Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsuperoxide-generating NADPH oxidase activator activity

NCF1 NCF1C NCF1B

1.34e-0510983GO:0016176
GeneOntologyMolecularFunctionlarge conductance calcium-activated potassium channel activity

KCNU1 KCNMA1

2.38e-052982GO:0060072
GeneOntologyMolecularFunctionsuperoxide-generating NAD(P)H oxidase activity

NCF1 NCF1C NCF1B

2.44e-0512983GO:0016175
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

NCF1 NCF1C NCF1B

1.23e-0420983GO:0050664
GeneOntologyMolecularFunctionenzyme regulator activity

ST20 SPOCK1 NCF1 CST8 RCBTB2 BCL2A1 AGAP11 PRKAG3 SERPINB9 MGAT5 GUCA1A ANGPTL4 PRKAG1 MAP3K13 NCF1C NCF1B RECK

5.04e-0414189817GO:0030234
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate binding

NCF1 NCF1C NCF1B

6.69e-0435983GO:0043325
GeneOntologyBiologicalProcessneutrophil-mediated killing of gram-positive bacterium

NCF1 NCF1C NCF1B

1.00e-065973GO:0070946
GeneOntologyBiologicalProcessnegative regulation of smooth muscle contraction

NCF1 KCNMA1 NCF1C NCF1B

3.15e-0622974GO:0045986
GeneOntologyBiologicalProcessNADP catabolic process

NCF1 NCF1C NCF1B

3.48e-067973GO:0006742
GeneOntologyBiologicalProcessneutrophil-mediated killing of fungus

NCF1 NCF1C NCF1B

3.48e-067973GO:0070947
GeneOntologyBiologicalProcessregulation of respiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

1.62e-0511973GO:0060264
GeneOntologyBiologicalProcessnegative regulation of muscle contraction

NCF1 KCNMA1 NCF1C NCF1B

2.15e-0535974GO:0045932
GeneOntologyBiologicalProcessrespiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

2.79e-0513973GO:0002536
GeneOntologyBiologicalProcessregulation of smooth muscle contraction

CALD1 NCF1 KCNMA1 NCF1C NCF1B

3.55e-0579975GO:0006940
GeneOntologyBiologicalProcessneutrophil-mediated killing of bacterium

NCF1 NCF1C NCF1B

5.40e-0516973GO:0070944
GeneOntologyBiologicalProcessnucleoside phosphate catabolic process

ENPP3 NCF1 PRKAG3 ENTPD1 PRKAG1 NCF1C NCF1B

7.25e-05216977GO:1901292
GeneOntologyBiologicalProcessresponse to yeast

NCF1 NCF1C NCF1B

7.82e-0518973GO:0001878
GeneOntologyBiologicalProcessnucleotide metabolic process

ENPP3 NCF1 MAGI3 ADCY7 PRKAG3 FCSK LRGUK GUCA1A ENTPD1 PRKAG1 NCF1C NCF1B

8.71e-056849712GO:0009117
GeneOntologyBiologicalProcessneutrophil-mediated killing of symbiont cell

NCF1 NCF1C NCF1B

9.25e-0519973GO:0070943
GeneOntologyBiologicalProcessnucleoside phosphate metabolic process

ENPP3 NCF1 MAGI3 ADCY7 PRKAG3 FCSK LRGUK GUCA1A ENTPD1 PRKAG1 NCF1C NCF1B

9.59e-056919712GO:0006753
GeneOntologyBiologicalProcessrespiratory burst involved in defense response

NCF1 NCF1C NCF1B

1.08e-0420973GO:0002679
GeneOntologyBiologicalProcesspositive regulation of protein modification process

HGF DCUN1D5 ARRDC4 NCF1 REG3G MAGI3 PTK2B FANCI TLR1 PRKAG1 MAP3K13 CAMTA1 RAP2C BANK1

1.21e-049379714GO:0031401
GeneOntologyBiologicalProcessneutrophil mediated cytotoxicity

NCF1 NCF1C NCF1B

1.26e-0421973GO:0070942
GeneOntologyBiologicalProcesshydrogen peroxide biosynthetic process

NCF1 NCF1C NCF1B

1.46e-0422973GO:0050665
GeneOntologyBiologicalProcesspurine nucleotide metabolic process

ENPP3 NCF1 MAGI3 ADCY7 PRKAG3 LRGUK GUCA1A ENTPD1 PRKAG1 NCF1C NCF1B

1.56e-046199711GO:0006163
GeneOntologyBiologicalProcessregulation of respiratory burst

NCF1 NCF1C NCF1B

1.67e-0423973GO:0060263
GeneOntologyBiologicalProcesscellular defense response

NCF1 PTK2B NCF1C NCF1B

1.83e-0460974GO:0006968
GeneOntologyBiologicalProcesspurine nucleotide catabolic process

NCF1 PRKAG3 ENTPD1 PRKAG1 NCF1C NCF1B

2.21e-04182976GO:0006195
GeneOntologyBiologicalProcesspositive regulation of phosphate metabolic process

HGF DSCAM NCF1 REG3G MAGI3 PTK2B GUCA1A TLR1 PRKAG1 MAP3K13 CAMTA1 RAP2C BANK1

2.38e-048799713GO:0045937
GeneOntologyBiologicalProcesspositive regulation of phosphorus metabolic process

HGF DSCAM NCF1 REG3G MAGI3 PTK2B GUCA1A TLR1 PRKAG1 MAP3K13 CAMTA1 RAP2C BANK1

2.38e-048799713GO:0010562
GeneOntologyBiologicalProcesspurine-containing compound metabolic process

ENPP3 NCF1 MAGI3 ADCY7 PRKAG3 LRGUK GUCA1A ENTPD1 PRKAG1 NCF1C NCF1B

2.45e-046529711GO:0072521
GeneOntologyBiologicalProcesspyridine nucleotide catabolic process

NCF1 PRKAG3 PRKAG1 NCF1C NCF1B

2.48e-04119975GO:0019364
GeneOntologyBiologicalProcessnucleobase-containing small molecule metabolic process

ENPP3 NCF1 MAGI3 ADCY7 PRKAG3 FCSK LRGUK GUCA1A ENTPD1 PRKAG1 NCF1C NCF1B

2.52e-047679712GO:0055086
GeneOntologyBiologicalProcesspurine-containing compound catabolic process

NCF1 PRKAG3 ENTPD1 PRKAG1 NCF1C NCF1B

2.63e-04188976GO:0072523
GeneOntologyBiologicalProcesspyridine-containing compound catabolic process

NCF1 PRKAG3 PRKAG1 NCF1C NCF1B

2.89e-04123975GO:0072526
GeneOntologyBiologicalProcessregulation of phosphate metabolic process

HGF DSCAM NCF1 REG3G MAGI3 PRKAG3 PTK2B MGAT5 GUCA1A TLR1 ENTPD1 PRKAG1 PRKDC MAP3K13 CAMTA1 RAP2C BANK1

3.14e-0414219717GO:0019220
GeneOntologyBiologicalProcessregulation of phosphorus metabolic process

HGF DSCAM NCF1 REG3G MAGI3 PRKAG3 PTK2B MGAT5 GUCA1A TLR1 ENTPD1 PRKAG1 PRKDC MAP3K13 CAMTA1 RAP2C BANK1

3.19e-0414239717GO:0051174
GeneOntologyBiologicalProcessorganophosphate catabolic process

ENPP3 NCF1 PRKAG3 ENTPD1 PRKAG1 NCF1C NCF1B

3.65e-04281977GO:0046434
GeneOntologyBiologicalProcesspurine nucleoside diphosphate metabolic process

MAGI3 PRKAG3 LRGUK ENTPD1 PRKAG1

4.00e-04132975GO:0009135
GeneOntologyBiologicalProcesspurine ribonucleoside diphosphate metabolic process

MAGI3 PRKAG3 LRGUK ENTPD1 PRKAG1

4.00e-04132975GO:0009179
GeneOntologyBiologicalProcesssmooth muscle contraction

CALD1 NCF1 KCNMA1 NCF1C NCF1B

4.14e-04133975GO:0006939
GeneOntologyBiologicalProcesspositive regulation of protein metabolic process

HGF ST20 DCUN1D5 ARRDC4 NCF1 REG3G MAGI3 BCL2A1 PTK2B FANCI TLR1 PRKAG1 PRKDC MAP3K13 CAMTA1 RAP2C BANK1

4.23e-0414589717GO:0051247
GeneOntologyBiologicalProcessnucleotide catabolic process

NCF1 PRKAG3 ENTPD1 PRKAG1 NCF1C NCF1B

4.51e-04208976GO:0009166
GeneOntologyBiologicalProcessnegative regulation of dopamine secretion

ENTPD1 GABBR1

4.53e-047972GO:0033602
GeneOntologyBiologicalProcessnegative regulation of hydrolase activity

SPOCK1 CST8 BCL2A1 SERPINB9 MGAT5 ANGPTL4 RECK

5.19e-04298977GO:0051346
GeneOntologyBiologicalProcessregulation of protein modification process

HGF DCUN1D5 SPOPL ARRDC4 NCF1 REG3G MAGI3 PTK2B MGAT5 FANCI TLR1 PRKAG1 PRKDC MAP3K13 CAMTA1 RAP2C BANK1

5.34e-0414889717GO:0031399
GeneOntologyBiologicalProcessregulation of dopamine secretion

SYT7 ENTPD1 GABBR1

5.43e-0434973GO:0014059
GeneOntologyBiologicalProcessribonucleoside diphosphate metabolic process

MAGI3 PRKAG3 LRGUK ENTPD1 PRKAG1

5.77e-04143975GO:0009185
GeneOntologyBiologicalProcessnucleoside diphosphate metabolic process

MAGI3 PRKAG3 LRGUK ENTPD1 PRKAG1

6.95e-04149975GO:0009132
GeneOntologyBiologicalProcesskilling by host of symbiont cells

NCF1 NCF1C NCF1B

7.55e-0438973GO:0051873
GeneOntologyBiologicalProcesstooth mineralization

CFTR WLS SLC24A4

7.55e-0438973GO:0034505
GeneOntologyBiologicalProcessleukotriene metabolic process

NCF1 NCF1C NCF1B

9.44e-0441973GO:0006691
GeneOntologyBiologicalProcessdopamine secretion

SYT7 ENTPD1 GABBR1

9.44e-0441973GO:0014046
GeneOntologyCellularComponentNADPH oxidase complex

NCF1 NCF1C NCF1B

7.51e-0518973GO:0043020
GeneOntologyCellularComponentdendrite

TANC2 CALD1 DSCAM CFTR NCF1 CKAP5 WLS SYT7 PTK2B KCNMA1 NCF1C NCF1B GABBR1

1.65e-048589713GO:0030425
GeneOntologyCellularComponentdendritic tree

TANC2 CALD1 DSCAM CFTR NCF1 CKAP5 WLS SYT7 PTK2B KCNMA1 NCF1C NCF1B GABBR1

1.69e-048609713GO:0097447
GeneOntologyCellularComponentcell body

CALD1 DSCAM CFTR NCF1 CKAP5 SYT7 PTK2B ENTPD1 KCNMA1 STK39 NCF1C NCF1B GABBR1

3.56e-049299713GO:0044297
GeneOntologyCellularComponentneuronal cell body

CALD1 DSCAM CFTR NCF1 CKAP5 SYT7 PTK2B ENTPD1 KCNMA1 NCF1C NCF1B GABBR1

4.81e-048359712GO:0043025
MousePhenoimpaired granulocyte bactericidal activity

NCF1 PLAU NCF1C NCF1B

2.14e-0710814MP:0005074
MousePhenoimpaired smooth muscle contractility

NCF1 ENTPD1 STK39 NCF1C NCF1B

1.63e-0635815MP:0000740
MousePhenodecreased susceptibility to Orthomyxoviridae infection

OLAH NCF1 NCF1C NCF1B

3.01e-0618814MP:0020947
MousePhenoabnormal angiotensin I-converting enzyme activity

NCF1 NCF1C NCF1B

3.70e-066813MP:0013254
MousePhenoincreased angiotensin I-converting enzyme activity

NCF1 NCF1C NCF1B

3.70e-066813MP:0003184
MousePhenoliver abscess

NCF1 NCF1C NCF1B

6.45e-067813MP:0003332
MousePhenodecreased vasoconstriction

NCF1 STK39 NCF1C NCF1B

7.07e-0622814MP:0003026
MousePhenoabnormal susceptibility to Orthomyxoviridae infection

OLAH NCF1 REG3G NCF1C NCF1B

1.46e-0554815MP:0020945
MousePhenotestis degeneration

NSUN2 DHCR24 SPOCD1

1.20e-0417813MP:0013600
MousePhenoabnormal vascular endothelial cell physiology

NCF1 ENTPD1 NCF1C NCF1B

1.54e-0447814MP:0004003
MousePhenoimpaired sperm capacitation

CFTR CST8 KCNU1

1.70e-0419813MP:0003666
MousePhenoabnormal vasoconstriction

NCF1 STK39 NCF1C NCF1B

1.97e-0450814MP:0000250
MousePhenospiral ligament degeneration

HGF THRB

1.97e-044812MP:0004864
MousePhenoabnormal spiral ligament morphology

HGF GRID1 THRB

2.31e-0421813MP:0004288
MousePhenoabnormal enzyme/coenzyme activity

NCF1 SLC6A8 SERPINB9 XIRP2 ANGPTL4 PTRH2 NCF1C NCF1B

2.52e-04287818MP:0005584
MousePhenoabnormal sperm capacitation

CFTR CST8 KCNU1

2.67e-0422813MP:0013286
MousePhenoincreased circulating renin level

NCF1 NCF1C NCF1B

3.05e-0423813MP:0003352
MousePhenoabnormal muscle physiology

DSCAM NCF1 NEB SYT7 SLC6A8 PTK2B THRB XIRP2 ENTPD1 KCNMA1 PTRH2 PLAU STK39 NCF1C NCF1B

3.36e-049548115MP:0002106
MousePhenoabnormal intestinal mucosa morphology

CFTR NCF1 ANGPTL4 PRKDC NCF1C NCF1B

3.50e-04162816MP:0000511
MousePhenoabnormal neutrophil physiology

NCF1 BCL2A1 ENTPD1 PLAU NCF1C NCF1B

3.86e-04165816MP:0002463
MousePhenoabnormal blood vessel physiology

NCF1 PTK2B MYOF ANGPTL4 ENTPD1 PLAU STK39 NCF1C NCF1B

4.45e-04394819MP:0000249
DomainSPOC

SPOCD1 SPEN

1.53e-044952PS50917
DomainK_chnl_Ca-activ_BK_asu

KCNU1 KCNMA1

1.53e-044952IPR003929
DomainBK_channel_a

KCNU1 KCNMA1

1.53e-044952PF03493
DomainSPOC_C

SPOCD1 SPEN

3.79e-046952IPR012921
DomainSPOC

SPOCD1 SPEN

3.79e-046952PF07744
DomainBlc2_fam

ST20 BCL2A1

1.37e-0311952IPR026298
DomainDynein_HC_stalk

DNHD1 DNAH5

2.24e-0314952IPR024743
DomainDynein_heavy_dom-2

DNHD1 DNAH5

2.24e-0314952IPR013602
DomainDHC_N2

DNHD1 DNAH5

2.24e-0314952PF08393
DomainMT

DNHD1 DNAH5

2.24e-0314952PF12777
DomainDHC_fam

DNHD1 DNAH5

2.57e-0315952IPR026983
DomainDynein_heavy_dom

DNHD1 DNAH5

2.57e-0315952IPR004273
DomainDynein_heavy

DNHD1 DNAH5

2.57e-0315952PF03028
DomainCBS

PRKAG3 PRKAG1

2.93e-0316952SM00116
DomainKringle

HGF PLAU

3.31e-0317952IPR000001
DomainKringle_CS

HGF PLAU

3.31e-0317952IPR018056
DomainKRINGLE_2

HGF PLAU

3.31e-0317952PS50070
DomainKringle

HGF PLAU

3.31e-0317952PF00051
DomainKRINGLE_1

HGF PLAU

3.31e-0317952PS00021
DomainKR

HGF PLAU

3.31e-0317952SM00130
DomainCBS_dom

PRKAG3 PRKAG1

4.58e-0320952IPR000644
DomainCBS

PRKAG3 PRKAG1

4.58e-0320952PF00571
DomainCBS

PRKAG3 PRKAG1

4.58e-0320952PS51371
DomainGUANYLATE_KINASE_2

MAGI3 LRGUK

6.04e-0323952PS50052
DomainGUANYLATE_KINASE_1

MAGI3 LRGUK

6.04e-0323952PS00856
PathwayREACTOME_CROSS_PRESENTATION_OF_PARTICULATE_EXOGENOUS_ANTIGENS_PHAGOSOMES

NCF1 NCF1C NCF1B

9.64e-069703MM14524
Pubmed

Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity.

CFTR NCF1 NCF1C NCF1B

6.43e-114100434207085
Pubmed

Dysregulated Calcium Homeostasis in Cystic Fibrosis Neutrophils Leads to Deficient Antimicrobial Responses.

CFTR NCF1 NCF1C NCF1B

6.43e-114100430120123
Pubmed

Urokinase plasminogen activator upregulates paraoxonase 2 expression in macrophages via an NADPH oxidase-dependent mechanism.

NCF1 PLAU NCF1C NCF1B

3.21e-105100418436804
Pubmed

Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes.

NCF1 PRKDC NCF1C NCF1B

3.21e-105100421715554
Pubmed

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.

NCF1 NCF1C NCF1B

2.31e-083100327044504
Pubmed

NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.

NCF1 NCF1C NCF1B

2.31e-083100318787174
Pubmed

Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.

NCF1 NCF1C NCF1B

2.31e-083100324873968
Pubmed

p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.

NCF1 NCF1C NCF1B

2.31e-083100322184329
Pubmed

Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.

NCF1 NCF1C NCF1B

2.31e-083100333545139
Pubmed

Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.

NCF1 NCF1C NCF1B

2.31e-083100320142487
Pubmed

p47(phox) contributes to albuminuria and kidney fibrosis in mice.

NCF1 NCF1C NCF1B

2.31e-083100325565313
Pubmed

Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.

NCF1 NCF1C NCF1B

2.31e-083100339357591
Pubmed

Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.

NCF1 NCF1C NCF1B

2.31e-083100311435342
Pubmed

Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8+ T Cell Activation via Cross-Presentation in Type 1 Diabetes.

NCF1 NCF1C NCF1B

2.31e-083100331118934
Pubmed

Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.

NCF1 NCF1C NCF1B

2.31e-083100316041040
Pubmed

Intermittent hypoxia has organ-specific effects on oxidative stress.

NCF1 NCF1C NCF1B

2.31e-083100318703411
Pubmed

Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion.

NCF1 NCF1C NCF1B

2.31e-083100317307863
Pubmed

Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.

NCF1 NCF1C NCF1B

2.31e-083100327829407
Pubmed

The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.

NCF1 NCF1C NCF1B

2.31e-083100322376231
Pubmed

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.

NCF1 NCF1C NCF1B

2.31e-083100323918780
Pubmed

NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells.

NCF1 NCF1C NCF1B

2.31e-083100328274989
Pubmed

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

NCF1 NCF1C NCF1B

2.31e-083100312364355
Pubmed

NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities.

NCF1 NCF1C NCF1B

2.31e-083100334557202
Pubmed

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.

NCF1 NCF1C NCF1B

2.31e-083100328467721
Pubmed

P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.

NCF1 NCF1C NCF1B

2.31e-083100310670582
Pubmed

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

NCF1 NCF1C NCF1B

2.31e-083100326528554
Pubmed

The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis.

NCF1 NCF1C NCF1B

2.31e-083100319052348
Pubmed

Effect of early particulate air pollution exposure on obesity in mice: role of p47phox.

NCF1 NCF1C NCF1B

2.31e-083100320864666
Pubmed

Reactive oxygen species delay control of lymphocytic choriomeningitis virus.

NCF1 NCF1C NCF1B

2.31e-083100323328631
Pubmed

p47phox-Dependent Oxidant Signalling through ASK1, MKK3/6 and MAPKs in Angiotensin II-Induced Cardiac Hypertrophy and Apoptosis.

NCF1 NCF1C NCF1B

2.31e-083100334572995
Pubmed

Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.

NCF1 NCF1C NCF1B

2.31e-083100317114280
Pubmed

B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.

NCF1 NCF1C NCF1B

2.31e-083100325989352
Pubmed

Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase.

NCF1 NCF1C NCF1B

2.31e-083100317404617
Pubmed

Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction.

NCF1 NCF1C NCF1B

2.31e-083100317332431
Pubmed

Lpp of Escherichia coli K1 inhibits host ROS production to counteract neutrophil-mediated elimination.

NCF1 NCF1C NCF1B

2.31e-083100336592568
Pubmed

Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression.

NCF1 NCF1C NCF1B

2.31e-083100330504842
Pubmed

Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism.

NCF1 NCF1C NCF1B

2.31e-083100333705493
Pubmed

Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis.

NCF1 NCF1C NCF1B

2.31e-083100323965970
Pubmed

Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice.

NCF1 NCF1C NCF1B

2.31e-083100315513930
Pubmed

Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKCdelta but not Akt.

NCF1 NCF1C NCF1B

2.31e-083100315033459
Pubmed

Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles.

NCF1 NCF1C NCF1B

2.31e-083100320828610
Pubmed

p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation.

NCF1 NCF1C NCF1B

2.31e-083100320817944
Pubmed

NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions.

NCF1 NCF1C NCF1B

2.31e-083100336853827
Pubmed

Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.

NCF1 NCF1C NCF1B

2.31e-083100323024271
Pubmed

Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells.

NCF1 NCF1C NCF1B

2.31e-083100321253614
Pubmed

Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene.

NCF1 NCF1C NCF1B

2.31e-083100315310853
Pubmed

Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21.

NCF1 NCF1C NCF1B

2.31e-083100331393787
Pubmed

Vascular effects following homozygous disruption of p47(phox) : An essential component of NADPH oxidase.

NCF1 NCF1C NCF1B

2.31e-083100310725280
Pubmed

Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice.

NCF1 NCF1C NCF1B

2.31e-083100334970267
Pubmed

Germ-free mice deficient of reactive oxygen species have increased arthritis susceptibility.

NCF1 NCF1C NCF1B

2.31e-083100325689796
Pubmed

Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation.

NCF1 NCF1C NCF1B

2.31e-083100314993144
Pubmed

Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation.

NCF1 NCF1C NCF1B

2.31e-083100322050439
Pubmed

The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.

NCF1 NCF1C NCF1B

2.31e-083100312031896
Pubmed

NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion.

NCF1 NCF1C NCF1B

2.31e-083100311249873
Pubmed

Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice.

NCF1 NCF1C NCF1B

2.31e-083100315936744
Pubmed

NADPH oxidase p47phox siRNA attenuates adventitial fibroblasts proliferation and migration in apoE(-/-) mouse.

NCF1 NCF1C NCF1B

2.31e-083100325628043
Pubmed

Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p47phox subunit.

NCF1 NCF1C NCF1B

2.31e-083100312560337
Pubmed

Inhibition of endothelial Nox2 activation by LMH001 protects mice from angiotensin II-induced vascular oxidative stress, hypertension and aortic aneurysm.

NCF1 NCF1C NCF1B

2.31e-083100335276443
Pubmed

Reactive oxygen species modulate growth of cerebral aneurysms: a study using the free radical scavenger edaravone and p47phox(-/-) mice.

NCF1 NCF1C NCF1B

2.31e-083100319381132
Pubmed

Identification of a novel NCF-1 (p47-phox) pseudogene not containing the signature GT deletion: significance for A47 degrees chronic granulomatous disease carrier detection.

NCF1 NCF1C NCF1B

2.31e-083100312176908
Pubmed

A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease.

NCF1 NCF1C NCF1B

2.31e-08310039329953
Pubmed

Superoxide prevents nitric oxide-mediated suppression of helper T lymphocytes: decreased autoimmune encephalomyelitis in nicotinamide adenine dinucleotide phosphate oxidase knockout mice.

NCF1 NCF1C NCF1B

2.31e-083100310799876
Pubmed

Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha.

NCF1 NCF1C NCF1B

2.31e-083100311834706
Pubmed

A model of chronic enthesitis and new bone formation characterized by multimodal imaging.

NCF1 NCF1C NCF1B

2.31e-083100330045841
Pubmed

Virulence and cellular interactions of Burkholderia multivorans in chronic granulomatous disease.

NCF1 NCF1C NCF1B

2.31e-083100319635825
Pubmed

The NCF1 variant p.R90H aggravates autoimmunity by facilitating the activation of plasmacytoid dendritic cells.

NCF1 NCF1C NCF1B

2.31e-083100335788118
Pubmed

Hydrophobic bile salts induce hepatocyte shrinkage via NADPH oxidase activation.

NCF1 NCF1C NCF1B

2.31e-083100317310103
Pubmed

Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia.

NCF1 NCF1C NCF1B

2.31e-083100318036262
Pubmed

Transient loss of resistance to pulmonary tuberculosis in p47(phox-/-) mice.

NCF1 NCF1C NCF1B

2.31e-083100310678931
Pubmed

Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.

NCF1 NCF1C NCF1B

2.31e-083100317167081
Pubmed

Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.

NCF1 NCF1C NCF1B

2.31e-083100324358335
Pubmed

Molecular characterization of the mouse p47-phox (Ncf1) gene and comparative analysis of the mouse p47-phox (Ncf1) gene to the human NCF1 gene.

NCF1 NCF1C NCF1B

2.31e-083100310891396
Pubmed

P47phox-/- mice are compromised in expansion and activation of CD8+ T cells and susceptible to Trypanosoma cruzi infection.

NCF1 NCF1C NCF1B

2.31e-083100325474113
Pubmed

NAD(P)H oxidase subunit p47phox is elevated, and p47phox knockout prevents diaphragm contractile dysfunction in heart failure.

NCF1 NCF1C NCF1B

2.31e-083100326209274
Pubmed

NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.

NCF1 NCF1C NCF1B

2.31e-083100311018074
Pubmed

Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

2.31e-08310039116268
Pubmed

Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.

NCF1 NCF1C NCF1B

2.31e-083100320686129
Pubmed

Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.

NCF1 NCF1C NCF1B

2.31e-083100321570954
Pubmed

Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion.

NCF1 NCF1C NCF1B

2.31e-083100312958309
Pubmed

Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.

NCF1 NCF1C NCF1B

2.31e-083100323482812
Pubmed

The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs.

NCF1 NCF1C NCF1B

2.31e-083100310085000
Pubmed

Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.

NCF1 NCF1C NCF1B

2.31e-083100310987289
Pubmed

Methamphetamine alters occludin expression via NADPH oxidase-induced oxidative insult and intact caveolae.

NCF1 NCF1C NCF1B

2.31e-083100321435178
Pubmed

Mycobacterial infection induces higher interleukin-1β and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.

NCF1 NCF1C NCF1B

2.31e-083100329228045
Pubmed

Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate.

NCF1 NCF1C NCF1B

2.31e-083100322155727
Pubmed

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction.

NCF1 NCF1C NCF1B

2.31e-083100324576409
Pubmed

The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues.

NCF1 NCF1C NCF1B

2.31e-083100326645958
Pubmed

NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.

NCF1 NCF1C NCF1B

2.31e-083100324549323
Pubmed

NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity.

NCF1 NCF1C NCF1B

2.31e-083100320881184
Pubmed

Participation of mitochondrial respiratory complex III in neutrophil activation and lung injury.

NCF1 NCF1C NCF1B

2.31e-083100319168575
Pubmed

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation.

NCF1 NCF1C NCF1B

2.31e-083100319503084
Pubmed

Genetic requirement of p47phox for superoxide production by murine microglia.

NCF1 NCF1C NCF1B

2.31e-083100311156938
Pubmed

Genomic structure of the human p47-phox (NCF1) gene.

NCF1 NCF1C NCF1B

2.31e-083100310772875
Pubmed

A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2+ Release During Axonal Specification.

NCF1 NCF1C NCF1B

2.31e-083100327798190
Pubmed

Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species.

NCF1 NCF1C NCF1B

2.31e-083100320702812
Pubmed

Macrophage-derived reactive oxygen species protects against autoimmune priming with a defined polymeric adjuvant.

NCF1 NCF1C NCF1B

2.31e-083100326455429
Pubmed

Conditional haploinsufficiency of NCF1 (encoding p47(phox)), a signaling gene with a heterozygous phenotype potentially subject to natural selection.

NCF1 NCF1C NCF1B

2.31e-083100315626477
Pubmed

NCF1 gene and pseudogene pattern: association with parasitic infection and autoimmunity.

NCF1 NCF1C NCF1B

2.31e-083100319077231
Pubmed

Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.

NCF1 NCF1C NCF1B

2.31e-083100322319452
Pubmed

Early determinants of H2O2-induced endothelial dysfunction.

NCF1 NCF1C NCF1B

2.31e-083100316895801
GeneFamilyPotassium calcium-activated channels

KCNU1 KCNMA1

1.67e-046612255
CoexpressionGAVIN_PDE3B_TARGETS

NCF1 ENTPD1 NCF1C NCF1B

2.37e-06251004MM726
CoexpressionKRIEG_HYPOXIA_NOT_VIA_KDM3A

TANC2 KNTC1 SLC6A8 MYOF UBE2O MGAT5 FANCI ANGPTL4 MKLN1 KCNMA1 STK39 MAP3K21

2.75e-0574610012M2469
CoexpressionWINTER_HYPOXIA_UP

TANC2 SLC6A8 XPO5 ANGPTL4 PLAU

3.23e-05951005M5466
CoexpressionGSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN

TANC2 NCF1 WLS SLC17A9 STK39 CAMTA1

3.38e-051591006M8125
CoexpressionGSE37534_GW1929_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN

XK BBS9 KAT7 MAMDC2 PRKDC SPEN

4.02e-051641006M8989
CoexpressionLAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB

TANC2 VPS13C MAGI3 THRB MKLN1 DNAH5

4.75e-051691006M39230
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

VPS13C NCF1 PTK2B SERPINB9 MGAT5 ENTPD1 NCF1C NCF1B BANK1

5.80e-101941009ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SPOPL ARRDC4 CFTR MAGI3 WLS THRB VWA5B1

2.13e-071861007a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI3 KMT2C MGAT5 THRB MKLN1 KCNMA1 STK39

3.37e-07199100794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellIonocyte-iono-3|World / Class top

DNHD1 KNTC1 CFTR ADCY7 ENTPD1 KCNMA1

2.06e-0616610069c4a780f8af46d7552077c7a0ae0ab1b2413e5d4
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|Myeloid_cells / Location, Cell class and cell subclass

DNHD1 KNTC1 NEB KAT7 FCSK ROM1

2.29e-061691006dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HGF CALD1 KAT7 SERPINB9 TLR1 RECK

3.40e-0618110062b9b460239d67fd480cee60820cdb306109d3567
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HGF CALD1 KAT7 SERPINB9 TLR1 RECK

3.40e-0618110062a1aa4a0ec7bc367857beaff543135e4345c835b
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFTR WLS MGAT5 GUCA1A KCNMA1 IGSF1

3.51e-0618210066e7dac78dc030f74e546b9f6db07556e9bb13ac2
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFTR WLS MGAT5 GUCA1A KCNMA1 IGSF1

3.51e-061821006cd972d30519db706477c6b0c901165b81b74abed
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 MYOF KCNMA1 PLAU STK39 DNAH5

4.10e-06187100687b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 MYOF KCNMA1 PLAU STK39 DNAH5

4.10e-06187100642a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 MYOF KCNMA1 PLAU STK39 DNAH5

4.10e-06187100664afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

TANC2 CFTR THRB DHCR24 MAP3K13 DNAH5

4.23e-061881006ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

WLS MGAT5 MAMDC2 TLR1 ENTPD1 KCNMA1

4.49e-061901006f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCF1 BCL2A1 SLC17A9 ANGPTL4 NCF1C NCF1B

4.63e-061911006a143af67fc3270439f390edec599d2e3d29a107f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCF1 ADCY7 MGAT5 MAMDC2 TLR1 KCNMA1

5.06e-061941006c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 VPS13C NEB KCNMA1 PLAU C7

5.22e-0619510065c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell(01)_IL1RL1+-(1)_GFP|(01)_IL1RL1+ / shred by cell type by condition

ARRDC4 SLC6A8 PTK2B DHCR24 ANGPTL4 HAS3

5.37e-061961006b598b1112242534e139318012b257ed3cb09da83
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HGF CALD1 MAMDC2 ANGPTL4 C7 ADAMTSL2

5.37e-0619610069737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HGF CALD1 MAMDC2 ANGPTL4 C7 ADAMTSL2

5.37e-061961006cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

NCF1 BCL2A1 ADCY7 PTK2B TLR1 KCNMA1

5.53e-061971006e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NCF1 PTK2B ENTPD1 NCF1C NCF1B BANK1

5.53e-061971006fa3cc33c975648172feabb485c3bdd087f1f8ea7
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|lung / Disease (COVID-19 only), tissue and cell type

NCF1 ADCY7 PTK2B SLC24A4 TLR1 KCNMA1

5.53e-0619710063896729740d151f0eb845f1961c7b969bfbdd28d
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

TANC2 DNHD1 NEB SEPSECS KCNMA1 TLCD5

5.53e-06197100615b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

TANC2 DNHD1 NEB SEPSECS KCNMA1 TLCD5

5.53e-061971006a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NEB WLS SLC6A8 MGAT5 PLAU RAP2C

5.69e-0619810064448d13511485a44fe7b549e4b8b6ad7637db624
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HGF CALD1 GRID1 MAMDC2 ENTPD1 ADAMTSL2

6.03e-06200100658b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BCL2A1 KCNU1 XIRP2 ENTPD1 ADAMTSL2

1.79e-0514310054a0f26eef935fe68a1da5d319503059a8a8682dd
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BCL2A1 KCNU1 XIRP2 ENTPD1 ADAMTSL2

1.79e-05143100565328a0a2f3972fac596e07933e74b2ef7cceb84
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DSCAM CFTR MAGI3 STK39 VWA5B1

2.80e-051571005c17c5c01fcb65c453690c265ec4f300ecdfefd34
ToppCellP15-Epithelial-epithelial_progenitor_cell-epi_progenitor|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TANC2 CFTR PRKAG3 MYOF MAP3K21

2.97e-051591005a4bfd59c53237964fc24a24de5c1925fdd01db99
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 KNTC1 ADCY7 BANK1 GABBR1

3.35e-0516310058dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 KNTC1 ADCY7 BANK1 GABBR1

3.35e-051631005fd243ca223079033be480a24817a399f281fa4d4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINB9 SLC24A4 SLC17A9 TLR1 ENTPD1

3.65e-05166100563dc58864268b4e7779e4c45155022556fc634f9
ToppCellSigmoid-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

NCF1 SERPINB9 ENTPD1 KCNMA1 PLAU

3.87e-051681005bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

DNHD1 KNTC1 NEB TLR1 ROM1

4.32e-051721005f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP47 SAXO2 LRGUK SLC24A4 DNAH5

4.57e-051741005f1510b0f7771936adf29ae3572feab55db31832b
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP47 SAXO2 LRGUK SLC24A4 DNAH5

4.57e-0517410055d5d2fc60afff47f997751e8e9ca1367a22d19ec
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ENPP3 GRID1 MYOF THRB KCNU1

4.57e-0517410051d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCellNS-moderate-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HGF SPOCK1 CFTR KCNMA1 MAP3K21

4.70e-051751005a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCelldroplet-Lung-LUNG-30m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP3 CFTR REG3G IGSF1 DNAH5

4.96e-0517710057ac99ff16df94b4e08d361e3d98a7b3af8d6ee3b
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP3 CFTR REG3G IGSF1 DNAH5

4.96e-051771005092a345cb802f183322aa5542341ba2d96d4f06a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NCF1 ADCY7 TLR1 ENTPD1 KCNMA1

5.80e-051831005a97f052950429245c3231464271e1ba539863bba
ToppCellCOVID-19-APC-like-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

ADCY7 SERPINB9 SLC24A4 TLR1 ENTPD1

5.80e-051831005703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 LRGUK SLC24A4 DNAH5 VWA5B1

5.80e-0518310056ca7c2d7c56e0f1b9038ba677b4c1c3dfd63bfce
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 LRGUK SLC24A4 DNAH5 VWA5B1

5.80e-05183100518040d0653286071df959513c63d94b555a5d00a
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFTR GRID1 NEB XIRP2 DNAH5

5.96e-0518410052cbed6462fea2622871bb7e49b0df3d984239281
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFTR WLS MGAT5 GUCA1A KCNMA1

5.96e-051841005a60802e11dcc5f932811260b08a95a32f60f6b19
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFTR WLS MGAT5 GUCA1A KCNMA1

5.96e-05184100539c230d32e4259bc784e0edfd9e2884c96898564
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFTR WLS MGAT5 GUCA1A KCNMA1

5.96e-0518410052a2fb691cc9414ef5b06c26239d2da03d6d7e5c2
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

CALD1 SPOCK1 MAMDC2 C7 ADAMTSL2

5.96e-0518410052b7e6f91e11c228f0521e099886867d9e998e78d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFTR GRID1 NEB XIRP2 DNAH5

5.96e-051841005ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BCL2A1 ADCY7 SERPINB9 SLC24A4 ENTPD1

5.96e-0518410054f4aeef3b821a003e857fe4a195124d44b2d7479
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFTR GRID1 NEB XIRP2 DNAH5

5.96e-0518410052b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

CFTR MAGI3 DHCR24 MAP3K13 DNAH5

6.11e-051851005cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

HGF WLS MGAT5 MAMDC2 TLR1

6.11e-0518510058207f9eff113eed429e961748c6b17d672a13b33
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 CFTR MAGI3 MAP3K21 VWA5B1

6.11e-0518510053d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFTR MAGI3 DHCR24 STK39 DNAH5

6.27e-0518610052ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellIPF-Myeloid-cDC1|World / Disease state, Lineage and Cell class

SERPINB9 THRB SLC24A4 ENTPD1 MAP3K13

6.27e-051861005962c2dada19185628ead77c32fcb07fa95114247
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HGF CALD1 MAMDC2 ANGPTL4 C7

6.27e-0518610055473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 MYOF KCNMA1 PLAU STK39

6.43e-05187100577886f99c229610abd28c4c370d2c7d1536c9782
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-B|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCF1 BCL2A1 ANGPTL4 NCF1C NCF1B

6.59e-051881005977ebc0f88cb3ea3c422c85d84b3546229af5d3f
ToppCell-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

CALD1 SPOCK1 MAMDC2 C7 ADAMTSL2

6.59e-051881005038f48e8daaeb72716e975d22a6b004a90654960
ToppCell343B-Lymphocytic-ILC-ILC-1|343B / Donor, Lineage, Cell class and subclass (all cells)

RCBTB2 NSUN2 SP140L ZBTB21 STK39

6.59e-0518810058f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NCF1 BCL2A1 LY6G6C ADCY7 SLC24A4

6.59e-0518810054e27ada1bda88811b73376c8a6136cbfc83bfdb9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CFTR MAGI3 WLS THRB VWA5B1

6.59e-051881005e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HGF CALD1 GRID1 PLAU DNAH5

6.59e-051881005997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SAXO2 THRB SP140L NCF1C BANK1

6.93e-051901005441770ce7b3c81f36f5b15b8e51794f736462457
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HGF CALD1 SERPINB9 C7 ADAMTSL2

7.11e-051911005a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-B|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BCL2A1 TLR1 NCF1B RECK ADAMTSL2

7.11e-051911005a4200717672e2358eb649eae2553f293b4fd8f7e
ToppCellAdult-Immune-monocyte-D175|Adult / Lineage, Cell type, age group and donor

ADCY7 SERPINB9 SLC24A4 TLR1 ENTPD1

7.11e-051911005cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

TANC2 CFTR MAGI3 DHCR24 MAP3K13

7.11e-051911005276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCF1 SERPINB9 PLAU NCF1C NCF1B

7.11e-0519110057d00796459f4ff0ab7f06a8379b2d34e76b078b2
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CALD1 SPOCK1 MAMDC2 PLAU C7

7.11e-0519110054e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HGF CALD1 SERPINB9 C7 ADAMTSL2

7.11e-0519110058f6d592edc32fdb901af30501d4360512334e8c2
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 VPS13C KCNMA1 PLAU C7

7.28e-05192100511088878043a6ff95ba1970361256a82e434b80a
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HGF CALD1 SPOCK1 MAMDC2 C7

7.28e-051921005c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP47 SAXO2 BBS9 LRGUK DNAH5

7.46e-051931005ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 SPOCK1 NEB ANGPTL4 C7

7.46e-0519310055bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP3 MAMDC2 ANGPTL4 C7 RECK

7.46e-051931005d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCellcontrol-Lymphoid-B_cell|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NCF1 BCL2A1 TLR1 ENTPD1 BANK1

7.65e-051941005a5284adca931a78b1c4592925c4860853ebd24f1
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D231|Adult / Lineage, Cell type, age group and donor

RCBTB2 LY6G6C KCNU1 ENTPD1 PLAU

7.65e-051941005800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCell(5)_Fibroblast-C_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

HGF CALD1 MAMDC2 C7 ADAMTSL2

7.65e-05194100529a72e565c19407bbd198cfbc2a78106fe830d05
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NCF1 ADCY7 SLC24A4 TLR1 ENTPD1

7.65e-051941005badefcec2af86cbcd97305f4843e84db0f3ebc66
ToppCellPBMC-Control-cDC_11|Control / Compartment, Disease Groups and Clusters

TANC2 ENPP3 SERPINB9 THRB SLC24A4

7.83e-05195100574d560ff0f47512441c305885c5c16272f711b8e
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

OLAH BCL2A1 PRKAG3 NCF1C NCF1B

7.83e-051951005d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HGF CALD1 SPOCK1 MAMDC2 C7

7.83e-051951005f54bc4454270ff06e85596f98199372b50d0179f
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

OLAH BCL2A1 PRKAG3 NCF1C NCF1B

7.83e-05195100519853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NCF1 ADCY7 MAMDC2 TLR1 KCNMA1

7.83e-05195100542bfdff88da1d07828c0ad65d412fb1752f0cee4
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HGF CALD1 SPOCK1 MAMDC2 C7

7.83e-0519510051236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCF1 ADCY7 TLR1 ENTPD1 KCNMA1

7.83e-05195100509df40ff9b493170861b3f6e57a942a834655b5c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DSCAM MAGI3 SYT7 PTK2B KCNMA1

7.83e-0519510052e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCF1 ADCY7 TLR1 ENTPD1 KCNMA1

7.83e-05195100534a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DSCAM CFTR XK LRGUK GUCA1A

8.03e-051961005a4cc02ea41479d24044bd2ca6441f85d683c0ca9
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

TANC2 WLS MYOF STK39 DNAH5

8.03e-05196100504f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellAdult-Immune-monocyte|Adult / Lineage, Cell type, age group and donor

ADCY7 SERPINB9 SLC24A4 TLR1 ENTPD1

8.03e-0519610053ef193c5180de3137daf886492e74fc574bc9767
ToppCellBronchial_Biopsy-Immune-Dendritic_cells|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

NCF1 BCL2A1 ADCY7 SERPINB9 ENTPD1

8.03e-051961005bd828596c5b3fd5e4156f555e532f3de99d32f92
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCF1 ADCY7 MGAT5 TLR1 KCNMA1

8.03e-051961005cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_ACKR1+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

WLS MYOF THRB ENTPD1 C7

8.22e-051971005143607d195c8aa2b94d995af0b2ef38582565611
ToppCellB_cells-Naive_B_cells_|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

BCL2A1 SERPINB9 MGAT5 ZBTB21 BANK1

8.22e-051971005fd5fdc5289d681d59ff22d72e4de6e74c6c7aac6
Diseaserheumatoid arthritis (implicated_via_orthology)

NCF1 KMT2C NCF1C NCF1B

5.55e-0812984DOID:7148 (implicated_via_orthology)
Diseasechronic granulomatous disease (implicated_via_orthology)

NCF1 NCF1C NCF1B

3.54e-075983DOID:3265 (implicated_via_orthology)
Diseaselethal congenital glycogen storage disease of heart (implicated_via_orthology)

PRKAG3 PRKAG1

3.27e-053982DOID:0090101 (implicated_via_orthology)
DiseaseWolff-Parkinson-White syndrome (implicated_via_orthology)

PRKAG3 PRKAG1

6.52e-054982DOID:384 (implicated_via_orthology)
Diseasewithdrawal disorder (implicated_via_orthology)

KCNU1 KCNMA1

1.08e-045982DOID:0060001 (implicated_via_orthology)
Diseasesubstance-related disorder (implicated_via_orthology)

KCNU1 KCNMA1

2.27e-047982DOID:303 (implicated_via_orthology)
DiseaseUterine leiomyoma

NUP107 THRB KCNMA1 RAP2C

2.45e-0491984HP_0000131
Diseaseprimary ovarian insufficiency (is_implicated_in)

BBS9 XPO5

3.02e-048982DOID:5426 (is_implicated_in)
DiseaseDiaphragmatic Hernia

CFTR THRB KCNMA1

3.46e-0441983C0019284
Diseaseectonucleoside triphosphate diphosphohydrolase 1 measurement

ENTPD1 C7

3.87e-049982EFO_0020342
DiseaseCiliopathies

CFTR BBS9 CPLANE1 DNAH5

5.04e-04110984C4277690
Diseasecholesteryl esters to total lipids in IDL percentage

PRKAG3 ANGPTL4 BANK1

6.22e-0450983EFO_0022247
Diseasedystonia (implicated_via_orthology)

KCNU1 KCNMA1

7.05e-0412982DOID:543 (implicated_via_orthology)
Diseasecholesterol to total lipids in IDL percentage

PRKAG3 ANGPTL4 BANK1

1.06e-0360983EFO_0022233
Diseasegrip strength measurement

KNTC1 DSCAM GRID1 FCSK ZBTB21 BANK1

1.12e-03350986EFO_0006941
Diseasetriglycerides to total lipids in IDL percentage

PRKAG3 ANGPTL4 BANK1

1.22e-0363983EFO_0022329
Diseasetriglycerides to phosphoglycerides ratio

PRKAG3 ANGPTL4 BANK1

1.52e-0368983EFO_0022327
Diseasecholesteryl esters to total lipids in very small VLDL percentage

PRKAG3 ANGPTL4 BANK1

1.72e-0371983EFO_0022259
Diseasetriglycerides to total lipids in small HDL percentage

PRKAG3 ANGPTL4 BANK1

1.79e-0372983EFO_0022336
Diseasefree cholesterol to total lipids in large LDL percentage

PRKAG3 ANGPTL4 BANK1

1.94e-0374983EFO_0022280
Diseasealpha-tocopherol measurement

HGF MGAT5

2.00e-0320982EFO_0007898
Diseasesusceptibility to mumps measurement

UBE2O KCNMA1 GABBR1

2.02e-0375983EFO_0008404
DiseaseST2 protein measurement

MGAT5 BANK1

2.20e-0321982EFO_0010599
Diseaseblood pressure

STK39 BANK1

2.42e-0322982EFO_0004325
DiseaseBronchiectasis

CFTR DNAH5

2.42e-0322982C0006267
DiseaseLeukemia, Myelocytic, Acute

HGF ADCY7 KMT2C FANCI

2.69e-03173984C0023467
Diseasesystemic scleroderma (is_implicated_in)

HGF BANK1

2.87e-0324982DOID:418 (is_implicated_in)
Diseasebreast cancer (implicated_via_orthology)

THRB PLAU

3.12e-0325982DOID:1612 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
KKVWCMKALEFPAGS

BANK1

246

Q8NDB2
AAPLWDSKKQSFVGM

PRKAG1

71

P54619
TSMNSSLPFCSWKKA

C9orf50

361

Q5SZB4
GQLKPMFHGIKWTCS

CAMTA1

216

Q9Y6Y1
PICKQSMGWSNLFTS

AGAP11

81

Q8TF27
PFLVNCKMTSDGGWT

ANGPTL4

211

Q9BY76
CSQFSWIMPGTIKEN

CFTR

491

P13569
MPKSLEIYKGSCNWE

LINC00269

1

Q8N2A0
AAPLWDSKKQSFVGM

PRKAG3

226

Q9UGI9
KSGWMTFLEVTGKIC

BCL2A1

151

Q16548
NISEWKCMAFAKFSP

DNHD1

1031

Q96M86
GTPSCSWKDLKTMTN

ADCY7

786

P51828
FTKEEWLKGMTSLQC

DCUN1D5

101

Q9BTE7
PVLKTQEKMVGCWFF

ARRDC4

176

Q8NCT1
IPNCSKPRWEKFFMV

SLC24A4

441

Q8NFF2
SSLKMLDVGKWPIFS

RCBTB2

21

O95199
QEWGCPFMETSAKSK

RAP2C

136

Q9Y3L5
IWNCMNSSLPGVFKK

RECK

81

O95980
TPGLQKFSKTASMLW

NUP107

196

P57740
PTKVVFMSLCKSFWD

MAMDC2

466

Q7Z304
GFFVAVLVKKSSMPW

NSUN2

421

Q08J23
PQFVQMLSWTSKICK

FANCI

1001

Q9NVI1
RSNSNKTMDPSCLKW

KAT7

591

O95251
VMKSVPTNGWKCKNC

KMT2C

421

Q8NEZ4
PTGQKVKMILDSQWC

MAGI3

596

Q5TCQ9
STGMFHWCAPKEIEK

KCNMA1

811

Q12791
MALFTPWKLSSQKLG

MGAT5

1

Q09328
MVWKKLGSRNFSSCP

SLC66A1

1

Q6ZP29
PKVRKCLANGSWTDM

GABBR1

76

Q9UBS5
CQMKAKRGWIPASFL

NCF1

196

P14598
SLVFTVHMWKSPGCQ

LMLN2

671

A0A1B0GTW7
VVRCWKMLSPGFDSS

ADAMTSL2

646

Q86TH1
MSASVSLQKLCPWFK

KNTC1

591

P50748
SGMFHWCKPTSLDKV

KCNU1

686

A8MYU2
KERQPCWSFPMGQKT

LRGUK

36

Q96M69
CLWFPFNSMSSGVKK

HGF

96

P14210
MKKFCAQPWEEIKTS

ENTPD1

386

P49961
NTPDKAMWGFACTVR

HECTD4

746

Q9Y4D8
QIRFMKKLDWSPSCF

BBS9

276

Q3SYG4
FCQMKAKRGWIPASF

NCF1B

196

A6NI72
FCQMKAKRGWIPASF

NCF1C

171

A8MVU1
KMWVFSNLRCGTPEE

LY6G6C

56

O95867
STCPDGFKILMKQTW

MAP3K13

376

O43283
LTSYWEQKKLMAPGC

FCSK

986

Q8N0W3
SSPKFSELVMKCLWR

CKAP5

1701

Q14008
SAWPSTMFKLGKDIT

IGSF1

1166

Q8N6C5
PFWNKRDDVLCSSMK

CPLANE1

526

Q9H799
TWDTLMPNINKLKTC

ENPP3

176

O14638
WKEQGSKTFMCTGRP

DHCR24

81

Q15392
FLCGSSLKWSPEMKN

C7

671

P10643
SLKWSPEMKNARCVQ

C7

676

P10643
WYKKFMTECPSGQLT

GUCA1A

21

P43080
MASLNCIRKSTKPWN

GRID1

346

Q9ULK0
STFSCIMQKWGGKRE

HAS3

181

O00219
LPWNGEFTVMEKKCE

CST8

126

O60676
FAVCMWEILSFGKQP

PTK2B

611

Q14289
WNLVMTRNCFPTKST

FAM86C2P

146

A6NEL3
NIKFKPSIGSMCWVI

PRSS46P

151

E5RG02
KNPEATFKLICFPWM

OLAH

21

Q9NV23
SMVFDSPTIGKFWKS

CFAP47

811

Q6ZTR5
LEKSCTMPSWQESLK

DNAH5

3341

Q8TE73
LSPKSWMDADLACQK

REG3G

56

Q6UW15
AVKWMKDSNGTPSLV

DSCAM

1316

O60469
DLTQMQTFWKDLKPC

SYT7

246

O43581
TTKMLCAADPQWKTD

PLAU

356

P00749
SQTLKAMVQAWPFTC

PRAME

66

P78395
MLGPAKETNIAVFWC

TMEM161A

126

Q9NX61
FKKKGCTWGPNSIQM

MAP3K21

586

Q5TCX8
GKSCSPKMRLDDFWS

MKLN1

606

Q9UL63
ICTVSMSQDFGWNKK

SLC17A9

46

Q9BYT1
IKPWQSQKSSMDSCL

TANC2

211

Q9HCD6
MKAGSINVWNICPLF

SLC6A8

116

P48029
KCIQTEDGKWFTPME

SP140L

326

Q9H930
KGDCSWTKSLLSLNM

TLR1

416

Q15399
NIKSMWEKGNVFSSP

CALD1

711

Q05682
VKTCKWLFETQPMES

XIRP2

916

A4UGR9
WSLRVCFGMLPKSKT

PTRH2

31

Q9Y3E5
FCEMVSPTPKWFVKA

TLCD5

181

Q6ZRR5
ASLWPCEKCGKMFTV

ZBTB21

906

Q9ULJ3
LKLGFGKSMPTNCVW

SPEN

506

Q96T58
LTFEKLTAWTKPDCM

SERPINB9

246

P50453
FPSGLKDMLKTAWLQ

ROM1

311

Q03395
KSGWMTFLEVTGKIC

ST20

26

Q9HBF5
TFSSGPSDKMKWCLR

SPOPL

56

Q6IQ16
SSPWLGKVQKMVSFN

SPOCD1

1026

Q6ZMY3
MTENGLTAWDKPKHC

THRB

6

P10828
KTPDWLVTMENGFRC

FAM170A

216

A1A519
TCMVKWFKLRPSGDD

UBE2O

616

Q9C0C9
ILPICKDSLGWMFNK

SPOCK1

241

Q08629
CRLDPKTSFQMAGEW

XPO5

451

Q9HAV4
PCSLFMEKCTWASGK

VPS13C

2176

Q709C8
GKSIMKEDFPAWESC

SAXO2

281

Q658L1
SLMTKEISSVPCWQF

PRKDC

3481

P78527
IWPRIDQKSCFKSMI

SEPSECS

166

Q9HD40
STQPTHSWKVGDKCM

SMNDC1

66

O75940
EKSKPMFFCHRWSIG

ZFAND1

176

Q8TCF1
TKVWFAMKTFLTPSI

WLS

231

Q5T9L3
NKVRKTFVGTPCWMA

STK39

226

Q9UEW8
NMFCWSAVQLKIDSP

XK

291

P51811
MEKLKWTSPFTCHRV

VWA5B1

1076

Q5TIE3
FLWFTNPCKTMKFIV

MYOF

2006

Q9NZM1
KWKTKFSSPVDMLGV

NEB

3081

P20929