Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionHsp90 protein binding

GBP1 GBP2 EIF2AK3 GBP3 USP19

2.59e-0955215GO:0051879
GeneOntologyMolecularFunctionheat shock protein binding

BCOR GBP1 GBP2 EIF2AK3 GBP3 USP19

1.32e-08163216GO:0031072
GeneOntologyMolecularFunctionGDP phosphatase activity

GBP1 GBP2 GBP3

2.19e-0712213GO:0004382
GeneOntologyMolecularFunctionnucleoside diphosphate phosphatase activity

GBP1 GBP2 GBP3

1.13e-0620213GO:0017110
GeneOntologyMolecularFunctionspectrin binding

GBP1 GBP2 GBP3

5.87e-0634213GO:0030507
GeneOntologyMolecularFunctionlipopolysaccharide binding

GBP1 GBP2 GBP3

1.68e-0548213GO:0001530
GeneOntologyMolecularFunctioncytokine binding

GBP1 GBP2 GBP3 WFIKKN1

1.98e-05157214GO:0019955
GeneOntologyMolecularFunctionG protein activity

GBP1 GBP2 GBP3

3.14e-0559213GO:0003925
GeneOntologyMolecularFunctionendopeptidase inhibitor activity

GBP1 GBP2 GBP3 WFIKKN1

3.39e-05180214GO:0004866
GeneOntologyMolecularFunctionpeptidase inhibitor activity

GBP1 GBP2 GBP3 WFIKKN1

3.94e-05187214GO:0030414
GeneOntologyMolecularFunctionendopeptidase regulator activity

GBP1 GBP2 GBP3 WFIKKN1

5.21e-05201214GO:0061135
GeneOntologyMolecularFunctionpeptidase regulator activity

GBP1 GBP2 GBP3 WFIKKN1

1.35e-04257214GO:0061134
GeneOntologyMolecularFunctionGTPase regulator activity

GBP1 GBP2 GBP3 GIT2 SGSM1

1.50e-04507215GO:0030695
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

GBP1 GBP2 GBP3 GIT2 SGSM1

1.50e-04507215GO:0060589
GeneOntologyMolecularFunctionGDP binding

GBP1 GBP2 GBP3

1.66e-04103213GO:0019003
GeneOntologyMolecularFunctionenzyme regulator activity

GBP1 PDP2 GBP2 GBP3 WFIKKN1 GIT2 SGSM1

4.30e-041418217GO:0030234
GeneOntologyMolecularFunctionenzyme inhibitor activity

GBP1 GBP2 GBP3 WFIKKN1

9.91e-04435214GO:0004857
GeneOntologyMolecularFunctionlipid binding

GBP1 SYT1 GBP2 GBP3 STARD10

3.08e-03988215GO:0008289
GeneOntologyMolecularFunctionmolecular function inhibitor activity

GBP1 GBP2 GBP3 WFIKKN1

3.14e-03596214GO:0140678
GeneOntologyMolecularFunctionubiquitin protein ligase binding

USP19 CTNNB1 SLF1

5.06e-03337213GO:0031625
GeneOntologyMolecularFunctionGTPase activity

GBP1 GBP2 GBP3

5.23e-03341213GO:0003924
GeneOntologyMolecularFunctionubiquitin-like protein ligase binding

USP19 CTNNB1 SLF1

5.98e-03358213GO:0044389
GeneOntologyMolecularFunctionGTP binding

GBP1 GBP2 GBP3

7.95e-03397213GO:0005525
GeneOntologyMolecularFunctionguanyl ribonucleotide binding

GBP1 GBP2 GBP3

1.05e-02439213GO:0032561
GeneOntologyMolecularFunctionguanyl nucleotide binding

GBP1 GBP2 GBP3

1.05e-02439213GO:0019001
GeneOntologyMolecularFunctionpyrophosphatase activity

GBP1 GBP2 GBP3 APTX

1.05e-02839214GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

GBP1 GBP2 GBP3 APTX

1.05e-02840214GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GBP1 GBP2 GBP3 APTX

1.05e-02840214GO:0016818
GeneOntologyMolecularFunctionactin binding

GBP1 GBP2 GBP3

1.32e-02479213GO:0003779
GeneOntologyBiologicalProcesspositive regulation of AIM2 inflammasome complex assembly

GBP1 GBP2 GBP3

4.84e-094233GO:0140973
GeneOntologyBiologicalProcessregulation of AIM2 inflammasome complex assembly

GBP1 GBP2 GBP3

2.42e-086233GO:0140971
GeneOntologyBiologicalProcessAIM2 inflammasome complex assembly

GBP1 GBP2 GBP3

6.76e-088233GO:0140970
GeneOntologyBiologicalProcesspositive regulation of pyroptotic inflammatory response

GBP1 GBP2 GBP3

1.01e-079233GO:0140639
GeneOntologyBiologicalProcesscytolysis in another organism

GBP1 GBP2 GBP3

1.01e-079233GO:0051715
GeneOntologyBiologicalProcesscytolysis

GBP1 GBP2 GBP3

2.65e-0712233GO:0019835
GeneOntologyBiologicalProcessadhesion of symbiont to host

GBP1 GBP2 GBP3

1.36e-0620233GO:0044406
GeneOntologyBiologicalProcesspositive regulation of inflammasome-mediated signaling pathway

GBP1 GBP2 GBP3

3.10e-0626233GO:0141087
GeneOntologyBiologicalProcessdefense response to protozoan

GBP1 GBP2 GBP3

1.08e-0539233GO:0042832
GeneOntologyBiologicalProcesscellular response to interferon-beta

GBP1 GBP2 GBP3

1.26e-0541233GO:0035458
GeneOntologyBiologicalProcessresponse to protozoan

GBP1 GBP2 GBP3

1.35e-0542233GO:0001562
GeneOntologyBiologicalProcesspyroptotic inflammatory response

GBP1 GBP2 GBP3

1.35e-0542233GO:0070269
GeneOntologyBiologicalProcessregulation of inflammasome-mediated signaling pathway

GBP1 GBP2 GBP3

2.03e-0548233GO:0141085
GeneOntologyBiologicalProcessresponse to interferon-beta

GBP1 GBP2 GBP3

2.03e-0548233GO:0035456
GeneOntologyBiologicalProcesspositive regulation of sulfur metabolic process

EIF2AK3 CTNNB1

2.49e-057232GO:0051176
GeneOntologyBiologicalProcessinflammasome-mediated signaling pathway

GBP1 GBP2 GBP3

2.74e-0553233GO:0141084
GeneOntologyBiologicalProcesspositive regulation of pattern recognition receptor signaling pathway

GBP1 GBP2 GBP3

9.06e-0579233GO:0062208
GeneOntologyBiologicalProcesspositive regulation of protein-containing complex assembly

GBP1 GBP2 GBP3 SLF1

1.07e-04227234GO:0031334
GeneOntologyBiologicalProcessregulation of sulfur metabolic process

EIF2AK3 CTNNB1

1.60e-0417232GO:0042762
GeneOntologyBiologicalProcessregulation of sister chromatid cohesion

CTNNB1 SLF1

2.23e-0420232GO:0007063
GeneOntologyBiologicalProcesscellular response to type II interferon

GBP1 GBP2 GBP3

2.69e-04114233GO:0071346
GeneOntologyBiologicalProcessregulation of cytoplasmic pattern recognition receptor signaling pathway

GBP1 GBP2 GBP3

3.86e-04129233GO:0039531
GeneOntologyBiologicalProcessdisruption of cell in another organism

GBP1 GBP2 GBP3

3.86e-04129233GO:0141061
GeneOntologyBiologicalProcesskilling of cells of another organism

GBP1 GBP2 GBP3

3.86e-04129233GO:0031640
GeneOntologyBiologicalProcesspositive regulation of intracellular signal transduction

CD19 GBP1 GBP2 EIF2AK3 GBP3 STARD10 CTNNB1

3.87e-041299237GO:1902533
GeneOntologyBiologicalProcessdisruption of anatomical structure in another organism

GBP1 GBP2 GBP3

4.13e-04132233GO:0141060
GeneOntologyBiologicalProcessregulation of ERAD pathway

EIF2AK3 USP19

4.74e-0429232GO:1904292
GeneOntologyBiologicalProcessresponse to type II interferon

GBP1 GBP2 GBP3

5.01e-04141233GO:0034341
GeneOntologyBiologicalProcessdefense response to Gram-positive bacterium

GBP1 GBP2 GBP3

6.00e-04150233GO:0050830
GeneOntologyBiologicalProcessregulation of skeletal muscle tissue development

USP19 CTNNB1

6.15e-0433232GO:0048641
GeneOntologyBiologicalProcesscellular response to biotic stimulus

GBP1 GBP2 EIF2AK3 GBP3

6.48e-04364234GO:0071216
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

GBP1 GBP2 GBP3 STARD10

1.07e-03416234GO:0030522
GeneOntologyBiologicalProcesscytoplasmic pattern recognition receptor signaling pathway

GBP1 GBP2 GBP3

1.15e-03188233GO:0002753
GeneOntologyBiologicalProcesspositive regulation of inflammatory response

GBP1 GBP2 GBP3

1.24e-03193233GO:0050729
GeneOntologyBiologicalProcessregulation of pattern recognition receptor signaling pathway

GBP1 GBP2 GBP3

1.24e-03193233GO:0062207
GeneOntologyCellularComponenthost cell part

GBP1 GBP2 GBP3

2.32e-086233GO:0033643
GeneOntologyCellularComponenthost intracellular part

GBP1 GBP2 GBP3

2.32e-086233GO:0033646
GeneOntologyCellularComponenthost cell cytoplasm part

GBP1 GBP2 GBP3

2.32e-086233GO:0033655
GeneOntologyCellularComponenthost intracellular region

GBP1 GBP2 GBP3

2.32e-086233GO:0043656
GeneOntologyCellularComponenthost cell cytoplasm

GBP1 GBP2 GBP3

2.32e-086233GO:0030430
GeneOntologyCellularComponentsymbiont-containing vacuole

GBP1 GBP2 GBP3

2.32e-086233GO:0020003
GeneOntologyCellularComponentsymbiont-containing vacuole membrane

GBP1 GBP2 GBP3

2.32e-086233GO:0020005
GeneOntologyCellularComponentsymbiont cell surface

GBP1 GBP2 GBP3

6.49e-088233GO:0106139
GeneOntologyCellularComponentother organism part

GBP1 GBP2 GBP3

9.73e-089233GO:0044217
GeneOntologyCellularComponenthost cellular component

GBP1 GBP2 GBP3

5.25e-0715233GO:0018995
GeneOntologyCellularComponentperinuclear region of cytoplasm

GBP1 GBP2 EIF2AK3 GBP3 CTNNB1 TNRC6A

4.11e-04934236GO:0048471
MousePhenoincreased susceptibility to parasitic infection induced morbidity/mortality

GBP1 GBP2 GBP3

4.78e-0711213MP:0010750
MousePhenoincreased susceptibility to parasitic infection

GBP1 GBP2 GBP3 CTNNB1

9.24e-0691214MP:0005027
MousePhenoincreased heart rate variability

GBP1 GBP2 GBP3

3.00e-0541213MP:0003928
MousePhenoabnormal susceptibility to parasitic infection

GBP1 GBP2 GBP3 CTNNB1

3.24e-05125214MP:0020184
MousePhenoabnormal sinus arrhythmia

GBP1 GBP2 GBP3

2.07e-0478213MP:0004122
DomainGBP_C

GBP1 GBP2 GBP3

1.69e-0710223PF02841
DomainGuanylate-bd_C

GBP1 GBP2 GBP3

2.33e-0711223IPR003191
DomainGBP

GBP1 GBP2 GBP3

2.33e-0711223PF02263
DomainG_GB1_RHD3_dom

GBP1 GBP2 GBP3

2.33e-0711223IPR030386
DomainGuanylate-bd_N

GBP1 GBP2 GBP3

2.33e-0711223IPR015894
DomainG_GB1_RHD3

GBP1 GBP2 GBP3

2.33e-0711223PS51715
DomainAnk_2

BCOR GIT2 SLF1

1.97e-03215223PF12796
DomainAnk

BCOR GIT2 SLF1

2.33e-03228223PF00023
Domain-

BCOR GIT2 SLF1

2.96e-032482231.25.40.20
DomainANK

BCOR GIT2 SLF1

3.06e-03251223SM00248
DomainANK_REPEAT

BCOR GIT2 SLF1

3.13e-03253223PS50088
DomainAnkyrin_rpt-contain_dom

BCOR GIT2 SLF1

3.16e-03254223IPR020683
DomainANK_REP_REGION

BCOR GIT2 SLF1

3.16e-03254223PS50297
DomainAnkyrin_rpt

BCOR GIT2 SLF1

3.45e-03262223IPR002110
Domain-

GBP1 GBP2 GBP3 SULT1C3

1.04e-027462243.40.50.300
DomainP-loop_NTPase

GBP1 GBP2 GBP3 SULT1C3

1.61e-02848224IPR027417
Pubmed

Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa.

GBP1 GBP2 GBP3

2.53e-10323330062052
Pubmed

Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.

GBP1 GBP2 GBP3

2.53e-10323326416908
Pubmed

Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7.

GBP1 GBP2 GBP3

2.53e-10323332354743
Pubmed

GTPase properties of the interferon-induced human guanylate-binding protein 2.

GBP1 GBP2 GBP3

2.53e-1032338706832
Pubmed

Guanylate binding proteins contained in the murine chromosome 3 are important to control mycobacterial infection.

GBP1 GBP2 GBP3

2.53e-10323332620042
Pubmed

[Guanylate-binding protein 2 regulates the maturation of mouse dendritic cells induced by β-glucan].

GBP1 GBP2 GBP3

2.53e-10323329089068
Pubmed

Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication.

GBP1 GBP2 GBP3

2.53e-10323323248289
Pubmed

Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.

GBP1 GBP2 GBP3

2.53e-1032331715024
Pubmed

Two families of GTPases dominate the complex cellular response to IFN-gamma.

GBP1 GBP2 GBP3

2.53e-1032339862701
Pubmed

The interferon (IFN)-induced GTPase, mGBP-2. Role in IFN-gamma-induced murine fibroblast proliferation.

GBP1 GBP2 GBP3

2.53e-10323311726669
Pubmed

GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis.

GBP1 GBP2 GBP3

2.53e-10323338636926
Pubmed

Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2.

GBP1 GBP2 GBP3

2.53e-10323336639389
Pubmed

The interferon-induced GTPase, mGBP-2, confers resistance to paclitaxel-induced cytotoxicity without inhibiting multinucleation.

GBP1 GBP2 GBP3

2.53e-10323316914101
Pubmed

The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.

GBP1 GBP2 GBP3

2.53e-10323322730319
Pubmed

Inhibition of VSV and EMCV replication by the interferon-induced GTPase, mGBP-2: differential requirement for wild-type GTP binding domain.

GBP1 GBP2 GBP3

2.53e-10323315717119
Pubmed

Subtyping of microsatellite stability colorectal cancer reveals guanylate binding protein 2 (GBP2) as a potential immunotherapeutic target.

GBP1 GBP2 GBP3

2.53e-10323335383115
Pubmed

Role of GTP binding, isoprenylation, and the C-terminal α-helices in the inhibition of cell spreading by the interferon-induced GTPase, mouse guanylate-binding protein-2.

GBP1 GBP2 GBP3

2.53e-10323320950129
Pubmed

Interferon regulatory factor 1 is required for mouse Gbp gene activation by gamma interferon.

GBP1 GBP2 GBP3

1.01e-0942337823961
Pubmed

Dnmt1/Tet2-mediated changes in Cmip methylation regulate the development of nonalcoholic fatty liver disease by controlling the Gbp2-Pparγ-CD36 axis.

GBP1 GBP2 GBP3

1.01e-09423336609599
Pubmed

Genomic organization and chromosomal localization of a new member of the murine interferon-induced guanylate-binding protein family.

GBP1 GBP2 GBP3

1.01e-09423310386861
Pubmed

Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of Brucella abortus infection.

GBP1 GBP2 GBP3

1.01e-09423338404575
Pubmed

cDNA for the beta 1 subunit of guanyl nucleotide-binding regulatory proteins from mouse adrenal glands.

GBP1 GBP2 GBP3

1.01e-0942338917111
Pubmed

The Furin Protease Dependence and Antiviral GBP2 Sensitivity of Murine Leukemia Virus Infection Are Determined by the Amino Acid Sequence at the Envelope Glycoprotein Cleavage Site.

GBP1 GBP2 GBP3

1.01e-09423339337476
Pubmed

TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2.

GBP1 GBP2 GBP3

2.52e-09523330858199
Pubmed

Murine GBP-5, a new member of the murine guanylate-binding protein family, is coordinately regulated with other GBPs in vivo and in vitro.

GBP1 GBP2 GBP3

2.52e-09523312396730
Pubmed

Unique features of different members of the human guanylate-binding protein family.

GBP1 GBP2 GBP3

2.52e-09523317266443
Pubmed

Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.

GBP1 GBP2 GBP3

2.52e-09523321151871
Pubmed

Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection.

GBP1 GBP2 GBP3

2.52e-09523331964735
Pubmed

Murine GBP-2: a new IFN-gamma-induced member of the GBP family of GTPases isolated from macrophages.

GBP1 GBP2 GBP3

2.52e-0952339858320
Pubmed

Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene.

GBP1 GBP2 GBP3

5.05e-09623317293456
Pubmed

Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy.

GBP1 GBP2 GBP3

5.05e-09623321757726
Pubmed

The interferon-gamma-induced murine guanylate-binding protein-2 inhibits rac activation during cell spreading on fibronectin and after platelet-derived growth factor treatment: role for phosphatidylinositol 3-kinase.

GBP1 GBP2 GBP3

8.83e-09723320505078
Pubmed

TRIF signaling is required for caspase-11-dependent immune responses and lethality in sepsis.

GBP1 GBP2 GBP3

8.83e-09723330587103
Pubmed

The interferon-gamma-induced GTPase, mGBP-2, inhibits tumor necrosis factor alpha (TNF-alpha) induction of matrix metalloproteinase-9 (MMP-9) by inhibiting NF-kappaB and Rac protein.

GBP1 GBP2 GBP3

8.83e-09723321502320
Pubmed

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.

GBP1 GBP2 GBP3

1.41e-08823316689661
Pubmed

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.

GBP1 GBP2 GBP3

2.12e-08923324739961
Pubmed

Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins.

GBP1 GBP2 GBP3

2.12e-08923333479228
Pubmed

Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.

GBP1 GBP2 GBP3

3.02e-081023328334111
Pubmed

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.

GBP1 GBP2 GBP3

4.15e-081123324715728
Pubmed

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.

GBP1 GBP2 GBP3

4.15e-081123327693356
Pubmed

Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.

GBP1 GBP2 GBP3

4.15e-081123318025219
Pubmed

Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling.

GBP1 GBP2 GBP3

5.54e-081223335906252
Pubmed

LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.

GBP1 GBP2 GBP3

5.54e-081223329459437
Pubmed

Mapping of quantitative trait loci determining NK cell-mediated resistance to MHC class I-deficient bone marrow grafts in perforin-deficient mice.

GBP1 GBP2 GBP3

1.14e-071523317114464
Pubmed

Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida.

GBP1 GBP2 GBP3

1.14e-071523325774716
Pubmed

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.

GBP1 GBP2 GBP3

1.71e-071723325774715
Pubmed

The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation.

GBP1 GBP2 GBP3

2.05e-071823327001747
Pubmed

A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection.

GBP1 GBP2 GBP3

2.43e-071923321551061
Pubmed

Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion.

GBP1 GBP2 GBP3

2.86e-072023332150572
Pubmed

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.

GBP1 GBP2 GBP3

3.33e-072123319158679
Pubmed

Dimerization and its role in GMP formation by human guanylate binding proteins.

GBP1 GBP2

4.18e-07223220923658
Pubmed

The interferon-inducible GBP1 gene: structure and mapping to human chromosome 1.

GBP1 GBP3

4.18e-0722327518790
Pubmed

IFN-γ and TNF-α-induced GBP-1 inhibits epithelial cell proliferation through suppression of β-catenin/TCF signaling.

GBP1 CTNNB1

4.18e-07223222692453
Pubmed

Differential expression of interferon inducible protein: Guanylate binding protein (GBP1 & GBP2) in severe dengue.

GBP1 GBP2

4.18e-07223236460216
Pubmed

Role of beta-catenin in B cell development and function.

CD19 CTNNB1

4.18e-07223218768830
Pubmed

Autophagy restricts Chlamydia trachomatis growth in human macrophages via IFNG-inducible guanylate binding proteins.

GBP1 GBP2

4.18e-07223223086406
Pubmed

Commensal Escherichia coli reduces epithelial apoptosis through IFN-alphaA-mediated induction of guanylate binding protein-1 in human and murine models of developing intestine.

GBP1 GBP2

4.18e-07223220483731
Pubmed

Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.

GBP1 GBP2 GBP3

5.76e-072523335139355
Pubmed

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.

GBP1 GBP2 GBP3

9.13e-072923333278357
Pubmed

GBP1 Facilitates Indoleamine 2,3-Dioxygenase Extracellular Secretion to Promote the Malignant Progression of Lung Cancer.

GBP1 GBP2

1.25e-06323233552086
Pubmed

Identification of paxillin domains interacting with β-catenin.

GIT2 CTNNB1

1.25e-06323222728435
Pubmed

Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR.

CD19 EIF2AK3

2.51e-06423230842412
Pubmed

Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta.

SYT1 CTNNB1

2.51e-06423227036734
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

BCOR EIF2AK3 USP19 SGSM1

9.61e-0537123415747579
Pubmed

Impact of lactobacilli on orally acquired listeriosis.

GBP1 GBP2 GBP3

1.64e-0416223323012479
Pubmed

A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties.

SYT1 CTNNB1

2.05e-043223224192035
Pubmed

KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation.

PDP2 SLF1

2.18e-043323225582440
Pubmed

Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage.

TTLL13 CTNNB1

2.46e-043523237890489
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

BCOR GIT2 CTNNB1 TNRC6A

5.55e-0458823438580884
InteractionGBP3 interactions

GBP1 GBP2 GBP3

1.35e-0710223int:GBP3
InteractionGBP1 interactions

GBP1 GBP2 GBP3

1.26e-0542223int:GBP1
InteractionGBP2 interactions

GBP1 GBP2 GBP3

2.70e-0554223int:GBP2
Cytoband1p22.2

GBP1 GBP2 GBP3

3.57e-07282331p22.2
CytobandEnsembl 112 genes in cytogenetic band chr1p22

GBP1 GBP2 GBP3

4.41e-05137233chr1p22
Cytoband16p11.2

CD19 TNRC6A

4.11e-0319123216p11.2
GeneFamilyAnkyrin repeat domain containing

BCOR GIT2 SLF1

1.40e-03242173403
CoexpressionRUAN_RESPONSE_TO_TNF_UP

GBP1 GBP2 GBP3

7.77e-0721233MM651
CoexpressionGREENBAUM_E2A_TARGETS_DN

GBP1 GBP2 GBP3

8.99e-0722233MM635
CoexpressionRUAN_RESPONSE_TO_TNF_TROGLITAZONE_UP

GBP1 GBP2 GBP3

1.34e-0625233MM672
CoexpressionHE_LIM_SUN_FETAL_LUNG_C2_ADC_2_CELL

GBP1 GBP2 GBP3 STARD10

1.88e-06103234M45742
CoexpressionSASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION

GBP1 GBP2 GBP3

1.27e-0552233MM1118
CoexpressionDELASERNA_MYOD_TARGETS_DN

GBP1 GBP2 GBP3

1.86e-0559233MM659
CoexpressionMIKKELSEN_NPC_LCP_WITH_H3K4ME3

GBP1 GBP2 GBP3

2.16e-0562233MM865
CoexpressionGSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN

EIF2AK3 USP19 GIT2 APTX

2.60e-05200234M3127
CoexpressionGSE22589_HEALTHY_VS_HIV_INFECTED_DC_DN

PAPPA2 SYT1 GBP2 APTX

2.60e-05200234M7807
CoexpressionWUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP

GBP1 GBP2 GBP3

5.37e-0584233MM1049
CoexpressionSEKI_INFLAMMATORY_RESPONSE_LPS_UP

GBP1 GBP2 GBP3

5.96e-0587233MM1253
CoexpressionCASTELLANO_NRAS_TARGETS_UP

GBP1 GBP2 GBP3

6.17e-0588233MM1087
CoexpressionHOWARD_B_CELL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

GBP1 GBP2

6.66e-0514232M41166
CoexpressionQI_PLASMACYTOMA_UP

CD19 GBP1 GBP2 GBP3

8.48e-05271234MM1045
CoexpressionZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_OVERLAP_UP

GBP1 GBP2 GBP3

8.50e-0598233MM460
CoexpressionZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_RENCA_UP

GBP1 GBP2 GBP3

9.03e-05100233MM458
CoexpressionHE_LIM_SUN_FETAL_LUNG_C2_CXCL9_POS_MACROPHAGE_CELL

GBP1 GBP2 GBP3

1.79e-04126233M45721
CoexpressionLI_INDUCED_T_TO_NATURAL_KILLER_UP

TRPM6 GBP1 GBP2 GBP3

2.10e-04343234MM1059
CoexpressionIWANAGA_CARCINOGENESIS_BY_KRAS_DN

GBP1 GBP2 GBP3

2.19e-04135233MM753
CoexpressionICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP

GBP1 GBP2 GBP3

2.34e-04138233MM1047
CoexpressionSALVADOR_MARTIN_PEDIATRIC_TBD_ANTI_TNF_THERAPY_NONRESPONDER_POST_TREATMENT_UP

GBP1 GBP2

2.36e-0426232M41741
CoexpressionMIKKELSEN_MEF_LCP_WITH_H3K4ME3

GBP1 GBP2 GBP3

2.55e-04142233MM840
CoexpressionTABULA_MURIS_SENIS_LIMB_MUSCLE_ENDOTHELIAL_CELL_AGEING

GBP1 GBP2 GBP3

2.71e-04145233MM3744
CoexpressionTABULA_MURIS_SENIS_LUNG_BRONCHIAL_SMOOTH_MUSCLE_CELL_AGEING

GBP1 GBP2 GBP3

3.36e-04156233MM3763
CoexpressionHOWARD_DENDRITIC_CELL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

GBP1 GBP2 GBP3

3.55e-04159233M40998
CoexpressionGSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_UP

GBP2 GBP3 APTX

3.82e-04163233M8663
CoexpressionSOBOLEV_PBMC_PANDEMRIX_AGE_18_64YO_7DY_DN

GBP1 GBP2

3.83e-0433232M41194
CoexpressionGSE37534_PIOGLITAZONE_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN

PDP2 APTX CTNNB1

3.95e-04165233M8992
CoexpressionMIKKELSEN_MCV6_LCP_WITH_H3K4ME3

GBP1 GBP2 GBP3

4.62e-04174233MM836
CoexpressionICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP

GBP1 GBP2 GBP3

4.77e-04176233MM1048
CoexpressionHOWARD_T_CELL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

GBP1 GBP2

6.21e-0442232M41024
CoexpressionGSE3982_EOSINOPHIL_VS_TH2_UP

SYT1 USP19 GIT2

6.43e-04195233M5424
CoexpressionGSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_DN

USP19 GIT2 TNRC6A

6.63e-04197233M5853
CoexpressionGSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_DN

USP19 GIT2 TNRC6A

6.63e-04197233M5879
CoexpressionGSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN

USP19 GIT2 TNRC6A

6.73e-04198233M5861
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_14_PRECICTIVE_ICB_RESPONSE

GBP1 GBP2 GBP3

6.73e-04198233MM17083
CoexpressionGSE17721_LPS_VS_GARDIQUIMOD_24H_BMDC_UP

GBP2 USP19 CTNNB1

6.83e-04199233M4063
CoexpressionGSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN

USP19 GIT2 TNRC6A

6.83e-04199233M5874
CoexpressionGSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN

GBP1 GBP2 CTNNB1

6.83e-04199233M5264
CoexpressionGSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_DN

BCOR GBP1 GBP2

6.93e-04200233M3276
CoexpressionGSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN

CD19 USP19 TNRC6A

6.93e-04200233M8506
CoexpressionKRIEG_KDM3A_TARGETS_NOT_HYPOXIA

GBP1 GBP3 APTX

6.93e-04200233M2468
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_8_PRECICTIVE_ICB_RESPONSE

GBP1 GBP2 GBP3

6.93e-04200233MM17082
CoexpressionGSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_DN

PAPPA2 GBP1 GBP2

6.93e-04200233M9593
CoexpressionAFFAR_YY1_TARGETS_UP

GBP1 GBP2 GBP3

8.77e-04217233MM1156
CoexpressionHOWARD_MONOCYTE_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

GBP1 GBP2 GBP3

1.05e-03231233M40995
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP

GBP1 GBP2 GBP3

1.10e-03235233MM978
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BCOR GBP1 GBP2 GBP3

1.39e-06163234130c84bca3f72ab7d1a4fee2990c3d01600318ed
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 GBP3 SGSM1

3.65e-051262334eeea015efe17e0aae5bd76b71fa70b5149dfada
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BCOR WFIKKN1 SULT1C3

7.01e-05157233bd45590da540a557dc8096980a45220fccb99505
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BCOR WFIKKN1 SULT1C3

7.01e-0515723300c9a58b033b8b95b0d838f233dd077b62d8b02a
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGSM1 CTNNB1 ZSWIM1

7.42e-05160233a76ad44b5f25f59d6b9333fb45f8bb96196a3090
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGSM1 CTNNB1 ZSWIM1

7.42e-05160233af84da18c85037f49f55e8958f00f12140226982
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGSM1 CTNNB1 ZSWIM1

7.42e-05160233f7ca98beaa24f9674d503588eb15d341c4135d77
ToppCellTCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type-6|TCGA-Adrenal / Sample_Type by Project: Shred V9

GBP2 STARD10 ZSWIM1

7.70e-051622330e8fb83acb8ea9905cc3ca985feb8a00931549ff
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BCOR GBP1 GBP3

8.13e-05165233436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BCOR GBP1 GBP3

8.13e-05165233242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 GBP2 GBP3

8.42e-05167233774f3264318b002d0df5d06d41d645366038d0bf
ToppCelldroplet-Marrow-nan-24m-Hematologic-erythroid_progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD19 GBP2 GBP3

9.19e-05172233910ec7794ea4000db4ef1e2c34e08dbc0243df2c
ToppCelldroplet-Marrow-nan-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD19 GBP2 STARD10

9.35e-0517323337825d0dda028cf677ff6ff16ea58bff75cb25a7
ToppCelldroplet-Marrow-nan-24m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD19 GBP2 STARD10

9.35e-0517323335dc897e06f905419d44093a92170d2cec35dd51
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

GBP1 GBP2 GBP3

1.03e-04179233af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell10x5'-Liver-Lymphocytic_B-Memory_B_cells|Liver / Manually curated celltypes from each tissue

CD19 SYT1 EIF2AK3

1.07e-04181233a9f4df288c34e3b2b6ed861ac6cda970c3ee08b1
ToppCellCOVID-19_Severe-Neutrophil|COVID-19_Severe / Disease condition and Cell class

TRPM6 GBP1 GBP2

1.07e-04181233aa5e5fb0308b5e2ef918548c85529c9a433c57f5
ToppCellCOVID-19_Severe-Neutrophil-|COVID-19_Severe / Disease condition and Cell class

TRPM6 GBP1 GBP2

1.07e-041812335e5101195d5ff8c8ea7ddcf0bc4f4e03e64c01e0
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

GBP1 GBP2 GBP3

1.10e-041832338f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD19 SYT1 EIF2AK3

1.12e-04184233d18e94839a62fca536ae1630c154e5d0aafc44c5
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP1 GBP2 GBP3

1.14e-04185233f30fb9d75cdb757b206312992aaf7485bc900f96
ToppCellfacs-Heart-LA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGSM1 STARD10 ZSWIM1

1.16e-04186233246503fd4e6ae24041c606b069eb5fb313e60f73
ToppCellfacs-Heart-LA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGSM1 STARD10 ZSWIM1

1.16e-04186233ef93ac469eb4f63db036f14b442c1503b8c6de38
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

GBP1 GBP2 GBP3

1.20e-041882336f8946d4710f6e32c937213f99b790b098b8819c
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRPM6 GBP1 GBP2

1.20e-04188233aa46073e2940dc1d2020b2e259bf0fc06cb990ee
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TRPM6 GBP1 GBP2

1.20e-0418823304814b78da936a51a497e23060d19ca0d619e250
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 PAPPA2 SGSM1

1.21e-04189233f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell10x5'-Liver-Lymphocytic_B|Liver / Manually curated celltypes from each tissue

CD19 SYT1 EIF2AK3

1.21e-041892331ebff8185060d78f27f8d887e9adaa5f8faf2196
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 PAPPA2 SGSM1

1.23e-04190233b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

GBP1 GBP2 GBP3

1.25e-041912332da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GBP1 SYT1 GBP2

1.25e-0419123389d03c4133dda852a3713c0902a7d67941cf5b21
ToppCellLeuk-UTI|World / Disease, Lineage and Cell Type

GBP1 GBP2 GBP3

1.29e-0419323326119a0b5d7684022fd16b8b73a0ef5a7d70f3d1
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-STAT1+_Naive_B|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD19 GBP1 GBP2

1.31e-04194233a478947715e7ef7994040c7c661ff3a3e776b5fc
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

GBP1 GBP2 GBP3

1.33e-04195233b64d9e1a8834401b4dc501566546647754ae21fc
ToppCell15-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

GBP1 SYT1 GBP2

1.35e-041962330e45817625b96d21a8cc4dfbbd465ee6403b6802
ToppCellmild-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

GBP1 GBP2 GBP3

1.35e-04196233ded44b38ea489946e9eedfe752b5a9fde9149c16
ToppCellsevere-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

GBP1 GBP2 GBP3

1.37e-04197233c8a90d82170cf20e14aebecddcf7cc0ca56cda87
ToppCellCV-Mild-1|CV / Virus stimulation, Condition and Cluster

GBP1 GBP2 GBP3

1.39e-041982334b078714c49e7befb7b113d72485e712236d35fa
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GBP1 GBP2 GBP3

1.41e-04199233841338719d042247966867ac608146395eb8c4d9
ToppCellSepsis-Leuk-UTI|Sepsis / Disease, condition lineage and cell class

GBP1 GBP2 GBP3

1.44e-042002337d92b24c0c888dd46e40b7e3c6c2645c3604f132
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GBP1 GBP2 GBP3

1.44e-042002330f6620a5baace704518d42fa2f3f90751240f7dd
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-B-B_cell-B_naive|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GIT2 ZSWIM1

1.22e-0310123286acaa2502f61baa714ae988b73e3e73a71e897e
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Cd74|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GBP2 GBP3

1.58e-031152324c7d78a246f1b44846fb959359515ef185530053
ToppCellControl-CD4+_T_activated|Control / Disease condition and Cell class

PAPPA2 GBP1

1.61e-03116232e3d1a90a229f5697b2b715574bb96790a435f73b
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PAPPA2 GBP1

1.66e-03118232f76fc6db7368a1e8e5e4f8535fc3dc78afe13b9b
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PAPPA2 GBP1

1.66e-031182320dcac16eea8e7978de370a815da9a0cdd212598e
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PAPPA2 GBP1

1.66e-031182327da3957d102e9f9825fc2609d6d0bd9ca6a3fba4
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PAPPA2 GBP1

1.66e-03118232c5c6724e0e526d7c2fc8cabff4a112a900ec997f
ToppCellControl-Lymphoid_T/NK-CD4+_T_activated|Control / Disease group, lineage and cell class

PAPPA2 GBP1

1.69e-03119232d7352d0dafbb664619b7a1e3cd07b159fdfec197
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Intermediate|GW19 / Sample Type, Dataset, Time_group, and Cell type.

PAPPA2 GBP1

1.72e-03120232eb5b88c47dd4a6f9b55ace24f19d4e81d4ed31e1
ToppCellEndothelial-Endothelial-F|Endothelial / shred on cell class and cell subclass (v4)

GBP2 GBP3

1.78e-031222322cb8bb63c69aed4d4504b9d97219b8707666f950
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM6 WFIKKN1

1.84e-03124232d88bce8a4f023d5b617b2e8e372a94bd1248d20d
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 GBP3

1.86e-0312523235042ed43045dddc341b76cc5f9fe31b5ba0abb8
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Stem_cells-neuroepithelial-like_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

WFIKKN1 GIT2

1.92e-031272329071cd0953c8bb6746dc9cd13d153e3d6ef40b08
ToppCellASK452-Epithelial-Secretory|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

SYT1 GIT2

2.08e-0313223249ba24e24b3127b5257a88a0ee0246c9843c580a
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Proliferative_AT1_Progenitor|E16.5-samps / Age Group, Lineage, Cell class and subclass

BCOR ZSWIM1

2.11e-03133232b0d3ac5abd9ebd490db46a3ef2e4ae88c4bf4e34
ToppCellMild/Remission-B_intermediate-14|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SGSM1 ZSWIM1

2.14e-031342325bd1e3fa6278facd9e949e9e5e244e700190126b
ToppCellMild/Remission-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CD19 SYT1

2.20e-031362321b3c6edcbe0eb674d2d9c838e83ebe2b93e3eec1
ToppCellPND07-28-samps-Lymphocyte-B_cell-B_cell_2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CD19 EIF2AK3

2.23e-031372322544d1256f11da6e3bad24a871b2253e0ab20d01
ToppCellPND07-28-samps-Lymphocyte-B_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CD19 EIF2AK3

2.23e-03137232874e2eaa7846a2832f46b77c726d79f220a4a1cd
ToppCellEndothelial-F|World / shred on cell class and cell subclass (v4)

GBP2 GBP3

2.30e-0313923232d3c5d35e6c4205711c3500d736fd108443e6b4
ToppCellMild/Remission-B_intermediate-14|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SGSM1 ZSWIM1

2.36e-0314123269e32125a0e8f0c8561e5e7a93607f368f09546f
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRPM6 SYT1

2.40e-03142232191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD19 SYT1

2.40e-0314223266135fee18448cc09a78bc6ede05afd63c72ae21
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TRPM6 SYT1

2.43e-03143232b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 EIF2AK3

2.46e-031442325665dd2839b6c8ddbf5ddb2d22e1ee6073f74c3b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD19 SYT1

2.46e-03144232fca32b38d23fa4d213e553b929604a2796e9a929
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD19 ZSWIM1

2.50e-03145232b17699f7f98d2361a4d26c26f52db05e7ff69dff
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYT1 ZSWIM1

2.60e-031482326ffa212f0cc44c40d2143816dc6cfd82fbf09a33
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TRPM6 GBP3

2.63e-03149232d9c47f523c75ddcd6131e45d2ffc24b970932cae
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Lymphocytic-B_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD19 WFIKKN1

2.63e-03149232a6e192bf9bcf3b219e618c465bc451f7c86f49f1
ToppCellPND28|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD19 GBP2

2.63e-03149232d3a025440c8ad284a9291c902403e5888d28e90b
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD19 ZSWIM1

2.63e-0314923254c9c6282f5f5de43dfaf2972fab3e3dcf9838a3
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD19 ZSWIM1

2.63e-0314923214d2e8cab97108d8fa94e540c1957b73ed32dc73
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WFIKKN1 APTX

2.63e-03149232efa30fcd9370f98eb7445f295eb4d0305ff455c3
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

PAPPA2 SLF1

2.70e-03151232999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYT1 ZSWIM1

2.70e-03151232ea62e92ccb984f44559b434f35c1c4450767c8f1
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRPM6 USP19

2.74e-031522320652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCellMS-CD4-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

GBP1 GBP2

2.74e-03152232b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD19 WFIKKN1

2.77e-03153232a8f83ec640fae51d4fba34b92e3d6cca4999e930
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_3|367C / Donor, Lineage, Cell class and subclass (all cells)

DIAPH2-AS1 GBP2

2.77e-03153232da1bff9928d8c61bb1c389d45fd897cfa4bed023
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-B_lymphocytic-memory_B_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CD19 SYT1

2.85e-03155232d336559092563b0d7776eef873f1d2759aca45f7
ToppCellAdult-Immune-B_cell-D122|Adult / Lineage, Cell type, age group and donor

CD19 SYT1

2.85e-031552325857aebd43b901fc9f8c46f2d628582969db9e6a
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD19 SYT1

2.85e-0315523272a19a9ecfd13f6769c4b447d3ce01a855ec6ec7
ToppCellHealthy_Control-Myeloid-Macrophages-FCN1_high|Healthy_Control / Condition, Lineage, Cell class and cell subclass

DIAPH2-AS1 GBP1

2.85e-03155232cd2ccb4632713b4def3a1064599b78207e2e44c0
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD19 SYT1

2.88e-03156232d81e78bec5c8a3f3ec9e1447ebab2c5805b815eb
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD19 SYT1

2.88e-031562324e4b94580969a9736ca28df79715535a4bd1f9b2
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-Treg|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DIAPH2-AS1 GBP2

2.92e-031572322c767c526abcc8adea6ec4eb2cc333060bb213b5
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 SGSM1

2.92e-03157232a426c54fd1545093d41426e9620862f71bd06f6b
ToppCellControl-Lymphocyte-T_NK-dnT|Control / Disease, Lineage and Cell Type

GBP2 WFIKKN1

2.95e-031582327a2fad6426549d910834debfe5e102fe2ab5976d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDP2 WFIKKN1

2.95e-031582327f5426585d0d299d2b48e5fcb349950feffdef33
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 SGSM1

2.95e-031582327960337d87afecf2692ab65e5991f052ceddfacc
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-3|TCGA-Pancreas / Sample_Type by Project: Shred V9

DIAPH2-AS1 STARD10

2.95e-03158232ec1a71b8f46179642b5af20e27764bb43c4b8e99
ToppCellAdult-Immune-mast_cell-D175|Adult / Lineage, Cell type, age group and donor

PAPPA2 STARD10

2.99e-031592329f53fe2e0f25448d62a591c8e528e9a49b5400d5
ToppCell10x5'-Lung-Lymphocytic_B-ABC_aged-B_memory|Lung / Manually curated celltypes from each tissue

CD19 SYT1

2.99e-03159232d3202ddc291b8686dbe67690df13c7daffec2199
ToppCellFLU-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

GBP1 GBP3

2.99e-0315923297c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCellFLU-Healthy-1|FLU / Virus stimulation, Condition and Cluster

GBP1 GBP3

2.99e-03159232fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCellfacs-Trachea-nan-18m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD19 PDP2

3.03e-031602325c9281706009558c8361bfa76169f43ffc0f7947
ToppCell3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STARD10 CTNNB1

3.03e-031602326005948e400e781cdb876ba350b3ec8991e3945f
ToppCellmild_COVID-19_(asymptomatic)-B_intermediate|World / disease group, cell group and cell class (v2)

CD19 SYT1

3.03e-031602326722934e153b72039c3c4308557d0ef879a30638
ComputationalImmune response and Ag processing and presentation.

CD19 GBP1 GBP2

4.13e-04126133MODULE_345
ComputationalGenes in the cancer module 292.

CD19 GBP1 GBP2

5.16e-04136133MODULE_292
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

GBP1 GBP2

1.60e-0350132GAVISH_3CA_METAPROGRAM_MACROPHAGES_INTERFERON
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

GBP1 GBP2

1.60e-0350132GAVISH_3CA_METAPROGRAM_ENDOTHELIAL_INTERFERON
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

GBP1 GBP2

1.60e-0350132GAVISH_3CA_METAPROGRAM_FIBROBLASTS_INTERFERON
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

GBP1 GBP2

1.60e-0350132GAVISH_3CA_MALIGNANT_METAPROGRAM_17_INTERFERON_MHC_II_1
DiseaseAcute kidney injury

GBP1 GBP3

1.72e-0425232HP_0001919
DiseaseBilateral Wilms Tumor

BCOR CTNNB1

2.33e-0429232C2930471
DiseaseMyocardial Ischemia

GBP2 EIF2AK3 CTNNB1

3.38e-04176233C0151744
DiseaseNephroblastoma

BCOR CTNNB1

3.60e-0436232C0027708
Diseasecognitive function measurement

CD19 SYT1 SGSM1 STARD10 CTNNB1 TNRC6A

6.44e-041434236EFO_0008354
Diseasecortical surface area measurement, neuroimaging measurement

SYT1 SLF1 TNRC6A

7.10e-04227233EFO_0004346, EFO_0010736
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

SYT1 CTNNB1 TNRC6A

3.53e-03398233EFO_0003756, EFO_0003888, EFO_0004337
Diseasecolorectal cancer (is_implicated_in)

BCOR CTNNB1

3.99e-03121232DOID:9256 (is_implicated_in)
Diseaseverbal-numerical reasoning measurement

SYT1 TNRC6A

4.66e-03131232EFO_0008394

Protein segments in the cluster

PeptideGeneStartEntry
HPKLWPQLAGTKTLH

DIAPH2-AS1

6

Q14236
LPTIKWKPLIHSPSR

EIF2AK3

426

Q9NZJ5
PSIPQLKEHLRKHWT

APTX

341

Q7Z2E3
SQVRHLKHTPWPPTL

GIT2

46

Q14161
IPPLVHCADKSLPWK

BCOR

276

Q6W2J9
LPVVVKLLHPPSHWP

CTNNB1

491

P35222
KLLHPPSHWPLIKAT

CTNNB1

496

P35222
WCVPHPKKPGHILVL

GBP1

81

P32455
WCVPHPKKPEHTLVL

GBP2

81

P32456
WCVPHPKKPEHTLVL

GBP3

81

Q9H0R5
PWPKHSLKHRVKKSP

PAPPA2

221

Q9BXP8
KPLLPILHWLKHPGD

PDP2

181

Q9P2J9
PLSWTHVHPKGPKSL

CD19

211

P15391
LHKIPLPPWALIAIA

SYT1

51

P21579
THLPSHLIPPSIWKE

SULT1C3

116

Q6IMI6
KQKHLPHFKPWLHPE

STARD10

226

Q9Y365
HLTLPKKVPMLTWPS

USP19

186

O94966
HEKPWLPPPLILLSH

TRPM6

1096

Q9BX84
PKLPNLSPLAIKHLW

SGSM1

116

Q2NKQ1
SALLHLHPPWKSPAM

SLF1

471

Q9BQI6
HLHIVPCKHVLSWPP

WFIKKN1

151

Q96NZ8
IPPAKLPELHSHWLL

ZSWIM1

221

Q9BR11
TSLAHELWKVPLPPK

TNRC6A

1711

Q8NDV7
HKLKPWLLEVNHSPS

TTLL13

381

A6NNM8