Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainTeashirt_fam

TSHZ3 TSHZ1

6.50e-063282IPR027008
DomainHomeodomain-like

TSHZ3 TSHZ1 ZNF541

1.31e-02332283IPR009057
Pubmed

Teashirt 3 expression in the chick embryo reveals a remarkable association with tendon development.

TSHZ3 TSHZ1

1.87e-06328216631416
Pubmed

Three putative murine Teashirt orthologues specify trunk structures in Drosophila in the same way as the Drosophila teashirt gene.

TSHZ3 TSHZ1

1.87e-06328214973285
Pubmed

Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction.

TSHZ3 TSHZ1

1.87e-06328219745106
Pubmed

FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4.

TSHZ3 TSHZ1

1.31e-05728219343227
Pubmed

Expression patterns of the three Teashirt-related genes define specific boundaries in the developing and postnatal mouse forebrain.

TSHZ3 TSHZ1

1.74e-05828215834955
Pubmed

The vibrator mutation causes neurodegeneration via reduced expression of PITP alpha: positional complementation cloning and extragenic suppression.

PRPF8 PITPNA

2.24e-0592829182797
Pubmed

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.

TSHZ3 TSHZ1 EIF4G2

6.16e-059528320843830
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

TACC2 PRPF8 RBM27 PDLIM5 YLPM1 EIF4G2

8.38e-0593428633916271
Pubmed

Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse.

TSHZ3 TSHZ1

1.06e-041928231427287
Pubmed

KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.

TACC2 PRPF8 RBM27

1.56e-0413028335545047
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

TNRC6C PRPF8 RBM27 ADARB2

1.65e-0434728416033648
Pubmed

Multimodal Hox5 activity generates motor neuron diversity.

TSHZ3 TSHZ1

2.50e-042928239289460
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

FAM98A PRPF8 RBM27 PDLIM5 YLPM1

2.55e-0472428536232890
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

MRPS30 TSHZ3 GASK1B PDLIM5 ZNF541

3.00e-0475028511230166
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

FAM98A PRPF8 RBM27 YLPM1 EIF4G2

4.19e-0480728522681889
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

PRPF8 RBM27 YLPM1

4.19e-0418228332239614
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

TNRC6C GARRE1 PDLIM5 FAM83B EIF4G2

5.39e-0485328528718761
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

MRPS30 TSHZ3 FAM98A PRPF8 PDLIM5 EIF4G2

5.76e-04133528629229926
Pubmed

A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.

MRPS30 PRPF8

5.79e-044428226471122
Pubmed

BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.

FAM98A PDLIM5 EIF4G2

6.90e-0421628331519766
Pubmed

PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.

PDLIM5 EIF4G2

7.18e-044928231762063
Cytoband17p13.3

PRPF8 SGSM2 PITPNA

2.15e-058828317p13.3
CytobandEnsembl 112 genes in cytogenetic band chr17p13

PRPF8 SGSM2 PITPNA

1.21e-03346283chr17p13
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

TSHZ3 TSHZ1

9.75e-0515182529
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

TMEM132D YLPM1

1.37e-02181182694
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17|GI_large-bowel / Manually curated celltypes from each tissue

ADGRE5 CD5 GASK1B PDLIM5

4.60e-061792846359f30005b17dc5b5c4c8f3a6a38c87ccfe4ee9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE5 TSHZ3 ADARB2 PDLIM5

6.46e-06195284803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE5 TSHZ3 ADARB2 PDLIM5

6.46e-061952844f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TSHZ1 ADARB2 PDLIM5

1.28e-04157283516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCellFrontal_cortex|World / BrainAtlas - Mouse McCarroll V32

TSHZ3 TMEM132D GASK1B

1.46e-04164283e09291711abf8680e78170328313719092b0142f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ3 GASK1B FAM83B

1.59e-041692831c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CACNA1H TACC2 ADARB2

1.62e-0417028314aa86a4f526ed6986afcb28c49225522055550c
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

TSHZ3 ADARB2 FAM83B

1.65e-041712833965ced4be6db14265a90673502fceee425837ca
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

SATL1 TMEM132D ADARB2

1.76e-041752834db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

SATL1 TMEM132D ADARB2

1.76e-041752838d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CACNA1H TACC2 ADARB2

1.79e-0417628305ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD5 TNRC6C GARRE1

1.82e-0417728364b8f665fdaf975558af2ad7d9b54d206de8350c
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TSHZ3 ADARB2 FAM83B

1.82e-04177283ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TSHZ3 ADARB2 FAM83B

1.82e-04177283cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCellCOPD-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

TSHZ3 ADARB2 FAM83B

1.85e-04178283441d1dba720141891b11f404744c59834d80e6c5
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSHZ3 GARRE1 ZNF541

1.89e-04179283d2db9e70b780643f1e004c41a70464d0abe26088
ToppCellControl-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

TSHZ3 ADARB2 FAM83B

2.08e-04185283d5d6d13e2f20b54ca55645b9a757b8599f4fd897
ToppCellE17.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADGRE5 GARRE1 GASK1B

2.14e-04187283e9aa0a5a0f8e2593de63e83b56b53ae33e60af49
ToppCellE17.5-Endothelial-capillary_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADGRE5 GARRE1 GASK1B

2.14e-0418728361b8a53f29bb8b33c69f680b8359a1143a23999d
ToppCellfacs-MAT-Fat-3m|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRPF8 GARRE1 GASK1B

2.18e-041882837da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCellCOVID-19-Epithelial-Ionocytes|COVID-19 / Condition, Lineage and Cell class

CACNA1H TACC2 FAM83B

2.18e-04188283a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCellP03-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADGRE5 GARRE1 PITPNA

2.25e-04190283347c7bf67ade235a4e2320db6a75ce0dab8744f9
ToppCellP03-Endothelial-unknown_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADGRE5 GARRE1 PITPNA

2.25e-041902830c7da05fbd3f095dde7550585209c056f0b76990
ToppCellE17.5-Endothelial|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADGRE5 GARRE1 GASK1B

2.25e-041902834fb76195ec9d6e0260a628eef6c2b3705acce787
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1H ADARB2 PDLIM5

2.32e-041922835000440dc1ed17e7474d340921bdff945646f27e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE5 TSHZ3 ADARB2

2.42e-04195283d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE5 TSHZ3 ADARB2

2.46e-04196283a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE5 TSHZ3 PDLIM5

2.46e-04196283802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE5 TSHZ3 ADARB2

2.46e-041962833e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE5 TSHZ3 PDLIM5

2.46e-04196283fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSHZ3 ADARB2 FAM83B

2.50e-041972831e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE5 TSHZ3 ADARB2

2.50e-04197283b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE5 TSHZ3 ADARB2

2.50e-041972836d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRE5 TSHZ3 ADARB2

2.50e-04197283c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCellEpithelial_cells-Basal_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

TSHZ3 FAM83B HR

2.54e-041982834235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GARRE1 GASK1B PDLIM5

2.57e-0419928362936fb64b33f7ad671f9c610bed665f17d3145e
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GARRE1 GASK1B PDLIM5

2.57e-04199283f53e0e4c34e6aec81ab07593aa11e045ba04df06
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSHZ3 ADARB2 FAM83B

2.57e-04199283f5c3561744e2a0e7716657cb521acb1d8f054b41
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GARRE1 GASK1B ZNF541

2.57e-04199283bd43a84e84d8acb8e1008b98a235cc5bd5f43586
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSHZ3 ADARB2 FAM83B

2.61e-042002838827653738a931e4a4545e0c7d75be12bed40740
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-CD4+_Tem|Leuk-UTI / Disease, condition lineage and cell class

CACNA1H TNRC6C ADARB2

2.61e-0420028365ea3ba16c75f8e9a5aee3ba0c7ab11a961fff7c
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TACC2 ADARB2 PITPNA

2.61e-04200283d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TACC2 ADARB2 PITPNA

2.61e-042002830eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

TSHZ3 ADARB2 EIF4G2

2.61e-04200283c6bbd33bca86ac7a76a7ba704b3e141237d04549
DrugFlurandrenolide [1524-88-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A

ADGRE5 CACNA1H PDLIM5 CIDEC HR

3.85e-061972854702_DN
Diseasemigraine disorder, glucose measurement

CACNA1H SGSM2

3.42e-0431262EFO_0004468, MONDO_0005277
DiseaseBell's palsy

RBM27 EIF4G2

3.64e-03102262EFO_0007167
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

MRPS30 TSHZ3 TACC2 SGSM2

5.01e-03801264EFO_0003888, EFO_0007052, MONDO_0002491

Protein segments in the cluster

PeptideGeneStartEntry
WKPRHGIPNNQKDTV

ADGRE5

241

P48960
QKKQRQWIGPTGMNQ

CD5

411

P06127
PLTKKPWLGKQGNNN

RBM27

571

Q9P2N5
GLGTWVRKPPEQQQF

ADARB2

721

Q9NS39
GPLGPNWKQELVNQK

PITPNA

171

Q00169
AWVKGVNPKGNSTNP

KCNK16

76

Q96T55
PQNGERKVNWLGSKE

HR

81

O43593
LNRTNNPPGNWKKPS

FAM83B

406

Q5T0W9
KQKQPRPWPQLDTGS

LMNTD2

236

Q8IXW0
GVIKSPSWQRPNQGV

PDLIM5

356

Q96HC4
KTPGQNAQKWIPARS

EIF4G2

41

P78344
QKCWQNGRVPKPESG

GASK1B

341

Q6UWH4
LGQKPQGPRNNTWPN

GARRE1

806

O15063
GKWKQVRTNPANIEG

CNTN2

651

Q02246
WRKKVDPSAVQGQGP

CACNA1H

486

O95180
NNPRKNICWGTQSKP

MRPS30

386

Q9NP92
GETLKPGPQQNWASK

TNRC6C

656

Q9HCJ0
RPKKPSQEWGSQEGQ

TMEM132D

826

Q14C87
PWQKRQDGPQQQTGG

FAM98A

321

Q8NCA5
QLEPPLWTQQGKGKV

SGSM2

376

O43147
INQPGMKQPGTWQLG

SATL1

311

Q86VE3
QKGQKWQPPSEQGTR

CIDEC

111

Q96AQ7
NGHIPGWVPVEKNNK

C12orf29

136

Q8N999
EWGRQNTDKGNNPKG

PRPF8

2236

Q6P2Q9
WDNQQENPPPTKKIG

TACC2

2276

O95359
TPAQKRKGRQSNWNP

TSHZ3

886

Q63HK5
QWKGPKPAFGQQHQQ

YLPM1

836

P49750
PVHKRKGRQSNWNPQ

TSHZ1

881

Q6ZSZ6
GNQQNGSPTDWTKPR

ZNF541

821

Q9H0D2