Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	MAP kinase kinase kinase activity	MAP3K20 MAP3K15 MAP3K6 MAP3K5	5.98e-06	27	89	4	GO:0004709
GeneOntologyMolecularFunction	magnesium ion binding	ADCY10 MAP3K20 MAP3K6 CDC42BPB MAP3K5 DYRK2 ADSS1	1.18e-04	247	89	7	GO:0000287
GeneOntologyMolecularFunction	protein serine kinase activity	OBSCN MAP3K20 MAP3K15 MAP3K6 CDC42BPB PLK4 MAP3K5 DYRK2	2.17e-04	363	89	8	GO:0106310
GeneOntologyMolecularFunction	protein kinase activity	OBSCN MAP3K20 KDR MAP3K15 KIT MAP3K6 CDC42BPB PLK4 MAP3K5 DYRK2	3.36e-04	600	89	10	GO:0004672
GeneOntologyBiologicalProcess	cell-cell adhesion	SRPX2 CD5 HLA-DMB PCDH11Y PCDHB10 PCDH11X IGSF9 IGSF9B ATP1B2 KIT OLR1 SVEP1 NOTCH1 CDHR4 CD276 CFHR4 SIRPG	3.02e-06	1077	89	17	GO:0098609
GeneOntologyBiologicalProcess	multi-pass transmembrane protein insertion into ER membrane	NOMO2 NOMO3 NOMO1	6.40e-06	9	89	3	GO:0160063
GeneOntologyCellularComponent	multi-pass translocon complex	NOMO2 NOMO3 NOMO1	5.95e-06	9	88	3	GO:0160064
GeneOntologyCellularComponent	ER membrane insertion complex	NOMO2 NOMO3 NOMO1	2.54e-05	14	88	3	GO:0072379
Domain	Ig-like_fold	FNDC3B FNDC1 COL12A1 PIGR HLA-DMB NOMO2 COL20A1 OBSCN IGSF9 KDR ILDR1 IGSF9B NFAM1 KIT USH2A NOMO3 NOMO1 CD276 SIRPG	6.98e-10	706	89	19	IPR013783
Domain	-	FNDC3B FNDC1 COL12A1 PIGR HLA-DMB NOMO2 COL20A1 OBSCN IGSF9 KDR ILDR1 IGSF9B KIT USH2A NOMO3 NOMO1 CD276 SIRPG	1.83e-09	663	89	18	2.60.40.10
Domain	Sushi	SRPX2 CSMD1 CSMD3 SVEP1 MASP2 SEZ6 CFHR4	4.93e-09	52	89	7	PF00084
Domain	CCP	SRPX2 CSMD1 CSMD3 SVEP1 MASP2 SEZ6 CFHR4	6.48e-09	54	89	7	SM00032
Domain	SUSHI	SRPX2 CSMD1 CSMD3 SVEP1 MASP2 SEZ6 CFHR4	8.42e-09	56	89	7	PS50923
Domain	Sushi_SCR_CCP_dom	SRPX2 CSMD1 CSMD3 SVEP1 MASP2 SEZ6 CFHR4	9.56e-09	57	89	7	IPR000436
Domain	DUF4071	MAP3K15 MAP3K6 MAP3K5	1.05e-07	3	89	3	IPR025136
Domain	DUF4071	MAP3K15 MAP3K6 MAP3K5	1.05e-07	3	89	3	PF13281
Domain	DUF2012	NOMO2 NOMO3 NOMO1	4.17e-07	4	89	3	PF09430
Domain	DUF2012	NOMO2 NOMO3 NOMO1	4.17e-07	4	89	3	IPR019008
Domain	fn3	FNDC3B FNDC1 COL12A1 COL20A1 OBSCN IGSF9 IGSF9B USH2A	1.05e-06	162	89	8	PF00041
Domain	FN3	FNDC3B FNDC1 COL12A1 COL20A1 OBSCN IGSF9 IGSF9B USH2A	2.84e-06	185	89	8	SM00060
Domain	FN3	FNDC3B FNDC1 COL12A1 COL20A1 OBSCN IGSF9 IGSF9B USH2A	4.87e-06	199	89	8	PS50853
Domain	Carb-bd-like_fold	NOMO2 NOMO3 NOMO1	5.76e-06	8	89	3	IPR013784
Domain	FN3_dom	FNDC3B FNDC1 COL12A1 COL20A1 OBSCN IGSF9 IGSF9B USH2A	6.99e-06	209	89	8	IPR003961
Domain	IG_LIKE	PIGR HLA-DMB OBSCN IGSF9 KDR ILDR1 IGSF9B NFAM1 KIT CD276 SIRPG	2.13e-05	491	89	11	PS50835
Domain	Sacchrp_dh_NADP	SCCPDH AASS	2.25e-05	2	89	2	IPR005097
Domain	Sacchrp_dh_NADP	SCCPDH AASS	2.25e-05	2	89	2	PF03435
Domain	Ig-like_dom	PIGR HLA-DMB OBSCN IGSF9 KDR ILDR1 IGSF9B NFAM1 KIT CD276 SIRPG	2.66e-05	503	89	11	IPR007110
Domain	CarboxyPept_regulatory_dom	NOMO2 NOMO3 NOMO1	2.89e-05	13	89	3	IPR014766
Domain	-	NOMO2 NOMO3 NOMO1	2.89e-05	13	89	3	2.60.40.1120
Domain	IGv	PIGR OBSCN IGSF9B CD276 SIRPG	2.91e-05	75	89	5	SM00406
Domain	IG	PIGR OBSCN IGSF9 KDR ILDR1 IGSF9B NFAM1 KIT CD276 SIRPG	3.16e-05	421	89	10	SM00409
Domain	Ig_sub	PIGR OBSCN IGSF9 KDR ILDR1 IGSF9B NFAM1 KIT CD276 SIRPG	3.16e-05	421	89	10	IPR003599
Domain	ig	PIGR HLA-DMB OBSCN KDR KIT CD276 SIRPG	3.44e-05	190	89	7	PF00047
Domain	Immunoglobulin	PIGR HLA-DMB OBSCN KDR KIT CD276 SIRPG	3.44e-05	190	89	7	IPR013151
Domain	PROTEIN_KINASE_ATP	OBSCN MAP3K20 KDR MAP3K15 KIT MAP3K6 CDC42BPB PLK4 MAP3K5 DYRK2	6.54e-05	459	89	10	PS00107
Domain	HYR	SRPX2 SVEP1	6.72e-05	3	89	2	PS50825
Domain	HYR	SRPX2 SVEP1	6.72e-05	3	89	2	PF02494
Domain	HYR_dom	SRPX2 SVEP1	6.72e-05	3	89	2	IPR003410
Domain	CarboxyPept-like_regulatory	NOMO2 NOMO3 NOMO1	6.78e-05	17	89	3	IPR008969
Domain	Protein_kinase_ATP_BS	OBSCN KDR MAP3K15 KIT MAP3K6 CDC42BPB PLK4 MAP3K5 DYRK2	8.07e-05	379	89	9	IPR017441
Domain	CUB	CSMD1 CSMD3 MASP2 SEZ6	8.66e-05	49	89	4	PF00431
Domain	CUB	CSMD1 CSMD3 MASP2 SEZ6	9.38e-05	50	89	4	SM00042
Domain	-	CSMD1 CSMD3 MASP2 SEZ6	1.10e-04	52	89	4	2.60.120.290
Domain	Prot_kinase_dom	OBSCN MAP3K20 KDR MAP3K15 KIT MAP3K6 CDC42BPB PLK4 MAP3K5 DYRK2	1.10e-04	489	89	10	IPR000719
Domain	PROTEIN_KINASE_DOM	OBSCN MAP3K20 KDR MAP3K15 KIT MAP3K6 CDC42BPB PLK4 MAP3K5 DYRK2	1.18e-04	493	89	10	PS50011
Domain	CUB	CSMD1 CSMD3 MASP2 SEZ6	1.18e-04	53	89	4	PS01180
Domain	CUB_dom	CSMD1 CSMD3 MASP2 SEZ6	1.57e-04	57	89	4	IPR000859
Domain	Protocadherin	PCDH11Y PCDH11X	2.22e-04	5	89	2	PF08374
Domain	Protocadherin	PCDH11Y PCDH11X	2.22e-04	5	89	2	IPR013585
Domain	SAM/pointed	MAP3K20 ETS2 MAP3K15 MAP3K6 MAP3K5	2.42e-04	117	89	5	IPR013761
Domain	Kinase-like_dom	OBSCN MAP3K20 KDR MAP3K15 KIT MAP3K6 CDC42BPB PLK4 MAP3K5 DYRK2	2.54e-04	542	89	10	IPR011009
Domain	S_TKc	OBSCN MAP3K20 MAP3K15 MAP3K6 CDC42BPB PLK4 MAP3K5 DYRK2	3.14e-04	359	89	8	SM00220
Domain	PROTEIN_KINASE_ST	OBSCN MAP3K20 MAP3K15 MAP3K6 CDC42BPB PLK4 MAP3K5 DYRK2	3.32e-04	362	89	8	PS00108
Domain	Ig_V-set	PIGR OBSCN KDR IGSF9B CD276 SIRPG	3.78e-04	199	89	6	IPR013106
Domain	Tyr_kinase_rcpt_3_CS	KDR KIT	6.17e-04	8	89	2	IPR001824
Domain	RECEPTOR_TYR_KIN_III	KDR KIT	6.17e-04	8	89	2	PS00240
Domain	EGF_CA	NID1 SVEP1 NOTCH1 MASP2	7.60e-04	86	89	4	PF07645
Domain	IGc2	OBSCN IGSF9 KDR IGSF9B KIT CD276	9.06e-04	235	89	6	SM00408
Domain	Ig_sub2	OBSCN IGSF9 KDR IGSF9B KIT CD276	9.06e-04	235	89	6	IPR003598
Domain	PROTEIN_KINASE_TYR	OBSCN KDR KIT PLK4	1.19e-03	97	89	4	PS00109
Domain	EGF_Ca-bd_CS	NID1 SVEP1 NOTCH1 MASP2	1.19e-03	97	89	4	IPR018097
Domain	Tyr_kinase_AS	OBSCN KDR KIT PLK4	1.19e-03	97	89	4	IPR008266
Domain	-	NID1 SVEP1	1.20e-03	11	89	2	2.40.155.10
Domain	GFP-like	NID1 SVEP1	1.20e-03	11	89	2	IPR023413
Domain	EGF_CA	NID1 SVEP1 NOTCH1 MASP2	1.28e-03	99	89	4	PS01187
Domain	ASX_HYDROXYL	NID1 SVEP1 NOTCH1 MASP2	1.33e-03	100	89	4	PS00010
Domain	Ser/Thr_kinase_AS	OBSCN MAP3K20 MAP3K15 MAP3K6 CDC42BPB MAP3K5 DYRK2	1.58e-03	357	89	7	IPR008271
Domain	EGF-type_Asp/Asn_hydroxyl_site	NID1 SVEP1 NOTCH1 MASP2	1.65e-03	106	89	4	IPR000152
Domain	Cadherin_CS	PCDH11Y PCDHB10 PCDH11X CDHR4	1.83e-03	109	89	4	IPR020894
Domain	V-set	PIGR KDR IGSF9B CD276 SIRPG	1.87e-03	184	89	5	PF07686
Domain	CADHERIN_1	PCDH11Y PCDHB10 PCDH11X CDHR4	2.09e-03	113	89	4	PS00232
Domain	Cadherin	PCDH11Y PCDHB10 PCDH11X CDHR4	2.09e-03	113	89	4	PF00028
Domain	CADHERIN_2	PCDH11Y PCDHB10 PCDH11X CDHR4	2.16e-03	114	89	4	PS50268
Domain	-	PCDH11Y PCDHB10 PCDH11X CDHR4	2.16e-03	114	89	4	2.60.40.60
Domain	CA	PCDH11Y PCDHB10 PCDH11X CDHR4	2.23e-03	115	89	4	SM00112
Domain	Pkinase	OBSCN MAP3K15 MAP3K6 CDC42BPB PLK4 MAP3K5 DYRK2	2.29e-03	381	89	7	PF00069
Domain	Cadherin-like	PCDH11Y PCDHB10 PCDH11X CDHR4	2.30e-03	116	89	4	IPR015919
Domain	IGc1	HLA-DMB CD276 SIRPG	2.42e-03	56	89	3	SM00407
Domain	VWA	COL12A1 COL20A1 SVEP1	2.42e-03	56	89	3	PF00092
Domain	Cadherin	PCDH11Y PCDHB10 PCDH11X CDHR4	2.45e-03	118	89	4	IPR002126
Domain	Laminin_G	COL12A1 COL20A1 USH2A	2.67e-03	58	89	3	IPR001791
Domain	Ig_C1-set	HLA-DMB CD276 SIRPG	2.67e-03	58	89	3	IPR003597
Domain	EGF_CA	NID1 SVEP1 NOTCH1 MASP2	2.76e-03	122	89	4	SM00179
Domain	EGF-like_Ca-bd_dom	NID1 SVEP1 NOTCH1 MASP2	2.93e-03	124	89	4	IPR001881
Domain	Pkinase_Tyr	MAP3K20 KDR KIT PLK4	3.37e-03	129	89	4	PF07714
Domain	Cadherin_2	PCDH11Y PCDHB10 PCDH11X	3.69e-03	65	89	3	PF08266
Domain	Cadherin_N	PCDH11Y PCDHB10 PCDH11X	3.69e-03	65	89	3	IPR013164
Domain	Ser-Thr/Tyr_kinase_cat_dom	MAP3K20 KDR KIT PLK4	4.29e-03	138	89	4	IPR001245
Pubmed	Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.	NOMO2 NOMO3 NOMO1	1.73e-08	3	91	3	36011023
Pubmed	Structure-based mechanism of preferential complex formation by apoptosis signal-regulating kinases.	MAP3K15 MAP3K6 MAP3K5	1.73e-08	3	91	3	32156783
Pubmed	ASK family kinases mediate cellular stress and redox signaling to circadian clock.	MAP3K15 MAP3K6 MAP3K5	1.73e-08	3	91	3	29555767
Pubmed	Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.	NOMO2 NOMO3 NOMO1	1.73e-08	3	91	3	25576386
Pubmed	Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.	NOMO2 NOMO3 NOMO1	6.92e-08	4	91	3	31833031
Pubmed	A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.	NOMO2 NOMO3 NOMO1	6.92e-08	4	91	3	9267806
Pubmed	Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.	NOMO2 NOMO3 NOMO1	9.61e-07	8	91	3	15257293
Pubmed	Substrate-driven assembly of a translocon for multipass membrane proteins.	NOMO2 NOMO3 NOMO1	1.44e-06	9	91	3	36261522
Pubmed	An ER translocon for multi-pass membrane protein biogenesis.	NOMO2 NOMO3 NOMO1	2.82e-06	11	91	3	32820719
Pubmed	A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.	PCDH11Y PCDH11X IGSF9 IGSF9B KIT	4.27e-06	91	91	5	28558017
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	NDC1 NF1 NOMO2 MAP3K20 VAV3 IGSF9B MAP3K6 TNS1 PLK4 NOMO3 NOMO1 DYRK2	4.54e-06	910	91	12	36736316
Pubmed	YAC/P1 contigs defining the location of 56 microsatellite markers and several genes across a 3.4-cM interval on mouse chromosome 11.	NF1 ATP1B2 SEZ6	4.86e-06	13	91	3	7626882
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	SRPX2 COL12A1 EPPK1 NF1 DENND1B ACO1 APC KDR GAPDHS CSMD1 AKIP1 ZNF281 PLK4 OLR1	6.63e-06	1293	91	14	15342556
Pubmed	Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer.	APC NOTCH1	6.77e-06	2	91	2	22863622
Pubmed	Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis.	SETD2 APC	6.77e-06	2	91	2	28825595
Pubmed	Conservation of PCDHX in mammals; expression of human X/Y genes predominantly in brain.	PCDH11Y PCDH11X	6.77e-06	2	91	2	11003707
Pubmed	MRCKβ links Dasm1 to actin rearrangements to promote dendrite development.	IGSF9 CDC42BPB	6.77e-06	2	91	2	33933448
Pubmed	Pcdh11x Negatively Regulates Dendritic Branching.	PCDH11Y PCDH11X	6.77e-06	2	91	2	25687328
Pubmed	Notch1 modulates oxidative stress induced cell death through suppression of apoptosis signal-regulating kinase 1.	NOTCH1 MAP3K5	6.77e-06	2	91	2	23569274
Pubmed	A protective role of mast cells in intestinal tumorigenesis.	APC KIT	6.77e-06	2	91	2	18258601
Pubmed	The landscape of genetic mutations in patients with chronic lymphocytic leukaemia and complex karyotype.	SETD2 NOTCH1	6.77e-06	2	91	2	31344256
Pubmed	Identification of SETD2-NF1 fusion gene in a pediatric spindle cell tumor with the chromosomal translocation t(3;17)(p21;q12).	SETD2 NF1	6.77e-06	2	91	2	28498454
Pubmed	Cadherin expression delineates the divisions of the postnatal and adult mouse amygdala.	PCDH11Y PCDH11X	6.77e-06	2	91	2	22592879
Pubmed	Protocadherin X ( PCDHX) and Y ( PCDHY) genes; multiple mRNA isoforms encoding variant signal peptides and cytoplasmic domains.	PCDH11Y PCDH11X	6.77e-06	2	91	2	14727141
Pubmed	Lack of association between protocadherin 11-X/Y (PCDH11X and PCDH11Y) polymorphisms and late onset Alzheimer's disease.	PCDH11Y PCDH11X	6.77e-06	2	91	2	21276771
Pubmed	VEGF receptor Flk-1 plays an important role in c-kit expression in adipose tissue derived stem cells.	KDR KIT	6.77e-06	2	91	2	17850794
Pubmed	Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow.	NF1 KIT	6.77e-06	2	91	2	18984156
Pubmed	Leukemic potential of doubly mutant Nf1 and Wv hematopoietic cells.	NF1 KIT	6.77e-06	2	91	2	12393498
Pubmed	Accelerated evolution of Protocadherin11X/Y: a candidate gene-pair for cerebral asymmetry and language.	PCDH11Y PCDH11X	6.77e-06	2	91	2	16874762
Pubmed	PCDH11 is X/Y homologous in Homo sapiens but not in Gorilla gorilla and Pan troglodytes.	PCDH11Y PCDH11X	6.77e-06	2	91	2	16825765
Pubmed	The protocadherin 11X/Y (PCDH11X/Y) gene pair as determinant of cerebral asymmetry in modern Homo sapiens.	PCDH11Y PCDH11X	6.77e-06	2	91	2	23600975
Pubmed	A comparative analysis of the pig, mouse, and human PCDHX genes.	PCDH11Y PCDH11X	6.77e-06	2	91	2	15112107
Pubmed	Protocadherin 11X/Y a human-specific gene pair: an immunohistochemical survey of fetal and adult brains.	PCDH11Y PCDH11X	6.77e-06	2	91	2	22744706
Pubmed	ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.	MAP3K6 MAP3K5	6.77e-06	2	91	2	19214184
Pubmed	Increased gene copy number of KIT and VEGFR2 at 4q12 in primary breast cancer is related to an aggressive phenotype and impaired prognosis.	KDR KIT	6.77e-06	2	91	2	22170730
Pubmed	ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis.	ETS2 KDR	6.77e-06	2	91	2	15806151
Pubmed	Quantitative analysis of alternative transcripts of human PCDH11X/Y genes.	PCDH11Y PCDH11X	6.77e-06	2	91	2	19859901
Pubmed	Absence of gene mutations in KIT-positive carcinoma showing thymus-like elements of the thyroid.	CD5 KIT	6.77e-06	2	91	2	21835435
Pubmed	The KDR (VEGFR-2) Genetic Polymorphism Q472H and c-KIT Polymorphism M541L Are Associated With More Aggressive Behaviour in Astrocytic Gliomas.	KDR KIT	6.77e-06	2	91	2	33099473
Pubmed	Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1.	MAP3K6 MAP3K5	6.77e-06	2	91	2	17210579
Pubmed	Generation of functional blood vessels from a single c-kit+ adult vascular endothelial stem cell.	KDR KIT	6.77e-06	2	91	2	23091420
Pubmed	MAPKKK6, a novel mitogen-activated protein kinase kinase kinase, that associates with MAPKKK5.	MAP3K6 MAP3K5	6.77e-06	2	91	2	9875215
Pubmed	MAP3Ks as central regulators of cell fate during development.	MAP3K15 MAP3K6 MAP3K5	7.71e-06	15	91	3	18855897
Pubmed	Identification of two new members of the CSMD gene family.	CSMD1 CSMD3	2.03e-05	3	91	2	12906867
Pubmed	Amplification and overexpression of KIT, PDGFRA, and VEGFR2 in medulloblastomas and primitive neuroectodermal tumors.	KDR KIT	2.03e-05	3	91	2	19779861
Pubmed	Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia.	NF1 NOTCH1	2.03e-05	3	91	2	26002977
Pubmed	Lineage tracing of Notch1-expressing cells in intestinal tumours reveals a distinct population of cancer stem cells.	APC NOTCH1	2.03e-05	3	91	2	30696875
Pubmed	Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells.	KDR KIT	2.03e-05	3	91	2	15166028
Pubmed	Notch-1, c-kit and GFRalpha-1 are developmentally regulated markers for premeiotic germ cells.	KIT NOTCH1	2.03e-05	3	91	2	15237212
Pubmed	Characterization of SVEP1, KIAA, and SRPX2 in an in vitro cell culture model of endotoxemia.	SRPX2 SVEP1	2.03e-05	3	91	2	20236627
Pubmed	Delta-like ligand 4 regulates vascular endothelial growth factor receptor 2-driven luteal angiogenesis through induction of a tip/stalk phenotype in proliferating endothelial cells.	KDR NOTCH1	2.03e-05	3	91	2	24074756
Pubmed	Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo.	NF1 KIT	2.03e-05	3	91	2	10620616
Pubmed	The Wsh and Ph mutations affect the c-kit expression profile: c-kit misexpression in embryogenesis impairs melanogenesis in Wsh and Ph mutant mice.	KDR KIT	2.03e-05	3	91	2	7537375
Pubmed	Distinct phenotypic differences associated with differential amplification of receptor tyrosine kinase genes at 4q12 in glioblastoma.	KDR KIT	2.03e-05	3	91	2	23990986
Pubmed	The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response.	MAP3K6 MAP3K5	2.03e-05	3	91	2	26243192
Pubmed	Combinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouse.	NID1 KDR	2.03e-05	3	91	2	12569129
Pubmed	Increased survival following tumorigenesis in Ts65Dn mice that model Down syndrome.	NF1 ETS2	2.03e-05	3	91	2	21467166
Pubmed	Type B3 thymic epithelial tumor in an adolescent detected by immunohistochemical staining for CD5, CD99, and KIT (CD117): a case report.	CD5 KIT	2.03e-05	3	91	2	19901887
Pubmed	The three receptor tyrosine kinases c-KIT, VEGFR2 and PDGFRα, closely spaced at 4q12, show increased protein expression in triple-negative breast cancer.	KDR KIT	2.03e-05	3	91	2	25025175
Pubmed	Cadherin expression in the somatosensory cortex: evidence for a combinatorial molecular code at the single-cell level.	PCDH11Y PCDH11X	2.03e-05	3	91	2	21129452
Pubmed	Amplification of the PDGFRA, KIT and KDR genes in glioblastoma: a population-based study.	KDR KIT	2.03e-05	3	91	2	21382095
Pubmed	Structural analysis of chromosomal rearrangements associated with the developmental mutations Ph, W19H, and Rw on mouse chromosome 5.	KDR KIT	2.03e-05	3	91	2	8041773
Pubmed	PDGFRA, KIT, and KDR Gene Amplification in Glioblastoma: Heterogeneity and Clinical Significance.	KDR KIT	2.03e-05	3	91	2	37610648
Pubmed	Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma.	NF1 KIT	2.03e-05	3	91	2	28296713
Pubmed	Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE.	APC NOTCH1	2.03e-05	3	91	2	17215306
Pubmed	ASK1/2 signaling promotes inflammation in a mouse model of neutrophilic dermatosis.	MAP3K6 MAP3K5	2.03e-05	3	91	2	29629899
Pubmed	Where and what is the right shift factor or cerebral dominance gene? A critique of Francks et al. (2007).	PCDH11Y PCDH11X	2.03e-05	3	91	2	19125366
Pubmed	Gene conversion-like missense mutations in the human cationic trypsinogen gene and insights into the molecular evolution of the human trypsinogen family.	PRSS3P2 PRSS2	2.03e-05	3	91	2	11073713
Pubmed	The origin of trypsin: evidence for multiple gene duplications in trypsins.	PRSS3P2 PRSS2	2.03e-05	3	91	2	9732462
Pubmed	Neurofibromin as a regulator of melanocyte development and differentiation.	NF1 KIT	2.03e-05	3	91	2	18089649
Pubmed	The role of Notch signaling in diabetic endothelial progenitor cells dysfunction.	KDR NOTCH1	2.03e-05	3	91	2	26598222
Pubmed	Non-clustered protocadherin.	PCDH11Y PCDH11X	2.03e-05	3	91	2	21173574
Pubmed	Expressions of PDGF receptor alpha, c-Kit and Flk1 genes clustering in mouse chromosome 5 define distinct subsets of nascent mesodermal cells.	KDR KIT	2.03e-05	3	91	2	9493833
Pubmed	Role of PAX-8, CD5, and CD117 in distinguishing thymic carcinoma from poorly differentiated lung carcinoma.	CD5 KIT	2.03e-05	3	91	2	23958552
Pubmed	Genetic mutations associated with cigarette smoking in pancreatic cancer.	NF1 APC KIT NOTCH1	2.32e-05	63	91	4	19351817
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	MSRA PLEKHH1 DENND1B SLC35A4 PCDH11Y KLHL23 OBSCN RBM5 ZBTB8A IGSF9 IGSF9B CSMD1 CDC42BPB ADSS1	3.19e-05	1489	91	14	28611215
Pubmed	Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.	SETD2 NF1 APC KIT	3.73e-05	71	91	4	28319113
Pubmed	Notch1 is essential for postimplantation development in mice.	KDR NOTCH1	4.05e-05	4	91	2	7926761
Pubmed	β-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress.	MAP3K6 MAP3K5	4.05e-05	4	91	2	30031111
Pubmed	Hemogenic endothelial cell specification requires c-Kit, Notch signaling, and p27-mediated cell-cycle control.	KIT NOTCH1	4.05e-05	4	91	2	24331925
Pubmed	Frequent deletion of CDKN2A and recurrent coamplification of KIT, PDGFRA, and KDR in fibrosarcoma of bone--an array comparative genomic hybridization study.	KDR KIT	4.05e-05	4	91	2	19862822
Pubmed	Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine.	APC NOTCH1	4.05e-05	4	91	2	19251639
Pubmed	The 4q12 amplicon in malignant peripheral nerve sheath tumors: consequences on gene expression and implications for sunitinib treatment.	KDR KIT	4.05e-05	4	91	2	20686603
Pubmed	VEGFR3 is required for button junction formation in lymphatic vessels.	KDR NOTCH1	4.05e-05	4	91	2	37454290
Pubmed	Nf1-/- Schwann cell-conditioned medium modulates mast cell degranulation by c-Kit-mediated hyperactivation of phosphatidylinositol 3-kinase.	NF1 KIT	4.05e-05	4	91	2	21037083
Pubmed	Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells.	NF1 KIT	4.05e-05	4	91	2	18768391
Pubmed	Dual engagement of 14-3-3 proteins controls signal relay from ASK2 to the ASK1 signalosome.	MAP3K6 MAP3K5	4.05e-05	4	91	2	19935702
Pubmed	Maintenance of hematopoietic stem and progenitor cells in fetal intra-aortic hematopoietic clusters by the Sox17-Notch1-Hes1 axis.	KIT NOTCH1	4.05e-05	4	91	2	29458175
Pubmed	Phase I dose escalation study of telatinib, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor 2 and 3, platelet-derived growth factor receptor beta, and c-Kit, in patients with advanced or metastatic solid tumors.	KDR KIT	4.05e-05	4	91	2	19636022
Pubmed	The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma.	APC KIT	4.05e-05	4	91	2	29422500
Pubmed	Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior.	NF1 NOTCH1	4.05e-05	4	91	2	28423318
Pubmed	The protein dendrite arborization and synapse maturation 1 (Dasm-1) is dispensable for dendrite arborization.	IGSF9 IGSF9B	4.05e-05	4	91	2	18268009
Pubmed	Mast cells are an essential hematopoietic component for polyp development.	APC KIT	4.05e-05	4	91	2	18077429
Pubmed	Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions.	APC NOTCH1	4.05e-05	4	91	2	23776410
Pubmed	CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer.	APC KDR	4.05e-05	4	91	2	16567391
Pubmed	A 1.8-Mb YAC contig spanning three members of the receptor tyrosine kinase gene family (Pdgfra, Kit, and Flk1) on mouse chromosome 5.	KDR KIT	4.05e-05	4	91	2	7540588
Pubmed	Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model.	NF1 KIT	4.05e-05	4	91	2	26732977
Pubmed	ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease.	MAP3K6 MAP3K5	4.05e-05	4	91	2	18327563
Pubmed	Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors.	KIT NOTCH1	4.05e-05	4	91	2	28009085
Pubmed	Reconstruction of phrenic neuron identity in embryonic stem cell-derived motor neurons.	PCDH11Y PCDH11X NOTCH1	4.84e-05	27	91	3	24496616
Cytoband	4q11-q12	KDR KIT	1.16e-05	3	91	2	4q11-q12
Cytoband	16p13	SYNGR3 NOMO3	2.99e-04	13	91	2	16p13
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SRPX2 CSMD1 CSMD3 SVEP1 MASP2 SEZ6 CFHR4	7.17e-10	57	60	7	1179
GeneFamily	Fibronectin type III domain containing	FNDC3B FNDC1 COL12A1 COL20A1 OBSCN IGSF9 IGSF9B USH2A	5.46e-08	160	60	8	555
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K20 MAP3K15 MAP3K6 MAP3K5	1.11e-06	24	60	4	654
GeneFamily	Adenosine receptors\|V-set domain containing	PIGR KDR IGSF9B CD276 SIRPG	2.05e-04	163	60	5	590
GeneFamily	Non-clustered protocadherins	PCDH11Y PCDH11X	7.00e-04	12	60	2	21
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	OBSCN IGSF9 KDR IGSF9B	2.00e-03	161	60	4	593
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PCDH11X APC CSMD1 TNS1	3.06e-03	181	60	4	694
GeneFamily	Immunoglobulin like domain containing	IGSF9 KDR IGSF9B KIT	3.85e-03	193	60	4	594
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	KDR KIT	7.79e-03	40	60	2	321
GeneFamily	C1-set domain containing	HLA-DMB SIRPG	8.56e-03	42	60	2	591
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	CD5 KDR KIT CD276 SIRPG	9.81e-03	394	60	5	471
GeneFamily	Collagens	COL12A1 COL20A1	1.02e-02	46	60	2	490
Coexpression	DESCARTES_FETAL_HEART_SATB2_LRRC7_POSITIVE_CELLS	MSRA PCDH11Y PCDH11X CSMD1 CSMD3 SEZ6	2.88e-06	115	90	6	M40201
Coexpression	GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP	MSRA CUTA SETD2 NF1 NOMO3 DYRK2 SIRPG	5.37e-06	197	90	7	M5295
ToppCell	10x5'-GI_small-bowel-Myeloid_Monocytic\|GI_small-bowel / Manually curated celltypes from each tissue	PLBD1 DMXL2 MAP3K20 ETS2 NFAM1 OLR1	1.32e-06	171	90	6	098a7fd387357c0d4e1a6169af4d24ef95b30018
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FNDC1 AASS PCDH11X OBSCN NID1 CSMD3	1.46e-06	174	90	6	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	10x5'-GI_small-bowel-Myeloid_Monocytic-Classical_monocytes\|GI_small-bowel / Manually curated celltypes from each tissue	PLBD1 DMXL2 MAP3K20 ETS2 NFAM1 OLR1	1.46e-06	174	90	6	05d54a36772f096047521e16a89cc42ae48d2a1d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FNDC1 PCDH11X ATP1B2 KIT SVEP1 SEZ6	1.51e-06	175	90	6	9d09636a103daa8f622c3dbfd1f1536aaec3b6bb
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 PCDH11X OBSCN CSMD1 CSMD3 USH2A	2.02e-06	184	90	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 PCDH11X OBSCN CSMD1 CSMD3 USH2A	2.02e-06	184	90	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 PCDH11X OBSCN CSMD1 CSMD3 USH2A	2.02e-06	184	90	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC1 SCCPDH KDR VAV3 MAP3K6 DYRK2	2.36e-06	189	90	6	09dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	FNDC3B SRPX2 COL12A1 SCCPDH NID1 SVEP1	2.43e-06	190	90	6	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	LV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	FNDC3B SRPX2 COL12A1 SCCPDH NID1 SVEP1	2.51e-06	191	90	6	d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCell	IPF-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	SRPX2 NOMO2 PCDH11Y NOMO3 MAP3K5 NOMO1	2.58e-06	192	90	6	e911e286da26202853f9650ba3cdefe5a5c9b585
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	SRPX2 NOMO2 CSMD1 NOMO3 MAP3K5 NOMO1	2.58e-06	192	90	6	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	Monocytes\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	DMXL2 HLA-DMB ETS2 NFAM1 OLR1 FRMD4B	2.91e-06	196	90	6	ab0a8f5f388c9794d7f41f99fb0a5f2fd6fff6b3
ToppCell	Monocytes-IL1B+_Monocytes\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	DMXL2 HLA-DMB ETS2 NFAM1 OLR1 FRMD4B	2.91e-06	196	90	6	7bc0735d324ac5a1661434cda4116ddd58296730
ToppCell	COVID-19-Myeloid-Transitioning_MDM\|COVID-19 / group, cell type (main and fine annotations)	DMXL2 HLA-DMB ETS2 VAV3 NFAM1 OLR1	2.91e-06	196	90	6	4929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PLBD1 SCCPDH HLA-DMB ACO1 CDC42BPB OLR1	2.99e-06	197	90	6	d8ef5cb88dd66e112cb94217b9ad5cd70164f1d0
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLBD1 SCCPDH HLA-DMB ACO1 CDC42BPB OLR1	2.99e-06	197	90	6	33f2fe101ae5744eea3915add37e60aa398bb97f
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLBD1 SCCPDH HLA-DMB ACO1 CDC42BPB OLR1	2.99e-06	197	90	6	5e9a3932ae5147a3d73dc70f1545926a692930ed
ToppCell	Severe_COVID-19-Myeloid-TRAM2\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	PLBD1 SCCPDH HLA-DMB ACO1 CDC42BPB OLR1	2.99e-06	197	90	6	8a126cfe1529f3d75a806aa492743314a8a43ef9
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PLBD1 SCCPDH HLA-DMB ACO1 CDC42BPB OLR1	2.99e-06	197	90	6	9262785807faeb32417fad7ef202405053e453e2
ToppCell	COPD-Myeloid-Macrophage\|COPD / Disease state, Lineage and Cell class	DMXL2 HLA-DMB ETS2 NFAM1 OLR1 FRMD4B	3.17e-06	199	90	6	4b9c53fb4f44190d2f6ad4d52b13be01ebe4955e
ToppCell	control-HLA-DR+_CD83+_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FNDC3B PLBD1 DMXL2 HLA-DMB NFAM1 CDC42BPB	3.17e-06	199	90	6	f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCell	BAL-Severe-cDC_0\|Severe / Compartment, Disease Groups and Clusters	PLBD1 DMXL2 SCCPDH NFAM1 OLR1 CD276	3.17e-06	199	90	6	d39be8b173156bf87baddd3caed4b35597c53ea1
ToppCell	10x5'-Lung-Myeloid_Mac-Alveolar_macrophages\|Lung / Manually curated celltypes from each tissue	PLBD1 SCCPDH HLA-DMB CDC42BPB OLR1 CD276	3.27e-06	200	90	6	3b236900df407bf5a8c44e76d003a7a37d251db6
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PCDH11X ILDR1 CDC42BPB FRMD4B SIRPG	1.84e-05	160	90	5	c2b5fadb4bac17fafc08831f6d3f4ff96ada7e70
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	COL20A1 WSCD2 IGSF9 MAP3K15 KIT	2.01e-05	163	90	5	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	RIOX2 IRF2BP1 COL20A1 AASS SEZ6	2.39e-05	169	90	5	29db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCell	droplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN IGSF9 KDR IL17D TNS1	2.39e-05	169	90	5	7962165cab84af73d20b56eb70b1ed87c94025ef
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	RIOX2 IRF2BP1 COL20A1 AASS SEZ6	2.39e-05	169	90	5	b1611e61f635f8f9b87250e026ad30999cbee041
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	DMXL2 SYNGR3 OBSCN VAV3 FRMD4B	2.46e-05	170	90	5	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD5 ZFR2 SYNGR3 IGSF9 MAP3K15	2.53e-05	171	90	5	6f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD5 ZFR2 SYNGR3 IGSF9 MAP3K15	2.53e-05	171	90	5	ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 HLA-DMB CSMD1 CSMD3 USH2A	2.83e-05	175	90	5	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FNDC1 ATP1B2 KIT SVEP1 SEZ6	2.99e-05	177	90	5	84116796ca4c7007508c0f1a68a1135c7b922278
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FNDC1 ATP1B2 KIT SVEP1 SEZ6	3.07e-05	178	90	5	2a36475c260088f69f3b8c282d910e5eaa5c5c2d
ToppCell	COVID-19_Mild-NK_CD56bright\|COVID-19_Mild / Disease condition and Cell class	HLA-DMB KLHL23 VAV3 KIT NOTCH1	3.15e-05	179	90	5	90e7a4af195aa2332b07a9f06cde63e72ff49255
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SRPX2 COL12A1 ATP1B2 SVEP1 SEZ6	3.15e-05	179	90	5	01302505816f272243659e20d751b61a198a2fc0
ToppCell	normal_Lung-Fibroblasts-Pericytes\|normal_Lung / Location, Cell class and cell subclass	SRPX2 COL12A1 KLHL23 OBSCN NID1	3.32e-05	181	90	5	f74941e49950027360d71ea3b205fc20c6929766
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FNDC1 ATP1B2 KIT SVEP1 SEZ6	3.32e-05	181	90	5	062f00736eed96e4f4327615d093558dd7d82b20
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC1 SRPX2 COL12A1 NID1 SVEP1	3.32e-05	181	90	5	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC1 SRPX2 COL12A1 COL20A1 ATP1B2	3.32e-05	181	90	5	0b1e7335648823b1d83bdfa878ccd44efe7bba9a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC1 SRPX2 COL12A1 NID1 SVEP1	3.32e-05	181	90	5	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Neutrophils\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLBD1 DMXL2 RUBCNL NFAM1 OLR1	3.41e-05	182	90	5	243c783675df495ea4112dbf710712c44ea6b4f1
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FNDC1 SRPX2 COL12A1 NID1 SVEP1	3.41e-05	182	90	5	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Neutrophils-Neutrophils\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLBD1 DMXL2 RUBCNL NFAM1 OLR1	3.41e-05	182	90	5	18790a394dc32b3cef99cdbf826392c520e38b4a
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL20A1 PCDH11X IGSF9 IGSF9B ATP1B2	3.41e-05	182	90	5	c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA4 COL20A1 CSMD1 ATP1B2 CSMD3	3.50e-05	183	90	5	2cf36ad89584eb9f8b04de52a1b511b7f3527884
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA4 COL20A1 CSMD1 ATP1B2 CSMD3	3.50e-05	183	90	5	98fee6838acfaee5e2e449ba088764ec06b8bc57
ToppCell	COPD-Stromal-Pericyte\|COPD / Disease state, Lineage and Cell class	AASS KLHL23 NID1 ATP1B2 TNS1	3.59e-05	184	90	5	a56264a22dfc2d3672b20134ab7c3c7c23da5ae1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRPX2 COL12A1 NID1 SVEP1 CDHR4	3.59e-05	184	90	5	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA4 COL20A1 CSMD1 ATP1B2 CSMD3	3.59e-05	184	90	5	da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCell	facs-Marrow\|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSRA PLBD1 NFAM1 KIT ADSS1	3.69e-05	185	90	5	e40f0a0439834c3025d6c7832977be4e37a94c44
ToppCell	normal-na-Myeloid-conventional_dendritic_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	PLBD1 HLA-DMB MAP3K20 ETS2 OLR1	3.69e-05	185	90	5	67e881a89a491665b8c612fff084c202c0c79235
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FNDC1 ATP1B2 KIT SVEP1 SEZ6	3.69e-05	185	90	5	0b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ETS2 CSMD1 CSMD3 NFAM1 USH2A	3.78e-05	186	90	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_naive-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLBD1 MAP3K20 ETS2 NID1 NFAM1	3.88e-05	187	90	5	3b1439018e265a61d9599e307a202e3c2f60ed32
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_naive\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLBD1 MAP3K20 ETS2 NID1 NFAM1	3.88e-05	187	90	5	e99bc27d212c74da37770297122a4b30445ccd0d
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL20A1 KLHL23 PCDH11X CSMD1 ATP1B2	3.88e-05	187	90	5	8e8b147258982b359447add5027318f5b6d51963
ToppCell	Healthy-HSPC\|World / disease group, cell group and cell class	PRSS2 SCCPDH KLHL23 ZBTB8A KIT	3.88e-05	187	90	5	8cd9e5499e5c2b2321ecbcf780df37fe0f165ac9
ToppCell	LPS-IL1RA+antiTNF-Myeloid\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLBD1 DMXL2 RUBCNL NFAM1 OLR1	3.88e-05	187	90	5	4e0bbef6ba0d1b3e1f8d900d4a9dbd41f09a7bc5
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	SRPX2 MAP3K20 NID1 TNS1 SVEP1	3.98e-05	188	90	5	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FNDC1 COL12A1 NOTUM KLHL23 MAP3K20	3.98e-05	188	90	5	f54b063025d80de631382bf5326bc40aab7f7d00
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KLHL23 OBSCN NID1 TNS1 FRMD4B	3.98e-05	188	90	5	ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell	Control\|World / Disease state, Lineage and Cell class	FNDC3B DMXL2 ETS2 PGC OLR1	4.08e-05	189	90	5	fb8dddd3b901081c6bb9ed6f32dafc5cce5f30be
ToppCell	COVID-19_Severe-HSPC\|COVID-19_Severe / disease group, cell group and cell class	PRSS2 SCCPDH KLHL23 ZBTB8A KIT	4.08e-05	189	90	5	96015439971e2e5b8d6294ca5a6b873c7774e925
ToppCell	3'_v3-GI_small-bowel-Myeloid_Monocytic-Classical_monocytes\|GI_small-bowel / Manually curated celltypes from each tissue	PLBD1 DMXL2 MAP3K20 NFAM1 OLR1	4.08e-05	189	90	5	74a5e61cd820f2495dde40e766c771a31d8c4e7d
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL20A1 PIWIL4 CSMD1 ATP1B2 CSMD3	4.19e-05	190	90	5	ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FNDC1 COL12A1 NOTUM KLHL23 MAP3K20	4.19e-05	190	90	5	938d1f66094b1c94606e0d40213a39e5112f3322
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF9B CSMD1 IL17D CD276 SEZ6	4.19e-05	190	90	5	9b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF9B CSMD1 IL17D CD276 SEZ6	4.19e-05	190	90	5	d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL20A1 PIWIL4 CSMD1 ATP1B2 CSMD3	4.19e-05	190	90	5	4971857eac9af17d66d673ed2ab7072639f60a10
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 SCCPDH KDR VAV3 MAP3K6	4.29e-05	191	90	5	df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC1 SRPX2 KLHL23 NID1 SVEP1	4.29e-05	191	90	5	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PLBD1 SCCPDH HLA-DMB ACO1 CDC42BPB	4.29e-05	191	90	5	2b10a73c5d80e83d67a7121fb004a1aa86a537ef
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRPX2 COL12A1 NID1 SVEP1 MAP3K5	4.29e-05	191	90	5	1caf726bd07fdca389e678fc16304a6ef1790423
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PLBD1 SCCPDH HLA-DMB ACO1 CDC42BPB	4.29e-05	191	90	5	02e1ae144da7274171e055356d10e8d175c5347f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC1 SRPX2 COL12A1 NID1 SVEP1	4.29e-05	191	90	5	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	Severe_COVID-19-Myeloid-TRAM3\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	PLBD1 SCCPDH HLA-DMB ACO1 CDC42BPB	4.29e-05	191	90	5	05867b96199a46a415848409130697c810d18937
ToppCell	BAL-Severe-Myeloid-TRAM\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PLBD1 SCCPDH ACO1 CDC42BPB OLR1	4.29e-05	191	90	5	4c4f50a502e3f6768a89df686fa2830b83b8b33f
ToppCell	BAL-Severe-Myeloid-TRAM\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLBD1 SCCPDH ACO1 CDC42BPB OLR1	4.29e-05	191	90	5	de7c88bb46f794291025ef121a89fcd94dea4ffe
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRPX2 COL12A1 NID1 SVEP1 MAP3K5	4.29e-05	191	90	5	3d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC1 SRPX2 COL12A1 NID1 SVEP1	4.29e-05	191	90	5	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRPX2 COL12A1 NID1 SVEP1 MAP3K5	4.40e-05	192	90	5	4022f208eb5db760abd0aac782a25e8ab63efc64
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC1 SRPX2 NID1 CSMD1 SVEP1	4.40e-05	192	90	5	853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC3B FNDC1 SRPX2 NID1 SVEP1	4.40e-05	192	90	5	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADCY10 SRPX2 COL12A1 MAP3K20 NID1	4.40e-05	192	90	5	fee99ca7e658963acf968aa724ef8c96cfc00a5d
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FNDC1 COL12A1 PCDH11X NID1 SVEP1	4.40e-05	192	90	5	f053b89bfd6048c227667ff01c38df7c51d8a496
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLBD1 SCCPDH HLA-DMB ACO1 CDC42BPB	4.40e-05	192	90	5	34505a13b8a47c9286c560122fa7861b9c331a08
ToppCell	COVID-19-Myeloid-TRAM1\|COVID-19 / Condition, Lineage and Cell class	PLBD1 HLA-DMB ACO1 CDC42BPB OLR1	4.40e-05	192	90	5	52b8578699325b0d35a2d3ba36772096130ccc0c
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLBD1 SCCPDH HLA-DMB ACO1 CDC42BPB	4.40e-05	192	90	5	57c1410ebf90c230993e065eb78385daa3360960
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC3B FNDC1 SRPX2 NID1 SVEP1	4.40e-05	192	90	5	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRPX2 COL12A1 NID1 SVEP1 MAP3K5	4.40e-05	192	90	5	9333aba0d04203ccccad78d82bf6359922f810a7
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC1 SRPX2 NID1 CSMD1 SVEP1	4.40e-05	192	90	5	49281626ecad0456fdbded2378b7028d7b589686
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC1 SRPX2 COL12A1 NID1 SVEP1	4.51e-05	193	90	5	dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell	Macrophages-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	PLBD1 SCCPDH HLA-DMB OLR1 NOTCH1	4.51e-05	193	90	5	7254b730fc4e8b6837601141e37aa39ac680ecbb
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FNDC1 COL12A1 NOTUM KLHL23 MAP3K20	4.51e-05	193	90	5	000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	FNDC3B SRPX2 COL12A1 NID1 SVEP1	4.51e-05	193	90	5	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	IPF-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	PLBD1 SCCPDH ACO1 CDC42BPB OLR1	4.51e-05	193	90	5	03a43b6d235fd47488a6a61efc311a34b232c0f4
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC1 SRPX2 COL12A1 NID1 SVEP1	4.51e-05	193	90	5	e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FNDC1 SRPX2 COL12A1 NID1 SVEP1	4.62e-05	194	90	5	e2db75f4de114631b8bda4e188f84446545538b7
Drug	oxalylglycine	SCCPDH AASS ACO1 AKIP1 OLR1	2.34e-06	54	90	5	CID003080614
Disease	amphetamine abuse (implicated_via_orthology)	MAP3K15 MAP3K6 MAP3K5	4.59e-07	6	85	3	DOID:670 (implicated_via_orthology)
Disease	Malignant Neoplasms	SETD2 APC KDR KIT NOTCH1	3.53e-05	128	85	5	C0006826
Disease	complement factor H-related protein 2 measurement	COL12A1 DENND1B CFHR4	7.99e-05	29	85	3	EFO_0600055
Disease	joint hypermobility measurement	MSRA FNDC1 COL12A1	1.18e-04	33	85	3	EFO_0007905
Disease	Adenocarcinoma of large intestine	APC MAP3K15 KIT CDC42BPB	1.74e-04	96	85	4	C1319315
Disease	Malignant neoplasm of breast	FNDC3B SETD2 NF1 OBSCN ETS2 KDR KIT ZNF281 MAP3K6 TNS1 NOTCH1	2.57e-04	1074	85	11	C0006142
Disease	hemangiopericytoma (is_marker_for)	KDR NOTCH1	2.91e-04	9	85	2	DOID:264 (is_marker_for)
Disease	Glioblastoma Multiforme	NF1 APC NOTCH1 DYRK2	3.04e-04	111	85	4	C1621958
Disease	glucagon-like peptide-1 measurement	COL12A1 CSMD1	3.64e-04	10	85	2	EFO_0008465
Disease	cognitive inhibition measurement	SCCPDH WSCD2 USH2A	4.10e-04	50	85	3	EFO_0007969
Disease	gastrointestinal stromal tumor (is_implicated_in)	SETD2 KIT	4.44e-04	11	85	2	DOID:9253 (is_implicated_in)
Disease	retinopathy of prematurity (biomarker_via_orthology)	KDR NOTCH1	5.31e-04	12	85	2	DOID:13025 (biomarker_via_orthology)
Disease	cholangiocarcinoma (is_marker_for)	PRSS2 KIT NOTCH1	8.47e-04	64	85	3	DOID:4947 (is_marker_for)
Disease	Colorectal Carcinoma	RELCH NF1 PCDH11X OBSCN APC NID1 KDR CSMD3	9.49e-04	702	85	8	C0009402
Disease	Non-Small Cell Lung Carcinoma	PLBD1 APC KDR KIT	1.09e-03	156	85	4	C0007131
Disease	cortical thickness change measurement	CSMD1 FRMD4B	1.22e-03	18	85	2	EFO_0021501
Disease	Glioblastoma	NF1 APC NOTCH1	1.56e-03	79	85	3	C0017636
Disease	cortical surface area measurement	CPA4 MSRA DENND1B APC WSCD2 IGSF9 AKIP1 KIT TNS1 FRMD4B SVEP1	1.64e-03	1345	85	11	EFO_0010736
Disease	Splenomegaly	APC NOTCH1	1.82e-03	22	85	2	C0038002
Disease	Giant Cell Glioblastoma	NF1 APC NOTCH1	1.86e-03	84	85	3	C0334588
Disease	Glioma	NF1 APC ATP1B2	2.05e-03	87	85	3	C0017638
Disease	Cerebral Astrocytoma	NF1 NOTCH1	2.36e-03	25	85	2	C0750935
Disease	Intracranial Astrocytoma	NF1 NOTCH1	2.36e-03	25	85	2	C0750936
Disease	Pilocytic Astrocytoma	NF1 NOTCH1	2.36e-03	25	85	2	C0334583
Disease	Astrocytoma	NF1 NOTCH1	2.36e-03	25	85	2	C0004114
Disease	Juvenile Pilocytic Astrocytoma	NF1 NOTCH1	2.36e-03	25	85	2	C0280783
Disease	Diffuse Astrocytoma	NF1 NOTCH1	2.36e-03	25	85	2	C0280785
Disease	Grade I Astrocytoma	NF1 NOTCH1	2.36e-03	25	85	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	NF1 NOTCH1	2.36e-03	25	85	2	C0205768
Disease	Mixed oligoastrocytoma	NF1 NOTCH1	2.36e-03	25	85	2	C0547065
Disease	Childhood Cerebral Astrocytoma	NF1 NOTCH1	2.36e-03	25	85	2	C0338070
Disease	Gemistocytic astrocytoma	NF1 NOTCH1	2.55e-03	26	85	2	C0334581
Disease	Protoplasmic astrocytoma	NF1 NOTCH1	2.55e-03	26	85	2	C0334580
Disease	Fibrillary Astrocytoma	NF1 NOTCH1	2.55e-03	26	85	2	C0334582
Disease	psychosis predisposition measurement	SFSWAP CSMD1	2.55e-03	26	85	2	EFO_0008337
Disease	nicotine withdrawal measurement	CSMD1 NFAM1	2.75e-03	27	85	2	EFO_0009362
Disease	Anaplastic astrocytoma	NF1 NOTCH1	2.75e-03	27	85	2	C0334579

Protein segments in the cluster

Peptide	Gene	Start	Entry
HIIYCSITGYGQTGP	SUGCT	161	Q9HAC7
LSPGSGVVTYYLQES	ACO1	471	P21399
CGYNVTSQNGTIYSP	CSMD1	2146	Q96PZ7
TVGQTISFECFPGYT	CSMD3	2241	Q7Z407
SGYVPGSVSAAFVTC	CUTA	61	O60888
EVGATIESYISYCGG	AASS	621	Q9UDR5
YPGTYSVTVGSNDLT	AKIP1	176	Q9NQ31
LVTYTPQSSIICYGQ	CD5	96	P06127
VTITCSSYQGYPEAE	CD276	161	Q5ZPR3
GDTVTITCSSYRGYP	CD276	376	Q5ZPR3
NCYSVGSVGDVPFTA	DMXL2	16	Q8TDJ6
YPGIVTCDSVTYNGS	ADCY10	421	Q96PN6
NIEYYTSGGPTTFAV	CDHR4	476	A6H8M9
YSCYGTVSSLNGEPE	NOMO3	961	P69849
YSGYEGCAVLQVSPV	RUBCNL	271	Q9H714
AGGYTSNPTYKEVCS	MSRA	96	Q9UJ68
TVPIYATGVLTCYIQ	RELCH	906	Q9P260
YSCYGTVSSLNGEPE	NOMO2	961	Q5JPE7
GPNTYTCVCTEGYTG	NOTCH1	546	P46531
TIGGPTLVITEYCCY	KIT	661	P10721
STHYGYSTGQPCVFI	ATP1B2	166	P14415
VGSYTLIPYVVTATG	MAP3K6	171	O95382
IPQRAQCIYTGGSSY	NID1	771	P14543
SVSVTYCSVSQDFPG	ETS2	246	P15036
GVYYCTIEAPGDTSG	ILDR1	141	Q86SU0
YSCYGTVSSLNGEPE	NOMO1	961	Q15155
YTEAYVTIPVGCTCV	IL17D	156	Q8TAD2
CSPTHVTVYSEYGVD	CDC42BPB	1471	Q9Y5S2
TCGAHVTVVTVYYVP	OR10G3	241	Q8NGC4
CYGTTIFTYIQPHSG	OR2F2	251	O95006
SDPYSVSDCGYPVTT	PCDH11X	986	Q9BZA7
YQYEVCLTGGPGTSE	PCDHB10	751	Q9UN67
RGAVSQTYPSGTCAY	OLR1	231	P78380
QTYPSGTCAYIQRGA	OLR1	236	P78380
PPGTTESVQSVDYYC	RBM5	216	P52756
SQYTSYAISGPTVQG	PLBD1	501	Q6P4A8
CASSTGAVTSGYYPN	IGLV7-43	41	P04211
ESYGPVTYIVQCSLE	OBSCN	7581	Q5VST9
NTSVTCNDGSPAGYY	NOTUM	96	Q6P988
YCVTPVTGPYYTTQT	FRMD4B	741	Q9Y2L6
ALTPSYGDTYTCVVE	HLA-DMB	181	P28068
ESYGVTCLGPNIYVT	KLHL23	311	Q8NBE8
DTSYTVTVVPVYTEG	COL12A1	1906	Q99715
TYTVRVTCLYPGGGS	COL20A1	621	Q9P218
DIGTSGYSQEVVCYT	FNDC3B	456	Q53EP0
GYSQEVVCYTLGNIP	FNDC3B	461	Q53EP0
ATPGDVVTGYLVYSA	FNDC1	1681	Q4ZHG4
SGTEYQVGPTCTTVY	CPA4	346	Q9UI42
GYEISYGNTTGSIVC	CFHR4	426	Q92496
LPVSETCDTYSYGVV	MAP3K20	181	Q9NYL2
TGPGVTTYKAVIQYS	MASP2	381	O00187
VGSPYVVESTGVYLS	GAPDHS	161	O14556
GTCSSSVQYTPVYKL	DENND1B	476	Q6P3S1
PVSYRGVTYSLTTNC	SPACA4	76	Q8TDM5
YPRYCTVTTLSDGSV	DYRK2	461	Q92630
TEYPCGSGNVYAGVL	IRF2BP1	276	Q8IU81
YSVSDCGYPVTTFEV	PCDH11Y	1021	Q9BZA8
FYGTTIGVYLCPSSV	OR1M1	251	Q8NGA1
GINPCTETFTGTLQY	MAP3K5	831	Q99683
GVNPCTETFTGTLQY	MAP3K15	801	Q6ZN16
GYLGGCTESLPTYVT	USH2A	2801	O75445
GIDVTTYYSTLPAGV	SFSWAP	386	Q12872
GGYTCEENSVPYQVS	PRSS3P2	26	Q8NHM4
TYPFVTSSNCTVGGV	ADSS1	266	Q8N142
PVQYAAYVTVGGITS	SCCPDH	271	Q8NBX0
SSQVTGISRNPYCGY	NXPE3	51	Q969Y0
VTLVLPGASATGTYY	NFAM1	116	Q8NET5
AVTGYTDPYTGQQIS	EPPK1	2306	P58107
AVTGYTDPYTGQQIS	EPPK1	4441	P58107
ISQVACRGTVSPTYY	PIWIL4	771	Q7Z3Z4
ISYTSPNGQTTRYGE	PLK4	926	O00444
ISSITPADVGTYYCV	SIRPG	106	Q9P1W8
TTGPNVVYSCNRGYS	SVEP1	3316	Q4LDE5
VYCVEGTPINFSTAT	APC	1641	P25054
GTCTGIYAAQAYAVP	SLC35A4	71	L0R6Q1
TLSSGYTYPTATGVQ	ZFR2	161	Q9UPR6
TPVGYQYGQGSDVTS	ZBTB8A	256	Q96BR9
GYCTVGVEPTYLSSQ	PGC	341	P20142
ALGTYTCVPYNTLGT	IGSF9B	391	Q9UPX0
PFITSGTYTCTNGVL	SRPX2	126	O60687
VYTSGIYNIPGDSQT	TNS1	216	Q9HBL0
YTTSPLECGFGQSVT	ZNF281	711	Q9Y2X9
EGYLAATYPTVGQTS	NF1	2501	P21359
GTVVTYQCYPGYQVV	SEZ6	731	Q53EL9
GGYICEENSVPYQVS	PRSS2	26	P07478
YPVGSGVEGTETYQS	SYNGR3	196	O43761
VEGNSVSITCYYPPT	PIGR	31	P01833
GEYSCTPYNSLGTAG	IGSF9	391	Q9P2J2
ITYPYSSVTTFGGCR	PLEKHH1	1266	Q9ULM0
CYFGSLVGSNVYITP	RIOX2	156	Q8IUF8
SQATIYYQGQTCPTV	SETD2	2291	Q9BYW2
YYQGQTCPTVYGVTS	SETD2	2296	Q9BYW2
TCPTVYGVTSPYSQT	SETD2	2301	Q9BYW2
PVDSYQYGTTQTLTC	KDR	431	P35968
SCGTPSYFIVYQTQV	WSCD2	311	Q2TBF2
VIYGQYCSGVESAIS	VAV3	276	Q9UKW4
TQGQYSFLVVPCTGT	NDC1	136	Q9BTX1