Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR52L2P OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 OR52Z1P OR51V1 OR2T11 OR14A16 OR4D2 OR52J3	7.86e-25	431	83	27	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	FZD7 OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR52L2P TAS2R36 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 ADGRF4 TAS2R30 OR52Z1P OR51V1 OR2T11 OR14A16 CRHR2 CX3CR1 OR4D2 OR52J3	2.12e-23	884	83	33	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	MPL FZD7 OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR52L2P TAS2R36 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 GRIA1 OR4D6 OR1K1 OR4C13 OR4C12 ADGRF4 TAS2R30 OR52Z1P OR51V1 OR2T11 OR14A16 CRHR2 CX3CR1 OR4D2 OR52J3	1.02e-19	1353	83	35	GO:0004888
GeneOntologyMolecularFunction	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity	ALG10 ALG10B	1.71e-05	2	83	2	GO:0106073
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR52L2P TAS2R36 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 TAS2R30 OR52Z1P OR51V1 OR2T11 OR14A16 OR4D2 OR52J3	1.53e-26	485	83	29	GO:0050907
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR51A7 OR6V1 OR4P4 OR4S1 CALCA OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR52L2P TAS2R36 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 TAS2R30 OR52Z1P OR51V1 OR2T11 OR14A16 OR4D2 OR52J3	1.35e-25	582	83	30	GO:0050906
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR52L2P TAS2R36 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 TAS2R30 OR52Z1P OR51V1 OR2T11 OR14A16 OR4D2 OR52J3	1.39e-25	524	83	29	GO:0009593
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR52L2P OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 OR52Z1P OR51V1 OR2T11 OR14A16 OR4D2 OR52J3	3.61e-25	432	83	27	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR52L2P TAS2R36 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 TAS2R30 OR52Z1P OR51V1 OR2T11 OR14A16 OR4D2 OR52J3	4.71e-25	547	83	29	GO:0007606
GeneOntologyBiologicalProcess	sensory perception of smell	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR52L2P OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 OR52Z1P OR51V1 OR2T11 OR14A16 OR4D2 OR52J3	2.56e-24	465	83	27	GO:0007608
GeneOntologyBiologicalProcess	detection of stimulus	OR51A7 OR6V1 OR4P4 OR4S1 CALCA OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR52L2P TAS2R36 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 TAS2R30 OR52Z1P OR51V1 OR2T11 OR14A16 OR4D2 OR52J3	7.05e-23	722	83	30	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	OR51A7 OR6V1 OR4P4 OR4S1 CALCA OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR52L2P TAS2R36 OR51M1 OR4D9 OR52H1 ALG10 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 ALOXE3 OR4C12 TAS2R30 OR52Z1P OR51V1 OR2T11 OR14A16 ALG10B OR4D2 OR52J3	3.16e-21	1072	83	33	GO:0007600
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	MPL FZD7 OR51A7 OR6V1 OR4P4 OR4S1 CALCA OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR52L2P TAS2R36 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 ADGRF4 TAS2R30 OR52Z1P OR51V1 OR2T11 OR14A16 CRHR2 CX3CR1 OR4D2 OR52J3	9.68e-20	1395	83	35	GO:0007186
GeneOntologyBiologicalProcess	dolichol-linked oligosaccharide biosynthetic process	SRD5A3 ALG10 ALG10B	9.16e-05	22	83	3	GO:0006488
GeneOntologyBiologicalProcess	dolichol metabolic process	SRD5A3 ALG10 ALG10B	1.20e-04	24	83	3	GO:0019348
GeneOntologyBiologicalProcess	polyprenol metabolic process	SRD5A3 ALG10 ALG10B	2.13e-04	29	83	3	GO:0016093
GeneOntologyCellularComponent	axonal spine	GRIA1 SLC9A6	9.30e-05	4	83	2	GO:0044308
GeneOntologyCellularComponent	host cell part	GBP4 GBP7	2.31e-04	6	83	2	GO:0033643
GeneOntologyCellularComponent	host intracellular part	GBP4 GBP7	2.31e-04	6	83	2	GO:0033646
GeneOntologyCellularComponent	host cell cytoplasm part	GBP4 GBP7	2.31e-04	6	83	2	GO:0033655
GeneOntologyCellularComponent	symbiont-containing vacuole	GBP4 GBP7	2.31e-04	6	83	2	GO:0020003
GeneOntologyCellularComponent	symbiont-containing vacuole membrane	GBP4 GBP7	2.31e-04	6	83	2	GO:0020005
GeneOntologyCellularComponent	host intracellular region	GBP4 GBP7	2.31e-04	6	83	2	GO:0043656
GeneOntologyCellularComponent	host cell cytoplasm	GBP4 GBP7	2.31e-04	6	83	2	GO:0030430
GeneOntologyCellularComponent	recycling endosome membrane	FZD7 SLC9A9 GRIA1 SLC9A6	1.04e-03	112	83	4	GO:0055038
GeneOntologyCellularComponent	host cellular component	GBP4 GBP7	1.58e-03	15	83	2	GO:0018995
Domain	Olfact_rcpt	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 OR51V1 OR2T11 OR14A16 OR4D2 OR52J3	7.05e-23	393	80	25	IPR000725
Domain	GPCR_Rhodpsn_7TM	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 OR51V1 OR2T11 OR14A16 CX3CR1 OR4D2 OR52J3	2.05e-18	670	80	26	IPR017452
Domain	7tm_1	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 OR51V1 OR2T11 OR14A16 CX3CR1 OR4D2 OR52J3	2.64e-18	677	80	26	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 OR51V1 OR2T11 OR14A16 CX3CR1 OR4D2 OR52J3	3.52e-18	685	80	26	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 OR51V1 OR2T11 OR14A16 CX3CR1 OR4D2 OR52J3	4.36e-18	691	80	26	PS50262
Domain	GPCR_Rhodpsn	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 OR51V1 OR2T11 OR14A16 CX3CR1 OR4D2 OR52J3	4.52e-18	692	80	26	IPR000276
Domain	Alg10	ALG10 ALG10B	1.81e-05	2	80	2	IPR016900
Domain	DIE2_ALG10	ALG10 ALG10B	1.81e-05	2	80	2	PF04922
Domain	Na/H_exchanger_6	SLC9A9 SLC9A6	5.42e-05	3	80	2	IPR002090
Domain	NaH_exchanger	SLC9A9 SLC9A6	6.40e-04	9	80	2	IPR004709
Domain	GBP_C	GBP4 GBP7	7.97e-04	10	80	2	PF02841
Domain	G_GB1_RHD3_dom	GBP4 GBP7	9.72e-04	11	80	2	IPR030386
Domain	Guanylate-bd_C	GBP4 GBP7	9.72e-04	11	80	2	IPR003191
Domain	GBP	GBP4 GBP7	9.72e-04	11	80	2	PF02263
Domain	Cation/H_exchanger_CPA1	SLC9A9 SLC9A6	9.72e-04	11	80	2	IPR018422
Domain	Guanylate-bd_N	GBP4 GBP7	9.72e-04	11	80	2	IPR015894
Domain	G_GB1_RHD3	GBP4 GBP7	9.72e-04	11	80	2	PS51715
Domain	DUF4599	SPATA31D4 SPATA31D3	1.16e-03	12	80	2	PF15371
Domain	DUF4599	SPATA31D4 SPATA31D3	1.16e-03	12	80	2	IPR027970
Domain	Na_H_Exchanger	SLC9A9 SLC9A6	1.59e-03	14	80	2	PF00999
Domain	Cation/H_exchanger	SLC9A9 SLC9A6	1.59e-03	14	80	2	IPR006153
Domain	GPCR_2_secretin-like	FZD7 ADGRF4 CRHR2	2.17e-03	60	80	3	IPR000832
Domain	GPCR_2-like	FZD7 ADGRF4 CRHR2	2.17e-03	60	80	3	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	FZD7 ADGRF4 CRHR2	2.28e-03	61	80	3	PS50261
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 OR52Z1P OR51V1 OR2T11 OR14A16 OR4D2 OR52J3	1.78e-22	417	69	26	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 OR51V1 OR2T11 OR14A16 OR4D2 OR52J3	6.67e-22	389	69	25	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR51A7 OR6V1 OR4P4 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR1K1 OR4C13 OR4C12 TAS2R30 OR52Z1P OR51V1 OR2T11 OR14A16 OR4D2 OR52J3	5.08e-19	636	69	27	M41834
Pubmed	The human olfactory receptor gene family.	OR51A7 OR6V1 OR4S1 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR52L2P OR51M1 OR4D9 OR52H1 OR52L1 OR4D1 OR4D6 OR4C13 OR4C12 OR52Z1P OR51V1 OR2T11 OR14A16 OR4D2 OR52J3	4.75e-24	541	83	24	14983052
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR51A7 OR4P4 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR51M1 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR4C13 OR4C12 OR52Z1P OR51V1 OR4D2 OR52J3	1.70e-22	340	83	20	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR51A7 OR4P4 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR51M1 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR4C13 OR4C12 OR52Z1P OR51V1 OR4D2 OR52J3	1.70e-22	340	83	20	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR51A7 OR4P4 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR51M1 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR4C13 OR4C12 OR52Z1P OR51V1 OR4D2 OR52J3	2.02e-22	343	83	20	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR51A7 OR4P4 OR56B1 OR4S2 OR4C11 OR4A5 OR6K2 OR51I1 OR51M1 OR52H1 OR52L1 OR4D1 OR4C46 OR4D6 OR4C13 OR4C12 OR52Z1P OR51V1 OR4D2 OR52J3	2.41e-22	346	83	20	14611657
Pubmed	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.	OR51I1 OR51M1 OR52Z1P OR51V1	4.03e-08	15	83	4	11121057
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR4P4 OR4S2 OR4D1 OR4D6 OR1K1 OR4C13 OR4C12 OR4D2	5.72e-08	219	83	8	12213199
Pubmed	Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.	OR4D1 OR2T11 OR14A16 OR4D2	4.56e-06	46	83	4	32126975
Pubmed	Genes for endosomal pH regulators NHE6 and NHE9 are dysregulated in the substantia nigra in Parkinson's disease.	SLC9A9 SLC9A6	5.63e-06	2	83	2	38945311
Pubmed	The guanylate-binding proteins: emerging insights into the biochemical properties and functions of this family of large interferon-induced guanosine triphosphatase.	GBP4 GBP7	5.63e-06	2	83	2	21142871
Pubmed	Binding of the factor IX gamma-carboxyglutamic acid domain to the vitamin K-dependent gamma-glutamyl carboxylase active site induces an allosteric effect that may ensure processive carboxylation and regulate the release of carboxylated product.	F9 GGCX	5.63e-06	2	83	2	14660587
Pubmed	Genes for endosomal NHE6 and NHE9 are misregulated in autism brains.	SLC9A9 SLC9A6	5.63e-06	2	83	2	23508127
Pubmed	Posttranslational modifications of recombinant myotube-synthesized human factor IX.	F9 GGCX	5.63e-06	2	83	2	11133752
Pubmed	Vestibular hair bundles control pH with (Na+, K+)/H+ exchangers NHE6 and NHE9.	SLC9A9 SLC9A6	5.63e-06	2	83	2	17005858
Pubmed	Cloning, expression, and characterization of a novel guanylate-binding protein, GBP3 in murine erythroid progenitor cells.	GBP4 GBP7	5.63e-06	2	83	2	9659399
Pubmed	Gbp3 is associated with the progression of lupus nephritis by regulating cell proliferation, inflammation and pyroptosis.	GBP4 GBP7	5.63e-06	2	83	2	37621179
Pubmed	Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.	OR51I1 OR51M1 OR52Z1P	5.84e-06	15	83	3	10220430
Pubmed	A point mutation in the gene for asparagine-linked glycosylation 10B (Alg10b) causes nonsyndromic hearing impairment in mice (Mus musculus).	ALG10 ALG10B	1.69e-05	3	83	2	24303013
Pubmed	GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.	GBP4 GBP7	1.69e-05	3	83	2	35780181
Pubmed	Cell surface levels of organellar Na+/H+ exchanger isoform 6 are regulated by interaction with RACK1.	SLC9A9 SLC9A6	1.69e-05	3	83	2	18057008
Pubmed	GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.	GBP4 GBP7	1.69e-05	3	83	2	29128363
Pubmed	Functional genetic analysis of mouse chromosome 11.	ZNF423 ALG10 ALG10B	2.24e-05	23	83	3	12955145
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR56B1 OR4C11 OR4A5 OR52J3	3.05e-05	74	83	4	15081110
Pubmed	TRPV4 Channel Signaling in Macrophages Promotes Gastrointestinal Motility via Direct Effects on Smooth Muscle Cells.	PTGS1 CX3CR1	3.37e-05	4	83	2	29958798
Pubmed	The IKr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines.	ALG10 ALG10B	3.37e-05	4	83	2	14525949
Pubmed	Organellar Na+/H+ exchangers: novel players in organelle pH regulation and their emerging functions.	SLC9A9 SLC9A6	3.37e-05	4	83	2	21171650
Pubmed	Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice.	SLC16A1 CX3CR1	3.37e-05	4	83	2	37717033
Pubmed	ZER1 Contributes to the Carcinogenic Activity of High-Risk HPV E7 Proteins.	CUL2 UBR4	3.37e-05	4	83	2	36346242
Pubmed	Four Na+/H+ exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation.	SLC9A9 SLC9A6	5.60e-05	5	83	2	15522866
Pubmed	Microglial activation elicits a negative affective state through prostaglandin-mediated modulation of striatal neurons.	PTGS1 CX3CR1	8.39e-05	6	83	2	33476547
Pubmed	Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion.	CALCA CX3CR1	8.39e-05	6	83	2	36859544
Pubmed	VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo.	F9 GGCX	1.17e-04	7	83	2	29321368
Pubmed	Enhanced recruitment of endosomal Na+/H+ exchanger NHE6 into Dendritic spines of hippocampal pyramidal neurons during NMDA receptor-dependent long-term potentiation.	GRIA1 SLC9A6	1.17e-04	7	83	2	23303939
Pubmed	In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.	GBP4 GBP7	1.56e-04	8	83	2	16689661
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	NCAPD3 LRPPRC UBR4 CCAR1 ZFC3H1	1.58e-04	212	83	5	33853758
Pubmed	Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.	GBP4 GBP7	2.00e-04	9	83	2	24739961
Pubmed	Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria.	LRPPRC CX3CR1	2.50e-04	10	83	2	35384838
Pubmed	Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.	GBP4 GBP7	3.05e-04	11	83	2	24715728
Pubmed	Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.	GBP4 GBP7	3.05e-04	11	83	2	18025219
Pubmed	Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling.	GBP4 GBP7	3.66e-04	12	83	2	35906252
Pubmed	Szt2, a novel gene for seizure threshold in mice.	MPL KDM4A	4.31e-04	13	83	2	19624305
Pubmed	Mouse placenta fetal macrophages arise from endothelial cells outside the placenta.	SLC16A1 CX3CR1	4.31e-04	13	83	2	36473461
Pubmed	Disturbance of cerebellar synaptic maturation in mutant mice lacking BSRPs, a novel brain-specific receptor-like protein family.	GRIA1 SEZ6L	4.31e-04	13	83	2	16814779
Pubmed	Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse.	CALCA DYNC1I2	5.03e-04	14	83	2	21471385
Pubmed	Chromosomal localization of lipolytic enzymes in the mouse: pancreatic lipase, colipase, hormone-sensitive lipase, hepatic lipase, and carboxyl ester lipase.	MPL PTGS1	5.03e-04	14	83	2	8105016
Pubmed	Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development.	SLC9A9 SLC9A6	5.79e-04	15	83	2	24035762
Pubmed	Association of warfarin dose with genes involved in its action and metabolism.	F9 GGCX	6.61e-04	16	83	2	17048007
Pubmed	Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study.	NCAPD3 ALG10	6.61e-04	16	83	2	17903297
Pubmed	Global landscape of HIV-human protein complexes.	CUL2 NCAPD3 LRPPRC XPO5 UBR4 DYNC1I2	8.01e-04	457	83	6	22190034
Pubmed	Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef.	SLC9A9 SLC9A6	8.40e-04	18	83	2	24874739
Pubmed	A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection.	GBP4 GBP7	9.37e-04	19	83	2	21551061
Pubmed	Human chromosome 11 DNA sequence and analysis including novel gene identification.	OR4A5 OR4D9 OR52Z1P	9.43e-04	80	83	3	16554811
Pubmed	An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.	GBP4 GBP7	1.15e-03	21	83	2	19158679
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	NCAPD3 LRPPRC SLC16A1 ZFC3H1	1.42e-03	202	83	4	24639526
Pubmed	mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.	NALCN CCAR1 DYNC1I2	1.69e-03	98	83	3	34943047
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	EXOC6B NLRP1 SEZ6L	1.90e-03	102	83	3	10231032
Pubmed	Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development.	ALOXE3 DEGS1	1.90e-03	27	83	2	23096701
Pubmed	Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.	DEGS1 ELOVL7	1.90e-03	27	83	2	25269881
Cytoband	11p15.4	OR51A7 OR56B1 OR51I1 OR52L2P OR51M1 OR52H1 OR52L1 OR52Z1P OR51V1 OR52J3	3.20e-12	200	82	10	11p15.4
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	OR51A7 CALCA OR56B1 OR51I1 OR52L2P OR51M1 OR52H1 OR52L1 OR52Z1P OR51V1 OR52J3	5.57e-09	564	82	11	chr11p15
Cytoband	Ensembl 112 genes in cytogenetic band chr11q11	OR4P4 OR4S2 OR4C11 OR4A5 OR4C46	1.01e-08	40	82	5	chr11q11
Cytoband	11p11.12	OR4A5 OR4C46 OR4C13 OR4C12	1.00e-06	42	82	4	11p11.12
Cytoband	9q21.32	SPATA31D4 SPATA31D3	5.28e-04	19	82	2	9q21.32
Cytoband	1p22.2	GBP4 GBP7	1.16e-03	28	82	2	1p22.2
Cytoband	Xq26.2	USP26 FRMD7	1.16e-03	28	82	2	Xq26.2
Cytoband	Ensembl 112 genes in cytogenetic band chr11p11	OR4S1 OR4C13 OR4C12	2.65e-03	153	82	3	chr11p11
Cytoband	11q12.1	OR4P4 OR4D9 OR4D6	3.06e-03	161	82	3	11q12.1
Cytoband	11q11	OR4S2 OR4C11	3.23e-03	47	82	2	11q11
Cytoband	Ensembl 112 genes in cytogenetic band chrXq26	USP26 FRMD7 SLC9A6	3.62e-03	171	82	3	chrXq26
GeneFamily	Olfactory receptors, family 4	OR4P4 OR4S1 OR4S2 OR4C11 OR4A5 OR4D9 OR4D1 OR4C46 OR4D6 OR4C13 OR4C12 OR4D2	3.02e-14	129	65	12	151
GeneFamily	Olfactory receptors, family 52	OR52L2P OR52H1 OR52L1 OR52Z1P OR52J3	8.67e-07	49	65	5	165
GeneFamily	Alpha-1,2-glucosyltransferases	ALG10 ALG10B	1.27e-05	2	65	2	448
GeneFamily	Olfactory receptors, family 51	OR51A7 OR51I1 OR51M1 OR51V1	1.85e-05	44	65	4	164
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	OR4D6 MDGA2 OR4C13 OR4C12 OR51V1	3.49e-06	128	80	5	91072ca56bce2c552a95edd67e17f43d8cc1de95
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	OR4D6 MDGA2 OR4C13 OR4C12 OR51V1	5.23e-06	139	80	5	64c35411bbe67acb5010dadc4b0b1be0f8b17737
Drug	sodium oxalate	NLRP1 F9 GGCX	3.20e-06	9	78	3	CID000006125
Disease	Long Qt Syndrome 2	ALG10 ALG10B	1.57e-05	3	68	2	C3150943
Disease	phosphatidylcholine 38:5 measurement	LRPPRC RRN3 DYNC1I2	6.08e-05	33	68	3	EFO_0010387
Disease	nonsyndromic deafness (implicated_via_orthology)	ALG10 ALG10B	7.80e-05	6	68	2	DOID:0050563 (implicated_via_orthology)
Disease	Bronchial Hyperreactivity	CALCA PTGS1	3.40e-04	12	68	2	C0085129
Disease	ischemia (implicated_via_orthology)	CALCA CRHR2	6.96e-04	17	68	2	DOID:326 (implicated_via_orthology)
Disease	androstenedione measurement, estrone measurement	OR4D1 OR4D2	7.82e-04	18	68	2	EFO_0007970, EFO_0007972
Disease	S-warfarin to R-warfarin ratio measurement	ARFGEF3 SLC9A9 GRIA1	1.39e-03	95	68	3	EFO_0803331

Protein segments in the cluster

Peptide	Gene	Start	Entry
CTGYIFFYMHNEIFE	USP26	876	Q9BXU7
FQLGNYCNFYVMHRE	CCAR1	411	Q8IX12
NMCVAVTFFSHFFYL	ADGRF4	471	Q8IZF3
LSFMHAQSSFFQQGY	ACAP3	191	Q96P50
GLHNAMCKFTTAFFF	CX3CR1	96	P49238
NHKTSAFLGFCGFMF	ALG10B	171	Q5I7T1
ISFNGCLLQMYFFHS	OR6K2	91	Q8NGY2
GSCVSQMFFIHFIFV	OR52Z1P	81	P0C646
YFFAASVVANGVCHM	SLC16A1	331	P53985
TISYQGCMGQIFFFH	OR4D2	91	P58180
SFNGCMAQAYAEHIF	OR4C12	91	Q96R67
LMSTGLAHFTYTNFC	ALOXE3	476	Q9BYJ1
FQTSCKFSGNHMSIY	FRMD7	446	Q6ZUT3
FYYGFHSVCASNALM	HECTD2	636	Q5U5R9
EYVFHCQSAVMSATF	DYNC1I2	326	Q13409
LFNGCMTQVFGEHFF	OR4C46	91	A6NHA9
ACFAQEFFIHGFTVM	OR51A7	96	Q8NH64
FNACLVQMFFIHTFS	OR51I1	96	Q9H343
SHSIYFGACQIQMFC	OR51M1	101	Q9H341
FGACQIQMFCIHSFS	OR51M1	106	Q9H341
CIAQSYFIHGLSFME	OR51V1	106	Q9H2C8
SYNNCMIQLFTTHFF	OR4P4	91	Q8NGL7
SFNGCMTQLFSAHFF	OR4S1	91	Q8NGB4
SYVGCMLQLFGVHFF	OR4S2	91	Q8NH73
FIHLCFQEFFAAMSY	NLRP1	621	Q9C000
TKFTIYNNMFCAGFH	F9	386	P00740
CFAQIYAIHFFVGME	OR56B1	106	Q8NGI3
VTNFFWMFVEGCYLH	CRHR2	196	Q13324
CMIFQTYHQVEFGGF	KDM4A	671	O75164
VFGSFFLQHCVTMNT	LRPPRC	371	P42704
FLMQSDNFCSYIFTH	GBP4	276	Q96PP9
FQMQSENFCSYIFTH	GBP7	261	Q8N8V2
KMCNFHYQGFVDSIT	EXOC6B	66	Q9Y2D4
TYNECMTQVFALHLF	OR4C11	91	Q6IEV9
LFNGCMTQVFGEHFF	OR4C13	91	Q8NGP0
QGTNLMFAFFAQHFT	PTGS1	191	P23219
TISYNDCMAQIFFFH	OR4D6	91	Q8NGJ1
NEFYMSYHLFIVACA	GPM6B	216	Q13491
CFSFFYHMYGQHIGV	MDGA2	836	Q7Z553
HSISLAGCLTQMYFF	OR1K1	91	Q8NGR3
TISFSGCVTQMFFFH	OR4D9	91	Q8NGE8
TFTGCMVQFYFHFSL	OR6V1	91	Q8N148
SVFSNVMIHVVQYCF	SRD5A3	151	Q9H8P0
FLSGCYFMVAVAHVA	FZD7	291	O75084
HISQFFFMEDCKYQF	ELOVL7	221	A1L3X0
AMSFNIYFHALVCAV	ARFGEF3	1811	Q5TH69
SVQMFELFYSQHFSG	CUL2	536	Q13617
FGAYAFGSCINHSMT	DEGS1	71	O15121
MFFGQDQSFHELFCV	ELMO3	431	Q96BJ8
MQHIFAFFCTGFLGA	GRIA1	1	P42261
TISYQGCMAQIFFFH	OR4D1	91	Q15615
MNVPYCGSRSINHFF	OR2T11	161	Q8NH01
TFSLSYCGSNMVHQF	OR14A16	161	Q8NHC5
TFPGCLTQMFFLHYN	OR52H1	101	Q8NGJ2
YGACVAQMFLIHAFT	OR52J3	96	Q8NH60
SFQGCMGQLFIDHFF	OR4A5	91	Q8NH83
GYIVCLIQMFFIHAF	OR52L1	111	Q8NGH7
GYTVCLIQMFFTHAF	OR52L2P	111	Q8NGH6
MSFCSFFGGEVFQNH	MSRB1	1	Q9NZV6
CVFFRNNHFSTMTKY	MINDY2	441	Q8NBR6
SCHVQFFMFYLCSFK	RRN3	361	Q9NYV6
FMFCQAIIFSYPSTH	TAS2R30	261	P59541
FMFCQAIIFSYPSTH	TAS2R36	261	P0DTE0
TFQLHYQAFMLSCNF	SEZ6L	381	Q9BYH1
YMGLTLFTFQNHVFN	SLC9A6	396	Q92581
IFCYMGLALFTFQNH	SLC9A9	376	Q8IVB4
YAIHGYFCEVMFTAA	TMEM229B	16	Q8NBD8
VSFMFNGTSFGFVNC	INPPL1	546	O15357
VFVQHGRSSMFVFFN	SPATA31D4	516	Q6ZUB0
AIMTYVSCFYHAFAG	ACTN3	251	Q08043
CMLGTYTQDFNKFHT	CALCA	91	P01258
NHKTSAFLGFCGFMF	ALG10	171	Q5BKT4
MFFQHFIECIFHFNN	NCAPD3	1051	P42695
VFVQHGRSSMFVFFN	SPATA31D3	516	P0C874
RSIGLFFVSYFHCMN	GGCX	276	P38435
LFGVCVYSFMCQHSL	TMEM104	276	Q8NE00
MQRFFSTLYENCFHI	XPO5	836	Q9HAV4
IQRFFAYHMIETYGC	TMEM168	451	Q9H0V1
SQSMPHFGTRYVCQF	MPL	81	P40238
VMQFGNISAFHCNYC	ZNF423	471	Q2M1K9
SHVLQMLFFSYCQGK	UBR4	2116	Q5T4S7
NPQNAEVFYHMCKFF	ZFC3H1	1666	O60293
VTYNMFGHFKFCITL	SLC35E3	251	Q7Z769
GVQMFGTFTYHCVVN	NALCN	196	Q8IZF0