Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoDecreased glucose-6-phosphate dehydrogenase level in blood

G6PD CASK

1.32e-052192HP:0410179
HumanPhenoAbnormal glucose-6-phosphate dehydrogenase level in blood

G6PD CASK

1.32e-052192HP:0410177
HumanPhenoAbnormal circulating glucose-6-phosphate dehydrogenase concentration

G6PD CASK

1.32e-052192HP:0410176
HumanPhenoFava bean-induced hemolytic anemia

G6PD CASK

3.95e-053192HP:0004814
MousePhenoabnormal ependyma morphology

SOX2 CFAP54 LPO MKS1

1.05e-0546424MP:0002653
DomainZinc_finger_PHD-type_CS

PHF1 KDM5C CHD3

8.32e-0465533IPR019786
DomainPHD

PHF1 KDM5C CHD3

1.26e-0375533PF00628
DomainSynaptotagmin

SYT1 SYT5

1.45e-0320532IPR001565
DomainZnf_PHD-finger

PHF1 KDM5C CHD3

1.47e-0379533IPR019787
DomainPHD

PHF1 KDM5C CHD3

2.06e-0389533SM00249
DomainZnf_PHD

PHF1 KDM5C CHD3

2.20e-0391533IPR001965
DomainZF_PHD_2

PHF1 KDM5C CHD3

2.48e-0395533PS50016
DomainZF_PHD_1

PHF1 KDM5C CHD3

2.56e-0396533PS01359
Domain-

HEATR6 ARMC3 ZER1 TNPO3

3.61e-032225341.25.10.10
DomainMit_carrier

SLC25A21 SLC25A17

3.71e-0332532IPR002067
DomainARM_REPEAT

ARMC3 ZER1

5.75e-0340532PS50176
DomainARM

ARMC3 ZER1

5.75e-0340532SM00185
DomainARM-like

HEATR6 ARMC3 ZER1 TNPO3

7.18e-03270534IPR011989
DomainPDZ

AHNAK LRRC7 CASK

7.49e-03141533PF00595
DomainArmadillo

ARMC3 ZER1

7.87e-0347532IPR000225
DomainZnf_FYVE_PHD

PHF1 KDM5C CHD3

8.40e-03147533IPR011011
DomainPDZ

AHNAK LRRC7 CASK

8.55e-03148533SM00228
Domain-

AHNAK LRRC7 CASK

8.87e-031505332.30.42.10
DomainPDZ

AHNAK LRRC7 CASK

9.03e-03151533PS50106
DomainPDZ

AHNAK LRRC7 CASK

9.20e-03152533IPR001478
DomainSOLCAR

SLC25A21 SLC25A17

9.93e-0353532PS50920
Pubmed

Synaptotagmin 9 Modulates Spontaneous Neurotransmitter Release in Striatal Neurons by Regulating Substance P Secretion.

SYT1 SYT5

7.63e-06356236732068
Pubmed

Synaptotagmin IV regulates glial glutamate release.

SYT1 SYT5

7.63e-06356215197251
Pubmed

Synaptotagmin-1, -2, and -9: Ca(2+) sensors for fast release that specify distinct presynaptic properties in subsets of neurons.

SYT1 SYT5

7.63e-06356217521570
Pubmed

Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11.

SOX2 STK11

7.63e-06356234385181
Pubmed

Differential expression of paralog RNA binding proteins establishes a dynamic splicing program required for normal cerebral cortex development.

SOX2 LRRC7 CASK

1.26e-052856338324473
Pubmed

A Synaptotagmin Isoform Switch during the Development of an Identified CNS Synapse.

SYT1 SYT5

1.52e-05456227210552
Pubmed

Sox2 cooperates with Lkb1 loss in a mouse model of squamous cell lung cancer.

SOX2 STK11

2.54e-05556224953650
Pubmed

Phospholipid composition dependence of Ca2+-dependent phospholipid binding to the C2A domain of synaptotagmin IV.

SYT1 SYT5

3.80e-0565628626542
Pubmed

AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair.

STK11 AMER1 SOCS5 CFAP46

4.45e-0512156431900314
Pubmed

The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment.

SOX2 STK11

5.32e-05756230332632
Pubmed

Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.

SOX2 STK11

7.09e-05856224794706
Pubmed

Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea.

SOX2 SYT1

9.10e-05956229059194
Pubmed

Distinct developmental expression of synaptotagmin I and IX in the mouse brain.

SYT1 SYT5

9.10e-05956216407767
Pubmed

Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin.

SYT1 SYT5

9.10e-0595628901523
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

PHF1 AHNAK BOD1L1 CHD3 BIRC6 TASOR

1.07e-0446956627634302
Pubmed

Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion.

SYT1 SYT5

1.14e-04105629914469
Pubmed

High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1.

SYT1 CASK

1.39e-041156219523119
Pubmed

SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms.

SYT1 SYT5

1.39e-041156210734137
Pubmed

Neuronal cell adhesion molecule (NrCAM) is expressed by sensory cells in the cochlea and is necessary for proper cochlear innervation and sensory domain patterning during development.

SOX2 SYT1

1.39e-041156229536590
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-8 ERVK-9

1.66e-041256214557543
Pubmed

The finished DNA sequence of human chromosome 12.

CFAP54 PHB2 LRCOL1

1.92e-046956316541075
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

KDM5C AHNAK PHB2 BOD1L1 CHD3 NNMT G6PD POLR3C

2.09e-04101456832416067
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

COL12A1 AHNAK BOD1L1 ERMP1 OSGEP BIRC6 G6PD TNPO3 GNS

2.12e-04129756933545068
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

UBR2 PHB2 ZER1 CHD3 OSGEP TNPO3

2.14e-0453356625544563
Pubmed

Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins.

COL12A1 SYT1

2.29e-041456228511701
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

SOX2 STK11 AMER1 SOCS5 SYT1 BOD1L1 CHD3 TASOR

3.27e-04108456811544199
Pubmed

Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation.

KDM5C G6PD

3.41e-041756219571810
Pubmed

A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.

SOX2 CHD3

3.41e-041756227806305
Pubmed

Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons.

SOX2 SYT1

3.83e-041856226302206
Pubmed

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.

AHNAK LPO BOD1L1 TASOR

4.20e-0421756434048709
Pubmed

Scrg1, a novel protein of the CNS is targeted to the large dense-core vesicles in neuronal cells.

SYT1 SYT5

4.28e-041956214622145
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

STK11 AMER1 ARMC3 AHNAK PHB2 BOD1L1 CHD3 TASOR CFAP46

4.61e-04144256935575683
Pubmed

FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation.

SOX2 LPO

5.76e-042256237838739
Pubmed

RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion.

SOX2 SOCS5

7.46e-042556229361558
Pubmed

Positioning of five genes (CASK, ARX, SAT, IMAGE cDNAs 248928 and 253949) from the human X chromosome short arm with respect to evolutionary breakpoints on the mouse X chromosome.

KDM5C CASK

8.07e-042656210920247
Pubmed

Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death.

SOX2 SYT1

8.07e-042656226857994
Pubmed

Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.

SYT1 CASK

8.07e-042656217124501
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

SLC4A1AP AHNAK PHB2 SYT1 BOD1L1 CHD3 TASOR

8.23e-0495456736373674
Pubmed

Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins.

SOX2 SYT1

1.01e-032956228794184
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

SOX2 BOD1L1 CHD3 TNPO3

1.12e-0328256423667531
Pubmed

STK11 is required for the normal program of ciliated cell differentiation in airways.

SOX2 STK11

1.15e-033156231636950
Pubmed

Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.

SOX2 MKS1

1.30e-033356230626697
Pubmed

Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.

PHB2 LRRC7 BIRC6 SLC25A17

1.33e-0329656434186245
Pubmed

Radial glia require PDGFD-PDGFRβ signalling in human but not mouse neocortex.

SOX2 ABHD3

1.38e-033456225391964
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

UBR2 SLC4A1AP AHNAK BCAR1 BIRC6 G6PD CASK

1.42e-03104956727880917
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

UBR2 APOO PDPK1 ZER1 BIRC6

1.43e-0351556531617661
Pubmed

Identification of the BRD1 interaction network and its impact on mental disorder risk.

PHB2 CHD3

1.46e-033556227142060
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

AMER1 AHNAK BIRC6 TASOR MKS1 CASK

1.53e-0377756635844135
Cytoband17q23.1

HEATR6 LPO

1.73e-041656217q23.1
GeneFamilySynaptotagmins

SYT1 SYT5

4.86e-0417352765
GeneFamilyPHD finger proteins

PHF1 KDM5C CHD3

6.96e-049035388
GeneFamilyPDZ domain containing

AHNAK LRRC7 CASK

3.13e-031523531220
GeneFamilyCollagens

COL4A4 COL12A1

3.57e-0346352490
GeneFamilySolute carriers

SLC5A11 SLC25A21 SLC35D2 SLC25A17

6.88e-03395354752
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ARMC3 ANKEF1 SYT5 CFAP61 CFAP46

2.92e-0815154681cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ARMC3 ANKEF1 SYT5 CFAP61 CFAP46

2.92e-081515469cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP54 ARMC3 ERMP1 CFAP61 PLEKHH2 AGBL3

8.58e-081815466a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ARMC3 SYT5 CFAP61 CFAP46

1.00e-06148545d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ARMC3 SYT5 CFAP61 CFAP46

1.00e-06148545c8e93b87212f55774223caa385859c566fa1981f
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ARMC3 ANKEF1 SYT5 CFAP46

1.22e-0615454558072ce422d09f2de602580325eaac6c4ec6c136
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ARMC3 ANKEF1 SYT5 CFAP46

1.22e-061545459ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ARMC3 ANKEF1 CFAP61 CFAP46

1.26e-061555455f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ARMC3 ANKEF1 CFAP61 CFAP46

1.26e-061555450944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP54 ARMC3 CFAP61 PLEKHH2 AGBL3

2.28e-06175545284fdc7a9d303636a637041846850d19d114861a
ToppCellP07-Epithelial-airway_epithelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX2 CFAP54 SYT5 CFAP61 CFAP46

2.91e-06184545a5e7af3392e9d6ddad0397f1eeb6b91ed1107cc2
ToppCellP07-Epithelial-airway_epithelial_cell-club_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX2 CFAP54 SYT5 CFAP61 CFAP46

2.91e-06184545ab469b9e06212462cbe2e4db8775c6778db855e6
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX2 CFAP54 ARMC3 CFAP61 CFAP46

2.99e-061855453e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

CFAP54 ARMC3 CFAP61 CFAP46

3.38e-051515448216462e723fec2797387929dde095370947e10a
ToppCellCiliated_cells-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

SOX2 CFAP54 ARMC3 CFAP46

3.38e-051515449d03ce73af15ef40c592d19b36aff46bebc14c40
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SOX2 CFAP54 SYT5 CFAP46

3.56e-05153544fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SOX2 CFAP54 SYT5 CFAP46

3.56e-051535442482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ARMC3 CFAP61 CFAP46

3.65e-051545447556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ARMC3 CFAP61 CFAP46

3.65e-051545444e3bc24043144143842627cacf6f90dda2228910
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ARMC3 ANKEF1 CFAP46

4.67e-05164544e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SOX2 CFAP54 ARMC3 CFAP46

4.78e-0516554482530f96aaefe28a13bad0474bbad043f127a86c
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SOX2 CFAP54 ARMC3 CFAP46

4.78e-051655440c714e852f912b5749de4cb0895406673979b2e6
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 ARMC3 CFAP61 CFAP46

5.25e-05169544fba841664939c771881ba97f14ef1df6635c04ff
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SOX2 CFAP54 ARMC3 CFAP46

5.88e-05174544f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SOX2 CFAP54 ARMC3 CFAP46

6.01e-05175544c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP54 ARMC3 CFAP61 CFAP46

6.42e-05178544de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL4A4 GUCY2C SYT1 CD180

6.85e-051815440bc58c8942491e7ee5b858c5742770df7677532f
ToppCellP03-Epithelial-airway_epithelial_cell-club_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX2 CFAP54 CFAP61 CFAP46

6.85e-0518154460a91587c59029a34e7bec1255083337fe21b72a
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP54 ARMC3 CFAP61 CFAP46

6.85e-05181544dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellP03-Epithelial-airway_epithelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX2 CFAP54 CFAP61 CFAP46

6.85e-051815441ea21d860d4d7abab3e21e130a16d044006656ee
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

CFAP54 ARMC3 CFAP61 CFAP46

7.00e-051825447ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

CFAP54 ARMC3 CFAP61 CFAP46

7.00e-05182544fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP54 ARMC3 CFAP61 CFAP46

7.00e-05182544587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP54 ARMC3 CFAP61 CFAP46

7.00e-05182544adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

SOX2 CFAP54 ARMC3 CFAP46

7.00e-05182544e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell18-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

CFAP54 ARMC3 SYT5 CFAP46

7.15e-05183544a75cda2131755931117c387f2e0ae3394efa8e80
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 LRCOL1 TEX11 NNMT

7.15e-05183544269afec240a756eec3bbae5f30ec784281af3433
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP54 ARMC3 CFAP61 CFAP46

7.30e-051845445daff849625f2f41d56615569c0ed59cd733b34c
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

CFAP54 ARMC3 CFAP61 CFAP46

7.45e-0518554430f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

CFAP54 ARMC3 CFAP61 CFAP46

7.45e-0518554418a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCiliated_cells-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

SOX2 CFAP54 ARMC3 CFAP46

7.45e-05185544d77ca57b02125a3a57a37f4aed20c89803b7d551
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP54 ARMC3 CFAP61 CFAP46

7.77e-051875449e10ed56090d82589bc457788282f664b70ace4b
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A4 COL12A1 PLEKHH2 NNMT

7.77e-051875444ea486991f66c29728d127171a07b81404ec0b78
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

CFAP54 ARMC3 CFAP61 CFAP46

7.77e-05187544f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellControl-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

COL4A4 COL12A1 AHNAK SYT1

7.77e-051875443a032432f780525f4f4c2a358897d9989b1ecae7
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

CFAP54 ARMC3 CFAP61 CFAP46

7.93e-0518854434b11f72ca73153d02edcd09b38983ad1a504659
ToppCelltumor_Lung-Epithelial_cells-tS3|tumor_Lung / Location, Cell class and cell subclass

SOX2 ARMC3 CFAP61 CFAP46

7.93e-0518854426326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

CFAP54 ARMC3 CFAP61 CFAP46

7.93e-0518854461a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP54 ARMC3 CFAP61 CFAP46

7.93e-051885442b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellCOPD-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

COL4A4 COL12A1 AHNAK SYT1

8.10e-0518954414e8e57e4db336fbef005270647983b4edf407c0
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP54 ARMC3 CFAP61 CFAP46

8.10e-0518954468a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

SOX2 CFAP54 ARMC3 CFAP46

8.10e-05189544dc440015949a768188c67661b6be63b1ead1a0f0
ToppCellControl-Epithelial-Ciliated|Control / Disease state, Lineage and Cell class

CFAP54 ARMC3 CFAP61 CFAP46

8.10e-05189544c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

CFAP54 ARMC3 CFAP61 CFAP46

8.10e-05189544b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

CFAP54 ARMC3 CFAP61 CFAP46

8.10e-0518954427329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP54 ARMC3 CFAP61 CFAP46

8.10e-051895443e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellCiliated|World / shred by cell class for parenchyma

SOX2 CFAP54 ARMC3 CFAP46

8.10e-05189544711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCellEpithelial-D_(Ciliated)|World / shred on cell class and cell subclass (v4)

SOX2 CFAP54 SYT5 CFAP46

8.10e-051895440bf560b595c7a8450a46bc821b742b67965bd9f9
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SOX2 CFAP54 ARMC3 CFAP46

8.26e-05190544a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP54 ARMC3 CFAP61 CFAP46

8.43e-05191544e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellLAM-Epithelial-AT1|Epithelial / Condition, Lineage and Cell class

COL4A4 COL12A1 AHNAK PLEKHH2

8.43e-051915443457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A4 CFAP54 ERMP1 PLEKHH2

8.43e-05191544d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellcritical-Lymphoid-B_cell|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

COL4A4 GUCY2C SYT1 CD180

8.43e-051915440716cfaeb11d9c90c18fa8f9d50c9c6fb5182848
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP54 ARMC3 CFAP61 CFAP46

8.43e-051915449d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP54 ARMC3 CFAP61 CFAP46

8.43e-051915441c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellnormal_Lung-Epithelial_cells-Ciliated|normal_Lung / Location, Cell class and cell subclass

SOX2 CFAP54 ARMC3 CFAP46

8.60e-05192544097a13121820ab4e5cd2365600efccf5ea4ce8c3
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP54 ARMC3 CFAP61 CFAP46

8.60e-05192544d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP54 ARMC3 CFAP61 CFAP46

8.60e-05192544eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

CFAP54 ARMC3 CFAP61 CFAP46

8.60e-05192544354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellPND03-Epithelial-Epithelial_Airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX2 CFAP54 SYT5 CFAP46

8.60e-051925442d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCellVE-naiveBc-|VE / Condition, Cell_class and T cell subcluster

COL4A4 GUCY2C SYT1 CD180

8.60e-05192544bca2aec4811627225fccd92abe2f3b1ba729c9ce
ToppCellVE-naiveBc|VE / Condition, Cell_class and T cell subcluster

COL4A4 GUCY2C SYT1 CD180

8.60e-0519254487cdda9a170f6f2fa56d0ed1d3fd2f93bfe09aa1
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP54 ARMC3 CFAP61 CFAP46

8.78e-051935440e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

COL4A4 COL12A1 PLEKHH2 NNMT

8.78e-05193544dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SOX2 CFAP54 ARMC3 CFAP46

8.78e-05193544ea345d34440b25f65358a53dc72831998d1c3620
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

COL4A4 GUCY2C SYT1 CD180

8.78e-05193544437ae3b10d169bb371f7b92d57a77f43e3f8d64d
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP54 ARMC3 CFAP61 CFAP46

8.78e-05193544ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL4A4 GUCY2C SYT1 CD180

8.78e-0519354494b5a4a4e9faaa95cb72907a2f0497429c72e516
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL4A4 GUCY2C SYT1 CD180

8.78e-051935442416b39e18ce0c7016c2351f79bf1b2ecc183a98
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

COL4A4 COL12A1 PLEKHH2 NNMT

8.95e-05194544d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL4A4 GUCY2C CD180 NNMT

8.95e-05194544cbc4b6422777117e4123804168c23f19d1b79486
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP54 ARMC3 CFAP61 CFAP46

8.95e-05194544958e648138676d46698090b4046cb484083ae449
ToppCellremission-B_intermediate|World / disease stage, cell group and cell class

COL4A4 GUCY2C SYT1 CD180

8.95e-0519454478556b60c84c7bbffa1c8bf8684b3c427512da44
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

COL4A4 COL12A1 PLEKHH2 NNMT

8.95e-05194544014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

SOX2 CFAP54 ARMC3 CFAP46

8.95e-0519454443be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellCOVID-19_Convalescent-Lymphoid_B-B_intermediate|COVID-19_Convalescent / Disease group, lineage and cell class

COL4A4 GUCY2C SYT1 CD180

9.13e-05195544b213f19dad4c8d5a6bf20cadb1135fb2bb0b40ee
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A4 COL12A1 SYT1 LRCOL1

9.13e-05195544803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

CFAP54 ARMC3 CFAP61 CFAP46

9.13e-0519554421dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

COL4A4 COL12A1 PLEKHH2 NNMT

9.13e-05195544f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A4 COL12A1 SYT1 LRCOL1

9.13e-051955444f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellremission-B_intermediate|remission / disease stage, cell group and cell class

COL4A4 GUCY2C SYT1 CD180

9.13e-05195544ee14d00eb5800fadd57c2304e9461534d8668674
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

COL4A4 COL12A1 PLEKHH2 NNMT

9.13e-05195544a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell(05)_Ciliated|World / shred by cell type and Timepoint

CFAP54 ARMC3 SYT5 CFAP61

9.50e-05197544fee3cd16af8eea697cd64e8f64af505aaa2ac4b0
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP54 ARMC3 SYT5 CFAP46

9.50e-051975446e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARMC3 SYT5 CFAP61 CFAP46

9.69e-05198544f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCellLAM-Endothelial-LymEndo|Endothelial / Condition, Lineage and Cell class

AHNAK BCAR1 NNMT CASK

9.69e-05198544ba64b1c95dfaa995045239d412e725596f6c482e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-cortical_neurons_1|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

SYT1 SYT5 LRRC7 CHD3

9.69e-05198544d81f35c0066558ff96dd06f58fca72cd82e681e8
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

COL4A4 COL12A1 SYT1 PLEKHH2

9.69e-05198544bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP54 ARMC3 CFAP61 CFAP46

9.88e-05199544542ec45c931b40738df1f3777b00c83be33a514a
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A4 CYP7B1 PLEKHH2 NNMT

9.88e-051995440cdbedf09ec72734b86ddab3fec562e066afed92
DiseaseANEMIA, NONSPHEROCYTIC HEMOLYTIC, DUE TO G6PD DEFICIENCY

G6PD CASK

3.29e-062542C2720289
DiseaseAnemia, nonspherocytic hemolytic, due to G6PD deficiency

G6PD CASK

3.29e-062542cv:C2720289
DiseaseANEMIA, NONSPHEROCYTIC HEMOLYTIC, DUE TO G6PD DEFICIENCY

G6PD CASK

3.29e-062542300908
Diseasecongenital myasthenic syndrome 7 (implicated_via_orthology)

SYT1 SYT5

1.97e-054542DOID:0110659 (implicated_via_orthology)
Diseaseneuromuscular junction disease (implicated_via_orthology)

SYT1 SYT5

3.28e-055542DOID:439 (implicated_via_orthology)
DiseasePARTINGTON X-LINKED MENTAL RETARDATION SYNDROME

KDM5C CASK

9.14e-058542C0796250
Diseasecongenital myasthenic syndrome (implicated_via_orthology)

SYT1 SYT5

3.88e-0416542DOID:3635 (implicated_via_orthology)
Diseaseprostate specific antigen measurement

SLC25A21 SLC35D2 CHD3 TEX11

3.94e-04188544EFO_0004624
Diseasehealth study participation

SLC5A11 PHF1 CYP7B1 BIRC6

4.52e-04195544EFO_0010130
DiseaseMalignant Neoplasms

STK11 BIRC6 G6PD

1.68e-03128543C0006826

Protein segments in the cluster

PeptideGeneStartEntry
VEMGKKIPLKGTDLY

AGBL3

741

Q8NEM8
PIPAGYKATGKMKIF

CFAP54

2146

Q96N23
LIPMYKGAKIQGGIL

CFAP61

1031

Q8NHU2
PKLVKGMAGGKYRSF

BIRC6

1206

Q9NR09
PGNRLKILVGMYDKK

BCAR1

56

P56945
KILVGMYDKKPAGPG

BCAR1

61

P56945
RALEMGIKYLKKFGP

CFAP46

961

Q8IYW2
CLYKGEKGIKGIPGM

COL4A4

266

P53420
LLNYLGKIGSKTPLM

ABHD3

226

Q8WU67
VGLHLKGPKMKGDYD

AHNAK

1456

Q09666
AMKLFGGKKGICTLP

AMER1

56

Q5JTC6
FVLGSYGPKKKEKGM

ANKEF1

406

Q9NU02
DLAKYVAEKMGGKIP

ARMC3

746

Q5W041
KGLPSGMKGLNLLKK

CD180

311

Q99467
MGVVLYLGKKFLQPK

ERMP1

426

Q7Z2K6
IMGASGDLAKKKIYP

G6PD

36

P11413
IIMCGGPEFLYKLKG

GUCY2C

246

P25092
LLLGSMAGYGPQKKL

LRCOL1

16

A6NCL2
AGLLGDKKYIMGPKL

FAXC

271

Q5TGI0
EGILALYKGLLPKIM

SLC25A21

261

Q9BQT8
LFEGIIKGKYKMNPR

CASK

226

O14936
ILFMYGKPKSKDPLG

OR13C7

256

P0DN81
SKIKKLVYPPGFMGL

APOO

131

Q9BUR5
VLPGSIGKLKMLVYL

LRRC7

221

Q96NW7
FGIMGLYKGLEAKLL

SLC25A17

261

O43808
KMLAKKLLGLYGTPD

LPO

591

P22079
LLKPGGFLVIMDALK

NNMT

186

P40261
KYLPELLGNTGLLMK

HEATR6

156

Q6AI08
RGKKLVELPYTVKGM

OSGEP

186

Q9NPF4
KMLGEALSKNPGYIK

PHB2

236

Q99623
KPTMKGLLTKVKHGY

PLEKHH2

811

Q8IVE3
LGGLKLKANLKMEAY

BOD1L1

2661

Q8NFC6
AIKKIPYKGGNTMTG

COL12A1

206

Q99715
GKKMAPLKIKLGLLG

CHD3

286

Q12873
LGGMTPLKKTKALIG

GNS

61

P15586
RGKKLKCYLMPFGTG

CYP7B1

431

O75881
LGMKLSLPYGLKGLD

PHF1

161

O43189
KKMDVGGLSDPYVKI

SYT1

301

P21579
LKKMDVGGLSDPYVK

SYT5

266

O00445
TKTLMKKDKYTLPGG

SOX2

116

P48431
KQKMDPKELGKYGVL

SLC35D2

191

Q76EJ3
LYKLGPKLAPGMTEI

SOCS5

296

O75159
LILKMGPVDKRKGLF

PDPK1

456

O15530
KGGALMAAYLKVLPL

SLC5A11

306

Q8WWX8
KRAKLIGKYLMGDLL

STK11

41

Q15831
KIMTKRGYIPGKGLG

ERVK-9

896

P63128
KYMGLKLGPALKLSY

SCMH1

636

Q96GD3
GKIKSIYDPMGVKSL

TASOR

246

Q9UK61
QKIMTKRGYIPGKGL

ERVK-9

116

P63127
KYCPLLIKEGGMPLL

ZER1

716

Q7Z7L7
DMYLVPKLSLIGKGK

POLR3C

186

Q9BUI4
IMADLGPYKKLGYKK

MKS1

206

Q9NXB0
SPGLFLKMKILLKGE

TEX11

301

Q8IYF3
PVLGYLMKGLCEKPL

TNPO3

501

Q9Y5L0
QKIMTKRGYIPGKGL

ERVK-8

116

P63122
KKPGLTGRGMYELKP

UBR2

821

Q8IWV8
PELKKLQIYGAGPKM

KDM5C

231

P41229
KKLTLPLFGAMKGGS

SLC4A1AP

601

Q9BWU0