP9 RASA4 VANGL1 DROSHA DYRK1B NUP188 SCRIB	4.51e-05	695	248	16	23602568
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	NLRP5 PRAMEF22 PRAMEF19 PRAMEF18	4.52e-05	28	248	4	25089626
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	GAPVD1 WRNIP1 CUL7 JUN SH3TC1 NFKB2 RECQL4 PRPF39 NOTCH2 KIF22 HUWE1 KHSRP ATF6 PELP1 NISCH SCRIB TP53BP1 SMAD2	4.97e-05	857	248	18	25609649
Pubmed	Actin stimulates reduction of the MICAL-2 monooxygenase domain.	IL17RA MICAL2	5.06e-05	2	248	2	23927065
Pubmed	A Structure-Activity Relationship Study of Bis-Benzamides as Inhibitors of Androgen Receptor-Coactivator Interaction.	AR PELP1	5.06e-05	2	248	2	31370197
Pubmed	Can defects in transferrin receptor 2 and hereditary hemochromatosis genes account for iron overload in HbH disease?	HFE TFR2	5.06e-05	2	248	2	12667993
Pubmed	Human HS1BP3 induces cell apoptosis and activates AP-1.	JUN HS1BP3	5.06e-05	2	248	2	21699750
Pubmed	Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region.	LGR4 LGR5	5.06e-05	2	248	2	9849958
Pubmed	Androgenic induction of prostate-specific antigen gene is repressed by protein-protein interaction between the androgen receptor and AP-1/c-Jun in the human prostate cancer cell line LNCaP.	JUN AR	5.06e-05	2	248	2	9211894
Pubmed	Analysis of HFE and TFR2 gene mutations in patients with acute leukemia.	HFE TFR2	5.06e-05	2	248	2	15863206
Pubmed	Calcium-Inducible MAPK/AP-1 Signaling Drives Semaphorin 3A Expression in Normal Human Epidermal Keratinocytes.	SEMA3A JUN	5.06e-05	2	248	2	31945349
Pubmed	Critical role for iron accumulation in the pathogenesis of fibrotic lung disease.	HFE TFR2	5.06e-05	2	248	2	32083318
Pubmed	A novel inducible transactivation domain in the androgen receptor: implications for PRK in prostate cancer.	AR PKN1	5.06e-05	2	248	2	12514133
Pubmed	Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice.	HFE TFR2	5.06e-05	2	248	2	22383097
Pubmed	Cell-lineage specificity and role of AP-1 in the prostate fibroblast androgen receptor cistrome.	JUN AR	5.06e-05	2	248	2	27634452
Pubmed	In situ proximity ligation assays indicate that hemochromatosis proteins Hfe and transferrin receptor 2 (Tfr2) do not interact.	HFE TFR2	5.06e-05	2	248	2	24155934
Pubmed	A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis.	HFE TFR2	5.06e-05	2	248	2	21173098
Pubmed	Slit1 and slit2 proteins control the development of the lateral olfactory tract.	SLIT2 SLIT1	5.06e-05	2	248	2	12097499
Pubmed	Prevalence of HFE and TFR2 gene mutation in 118 Ligurian rheumatic patients.	HFE TFR2	5.06e-05	2	248	2	15785438
Pubmed	Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling.	TRAF3 IL17RA	5.06e-05	2	248	2	21078888
Pubmed	CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.	RASA4B RASA4	5.06e-05	2	248	2	11448776
Pubmed	Loss of Hepatic Leucine-Rich Repeat-Containing G-Protein Coupled Receptors 4 and 5 Promotes Nonalcoholic Fatty Liver Disease.	LGR4 LGR5	5.06e-05	2	248	2	36410420
Pubmed	Lack of Hfe and TfR2 in Macrophages Impairs Iron Metabolism in the Spleen and the Bone Marrow.	HFE TFR2	5.06e-05	2	248	2	39273097
Pubmed	Analysis of HFE and TFR2 mutations in selected blood donors with biochemical parameters of iron overload.	HFE TFR2	5.06e-05	2	248	2	12681966
Pubmed	Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis.	HFE TFR2	5.06e-05	2	248	2	10681454
Pubmed	Positive epigenetic regulation loop between AR and NSUN2 promotes prostate cancer progression.	NSUN2 AR	5.06e-05	2	248	2	36169095
Pubmed	Human platelets express hemochromatosis protein (HFE) and transferrin receptor 2.	HFE TFR2	5.06e-05	2	248	2	12656741
Pubmed	Hemochromatosis gene sequence deviations in German patients with porphyria cutanea tarda.	HFE TFR2	5.06e-05	2	248	2	17298224
Pubmed	Identification of the functional domains of ANT-1, a novel coactivator of the androgen receptor.	PRPF6 AR	5.06e-05	2	248	2	16414017
Pubmed	1-Methyl-4-phenyl-pyridinium ion-induced oxidative stress, c-Jun phosphorylation and DNA fragmentation factor-45 cleavage in SK-N-SH cells are averted by selegiline.	DFFA JUN	5.06e-05	2	248	2	18805449
Pubmed	Androgen receptor transcriptional activity is required for heregulin-1β-mediated nuclear localization of the HER3/ErbB3 receptor tyrosine kinase.	ERBB3 AR	5.06e-05	2	248	2	37380074
Pubmed	AKAP9 is essential for spermatogenesis and sertoli cell maturation in mice.	AKAP9 CCNB1IP1	5.06e-05	2	248	2	23608191
Pubmed	Permissive corridor and diffusible gradients direct medial ganglionic eminence cell migration to the neocortex.	SLIT2 SLIT1	5.06e-05	2	248	2	12515855
Pubmed	Mutations in the planar cell polarity genes CELSR1 and SCRIB are associated with the severe neural tube defect craniorachischisis.	CELSR1 SCRIB	5.06e-05	2	248	2	22095531
Pubmed	High prevalence of HFE gene mutations in patients with porphyria cutanea tarda in the Czech Republic.	HFE TFR2	5.06e-05	2	248	2	18565178
Pubmed	Slit proteins: molecular guidance cues for cells ranging from neurons to leukocytes.	SLIT2 SLIT1	5.06e-05	2	248	2	12200164
Pubmed	Aberrant activation of the androgen receptor by NF-kappaB2/p52 in prostate cancer cells.	NFKB2 AR	5.06e-05	2	248	2	20388792
Pubmed	c-Jun can mediate androgen receptor-induced transactivation.	JUN AR	5.06e-05	2	248	2	8798722
Pubmed	Directional guidance of neuronal migration in the olfactory system by the protein Slit.	SLIT2 SLIT1	5.06e-05	2	248	2	10432110
Pubmed	Transcriptional activity of c-Jun is critical for the suppression of AR function.	JUN AR	5.06e-05	2	248	2	23523566
Pubmed	Hepatic iron deposition does not predict extrahepatic iron loading in mouse models of hereditary hemochromatosis.	HFE TFR2	5.06e-05	2	248	2	22858058
Pubmed	New mutations in DYNC2H1 and WDR60 genes revealed by whole-exome sequencing in two unrelated Sardinian families with Jeune asphyxiating thoracic dystrophy.	DYNC2H1 DYNC2I1	5.06e-05	2	248	2	26874042
Pubmed	Steerable-filter based quantification of axonal populations at the developing optic chiasm reveal significant defects in Slit2(-/-) as well as Slit1(-/-)Slit2(-/-) embryos.	SLIT2 SLIT1	5.06e-05	2	248	2	23320558
Pubmed	Rescue of TRAF3-null mice by p100 NF-kappa B deficiency.	TRAF3 NFKB2	5.06e-05	2	248	2	17015635
Pubmed	Involvement of α₂-adrenoceptors, imidazoline, and endothelin-A receptors in the effect of agmatine on morphine and oxycodone-induced hypothermia in mice.	EDNRA NISCH	5.06e-05	2	248	2	22681550
Pubmed	A role for the Golgi matrix protein giantin in ciliogenesis through control of the localization of dynein-2.	GOLGB1 DYNC2H1	5.06e-05	2	248	2	24046448
Pubmed	An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.	RASA4B RASA4	5.06e-05	2	248	2	16041389
Pubmed	Gene co-expression networks shed light into diseases of brain iron accumulation.	HFE TFR2	5.06e-05	2	248	2	26707700
Pubmed	Splicing factor PRPF6 upregulates oncogenic androgen receptor signaling pathway in hepatocellular carcinoma.	PRPF6 AR	5.06e-05	2	248	2	32745318
Pubmed	Blunted hepcidin response to inflammation in the absence of Hfe and transferrin receptor 2.	HFE TFR2	5.06e-05	2	248	2	21245482
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	EFCAB5 CCP110 PGAM5 SLIT2 GOLGB1 DNHD1 SYNE1 PELP1 CEP250	5.09e-05	234	248	9	36243803
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	GAPVD1 CENPF MCM2 PRPF6 CUL7 NSUN2 PGAM5 SLIT2 GNAS HEATR5B GOLGB1 KIF22 SYNE1 LAMB2 HUWE1 KHSRP PELP1 VANGL1 NUP188 SCRIB	5.20e-05	1024	248	20	24711643
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	WRNIP1 SEMA3A SLIT2 NOTCH2 RC3H2 DYNC2H1 WNT11 HUWE1 KHSRP ATP6V0D1 SLIT1	5.90e-05	358	248	11	32460013
Pubmed	Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells.	MAP3K3 JUN DUSP5 DUSP8	5.98e-05	30	248	4	17699753
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	TRAF3 LGR4 MCM2 PXDN MOGS GCLM BTF3 ALDH18A1 MTCL1 GNAS NOTCH2 KIF22 PLOD3 POLD2 COQ6 ATF6 ATP6V0D1 PELP1 VANGL1 NUP188 KLHDC10 TP53BP1 SMAD2	6.23e-05	1297	248	23	33545068
Pubmed	Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.	TRAF3 DLG3 KLHL22 ZBTB44 ARMC5 SCRIB SYVN1	6.31e-05	138	248	7	28786561
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	JUN GNAS CACNA1B MTERF4 PELP1 LTN1 TP53BP1 SMAD2	7.37e-05	191	248	8	20195357
Pubmed	Perivascular cells support folliculogenesis in the developing ovary.	HES1 NOTCH2 LGR5	7.51e-05	12	248	3	36194632
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	CENPF LEMD3 FASTKD5 ARMCX4 CUL7 TRMT2B PGAM5 C2CD2L SPTBN5 RAB3GAP2 OSBPL9 GNAS GOLGA5 FASTKD3 GOLGB1 SYNE1 MIS18A DYNC2I1 HUWE1 ATF6 AKAP9 VANGL1 NISCH NUP188 MMUT	7.66e-05	1496	248	25	32877691
Interaction	TOP3B interactions	PCSK5 SPHK2 CENPF TMEM94 SFI1 TIAM2 C2CD2L FANCA TAOK2 PCNX2 PLEKHG1 JUN MOGS SH3TC1 FAM83F KLHL21 CSAD NFKB2 RIPOR1 MAFF GNAS ABCC10 PKN3 NOTCH2 LRRC8E RC3H2 ARHGEF19 KIAA0930 LRFN1 PLOD3 DUSP5 HECTD4 LAMB2 CEP192 HUWE1 TEP1 CELSR1 PELP1 NISCH DUSP16 ZFYVE26 PKN1 NUP188 SYVN1 ARHGAP33 TP53BP1	1.45e-09	1470	241	46	int:TOP3B
Interaction	KHSRP interactions	TRAF3 LGR4 MCM2 CUL7 PGAM5 JUN BTF3 RECQL4 DUSP14 MAU2 HUWE1 AR KHSRP DROSHA TP53BP1	4.90e-06	308	241	15	int:KHSRP
Interaction	RHOQ interactions	LEMD3 CUL7 DMXL1 PLEKHG1 BTF3 OSBPL9 DLG3 GNAS GOLGA5 GOLGB1 NOTCH2 CARMIL1 RALGAPB LGR5 VANGL1 NISCH SLITRK5 SCRIB	6.77e-06	442	241	18	int:RHOQ
Interaction	UBE2L3 interactions	MCM2 RECQL4 HACE1 HERC6 CACNA1B DUSP8 HECTD4 HUWE1 UBOX5 LTN1 CCNB1IP1 TP53BP1	9.46e-06	211	241	12	int:UBE2L3
Cytoband	22q13.1-q13.2	APOBEC3G APOBEC3A	1.73e-04	4	248	2	22q13.1-q13.2
Cytoband	1p36.3-p36.2	DFFA SCNN1D	1.73e-04	4	248	2	1p36.3-p36.2
Cytoband	4p15.2	SLIT2 ANAPC4 LGI2	4.62e-04	28	248	3	4p15.2
GeneFamily	Ankyrin repeat domain containing	ANKRD34B USH1G NFKB2 HACE1 ANKRD61 TRPV3 AGAP4 NOTCH2 TNKS AGAP7P	3.49e-05	242	150	10	403
GeneFamily	MAP kinase phosphatases	DUSP5 DUSP8 DUSP16	8.80e-05	11	150	3	895
GeneFamily	PRAME family	PRAMEF22 PRAMEF19 PRAMEF18	9.97e-04	24	150	3	686
Coexpression	NABA_CORE_MATRISOME	PODNL1 SLIT2 PXDN LAMB2 LAMC2 LGI4 EMILIN1 IGFALS HMCN1 LGI2 SLIT1 PODN	1.12e-05	270	248	12	MM17057
Coexpression	NABA_CORE_MATRISOME	PODNL1 SLIT2 PXDN LAMB2 LAMC2 LGI4 EMILIN1 IGFALS HMCN1 LGI2 SLIT1 PODN	1.35e-05	275	248	12	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	SLIT2 PXDN LAMB2 LAMC2 LGI4 EMILIN1 IGFALS HMCN1 LGI2 SLIT1	1.51e-05	191	248	10	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	SLIT2 PXDN LAMB2 LAMC2 LGI4 EMILIN1 IGFALS HMCN1 LGI2 SLIT1	1.88e-05	196	248	10	M3008
Coexpression	GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_UP	TRAF3 MAP3K3 KLHL21 GPSM2 DUSP5 WNT11 XRCC3 ZBTB7B POLG2 TP53BP1	1.97e-05	197	248	10	M7670
Coexpression	GSE26030_TH1_VS_TH17_RESTIMULATED_DAY5_POST_POLARIZATION_DN	ERBB3 INPP1 MCM2 C2CD2L ALDH18A1 ZNF569 KHSRP NISCH DUSP16 SCRIB	2.24e-05	200	248	10	M8574
Coexpression	GSE22935_WT_VS_MYD88_KO_MACROPHAGE_24H_MBOVIS_BCG_STIM_UP	WRNIP1 MCM2 RAB3GAP2 RIPOR1 CARMIL1 MIS18A EMILIN1 WDR45B CCNB1IP1 TP53BP1	2.24e-05	200	248	10	M7749
Coexpression	GSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN	JUN MOGS SH3TC1 GCLM MAFF RC3H2 CARMIL1 DUSP5 RALGAPB SCRIB	2.24e-05	200	248	10	M8986
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LMLN CPLANE1 DYNC2H1 SYNE1 DYNC2I1 SRCIN1 LRRC9 AKAP9 CFAP74 CFAP46	1.63e-07	197	247	10	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LMLN CPLANE1 GP5 DYNC2H1 DYNC2I1 LRRC9 CFAP74 ARHGAP33 CFAP46	4.56e-07	169	247	9	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 GNAS MYO18B VSTM2B ATP10A EDNRA LGI2 MICAL2	4.79e-07	170	247	9	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 GNAS MYO18B VSTM2B ATP10A EDNRA LGI2 MICAL2	4.79e-07	170	247	9	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 GNAS MYO18B VSTM2B ATP10A EDNRA LGI2 MICAL2	4.79e-07	170	247	9	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 LGI4 ATP10A EMILIN1 EDNRA LGI2 MICAL2 SMARCD3	5.55e-07	173	247	9	901b8e6909c1f3849906fad9cee17b8f0bab050d
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 LGI4 ATP10A EMILIN1 EDNRA LGI2 MICAL2 SMARCD3	5.55e-07	173	247	9	fc2602b2ce051cd4c33957d7e3d041ff8a529883
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	PCSK5 LRRC32 SLIT2 SH3TC1 ADAMTS10 USHBP1 NISCH PTCH2 PODN	1.11e-06	188	247	9	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL3 KIF12 TAOK2 JUN GOLGB1 HUWE1 EMILIN1 IGFALS NISCH	1.44e-06	194	247	9	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC32 PLEKHG1 PXDN EXOC3L1 HES1 CHST7 EMILIN1 HMCN1 USHBP1	1.50e-06	195	247	9	12ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	PCSK5 LGR4 PCNX2 SLIT2 PXDN OSBPL9 CARMIL1 SCARA5 PODN	1.50e-06	195	247	9	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EFCAB5 CENPF C2CD2L TAOK2 LOXL3 DUSP5 KMO ARHGAP33 CFAP46	1.78e-06	199	247	9	6dc446a5d183b01bdf227e45bd88d0b3d8b1c56a
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLIT2 GPSM2 TRHDE DYNC2H1 SYNE1 EMILIN1 EDNRA AKAP9 SLITRK5	1.85e-06	200	247	9	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 GNAS LGI4 EMILIN1 EDNRA LGI2 SMARCD3	3.51e-06	162	247	8	5d902bb31e691aea9749617cc88303c2448f24b8
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 GNAS LGI4 EMILIN1 EDNRA LGI2 SMARCD3	3.51e-06	162	247	8	c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 GNAS LGI4 EMILIN1 EDNRA LGI2 SMARCD3	3.51e-06	162	247	8	f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCell	facs-Spleen-nan-24m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HFE CENPF GCLM GP5 DUSP8 ICAM4 VANGL1 CCDC74A	4.40e-06	167	247	8	16bb7293fc8ca582b7cb4450917aff07b34fc70a
ToppCell	facs-Spleen-nan-24m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HFE CENPF GCLM GP5 DUSP8 ICAM4 VANGL1 CCDC74A	4.40e-06	167	247	8	515988c7035c550a2f072430d9d7027869593d17
ToppCell	facs-Spleen-nan-24m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HFE CENPF GCLM GP5 DUSP8 ICAM4 VANGL1 CCDC74A	4.40e-06	167	247	8	f12d00e6c600b0bba3e4e1b1c80b791e095de931
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	C2CD2L FAM83F PRR14L GOLGA5 HEATR5B AGAP4 MAU2 CCDC144A	4.60e-06	168	247	8	8697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	FASTKD5 ZNF569 CARMIL1 UBOX5 EMILIN1 VANGL1 ZFYVE26 SCRIB	4.60e-06	168	247	8	8459d0a1bf6d4b5c83001097331f8b78fceb9305
ToppCell	BAL-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	SPHK2 CDAN1 STARD9 RASA4B CEP192 ZNF26 CARF CCDC144A	7.33e-06	179	247	8	68511e87b12b8253de7771e5ccfc5869248b8450
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_4\|Classical_Monocyte / Disease condition and Cell class	TRAF3 FANCA PCNX2 KLHL21 PLOD3 DUSP5 ZNF26 TTC31	7.33e-06	179	247	8	9d51318ac198a8801bd5c7031ebf2b0c74ffeeb6
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_4\|COVID-19_Convalescent / Disease condition and Cell class	TRAF3 FANCA PCNX2 KLHL21 PLOD3 DUSP5 ZNF26 TTC31	7.33e-06	179	247	8	366e4a31db9e80fd1770ac9f1ae148fefeb9f7df
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ERBB3 KIF12 CYP2W1 ARHGEF19 LGR5 CELSR1 WDR97 CCDC144A	9.33e-06	185	247	8	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B1\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	SEMA3A PLEKHG1 AMIGO3 EDNRA HMCN1 SLIT1	9.58e-06	88	247	6	1ca0e16981e88030987412e12838a9797b97b9c9
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	PCSK5 LGR4 PCNX2 SLIT2 PXDN CARMIL1 SCARA5 PODN	1.01e-05	187	247	8	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STARD9 ANGPT4 KCNT1 LGI4 ATP10A EDNRA DACH2 MICAL2	1.01e-05	187	247	8	48bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STARD9 ANGPT4 KCNT1 LGI4 ATP10A EDNRA DACH2 MICAL2	1.01e-05	187	247	8	958402fcc78f4c7a7d13d659d776f3817137975f
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LOXL3 WNT11 LGI4 LGI2 DACH2 VANGL1 SCARA5 PTCH2	1.01e-05	187	247	8	fa8f221b4c2df61eadaa9c77e4cf45848b00330b
ToppCell	CV-Severe-3\|Severe / Virus stimulation, Condition and Cluster	CARMIL3 APOBEC3G MCM2 JUN RECQL4 FES EMILIN1 SMARCD3	1.01e-05	187	247	8	68cb43a73945f5e252530da25613f6b3f484b4d5
ToppCell	droplet-Spleen-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF GCLM ICAM4 DYNC2I1 TFR2 USHBP1 VANGL1 PODN	1.05e-05	188	247	8	1a3f95b4fd7611c634666761ddf21f1e58e56af8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 ANGPT4 MYO18B LGI4 ATP10A EDNRA MICAL2	1.09e-05	189	247	8	127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 ANGPT4 MYO18B LGI4 ATP10A EDNRA MICAL2	1.09e-05	189	247	8	2cfb4d12f75678d1619f4743838a0e954bd57761
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PCSK5 LGR4 PLEKHG1 MTCL1 CACNA1B WNT11 PSTPIP1 DACH2	1.09e-05	189	247	8	0abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 MYO18B CARMIL1 ATP10A EDNRA LGI2 MICAL2	1.22e-05	192	247	8	bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCell	Ciliated-cil-3\|World / Class top	FANCA CRNN DYNC2H1 SYNE1 WNT11 DYNC2I1 CFAP74 LRRC23	1.22e-05	192	247	8	4989ebb8812b8af1870599acd932849122c05a29
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 MYO18B CARMIL1 ATP10A EDNRA LGI2 MICAL2	1.22e-05	192	247	8	b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL3 KIF12 TAOK2 JUN GOLGB1 EMILIN1 IGFALS NISCH	1.27e-05	193	247	8	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL3 KIF12 TAOK2 JUN GOLGB1 EMILIN1 IGFALS NISCH	1.32e-05	194	247	8	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 MYO18B LGI4 ATP10A EDNRA LGI2 MICAL2	1.32e-05	194	247	8	5c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 MYO18B LGI4 ATP10A EDNRA LGI2 MICAL2	1.32e-05	194	247	8	ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell	moderate-Epithelial-FOXN4+\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PRPS2 CCP110 CENPF CPLANE1 DYNC2H1 POLD2 CCDC74A CFAP46	1.32e-05	194	247	8	5dffa578149104dda33774361e9e77b227b5f1ce
ToppCell	COVID-19_Severe-Classical_Monocyte-cMono_4\|Classical_Monocyte / Disease condition and Cell class	APOBEC3A NFKB2 EXOC3L1 HES1 MAFF DUSP5 DUSP8 SIGLEC1	1.37e-05	195	247	8	1992a1673b7213e25f3c76ac77da35c57daceddd
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	LGR4 SLIT2 PXDN NOTCH2 DYNC2H1 CARMIL1 SCARA5 PODN	1.37e-05	195	247	8	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	COVID-19_Severe-Classical_Monocyte-cMono_4\|COVID-19_Severe / Disease condition and Cell class	APOBEC3A NFKB2 EXOC3L1 HES1 MAFF DUSP5 DUSP8 SIGLEC1	1.37e-05	195	247	8	787ea9f38ad8e2a836222ca97f4d927f7e79517d
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PCSK5 HPSE2 TRHDE SYNE1 LGR5 EMILIN1 HMCN1 PODN	1.47e-05	197	247	8	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG\|World / Primary Cells by Cluster	CENPF JUN TBC1D1 HES1 NOTCH2 LAMB2 CELSR1 VANGL1	1.47e-05	197	247	8	61749ccafeb938c310cff1de5ff924a1c794325a
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG-25\|World / Primary Cells by Cluster	CENPF JUN TBC1D1 HES1 NOTCH2 LAMB2 CELSR1 VANGL1	1.47e-05	197	247	8	9d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	LRRC32 APOBEC3G SH3TC1 NFKB2 IL17RA ZBTB7B LGI2 SYVN1	1.64e-05	200	247	8	25f4c051c2e869481f33c22ad54de97efac444ad
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	MCM2 PGAM5 STARD9 TBC1D1 HES1 LRRC73 NOTCH2 SCRIB	1.64e-05	200	247	8	98a994692440cb4f505b050276f0c8022c814a21
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial-Proteoglycan-expressing_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	LRRC32 APOBEC3G SH3TC1 NFKB2 IL17RA ZBTB7B LGI2 SYVN1	1.64e-05	200	247	8	da45a85a4667965b24ba824af871157af5b4cd19
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLEKHG1 SLIT2 TRHDE SYNE1 LGR5 EDNRA HMCN1 PODN	1.64e-05	200	247	8	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HPSE2 SLIT2 STARD9 TRHDE SYNE1 HMCN1 SCARA5 PODN	1.64e-05	200	247	8	3dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	MCM2 PGAM5 STARD9 TBC1D1 HES1 LRRC73 NOTCH2 SCRIB	1.64e-05	200	247	8	ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	EFCAB5 TIAM2 KIF22 DUSP5 ICAM4 SLIT1 LRRN4	3.55e-05	163	247	7	218b9ba099cb27aa91c6b73bf89b44895f5dddc3
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HFE FAM83F FMN1 NFKB2 MAFF SRCIN1 RASA4	3.99e-05	166	247	7	91eeb48680dd07ae4115afacdc0a8f6fa18885e5
ToppCell	VE-Treg-exh_CD4\|VE / Condition, Cell_class and T cell subcluster	CCP110 TRAF3 RASA4B HES1 CHST7 RC3H2 CEP164	4.15e-05	167	247	7	1036ac1ef9440612500137af9d1929672b077e4d
ToppCell	Ciliated_cells-A-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	CRNN LRRC73 SRCIN1 LRRC46 CCDC74A CFAP74 CFAP46	4.15e-05	167	247	7	edb722ee9b6ccd00fb038f702be8664020932659
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 SLIT2 KCNT1 MICAL2 SCARA5 SLITRK5 PODN	4.31e-05	168	247	7	4b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HFE TIAM2 LMLN HES1 IL17RA KIAA0930 DUSP16	4.64e-05	170	247	7	8e774af244cfe787fa0ea2b6be0c3c2d00bfe4fc
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HFE TIAM2 LMLN HES1 IL17RA KIAA0930 DUSP16	4.64e-05	170	247	7	f5140eb9313c0d1bb31f8a761d9c062c56733a61
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 SLIT2 KCNT1 MICAL2 SCARA5 SLITRK5 PODN	4.82e-05	171	247	7	5d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell	356C-Epithelial_cells-Epithelial-H_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PRPS2 TMEM94 INPP1 PPM1M MCM2 COQ6	5.08e-05	118	247	6	08bdf7bc3c9dcbc0f690658fe14e6cc4b9581698
ToppCell	356C-Epithelial_cells-Epithelial-H_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PRPS2 TMEM94 INPP1 PPM1M MCM2 COQ6	5.08e-05	118	247	6	3b077ad5c68c01b3fcc93f203cb130bb90705af9
ToppCell	CV-Mild-7\|Mild / Virus stimulation, Condition and Cluster	EFCAB5 CCP110 PLEKHG1 COG1 MAFF NOTCH2 PLOD3	5.18e-05	173	247	7	c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HPSE2 ARMCX4 KCNT1 CACNA1B VSTM2B LRRC9 RTL1	5.99e-05	177	247	7	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	Endothelial-Endothelial-C\|Endothelial / shred on cell class and cell subclass (v4)	PCSK5 ARMCX4 SDR39U1 FES RC3H2 SRCIN1 HMCN1	5.99e-05	177	247	7	b5b9278dfd76b1aacd88e5fe86e91a2c9b565f87
ToppCell	RV-11._Adipocyte\|RV / Chamber and Cluster_Paper	PCSK5 DHDDS HPSE2 SEMA3A CSAD GYG2 TRHDE	6.21e-05	178	247	7	278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_B\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	LRRC32 EXOC3L1 KIF22 MIS18A DUSP8 DACH2	6.41e-05	123	247	6	e0130010aa406d4e9d8f16ad32858c382277eeb2
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Myxofibrosarcoma-4\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	MAP3K3 CRNN CHST7 CARMIL1 USHBP1 SCARA5	6.41e-05	123	247	6	12b87d06e62f142e18424aae5c87454e78e713f0
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2H1 DYNC2I1 LRRC46 WDR97 CFAP74 LRRC23 CFAP46	6.43e-05	179	247	7	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	PND10-Immune-Immune_Myeloid-Dendritic-cDC1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCP110 CENPF PPM1M KMO PELP1 CARF POLG2	7.39e-05	183	247	7	ab38264daddccdf5ffb75ff2210b27423eca6bc0
ToppCell	PND10-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCP110 CENPF PPM1M KMO PELP1 CARF POLG2	7.39e-05	183	247	7	263bfa1d8a7314bc3156c735c403c3bab8ea4dac
ToppCell	PND10-Immune-Immune_Myeloid-Dendritic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCP110 CENPF PPM1M KMO PELP1 CARF POLG2	7.39e-05	183	247	7	e4911601dca2c0ecb448cdb6b222dedfc0c8bf6c
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EFCAB5 CENPF MCM2 LMLN RECQL4 LRRC46 CCDC74A	7.91e-05	185	247	7	47c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	CCP110 CPLANE1 CARMIL1 LAMC2 PTPN21 ATP10A LRRN4	7.91e-05	185	247	7	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	droplet-Liver-Npc-18m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAOK2 CDAN1 HES1 CHST7 LAMB2 LGR5 EMILIN1	8.18e-05	186	247	7	75258d88e23112fd1f0f7c71ef0366abb400d33e
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	INPP1 PLEKHG1 HES1 PKN3 PCDH11Y ATP10A HMCN1	8.46e-05	187	247	7	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF GCLM GPSM2 KIF22 ICAM4 TFR2 CCDC74A	8.46e-05	187	247	7	dceca7ae3dae96078cccc17a0d8a61b06fa6dffb
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Oligodendrocyte.Tnf.Igsf8-Ctps_(Ctps)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ERBB3 TTC23L ANGPT4 ANKRD61 LRRC8E	8.73e-05	81	247	5	4529c9b40330361d999a8532268e0ee935affd8d
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PCSK5 LGR4 HPSE2 MTCL1 WNT11 EMILIN1 DACH2	8.74e-05	188	247	7	c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CENPF TUBGCP5 GYG2 HES1 LRRC9 CELSR1 AKAP9	8.74e-05	188	247	7	0476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 LGI4 ATP10A EDNRA LGI2 MICAL2	9.04e-05	189	247	7	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PXDN SH3TC1 DYRK2 CARMIL1 RASA4 VANGL1 PCDH1	9.04e-05	189	247	7	09dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HPSE2 TBC1D1 LGI4 ATP10A EDNRA LGI2 MICAL2	9.04e-05	189	247	7	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STARD9 KCNT1 LGI4 ATP10A EDNRA DACH2 MICAL2	9.04e-05	189	247	7	fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC32 PLEKHG1 PXDN EXOC3L1 CHST7 EMILIN1 USHBP1	9.65e-05	191	247	7	1924af7d8b0a0b892e480a9fd6d874941b0c0b5d
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC32 PLEKHG1 PXDN EXOC3L1 CHST7 EMILIN1 USHBP1	9.65e-05	191	247	7	88f91e57a1409bdeb91e9bf47510a6fb998a1bf5
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	LGR4 SLIT2 STARD9 TRHDE DYNC2H1 CARMIL1 SCARA5	9.65e-05	191	247	7	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCLM RECQL4 KIF22 ICAM4 DYNC2I1 TFR2 CCDC74A	9.97e-05	192	247	7	a94f47a664a3c9d1b0250269674453309ab4bf95
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC32 ARMCX4 PLEKHG1 PXDN EXOC3L1 EMILIN1 USHBP1	9.97e-05	192	247	7	5890076929598e88fe9d59a4e4e858b446746ce9
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Nxph2_Sla\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SPTBN5 IL17RA NPHS1 SLIT1 PTCH2 PODN	1.03e-04	134	247	6	6d97fa07f55ae20c17b9d5262e893957cccc6dba
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	PCSK5 TMEM94 LGR4 SEMA3A RASA4B CPLANE1	1.03e-04	134	247	6	9e12aac8f42790c2f104dfd61c87aa99fc7925f1
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC32 ARMCX4 PLEKHG1 PXDN EXOC3L1 EMILIN1 USHBP1	1.03e-04	193	247	7	d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCell	(6)_Endothelial-C_(Capillary_Aerocyte_)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	SEMA3A PLEKHG1 PXDN EXOC3L1 HES1 PKN3 PCDH1	1.03e-04	193	247	7	f7f2dc6aff02d096a282835094d26d12b3b73e61
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC32 ARMCX4 PLEKHG1 PXDN EXOC3L1 EMILIN1 USHBP1	1.03e-04	193	247	7	4a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CENPF MCM2 FANCA RECQL4 MTCL1 XRCC3 DACH2	1.03e-04	193	247	7	bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DYNC2H1 SYNE1 DYNC2I1 LRRC46 CFAP74 LRRC23 CFAP46	1.03e-04	193	247	7	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	COVID-19-Endothelial_cells-Inflamed_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	LRRC32 PLEKHG1 PXDN EXOC3L1 SYNE1 DUSP5 PCDH1	1.03e-04	193	247	7	979ebefa527f86bebeea5d94e626ee6c1cc7d53b
Drug	chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A	HFE CCNP APOBEC3G TAOK2 BTF3 GYG2 MAFF HUWE1 EDNRA CEP250 NUP188 ARHGAP33	1.60e-06	196	246	12	5577_UP
Drug	Flunixin meglumine [42461-84-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A	HFE SPHK2 INPP1 TAOK2 PCNX2 ICAM4 PTPN21 XRCC3 UBOX5 ZBTB44 ATF6 DYRK1B	1.68e-06	197	246	12	3411_UP
Drug	Sulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; MCF7; HT_HG-U133A	TUBGCP5 TAOK2 JUN NFKB2 PRR14L CHST7 LAMB2 PTPN21 ATF6 CARF ARHGAP33 LRRC23	1.68e-06	197	246	12	1695_UP
Drug	metolachlor	DHDDS PCBD2 DYRK2 DUSP5 DUSP8 DUSP14 DUSP16 DYRK1B	5.06e-06	88	246	8	CID000004169
Drug	CP-690334-01 [459212-38-5]; Down 200; 10uM; MCF7; HT_HG-U133A	HFE PCNX2 SH3TC1 NFKB2 GYG2 RIPOR1 ICAM4 LAMC2 KHSRP PCDH1 LRRC23	8.64e-06	193	246	11	4380_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HG-U133A	ERBB3 LEMD3 FASTKD5 FANCA SLIT2 MTERF4 KMO ATF6 CFAP74 ZFYVE26 LRRC23	1.05e-05	197	246	11	381_DN
Drug	Tetracaone hydrochloride [136-47-0]; Up 200; 13.2uM; MCF7; HT_HG-U133A	HPSE2 SFI1 TAOK2 SPTBN5 NFKB2 GYG2 MAFF KIAA0930 MAU2 TFR2 PCDH1	1.05e-05	197	246	11	2888_UP
Drug	Azathioprine [446-86-6]; Down 200; 14.4uM; PC3; HG-U133A	SPHK2 CCNP C2CD2L TAOK2 DLG3 CHPF2 MAFF RALGAPB KMO TTC31 NUP188	1.15e-05	199	246	11	1945_DN
Drug	Hb H	HFE CDAN1 DLG3 GNAS TFR2 NISCH	1.26e-05	48	246	6	CID000466959
Drug	KU-2285	DHDDS EDNRA SIGLEC1	2.43e-05	6	246	3	CID000366729
Drug	Rimexolone [49697-38-3]; Down 200; 10.8uM; HL60; HT_HG-U133A	SFI1 C2CD2L JUN CSAD NFKB2 MAFF TRHDE DUSP5 SCRIB KLHDC10	3.34e-05	184	246	10	2955_DN
Drug	Naringenine [480-41-1]; Down 200; 14.6uM; MCF7; HT_HG-U133A	HFE TUBGCP2 TRMT2B JUN GYG2 PTPN21 MTERF4 KLHL22 TNKS NUP188	3.83e-05	187	246	10	3278_DN
Drug	Dicyclomine hydrochloride [67-92-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A	C2CD2L TAOK2 JUN NFKB2 MAFF DUSP5 LAMC2 MAU2 HUWE1 NUP188	4.01e-05	188	246	10	4405_UP
Drug	15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A	HFE CYP2W1 TAOK2 PCNX2 GYG2 GNAS WNT11 KHSRP KLHL22 CFAP74	4.79e-05	192	246	10	7489_UP
Drug	Azacyclonol [115-46-8]; Up 200; 15uM; MCF7; HT_HG-U133A	CUL7 JUN MAFF IL17RA CPLANE1 CEP164 EDNRA TFR2 AKAP9 ARHGAP33	5.23e-05	194	246	10	5398_UP
Drug	Etanidazole [22668-01-5]; Down 200; 18.6uM; MCF7; HT_HG-U133A	INPP1 PCNX2 KLHL21 RIPOR1 XRCC3 CEP164 EDNRA KLHL22 PCDH1 LRRC23	5.23e-05	194	246	10	6072_DN
Drug	Berberine chloride [633-65-8]; Up 200; 10.8uM; MCF7; HT_HG-U133A	HFE CENPF NFKB2 MAFF DYRK2 LAMC2 KMO KHSRP KLHL22 LRRC23	5.46e-05	195	246	10	2770_UP
Drug	Scopoletin [92-61-5]; Down 200; 20.8uM; MCF7; HT_HG-U133A	TUBGCP2 C2CD2L JUN KLHL21 RIPOR1 GOLGB1 NOTCH2 PTPN21 MTERF4 UBOX5	5.46e-05	195	246	10	6510_DN
Drug	0179445-0000 [211246-22-9]; Down 200; 1uM; MCF7; HT_HG-U133A	INPP1 SFI1 CUL7 SLIT2 TTC12 DUSP8 PTPN21 TEP1 UBOX5 ARHGAP33	5.70e-05	196	246	10	3633_DN
Drug	Guanadrel sulfate [22195-34-2]; Down 200; 7.6uM; PC3; HT_HG-U133A	TTC12 DLG3 DYRK2 DUSP8 LAMC2 PTPN21 MTERF4 CEP250 SLITRK5 LRRC23	5.95e-05	197	246	10	7396_DN
Drug	estradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A	HFE SPHK2 SLIT2 GYG2 RIPOR1 PRR14L PTPN21 TEP1 KLHL22 ZBTB44	5.95e-05	197	246	10	5238_DN
Drug	Gemfibrozil [25812-30-0]; Down 200; 16uM; MCF7; HT_HG-U133A	SPHK2 JUN SH3TC1 GYG2 ABCC10 AR CEP164 KLHL22 ARHGAP33 LRRC23	5.95e-05	197	246	10	2277_DN
Drug	Talampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A	CUL7 TAOK2 RAB3GAP2 RIPOR1 MAFF KIAA0930 TEP1 UBOX5 TFR2 SMARCD3	6.21e-05	198	246	10	3515_UP
Drug	2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; MCF7; HT_HG-U133A	HFE CENPF FANCA IL17RA DUSP8 CEP164 EDNRA KLHL22 PCDH1 ARHGAP33	6.21e-05	198	246	10	5422_UP
Drug	Clorgyline hydrochloride [17780-75-5]; Down 200; 13uM; MCF7; HT_HG-U133A	HFE CENPF SFI1 TTC12 CHPF2 PRR14L MTCL1 DYNC2H1 EDNRA MICAL2	6.21e-05	198	246	10	3219_DN
Drug	Tolfenamic acid [13710-19-5]; Up 200; 15.2uM; HL60; HG-U133A	HFE TUBGCP2 TRMT2B PXDN GPSM2 RALGAPB XRCC3 KHSRP ZBTB44 PKN1	6.21e-05	198	246	10	1437_UP
Drug	Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Down 200; 21uM; HL60; HT_HG-U133A	HFE APOBEC3G SFI1 CUL7 PCNX2 SPTBN5 UBOX5 KMO SLITRK5 ARHGAP33	6.21e-05	198	246	10	2999_DN
Drug	Fluocinonide [356-12-7]; Up 200; 8uM; MCF7; HT_HG-U133A	SPHK2 CCNP CUL7 PCNX2 MAFF UBOX5 ATP10A KMO TFR2 CEP250	6.48e-05	199	246	10	3839_UP
Drug	dopamine hydrochloride; Down 200; 1uM; MCF7; HG-U133A	CENPF CCNP C2CD2L CHPF2 LAMC2 CEP192 UBOX5 CELSR1 KLHDC10 TP53BP1	6.48e-05	199	246	10	491_DN
Drug	Sulmazole [73384-60-8]; Up 200; 14uM; HL60; HT_HG-U133A	SPHK2 APOBEC3G TAOK2 NFKB2 GYG2 RIPOR1 SYNE1 UBOX5 SMARCD3 NUP188	6.48e-05	199	246	10	2153_UP
Drug	Glycocholic acid [475-31-0]; Up 200; 8.6uM; HL60; HT_HG-U133A	APOBEC3G SFI1 FANCA SLIT2 NOTCH2 LAMB2 MAU2 XRCC3 TNKS NUP188	6.48e-05	199	246	10	2454_UP
Drug	Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	HFE TUBGCP2 RIPOR1 GNAS DUSP8 PTPN21 ATP10A EDNRA SIGLEC1 PCDH1	6.75e-05	200	246	10	6839_UP
Disease	Malignant neoplasm of breast	ERBB3 CENPF APOBEC3A SEMA3A JUN FAM83F EXOC3L1 HES1 FASTKD3 GOLGB1 NOTCH2 ZNF569 DYNC2H1 SYNE1 XRCC3 AR EDNRA AKAP9 NISCH ABCB8 ZFYVE26 KLHDC10 TP53BP1	1.48e-05	1074	232	23	C0006142
Disease	NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO	CELSR1 VANGL1 SCRIB	2.61e-05	8	232	3	C3891448
Disease	systolic blood pressure, self reported educational attainment	ANKRD34B SPSB2 LRRC23	5.53e-05	10	232	3	EFO_0004784, EFO_0006335
Disease	Caudal Dysgenesis Syndrome	PCSK5 VANGL1	6.16e-05	2	232	2	C1838569
Disease	Sacral defect and anterior sacral meningocele	PCSK5 VANGL1	6.16e-05	2	232	2	C1838568
Disease	ACTH-independent Cushing syndrome	GNAS ARMC5	6.16e-05	2	232	2	cv:CN294278
Disease	Lumbosacral agenesis	PCSK5 VANGL1	6.16e-05	2	232	2	C0431415
Disease	Cushing syndrome due to macronodular adrenal hyperplasia	GNAS ARMC5	6.16e-05	2	232	2	cv:C2062388
Disease	Acth-Independent Macronodular Adrenal Hyperplasia	GNAS ARMC5	1.84e-04	3	232	2	C1857451
Disease	Mammary Carcinoma, Human	ERBB3 CENPF APOBEC3A JUN HES1 NOTCH2 DYNC2H1 SYNE1 XRCC3 AR NISCH KLHDC10 TP53BP1	2.91e-04	525	232	13	C4704874
Disease	Mammary Neoplasms, Human	ERBB3 CENPF APOBEC3A JUN HES1 NOTCH2 DYNC2H1 SYNE1 XRCC3 AR NISCH KLHDC10 TP53BP1	2.91e-04	525	232	13	C1257931
Disease	Mammary Neoplasms	ERBB3 CENPF APOBEC3A JUN HES1 NOTCH2 DYNC2H1 SYNE1 XRCC3 AR NISCH KLHDC10 TP53BP1	3.01e-04	527	232	13	C1458155
Disease	Cushing syndrome	GNAS ARMC5	3.66e-04	4	232	2	cv:C0010481
Disease	Breast Carcinoma	ERBB3 CENPF APOBEC3A JUN HES1 NOTCH2 DYNC2H1 SYNE1 XRCC3 AR NISCH KLHDC10 TP53BP1	3.67e-04	538	232	13	C0678222
Disease	Short rib-polydactyly syndrome, Verma-Naumoff type	DYNC2H1 DYNC2I1	6.06e-04	5	232	2	C0432197
Disease	Familial thoracic aortic aneurysm and aortic dissection	PLOD3 EMILIN1 ADAMTS10 SMAD2	8.06e-04	53	232	4	C4707243
Disease	nephrotic syndrome (implicated_via_orthology)	GAPVD1 NPHS1 COQ6	8.60e-04	24	232	3	DOID:1184 (implicated_via_orthology)
Disease	VACTERL association (implicated_via_orthology)	PCSK5 DYNC2H1	9.04e-04	6	232	2	DOID:14679 (implicated_via_orthology)
Disease	brain disease (implicated_via_orthology)	TIAM2 DROSHA	9.04e-04	6	232	2	DOID:936 (implicated_via_orthology)
Disease	hemochromatosis (is_implicated_in)	HFE TFR2	9.04e-04	6	232	2	DOID:2352 (is_implicated_in)
Disease	Antithrombotic agent use measurement	FES HECTD4 EDNRA TNKS	9.28e-04	55	232	4	EFO_0009925
Disease	brain cancer (implicated_via_orthology)	GPSM2 HES1 NOTCH2	1.09e-03	26	232	3	DOID:1319 (implicated_via_orthology)
Disease	Hereditary hemochromatosis	HFE TFR2	1.26e-03	7	232	2	cv:C0392514
Disease	Sacral agenesis	PCSK5 VANGL1	1.26e-03	7	232	2	C0344490
Disease	Lead Poisoning	HFE XRCC3	1.26e-03	7	232	2	C0023176
Disease	central nervous system cancer (implicated_via_orthology)	HES1 NOTCH2	1.26e-03	7	232	2	DOID:3620 (implicated_via_orthology)
Disease	Ependymoblastoma	HES1 NOTCH2	1.67e-03	8	232	2	C0700367
Disease	Neuroectodermal Tumor, Primitive	HES1 NOTCH2	1.67e-03	8	232	2	C0206663
Disease	phenol sulfate measurement	PLEKHG1 MYO18B	1.67e-03	8	232	2	EFO_0021011
Disease	Cerebral Primitive Neuroectodermal Tumor	HES1 NOTCH2	1.67e-03	8	232	2	C0751675
Disease	Spongioblastoma	HES1 NOTCH2	1.67e-03	8	232	2	C0334584
Disease	Medulloepithelioma	HES1 NOTCH2	1.67e-03	8	232	2	C0334596
Disease	benign neoplasm (implicated_via_orthology)	DLG3 SCRIB	1.67e-03	8	232	2	DOID:0060072 (implicated_via_orthology)
Disease	Spastic Paraplegia	RAB3GAP2 HACE1	2.14e-03	9	232	2	C0037772
Disease	Polydactyly	CENPF CPLANE1 DYNC2H1 DYNC2I1 CEP164	2.36e-03	117	232	5	C0152427
Disease	diastolic blood pressure, alcohol drinking	PLEKHG1 FES HECTD4 SLIT1 TNKS	2.45e-03	118	232	5	EFO_0004329, EFO_0006336
Disease	cerebral palsy (implicated_via_orthology)	AGAP4 AGAP7P	2.66e-03	10	232	2	DOID:1969 (implicated_via_orthology)
Disease	polymeric immunoglobulin receptor measurement	CHPF2 SMARCD3	2.66e-03	10	232	2	EFO_0008267
Disease	Jeune thoracic dystrophy	DYNC2H1 DYNC2I1	3.23e-03	11	232	2	C0265275
Disease	systolic blood pressure, alcohol drinking	PLEKHG1 FES ABCC10 HECTD4 TNKS	3.48e-03	128	232	5	EFO_0004329, EFO_0006335
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	LEMD3 SYNE1	3.86e-03	12	232	2	DOID:11726 (implicated_via_orthology)
Disease	iron biomarker measurement, serum iron measurement	HFE TFR2	3.86e-03	12	232	2	EFO_0004461, EFO_0006332
Disease	AL amyloidosis	CHPF2 SMARCD3	3.86e-03	12	232	2	MONDO_0019438
Disease	Hereditary hemochromatosis	HFE TFR2	3.86e-03	12	232	2	C0392514
Disease	Hemochromatosis	HFE TFR2	3.86e-03	12	232	2	C0018995
Disease	matrix metalloproteinase measurement	MAFF DYNC2H1	4.53e-03	13	232	2	EFO_0004744
Disease	Short Rib-Polydactyly Syndrome	DYNC2H1 DYNC2I1	4.53e-03	13	232	2	C0036996
Disease	Mental Retardation, X-Linked Nonsyndromic	DLG3 HUWE1	4.53e-03	13	232	2	C3501611
Disease	pulmonary emphysema (implicated_via_orthology)	JUN EDNRA	4.53e-03	13	232	2	DOID:9675 (implicated_via_orthology)
Disease	Malignant Head and Neck Neoplasm	ERBB3 FANCA XRCC3	5.01e-03	44	232	3	C0278996
Disease	iron biomarker measurement, transferrin saturation measurement	HFE TFR2	5.26e-03	14	232	2	EFO_0004461, EFO_0006333
Disease	Saldino-Noonan Syndrome	DYNC2H1 DYNC2I1	5.26e-03	14	232	2	C0036069
Disease	Majewski Syndrome	DYNC2H1 DYNC2I1	5.26e-03	14	232	2	C0024507
Disease	obesity (is_implicated_in)	HFE GNAS NMB AR	5.84e-03	91	232	4	DOID:9970 (is_implicated_in)
Disease	nevus count, cutaneous melanoma	FANCA FMN1 NOTCH2 KIAA0930	5.84e-03	91	232	4	EFO_0000389, EFO_0004632
Disease	Down syndrome (implicated_via_orthology)	DYRK2 DYRK1B	6.04e-03	15	232	2	DOID:14250 (implicated_via_orthology)
Disease	Neoplasm of uncertain or unknown behavior of bladder	ERBB3 NOTCH2	6.04e-03	15	232	2	C0496930
Disease	liver volume	MAU2 TP53BP1	6.04e-03	15	232	2	EFO_0600048
Disease	Benign neoplasm of bladder	ERBB3 NOTCH2	6.04e-03	15	232	2	C0154017
Disease	Carcinoma in situ of bladder	ERBB3 NOTCH2	6.04e-03	15	232	2	C0154091
Disease	transferrin saturation measurement	HFE TFR2	6.87e-03	16	232	2	EFO_0006333
Disease	Colonic Neoplasms	MCM2 JUN HES1 LGR5 TP53BP1	7.16e-03	152	232	5	C0009375
Disease	mean arterial pressure, alcohol drinking	PLEKHG1 FES HECTD4 SLIT1	7.56e-03	98	232	4	EFO_0004329, EFO_0006340
Disease	Herpes Zoster	LRRC32 HACE1	7.74e-03	17	232	2	EFO_0006510

Protein segments in the cluster

Peptide	Gene	Start	Entry
LTSSTLSRRLQHLAL	USH1G	181	Q495M9
SLGHLSIQRAALVVL	VANGL1	266	Q8TAA9
IRNHEVLSVSNRAGL	TRHDE	706	Q9UKU6
LRRLRSHSSTQILGS	USHBP1	266	Q8N6Y0
LHSELAARQTQGRLL	nan	41	A4D1N5
QLTSRQGLSLEERRH	ACCSL	46	Q4AC99
DLQTAILLLAHGSRE	AGAP4	576	Q96P64
TLHSGLRRSLQNLLA	EXOC3L1	311	Q86VI1
NSSHALRQLRLTQLT	ERBB3	126	P21860
LNQLGADSLTSLRRL	BTF3	151	P20290
DRRSLLSEIQALHAQ	AKAP9	3086	Q99996
ERLLRQNAELTGHIS	AKAP9	3586	Q99996
VQGRVTSLSLSHDQL	ATG16L2	501	Q8NAA4
LRRHTDISQSVSNGL	ANAPC4	601	Q9UJX5
NILTIRLTAADHRQL	CTAG1A	131	P78358
RLTAADHRQLQLSIS	CTAG1A	136	P78358
QQGLRGLHLSSDRLQ	DUSP8	371	Q13202
GLHLSSDRLQDTNRL	DUSP8	376	Q13202
EHSQALSGRLRAILQ	APOBEC3A	181	P31941
EHSQDLSGRLRAILQ	APOBEC3G	366	Q9HC16
QLSADNRTLIIHGLQ	CEACAM20	301	Q6UY09
NRTLIIHGLQRNDTG	CEACAM20	306	Q6UY09
LLARARTLHLQTGNL	GCLM	11	P48507
RLHSVQGLLSLQDLQ	CFAP46	1846	Q8IYW2
VGNLHLLRLSQQDRS	CYP2W1	41	Q8TAV3
RQRHNTALLAATDLL	COQ6	416	Q9Y2Z9
LGRGSVASNRHLLQA	DUSP14	36	O95147
GLRVLRLSHNAIASL	IGFALS	291	P35858
SRHRELGERLLQNLT	ARMC5	616	Q96C12
RNGSLRIALSEHLKQ	EDNRA	286	P25101
GNRTHRILTDIQNSS	ANKRD61	131	A6NGH8
INTTESLRLNHELRG	ATF6	471	P18850
RELALRLQQTQSLHS	DFFA	291	O00273
ALQLVRALRSATQHT	CELSR1	2131	Q9NYQ6
HLRLLLSRGIQGQTQ	DNHD1	2421	Q96M86
LTLDLSSNRLGHISV	AMIGO3	186	Q86WK7
SLAHRLLDGAGSRLQ	CCNP	256	Q9H8S5
LAVRLTANITAGHLL	MT-ATP6	156	P00846
QELRHLKSLLEGSQR	CCDC74A	291	Q96AQ1
SLGVLQENARLLTHA	DACH2	186	Q96NX9
GRLSRGLSEHNALLQ	CACNA1B	2226	Q00975
NHERRLRSLTISASG	DMXL1	1366	Q9Y485
LRLHRSLVLSQESEG	CDAN1	721	Q8IWY9
LRNTHFRGVSLNLTR	DYRK1B	201	Q9Y463
QLAGLRLIRHLTITS	ARMCX4	2141	Q5H9R4
QSAIRLETNLHLLGA	ATP10A	846	O60312
HFLLNLTRSSRLLAG	ADAMTS10	86	Q9H324
NSLDEGRHLTLNLLS	RC3H2	1016	Q9HBD1
QSAQTLRAHLGALLS	RASA4	411	O43374
QSAQTLRAHLGALLS	RASA4B	411	C9J798
GTHRLTAEERNQAIL	PCBD2	31	Q9H0N5
RLLTNLLSSDHILGI	FMN1	96	Q68DA7
VQIGDHSLRLQTADR	MTCL1	1111	Q9Y4B5
ETILRHTLQLQGLDS	OSBPL9	96	Q96SU4
LEGTLRHLDLSANQL	LRRC3C	126	A6NJW4
IAGTRITQLSLLRHS	LRRC9	836	Q6ZRR7
SHLRLRTGLTNSQGS	LEMD3	896	Q9Y2U8
SLRQLHLNQLIRTSG	MCM2	296	P49736
SGLLQLLFNRSREHG	LTN1	1071	O94822
NSLQLHGLQLRIATR	NSUN2	291	Q08J23
HSSLRLGRNSAARAL	ARHGEF19	206	Q8IW93
GNSLIKAVHQSRLRL	ANKRD34B	11	A5PLL1
ASQLLVLTGQRLAHA	RAB3GAP2	1301	Q9H2M9
LSNQHEFGRLLATSR	PLOD3	506	O60568
AGTLQAAATLHRRLL	ABCC10	991	Q5T3U5
IAHRLNTILNSDRVL	ABCC10	1436	Q5T3U5
RSVLLQVSSRDHGQR	NPHS1	606	O60500
NVGSSHIQLALTLRE	PSTPIP1	86	O43586
TLLHTNLRIKRDSQG	NOTCH2	1571	Q04721
LLRSLDLSGNRLHTL	PODN	431	Q7Z5L7
HQRSNVTLTLRNLKG	IL17RA	261	Q96F46
HSLQLTISRRNGSET	INPP1	231	P49441
RLLRFSSQIHNLGRA	LOXL3	576	P58215
GLRLTQNSQSVLSHL	GPSM2	571	P81274
GLSVRELNRHLRGLS	MAFF	31	Q9ULX9
LERLIIQSSNGHITT	JUN	76	P05412
SHELSNLRLENQLLR	GOLGA5	221	Q8TBA6
ELLQTGLSRRRNSAH	KIF12	206	Q96FN5
LEANSINRSLLALGH	KIF12	281	Q96FN5
LVHLTLSRNTIGQVA	LRFN1	91	Q9P244
RQGLQTTQAHLERLL	GAPVD1	1221	Q14C86
GSHTQNRVLSRITLA	LMLN	391	Q96KR4
QHLERAGENLSLLTS	KCNT1	271	Q5JUK3
LHNATNLRSRSLSGT	KIAA0930	341	Q6ICG6
NSLLLGQSHSLQRDT	CARF	606	Q8N187
RALLQGLSLNSHLSD	CARMIL3	441	Q8ND23
LVLARASGSIDIQHL	DYNC2I1	1021	Q8WVS4
VILAGNLLSHSTQSR	POLD2	241	P49005
LHTVELRGNQLESTL	LRRC23	181	Q53EV4
TSVHELAQRLSGSRL	PCNX2	1971	A6NKB5
LAQRLSGSRLSLHAS	PCNX2	1976	A6NKB5
GTRSQLLANRLFDHS	PCSK5	531	Q92824
LNTTLDLLDRGLQVH	ISOC2	116	Q96AB3
ANLSRTQLLHLGLTQ	KLHDC10	421	Q6PID8
LANRTLLETLLGHSL	PCDH1	816	Q08174
ILRHLLEGQNASVLA	KIF22	111	Q14807
RLSLNNGSITHLVIR	PGAM5	251	Q96HS1
HDAGTRTQILLSLSQ	CUL7	191	Q14999
SLLHLSSRLNGALRQ	CUL7	1006	Q14999
DLLRHTGRLSNLSLE	PRAMEF18	396	Q5VWM3
SHGQRDTAQILLLRG	HACE1	206	Q8IYU2
LQAASGERHSLLLLT	HERC6	26	Q8IVU3
RVNLTRLHTLGDNLL	LAMB2	246	P55268
LALGRARHTQAELQR	LAMB2	1451	P55268
RGLSALQSLRLDANH	LGR4	126	Q9BXB1
TTLENGLIHLRSRDT	POLG2	446	Q9UHN1
LVSQLEQLHRQGLLS	TUBGCP2	306	Q9BSJ2
DTRNVVRASHLLNTL	TUBGCP5	426	Q96RT8
ITTIRNLEGLQNLHS	LRRC46	56	Q96FV0
NRNLRSLNLGGTHLK	NLRP5	836	P59047
QRLSLHNDGARLVAL	LRRC8E	561	Q6NSJ5
LLSSLNELGERQLVH	AR	701	P10275
QTAVLQGRLLRSHSL	HFE	16	Q30201
GLARQVSSLLTNHLA	HECTD4	1351	Q9Y4D8
LLLHLSLSSQAGDRR	HPSE2	31	Q8WWQ2
HVLLQLRQRFSGLAR	PELP1	306	Q8IZL8
LNQILRQSTTHLADG	HUWE1	3966	Q7Z6Z7
HSRETVILRLDQGNL	CRNN	446	Q9UBG3
VILRLDQGNLHTSVS	CRNN	451	Q9UBG3
IQLRRELASVNGHSG	PRPF39	266	Q86UA1
NFLHQSRALLGLTRG	OXER1	361	Q8TDS5
ILLSQSVRQALHSGQ	ALDH18A1	131	P54886
EISHRIRQLGNGSLA	HMCN1	4391	Q96RW7
RLAGSLLTQALESHA	MOGS	351	Q13724
ERQSHSLRNLNIGSS	PTPN21	466	Q16825
LPRLTHLNLSRNSLT	LRRC32	196	Q14392
LRTLAQISALDIGAH	ACP4	231	Q9BZG2
RLSGLRTLNLHNNLI	PODNL1	96	Q6PEZ8
RTLNLHNNLISSEGL	PODNL1	101	Q6PEZ8
GALVLGQSLRRHRLT	GYG2	51	O15488
HGRRLLLSEEASLNI	ARHGAP33	171	O14559
SSQASGAGLQRLHRL	ARHGAP33	641	O14559
LTTHAGIRNSLLTIL	DYNC2H1	1391	Q8NCM8
RSGLRGQLLALTIQH	DYNC2H1	3396	Q8NCM8
QGSSRRLLTEQETHR	EFCAB5	556	A4FU69
NRLSTHLQQEGSELL	FASTKD5	531	Q7L8L6
LREVLHLLRSTGNTQ	TTC26	521	A0AVF1
DLNDLRRVHNLLVSS	HEATR5B	1381	Q9P2D3
AHALSLLRGLSQLRA	KLHL21	16	Q9UJP4
QHSQALLRGLLALRD	KLHL22	31	Q53GT1
GRSINLALSHRGRQA	KMO	51	O15229
VLVTSRRLQNAHTGL	HS1BP3	6	Q53T59
LNSNLHRLVQRTSVL	COG1	861	Q8WTW3
RQLRASHLGNELEGT	C2CD2L	291	O14523
ARLQLQGLDLSSRSL	CENPF	1641	P49454
RSLNSLRSSLLEHQG	CPLANE1	466	Q9H799
SAVRLLRSHQDLNAL	FANCA	46	O15360
LVQALSGLHLSADRL	DUSP16	376	Q9BY84
GQRETQRVALTHLTL	CEP250	1581	Q9BV73
GLHQSVRELQLTLAQ	CEP250	2091	Q9BV73
RKNSLLDHRLGISQS	ID2B	11	Q14602
GQSLTQRLHALKLRS	GNAS	156	O95467
LLHAATRQAAGIRLQ	DDX12P	391	Q92771
DLQTAILLLAHGSRE	AGAP7P	576	Q5VUJ5
NIERGLRGVRHNSSL	ANGPT4	236	Q9Y264
RSLRGSINRIVNESH	CCP110	246	O43303
RILSVNGVNLRNATH	DLG3	431	Q92796
LLSQTHRHLLDGIQR	CSAD	281	Q9Y600
TTQHLRLLIRGQDQD	CEP192	1796	Q8TEP8
GAQAKLERLLLHSNR	GP5	191	P40197
LHSNRLVSLDSGLLN	GP5	201	P40197
QHSLRLLDSVSRLQG	LAMC2	846	Q13753
ASTLVHLDLSGNVLR	CARMIL1	336	Q5VZK9
GALNSSLQLLEDRLH	EMILIN1	791	Q9Y6C2
LTQLLNARGHEVTLV	SDR39U1	16	Q9NRG7
SLQIQLHNTRDALGR	CCDC144A	981	A2RUR9
LHNTRDALGRESLIL	CCDC144A	986	A2RUR9
ARNHLTDRLNLIITS	ENPP7	231	Q6UWV6
LQASGDAQLRRTRLH	DHDDS	286	Q86SQ9
QNIRGSNLEETLLLH	SLC15A5	541	A6NIM6
ESNSSQLLLRRHAGL	SCARA5	191	Q6ZMJ2
LDREIRLQRLSHSGS	SCNN1D	351	P51172
QRIEARTHLQLGSVL	MAU2	61	Q9Y6X3
ANLHITALLNVSRRT	DUSP5	201	Q16690
QLDSIHRRQGSSTSL	DYRK2	126	Q92630
LHGLSFSVLRAQNRD	CFAP74	1141	Q9C0B2
TLRSLDASHNLLRAL	LRRN4	76	Q8WUT4
LLRALSTSELGHLEQ	LRRN4	86	Q8WUT4
NLRSLQSLRLDANHI	LGR5	136	O75473
LRILLLSQDRNHNSS	MAP3K3	116	Q99759
AGSIDHISIRQLQLI	MICAL2	151	O94851
RQAHQLLVALVGDSL	MICAL2	386	O94851
AHTLLGLLRNAQELL	PRSS56	401	P0CW18
KRILGRVNLSLNDSH	PRR14L	1166	Q5THK1
NIARRLFHLNATTGL	PCDH11Y	326	Q9BZA8
LLRSSNRRLEQLHGE	PKN3	56	Q6P5Z2
VNTEVRTRLLGHLAN	HES1	131	Q14469
HARLNLDGLVVRNSS	ICAM4	211	Q14773
SSSLLRAVAHLRSQL	ABCB8	56	Q9NUT2
ITSQTEGLSRLLRQH	FES	76	P07332
HAARIINDLLQSLRS	KHSRP	381	Q92945
LHLLSREQAARALSQ	RTL1	1306	A6NKG5
EARLQSLRNIHTLLD	SYVN1	501	Q86TM6
LGQVRVSRALHASAL	SFI1	231	A8K8P3
LLHRQSTQLLAQRLS	SFI1	806	A8K8P3
EGHLTLLRSSLVNNR	DROSHA	1171	Q9NRR4
TARLTRGQLQHLGTR	UBOX5	446	O94941
SLAQHTSRVLGIELL	TRMT2B	361	Q96GJ1
SHASLSGILRQLRQT	SYNE1	1876	Q8NF91
RNAFRGLRDLTHLSL	LGI2	126	Q8N0V4
SKNALRGLRSLTHLS	LGI4	116	Q8N135
NHGTRESLEALLQRA	PRPF6	586	O94906
RLQHLQASLSQRLGS	RECQL4	171	O94761
NAHINELLSVRRGAS	MTERF4	106	Q7Z6M4
DLLRHTGRLSNLSLE	PRAMEF19	396	Q5SWL8
QRLQGKESHLDTLSR	FASTKD3	476	Q14CZ7
LTTQGSRNLRAAHAL	PTCH2	1041	Q9Y6C5
LKDLLRHTGRLSNLS	PRAMEF22	396	A3QJZ6
RLLGLHTQSRSAIVQ	SMARCD3	271	Q6STE5
TRAELTRLQHQTELG	TAOK2	701	Q9UL54
NALRLTHESLLIQEG	SH3TC1	196	Q8TE82
SSGHLIQELRRGSQA	WDR45B	216	Q5MNZ6
LLRGSSRRLDLLHQQ	PKN1	76	Q16512
RLLEVNQQSLLGLTH	SCRIB	1156	Q14160
HIIRTDQGLLLRSLQ	SEMA3A	626	Q14563
SSLQRSNGRSFLELH	STARD9	3966	Q9P2P6
SHVDRNLLLLLTGQN	FAM83F	266	Q8NEG4
LLQQHREFGRLLSTL	SPTBN5	1246	Q9NRC6
TLSLLQLGLDEHNRV	CEP164	1441	Q9UPV0
LRLRNITIANHEGTL	CCNB1IP1	181	Q9NPC3
RAVHNSRLKSRQGLL	CHST7	281	Q9NS84
VLRGHLDSVNDLRTQ	CLEC4F	256	Q8N1N0
RLAALAGHLSINQDL	CHPF2	191	Q9P2E5
RNTGLLESQLSRHDQ	TRAF3	376	Q13114
LSNGHLDTFRLSLAR	ZBTB7B	486	O15156
HLNRILQEDLGVLTS	TEP1	2361	Q99973
RGTLLKAQIRHQSLD	TIAM2	1646	Q8IVF5
LGKRLSEDSSRHQLL	MIS18A	31	Q9NYP9
ALTLTSQALHIQRLR	SPHK2	66	Q9NRA0
QLHLRGLQNSASDLR	SRCIN1	651	Q9C0H9
SGLTLLRLNLRSNHF	SLITRK5	526	O94991
RDALLAGSLNNTLHL	TMEM94	466	Q12767
SLRLLQSHLRAQVVA	SLC39A1	226	Q9NY26
EQTRSLDGRLQVSHR	SMAD2	106	Q15796
VRVQGNDISHRLRLS	VSTM2B	101	A6NLU5
LTSAQLQRLTNLHGA	WDR97	791	A6NE52
LQRLTNLHGAASLSE	WDR97	796	A6NE52
SHQDLSQRVADRLGL	PRPS2	11	P11908
SRGLGDHQLRVLDTN	PPM1M	336	Q96MI6
ALDTLGQTALHRAAL	TNKS	586	O95271
RHNLGDTRLGQVSAL	SPSB2	236	Q99619
LTSQQHAILIDLGRT	TBC1D1	841	Q86TI0
GSHTSLQEFLRQLLT	NISCH	826	Q9Y2I1
SQLSVDRRHLVLSSG	PXDN	471	Q92626
LTNSGNLIVHLRSLN	ZBTB44	496	Q8NCP5
SLRDQRLQLSHDLLG	NMB	76	P08949
TLHLLLTLARTQQGA	NUP188	1336	Q5SRE5
SLRLLSLHGNDISVV	SLIT2	826	O94813
RLLHGDRLVASTLQG	SIGLEC1	1016	Q9BZZ2
ATTLHLLQLSGQRSL	TP53BP1	336	Q12888
TLALGRASLAIHRLN	TTC23L	216	Q6PF05
SRALNLGAATVLRRH	nan	106	Q6ZWC4
NTDSAAGLLIRSIHL	RALGAPB	751	Q86X10
RTHALLSDVQLLLGT	MYO18B	1806	Q8IUG5
RAINSLGIHVLDSSR	WRNIP1	391	Q96S55
QQLLRGRSHLQGSLA	nan	161	Q6ZR54
NQTLDLIRHLRIHTG	ZNF569	196	Q5MCW4
LHNSEVGRQALRASL	WNT11	191	O96014
LGRLNLSKTHDSSRQ	ZNF26	111	P17031
ESGRSLIINHLDLTR	TTC12	371	Q9H892
SRDSRGNNILHALVT	TRPV3	291	Q8NET8
DVGKQQLLSLHRSSR	PLEKHG1	1201	Q9ULL1
LRSLRLLSLHGNDIS	SLIT1	831	O75093
RDGLRALSSLLVHGN	RIPOR1	1096	Q6ZS17
ESAKRLLQTLHRTQG	ZFYVE26	381	Q68DK2
AVAQLAGQLLIRLSH	TFR2	621	Q9UP52
RARHLQSLGATLREL	XRCC3	231	O43542
ELRSCLLHLTLQGQR	TTC31	411	Q49AM3
LLITGTLHQRSIAEL	ATP6V0D1	111	P61421
SSQLQIAGLEHLREL	GOLGB1	1376	Q14789
LSHLQNLIRELRSSS	GOLGB1	2981	Q14789
LRTNRSIQSLFLHGS	LRRC73	81	Q5JTD7
ESSGSRLIQQRLLHQ	MMUT	21	P22033
RALLAGQRHLLTAQD	NFKB2	471	Q00653