Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmacrophage colony-stimulating factor receptor activity

MST1R CSF1R

1.18e-052692GO:0005011
GeneOntologyBiologicalProcessanterograde synaptic vesicle transport

TRIM46 AP3M2 AP3M1

5.05e-0522683GO:0048490
GeneOntologyBiologicalProcesssynaptic vesicle cytoskeletal transport

TRIM46 AP3M2 AP3M1

5.05e-0522683GO:0099514
GeneOntologyBiologicalProcesssynaptic vesicle transport along microtubule

TRIM46 AP3M2 AP3M1

5.05e-0522683GO:0099517
DomainATP_Ca_trans_C

ATP2B1 ATP2B2

7.12e-054652IPR022141
DomainATP_Ca_trans_C

ATP2B1 ATP2B2

7.12e-054652PF12424
DomainP-type_ATPase_IIB

ATP2B1 ATP2B2

7.12e-054652IPR006408
DomainClathrin_mu_CS

AP3M2 AP3M1

1.77e-046652IPR018240
DomainCLAT_ADAPTOR_M_1

AP3M2 AP3M1

1.77e-046652PS00990
DomainCLAT_ADAPTOR_M_2

AP3M2 AP3M1

1.77e-046652PS00991
DomainClathrin_mu

AP3M2 AP3M1

5.27e-0410652IPR001392
DomainAdap_comp_sub

AP3M2 AP3M1

6.43e-0411652PF00928
DomainClathrin_sm-chain_CS

AP3M2 AP3M1

7.70e-0412652IPR000804
DomainCarboxyPept_regulatory_dom

CPXM1 CPN1

9.08e-0413652IPR014766
DomainMHD

AP3M2 AP3M1

9.08e-0413652PS51072
Domain-

CPXM1 CPN1

9.08e-04136522.60.40.1120
DomainMHD

AP3M2 AP3M1

9.08e-0413652IPR028565
DomainConA-like_dom

TRIM46 FAT4 FAT2 SVEP1 RYR1

9.88e-04219655IPR013320
DomainHEAT

STK36 MTOR IPO13

1.08e-0358653IPR000357
Domain-

ATP2B1 ATP2B2

1.39e-03166521.20.1110.10
DomainSulfatase_CS

ARSB ARSI

1.39e-0316652IPR024607
DomainAP_mu_sigma_su

AP3M2 AP3M1

1.39e-0316652IPR022775
DomainClat_adaptor_s

AP3M2 AP3M1

1.39e-0316652PF01217
DomainATPase_P-typ_TM_dom

ATP2B1 ATP2B2

1.39e-0316652IPR023298
DomainSULFATASE_1

ARSB ARSI

1.57e-0317652PS00523
DomainATPase_P-typ_cation-transptr_C

ATP2B1 ATP2B2

1.57e-0317652IPR006068
DomainCation_ATPase_C

ATP2B1 ATP2B2

1.57e-0317652PF00689
DomainCarboxyPept-like_regulatory

CPXM1 CPN1

1.57e-0317652IPR008969
DomainSULFATASE_2

ARSB ARSI

1.57e-0317652PS00149
DomainSulfatase

ARSB ARSI

1.76e-0318652PF00884
DomainZn_pept

CPXM1 CPN1

1.76e-0318652SM00631
DomainCation_ATPase_N

ATP2B1 ATP2B2

1.76e-0318652PF00690
DomainCation_ATPase_N

ATP2B1 ATP2B2

1.76e-0318652SM00831
DomainSulfatase_N

ARSB ARSI

1.76e-0318652IPR000917
DomainATPase_P-typ_cation-transptr_N

ATP2B1 ATP2B2

1.96e-0319652IPR004014
DomainCARBOXYPEPT_ZN_2

CPXM1 CPN1

1.96e-0319652PS00133
DomainCARBOXYPEPT_ZN_1

CPXM1 CPN1

2.18e-0320652PS00132
DomainPeptidase_M14

CPXM1 CPN1

2.88e-0323652PF00246
DomainPeptidase_M14

CPXM1 CPN1

2.88e-0323652IPR000834
DomainPAS-assoc_C

PER3 KCNH5

3.13e-0324652IPR000700
DomainPAC

PER3 KCNH5

3.67e-0326652IPR001610
DomainPAC

PER3 KCNH5

3.67e-0326652SM00086
DomainPAC

PER3 KCNH5

3.67e-0326652PS50113
DomainLongin-like_dom

AP3M2 AP3M1

4.25e-0328652IPR011012
DomainhEGF

FAT4 SVEP1

4.25e-0328652PF12661
Pubmed

Parasite-induced IFN-γ regulates host defense via CD115 and mTOR-dependent mechanism of tissue-resident macrophage death.

IFNGR2 CSF1R MTOR

7.79e-08570338377133
Pubmed

A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.

FAT2 CSF1R ARSI

6.50e-07970319966810
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

MTOR HECTD4 AP3M2 ARFGEF1 DNMBP GAA

1.94e-0618370631932471
Pubmed

Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease.

MTOR GAA

3.99e-06270220554235
Pubmed

Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.

UBR1 MGMT

3.99e-06270226183928
Pubmed

Insulin inhibition of apolipoprotein B mRNA translation is mediated via the PI-3 kinase/mTOR signaling cascade but does not involve internal ribosomal entry site (IRES) initiation.

MTOR APOB

3.99e-06270217698027
Pubmed

Lethal multiple pterygium syndrome, large cystic hygroma, and cleft palate: Rare and severe fetal presentations of RYR1- and NEB-related congenital myopathies.

NEB RYR1

3.99e-06270238520674
Pubmed

Plasma Membrane Calcium ATPase-Neuroplastin Complexes Are Selectively Stabilized in GM1-Containing Lipid Rafts.

ATP2B1 ATP2B2

1.20e-05370234948386
Pubmed

Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory modulation.

MGMT MTOR

1.20e-05370224718901
Pubmed

Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).

ATXN1 MTOR

1.20e-05370227466200
Pubmed

Trafficking of presynaptic PMCA signaling complexes in mouse photoreceptors requires Cav1.4 α1 subunits.

ATP2B1 ATP2B2

1.20e-05370222183401
Pubmed

Protein kinase C phosphorylates the carboxyl terminus of the plasma membrane Ca(2+)-ATPase from human erythrocytes.

ATP2B1 ATP2B2

1.20e-0537021827443
Pubmed

Plasma membrane Ca2+ ATPase isoform 2b interacts preferentially with Na+/H+ exchanger regulatory factor 2 in apical plasma membranes.

ATP2B1 ATP2B2

1.20e-05370211786550
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MST1R STK36 ABR ZBED4 CTC1 MTOR HECTD4 PAPLN DNMBP IQGAP3 RYR1

1.23e-051105701135748872
Pubmed

Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.

ATP2B1 ATP2B2

2.39e-05470212209837
Pubmed

Expression and role of calcium-ATPase pump and sodium-calcium exchanger in differentiated trophoblasts from human term placenta.

ATP2B1 ATP2B2

2.39e-05470212784250
Pubmed

Calcium pumps of plasma membrane and cell interior.

ATP2B1 ATP2B2

2.39e-05470215101689
Pubmed

The plasma membrane calcium pump in health and disease.

ATP2B1 ATP2B2

2.39e-05470223413890
Pubmed

PSD95beta regulates plasma membrane Ca2+ pump localization at the photoreceptor synapse.

ATP2B1 ATP2B2

2.39e-05470219233278
Pubmed

Strain distribution pattern in AXB and BXA recombinant inbred strains for loci on murine chromosomes 10, 13, 17, and 18.

ARSB CSF1R

2.39e-0547028094988
Pubmed

Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.

ATP2B1 ATP2B2

2.39e-0547028245032
Pubmed

Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function.

ATP2B1 ATP2B2

2.39e-05470210577388
Pubmed

Structural organization, ion transport, and energy transduction of P-type ATPases.

ATP2B1 ATP2B2

2.39e-0547028634322
Pubmed

Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.

ATP2B1 ATP2B2

2.39e-0547027989379
Pubmed

Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps.

ATP2B1 ATP2B2

2.39e-05470211152753
Pubmed

Different conformational switches underlie the calmodulin-dependent modulation of calcium pumps and channels.

ATP2B1 RYR1

2.39e-05470218201104
Pubmed

PMCA1 depletion in mouse eggs amplifies calcium signaling and impacts offspring growth†.

ATP2B1 ATP2B2

2.39e-05470236130203
Pubmed

Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse.

ATP2B1 ATP2B2

2.39e-05470210434059
Pubmed

Association analysis between schizophrenia and the AP-3 complex genes.

AP3M2 AP3M1

3.98e-05570219481122
Pubmed

Differential regulation of the apical plasma membrane Ca(2+) -ATPase by protein kinase A in parotid acinar cells.

ATP2B1 ATP2B2

3.98e-05570217938178
Pubmed

Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants.

ATP2B1 ATP2B2

5.96e-05670212763866
Pubmed

Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression.

ARSB APOB

5.96e-0567021352323
Pubmed

IFN-γ mediates Paneth cell death via suppression of mTOR.

IFNGR2 MTOR

5.96e-05670234633285
Pubmed

Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange.

ATP2B1 ATP2B2

5.96e-05670212767889
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

ATP2B1 ATP2B2 RYR1

6.26e-053870330786075
Pubmed

Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship.

ARSB ARSI

8.33e-05770216174644
Pubmed

Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.

FAT4 FAT2

8.33e-05770216059920
Pubmed

Characterization of the adaptor-related protein complex, AP-3.

AP3M2 AP3M1

8.33e-0577029151686
Pubmed

Gene knockout studies of Ca2+-transporting ATPases.

ATP2B1 ATP2B2

1.11e-04870210951186
Pubmed

Association of the AP-3 adaptor complex with clathrin.

AP3M2 AP3M1

1.11e-0487029545220
Pubmed

Familial Hypercholesterolemia

APOB PPP1R17

1.11e-04870224404629
Pubmed

Integral and associated lysosomal membrane proteins.

MTOR RMC1 AP3M1 GAA

1.25e-0412670417897319
Pubmed

DNA methylation in tumor and matched normal tissues from non-small cell lung cancer patients.

MGMT KCNH5

1.78e-041070218349282
Pubmed

mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and PAPPA-KO mice.

MGMT MTOR

1.78e-041070227618784
Pubmed

HIV-1 Vpu inhibits accumulation of the envelope glycoprotein within clathrin-coated, Gag-containing endosomes.

AP3M2 AP3M1

1.78e-041070218076669
Pubmed

NEDL2 is an essential regulator of enteric neural development and GDNF/Ret signaling.

HECW1 MTOR

2.17e-041170225555806
Pubmed

Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.

HECTD4 ATP2B1

2.17e-041170222751097
Pubmed

A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits.

HECTD4 ATP2B1

2.60e-041270219396169
Pubmed

RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes.

POLA2 RPA3

2.60e-041270211473323
Pubmed

Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain.

FAT4 GAA

2.60e-041270223342162
Pubmed

Expression patterns of sulfatase genes in the developing mouse embryo.

ARSB ARSI

3.07e-041370220503373
Pubmed

NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner.

HECW1 MTOR

3.58e-041470227119228
Pubmed

Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.

ATP2B2 KCNH5

3.58e-041470219850283
Pubmed

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

MST1R NLRP1 POLA2 IQGAP3 KCNH5

4.29e-0431370520800603
Pubmed

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.

HECTD4 ATP2B1

4.71e-041670221572416
Pubmed

Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles.

AP3M2 AP3M1

4.71e-041670223247405
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

MTOR ARFGEF1 IPO13 IQGAP3

5.19e-0418370423956138
Pubmed

Mapping genetic loci that regulate lipid levels in a NZB/B1NJxRF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains.

APOB CPN1

5.33e-041770217496333
Pubmed

The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse.

AP3M2 AP3M1

5.98e-041870221998198
Pubmed

Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development.

FAT4 FAT2

5.98e-041870233108146
Pubmed

An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.

ABR ATP2B1 ATP2B2

6.62e-048470315123239
Pubmed

Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk.

MGMT POLA2 RPA3

6.62e-048470319237606
Pubmed

OTUB2 stabilizes U2AF2 to promote the Warburg effect and tumorigenesis via the AKT/mTOR signaling pathway in non-small cell lung cancer.

RTCB MTOR

8.18e-042170230662561
Pubmed

Myocardial Mycn is essential for mouse ventricular wall morphogenesis.

BMP10 MTOR

8.18e-042170223063798
Pubmed

Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

HECTD4 ATP2B1

8.18e-042170225249183
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

AP3M1 IQGAP3 RYR1 TDRD12

8.37e-0420870433230847
Pubmed

Transcriptome analysis of human gastric cancer.

FAM193A CSF1R ABR GSAP DEGS2 IL1RAP DMXL1

9.22e-0477270716341674
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

MTOR ARFGEF1 RPS10P5 DIS3

9.46e-0421570435973513
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

TRIM46 UBR1 HECTD4

9.47e-049570329643511
Pubmed

Genetic variation in healthy oldest-old.

MTOR APOB

1.07e-032470219680556
Pubmed

Human immunodeficiency virus type-1 gag and host vesicular trafficking pathways.

AP3M2 AP3M1

1.07e-032470220012524
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

NLRP1 DNMBP DIS3

1.16e-0310270310231032
Pubmed

Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent mechanism.

AP3M2 AP3M1

1.16e-032570211110696
Pubmed

Analysis of multiple candidate genes in association with phenotypes of multiple sclerosis.

IFNGR2 HELZ

1.26e-032670220378664
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

RTCB MTOR IPO13 HELZ RPA3 ATP2B2 DIS3 IQGAP3 CLASRP

1.30e-03132170927173435
Pubmed

Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.

MST1R CSF1R

1.46e-032870218593464
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

MGMT PBLD CPN1 DNMBP AP3M1

1.51e-0341570516385451
Pubmed

Biology, structure and mechanism of P-type ATPases.

ATP2B1 ATP2B2

1.57e-032970215071553
Pubmed

Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway.

ARFGEF1 AP3M1

1.67e-033070227568566
Pubmed

Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice.

MTOR POLA2

1.67e-033070228077597
Pubmed

UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target.

MTOR DIS3

1.67e-033070232867711
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

FAT4 NEB AP3M1 ATP2B1 RYR1 FHIP2B

1.81e-0363870631182584
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

FAT2 CSF1R APOB GAA

1.82e-0325770416335952
Pubmed

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia.

POC1B ATP2B1

1.90e-033270224954895
GeneFamilyATPases Ca2+ transporting

ATP2B1 ATP2B2

2.46e-0494821209
GeneFamilyCadherin related

FAT4 FAT2

9.15e-041748224
GeneFamilySulfatases

ARSB ARSI

1.03e-0318482410
GeneFamilyCarboxypeptidases

CPXM1 CPN1

1.40e-03214821321
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ABR HECW1

4.10e-0336482823
GeneFamilyReceptor Tyrosine Kinases|CD molecules

MST1R CSF1R

5.05e-0340482321
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 CPXM1 PLEKHH2 ARSI CDH11 SVEP1

7.19e-0719970621335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 PBLD RYR1 KCNH5 TDRD12

6.61e-061677053edb0570e583bb527165bcd8a4c25a042054043b
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

MST1R MTOR ARSI IQGAP3 CDH11

8.07e-06174705fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

PAPLN PLEKHH2 ARSI CDH11 SVEP1

8.76e-06177705cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

PAPLN PLEKHH2 ARSI CDH11 SVEP1

8.76e-06177705db222faaecbe5600da39277243c4e7e764eb63c9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 FAT4 HECW1 APOB NEB

1.06e-051847052cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 FAT4 HECW1 APOB NEB

1.06e-05184705ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 FAT4 HECW1 APOB NEB

1.06e-051847052b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FAT2 CPN1 PPP1R17 RYR1

1.14e-0588704b4620e79ea80681305434707e87cb02a7c6a5e4f
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FAT2 CPN1 PPP1R17 RYR1

1.14e-05887047992f8e621edf464bffcb70a6cc5f3b60c1d96f8
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FAT2 CPN1 PPP1R17 RYR1

1.14e-0588704b7b55f51af8ffa82813a4747580985a430da9ed1
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

FAT4 HECW1 PLEKHH2 CDH11 SVEP1

1.14e-05187705bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARSB CSF1R IL1RAP DNMBP RYR1

1.23e-051907052d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell21-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

FAT4 PLEKHH2 ARSI CDH11 SVEP1

1.36e-051947058fc98d2c9d94f3bc6292265e20ab71c4f1f37bb3
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 HECW1 PLEKHH2 CDH11 SVEP1

1.43e-05196705e7bfd4fb400ae0c473131d0fa306c26be08a6d03
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 HECW1 PLEKHH2 CDH11 SVEP1

1.43e-0519670582fad623212d986a7fca3496faf3f8c8f5b83a11
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 HECW1 PLEKHH2 CDH11 SVEP1

1.43e-0519670585e5046f774537684e1443c0fc147d562b7068d0
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 HECW1 PLEKHH2 CDH11 SVEP1

1.51e-05198705300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CPXM1 PLEKHH2 ARSI CDH11 SVEP1

1.58e-052007059b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellwk_20-22-Mesenchymal-Fibroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CPXM1 PLEKHH2 ARSI CDH11 SVEP1

1.58e-0520070594bd00fb6ff0dcb668eb36ec2085f1c3128855b6
ToppCellwk_15-18-Mesenchymal-Fibroblast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CPXM1 PLEKHH2 ARSI CDH11 SVEP1

1.58e-052007054f624c3c57d1a84baa86d0830cb1b83ae110bf67
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

PLEKHH2 ATP2B1 ARSI CDH11 SVEP1

1.58e-05200705bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAM29 ATP2B2 RYR1 KCNH5

9.17e-051507040205318a870e091add66ee4305747dda9f51510d
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

PLEKHH2 ARSI CDH11 SVEP1

1.15e-041597043f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

MST1R FER1L4 DNMBP IQGAP3

1.15e-04159704655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Etv1_(Deep_layer_pyramidal_cells-Etv1_typically_marks_layer_5b,_but_some_expression_in_layer_6,_especially_in_medial_regions_like_cingulate)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PAPLN B4GALNT3 TDRD12

1.16e-0460703f20230c11a2ca2f66650e53ea6eaa301402294c0
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Etv1_(Deep_layer_pyramidal_cells-Etv1_typically_marks_layer_5b,_but_some_expression_in_layer_6,_especially_in_medial_regions_like_cingulate)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PAPLN B4GALNT3 TDRD12

1.16e-046070371e2aa3da41319c72b4eac30e54c65e65e62a3d9
ToppCelldroplet-Fat-SCAT-30m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP10 HECTD4 PAPLN NEB

1.18e-0416070467ee7a314d7d4d3ea206e0158083f36f6dd7e80b
ToppCelldroplet-Fat-SCAT-30m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP10 HECTD4 PAPLN NEB

1.18e-04160704759749f708c3a2b36692d42499f19aff937e592f
ToppCelldroplet-Fat-SCAT-30m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP10 HECTD4 PAPLN NEB

1.18e-04160704fc76337ad766c859db390ef8b6fb9caeaace3a56
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PAPLN NEB RPA3 IQGAP3

1.21e-041617042165897924c790fec43502283f1df221c56c1e9f
ToppCellAdult-Mesenchymal-myofibroblast_cell-D231|Adult / Lineage, Cell type, age group and donor

FAT4 PAPLN PLEKHH2 CDH11

1.29e-041647043d8ff70fe5582d1fb56b338be8b76fa1428b3657
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

PLEKHH2 ARSI CDH11 SVEP1

1.29e-041647042ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEB ARSI CDH11 SVEP1

1.45e-0416970416c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT4 PLEKHH2 CDH11 SVEP1

1.45e-04169704c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

ABR PAPLN PLEKHH2 SVEP1

1.45e-0416970484b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN2(Gad1Gad2)-Sema3e-Inhibitory_Neuron.Gad1Gad2.Sema3e-Kcng4_(GABAergic,_K_Channel_State,_Sema3e+_SN/VTA_(SNr))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FER1L4 APOB IQGAP3

1.54e-0466703d5e878ffc0b942a35391c7dd73b30cec59f21b39
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN2(Gad1Gad2)-Sema3e-Inhibitory_Neuron.Gad1Gad2.Sema3e-Kcng4_(GABAergic,_K_Channel_State,_Sema3e+_SN/VTA_(SNr))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FER1L4 APOB IQGAP3

1.54e-0466703fdb695bbda639112c2f7b714adb7501aef4be19e
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN2(Gad1Gad2)-Sema3e|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FER1L4 APOB IQGAP3

1.54e-0466703de909119de42711b6580274b1200c0e1c6ad2f55
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 B3GLCT CSF1R CTC1

1.55e-041727041f335ccb92b22d0412954e8fc3af212f96410b67
ToppCelldroplet-Liver-nan-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 B3GLCT CSF1R CTC1

1.55e-04172704bb96c896d125e10b71e94e2bdad243899045af5c
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

B3GLCT ZBED4 NEB DNMBP

1.59e-0417370442c911ed16fabdabef063830e8407192d8bde950
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HECW1 PLEKHH2 IL1RAP KCNH5

1.59e-041737048335b77f730ed43fc348a005566e73a103c6774b
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Enterocyte|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFNGR2 APOB CPN1 ATP2B1

1.62e-041747042fbdb62e269acf4447b171700a615e878dde7f9f
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFNGR2 APOB CPN1 ATP2B1

1.62e-041747047c52b5d8f1e65e5208c952be341fa155ed0e6e76
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 PAPLN PLEKHH2 CDH11

1.66e-041757041799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GLCT B4GALNT3 CDH11 KCNH5

1.66e-0417570490e29945aa861082c94bb4f331161adc3a6ef899
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GLCT B4GALNT3 CDH11 KCNH5

1.70e-04176704e4b21fd6a5e0c5950f27c3e1868318e48330ae5e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GLCT B4GALNT3 CDH11 KCNH5

1.73e-04177704bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GLCT B4GALNT3 CDH11 KCNH5

1.77e-04178704431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GLCT B4GALNT3 CDH11 KCNH5

1.81e-041797047954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GLCT B4GALNT3 CDH11 KCNH5

1.81e-04179704f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Phlda1-Inhibitory_Gad1Gad2_Htr3a.Phlda1_(Interneuron,__(candidate_CGE-derived_3))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

PAPLN PPP1R17 ARSI

1.83e-04707030f1dba07a2cd974a25239ae1728cfb007a37954c
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Phlda1|Hippocampus / BrainAtlas - Mouse McCarroll V32

PAPLN PPP1R17 ARSI

1.83e-0470703c579fd093d30a5ee56f7cf1039120d00a6369649
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Phlda1-Inhibitory_Gad1Gad2_Htr3a.Phlda1_(Interneuron,__(candidate_CGE-derived_3))|Hippocampus / BrainAtlas - Mouse McCarroll V32

PAPLN PPP1R17 ARSI

1.83e-0470703511ca39208a8a0efd24cca47270083d5024e6972
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CPXM1 PAPLN ARSI CDH11

1.85e-04180704935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell5'-Airway_Nasal-Mesenchymal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CPXM1 PAPLN ARSI CDH11

1.85e-041807043dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GLCT B4GALNT3 CDH11 KCNH5

1.85e-04180704b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLEKHH2 IL1RAP ATP2B2 KCNH5

1.85e-041807045391d23817f5cc88a0871ddb98968897c839f464
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GLCT PLEKHH2 IL1RAP KCNH5

1.85e-04180704a407376209d80177bf7fc4200219030c83cb5f14
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPXM1 ARSI CDH11 SVEP1

1.89e-04181704269b39ac65790061d54eab47a8eeb024403f0348
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPXM1 ARSI CDH11 SVEP1

1.89e-04181704cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPXM1 ARSI CDH11 SVEP1

1.89e-04181704c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 PAPLN APOB PLEKHH2

1.89e-04181704b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellLPS_only-Myeloid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IFNGR2 CSF1R GSAP IL1RAP

1.93e-04182704666ac86ee5f6fa9241ae8d80340743707e54b278
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GLCT B4GALNT3 CDH11 KCNH5

1.97e-0418370465f2a5895d166189a095cf7ea9dda171f0419b08
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HECW1 PLEKHH2 IL1RAP KCNH5

2.01e-041847046475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPN1 DEGS2 PLEKHH2 GAA

2.05e-041857046da9a06e1514d5d5f47359a14637f02539846096
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPN1 DEGS2 PLEKHH2 GAA

2.05e-041857044a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GLCT PLEKHH2 IL1RAP KCNH5

2.05e-041857045a0340c25196453f19e424d346efbf66d2c53ac3
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 PLEKHH2 IL1RAP KCNH5

2.05e-0418570410da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PAPLN PLEKHH2 CDH11 SVEP1

2.10e-041867045473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellLPS-antiTNF-Myeloid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IFNGR2 CSF1R GSAP IL1RAP

2.10e-04186704839c6da5244f469461b2e5563e36162b2911cd01
ToppCell(2)_Fibroblasts-(20)_Fibro-1|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

CPXM1 ARSI CDH11 SVEP1

2.10e-04186704e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCellMonocytes-M2-like_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

PER3 GSAP NEB TDRD12

2.14e-0418770459e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARSB HECW1 PAPLN PBLD

2.18e-04188704f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARSB HECW1 PAPLN PBLD

2.18e-041887040792432cd4c564dea1102241ea9884f7ced7658c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARSB HECW1 PAPLN PBLD

2.23e-04189704204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHH2 ARSI CDH11 SVEP1

2.23e-04189704a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHH2 ARSI CDH11 SVEP1

2.23e-04189704e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IFNGR2 ARSB CSF1R MTOR

2.23e-04189704a2f4f1dd5452f7efb7427919a0b90875cf2e1dc7
ToppCellMacrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ARSB CSF1R ERAP2 GAA

2.23e-04189704c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARSB HECW1 PAPLN PBLD

2.23e-0418970413fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IFNGR2 ARSB CSF1R MTOR

2.23e-0418970454a45b0cb7dea01caf1cf0a2664c40e5779a0b61
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHH2 ARSI CDH11 SVEP1

2.23e-041897042a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAPLN PLEKHH2 CDH11 SVEP1

2.27e-0419070445df8fee00f8949937863159d7aa042e72748d9b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHH2 ARSI CDH11 SVEP1

2.27e-04190704841cd55861b43578d704418b9bc0af2e8b88323a
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHH2 ARSI CDH11 SVEP1

2.27e-04190704d60395739458d7f47a3350ade751fe3819500320
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHH2 ARSI CDH11 SVEP1

2.32e-04191704b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT4 PLEKHH2 CDH11 SVEP1

2.32e-041917046688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHH2 ARSI CDH11 SVEP1

2.36e-041927046f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT4 CPXM1 CDH11 SVEP1

2.36e-04192704f053b89bfd6048c227667ff01c38df7c51d8a496
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MST1R CPXM1 CDH11 SVEP1

2.36e-041927048937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHH2 ARSI CDH11 SVEP1

2.36e-04192704f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MST1R CPXM1 CDH11 SVEP1

2.36e-04192704e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHH2 ARSI CDH11 SVEP1

2.36e-04192704dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MST1R CPXM1 CDH11 SVEP1

2.36e-04192704ac1477433704573f95111eee6263b93668d2845e
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHH2 ARSI CDH11 SVEP1

2.36e-041927043d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHH2 ARSI CDH11 SVEP1

2.36e-04192704ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHH2 ARSI CDH11 SVEP1

2.36e-04192704deeecd26972241846b4cb998edf0c7a87ff0c4df
Druggramicidin s

IARS2 PBLD ATP2B1 ATP2B2

4.46e-0637684CID000073357
DrugFS86

STK36 NLRP1

8.79e-062682CID003043275
Diseaseaspartate aminotransferase measurement

TRIM46 CSF1R ATXN1 ERAP2 MTOR HECTD4 CPN1 PPP1R17 DNMBP KIAA2012

4.03e-059046810EFO_0004736
DiseaseHailey-Hailey disease (implicated_via_orthology)

ATP2B1 ATP2B2

7.80e-056682DOID:0050429 (implicated_via_orthology)
DiseaseMULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE

NEB RYR1

7.80e-056682C1854678
Diseasecrescentic glomerulonephritis (implicated_via_orthology)

CSF1R MTOR

7.80e-056682DOID:13139 (implicated_via_orthology)
Diseasecalpastatin measurement

CPN1 DNMBP

1.45e-048682EFO_0008065
DiseaseCMRF35-like molecule 6 measurement

POC1B ATP2B1

1.45e-048682EFO_0008086
DiseaseFamilial hypercholesterolemia

APOB PPP1R17

1.45e-048682cv:C0020445
Diseasefamilial hypercholesterolemia (is_implicated_in)

APOB PPP1R17

2.33e-0410682DOID:13810 (is_implicated_in)
Diseaseadseverin measurement

CPN1 DNMBP

2.33e-0410682EFO_0801358
Disease3-hydroxyanthranilate 3,4-dioxygenase measurement

CPN1 DNMBP

2.84e-0411682EFO_0021862
DiseaseCongenital myopathy (disorder)

NEB RYR1

3.40e-0412682C0270960
Diseasecreatine kinase measurement

CPN1 NEB IQGAP3

3.47e-0459683EFO_0004534
Diseasebeta-amyloid 1-42 measurement, cerebrospinal fluid biomarker measurement

FAT4 HECW1

4.68e-0414682EFO_0004670, EFO_0006794
Diseasenasopharynx carcinoma (is_implicated_in)

MST1R CSF1R

5.39e-0415682DOID:9261 (is_implicated_in)
Diseasegranulysin measurement

ERAP2 CPN1

5.39e-0415682EFO_0008144
DiseaseHyperlipoproteinemia Type IIa

APOB PPP1R17

6.15e-0416682C0745103
Diseaseneutrophil collagenase measurement

CPN1 DNMBP

6.15e-0416682EFO_0008248
Diseasecaudal anterior cingulate cortex volume measurement

FAT2 HECW1

6.96e-0417682EFO_0010289
Diseasemyocardial infarction

HECTD4 APOB DNMBP ATP2B1 GAA

1.29e-03350685EFO_0000612
DiseaseSquamous cell carcinoma of esophagus

FAT4 FAT2 MGMT

1.39e-0395683C0279626
DiseaseCalcium channel blocker use measurement

TRIM46 B3GLCT ATP2B1 SVEP1

1.50e-03213684EFO_0009930
DiseaseLeft Ventricular Hypertrophy

MTOR GAA

1.52e-0325682C0149721
Diseasemean arterial pressure, alcohol drinking

POC1B HECTD4 ATP2B1

1.52e-0398683EFO_0004329, EFO_0006340
Diseaselevel of Sterol ester (27:1/18:2) in blood serum

APOB CLASRP

1.64e-0326682OBA_2045194
Diseaselevel of Sterol ester (27:1/16:0) in blood serum

APOB CLASRP

1.64e-0326682OBA_2045191

Protein segments in the cluster

PeptideGeneStartEntry
HTPVDHPDYPLLQDA

ABR

256

Q12979
QDEHPQYHSPPDVVI

ADAM29

21

Q9UKF5
THSPLFHQARPVDYP

B3GLCT

436

Q6Y288
EFPPHLDVYIEDPHL

CTC1

941

Q2NKJ3
RNIPAVDPHLQFYHP

B4GALNT3

71

Q6L9W6
PPHIIFILTDDQGYH

ARSI

46

Q5FYB1
VSHHEPESPQLRYLP

ARFGEF1

236

Q9Y6D6
DNPPRFQHHPYVTHI

FAT4

2461

Q6V0I7
IVPNHHLPLPTYYTL

CPXM1

456

Q96SM3
SHPHSEQYPDLLPLE

DNMBP

436

Q6XZF7
DVENVPPVISTPHHY

AP3M1

41

Q9Y2T2
SVPHPYESRHVVVHP

ATXN1

351

P54253
HVLSPTLPQYHPLQL

DMXL1

1316

Q9Y485
HIHQLPLQVDPAPDY

FAM193A

236

P78312
NAPLHAPPSEHYTIV

ATP2B1

961

P20020
PLHSPPSEHYTIIFN

ATP2B2

986

Q01814
LDLPLYPAHPQDFHE

PBLD

121

P30039
EAENVPPVIPTPHHY

AP3M2

41

P53677
VPPVIHSPNDHVVYE

IL1RAP

241

Q9NPH3
SLRPEHHHYPTIDEP

HECW1

816

Q76N89
IEEFPVPALHHPVFQ

MGMT

76

P16455
QLVPEHVETRPLYHP

FER1L4

1441

A9Z1Z3
EHSPIQADAKHPFYP

KCNH5

886

Q8NCM2
SPFRIIPYLIHVHHP

PER3

226

P56645
IPYLIHVHHPAQPEL

PER3

231

P56645
HPPRFTQLHYEASVP

FAT2

1551

Q9NYQ8
PHPHIHEYLLDPYIS

FHIP2B

636

Q86V87
VHPEEVTFHLYLIPS

NLRP1

1241

Q9C000
PTELFILPVEIHYHT

KIAA2012

416

Q0VF49
RLHFDSPPHLLDIYP

POC1B

316

Q8TC44
IFLIHFDPNLHTPIY

OR13H1

46

Q8NG92
TPARLHPHEVYLDPA

HECTD4

3481

Q9Y4D8
HINLPLPAPHAQYAI

HELZ

1341

P42694
AQDDYRILVHAPHPP

IQGAP3

836

Q86VI3
LRNPYHHSLPFSIPV

PLEKHH2

1111

Q8IVE3
VQFLYPHIESHPLPE

GSAP

151

A4D1B5
FQVPDLHIPEFQLPH

APOB

2731

P04114
HTHPPDEFLFTPVVV

CSF1R

506

P07333
YPLLFNVSIPHHEEV

BMP10

126

O95393
YVLEFSDHPGIHEPL

CPN1

61

P15169
PPEFLHETYHANVPE

CDH11

156

P55287
EHHDFPSIPGYNLPL

DEGS2

261

Q6QHC5
YEVPLETPHVHSRAP

GAA

191

P10253
FHTPPSIPLQIEEYL

IFNGR2

281

P38484
HKHSVPVYFPAQDPR

ARSB

506

P15848
SVVIPLHYDLFVHPN

ERAP2

71

Q6P179
HPLLIPYDEDFNHEP

C19orf54

211

Q5BKX5
LPQFEPVPLEHPHYE

RYR1

1241

P21817
PVPLEHPHYEVSRVD

RYR1

1246

P21817
VHIFAHEPAHFPPIE

IPO13

751

O94829
HEPAHFPPIEALFLL

IPO13

756

O94829
DHPLPTVHPQVTYAY

MTOR

1686

P42345
FPPHHPLIAVDYQLT

RTCB

381

Q9Y3I0
EYSEDVHLHTPPAPV

TRIM46

516

Q7Z4K8
HDPLHQEVSFGVPYP

RNF38

346

Q9H0F5
PEHFHTLPPQAVEFI

TDRD12

986

Q587J7
SPQHYPPREIVAHII

SIMC1

496

Q8NDZ2
PILPHLAEEVFQHIP

IARS2

836

Q9NSE4
LRDVHHEPVYPQPPF

POLA2

426

Q14181
VSVHVHPAFTPPYLF

SVEP1

601

Q4LDE5
IHDFPQFYPLGIVQH

RPA3

106

P35244
PQPHYLLPDTNVLLH

DIS3

61

Q9Y2L1
PDLLYHPFIAGHVTI

STK36

246

Q9NRP7
PEPFHDDIPTESIHY

C1orf105

126

O95561
DVRAHLDHIPDYTPP

CLASRP

81

Q8N2M8
LHIPPFIPGVFSEHL

PPP1R17

71

O96001
DYLHLPPEIVPATLH

RPS10P5

81

Q9NQ39
EPNPGVHYEYHLPLR

PAPLN

286

O95428
TFHHPVLPARSIQPY

RMC1

301

Q96DM3
FHYLLGVTPPEELHT

UBR1

1516

Q8IWV7
IQPGIYHPDIQLLHP

VPS13C

1306

Q709C8
PPYRHIDPFDLTHFL

MST1R

1286

Q04912
PHLPALHYDEPAENL

ZBED4

256

O75132
YILPPDAVPFVHAHH

NEB

4226

P20929